Academic literature on the topic 'Drug-Nutraceutical Interactions'

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Journal articles on the topic "Drug-Nutraceutical Interactions"

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Endriastuti, Nialiana Endah, Masita Wulandari Suryoputri, Dewi Latifatul Ilma, and Tunggul Adi Purwonugroho. "The potential interaction between antiepileptic drugs and nutraceuticals used in pediatrics with epilepsy." Acta Pharmaciae Indonesia : Acta Pharm Indo 10, no. 1 (2022): 4352. http://dx.doi.org/10.20884/1.api.2022.10.1.4352.

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Background: The trend of using nutraceuticals in Indonesia increases every year. This study aims to describe nutraceuticals consumed in pediatrics with epilepsy as additional antiepileptic therapy and analyze their potential drug interactions.
 Methods: This research was a cross-sectional study with total sampling method which was carried out in the period of June to July 2020. Inclusion criteria were children with epilepsy aged 0-17 years who were members of the Indonesian Epilepsy Community, had a doctor's diagnosis of epilepsy, received oral antiepileptic medication, and took nutraceut
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Spagnuolo, Paul. "Interactions Between Nutraceutical Supplements and Standard Acute Myeloid Leukemia Chemotherapeutics." Journal of Pharmacy & Pharmaceutical Sciences 18, no. 4 (2015): 339. http://dx.doi.org/10.18433/j3m30k.

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PURPOSE: Concomitant use of nutraceuticals with chemotherapy is very common. Cancer patients self-medicate to relieve the side effects associated with chemotherapy, improve disease outcome and to regain control of their medical care. However, there is limited empirical evidence on potential drug-nutraceutical interactions and their resulting effect on chemotherapy efficacy. METHOD: To investigate drug-nutraceutical interactions we created and screened a library of commonly used nutraceuticals for their modulatory effects on the activity of cytarabine and daunorubicin, two primary chemotherapeu
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Garrido, Camila Caro, Marie Vandooren, Koen Robeyns, Damien P. Debecker, Patricia Luis, and Tom Leyssens. "Combining a Drug and a Nutraceutical: A New Cocrystal of Praziquantel and Curcumin." Crystals 14, no. 2 (2024): 181. http://dx.doi.org/10.3390/cryst14020181.

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This study explores the co-crystallization between the drug praziquantel (PZQ) and the nutraceutical curcumin (CU). The investigation revealed two novel solid forms: a cocrystal solvate with ethyl acetate and a non-solvated cocrystal. This novel drug–nutraceutical cocrystal is a praziquantel–curcumin (2:1) cocrystal. The cocrystal solvate has ethyl acetate molecules occupying the voids with minimal interactions within the crystal lattice. The application of heat treatment induces solvent removal and prompts the transition to the non-solvated cocrystal, as highlighted by variable-temperature X-
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Blaze, Jessica. "A Comparison of Current Regulatory Frameworks for Nutraceuticals in Australia, Canada, Japan, and the United States." INNOVATIONS in pharmacy 12, no. 2 (2021): 8. http://dx.doi.org/10.24926/iip.v12i2.3694.

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The nutraceutical market is growing and the demand for products is increasing. Consumers are looking for cheaper alternatives to prescription medications as well as health products to supplement their dietary intake on a regular basis. Many countries classify these products into different categories based on their health claims. The purpose of this review is to compare and contrast the differences of regulatory frameworks in countries of similar status in regard to nutraceutical products: vitamins, minerals, herbal supplements, and probiotics. This review also takes into consideration the aspe
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Jannati, Shirin, Adiba Patel, Rajashree Patnaik, and Yajnavalka Banerjee. "Oleocanthal as a Multifunctional Anti-Cancer Agent: Mechanistic Insights, Advanced Delivery Strategies, and Synergies for Precision Oncology." International Journal of Molecular Sciences 26, no. 12 (2025): 5521. https://doi.org/10.3390/ijms26125521.

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Oleocanthal (OC), a secoiridoid phenolic compound exclusive to extra virgin olive oil (EVOO), has emerged as a promising nutraceutical with multifaceted anti-cancer properties. Despite its well-characterized anti-inflammatory and antioxidant effects, the mechanistic breadth and translational potential of OC in oncology remain underexplored and fragmented across the literature. This comprehensive review synthesizes and critically analyzes recent advances in the molecular, pharmacological, and translational landscape of OC’s anti-cancer activities, providing an integrative framework to bridge pr
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Calvani, Maura, Amada Pasha, and Claudio Favre. "Nutraceutical Boom in Cancer: Inside the Labyrinth of Reactive Oxygen Species." International Journal of Molecular Sciences 21, no. 6 (2020): 1936. http://dx.doi.org/10.3390/ijms21061936.

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In recent years, epidemiological studies have shown that food is a very powerful means for maintaining a state of well-being and for health prevention. Many degenerative, autoimmune and neoplastic diseases are related to nutrition and the nutrient–organism interaction could define the balance between health and disease. Nutrients and dietary components influence epigenetic phenomena and modify drugs response; therefore, these food–host interactions can influence the individual predisposition to disease and its potential therapeutic response. Do nutraceuticals have positive or negative effects
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Davis, Mellar P., Bertrand Behm, Zankhana Mehta, and Carlos Fernandez. "The Potential Benefits of Palmitoylethanolamide in Palliation: A Qualitative Systematic Review." American Journal of Hospice and Palliative Medicine® 36, no. 12 (2019): 1134–54. http://dx.doi.org/10.1177/1049909119850807.

