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Journal articles on the topic 'Drug effects on vas deferens'

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1

Muzi-Filho, Humberto, Dominick Rodrigues Alves de Souza, Christianne Bretas Vieira Scaramello, and Valeria Do Monti Nascimento Cunha. "Ivermectin as an inhibitor of the plasma membrane and the sarcoplasmic/endoplasmic reticulum Ca2+-ATPases in rat vas deferens." Revista de Ciências Médicas 23, no. 2 (2014): 75. http://dx.doi.org/10.24220/2318-0897v23n2a2526.

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ObjectiveThe present work investigated the effect of ivermectin on Ca2+ content and on the Ca2+-ATPase activity (represented by the plasma membrane Ca2+-ATPase and the sarcoplasmic/endoplasmic reticulum Ca2+-ATPase present in rat vas deferens.MethodsThe assays were carried out using ultracentrifuged homogenate preparations from rat vas deferens in the presence or absence of the 12-kDa FK506-binding protein-Ca2+ release channel complex. Measures of Ca2+ content and Ca2+ ATPase activity were then carried out in function of different concentrations of ivermectin. ResultsThe data show that ivermec
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2

McCulloch, Cameron R., and David Pollock. "Effects of chronic drug treatment on the sensitivity of mouse vas deferens to drugs." European Journal of Pharmacology 118, no. 3 (1985): 253–61. http://dx.doi.org/10.1016/0014-2999(85)90136-0.

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3

Chen, Y. F., Y. T. Lin, T. W. Tan, and H. Y. Tsai. "Effects of veratrine and paeoniflorin on isolated mouse vas deferens." Phytomedicine 9, no. 4 (2002): 296–301. http://dx.doi.org/10.1078/0944-7113-00122.

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4

Hambe, Cyprien Magloire, Marie Ngaha Njila, Hubert Kenmogne, Brice Landry Koloko, and Dieudonne Massoma Lembe. "EFFECTS OF AQUEOUS STEM BARK EXTRACT OF XYLOPIA AETHIOPICA ON THE REPRODUCTIVE FUNCTIONS OF MALE RATS." International Journal of Pharmacy and Pharmaceutical Sciences 10, no. 1 (2018): 113. http://dx.doi.org/10.22159/ijpps.2018v10i1.22038.

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Objective: The sexual stimulatory effect of aqueous stem bark extract of Xylopia aethiopica which is commonly used traditionally for the treatment of fertility-related problems in males is reported in this work.Methods: The present study investigated the effect of 14 d oral administration of 1 ml/kg distilled water (control), 100, 200 and 300 mg/kg of body weight of the stem bark extract on some fertility parameters of the Swiss male rats. So, all the target organs (testis, epididymis, vas deferens, seminal vesicle and prostate) were weighed. The sperm motility and sperm count in testis, epidi
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5

Parvardeh, Siavash, and Mohammad Fatehi. "Effects of Thymoquinone, the Major Constituent ofNigella sativaSeeds, on the Contractile Responses of Rat vas Deferens." Pharmaceutical Biology 41, no. 8 (2003): 616–21. http://dx.doi.org/10.1080/13880200390502135.

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6

Villar, R., M. Laguna, I. Cadavid, and J. Calleja. "Effects of Aqueous Extracts of Six Marine Microalgae on Smooth Muscle Contraction in Rat Duodenum and Vas Deferens." Planta Medica 60, no. 06 (1994): 521–26. http://dx.doi.org/10.1055/s-2006-959563.

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7

Boselli, C., and E. Grana. "Differential effects of drugs interacting with autonomic transmitters on responses of rat vas deferens to field stimulation." Journal of Autonomic Pharmacology 20, no. 2 (2000): 87–98. http://dx.doi.org/10.1046/j.1365-2680.2000.00176.x.

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8

Amobi, N. I. B., and I. C. H. Smith. "Differential effects of calcium channel blockers on the responses of the rat vas deferens to intramural nerve stimulation and exogenous drugs." Experientia 42, no. 4 (1986): 410–12. http://dx.doi.org/10.1007/bf02118633.

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9

Bourreau, Jean-Pierre, та Robert Tricoche. "Prejunctional α2-adrenergic properties of S-3341 (dicyclopropylmethyl)amino-2-Δ-2-oxazoline: a comparison with clonidine". Canadian Journal of Physiology and Pharmacology 65, № 12 (1987): 2496–99. http://dx.doi.org/10.1139/y87-397.

