Academic literature on the topic 'Drug repurp'

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Journal articles on the topic "Drug repurp"

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Sakshi, Kaushik* Priyal Jain. "Drug Repurposing an Effective Tool in Modern Drug Discovery." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 2652–56. https://doi.org/10.5281/zenodo.15432771.

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Drug repurposing is using an existing drug for a new treatment that was not indicated before. It has received immense attention during theCOVID-19 pandemic emergency. Drug repurposing has become the need of time to fasten the drug discovery process and find quickersolutionsto the over- exerted healthcare scenario and drug needs. Drug repurposing involve side notifying the drug, evaluatingits efficiency using preclinical models, and proceeding to phase II clinical trials. Identification of the drug candidate can be made through computational and experimental approaches. This approach usually ut
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Alshammari, Aiyad. "التقرير العالمي للمخدِّرات 2020". Security Policy Paper 2, № 1 (2021): 1–7. http://dx.doi.org/10.26735/yzwc2010.

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معالجة مشكلة المخدرات العالمية تتطلب تنفيذ سياسة متعلقة بالمخدرات بالتوازي مع تنفيذ خطط أوسع بشأن التنمية المستدامة والأمن وحقوق الإنسان. توسيع نطاق التدخلات العلاجية في علاج الاضطرابات الناشئة عن تعاطي المخدرات، وإدماج تلك التدخلات في نظام الرعاية الصحية لكل بلد. إتاحة الفرصة لنظام العدالة الجنائية في اختيار العلاج كعقوبة بديلة للسجن خصوصاً للمرأة. التي ارتكبت مخالفات بسيطة وتعاني من اضطرابات ناجمة عن تعاطي المخدرات.
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Santoki, Hirva S., Sapna D. Gupta, Shikha V. Sood, and Supriya D. Malhotra. "Drug-drug interactions presenting as Bradyarrhythmia and Hyperkalaemia: A Case Report." Journal of Pharmacovigilance and Drug Research 3, no. 4 (2022): 32–34. http://dx.doi.org/10.53411/jpadr.2022.3.4.6.

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S*, Desai. "Voriconazole (API): Global Market Growth Study Report." Bioequivalence & Bioavailability International Journal 8, no. 2 (2024): 1–6. http://dx.doi.org/10.23880/beba-16000238.

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Voriconazole API (active pharmaceutical ingredient) a thermolabile antifungal drug developed in 1980’s -a triazole class of drugs successfully surpassed the antifungal drugs having huge demand in market sales globally for its applications to treat severe fungal/yeast infections. The market growth involves its evolution of product in terms of innovation & technologies to withstand the competitiveness in aspect of new entry of drug, suppliers and buyers. The voriconazole drug surpassed USD 10 million dollars in 2023 within three years starting in the year 2020. the market report analysis col
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Boffito, Marta, Edward Acosta, David Burger, et al. "Therapeutic Drug Monitoring and Drug–Drug Interactions Involving Antiretroviral Drugs." Antiviral Therapy 10, no. 4 (2005): 469–77. http://dx.doi.org/10.1177/135965350501000413.

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The consensus of current international guidelines for the treatment of HIV infection is that data on therapeutic drug monitoring (TDM) of non-nucleoside reverse transcriptase inhibitors (NNRTIs) and protease inhibitors (PIs) provide a framework for the implementation of TDM in certain defined scenarios in clinical practice. However, the utility of TDM is considered to be on an individual basis until more data are obtained from large clinical trials showing the benefit of TDM. In April 2004, a panel of experts met for the second time in Rome, Italy. This was following the inaugural meeting in P
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Ekama, Sabdat Ozichu, David Ayoola Oladele, Adesola Zaidat Musa, Ebiere Clara Herbertson, Agatha Nkiru David, and Oliver Chukwujekwu Ezechi. "The effect of number of pills and dosing frequency on antiretroviral drug adherence: An assessment using two adherence monitoring measures." World Journal of Advanced Research and Reviews 14, no. 2 (2022): 253–60. https://doi.org/10.5281/zenodo.7297921.

