Academic literature on the topic 'Drug delivery in cancer therapy'

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Journal articles on the topic "Drug delivery in cancer therapy"

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SL, Prabu. "Nano based Drug Delivery System for Cancer Therapy: A Next Generation Theranostics." Bioequivalence & Bioavailability International Journal 6, no. 2 (2022): 1–17. http://dx.doi.org/10.23880/beba-16000178.

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Cancer is considered as one of the foremost cause of illness and death with very complex pathophysiology even though prominent advancement has been made on innovative tumor treatments. Therapeutic properties and the global survival rate are still disappointing for the patients with cancer. There is a shortfall in the capabilities of these cancer therapies, some novel strategies are developed to provide better treatment therapies to improve their quality of life and also aids in reducing the number of deaths. Amongst the cardinal phases towards ensuring ideal cancer management is early diagnosi
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Yadav, Neena, Arul Prakash Francis, Veeraraghavan Vishnu Priya, et al. "Polysaccharide-Drug Conjugates: A Tool for Enhanced Cancer Therapy." Polymers 14, no. 5 (2022): 950. http://dx.doi.org/10.3390/polym14050950.

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Cancer is one of the most widespread deadly diseases, following cardiovascular disease, worldwide. Chemotherapy is widely used in combination with surgery, hormone and radiation therapy to treat various cancers. However, chemotherapeutic drugs can cause severe side effects due to non-specific targeting, poor bioavailability, low therapeutic indices, and high dose requirements. Several drug carriers successfully overcome these issues and deliver drugs to the desired sites, reducing the side effects. Among various drug delivery systems, polysaccharide-based carriers that target only the cancer c
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Subhan, Md Abdus, and Vladimir P. Torchilin. "Advances in Targeted Therapy of Breast Cancer with Antibody-Drug Conjugate." Pharmaceutics 15, no. 4 (2023): 1242. http://dx.doi.org/10.3390/pharmaceutics15041242.

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Antibody–drug conjugates (ADCs) are a potential and promising therapy for a wide variety of cancers, including breast cancer. ADC-based drugs represent a rapidly growing field of breast cancer therapy. Various ADC drug therapies have progressed over the past decade and have generated diverse opportunities for designing of state-of-the-art ADCs. Clinical progress with ADCs for the targeted therapy of breast cancer have shown promise. Off-target toxicities and drug resistance to ADC-based therapy have hampered effective therapy development due to the intracellular mechanism of action and limited
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Anitha, P., J. Bhargavi, G. Sravani, B. Aruna, and Ramkanth S. "RECENT PROGRESS OF DENDRIMERS IN DRUG DELIVERY FOR CANCER THERAPY." International Journal of Applied Pharmaceutics 10, no. 5 (2018): 34. http://dx.doi.org/10.22159/ijap.2018v10i5.27075.

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With the recent advances of nanotechnology, dendrimers are emerging as a highly attractive class of drug delivery vectors for cancer therapy. Dendrimers are multifunctional smart Nanocarriers to deliver one or more therapeutic agent safely and selectively to cancer cells. The high level of control over the synthesis of dendritic architecture makes dendrimers a nearly perfect (spherical) nanocarrier for site-specific drug delivery. The presence of functional groups in the dendrimers exterior also permits the addition of other moieties that can actively target certain diseases which are now wide
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Vasir, Jaspreet K., and Vinod Labhasetwar. "Targeted Drug Delivery in Cancer Therapy." Technology in Cancer Research & Treatment 4, no. 4 (2005): 363–74. http://dx.doi.org/10.1177/153303460500400405.

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Chemotherapy has been the main modality of treatment for cancer patients; however, its success rate remains low, primarily due to limited accessibility of drugs to the tumor tissue, their intolerable toxicity, development of multi-drug resistance, and the dynamic heterogeneous biology of the growing tumors. Better understanding of tumor biology in recent years and new targeted drug delivery approaches that are being explored using different nanosystems and bioconjugates provide optimism in developing successful cancer therapy. This article reviews the possibilities and challenges for targeted
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P, Mohmed Fauzith, Balaji T, Bala Krishnan P, and John Felix S.N. "Nanotechnology-Future Prospects of Sperm-Driven Therapy in Oncology - A Review Article." International Journal of Health Sciences and Research 15, no. 2 (2025): 100–105. https://doi.org/10.52403/ijhsr.20250212.

