Relevant bibliographies by topics / Drug therapiy

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Drug therapiy'

Author: Grafiati
Published: 4 June 2021
Last updated: 14 February 2022

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Journal articles on the topic "Drug therapiy"

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Petrak, Karel. "The Difference between Targeted Drug Therapies and Targeted-Drug Therapies." Cancer Research and Cellular Therapeutics 2, no. 4 (2018): 01–03. http://dx.doi.org/10.31579/2640-1053/032.

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Isnenia, Isnenia. "Penggunaan Non-Steroid Antiinflamatory Drug dan Potensi Interaksi Obatnya Pada Pasien Muskuloskeletal." Pharmaceutical Journal of Indonesia 6, no. 1 (2020): 47–55. http://dx.doi.org/10.21776/ub.pji.2020.006.01.8.

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The main therapy on musculoskeletal patients is the use of non-steroidal anti-inflammatory drugs (NSAIDs) either as monotherapy or in combination with drugs of the same class or pain relievers from other groups. The use of more than one drugs have potentially caused drug-drug interactions that can affect to patient. This study was aimed to describe the patient's sociodemographic (sex, ages) and clinical (numbers of drugs, type of drugs and diagnose) characteristics, as well as to find the correlation between potential drug interactions with these variables. This research was a quantitative stu
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R., Akobova, та Ryzhakin S.M. "КОНСЕРВАТИВНАЯ ТЕРАПИЯ ДОБРОКАЧЕСТВЕННОЙ ГИПЕРПЛАЗИИ ПРЕДСТАТЕЛЬНОЙ ЖЕЛЕЗЫ". Bulletin "Biomedicine and sociology" 4, № 2 (2019): 21–24. http://dx.doi.org/10.26787/nydha-2618-8783-2019-4-2-21-24.

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Ulfah, Nurbani. "Evaluasi Program Art Therapy Bagi Pasien Dual Diagnosis (NAPZA-Skizofrenia) di Rumah Sakit Ketergantungan Obat (RSKO) Jakarta." EMPATI: Jurnal Ilmu Kesejahteraan Sosial 4, no. 1 (2015): 58–77. http://dx.doi.org/10.15408/empati.v4i1.9767.

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The main problem drug users with psychiatric disorders is the difficulty of communicating the reason they use drugs and express their feelings on the condition of the Counselor or Social Worker (Therapist). The existence of the program of art therapy for patients with drug with psychiatric disorders (dual diagnosis) is part of psychotherapy as an adjunct therapy in the form of art to channel emotions, express their feelings when communicate verbally is difficult, and to express themselves freely in order to improve their condition in the direction better in recovering. In an effort to redress
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Chen, Fengqian, Yunzhen Shi, Jinming Zhang, and Qi Liu. "Nanoparticle-based Drug Delivery Systems for Targeted Epigenetics Cancer Therapy." Current Drug Targets 21, no. 11 (2020): 1084–98. http://dx.doi.org/10.2174/1389450121666200514222900.

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This review summarizes the epigenetic mechanisms of deoxyribonucleic acid (DNA) methylation, histone modifications in cancer and the epigenetic modifications in cancer therapy. Due to their undesired side effects, the use of epigenetic drugs as chemo-drugs in cancer therapies is limited. The drug delivery system opens a door for minimizing these side effects and achieving greater therapeutic benefits. The limitations of current epigenetic therapies in clinical cancer treatment and the advantages of using drug delivery systems for epigenetic agents are also discussed. Combining drug delivery sy
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Leary, Meghan, Sarah Heerboth, Karolina Lapinska, and Sibaji Sarkar. "Sensitization of Drug Resistant Cancer Cells: A Matter of Combination Therapy." Cancers 10, no. 12 (2018): 483. http://dx.doi.org/10.3390/cancers10120483.