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<strong>Background</strong>: Strict adherence requirement to antiretroviral drugs remains a key determinant of successful treatment outcome. Drug regimen complexity has been identified as a factor that discourages adherence to antiretroviral therapy. Several measures are available to assess drug adherence each with its strengths and weaknesses. Only few of these measures are cost effective and can be used in resource limited settings. <strong>Objective:&nbsp;</strong>To determine the effect of number of pills, dosing frequency, and concomitant drugs on adherence to antiretroviral drug therapy.
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胡家瑄, 胡家瑄, 王思翰 王思翰, 張博鈞 Szu-Han Wang та 郭彥彬 Po-Chun Chang. "藥物性牙齦增生:案例報告". 臺灣牙周病醫學會雜誌 27, № 2 (2022): 188–201. http://dx.doi.org/10.53106/102799622022092702006.

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Muhamed, Khaled. "تقرير المخدرات العالمي (2020): المخدرات النفسانية الجديدة". Security Policy Paper 2, № 2 (2021): 01–10. http://dx.doi.org/10.26735/tyio8607.

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洪麗期, 洪麗期, 謝明鴻 謝明鴻, 顏啟華 顏啟華 та 張正辰 Chi-Hua Yen. "疑似津普速引起之藥物熱:病例報告". 台灣家庭醫學雜誌 33, № 1 (2023): 053–58. http://dx.doi.org/10.53106/168232812023033301006.

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&lt;p&gt;藥物熱,指的是使用藥物後直接或間接引起的發燒,之前的文獻中對藥物熱相關的風險因子與臨床表現,沒有一致的描述。而津普速(olanzapine)是一種非典型抗精神藥物,主要用於治療思覺失調症及雙極性情感疾患,常見的副作用包括代謝症候群、嗜睡等等,發燒的發生機率極低,少於千分之一。&lt;/p&gt; &lt;p&gt;本篇個案報告為一位59歲女性在使用津普速後,發生發燒的現象,在排除可能原因後,推斷為罕見的津普速相關的藥物熱,在停用藥物之後發燒即緩解。在本篇個案報告中,我們統整了過去相關的文獻,試圖描繪出津普速引起之藥物熱的臨床特徵,討論可能的風險因子。希望藉此個案報告,讓基層醫師在鑑別診斷多重用藥病人的發燒時,能想到可能是罕見但能夠立即處理的津普速相關的藥物熱。&lt;/p&gt; &lt;p&gt;&amp;nbsp;&lt;/p&gt;&lt;p&gt;Drug fever refers to a febrile response with the administration of a drug in the absence of underlying conditions responsible for the fever and will disappear once the offending drug is discontinued. There is
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Naikwadi, Shagupta A., and Rupali B. Jadhav. "Nimesulide induced Stevens Johnson Syndrome: a case report." International Journal of Basic & Clinical Pharmacology 6, no. 8 (2017): 2094. http://dx.doi.org/10.18203/2319-2003.ijbcp20173303.

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Adverse drug reactions to the prescribed medicines are the major obstacles in continuation of drug treatment. Stevens- Johnson Syndrome (SJS) is a severe, episodic, acute mucocutaneous reaction which is most commonly elicited by drugs and occasionally by infections. Common drugs associated with SJS are sulphonamide antibiotics, anticonvulsants, non- steroidal anti-inflammatory drugs (NSAIDS) and allopurinol. Nimesulide is an NSAID with analgesic and antipyretic properties. Here, we report a case of 21 years old male patient who developed Stevens Johnson Syndrome following ingestion of tablet N
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Dissertations / Theses on the topic "Drug repurp"

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Merikle, Elizabeth Paige 1965. "Development of a self-report measure of drug craving." Diss., The University of Arizona, 1997. http://hdl.handle.net/10150/289233.

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The construct of craving is frequently invoked as a causal factor in on going substance use or in relapse after a period of abstinence. The aim of the present study is to develop a general self-report questionnaire of craving that can be used to assess craving at any point in addiction and recovery. The study was conducted in two phases. In the first phase of the study a sample of 23 addicts were interviewed about their subjective experience of craving. The purpose of this phase of the study was to develop a theory of the subjective experience of craving that could be used to guide the develop
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Thunander, Sundbom Lena. "The influence of gender and depression on drug utilization : Pharmacoepidemiological research in Sweden." Doctoral thesis, Uppsala universitet, Institutionen för farmaci, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-330136.

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Background Drug use has increased over recent decades, and is especially great among women and among people with mental health problems. To take advantage of the full potential of drugs and to avoid drug-related problems, drug prescription needs to be correct and the drugs need to be taken according to the prescribed regimens. Research on drug utilization is thus important to the public health. Aim To study the influence of gender and depression on drug utilization, prescription of drugs and self-reported use of drugs, i.e. adherence. Methods The thesis included two population-based questionna
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Etelvino, Maira Christiane Socorro Duarte. "Curricular training report at risk management directorate." Master's thesis, Universidade de Aveiro, 2014. http://hdl.handle.net/10773/13994.