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Cancer is a major fatal disease worldwide, with millions of new cases and deaths each year. While treatments like chemotherapy and immunotherapy have saved many lives, they often come with severe side effects. A better solution being developed targeted drug delivery, which aims to deliver medication directly to cancer cells, which increasing the effectiveness of the treatment and reducing harmful side effects. One fascinating approach under development is sperm-loaded nanotherapy. This innovative method uses sperm cells as natural carriers for cancer drugs. Because sperm can move efficiently t
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., Sebastine, and Mohamed Zerein Fathima. "Nanosuspensions in Breast Cancer Therapy: A Comprehensive Overview." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 14, no. 02 (2024): 1090–98. http://dx.doi.org/10.25258/ijddt.14.2.73.

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Nanosuspensions offer a promising avenue for enhancing breast cancer treatment through improved drug delivery, solubility, and targeting. These colloidal dispersions contain submicron drug particles, significantly increasing surface area and enhancing drug solubility and dissolution rates. This improvement can lead to increased drug bioavailability, enabling lower doses and reduced side effects. It is also possible to engineer nanosuspensions so that they are controlled-release drugs, providing sustained therapeutic levels at the tumor site. Nanosuspensions facilitate targeted drug delivery, w
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Singh, Amit. "Advancements in Nanotechnology: Revolutionizing Drug Delivery Systems for Precision Targeted Cancer Therapy." Journal of Scientific Advances 1, no. 1 (2024): 23–33. https://doi.org/10.63665/jsa.v1i1.01.

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Nanotechnology has emerged as a transformative approach in medicine, particularly in the field of targeted cancer therapy. This paper explores advancements in nanotechnology that have significantly improved drug delivery systems, allowing for more precise targeting of cancer cells while minimizing the side effects typically associated with traditional chemotherapy. The study highlights various nanocarrier systems, including liposomes, nanoparticles, and dendrimers, discussing their mechanisms of action, advantages, and potential challenges in clinical applications. The findings suggest that na
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Montané, Xavier, Anna Bajek, Krzysztof Roszkowski, et al. "Encapsulation for Cancer Therapy." Molecules 25, no. 7 (2020): 1605. http://dx.doi.org/10.3390/molecules25071605.

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The current rapid advancement of numerous nanotechnology tools is being employed in treatment of many terminal diseases such as cancer. Nanocapsules (NCs) containing an anti-cancer drug offer a very promising alternative to conventional treatments, mostly due to their targeted delivery and precise action, and thereby they can be used in distinct applications: as biosensors or in medical imaging, allowing for cancer detection as well as agents/carriers in targeted drug delivery. The possibility of using different systems—inorganic nanoparticles, dendrimers, proteins, polymeric micelles, liposom
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Yu, Han, Na Ning, Xi Meng, Chuda Chittasupho, Lingling Jiang, and Yunqi Zhao. "Sequential Drug Delivery in Targeted Cancer Therapy." Pharmaceutics 14, no. 3 (2022): 573. http://dx.doi.org/10.3390/pharmaceutics14030573.

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Cancer is a major public health problem and one of the leading causes of death. However, traditional cancer therapy may damage normal cells and cause side effects. Many targeted drug delivery platforms have been developed to overcome the limitations of the free form of therapeutics and biological barriers. The commonly used cancer cell surface targets are CD44, matrix metalloproteinase-2, folate receptors, etc. Once the drug enters the cell, active delivery of the drug molecule to its final destination is still preferred. The subcellular targeting strategies include using glucocorticoid recept
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Dissertations / Theses on the topic "Drug delivery in cancer therapy"

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Yung, Bryant Chinung. "NANOPARTICLE DRUG DELIVERY SYSTEMS FOR CANCER THERAPY." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1417614665.

