Academic literature on the topic 'Drug addiction – Pathophysiology'

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Journal articles on the topic "Drug addiction – Pathophysiology"

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Shippenberg, T. S., A. Zapata, and V. I. Chefer. "Dynorphin and the pathophysiology of drug addiction." Pharmacology & Therapeutics 116, no. 2 (2007): 306–21. http://dx.doi.org/10.1016/j.pharmthera.2007.06.011.

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Maguire, Denise. "Drug Addiction in Pregnancy: Disease Not Moral Failure." Neonatal Network 33, no. 1 (2013): 11–18. http://dx.doi.org/10.1891/0730-0832.33.1.11.

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Nurses have demonstrated concern for years about their interactions with pregnant women who abuse drugs. Reports of nurses’ concern with substance abuse have been reported in the literature since the 1980s. As with any chronic disease, drug addiction causes physiologic changes, and the pathology that occurs in the brain drives characteristic behaviors. Research suggests that choices that addicts make are driven by pathology rather than by failure of a moral compass. This article reviews the theoretical explanations for addictive behaviors, describes the pathophysiology of drug addiction that i
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Tefahi, B., A. Yahiouche, and F. Kacha. "Adolescence and addiction." European Psychiatry 26, S2 (2011): 115. http://dx.doi.org/10.1016/s0924-9338(11)71826-0.

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Adolescence and addiction are two different entities. Adolescence is a period characterized by a realignment risk of psychic structures, physiological and morphological. It is constructed using a reference model via the values inherited from the parents and new behaviors including consumption of drug abuse “addiction”.We illustrate our presentation with a literature review done on the PubMed database using keywords such as “adolescent, addiction, neurobiologic,pathogenesis, treatment” to study all the parameters that explain the link between adolescence and addiction from a causal model neurob
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Ali, Md Akmat, Farida Yeasmin, and MN Nag. "Addiction and Liver Disease." Medicine Today 25, no. 2 (2014): 75–83. http://dx.doi.org/10.3329/medtoday.v25i2.17926.

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Drug induced liver disease is a global problem. The aims of the study are to know the recreational drugs causing harmful effect on liver, epidemiology of addiction; pathophysiology and their consequences. The major findings published to date concerning different agents causing addiction and liver disease, their implications with regard to understanding disease mechanisms and their amplitude or spectrum are described. Addiction not only invites lot of sufferings to the family and the country, but also responsible for different types of liver disease including fatty liver, hepatitis and liver fa
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Rao, P. S. S., Kelly O’Connell, and Thomas Kyle Finnerty. "Potential Role of Extracellular Vesicles in the Pathophysiology of Drug Addiction." Molecular Neurobiology 55, no. 8 (2018): 6906–13. http://dx.doi.org/10.1007/s12035-018-0912-4.

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Rodrigues, Livia C. M., Pedro H. Gobira, Antonio Carlos de Oliveira, et al. "Neuroinflammation as a possible link between cannabinoids and addiction." Acta Neuropsychiatrica 26, no. 6 (2013): 334–46. http://dx.doi.org/10.1017/neu.2014.24.

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ObjectiveSubstance dependence disorder is a chronically relapsing condition characterised by neurobiological changes leading to loss of control in restricting a substance intake, compulsion and withdrawal syndrome. In the past few years, (endo)cannabinoids have been raised as a possible target in the aetiology of drug addiction. On the other hand, although the exact mechanisms of the genesis of addiction remain poorly understood, it is possible that neuroinflammation might also play a role in the pathophysiology of this condition. Studies demonstrated that (endo)cannabinoids act as immunomodul
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Tsai, Sheng-Tzung, Hock-Kean Liew, Hao-Ming Li, Shinn-Zong Lin, and Shin-Yuan Chen. "Harnessing Neurogenesis and Neuroplasticity with Stem Cell Treatment for Addictive Disorders." Cell Transplantation 28, no. 9-10 (2019): 1127–31. http://dx.doi.org/10.1177/0963689719859299.