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Mestrado em Biomedicina Farmacêutica<br>This report is a summary of the activities developed during 9 months of curricular training at the Directorate of Risk Management for Medicines as part of the master degree in Pharmaceutical Medicine. The internship has the purpose of complement the theoretical knowledge previously acquired and was focused on the two areas of the Directorate: Safety Monitoring and Risk Minimization. The activities of the Directorate include the collection and validation of Individual Case Safety Report received from healthcare professionals, patients and pharmaceutical
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Yu, Ai-Ming, Magnus Ingelman-Sundberg, Nathan J. Cherrington, et al. "Regulation of drug metabolism and toxicity by multiple factors of genetics, epigenetics, lncRNAs, gut microbiota, and diseases: a meeting report of the 21 st International Symposium on Microsomes and Drug Oxidations (MDO)." INST MATERIA MEDICA, CHINESE ACAD MEDICAL SCIENCES, 2017. http://hdl.handle.net/10150/623278.

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Variations in drug metabolism may alter drug efficacy and cause toxicity; better understanding of the mechanisms and risks shall help to practice precision medicine. At the 21st International Symposium on Microsomes and Drug Oxidations held in Davis, California, USA, in October 2-6, 2016, a number of speakers reported some new findings and ongoing studies on the regulation mechanisms behind variable drug metabolism and toxicity, and discussed potential implications to personalized medications. A considerably insightful overview was provided on genetic and epigenetic regulation of gene expressi
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Schmid, Gordian L., Franziska Kässner, Holm H. Uhlig, et al. "Sirolimus treatment of severe PTEN hamartoma tumor syndrome: case report and in vitro studies." Nature Research, 2013. https://ul.qucosa.de/id/qucosa%3A38601.

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Background: Phosphatase and tensin homolog (PTEN) hamartoma tumor syndrome (PHTS) is caused by germ line mutations in the PTEN gene. Symptoms include cancer pre- disposition, immune deviations, and lipomas/lipomatosis. No causal standard therapy is available. We describe a therapeutic attempt with the mammalian target of rapamycin (mTOR) inhibitor sirolimus for a PHTS patient suffering from thymus hyperplasia and lipomatosis. We furthermore assessed the in vitro effects of sirolimus and other inhibitors on lipoma cells of the patient. Methods: The patient underwent clinical and blood examinat
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Alhammad, Ali M. "FACTORS INFLUENCING PHARMACISTS’ DECISION TO REPORT ADVERSE EVENTS RELATED TO DIETARY SUPPLEMENTS." VCU Scholars Compass, 2012. http://scholarscompass.vcu.edu/etd/2849.

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Background: The increasing consumption of dietary supplements (DS) has drawn the attention of regulatory agencies, researchers and healthcare professionals. The US Food and Drug Administration (FDA) does not require premarketing assessment of DS considering them safe unless proven otherwise. However, the reporting rate of DS adverse events (DS-AE) is low. Objective: To describe pharmacists’ attitudes and knowledge of DS and DS information resources, and to determine the importance of selected attributes in pharmacists’ decisions to report a DS-AE. Methods: A convenience sample of practicing ph
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DE, ANGELIS ALESSIA. "Nurses’ reporting of Spontaneous Adverse Drug Reactions (ADRs): Identifying the factors that hinder ADRs reporting and testing an explanatory model to predict nurses’ intention to report ADRs." Doctoral thesis, Università degli Studi di Roma "Tor Vergata", 2014. http://hdl.handle.net/2108/203064.

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Background. Adverse drug reactions (ADRs) are an important public health problem associated with mortality, morbidity and an increased financial burden on society and the healthcare system. Spontaneous ADR reporting by healthcare professionals represents a cornerstone of pharmacovigilance (PhV) as it enables an assessment of the risk/benefit ratio of all marketed drugs. Drug withdrawals are often based on data derived from spontaneous reporting systems. However, under-reporting is recognized as the main limitation of ADR reporting systems. In Italy, the current literature gives evi
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Fracon, Ricardo Nogueira. "Avaliação histométrica do reparo ósseo alveolar de ratos tratados com anti-inflamatórios não-esteroidais." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/58/58137/tde-30082010-103722/.