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Cancer drug resistance is an enormous problem. It is responsible for most relapses in cancer patients following apparent remission after successful therapy. Understanding cancer relapse requires an understanding of the processes underlying cancer drug resistance. This article discusses the causes of cancer drug resistance, the current combination therapies, and the problems with the combination therapies. The rational design of combination therapy is warranted to improve the efficacy. These processes must be addressed by finding ways to sensitize the drug-resistant cancers cells to chemotherap
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Goyal, Pardeep Kumar, Shalini Arora, Naveen Mittal, Bharti Mahajan, and Sandeep Kaushal. "Prescribing pattern and pharmacoeconomic analysis of antidiabetic drugs." International Journal of Basic & Clinical Pharmacology 8, no. 8 (2019): 1844. http://dx.doi.org/10.18203/2319-2003.ijbcp20193188.

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Background: Diabetes Mellitus is a worldwide growing problem causing threat to patient's health because of its association with various complications and comorbidities. It is a chronic disease requiring lifelong medication which further adds to the economic burden. The objective of this study was to evaluate the prescribing pattern and to do pharmacoeconomic analysis of prescribed antidiabetic drugs.Methods: This observational cross sectional study was conducted for 12 months duration in Outpatient Pharmacy of tertiary care hospital. Prescriptions with antidiabetic drugs were captured and eval
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Nishimura, Kaneyasu, and Kazuyuki Takata. "Combination of Drugs and Cell Transplantation: More Beneficial Stem Cell-Based Regenerative Therapies Targeting Neurological Disorders." International Journal of Molecular Sciences 22, no. 16 (2021): 9047. http://dx.doi.org/10.3390/ijms22169047.

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Cell transplantation therapy using pluripotent/multipotent stem cells has gained attention as a novel therapeutic strategy for treating neurodegenerative diseases, including Parkinson’s disease, Alzheimer’s disease, Huntington’s disease, ischemic stroke, and spinal cord injury. To fully realize the potential of cell transplantation therapy, new therapeutic options that increase cell engraftments must be developed, either through modifications to the grafted cells themselves or through changes in the microenvironment surrounding the grafted region. Together these developments could potentially
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Vandamme, A.-M., K. Van Vaerenbergh, and E. De Clercq. "Anti-Human Immunodeficiency Virus Drug Combination Strategies." Antiviral Chemistry and Chemotherapy 9, no. 3 (1998): 187–203. http://dx.doi.org/10.1177/095632029800900301.

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It is now generally accepted that mono- and bitherapy for human immunodeficiency virus type 1 (HIV-1) infection are only transiently efficient mainly due to virus drug resistance. To obtain a sustained benefit from antiviral therapy, current guidelines recommend at least triple-drug combinations, or the so-called highly active antiretroviral therapy (HAART). In some patients, HAART can be problematic, either because it is difficult to remain compliant or because previous suboptimum therapies have limited the choice of drugs. For compliant drug-naive patients, HAART should be able to offer long
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Su, Yifan. "The Molecular Mechanism and Drug Therapy of Heart Failure." International Journal of Environmental Science and Development 11, no. 9 (2020): 455–59. http://dx.doi.org/10.18178/ijesd.2020.11.9.1290.

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Heart failure (HF) is a complex clinical syndrome that results from left ventricular myocardial dysfunction and contributes to dyspnea, fatigue and fluid retention. It's essential to characterize disease progression and symptoms to optimize therapy selection. Also, understanding the mechanisms of HF to guide therapy selection is of vital importance. This review focuses on the demonstrating mechanisms of HF and points out the possible pathways involved in the process. Drug therapies of HF with different effects on specific targets are analyzed. Finally, we conclude the features of the now going
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Dissertations / Theses on the topic "Drug therapiy"

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Mathis, Leigh Ann. "Student Psychotropic Drug Use, Past Therapy Experience and Length of Therapy." TopSCHOLAR®, 2008. http://digitalcommons.wku.edu/theses/49.

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Murphy, Jennifer. "Therapy and Punishment: Negotiating Authority in the Management of Drug Addiction." Diss., Temple University Libraries, 2008. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/8969.

