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Books on the topic 'Drug discovery process'

Author: Grafiati

Published: 4 June 2021

Last updated: 13 February 2022

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1

Smith, Charles G. The process of new drug discovery and development. CRC Press, 1992.

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2

Mohan, C. Gopi, ed. Structural Bioinformatics: Applications in Preclinical Drug Discovery Process. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-05282-9.

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3

Innovation in the pharmaceutical industry: The process of drug discovery and development. E. Elgar, 2003.

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4

Pharmaceutical process chemistry for synthesis: Rethinking the routes to scale-up. Wiley, 2011.

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5

Pharmacology in drug discovery: Understanding drug response. Academic Press, 2012.

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6

Kenakin, Terrence P. Pharmacology in drug discovery: Understanding drug response. Academic Press, 2012.

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7

Cooke, J. R. Management of technical change in the speeding up of the dryg discovery process: A case study. UMIST, 1997.

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8

Mitosis: Methods and protocols. Humana Press, 2009.

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9

Managing the Drug Discovery Process. Elsevier, 2017. http://dx.doi.org/10.1016/c2014-0-01958-2.

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10

Medicinal Chemistry: The Modern Drug Discovery Process. Pearson Higher Education & Professional Group, 2012.

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11

Stevens, Erland. Medicinal Chemistry: The Modern Drug Discovery Process. Pearson Education, Limited, 2013.

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12

G, Smith Charles, and O'Donnell James Pharm D, eds. The process of new drug discovery and development. 2nd ed. Informa Healthcare, 2006.

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13

The process of new drug discovery and development. 2nd ed. Informa Healthcare, 2005.

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14

Mohan, C. Gopi. Structural Bioinformatics: Applications in Preclinical Drug Discovery Process. Springer, 2019.

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15

Smith, Charles G., and James T. O'Donnell, eds. The Process of New Drug Discovery and Development. CRC Press, 2006. http://dx.doi.org/10.1201/9781420004236.

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16

(Editor), Charles G. Smith, and James T. O'Donnell (Editor), eds. The Process of New Drug Discovery and Development, Second Edition. 2nd ed. Informa Healthcare, 2006.

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17

Miller, Susan, Barbara Munk, Walter Moos, and Stephen Munk. Managing the Drug Discovery Process: How to Make It More Efficient and Cost-Effective. Elsevier Science & Technology, 2016.

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18

Li, Jie Jack. Top Drugs. Oxford University Press, 2015. http://dx.doi.org/10.1093/oso/9780199362585.001.0001.

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Drugs like Lipitor, Plavix, Taxol, and Zoloft are integral in today's medicinal world. These widely used products save lives and improve the quality of lives, playing a crucial role in everything from cholesterol management to cancer treatment. These advances in medicine were brought into existence after nuanced process of creation, featuring a wide range of chemical and pharmacological experimentation and discovery. Top Drugs: Their History, Pharmacology, and Synthesis provides an in-depth study on ten prominent drugs, outlining the chemistry behind each one's creation. Jie Jack Li, a medicin

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19

Harrington, Peter J. Pharmaceutical Process Chemistry for Synthesis: Rethinking the Routes to Scale-Up. Wiley & Sons, Incorporated, John, 2011.

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20

Harrington, Peter J. Pharmaceutical Process Chemistry for Synthesis: Rethinking the Routes to Scale-Up. Wiley & Sons, Incorporated, John, 2010.

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21

Harrington, Peter J. Pharmaceutical Process Chemistry for Synthesis: Rethinking the Routes to Scale-Up. Wiley & Sons, Incorporated, John, 2011.

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22

Li, Jie Jack. Blockbuster Drugs. Oxford University Press, 2014. http://dx.doi.org/10.1093/oso/9780199737680.001.0001.

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For the world's largest prescription drug manufacturers, the last few years have been a harrowing time. Recently, Pfizer's Lipitor, GlaxoSmithKline's Advair, AstraZeneca's Seroquel, and Sanofi-Aventis and Bristol-Myers Squibb's Plavix all came off patent in the crucial U.S. market. This so-called "patent cliff" meant hundreds of billions of dollars in lost revenue and has pharmaceutical developers scrambling to create new drugs and litigating to extend current patent protections. Having spent most of his career in drug discovery in "big pharma," Dr. Li now delivers an insider's account of how

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23

Cordes, Eugene H. Hallelujah Moments. 2nd ed. Oxford University Press, 2020. http://dx.doi.org/10.1093/oso/9780190080457.001.0001.