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Drug and alcohol addiction has become an emerging public health issue and is a great burden to patients, their families, and society. It is characterized by high relapse rates and significant morbidity and mortality, and most available treatments result in only modest improvement. These findings highlight the necessity for new approaches to treat addiction. Scientific reports in the past two decades suggest that addiction involves impaired neural plasticity and decreased hippocampal neurogenesis. Stem cell therapy and its derived neurotrophic factors can potentially target the underlying patho
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Ivanov, Iliyan S., Kurt P. Schuiz, Robyn C. Palmero, and Jeffrey H. Newcorn. "Neurorobiology and Evidence-Based Biological Treatments for Substance Abuse Disorders." CNS Spectrums 11, no. 11 (2006): 864–77. http://dx.doi.org/10.1017/s1092852900015017.

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ABSTRACTBehavioral patterns of addiction include compulsive drug-seeking, persistent abuse of substances despite the often dire consequences on social functioning and physical health, and the high probability of relapse even after prolonged drug-free periods.The recent focus on the biological basis of addiction has provided evidence to support the hypothesis that behavioral manifestations for addiction are influenced by biological factors, and biological factors often produce behavioral changes that can further increase risk. The current understanding of the role of the dopaminergic, glutamate
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Clasen, Matthew M., Anthony L. Riley, and Terry L. Davidson. "Hippocampal-Dependent Inhibitory Learning and Memory Processes in the Control of Eating and Drug Taking." Current Pharmaceutical Design 26, no. 20 (2020): 2334–52. http://dx.doi.org/10.2174/1381612826666200206091447.

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As manifestations of excessive and uncontrolled intake, obesity and drug addiction have generated much research aimed at identifying common neuroadaptations that could underlie both disorders. Much work has focused on changes in brain reward and motivational circuitry that can overexcite eating and drug-taking behaviors. We suggest that the regulation of both behaviors depends on balancing excitation produced by stimuli associated with food and drug rewards with the behavioral inhibition produced by physiological “satiety” and other stimuli that signal when those rewards are unavailable. Our m
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Buonaguro, E. F., F. Marmo, L. Avvisati, et al. "Opioidergic system and N-methyl D-aspartate receptor (NMDA-R) hypofunction: Translational implications for the pathophysiology of psychosis and drug addiction." European Psychiatry 26, S2 (2011): 1231. http://dx.doi.org/10.1016/s0924-9338(11)72936-4.

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Enkephalin is an opioidergic neuromodulator that has been implicated in long-term behavioural sensitization after administration of drugs of abuse. Enkephalin is also a molecular marker of GABAergic neurons in the striato-pallidal pathway that is involved in sensory-motor gating and has been considered dysfunctional in the pathophysiology of psychosis.In this study we investigated in male Sprague Dawley rats putative changes in Enkephalin transcripts by in situ hybridization after acute or subchronic administration of ketamine in either high or low subanaesthetic doses (50 mg/kg and 12 mg/kg r
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Dissertations / Theses on the topic "Drug addiction – Pathophysiology"

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Villafranca, Steven Wayne. "The effect of early psychostimulant treatment on abuse liability and dopamine receptors." CSUSB ScholarWorks, 2005. https://scholarworks.lib.csusb.edu/etd-project/2824.

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Examines whether the reinforcing properties of drugs of abuse were altered in adulthood by methylphenidate, more commonly known as Ritalin. Subjects were 108 rats of Sprague-Dawley descent (Harlan). Methylphenidate, or saline was administered daily to the subjects from the postnatal period (11-20 days old). The rats preference for morphine during early adulthood was measured using conditioned place preference. The number of dopamine D₂ receptors was measured in each rat and the correlation between receptor number and morphine preference was determined. Results indicate that rats pretreated wit
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Berlanga, Monica Lisa. "Cholinergic interneurons and synaptic reorganization within the nucleus accumbens shell and core: potential neural substrates underlying drug addiction." Thesis, 2006. http://hdl.handle.net/2152/3755.

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Albrecht, Daniel Strakis. "Assessment of the dopamine system in addiction using positron emission tomography." Thesis, 2014. http://hdl.handle.net/1805/5192.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>Drug addiction is a behavioral disorder characterized by impulsive behavior and continued intake of drug in the face of adverse consequences. Millions of people suffer the financial and social consequences of addiction, and yet many of the current therapies for addiction treatment have limited efficacy. Therefore, there is a critical need to characterize the neurobiological substrates of addiction in order to formulate better treatment options. In the first chapter, the striatal dopamine system is interrogated with [11C]raclopride
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Books on the topic "Drug addiction – Pathophysiology"

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Hanson, Dirk. The chemical carousel: What science tells us about beating addiction. Booksurge Publishing, 2008.