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Zi, Hong. "Polymers for drug delivery in cancer therapy /." May be available electronically:, 2008. http://proquest.umi.com/login?COPT=REJTPTU1MTUmSU5UPTAmVkVSPTI=&clientId=12498.

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Liu, Yang. "Development of Novel Drug Delivery Systems for Cancer Therapy." The Ohio State University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=osu153105342400785.

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Xu, Leyuan. "Engineering of Polyamidoamine Dendrimers for Cancer Therapy." VCU Scholars Compass, 2015. http://scholarscompass.vcu.edu/etd/3773.

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Dendrimers are a class of polymers with a highly branched, three-dimensional architecture comprised of an initiator core, several interior layers of repeating units, and multiple active surface terminal groups. Dendrimers have been recognized as the most versatile compositionally and structurally controlled nanoscale building blocks for drug and gene delivery. Polyamidoamine (PAMAM) dendrimers have been most investigated because of their unique structures and properties. Polycationic PAMAM dendrimers form compacted polyplexes with nucleic acids at physiological pH, holding great potential for
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Qin, Yiru. "Graphene Quantum Dots-Based Drug Delivery for Ovarian Cancer Therapy." Scholar Commons, 2016. http://scholarcommons.usf.edu/etd/6358.

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Ovarian cancer, one of the most dreadful malignancies of the female reproductive system, poses a lethal threat to women worldwide. In this dissertation, the objective was to introduce a novel type of graphene quantum dots (GQDs) based nano-sized drug delivery systems (DDS) for ovarian cancer treatment. As a starting point, the facile synthesis method of the GQDs was established. Subsequently, the targeting ligand,folic acid (FA), was conjugated to GQDs. Next, a FDA approved chemotherapeutic drug, Doxorubicin (DOX), was loaded to form the GQDs-FA-DOX nano-conjugation as the DDS. Moreover, the u
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Man, Kwun-wai Dede, and 文冠慧. "Oleanolic acid delivery using biodegradable nanoparticles for cancer therapy." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2015. http://hdl.handle.net/10722/208550.

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Escolà, Jané Anna. "Somatostatin analogues as drug delivery systems for receptor-targeted cancer therapy." Doctoral thesis, Universitat de Barcelona, 2018. http://hdl.handle.net/10803/663804.

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Somatostatin (SST or SRIF14) is a peptidic hormone secreted throughout the central nervous system and in the gastrointestinal tract which has anti-secretory, anti-proliferative and anti-angiogenic effects. Although its administration as a drug is effective in certain conditions, its therapeutic use is limited by its short plasma half-life (< 3 min), the broad spectrum of biological responses and the lack of selectivity over its receptors (SSTRs). In order to obtain more stable and selective analogues we have incorporated both non-natural electron-rich and electron-poor aromatic amino acids at
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Riaz, Muhammad Kashif. "Peptide functionalized drug delivery system for an efficient lung cancer therapy." HKBU Institutional Repository, 2019. https://repository.hkbu.edu.hk/etd_oa/609.

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Lung cancer has a high incidence rate globally and the leading cause of cancer related mortalities. In 2018, lung cancer has been estimated to cause 1.76 million deaths worldwide (18.33% of total cancer mortalities). In Hong Kong lung cancer has been a leading cause of cancer related deaths, and in 2016 caused 3780 deaths (26.6% of total cancer mortalities). Non-small cell lung cancer (NSCLC) is the major (~85%) lung cancer type, and five-year survival rate for lung cancer has estimated to be 18%. Thus, an efficient lung cancer treatment with lesser adverse effects is need of the hour. In this
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KALAJA, ODETA. "Nanoparticles based delivery System of Flavonoids for Cancer Therapy." Doctoral thesis, Università degli Studi di Trieste, 2018. http://hdl.handle.net/11368/2917683.