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Sociology<br>Ph.D.<br>Throughout the twentieth century, many behaviors previously considered criminal or immoral were instead defined as medical problems. This process is often referred to as the medicalization of deviance. Like many other behaviors once considered deviant, drug and alcohol abuse has been medicalizing, in a process that accelerated during the latter half of the twentieth century. Despite this movement along the path toward medicalization, drug use, and alcohol use to a lesser extent, are still also sanctioned and managed by the criminal justice system, resulting in a medical-l
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Gustafsson, Maria. "Optimizing drug therapy among people with dementia : the role of clinical pharmacists." Doctoral thesis, Umeå universitet, Geriatrik, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-118309.

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Background: Drugs are one of the cornerstones in the management of many diseases. In general, drugs are used for diagnosis, prevention, mitigation of symptoms, and, sometimes, to cure disease. However, drug treatment in elderly people, especially those with dementia and cognitive impairments, may involve significant risk of adverse drug events.  The aim of this thesis was to identify the extent of potentially inappropriate drug treatment among people with dementia and cognitive impairment and to assess the occurrence and character of drug-related problems that lead to acute hospital admissions
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O'Callaghan, Christopher. "Aerosolised drug therapy in infancy." Thesis, University of Nottingham, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.305089.

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Pandie, Mishal. "Drug-drug interactions between antiretrovirals and bedaquiline." Master's thesis, University of Cape Town, 2017. http://hdl.handle.net/11427/27401.

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Tuberculosis (TB) is a leading cause of morbidity and mortality worldwide. People living with HIV are particularly susceptible to TB infection, and treatment of HIV-TB co-infection is challenging for multiple reasons, including potential drug-interactions. Drug-resistant TB is difficult to treat and is associated with high treatment failure rates, mainly because the antimycobacterial drugs currently available are ineffective against drug-resistant TB. Bedaquiline is a new antimycobacterial drug which has shown great promise through its excellent efficacy for treating drug-resistant TB. Being a
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Nambatya, Winnie. "Monitoring lipid and haematological abnormalities in paediatric patients on antiretroviral therapy at a Community Health Centre in the Cape Metropole." University of the Western Cape, 2014. http://hdl.handle.net/11394/4328.

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Magister Pharmaceuticae - MPharm<br>South Africa faces a huge Human Immunodeficiency Virus (HIV) burden with more than 400,000 children currently on antiretroviral therapy (ART). Studies on lipid and haematological profile changes in paediatrics are of particular interest since these children are exposed to ART in the course of a developmentally significant period and will possibly have longer collective exposure to ART. As such, monitoring for adverse effects, including lipid and haematological abnormalities, is essential for curtailing morbidity and mortality rates of children on ART. There
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Zi, Hong. "Polymers for drug delivery in cancer therapy /." May be available electronically:, 2008. http://proquest.umi.com/login?COPT=REJTPTU1MTUmSU5UPTAmVkVSPTI=&clientId=12498.

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Alfahad, Mohanad Abdul-Satar Mahmood. "Pro-drug strategies for pancreatic cancer therapy." Thesis, Keele University, 2018. http://eprints.keele.ac.uk/4534/.

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Pancreatic cancer is the fourth main cancer in the western world. Currently the only chemotherapy available clinically is gemcitabine. However, gemcitabine treatment only proves effective in 23.8% of patients. Nano-structures (< 120 nm) are capable of entering the highly permeable blood capillaries which supply the rapidly growing tumours. Once inside the capillaries they accumulate and are retained in the tumour as a result of the poor lymphatic drainage. This allows for a deeper tissue penetration which is otherwise difficult to achieve. Hybrid nanoparticles with an iron oxide core covered b
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Morrow, D. I. J. "Novel Drug Delivery Approaches to Photodynamic Therapy." Thesis, Queen's University Belfast, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.502072.

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Yung, Bryant Chinung. "NANOPARTICLE DRUG DELIVERY SYSTEMS FOR CANCER THERAPY." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1417614665.

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Books on the topic "Drug therapiy"

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Schneeweiss, Adam. Cardiovascular drug therapy: Nitrate therapy. Springer-Verlag, 1990.

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Gonsoulin, Sheryl M. Prehospital drug therapy. Mosby Lifeline, 1994.

