Relevant bibliographies by topics / Drugs design

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Drugs design'

Author: Grafiati
Published: 4 June 2021
Last updated: 30 July 2024

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Journal articles on the topic "Drugs design"

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Bugg, Charles E., William M. Carson, and John A. Montgomery. "Drugs by Design." Scientific American 269, no. 6 (December 1993): 92–98. http://dx.doi.org/10.1038/scientificamerican1293-92.

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BORMAN, STU. "DRUGS BY DESIGN." Chemical & Engineering News Archive 83, no. 48 (November 28, 2005): 28–30. http://dx.doi.org/10.1021/cen-v083n048.p028.

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Krasnopolsky, Yu М. ""QUALITY BY DESIGN" IN LIPOSOMAL DRUGS CREATION." Biotechnologia Acta 13, no. 6 (December 2020): 5–12. http://dx.doi.org/10.15407/biotech13.06.005.

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Nanobiotechnological preparations creation is one of the promising areas of modern pharmacy, since it allows creating products of a qualitatively new level. The procedure development, based on an understanding of the product characteristics and the technological process, confirmed by reliable scientific data. The article is devoted to the pharmaceutical development of liposomal drugs. On the basis of our own experience in the development of liposomal medicinal forms, as well as on the basis of literature data, the main components in their composition were detected and these components impact o
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Snyder, Solomon H. "Pharmacology: Virtuoso design of drugs." Nature 323, no. 6086 (September 1986): 292–93. http://dx.doi.org/10.1038/323292a0.

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Williams, Bryan R. G. "Design of anti-AIDS drugs." Virus Research 19, no. 1 (March 1991): 130. http://dx.doi.org/10.1016/0168-1702(91)90102-2.

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YOKOYAMA, MASAYUKI. "Molecular design of missile drugs." Kagaku To Seibutsu 26, no. 3 (1988): 199–202. http://dx.doi.org/10.1271/kagakutoseibutsu1962.26.199.

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Ferriz, J. M., and J. Vinsova. "Prodrug Design of Phenolic Drugs." Current Pharmaceutical Design 16, no. 18 (June 1, 2010): 2033–52. http://dx.doi.org/10.2174/138161210791293042.

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Isnenia, Isnenia. "Penggunaan Non-Steroid Antiinflamatory Drug dan Potensi Interaksi Obatnya Pada Pasien Muskuloskeletal." Pharmaceutical Journal of Indonesia 6, no. 1 (December 1, 2020): 47–55. http://dx.doi.org/10.21776/ub.pji.2020.006.01.8.

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The main therapy on musculoskeletal patients is the use of non-steroidal anti-inflammatory drugs (NSAIDs) either as monotherapy or in combination with drugs of the same class or pain relievers from other groups. The use of more than one drugs have potentially caused drug-drug interactions that can affect to patient. This study was aimed to describe the patient's sociodemographic (sex, ages) and clinical (numbers of drugs, type of drugs and diagnose) characteristics, as well as to find the correlation between potential drug interactions with these variables. This research was a quantitative stu
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Carlson, Robert. "Supercomputers help design drugs super fast." Inpharma Weekly &NA;, no. 1155 (September 1998): 9–10. http://dx.doi.org/10.2165/00128413-199811550-00019.

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Korcsmáros, Tamás, Máté S. Szalay, Csaba Böde, István A. Kovács, and Péter Csermely. "How to design multi-target drugs." Expert Opinion on Drug Discovery 2, no. 6 (June 2007): 799–808. http://dx.doi.org/10.1517/17460441.2.6.799.

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Dissertations / Theses on the topic "Drugs design"

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Attardo, Giorgio G. (Giorgio Giovanni). "Drug design and synthesis of novel heteroanthracycline antitumor drugs." Thesis, McGill University, 1990. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=74641.

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Novel heteroanthracycline antitumor drugs were designed based on structure activity relationship studies and known mechanisms of drug action. Their preparation required the development of a general synthetic approach.<br>After extensive studies, three methodologies were developed for the general synthetic plan. The first method involved photoenolisation of 2,5-dimethoxybenzaldehyde and SO$ sb2$ entrapment of the o-quinodimethane to give 4,7-dimethoxy-1-hydroxy-1,3-dihydrobenzo(2,3-c) thiophene-2,2-dioxide. This compound served as a general intermediate towards the synthesis of several heteroan
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Zhang, Huarui. "Design, synthesis and activity evaluation of novel exosome inhibitors." HKBU Institutional Repository, 2020. https://repository.hkbu.edu.hk/etd_oa/849.