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Nowadays, cancer remains one of the major public health problem. Although chemotherapeutic drugs efficiently kill cancer cells, these cells can defend themselves from such toxic compounds with a process called cancer multidrug resistance (MDR). Because of unsatisfactory treatment scenario there has been growing interest in the health advantages of using plant-derived compounds for cancer prevention or in the treatment of chemo-resistant cells. Anthocyanidins are a group of pigments belonging to the family of flavonoids present in red-blue fruits and vegetables. Several studies demonstrated tha
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Cheng, Yu. "Gold Nanoparticles as Drug Delivery Vectors for Photodynamic Therapy of Cancers." Case Western Reserve University School of Graduate Studies / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=case1301503263.

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Books on the topic "Drug delivery in cancer therapy"

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Brown, Dennis M. Drug Delivery Systems in Cancer Therapy. Humana Press, 2003. http://dx.doi.org/10.1385/1592594271.

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Khan, Firdos Alam, ed. Nano Drug Delivery for Cancer Therapy. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-6940-1.

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Brown, Dennis M., ed. Drug Delivery Systems in Cancer Therapy. Humana Press, 2004. https://doi.org/10.1007/978-1-59259-427-6.

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Razelle, Kurzrock, and Markman Maurie, eds. Targeted cancer therapy. Humana Press, 2008.

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Feng, Tao, and Yanli Zhao. Nanomaterial-Based Drug Delivery Carriers for Cancer Therapy. Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-3299-8.

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Senter, Peter, Felix Kratz, and Henning Steinhagen. Drug delivery in oncology: From basic research to cancer therapy. Wiley-VCH, 2012.

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Gutiérrez, Lucía M. Neuro-oncology and cancer targeted therapy. Nova Biomedical Books, 2010.

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M, Amiji Mansoor, ed. Nanotechnology for cancer therapy. CRC/Taylor & Francis, 2007.

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missing], [name. Tumor targeting in cancer therapy. Humana Press, 2003.

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Toshiwo, Andoh, ed. DNA topoisomerases in cancer therapy: Present and future. Kluwer Academic/Plenum Publishers, 2003.

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Book chapters on the topic "Drug delivery in cancer therapy"

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Alexis, Frank, Eric M. Pridgen, Robert Langer, and Omid C. Farokhzad. "Nanoparticle Technologies for Cancer Therapy." In Drug Delivery. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-00477-3_2.

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Alley, Stephen C., Simone Jeger, Robert P. Lyon, Django Sussman, and Peter D. Senter. "Empowered Antibodies for Cancer Therapy." In Drug Delivery in Oncology. Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527634057.ch10.

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Sankar, Renu, V. K. Ameena Shirin, Chinnu Sabu, and K. Pramod. "Carbon Nanotubes in Cancer Therapy." In Drug Delivery Using Nanomaterials. CRC Press, 2021. http://dx.doi.org/10.1201/9781003168584-12.

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Ma, Yifan, Jingjing Zhang, Yuan Yuan, Harshvardhan Modh, and Zhaogang Yang. "Combined Therapy in Cancer Treatment." In Drug Delivery to Tumors. Springer Nature Singapore, 2025. https://doi.org/10.1007/978-981-19-8930-8_4.

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Zhu, Zhenping, and Daniel J. Hicklin. "Antibody-Mediated Drug Delivery in Cancer Therapy." In Cellular Drug Delivery. Humana Press, 2004. http://dx.doi.org/10.1007/978-1-59259-745-1_17.

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Yhee, Ji Young, Sejin Son, Sohee Son, Min Kyung Joo, and Ick Chan Kwon. "The EPR Effect in Cancer Therapy." In Cancer Targeted Drug Delivery. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-7876-8_23.

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Matsumura, Yasuhiro, Masahiro Yasunaga, and Shino Manabe. "Cancer Stromal Targeting (CAST) Therapy and Tailored Antibody Drug Conjugate Therapy Depending on the Nature of Tumor Stroma." In Cancer Targeted Drug Delivery. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-7876-8_6.