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The prejunctional activities of S-3341 and clonidine have been studied in the transmural field-stimulated epididymal part of the rat vas deferens. Both S-3341 and clonidine inhibited these neuronally induced contractions. At high concentrations, these agonists induced spontaneous contractions in the preparation, which were abolished by 10−7 M prazosin. The inhibitory effects of S-3341 and clonidine were antagonized in a competitive manner by rauwolscine and were found not to be modified in a statistically significant manner by 10−7 M prazosin. The pA2 values of rauwolscine against S-3341 and c
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10

Busatto, Pedro A., and Aron Jurkiewicz. "Simultaneous measurement of contractile effects in the circular and longitudinal smooth muscle of the rat vas deferens by drugs perfused externally or via the lumen." British Journal of Pharmacology 85, no. 4 (1985): 737–46. http://dx.doi.org/10.1111/j.1476-5381.1985.tb11071.x.

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11

Bailey, S. K., and I. M. Davies. "The Effects of Tributyltin on Dogwhelks (Nucella Lapillus) From Scottish Coastal Waters." Journal of the Marine Biological Association of the United Kingdom 69, no. 2 (1989): 335–54. http://dx.doi.org/10.1017/s0025315400029453.

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The common dogwhelk (Nucella lapillus) is a dioecious species. However, on exposure to low concentrations (<1 ng I-1, Gibbs et al., 1987) of tributyltin (TBT) females develop certain male sexual characteristics, notably a penis and vas deferens. This phenomenon, first reported by Blaber (1970) in dogwhelks from the Plymouth area, and later termed 'imposex' (Smith, 1981), is now recognised as the most sensitive and straightforward way to identify contamination of coastal areas by TBT. The degree of imposex may be readily quantified as the relative penis size index (RPSI), which expresses the
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12

Yaris, E. "The effects of paroxetine on rat isolated vas deferens." Pharmacological Research 48, no. 4 (2003): 335–45. http://dx.doi.org/10.1016/s1043-6618(03)00157-9.

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13

Trachte, George J. "Angiotensin effects on vas deferens adrenergic and purinergic neurotransmission." European Journal of Pharmacology 146, no. 2-3 (1988): 261–69. http://dx.doi.org/10.1016/0014-2999(88)90301-9.

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14

Doxey, J. C., A. G. Roach, and J. Samuel. "Effects of desipramine on stimulation-induced contractions of the vas deferens of rats pretreated either chronically with desipramine or acutely with idazoxan." Clinical Science 68, s10 (1985): 155s—159s. http://dx.doi.org/10.1042/cs068s155.

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1. In the present studies the effects of desipramine on the functional sensitivity of the prejunctional α2-adrenoceptors of the vas deferens were studied in pithed rats; contractions of the tissue were evoked by electrical stimulation (6 Hz) of the spinal sympathetic outflow. 2. Twenty-four hours after a single dose of desipramine (10 mg/kg, intraperitoneally) the inhibitory dose-response curves to either UK 14 304 or desipramine itself did not differ significantly from those seen in control animals, whereas both were displaced significantly to the right after 15 days pretreatment with desipra
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15

Souza, Cláudio Fontes, Lúcia Garcez-do-Carmo, Isaltino Marcelo Conceição, Thalma Ariani Freitas, and Roberto Frussa-Filho. "Effects of long-term fluoxetine treatment on adrenergic plasticity in rat vas deferens." Brazilian Journal of Pharmaceutical Sciences 50, no. 4 (2014): 757–64. http://dx.doi.org/10.1590/s1984-82502014000400011.

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Chronic antidepressant administration increases neurotrophin levels in the central and peripheral nervous system, leading to an increase of neuronal sprouting, reestablishment of neural networks and neurotransmitter levels. Injured peripheral nerves regenerate at very slow rates. However, the recovery of the hypogastric nerve in rodents after injury is significantly improved with neurotrophin administration. Accordingly, our goal was to determine whether treatment with the antidepressant fluoxetine affects catecholamine levels and neuronal function, after surgical denervation of the rat vas de
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16

Veyssiere, G., Ch Jean-Faucher, M. Berger, and Cl Jean. "Evidence for reversible and irreversible biochemical defects in accessory sex organs and kidney of neonatally androgenized male mice." Acta Endocrinologica 121, no. 1 (1989): 121–28. http://dx.doi.org/10.1530/acta.0.1210121.