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1925-, Powers Thomas E., ed. Veterinary drug therapy. Lea & Febiger, 1994.

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Khan, M. Gabriel. Cardiac drug therapy. 3rd ed. W.B. Sanders, 1992.

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Schneeweiss, Adam. Cardiovascular Drug Therapy. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-74617-8.

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Khan, M. Gabriel. Cardiac Drug Therapy. Humana Press, 2015. http://dx.doi.org/10.1007/978-1-61779-962-4.

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J, Sanders Mick, and Raynovich William, eds. Prehospital drug therapy. 2nd ed. Mosby, 2002.

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Therapy-resistant schizophrenia. Karger, 2010.

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T, Nagle Barbara, ed. Basic pharmacology for health occupations. 3rd ed. Glencoe, 1994.

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Hitner, Henry. Basic pharmacology for health occupations. 2nd ed. Glencoe Publishing Co., 1987.

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Book chapters on the topic "Drug therapiy"

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Stock, John L. "Drug Therapy." In Osteoporosis. Humana Press, 1996. http://dx.doi.org/10.1007/978-1-4612-0221-9_15.

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Swift, C. G. "Drug Therapy." In Geriatric Medicine. Springer London, 1989. http://dx.doi.org/10.1007/978-1-4471-1646-2_24.

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Pastrana, R. "Drug therapy." In Back Pain. Springer Netherlands, 1990. http://dx.doi.org/10.1007/978-94-009-2165-8_16.

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Swerdlow, Mark, and Vittorio Ventafridda. "Drug Therapy." In Cancer Pain. Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-010-9139-8_7.

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He, Ri-Hui, and Ran Tao. "Drug Therapy." In Advances in Experimental Medicine and Biology. Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-5562-1_11.

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Bloxham, Jill. "Drug Therapy." In Perspectives in Nursing Management and Care for Older Adults. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-18012-6_9.

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Lee, Juhee, and Jihee Kim. "Emerging Technologies in Scar Management: Laser-Assisted Delivery of Therapeutic Agents." In Textbook on Scar Management. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-44766-3_50.

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AbstractTopical application of medications is difficult through intact skin due to physiological barrier of stratum corneum. Effective transdermal drug delivery system can offer distinct advantages over the topical application and oral administration of drugs. Laser systems have showed clinical benefits for patients in various types of scars for decades. In particular, the advent of fractional resurfacing advanced laser has enhanced the scar treatments dramatically. A fractional laser irradiates cells with high precision by controlling the area and degree of ablation through laser settings. In addition to local thermal destruction and stimulation, fractionated devices may also play an important role in drug delivery through the skin. Preclinical studies substantiate enhanced drug accumulation for a variety of topically applied drugs after ablative fractional laser therapy. Laser-assisted drug delivery is an evolving technology with potentially broad clinical applications. Multiple studies demonstrate that laser pretreatment of the skin can increase the permeability and depth of penetration of topically applied drug molecules. We discuss the mechanisms of laser-assisted drug delivery for scar treatment to enhance our understanding of this evolving technology and suggest optimal protocols of treatment.
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Borchert, Jill S. "Considerations with Pharmacodynamic Drug-Drug Interactions." In Oral Anticoagulation Therapy. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-54643-8_30.

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Ieuter, Rachel C. "Pharmacokinetic Drug-Drug Interactions with Warfarin." In Oral Anticoagulation Therapy. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-54643-8_32.

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Maffei, Frank A. "Cardiovascular Drug Therapy." In Pediatric Critical Care Study Guide. Springer London, 2011. http://dx.doi.org/10.1007/978-0-85729-923-9_17.

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Conference papers on the topic "Drug therapiy"

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Bano, Dr Zaheda, Dr P. N. Amaranath, and Sk Farida. "Combination Drug Therapy versus Single Drug Therapy." In Annual International Conference on Pharmacology and Pharmaceutical Sciences. Global Science & Technology Forum (GSTF), 2014. http://dx.doi.org/10.5176/2345-783x_pharma14.49.