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Background: Exosomes are extracellular vesicles (EVs) that produced in the endosomal compartment of most eukaryotic cells, and have observed increasing attentions over the past decades. They play important roles in cell- to-cell communications, they can carry varieties of substances, like proteins, nucleic acids and lipids, to the target cells they encounter. These cargos could influence the function of recipient cells. This novel mode of intercellular communication is found to be of critical importance to many cellular activities. However, exosomes are involved in various diseases processes.
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McCallum, Emma Clare. "Adaptive phase II clinical trial design using nonlinear dose-response models." Thesis, University of Cambridge, 2015. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.709013.

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Ma, Haiqiu. "The formulation, manufacture and evaluation of capsules containing freeze-dried aqueous extracts of Leonotis Leonorus or Mentha Longifolia." Thesis, University of the Western Cape, 2006. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_3777_1181559333.

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<p>Leonotis leonorus and Mentha longifolia are two herbs commonly used in South Africa, mostly in oral liquid dosage forms. Several disadvantages are associated with these traditional dosage forms which can perhaps be remedied by using an appropriate oral solid dosage form, provided the actual plant material in the latter still resemble, as closely as possible, the traditionally used material and provide products of suitable pharmaceutical quality. The objectives of this study were to prepare and evaluate the pharmaceutical suitability of the freeze-dried aqueous extracts of Leonotis Leonorus
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Gustafsson, Jörgen. "Synthesis of cyclohexenedicarbaldehydes and studies of their biologic activity." Lund : Organic Chemistry 2, Lund Institute of Technology, University of Lund, 1994. http://books.google.com/books?id=ULpqAAAAMAAJ.

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Moorad, Razia. "Computer-aided drug design and the biological evaluation of anti-cancer drugs." Doctoral thesis, University of Cape Town, 2016. http://hdl.handle.net/11427/20715.

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Computer-aided drug design has become a promising alternative to high-throughput screening by identifying potential hits in silico for in vitro evaluation. In this study a combination of ligand-based and structure-based virtual screening was performed to identify in silico hits. This was based on finding similar inhibitors to 6-amino-4-(4-phenoxyphenylethylamino) quinazoline, a potent inhibitor of the Nuclear Factor kappa B (NF-κB), a transcription factor that has a pivotal role in cancer survival and Pentamidine, an anti-parasitic drug that has recently been demonstrated to possess tumour-kil
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IACUZZI, VALENTINA. "Design of detection systems for the therapeutic drug monitoring of anticancer drugs." Doctoral thesis, Università degli Studi di Trieste, 2020. http://hdl.handle.net/11368/2967986.

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Considerato che la maggior parte dei farmaci antitumorali risulta caratterizzata da un'alta variabilità interindividuale nelle concentrazioni plasmatiche, che si riflette sull'efficacia del trattamento, durante il progetto di dottorato qui descritto sono state sviluppate tecniche per il loro monitoraggio terapeutico (TDM). In primo luogo, è stato sviluppato, validato e cross-validato un metodo LC-MS/MS per la quantificazione di imatinib (IMA) e del suo metabolita attivo, norimatinib (norIMA), in pazienti affetti da tumore stromale gastrointestinale utilizzando la tecnica del dried blood spot (
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Gupta, Sona. "Rational design and delivery of peptide drugs." Thesis, Bangor University, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.323850.

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Soldevila, Barreda Joan Josep. "Design of catalytic organometallic anti-cancer drugs." Thesis, University of Warwick, 2014. http://wrap.warwick.ac.uk/63808/.