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As prostaglandinas (PGs) são derivadas do metabolismo do ácido aracdônico pela via das enzimas cicloxigenases (COX-1 e COX-2) e participam do controle do metabolismo ósseo. Os anti-inflamatórios não-esteroidais (AINEs), inibidores das COX, podem interferir negativamente com a formação óssea, atrasando o reparo de fratura de ossos longos, a fusão espinhal e a osseointegração de implantes. O presente trabalho teve por objetivo avaliar, quantitativamente, o efeito de diferentes tipos de AINEs (convencional, preferencial e seletivo para COX-2), assim como de um analgésico com efeito anti-inflamató
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Magacho, Edson José de Carvalho. "Adesão ao tratamento na doença renal crônica." Universidade Federal de Juiz de Fora (UFJF), 2010. https://repositorio.ufjf.br/jspui/handle/ufjf/3902.

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Submitted by Renata Lopes (renatasil82@gmail.com) on 2017-03-29T17:33:39Z No. of bitstreams: 1 edsonjosedecarvalhomagacho.pdf: 642099 bytes, checksum: 1b2e21e4489c6bef6338142877dc177b (MD5)<br>Approved for entry into archive by Adriana Oliveira (adriana.oliveira@ufjf.edu.br) on 2017-03-30T11:23:00Z (GMT) No. of bitstreams: 1 edsonjosedecarvalhomagacho.pdf: 642099 bytes, checksum: 1b2e21e4489c6bef6338142877dc177b (MD5)<br>Made available in DSpace on 2017-03-30T11:23:00Z (GMT). No. of bitstreams: 1 edsonjosedecarvalhomagacho.pdf: 642099 bytes, checksum: 1b2e21e4489c6bef6338142877dc177b (MD5)
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Poleti, Marcelo Lupion. "Análise morfométrica, radiográfica e molecular do processo de reparo alveolar após a terapia fotodinâmica antimicrobiana em ratos Wistar." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/25/25132/tde-03072009-105031/.

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Introdução: Com o aumento da resistência bacteriana à antibioticoterapia tornou-se necessário o desenvolvimento de técnicas antimicrobianas alternativas. Assim, na busca de novas metodologias contra microrganismos, estudos usando a Terapia Fotodinâmica (TFD) antimicrobiana tem sido realizados. Objetivo: Realizar análise morfométrica, radiográfica e molecular do processo de reparo alveolar após a TFD antimicrobiana em ratos Wistar. Material e Métodos: Foram utilizados 85 ratos, divididos nos seguintes grupos: GRUPO C: Animais com alvéolo não tratado (grupo controle); GRUPO S+L: Animais com alvé
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Books on the topic "Drug repurp"

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Europol, ed. EU drug markets report: A strategic analysis. Publications Office of the European Union, 2013.

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WHO Expert Committee on the Use of Essential Drugs. Meeting, ed. The Use of essential drugs: Second report of the WHO Expert Committee. World Health Organization, 1985.

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Canadian Bar Association. Ontario Branch. Committee to Study the Implications of Mandatory Drug Testing in the Workplace. Report on mandatory drug testing. Canadian Bar Association-Ontario, 1987.

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Organization, World Health, and WHO Expert Committee on the Use of Essential Drugs. Meeting, eds. The Use of essential drugs: Sixth report of the WHO Expert Committee. World Health Organization, 1995.

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A, Bellis Mark, Great Britain. Department of Health. UK Focal Point on Drugs., and European Monitoring Centre for Drugs and Drug Addiction., eds. United Kingdom drug situation: Annual report to the Europe Monitoring Centre for Drugs and Drug Addiction (EMCDDA). UK Focal Point on Drugs, 2003.

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United Nations International Drug Control Programme., ed. World drug report. Oxford University Press, 1997.

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Initiative, Drugs Prevention. Annual progress report. Home Office Central Drugs Prevention Unit, 1995.

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Initiative, Drugs Prevention. Annual progress report. Home Office Central Drugs Prevention Unit, 1997.

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WHO Expert Committee on the Use of Essential Drugs. Meeting, ed. The Use of essential drugs: Third report of the WHO Expert Committee. World Health Organization, 1988.

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United States. Drug Enforcement Administration. Office of Diversion Control., United States. Drug Enforcement Administration., and European Commission, eds. Middle East Drug and Chemical Diversion Control Conference : conference report : report. The Administration, 1996.