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Osanto, Susanne. "Gene Therapy of Cancer." In Drug Delivery Systems in Cancer Therapy. Humana Press, 2004. https://doi.org/10.1007/978-1-59259-427-6_14.

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Birnbaum, Duane T., and Lisa Brannon-Peppas. "Microparticle Drug Delivery Systems." In Drug Delivery Systems in Cancer Therapy. Humana Press, 2004. https://doi.org/10.1007/978-1-59259-427-6_6.

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Barar, Jaleh, Yadollah Omidi, and Gumbleton Mark. "Molecular Targeted Therapy of Lung Cancer: Challenges and Promises." In Pulmonary Drug Delivery. John Wiley & Sons, Ltd, 2015. http://dx.doi.org/10.1002/9781118799536.ch12.

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Conference papers on the topic "Drug delivery in cancer therapy"

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Langley, Andrew, Allison Sweeney, Christopher Nguyen, Skye Edwards, Deeksha Sankepalle, and Srivalleesha Mallidi. "Non-invasive simultaneous assessment of therapy-induced tumor microenvironmental changes in collagen and vasculature with photoacoustic imaging." In Optical Molecular Probes, Imaging and Drug Delivery. Optica Publishing Group, 2025. https://doi.org/10.1364/omp.2025.om5e.2.

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The tumor microenvironment (TME) is critical for tumor cell survival and metastasis, comprising both cellular (immune and stromal cells) and non-cellular (extracellular matrix, ECM) components. Collagen within the ECM, produced by cancer-associated fibroblasts, fosters aggressive tumor phenotypes and confers resistance to chemotherapy. To enhance the efficacy of cancer therapies, various innovative strategies are being developed to normalize or target tumor collagen. We have previously demonstrated that photodynamic therapy (PDT) at low doses, termed photodynamic priming (PDP), can degrade col
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Domey, Ernestina, Md Nafiz Hannan, Zihao Li, and Timothy M. Baran. "Fluorescence spectroscopy of a targeted photosensitizer for photodynamic therapy of breast cancer." In Frontiers in Optics. Optica Publishing Group, 2024. https://doi.org/10.1364/fio.2024.jtu4a.67.

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This study validated a fluorescence spectroscopy system for improved real-time monitoring of photodynamic therapy in murine breast cancer models, with a focus on precise drug delivery and tumor response to optimize treatment protocols.
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Carigga Gutierrez, Nazareth M., Ahmed G. Abdelhamid, Amandine Hurbin, Anne-Laure Bulin, Jean-Luc Coll, and Mans Broekgaarden. "Applying photodynamics for radiotherapy-controlled drug delivery." In Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXXIII, edited by David H. Kessel, Tayyaba Hasan, and Edward V. Maytin. SPIE, 2025. https://doi.org/10.1117/12.3040703.

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Pannem, Sanjana, Yichen Feng, Sassan Hodge, et al. "Advancing Paired Agent Imaging for Head and Neck Cancer." In Optical Molecular Probes, Imaging and Drug Delivery. Optica Publishing Group, 2025. https://doi.org/10.1364/omp.2025.oth1d.3.

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Paired Agent Imaging was tested in in vivo mouse models, demonstrating consistent binding potential (BP) quantification across increasing dosage, stable BP quantification at timepoints &gt;5h, and no significant effects due to injection methodology.
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Sinsuebphon, Nattawut, Alena Rudkouskaya, Margarida Barroso, and Xavier Intes. "Whole body lifetime FRET imaging in transmission and reflectance for the assessment of drug delivery efficacy in small animals." In Cancer Imaging and Therapy. OSA, 2016. http://dx.doi.org/10.1364/cancer.2016.jm3a.48.

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Madhusudhanan, J., P. Arivazhagi, J. Balavignesh, and K. Sathish Kumar. "Invivo drug delivery for cancer therapy using gold nanoparticle." In International Conference on Advanced Nanomaterials & Emerging Engineering Technologies (ICANMEET-2013). IEEE, 2013. http://dx.doi.org/10.1109/icanmeet.2013.6609399.