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This thesis is concerned with the design of organometallic half sandwich complexes which can catalyse the conversion of oxidised coenzyme nicotinamide adenine dinucleotide to its reduced form. The coenzyme pair NAD+/NADH is involved in many biological processes, such as regulation of the redox balance, and DNA repair. Disturbance of the NAD+/NADH ratio can lead to cell death. In particular, cancer cells are under constant oxidative stress and therefore might be more susceptible to changes in the NAD+/NADH levels. A series of neutral Ru(II) complexes of the type [(η6-arene)Ru(N,N’)(L)] (arene =
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Tripathi, Ashutosh. "DEVELOPMENT OF HINT BASED COMPUTATIONAL TOOLS FOR DRUG DESIGN: APPLICATIONS IN THE DESIGN AND DEVELOPMENT OF NOVEL ANTI-CANCER AGENTS." VCU Scholars Compass, 2009. http://scholarscompass.vcu.edu/etd/1866.

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The overall aim of the research is to develop a computational platform based on HINT paradigm for manipulating, predicting and analyzing biomacromolecular-ligand structure. A second synergistic goal is to apply the above methodology to design novel and potent anti-cancer agents. The crucial role of the microtubule in cell division has identified tubulin as an interesting target for the development of therapeutics for cancer. Pyrrole-containing molecules derived from nature have proven to be particularly useful as lead compounds for drug development. We have designed and developed a series o
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Books on the topic "Drugs design"

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Povl, Krogsgaard-Larsen, Liljefors Tommy, and Madsen Ulf, eds. A Textbook of drug design and development. 2nd ed. Australia: Harwood Academic Publishers, 1996.

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Klesov, A. A. Glycobiology and drug design. Edited by American Chemical Society. Division of Carbohydrate Chemistry. Washington DC: American Chemical Society, 2012.

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Povl, Krogsgaard-Larsen, Strømgaard Kristian, and Madsen Ulf, eds. Textbook of drug design and discovery. 4th ed. Boca Raton: CRC Press/Taylor & Francis, 2010.

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Klesov, A. A. Glycobiology and drug design. Edited by American Chemical Society. Division of Carbohydrate Chemistry. Washington DC: American Chemical Society, 2012.

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Williams, Robert O., Alan B. Watts, and Dave A. Miller. Formulating poorly water soluble drugs. New York, NY: AAPS Press, 2012.

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Fernández, Ariel. Transformative concepts for drug design: Target wrapping. Berlin: Springer, 2010.

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Ward, David J., B.Sc., ed. Peptide pharmaceuticals: Approaches to the design of novel drugs. Milton Keynes: Open University Press, 1991.

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B, Weiner David, and Williams William V, eds. Biological approaches to rational drug design. Boca Raton: CRC Press, 1995.

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Edgar, Kevin J., Charles M. Buchanan, and Thomas Heinze. Polysaccharide materials: Performance by design. Washington DC: American Chemical Society, 2009.

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M, Ottenbrite Raphael, and Kim Sung Wan, eds. Polymeric drugs & drug delivery systems. Lancaster, Pa: Technomic Pub. Co., 2001.

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Book chapters on the topic "Drugs design"

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Folkers, Gerd, Elvan Kut, and Martin Boyer. "Drug Design: Designer Drugs." In X.media.publishing, 53–63. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-69002-3_5.

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Klebe, Gerhard. "How Drugs Act: Concepts for Therapy." In Drug Design, 471–92. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-17907-5_22.

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Wang, Yuxuan, and Ross D. King. "Extrapolation is Not the Same as Interpolation." In Discovery Science, 277–92. Cham: Springer Nature Switzerland, 2023. http://dx.doi.org/10.1007/978-3-031-45275-8_19.

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AbstractWe propose a new machine learning formulation designed specifically for extrapolation. The textbook way to apply machine learning to drug design is to learn a univariate function that when a drug (structure) is input, the function outputs a real number (the activity): F(drug) → activity. The PubMed server lists around twenty thousand papers doing this. However, experience in real-world drug design suggests that this formulation of the drug design problem is not quite correct. Specifically, what one is really interested in is extrapolation: predicting the activity of new drugs with higher activity than any existing ones. Our new formulation for extrapolation is based around learning a bivariate function that predicts the difference in activities of two drugs: F(drug1, drug2) → signed difference in activity. This formulation is general and potentially suitable for problems to find samples with target values beyond the target value range of the training set. We applied the formulation to work with support vector machines (SVMs), random forests (RFs), and Gradient Boosting Machines (XGBs). We compared the formulation with standard regression on thousands of drug design datasets, and hundreds of gene expression datasets. The test set extrapolation metrics use the concept of classification metrics to count the identification of extraordinary examples (with greater values than the training set), and top-performing examples (within the top 10% of the whole dataset). On these metrics our pairwise formulation vastly outperformed standard regression for SVMs, RFs, and XGBs. We expect this success to extrapolate to other extrapolation problems.
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Klebe, Gerhard. "Biologicals: Peptides, Proteins, Nucleotides, and Macrolides as Drugs." In Drug Design, 813–50. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-17907-5_32.