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Kobayashi, Kanako, Shuichi Yano, and Toshikazu Ikeda. "Adjunctive Corticosteroid Therapy For Adverse Drug Reactions Due To Antituberculous Drugs." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a4913.

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Sokolov, Victor V. "First clinical results with a new drug for PDT." In Photodynamic Therapy of Cancer II. SPIE, 1995. http://dx.doi.org/10.1117/12.199168.

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Yu, Ruixia, Hualing Chen, Tianning Chen, and Hairong Wang. "Topology Optimization of MEMS-Based Biodegradable Controlled Drug Delivery System for Combination Therapy." In 2007 First International Conference on Integration and Commercialization of Micro and Nanosystems. ASMEDC, 2007. http://dx.doi.org/10.1115/mnc2007-21175.

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MEMS-based biodegradable controlled release system with micro multi-chambers can respectively enclose two drugs in different chambers to realize a combination therapy. In order to synchronously obtain the linear release of two drugs, it is necessary to completely investigate the topology optimization of the system. This paper introduces the theory of multi-objective topology optimization into MEMS-based biodegradable controlled release system for the combination therapy. Furthermore, a new method of CA-based evolutionary structural optimization (CA-ESO) is presented to accomplish the topology
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Jandhyala, Sidhartha, and Geoffrey P. Luke. "Optically Activated Oxygen-Loaded Perfluorocarbon Nanoparticles for Ultrasound-guided Radiation Therapy." In Optical Molecular Probes, Imaging and Drug Delivery. OSA, 2017. http://dx.doi.org/10.1364/omp.2017.omw3d.7.

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Mendes, Pedro J., Joa˜o M. M. Sousa, and Joa˜o F. Pinto. "A Virtual Apparatus for Design and Testing of New Drug Formulations and Devices for Inhalation Therapy." In ASME 2007 2nd Frontiers in Biomedical Devices Conference. ASMEDC, 2007. http://dx.doi.org/10.1115/biomed2007-38027.

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Delivery of drugs to the lungs as aerosols is regarded as an excellent route for local or systemic administration of drugs. Aerosols have been used traditionally for treating illnesses of the respiratory tract (e.g. asthma), but new perspectives and needs on inhalation therapy have recently emerged (e.g. insulin). The percentage of drug that reaches the targeted region, the so-called respirable fraction (RF), is in average only 30% of the dose provided to the patient. Thus, the development of more efficient formulations and devices remains an important issue.
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Lyu, Tengfei, Jianliang Gao, Ling Tian, Zhao Li, Peng Zhang, and Ji Zhang. "MDNN: A Multimodal Deep Neural Network for Predicting Drug-Drug Interaction Events." In Thirtieth International Joint Conference on Artificial Intelligence {IJCAI-21}. International Joint Conferences on Artificial Intelligence Organization, 2021. http://dx.doi.org/10.24963/ijcai.2021/487.

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The interaction of multiple drugs could lead to serious events, which causes injuries and huge medical costs. Accurate prediction of drug-drug interaction (DDI) events can help clinicians make effective decisions and establish appropriate therapy programs. Recently, many AI-based techniques have been proposed for predicting DDI associated events. However, most existing methods pay less attention to the potential correlations between DDI events and other multimodal data such as targets and enzymes. To address this problem, we propose a Multimodal Deep Neural Network (MDNN) for DDI events predic
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Nascimento, Letícia A., Érica C. M. Nascimento, and João B. L. Martins. "Análise da estrutura eletrônica da tacrina e do neurotransmissor acetilcolina." In VIII Simpósio de Estrutura Eletrônica e Dinâmica Molecular. Universidade de Brasília, 2020. http://dx.doi.org/10.21826/viiiseedmol2020150.

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Alzheimer's disease (AD) is a more common neurodegenerative process in the elderly population, characterized by a progressive loss of cognitive abilities, such as memory, language skills, disorientation, attention and depression. Cholinergic hypothesis therapy is the most successful approach for the symptomatic treatment of AD. The therapy consists in the use of drugs with inhibitory action against acetylcholinesterase (AChE) to avoid the decrease of acetylcholine concentration in synaptic clefts. Thus, this research aims to carry out the electronic and structural study of tacrina drug compare
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Dereli-Korkut, Zeynep, and Sihong Wang. "Microfluidic Cell Arrays to Mimic 3D Tissue Microenvironment." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80411.