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Book chapters on the topic "Drug repurp"

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Nahler, Gerhard. "drug experience report." In Dictionary of Pharmaceutical Medicine. Springer Vienna, 2009. http://dx.doi.org/10.1007/978-3-211-89836-9_432.

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"Illegal drug supply innovations and synthetic drugs." In World Drug Report. United Nations, 2023. http://dx.doi.org/10.18356/9789210028233c014.

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Fentiman, Linda C. "Drug Use by Pregnant Women." In Blaming Mothers. NYU Press, 2017. http://dx.doi.org/10.18574/nyu/9780814724828.003.0005.

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This chapter examines the use of drugs—both legal and illegal–by pregnant women, noting increased medical and legal supervision of pregnancy and women’s substance use and abuse. Many states require health care professionals to report pregnant women who admit to, or are suspected of, using alcohol or other drugs. The result can be involuntary detention commitment for “treatment.” Women have been prosecuted for homicide after they suffer a stillbirth despite weak evidence that the stillbirth was caused by drug use. Prosecution of these women is counterproductive, because it drives pregnant drug
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"Drug-by-drug developments in brief." In World Drug Report. United Nations, 2022. http://dx.doi.org/10.18356/9789210019545c007.

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"Drug-by-drug developments in brief." In World Drug Report. United Nations, 2023. http://dx.doi.org/10.18356/9789210028233c006.

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"Drug-by-drug developments in brief." In World Drug Report. United Nations, 2022. http://dx.doi.org/10.18356/9789210058032c006.

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"Drug-by-drug developments in brief." In World Drug Report. United Nations, 2024. https://doi.org/10.18356/9789211065534c004.

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"Drug supply." In World Drug Report. United Nations, 2022. http://dx.doi.org/10.18356/9789210058032c015.

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"Drug demand." In World Drug Report. United Nations, 2022. http://dx.doi.org/10.18356/9789210058032c014.

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Chole, Pranjali, Camil Rex, Sabia Imran, Kasi Gopinath, and Lokesh Ravi. "Nano-particles for Microbial Growth and Drug Delivery." In Frontiers in Antimicrobial Agents. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/9789815080056123020013.

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The development of drug resistance in microorganisms has become one of the greatest global health challenges, as microorganisms tend to adapt to organic drugs via several mechanisms. Multi-drug resistance (MDR) in microorganisms not only increases the mortality rate of humans, but clinicians are also running out of options to treat MDR infections. A solution to this problem could be found in inorganic chemistry, where metal elements are converted in to nanoparticles that function as both drug and drug delivery agents to control microbial growth and overcome the resistance imposed on organic dr
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Conference papers on the topic "Drug repurp"

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Maloney, John M. "An Implantable Microfabricated Drug Delivery System." In ASME 2003 International Mechanical Engineering Congress and Exposition. ASMEDC, 2003. http://dx.doi.org/10.1115/imece2003-43186.

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We report on the development of a fully implantable drug delivery system capable of delivering hundreds of individual doses. This product is intended for the controlled release of potent therapeutic compounds that might otherwise require frequent injections. Our system has the following capabilities: • Stable, hermetic storage of therapeutic drugs in solid, liquid, or gel form; • Individual storage of discrete doses for multiple-drug regimens; • Wireless communication with an external controller for device monitoring and therapy modification; • Choice of preprogrammed release or release on com
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Liang, Ruqiang, Junqing Sun, Ryan Gregory Natan, et al. "Fluorescent imaging of synaptic glutamate transients in defined neuronal circuits." In Optical Molecular Probes, Imaging and Drug Delivery. Optica Publishing Group, 2023. http://dx.doi.org/10.1364/omp.2023.otu3e.4.

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A splittable genetically encoded intensimetric fluorescent sensor for glutamate is engineered. It can reconstitute across synaptic clefts and report glutamate transients when the nonfluorescent halves are targeted to pre- and post-synaptic neurons in a circuit.
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Christie, D. J., H. Diaz-Arauzo, and J. M. Cook. "REACTIONS OF DRUG-DEPENDENT ANTIBODIES WITH METABOLITES OF QUININE (Qn) AND QUINIDINE (Qd)." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644578.

