Academic literature on the topic 'Drug physico-chemical compatibility'

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Journal articles on the topic "Drug physico-chemical compatibility"

1

Sharma, N., and T. Sinderpal. "Sterculia Gum: Chemical Structure, Composition and Physico-Chemical Properties." Asian Journal of Chemistry 32, no. 1 (2019): 1–8. http://dx.doi.org/10.14233/ajchem.2020.22283.

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Physico-chemical properties are crucial characteristics of hydrocolloids as they decide the applicability of them. Rheology of system, flow behaviour and mechanical properties make hydrocolloids suitable for food industry. Modification of consistency or texture properties of functional polymers also controls their sensory characteristics, thereby they become significant essences such as thickener, gelling agents, foaming agent, texture modifier, viscosifier, emulsifier, stabilizer and binder. Industrial and pharmaceutical applications are also controlled by some suitable physico-chemical prope
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Sharma, Shyam Bihari, Suman Jain, and K. Ganesan. "Preformulation Studies of Pralidoxime Chloride for Formulation Development of Microspheres." Journal of Drug Delivery and Therapeutics 9, no. 4-s (2019): 338–42. http://dx.doi.org/10.22270/jddt.v9i4-s.3336.

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Microspheres are one of the novel drug delivery system which possess several applications and are made up of assorted polymers. Microspheres can be defined as solid, approximately spherical particles ranging in size from 1 to 1000 μm range in diameter having a core of drug and entirely outer layers of polymers as coating material. They are made up of polymeric, waxy or other protective materials i.e. biodegradable synthetic polymer and modified natural products such as starches, gums, proteins, fats and waxes. Preformulation is a group of studies that focus on the physicochemical properties of
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3

Tiwari, Sandip Prasad, and Gali Vidyasagar. "Identification, Characterization and Drug-Excipient Compatibility of Diltiazem Hydrochloride by Physico-Chemical Techniques." UK Journal of Pharmaceutical Biosciences 2, no. 5 (2014): 49. http://dx.doi.org/10.20510/ukjpb/2/i5/91134.

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4

Bruni, Giovanna, Vittorio Berbenni, Chiara Milanese, Alessandro Girella, and Amedeo Marini. "Drug-excipient compatibility studies in binary and ternary mixtures by physico-chemical techniques." Journal of Thermal Analysis and Calorimetry 102, no. 1 (2009): 193–201. http://dx.doi.org/10.1007/s10973-009-0382-z.

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5

Vivekanandan S, Raghunandan Reddy K, and Venkatesan P. "Preformulation characterization towards design and development of dexibuprofen loaded nanoparticles." International Journal of Research in Pharmaceutical Sciences 11, no. 4 (2020): 8138–45. http://dx.doi.org/10.26452/ijrps.v11i4.4892.

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The intention of the current study was to investigate the Physico-chemical characteristics of Dexibuprofen loaded nanoparticles. Dexibuprofen is an NSAID - non-steroidal anti-inflammatory drug intended for the treatment of rheumatoid arthritis related symptoms. In current market trends, the tablets and capsule dosage forms captures major market contribution. A systematic evaluation of physico chemical characteristics of the drug powder, it’s characteristics was performed as a basic step at the start of formulation development of the dosage form. The formulation development approach is decided
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6

Mohamed, Amir Ibrahim, Amal Abd-Elaal El-Khamery, Mohamed Ismail Herry, and Alaa Ibrahim Mohamed. "Compatibility Determination of Drug-Polymer, Drug-Excipient & Drug-Intravenous Admixtures Using Chemometric-assisted UVspectrophotometry." Current Pharmaceutical Analysis 16, no. 2 (2020): 125–42. http://dx.doi.org/10.2174/1573412914666181011142351.

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Purpose: A new multivariate chemometric approach was developed for fast and economic compatibility determinations of ranitidine hydrochloride (as model drug) with certain pharmaceutical; polymers (Alginate & Chitosan), excipient (Lactose) and intravenous fluids (Dextrose, Ringer & Dextrose/ Ringer). Binary mixtures of the drug and each item were prepared and investigated by chemometric- assisted UV- spectrophotometry as well as by HPLC reference method. Methods: Five drug concentration levels (0.004-0.025mg/ml) of test-mixtures were used and the average drug recovery percent after two
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Yadav, RK, Satyam Prakash, K. Yadav, NK Yadav, and M. Mostafa. "Physico-chemical evaluation of Gastroretentive Ranitidine Hydrochloride: An Anti-Ulcer Drug." Janaki Medical College Journal of Medical Science 3, no. 2 (2016): 4–12. http://dx.doi.org/10.3126/jmcjms.v3i2.16075.

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Background and Objectives: The prevention and treatment of peptic ulcers has become an important challenge in the current medicine world. Modern progress in novel drug delivery system aims to improve the efficacy of the drug molecule by formulating a dosage form of RHCL. One of the most feasible approaches for achieving a prolonged and predictable drug delivery profile in GI tract is to control the gastric residence time. Therefore, a multi-unit gastro retentive dosage form of RHCL capable of floating on simulated gastric fluid for more than 12 hours was formulated and evaluated.Materials and
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Kamin, Wolfgang, Astrid Schwabe, and Irene Krämer. "Inhalation solutions – which one are allowed to be mixed? Physico-chemical compatibility of drug solutions in nebulizers." Journal of Cystic Fibrosis 5, no. 4 (2006): 205–13. http://dx.doi.org/10.1016/j.jcf.2006.03.007.

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9

Kamin, Wolfgang, Frank Erdnüss, and Irene Krämer. "Inhalation solutions — Which ones may be mixed? Physico-chemical compatibility of drug solutions in nebulizers — Update 2013." Journal of Cystic Fibrosis 13, no. 3 (2014): 243–50. http://dx.doi.org/10.1016/j.jcf.2013.09.006.

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10

Ronowicz-Pilarczyk, Joanna. "Compatibility Study of Ketoprofen With Selected Excipients Used in Solid Dosage Forms: Experimental Design Approach." Acta Poloniae Pharmaceutica - Drug Research 80, no. 5 (2023): 717–22. http://dx.doi.org/10.32383/appdr/172622.

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A good understanding of the physico-chemical characteristics of a drug substance and excipients is necessary to obtain a safe and effective drug dosage form. Based on the current recommendations of the regulatory agencies (EMA, FDA) regarding the implementation of the Quality by Design concept at the drug product development stage, this article is focused on the application of the experimental design approach at the preformulation studies. The purpose of this work was the implementation of experimental design methodology in a compatibility study between ketoprofen (non-steroidal anti-inflammat
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