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Inai, Mizuho, Masaya Yamauchi, Norihiro Honda, et al. "Hemagglutinating virus of Japan envelope (HVJ-E) allows targeted and efficient delivery of photosensitizer for photodynamic therapy against advanced prostate cancer." In Optical Molecular Probes, Imaging and Drug Delivery. OSA, 2015. http://dx.doi.org/10.1364/omp.2015.om2d.3.

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Chizenga, Elvin Peter, and Heidi Abrahamse. "Enhancing Photodynamic Therapy of Cancer by Intracellular Delivery of Photosensitizer." In Frontiers in Optics. Optica Publishing Group, 2022. http://dx.doi.org/10.1364/fio.2022.jtu5a.67.

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Immunogenic proteins in cancer are relevant targets for drug delivery. A multifunctional photo-activating compound directed to such proteins was developed for Photodynamic Therapy of Human Papillomavirus-transformed cancer cells. Selective binding increased therapeutic efficacy by two-folds.
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Weerathunga, Dulanga, and Koshala Chathuri De Silva. "NANOTECHNOLOGY BASED TARGETED DRUG DELIVERY SYSTEMS IN BREAST CANCER THERAPY." In International Conference on Bioscience and Biotechnology. The International Institute of Knowledge Management (TIIKM), 2017. http://dx.doi.org/10.17501/biotech.2017.2105.

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Rajeswari, N. Raja, and P. Malliga. "Microfluidic system using microneedles for targeted drug delivery in cancer therapy." In 2013 IEEE International Conference on Smart Structures and Systems (ICSSS). IEEE, 2013. http://dx.doi.org/10.1109/icsss.2013.6623000.

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Reports on the topic "Drug delivery in cancer therapy"

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Esenaliev, Rinat O. Novel Drug Delivery Technique for Breast Cancer Therapy. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada410175.

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Esenaliev, Rinat O. Novel Drug Delivery Technique for Breast Cancer Therapy. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada435264.

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Esenaliev, Rinat O. Novel Drug Delivery Technique for Breast Cancer Therapy. Defense Technical Information Center, 2003. http://dx.doi.org/10.21236/ada418735.

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Band, Hamid, Srikumar Raja, and Tatiana Bronich. Mechanism-Based Enhanced Delivery of Drug-Loaded Targeted Nanoparticles for Breast Cancer Therapy. Defense Technical Information Center, 2013. http://dx.doi.org/10.21236/ada577110.

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Bronich, Tatiana, Hamid Band, and Srikumar Raja. Mechanism-Based Enhanced Delivery of Drug-Loaded Targeted Nanoparticles for Breast Cancer Therapy. Defense Technical Information Center, 2013. http://dx.doi.org/10.21236/ada580965.

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Band, Hamid, and Tatiana Bronich. Mechanism-Based Enhanced Delivery of Drug-Loaded Targeted Nanoparticles for Breast Cancer Therapy. Defense Technical Information Center, 2014. http://dx.doi.org/10.21236/ada599969.

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Bronich, Tatiana, and Hamid Band. Mechanism-Based Enhanced Delivery of Drug-Loaded Targeted Nanoparticles for Breast Cancer Therapy. Defense Technical Information Center, 2014. http://dx.doi.org/10.21236/ada600027.

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Wang, Paul C. A Partnership Training Program: Studying Targeted Drug Delivery Using Nanoparticles in Breast Cancer Diagnosis and Therapy. Defense Technical Information Center, 2014. http://dx.doi.org/10.21236/ada613187.

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Wang, Paul C. A Partnership Training Program: Studying Targeted Drug Delivery Using Nanoparticles in Breast Cancer Diagnosis and Therapy. Defense Technical Information Center, 2012. http://dx.doi.org/10.21236/ada568802.

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Wang, Paul C. A Partnership Training Program: Studying Targeted Drug Delivery Using Nanoparticles in Breast Cancer Diagnosis and Therapy. Defense Technical Information Center, 2013. http://dx.doi.org/10.21236/ada597692.

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