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This work provides eleven stories of drug discovery and features the scientists who made them. The outcome of the discovery work has provided novel therapies in cancer, cardiovascular medicine, antibacterial and antiviral infectious diseases, parasitic diseases, metabolic diseases, and weight control. Each story begins with the basic biomedical science that revealed the pathway to effective drug therapy and continues with the step-by-step process that leads from insight to a product in clinical practice meeting a defined medical need. The tales feature creative problem-solving by clever and de

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24

Michelson, Seth, and Daniel L. Young. Systems Biology in Drug Discovery and Development. Wiley & Sons, Incorporated, John, 2011.

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25

Michelson, Seth, and Daniel L. Young. Systems Biology in Drug Discovery and Development. Wiley & Sons, Incorporated, John, 2012.

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26

Michelson, Seth, and Daniel L. Young. Systems Biology in Drug Discovery and Development. Wiley & Sons, Incorporated, John, 2011.

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27

Systems Biology In Drug Discovery And Development. John Wiley & Sons, 2011.

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28

Abdel-Magid, Ahmed F., American Chemical Society Staff, Jaan A. Pesti, Rajappa Vaidyanathan, and Division of Organic Chemistry Staff American Chemical Society. Comprehensive Accounts of Pharmaceutical Research and Development: From Discovery to Late-Stage Process Development. Oxford University Press, Incorporated, 2018.

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29

Abdel-Magid, Ahmed F., American Chemical Society Staff, Jaan A. Pesti, Rajappa Vaidyanathan, and Division of Organic Chemistry Staff American Chemical Society. Comprehensive Accounts of Pharmaceutical Research and Development: From Discovery to Late-Stage Process Development. Oxford University Press, Incorporated, 2018.

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30

Collis, Brad. Fields of Discovery. CSIRO Publishing, 2002. http://dx.doi.org/10.1071/9780643100961.

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At the cutting edge of international research and development, the Commonwealth Scientific and Industrial Research Organisation, CSIRO, has been at the forefront of some of the most extraordinary technological and scientific advances in the world during the second half of the twentieth century. Based on hundreds of interviews and meticulous research, Fields of Discovery tells the many stories of achievements and successes of the CSIRO and the people who contributed to them. Brad Collis follows their triumphs and frustrations, opening a rare window into the laboratories of knowledge-makin

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31

Griep, Mark A., and Marjorie L. Mikasen. ReAction! Oxford University Press, 2009. http://dx.doi.org/10.1093/oso/9780195326925.001.0001.

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ReAction! gives a scientist's and artist's response to the dark and bright sides of chemistry found in 140 films, most of them contemporary Hollywood feature films but also a few documentaries, shorts, silents, and international films. Even though there are some examples of screen chemistry between the actors and of behind-the-scenes special effects, this book is really about the chemistry when it is part of the narrative. It is about the dualities of Dr. Jekyll vs. inventor chemists, the invisible man vs. forensic chemists, chemical weapons vs. classroom chemistry, chemical companies that kno

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32

Natural Products: Discourse, Diversity, and Design. Wiley-Blackwell, 2014.

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33

Schmidt, Dieter, and Simon Shorvon. Is the End of Epilepsy in Sight? Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198725909.003.0008.

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The best proxy for the end of epilepsy is the complete cessation of seizures and the permanent ending of the need for further treatment. This marks the end of the biology of epilepsy, but not necessarily of all its societal consequences. The good news is that today over 80% of people developing epilepsy will reach this goal after a few years of treatment. Unfortunately, though, not all patients can reach this point, and it is for these patients that we seek improvements in the future. The end of epilepsy is not always easy to predict at the beginning. The taking of drugs is an issue, as always

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34

Fattorusso, Ernesto, William H. Gerwick, and Orazio Taglialatela-Scafati. Handbook of Marine Natural Products. Springer, 2012.

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35

Fattorusso, Ernesto, William H. Gerwick, and Orazio Taglialatela-Scafati. Handbook of Marine Natural Products. Springer, 2012.

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36

Applying Lean Six Sigma in the Pharmaceutical Industry. Routledge, 2014.

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37

Wójcik-Gładysz, Anna. Ghrelin – hormone with many faces. Central regulation and therapy. The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, 2020. http://dx.doi.org/10.22358/mono_awg_2020.

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Discovered in 1999, ghrelin, is one of the peptides co-creating the hypothalamicgastrointestinal axis, otherwise known as the brain-gut axis. Ghrelin participates in many physiological processes and spectrum of its activity is still being discovered. This 28 amino acid peptide ‒ a product of the ghrl gene, was found in all vertebrates and is synthesized and secreted mainly from enteroendocrine X/A cells located in the gastric mucosa of the stomach. Expression of the ghrelin receptor has been found in many nuclei of the hypothalamus involved in appetite regulation. Therefore it’s presumed that

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