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In many cases of drug-induced immunologic thrombocytopenia (DITP), a metabolite, rather than the native drug, is suspected of provoking the destructive drug-dependent antibodies (DDAB) responsible for this severe hemorrhagic disorder. However, this has not previously been investigated for Qn- and Qd-DDAB. We report evidence that the native drugs, and not their metabolites, are the provocative agents in Qn and Qd DITP. Reactions of Qn- and Qd-DDAB with platelets were studied with the native drugs and four of their metabolites: the N-oxide and 10,11-diol derivatives (quinuclidine ring modificati
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Zhang, Wujie, Kyle Gilstrap, Laying Wu, et al. "Controlled Release and Intracellular Delivery of Small Molecules Using Thermally Responsive Pluronic F127-Chitosan Nanocapsules." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53517.

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Nanoscale particulate systems have been studied as the delivery vehicle of various drugs and therapeutic agents for decades with promising outcomes. Recently, nano-particulate systems that are responsive to one or more environmental stimuli (such as temperature, pH, and electromagnetic field) are attracting increasing attention because they allow drug delivery and release to be done in a more controllable fashion [1]. The thermally (temperature) responsive nanoparticles are of particular interest to many researchers because the temperature controlled release of the encapsulated drug can be con
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Jayasuriya, A. Champa, Anthony Darr, and Nabil A. Ebraheim. "Chemotherapy Drug Encapsulated Poly(Lactic-Co-Glycolic Acid) Nanoparticles." In ASME 2006 International Mechanical Engineering Congress and Exposition. ASMEDC, 2006. http://dx.doi.org/10.1115/imece2006-14694.

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In order to exhibit pharmacological activity at the bone cancer site, high-dose chemotherapy drugs need to be used. This often causes toxicity and unfavorable systemic adverse effects leading to significant problems to the patient. Since nanoparticles are in subcellular size, they can effectively entered to the cell membrane that could result in higher cellular uptake. In this study, we report preparation and characterization of poly(lactic-co-glycolic acid) - PLGA nanoparticles, which encapsulated with chemotherapy drug cisplatin.
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Lichtenfels, Martina, Mário Casales Schorr, Isis Mendes Barbosa, Caroline Brunetto de Farias, and José Luiz Pedrini. "A novel in vitro breast cancer chemoresistance platform." In XXVI Brazilian Mastology Congress. Mastology, 2024. https://doi.org/10.29289/259453942024v34s2042.

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Introduction: Breast cancer (BC) is a highly heterogeneous disease characterized by distinct molecular subtypes and prognoses. Tumor resistance is the main cause of treatment failure, leading to cancer progression. Despite the knowledge of different drug resistance mechanisms in BC cells, overcoming resistance is still challenging. Therefore, predicting resistance before initiating chemotherapy is valuable for increasing treatment benefits. Functional precision medicine is an innovative treatment strategy in which drugs are tested on the patient’s cancer cells, cultured outside the body, to un
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von Broen, M., M. Scherf-Clavel, J. Deckert, and S. Unterecker. "Sertraline concentration in serum unaffected by hemodialysis: a case report." In XVth Symposium of the Task Force Therapeutic Drug Monitoring of the AGNP. Georg Thieme Verlag, 2024. http://dx.doi.org/10.1055/s-0044-1779570.

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Wang, Charles C. N., David A. Hecht, Phillip C.-Y. Sheu, and Jeffrey J. P. Tsai. "Semantic Computing and Drug Discovery - A Preliminary Report." In 2013 IEEE Seventh International Conference on Semantic Computing (ICSC). IEEE, 2013. http://dx.doi.org/10.1109/icsc.2013.86.

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"A CASE REPORT : INTRAVENOUS DRUG ABUSE OF TRIHEXYPHENIDYL." In 8th World Congress of the World Association of Dual Disorders (WADD) and the 26th Congress of the Spanish Society of Dual Disorders SEPD. SEPD/WADD, 2024. http://dx.doi.org/10.17579/abstractbookdualdisorders-p-188.

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Nikkhah, Mehdi, Jeannine S. Strobl, and Masoud Agah. "Study the Effect of Anticancer Drugs on Human Breast Cancer Cells Using Three Dimensional Silicon Microstructures." In ASME 2008 International Mechanical Engineering Congress and Exposition. ASMEDC, 2008. http://dx.doi.org/10.1115/imece2008-66680.