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1947-, Byalick Marcia, ed. The craving brain: A bold new approach to breaking free from drug addiction, overeating, alcoholism, gambling. 2nd ed. Perennial/an imprint of HarperCollins Publishers, 2000.

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Luis, Stinus, and Koob George F, eds. Neurobiological mechanisms of opiate withdrawal. Springer, 1996.

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Maldonado, Rafael. Neurobiological mechanisms of opiate withdrawal. Springer, 1996.

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Levinthal, Charles F. Messengers of paradise: Opiates and the brain : the struggle over pain, rage, uncertainty, and addiction. Anchor Press/Doubleday, 1988.

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Cohen, Sidney. The chemical brain: The neurochemistry of addictive disorders. CareInstitute, 1988.

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Ahmed, Serge H., and Boris Gutkin. Computational Neuroscience of Drug Addiction. Springer, 2013.

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Ahmed, Serge H., and Boris Gutkin. Computational Neuroscience of Drug Addiction. Springer, 2011.

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Computational Neuroscience Of Drug Addiction. Springer, 2011.

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Papa, Susan. Amazing Brain - Addiction (Amazing Brain). Blackbirch Press, 2001.

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Book chapters on the topic "Drug addiction – Pathophysiology"

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Hu, Amy, Lintao Jia, Jean-Christian Maillet, and Xia Zhang. "Tat-3L4F: A Novel Peptide for Treating Drug Addiction by Disrupting Interaction Between PTEN and 5-HT2C Receptor." In 5-HT2C Receptors in the Pathophysiology of CNS Disease. Humana Press, 2010. http://dx.doi.org/10.1007/978-1-60761-941-3_16.

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Belin-Rauscent, Aude, and David Beli. "Animal Models of Drug Addiction." In Addictions - From Pathophysiology to Treatment. InTech, 2012. http://dx.doi.org/10.5772/52079.

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Koob, George F., and Michel Le Moal. "Drug Addiction: Transition from Neuroadaptation to Pathophysiology." In Neurobiology of Addiction. Elsevier, 2006. http://dx.doi.org/10.1016/b978-012419239-3/50047-3.

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Ramos-Miguel, Alfredo, Maria Alvaro-Bartolome, M. Julia, and Jesus A. "Role of Multifunctional FADD (Fas-Associated Death Domain) Adaptor in Drug Addiction." In Addictions - From Pathophysiology to Treatment. InTech, 2012. http://dx.doi.org/10.5772/34273.

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De Ridder, Dirk, Patrick Manning, Gavin Cape, Sven Vanneste, Berthold Langguth, and Paul Glue. "Pathophysiology-Based Neuromodulation for Addictions." In Neuropathology of Drug Addictions and Substance Misuse. Elsevier, 2016. http://dx.doi.org/10.1016/b978-0-12-800213-1.00002-x.

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Belin-Rauscent, Aude, and David Beli. "Drug Addictions: An Historical and Ethological Overview." In Addictions - From Pathophysiology to Treatment. InTech, 2012. http://dx.doi.org/10.5772/52165.

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Vicente, Jose, Gonzalo Flores, Talvinder S., and Antonio Rodriguez-Moreno. "Addictive Drugs and Synaptic Plasticity." In Addictions - From Pathophysiology to Treatment. InTech, 2012. http://dx.doi.org/10.5772/33299.

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Aydin, Mustafa, and Ugur Deveci. "Pathophysiology of Ketamine Neurotoxicity." In Neuropathology of Drug Addictions and Substance Misuse. Elsevier, 2016. http://dx.doi.org/10.1016/b978-0-12-800212-4.00052-2.

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Stocco, Paolo, Alessandra Simonelli, Nicoletta Capra, and Francesca De. "Research and Intervention for Drug-Addicted Mothers and Their Children: New Perspectives." In Addictions - From Pathophysiology to Treatment. InTech, 2012. http://dx.doi.org/10.5772/50820.

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Chossegros, Philippe. "HCV and Drug Use – What Can Be Learned from the Failure to Control This Epidemic?" In Addictions - From Pathophysiology to Treatment. InTech, 2012. http://dx.doi.org/10.5772/50836.

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