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Abstract. Studies were conducted to evaluate the effects of neonatal administration of supraphysiological doses of testosterone on the growth, hormone responsiveness, DNA and protein content, and protein profiles of the epididymis, vas deferens and seminal vesicles in adult mice. Results indicate that in androgenized males, testicular growth (DNA and protein content), circulating and organ androgen levels, and fertility were significantly depressed. The weights of the epididymis, vas deferens, seminal vesicle and kidney, but not that of the spleen, were significantly diminished subsequently to
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17

Medina, Pascual, Gloria Segarra, Rosa Ballester, et al. "Effects of antidepressants in adrenergic neurotransmission of human vas deferens." Urology 55, no. 4 (2000): 592–97. http://dx.doi.org/10.1016/s0090-4295(99)00535-x.

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18

Valenti, Gabriele, Emanuele Baldassarre, and Giovanni Torino. "Vas Deferens Obstruction Due to Fibrosis after Plug Hernioplasty." American Surgeon 72, no. 2 (2006): 137–38. http://dx.doi.org/10.1177/000313480607200208.

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The positioning of mesh and plug is routinely performed in hernioplasty, but knowledge about the long-term side effects of plug-induced fibrosis on the vas is incomplete. This is the first case of a documented fibrotic vas deferens obstruction resulting from compression of the plug that was in direct contact with the vas. During subsequent repair for a recurrent hernia, the cord and the plug appeared enveloped in dense fibrous tissue. Microscopy confirmed gross surgical findings. To reduce this morbidity, we suggest a cremaster sparing surgery, avoiding the positioning of bioprosthesis in dire
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19

Sciani, J. M. "Characterization of Bothrops jararaca snake venom effects on rat vas deferens." Journal of Venomous Animals and Toxins including Tropical Diseases 15, no. 4 (2009): 799–800. http://dx.doi.org/10.1590/s1678-91992009000400017.

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20

Pupo, André S. "Functional effects of castration on α1-adrenoceptors in rat vas deferens". European Journal of Pharmacology 351, № 2 (1998): 217–23. http://dx.doi.org/10.1016/s0014-2999(98)00315-x.

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21

Nagata, K., H. Saito, and N. Matsuki. "Effects of neurokinin A on Ca2+ mobilization in rat vas deferens." European Journal of Pharmacology 183, no. 6 (1990): 2401. http://dx.doi.org/10.1016/0014-2999(90)93969-w.

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22

Nasata, Koichi, Hiroshi Saito, and Norio Matsuki. "Effects of neurokinin A on Ca2+ mobilization in rat vas deferens." Japanese Journal of Pharmacology 52 (1990): 94. http://dx.doi.org/10.1016/s0021-5198(19)55109-5.

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23

Jang, Sun Ae, Oh Cheol Kwon, Jeoung Hee Ha, Kwang Youn Lee, and Won Joon Kim. "Effects of octreotide on the contractility of isolated rat vas deferens." Yeungnam University Journal of Medicine 10, no. 1 (1993): 144. http://dx.doi.org/10.12701/yujm.1993.10.1.144.

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24

Cunnanc, T. C., and R. Manchanda. "EFFECTS OF RESERPINE PRETREATMENT ON NEUROEFFECTOR TRANSMISSION IN THE VAS DEFERENS." Clinical and Experimental Pharmacology and Physiology 16, no. 6 (1989): 451–55. http://dx.doi.org/10.1111/j.1440-1681.1989.tb01586.x.

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25

Barun, Sureyya, Ismail Mert Vural, Ergin Dilekoz, Zeynep Sevim Ercan, and Yusuf Sarioglu. "EFFECTS OF CANNABINOID RECEPTOR ACTIVATION ON RABBIT BISECTED VAS DEFERENS STRIPS." Clinical and Experimental Pharmacology and Physiology 32, no. 9 (2005): 702–7. http://dx.doi.org/10.1111/j.1440-1681.2005.04261.x.

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26

SUZUKI, Nagao, and Yasuo GOMI. "Effects of mazindol on the contractions in the rat vas deferens." Journal of Pharmacobio-Dynamics 13, no. 11 (1990): 666–71. http://dx.doi.org/10.1248/bpb1978.13.666.

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27

Turunc, Tahsin, Yildirim Bayazit, Figen Doran, Nebil Bal, and Saban Doran. "Effects of Vas Deferens Obstruction on Cajal-Like Cells in Rats." Urologia Internationalis 83, no. 1 (2009): 86–91. http://dx.doi.org/10.1159/000224875.