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In this paper we report development of three dimensional silicon microenvironments in order to test the morphological changes and adhesion properties of human breast cancer cells after treatment with different anticancer drugs such as Trichostatin A (TSA), suberoylanilide hydroxamic acid (SAHA) and Scriptaid. Our results indicate that the cancer cells reorganize their cytoskeleton structure after treatment with TSA and Scriptaid. However, SAHA does not change the behavior of the cells inside the three dimensional microstructures while TSA and Scriptaid evoked striking changes in the cells morp
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Reports on the topic "Drug repurp"

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Garnett, Matthew, and Arialdi Miniño. Changes in Drug Overdose Mortality and Selected Drug Type by State in the United States, 2022 to 2023. National Center for Health Statistics (U.S.), 2025. https://doi.org/10.15620/cdc/174578.

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Hedegaard, Holly. Urban–Rural Differences in Drug Overdose Death Rates, 1999–2019. National Center for Health Statistics, 2021. http://dx.doi.org/10.15620/cdc:102891.

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This report uses the most recent mortality data from the National Vital Statistics System (NVSS) to examine urban–rural differences in drug overdose death rates, for all drugs and by selected types of opioids and stimulants.
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Spencer, Merianne, Arialdi Miniño, and Margaret Warner. Drug Overdose Deaths in the United States, 2001–2021. National Center for Health Statistics (U.S.), 2022. http://dx.doi.org/10.15620/cdc:122556.

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This report uses the most recent data from the National Vital Statistics System to update statistics on deaths from drug overdose in the United States. It shows rates by demographic groups and types of drugs involved, with a focus on changes from 2020 through 2021.
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Hedegaard, Holly, Arialdi Miniño, Merianne Rose Spencer, and Margaret Warner. Drug Overdose Deaths in the United States, 1999–2020. National Center for Health Statistics ( U.S.), 2021. http://dx.doi.org/10.15620/cdc:112340.

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This report uses the most recent data from the National Vital Statistics System (NVSS) to update statistics on deaths from drug overdose in the United States, showing rates by demographic group and by specific types of drugs involved (such as opioids or stimulants), with a focus on changes from 2019 to 2020.
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Hedegaard, Holly, Arialdi M. Miniño, Merianne Rose Spencer, and Margaret Warner. Drug Overdose Deaths in the United States, 1999–2020. National Center for Health Statistics ( U.S.), 2021. http://dx.doi.org/10.15620/cdc:112644.

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This report uses the most recent data from the National Vital Statistics System (NVSS) to update statistics on deaths from drug overdose in the United States, showing rates by demographic group and by specific types of drugs involved (such as opioids or stimulants), with a focus on changes from 2019 to 2020.
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Miller, Lauren. Drowning involving alcohol and drugs: 2019/20 to 2023/24. Royal Life Saving - Australia, 2024. http://dx.doi.org/10.62977/87209.

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Alcohol consumption is known to impair our cognitive functions, influencing behaviour and risk-perception. The Australian water safety strategy identifies alcohol and drug consumption to be a major risk factor in drowning events, highlighting the need to understand more around the characteristics of these behaviours. This brief report covers a 5-year period on all alcohol and drugs present at the time of the drowning event, broken down by demographics, and whether the alcohol and/or drugs consumed were found to contribute to the drowning event.
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Venedicto, Melissa, and Cheng-Yu Lai. Facilitated Release of Doxorubicin from Biodegradable Mesoporous Silica Nanoparticles. Florida International University, 2021. http://dx.doi.org/10.25148/mmeurs.009774.

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Cervical cancer is one of the most common causes of cancer death for women in the United States. The current treatment with chemotherapy drugs has significant side effects and may cause harm to healthy cells rather than cancer cells. In order to combat the potential side effects, nanoparticles composed of mesoporous silica were created to house the chemotherapy drug doxorubicin (DOX). The silica network contains the drug, and a pH study was conducted to determine the conditions for the nanoparticle to disperse the drug. The introduction of disulfide bonds within the nanoparticle created a fram
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Sisco, Edward. Drug Detection, Analysis, and Monitoring Workshop Report. National Institute of Standards and Technology, 2024. http://dx.doi.org/10.6028/nist.sp.1500-24.

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MacDougall, Preston. Computational modeling of drug-resistant bacteria. Final report. Office of Scientific and Technical Information (OSTI), 2015. http://dx.doi.org/10.2172/1172320.

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Spencer, Merianne, Matthew Garnett, and Arialdi Miniño. Drug Overdose Deaths in the United States, 2002-2022. National Center for Health Statistics (U.S.), 2023. http://dx.doi.org/10.15620/cdc:135849.

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