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We developed a functional high throughput 3D microfluidic living cell array (MLC) for anti-cancer drug screening and mechanism discovery. Contemporary drug screening methods suffer from low sample throughput and lack of abilities of mimicking the 3D microenvironment of mammalian tissues. The poor performance of anti-cancer drugs limits the efficacy at controlling the complex disease system like cancer. Systematic studies of apoptotic signaling pathways can be prominent approaches for searching active and effective treatments with less drug resistance. Hence, innovative bio-devices are needed t
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Лифшиц, Г., G. Lifshic, Е. Зеленкская, et al. "Association of polymorphisms Gene CYP2C19 with endpoints of efficacy and safety of clopidogrel therapy And platelet aggregation in patients with acutecoronary syndrome study Protocol." In Topical issues of translational medicine: a collection of articles dedicated to the 5th anniversary of the day The creation of a department for biomedical research and technology of the Irkutsk Scientific Center Siberian Branch of RAS. INFRA-M Academic Publishing LLC., 2017. http://dx.doi.org/10.12737/conferencearticle_58be81ec9680e.

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Aim: to reveal the association of gene CYP2C19 polymorphisms and efficacy and safety endpoints of clopidogrel therapy in patients with acute coronary syndrome. Materials and methods. A total of 431 patients with acute coronary syndrome undergoing coronary stent placement was studied. CYP2C19 polymorphisms (*2, *3, *17) were evaluated, platelet aggregation with ADP and efficacy and safety for 30 days after coronary stent placement was studied. Results. Within the selected patients there was no significant association between carriage of at least one allele of the CYP2C19*2, and/or CYP2C19*3 and
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Reports on the topic "Drug therapiy"

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Esenaliev, Rinat O. Novel Drug Delivery Technique for Breast Cancer Therapy. Defense Technical Information Center, 2003. http://dx.doi.org/10.21236/ada418735.

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Esenaliev, Rinat O. Novel Drug Delivery Technique for Breast Cancer Therapy. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada410175.

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Esenaliev, Rinat O. Novel Drug Delivery Technique for Breast Cancer Therapy. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada435264.

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Fink, Howard A., Roderick MacDonald, Mary L. Forte, et al. Long-Term Drug Therapy and Drug Holidays for Osteoporosis Fracture Prevention: A Systematic Review. Agency for Healthcare Research and Quality (AHRQ), 2019. http://dx.doi.org/10.23970/ahrqepccer218.

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Brown, Elizabeth, and Roger Dmochowski . Drug therapies for OAB - which anti-muscarinic? BJUI Knowledge, 2020. http://dx.doi.org/10.18591/bjuik.0075.

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Brown, Elizabeth, and Roger Dmochowski. Drug therapies for OAB - which anti-muscarinic? BJUI Knowledge, 2020. http://dx.doi.org/10.18591/bjuik.0075.v2.

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Mourant, J., I. Biglo, and T. Johnson. Measurement of photodynamic therapy drug concentrations in a tissue. Office of Scientific and Technical Information (OSTI), 1996. http://dx.doi.org/10.2172/374406.

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Foroozesh, Maryam. A Drug Discovery Partnership for Personalized Breast Cancer Therapy. Defense Technical Information Center, 2012. http://dx.doi.org/10.21236/ada568389.

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Foroozesh, Maryam, Thomas Weise, Jayalakshmi Sridhar, et al. A Drug Discovery Partnership for Personalized Breast Cancer Therapy. Defense Technical Information Center, 2013. http://dx.doi.org/10.21236/ada590425.

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Donahue, Katrina E., Gerald Gartlehner, Elizabeth R. Schulman, et al. Drug Therapy for Early Rheumatoid Arthritis: A Systematic Review Update. Agency for Healthcare Research and Quality (AHRQ), 2018. http://dx.doi.org/10.23970/ahrqepccer211.

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