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28

ABEL, P. W., A. W. FOX, and K. P. MINNEMAN. "EFFECTS OF ISOXUPRINE AND NYLIDRIN ON ADRENORECEPTORS IN RAT VAS DEFERENS." Journal of Autonomic Pharmacology 5, no. 3 (1985): 213–20. http://dx.doi.org/10.1111/j.1474-8673.1985.tb00122.x.

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29

PUBILL, D., A. M. CANUDAS, M. PALLÀS, et al. "Assessment of the Adrenergic Effects of Orphenadrine in Rat Vas Deferens." Journal of Pharmacy and Pharmacology 51, no. 3 (1999): 307–12. http://dx.doi.org/10.1211/0022357991772303.

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30

Miranda, Hugo F., Wayne W. Wolstenholme, Gil M. Moreu, and Pedro A. Santiago. "Effects of haloperidol on neurotransmitter activity in the rat vas deferens." General Pharmacology: The Vascular System 19, no. 1 (1988): 123–27. http://dx.doi.org/10.1016/0306-3623(88)90017-1.

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31

Queiroz-Neto, Antonio, Maria Isabel Mataqueiro, and Gustavo Ballejo. "Effects of lithium and myoinositol on the rat bisected vas deferens." General Pharmacology: The Vascular System 26, no. 8 (1995): 1735–39. http://dx.doi.org/10.1016/0306-3623(95)00069-0.

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32

Zoubek, J., G. T. Somogyi, and W. C. De Groat. "A comparison of inhibitory effects of neuropeptide Y on rat urinary bladder, urethra, and vas deferens." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 265, no. 3 (1993): R537—R543. http://dx.doi.org/10.1152/ajpregu.1993.265.3.r537.

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The effects of human and porcine neuropeptide Y (NPY) on electrically induced contractions of smooth muscle strips from rat urinary bladder, urethra, and vas deferens were investigated. NPY (10 nM-10 microM) inhibited to the contractile response in all preparations. The magnitude of inhibition by NPY was dependent on frequency of stimulation in each organ, the inhibition being in general much greater (80-100%) at low frequencies (2-5 Hz) than at high frequencies (30-40% at 10-100 Hz). The vas deferens and urethra exhibited nearly maximal inhibition (90-100%) over a broader range of stimulus fr
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33

Abidli, Sami, Youssef Lahbib, and Najoua Trigui El Menif. "Effects of TBT on the imposex development, reproduction and mortality in Hexaplex trunculus (Gastropoda: Muricidae)." Journal of the Marine Biological Association of the United Kingdom 89, no. 1 (2009): 139–46. http://dx.doi.org/10.1017/s0025315408002282.

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Tributyltin (TBT) exposure experiments at 5 and 50 ng l−1 concentrations were carried out in the laboratory on female Hexaplex trunculus collected during the reproductive season from a site weakly-affected by imposex (12.1%). The imposex intensity estimated by the imposex incidence or frequency (I%), the average length of the vas deferens (VDL), the average length of female penis (FPL) and the vas deferens sequence index (VDSI) showed significant variation with TBT concentration. The number of spawning females decreased with TBT concentration. TBT had no effect on the number of egg-capsules la
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34

Manchanda, R., and K. Venkateswarlu. "Effects of heptanol on electrical activity in the guinea-pig vas deferens." British Journal of Pharmacology 120, no. 3 (1997): 367–70. http://dx.doi.org/10.1038/sj.bjp.0700900.

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35

Holmquist, F., H. Hedlund, and K. E. Andersson. "Pre- and postjunctional effects of some prostanoids in human isolated vas deferens." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 260, no. 4 (1991): R792—R797. http://dx.doi.org/10.1152/ajpregu.1991.260.4.r792.

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The effects of prostaglandin (PG) E1, PGE2, the thromboxane A2 analogue U-44069, and the prostacyclin derivative iloprost were studied on isometric contractions induced by norepinephrine (NE) and by electrical field stimulation of nerves in isolated preparations of the human vas deferens. The effects of these agents on the electrically induced release of 3H from preparations preincubated with [3H]NE were also investigated. PGE1 and PGE2 inhibited the electrically induced contractions concentration dependently. U-44069 augmented the contractions without affecting baseline tension, and in prepar
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36

Long, Clive J., and Trevor W. Stone. "The effects of adenosine on receptor sensitivity in the rat vas deferens." European Journal of Pharmacology 132, no. 1 (1986): 11–19. http://dx.doi.org/10.1016/0014-2999(86)90003-8.

