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Relevant bibliographies by topics / Drug Interactions. Metabolic Detoxication, Drug. Phenytoin

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Journal articles
Dissertations / Theses

Academic literature on the topic 'Drug Interactions. Metabolic Detoxication, Drug. Phenytoin'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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Journal articles on the topic "Drug Interactions. Metabolic Detoxication, Drug. Phenytoin"

1

Vaishnavi S, Balaji S, Ramesh M, Mothi S N, Swamy V H T, and Srirama B R. "Drug – Drug Interactions Between Newer Anti- Retroviral Drugs And Anti Epileptics - A Review." International Journal of Research in Pharmaceutical Sciences 11, no. 3 (2020): 2963–67. http://dx.doi.org/10.26452/ijrps.v11i3.2386.

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Drug – Drug Interactions (DDIs) are the leading cause of drug toxicity and emergence of drug resistance, ultimately leading to increased burden in People Living with Human Immunodeficiency Virus (PLHIV). On an average 55 % of people on Anti Retroviral Therapy (ARVs) are co-administered with Anti Epileptic Drugs (AEDs). The introduction of newer anti-retroviral drugs such as dolutegravir, bictegravir, emtricitabine, doravirine are proven to have less side effects, high tolerability and effective decrease in the viral load, but the risk of DDIs still stands to be high. This review briefly descri

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2

Anderson, Gail D. "A Mechanistic Approach to Antiepileptic Drug Interactions." Annals of Pharmacotherapy 32, no. 5 (1998): 554–63. http://dx.doi.org/10.1345/aph.17332.

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OBJECTIVE: To describe the primary types of antiepileptic drug (AED) interactions by using a mechanistic approach. DATA SOURCES: A literature search was performed using MEDLINE and bibliographies of recent review articles and published abstracts. DISCUSSION: AEDs are associated with a wide range of drug interactions, including hepatic enzyme induction and inhibition and protein-binding displacement. Hepatic induction by AEDs affects the metabolism of a limited number of drugs with low therapeutic indices. Anticipation of induction interactions and careful clinical monitoring may alleviate pote

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Faigle, Johann W., and Guenter P. Menge. "Metabolic Characteristics of Oxcarbazepine (®Trileptal) and their Beneficial Implications for Enzyme Induction and Drug Interactions." Behavioural Neurology 3, no. 1 (1990): 21–30. http://dx.doi.org/10.1155/1990/917164.

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Hepatic oxygenases of the cytochrome P-450 family play a major role in the clearance of various anti-epileptic drugs. These enzymes are susceptible both to induction and to inhibition. Phenytoin, carbamazepine (CBZ), primidone, and phenobarbitone, for instance, are potent enzyme inducers. Other drugs, such as chloramphenicol, propoxyphene, verapamil, and viloxazine, inhibit cytochrome P-450. Pharmacokinetic behaviour is thus often altered, especially in combined medication, so that the dosage has to be re-adjusted if an optimum therapeutic outcome is to be ensured. Oxcarbazepine (OXC) is a ket

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Leung, Simon, and Mara Poulakos. "Drug Interaction Profile of Posaconazole." Internet Journal of Allied Health Sciences and Practice, 2008. http://dx.doi.org/10.46743/1540-580x/2008.1196.

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Adverse drug events resulting from drug-drug interactions may lead to emergency department visits, hospitalizations, prolonged length of stays, increased medical care costs, and death. Despite the efforts of research, clinical studies, and active reporting to identify and explain these drug interaction pathways, clinicians are often unaware of such drug-drug interactions. Therefore, it is imperative for pharmacists to identify these potential drug-drug interactions and notify the clinicians as well as the patients so that appropriate safety measures and monitoring methods are implemented. Spec

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Dissertations / Theses on the topic "Drug Interactions. Metabolic Detoxication, Drug. Phenytoin"

1

Bajpai, Manoj. "Metabolic isozymes of phenytoin and their roles in its drug interactions /." Thesis, Connect to this title online; UW restricted, 1996. http://hdl.handle.net/1773/7961.

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