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Palmitoylethanolamide (PEA) is a nutraceutical endocannabinoid that was retrospectively discovered in egg yolks. Feeding poor children with known streptococcal infections prevented rheumatic fever. Subsequently, it was found to alter the course of influenza. Unfortunately, there is little known about its pharmacokinetics. Palmitoylethanolamide targets nonclassical cannabinoid receptors rather than CB1 and CB2 receptors. Palmitoylethanolamide will only indirectly activate classical cannabinoid receptors by an entourage effect. There are a significant number of prospective and randomized trials
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Puri, Vivek, Manju Nagpal, Inderbir Singh, et al. "A Comprehensive Review on Nutraceuticals: Therapy Support and Formulation Challenges." Nutrients 14, no. 21 (2022): 4637. http://dx.doi.org/10.3390/nu14214637.

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Nutraceuticals are the nourishing components (hybrid of nutrition and pharmaceuticals) that are biologically active and possess capability for maintaining optimal health and benefits. These products play a significant role in human health care and its endurance, most importantly for the future therapeutic development. Nutraceuticals have received recognition due to their nutritional benefits along with therapeutic effects and safety profile. Nutraceuticals are globally growing in the field of services such as health care promotion, disease reduction, etc. Various drug nutraceutical interaction
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Persiani, S., F. Sala, C. Manzotti, et al. "An oral cocktail study on potential drug interactions of a proprietary nutraceutical combination containing berberine and monacolin in healthy volunteers." Atherosclerosis 235, no. 2 (2014): e297-e298. http://dx.doi.org/10.1016/j.atherosclerosis.2014.05.896.

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Prasad, Sakhare* Kailas Jadhao Kailash Biyani. "Classification of Nutraceuticals: From Traditional Roots to Modern Innovations." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 1431–38. https://doi.org/10.5281/zenodo.15379417.

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In recent years, the increased availability of a wide variety of processed and unhealthy food products has prompted major concerns about their harmful health, environmental, and social implications. The excessive use of such foods has been related to a rise in chronic diseases, including diabetes, obesity, cancer, osteoporosis, and numerous allergy problems. In response, nutraceuticals have developed as viable solutions to improve health and enhance immunity. These bioactive chemicals, derived from food sources, have a key role in preventing disease and maintaining normal physiological activit
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Book chapters on the topic "Drug-Nutraceutical Interactions"

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Üçer, Oktay, and Özlem Tokuşoğlu. "Specific Cancer Clinical Studies and Drug Interactions on Nutraceutical Fruit and Plant Powders." In Food By-Product Based Functional Food Powders. CRC Press, 2018. http://dx.doi.org/10.1201/9781315373607-8.

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Godad, Angel, Alveera Ansari, Nirav Bhatia, Aaliya Ali, Sandip Zine, and Gaurav Doshi. "Drug nutraceutical interactions." In Industrial Application of Functional Foods, Ingredients and Nutraceuticals. Elsevier, 2023. http://dx.doi.org/10.1016/b978-0-12-824312-1.00020-0.

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Dias-Souza, Marcus Vinícius, and Renan Martins dos Santos. "Phytonutrients of Nutraceutical Importance." In Pharmaceutical Sciences. IGI Global, 2017. http://dx.doi.org/10.4018/978-1-5225-1762-7.ch020.

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Phytotherapy re-emerged in the latest years as a healing system accepted and spread worldwide, and different molecules have been investigated due to their benefits to health. Nutraceutical formulations, which allow the intake of phytonutrients (generally in low levels in plant food) in concentrations that are enough to achieve the desired outcomes, represent feasible alternatives to improve general health and to prevent and treat varied diseases. Notwithstanding the incompleteness of an evidence-based clinical use of nutraceuticals, many questions remain unanswered regarding their global effec
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Dias-Souza, Marcus Vinícius, and Renan Martins dos Santos. "Phytonutrients of Nutraceutical Importance." In Examining the Development, Regulation, and Consumption of Functional Foods. IGI Global, 2017. http://dx.doi.org/10.4018/978-1-5225-0607-2.ch003.

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Phytotherapy re-emerged in the latest years as a healing system accepted and spread worldwide, and different molecules have been investigated due to their benefits to health. Nutraceutical formulations, which allow the intake of phytonutrients (generally in low levels in plant food) in concentrations that are enough to achieve the desired outcomes, represent feasible alternatives to improve general health and to prevent and treat varied diseases. Notwithstanding the incompleteness of an evidence-based clinical use of nutraceuticals, many questions remain unanswered regarding their global effec
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Anthony, Josephine, Vijaya Raghavan Rangamaran, Kumar T. Shivasankarasubbiah, Dharani Gopal, and Kirubagaran Ramalingam. "Applications of Molecular Docking." In Advances in Medical Technologies and Clinical Practice. IGI Global, 2016. http://dx.doi.org/10.4018/978-1-5225-0362-0.ch011.

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Computational tools have extended their reach into different realms of scientific research. Often coupled with molecular dynamics simulation, docking provides comprehensive insight into molecular mechanisms of biological processes. Influence of molecular docking is highly experienced in the field of structure based drug discovery, wherein docking is vital in validating novel lead compounds. The significance of molecular docking is also understood in several environmental and industrial research, in order to untangle the interactions among macromolecules of non-medical interest. Various process
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