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37

Kaya, T., Y. Sarioglu, T. Utkan, C. Mimaroglu, and K. Yildirim. "Effects of propofol on symphatetic neurotransmission in the isolated rat vas deferens." Pharmacological Research 31 (January 1995): 370. http://dx.doi.org/10.1016/1043-6618(95)87741-x.

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38

Rae, Giles A., and João B. Calixto. "Effects of endothelins on nerve-mediated contractions of the mouse vas deferens." Life Sciences 47, no. 17 (1990): PL83—PL89. http://dx.doi.org/10.1016/0024-3205(90)90191-s.

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39

Ari, Gil, and John P. M. Finberg. "Effects of clorgyline on the release of noradrenaline from rat vas deferens." European Journal of Pharmacology 219, no. 1 (1992): 89–96. http://dx.doi.org/10.1016/0014-2999(92)90584-q.

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40

Harris, J. B., and A. M. Surprenant. "Effects of notexin on neuromuscular transmission in the guinea pig vas deferens." Toxicon 28, no. 4 (1990): 393–401. http://dx.doi.org/10.1016/0041-0101(90)90077-k.

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41

Demirtola, Arzu, I. Onur Ozen, Gokce S. Ozturk, et al. "The effects of varicocele and its surgical correction on vas deferens motility." Pediatric Surgery International 24, no. 3 (2007): 319–23. http://dx.doi.org/10.1007/s00383-007-2074-8.

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42

URABE, Masanobu, Hiromu KAWASAKI, and Koichiro TAKASAKI. "Effects of Methamphetamine on the Twitch Response in the Rat Isolated Vas Deferens." Japanese Journal of Pharmacology 45, no. 3 (1987): 357–64. http://dx.doi.org/10.1016/s0021-5198(19)43391-x.

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43

Kaschube, Michael, and Helmut Brasch. "Pre- and postjunctional effects of N-ethylmaleimide in the isolated mouse vas deferens." European Journal of Pharmacology 178, no. 2 (1990): 151–59. http://dx.doi.org/10.1016/0014-2999(90)90470-q.

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44

Forsyth, K. M., K. Shinozuka, R. A. Bjur, and D. P. Westfall. "The prejunctional effects of purine agonists and antagonists in the rat vas deferens." European Journal of Pharmacology 183, no. 6 (1990): 2140. http://dx.doi.org/10.1016/0014-2999(90)93662-a.

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45

Sugioka, Toshihiko, Tomohisa Ishikawa, Yutaka Matsuoka, Haruhisa Uchida, Tsutomu Uruno, and Kazuhiko Kubota. "Effects of non-catecholic phenylethylamine derivatives on the isolated vas deferens of rats." Japanese Journal of Pharmacology 40 (1986): 117. http://dx.doi.org/10.1016/s0021-5198(19)59105-3.

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46

Andersson, K. E., M. Fovaeus, H. Hedlund, F. Holmquist, and S. Lundin. "Immunoreactive Arginine Vasopressin (AVP) and Effects of Avp in the Human Vas Deferens." Journal of Urology 140, no. 5 Part 1 (1988): 1054–57. http://dx.doi.org/10.1016/s0022-5347(17)41925-2.

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47

Castor, Lidyane R. G., Eunice Oba, and Oduvaldo C. M. Pereira. "Effects of swimming and nandrolone decanoate treatment on vas deferens response to norepinephrine." Life Sciences 85, no. 13-14 (2009): 541–45. http://dx.doi.org/10.1016/j.lfs.2009.08.009.

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48

Dixon, J. S., C. J. Gilpin, S. A. Gilpin, J. A. Gosling, and J. F. B. Grant. "The Effects of Vasectomy on the Autonomic Innervation of the Human Vas Deferens." Journal of Urology 137, no. 5 (1987): 1014–16. http://dx.doi.org/10.1016/s0022-5347(17)44349-7.

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49

HOYLE, CHARLES H. V., ALESSANDRA POSTORINO, and GEOFFREY BURNSTOCK. "Pre- and Postjunctional Effects of Diadenosine Polyphosphates in the Guinea-pig Vas Deferens." Journal of Pharmacy and Pharmacology 47, no. 11 (1995): 926–31. http://dx.doi.org/10.1111/j.2042-7158.1995.tb03272.x.

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50

Lara, H., and W. Bastos-Ramos. "Glutamate and kainate effects on the noradrenergic neurons innervating the rat vas deferens." Journal of Neuroscience Research 19, no. 2 (1988): 239–44. http://dx.doi.org/10.1002/jnr.490190209.

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