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Nguyen, Jeffrey-Tri, and Yoshiaki Kiso. "Delivery of Peptide Drugs." In Peptide Chemistry and Drug Design, 271–310. Hoboken, NJ, USA: John Wiley & Sons, Inc, 2015. http://dx.doi.org/10.1002/9781118995303.ch8.

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Colman, P. M. "Drugs Targeting Influenza Virus Neuraminidase." In Structure-Based Drug Design, 87–93. Dordrecht: Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-015-9028-0_8.

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Workman, Paul. "Design of Novel Bioreductive Drugs." In New Approaches in Cancer Pharmacology: Drug Design and Development, 63–74. Berlin, Heidelberg: Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-77874-2_7.

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Fischman, A. J., R. H. Rubin, and H. W. Strauss. "In Vivo Imaging in Drug Discovery and Design." In Pharmacokinetics of Drugs, 481–503. Berlin, Heidelberg: Springer Berlin Heidelberg, 1994. http://dx.doi.org/10.1007/978-3-642-78680-8_17.

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Adams, Jerry L., Paul Bamborough, David H. Drewry, and Lisa Shewchuk. "Strategies for Discovering Kinase Drugs." In Gene Family Targeted Molecular Design, 119–57. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470423936.ch5.

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Jacobs, Terry. "Chapter 4 Architectural Design Issues." In Drugs and the Pharmaceutical Sciences, 89–124. 6000 Broken Sound Parkway NW, Suite 300 Boca Raton, FL 33487-2742: CRC Press, 2016. http://dx.doi.org/10.1201/9781315372242-5.

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Conference papers on the topic "Drugs design"

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Rautiola, Davin, and Ronald A. Siegel. "Nasal Spray Device for Administration of Two-Part Drug Formulations." In 2019 Design of Medical Devices Conference. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/dmd2019-3216.

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Intranasal drug delivery is an attractive route to noninvasively achieve a rapid therapeutic effect, avoid first pass metabolism, and bypass the blood brain barrier. However, the types of drugs that can be administered by this route has been limited, in part, by device technology. Herein, we describe a pneumatic nasal spray device that is capable of mixing liquid and solid components of a drug formulation as part of the actuation process during dose administration. The ability to store a nasal spray drug formulation as two separate components can be leveraged to solve a variety of stability is
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Lee, Jae-Hwan, and Ramana M. Pidaparti. "An Implantable Device Design Concept for Ocular Drug Delivery." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80176.

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New drugs for curing eye diseases have been developing for a decade and are very unique for each eye diseases such as glaucoma, cataracts, and age-related macular degeneration (AMD). It is estimated that 1.6 million adults in the US over the age of 50 and above suffer from age-related macular degeneration and about 200,000 cases are diagnosed annually. Worldwide, about 500,000 cases are diagnosed annually [1]. Drugs currently utilized for AMD are delivered via repeated intravitreal injections of the drug into the eye. Risks of repeated intravitreal injections can include intraocular infections
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Groeneveld, Patrick, Rob A. Rutenbar, Jed Pitera, Erik Carlson, and Jinsong Chen. "Oil fields, hedge funds, and drugs." In the 46th Annual Design Automation Conference. New York, New York, USA: ACM Press, 2009. http://dx.doi.org/10.1145/1629911.1630021.

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Mendes, Pedro J., Joa˜o M. M. Sousa, and Joa˜o F. Pinto. "A Virtual Apparatus for Design and Testing of New Drug Formulations and Devices for Inhalation Therapy." In ASME 2007 2nd Frontiers in Biomedical Devices Conference. ASMEDC, 2007. http://dx.doi.org/10.1115/biomed2007-38027.

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Delivery of drugs to the lungs as aerosols is regarded as an excellent route for local or systemic administration of drugs. Aerosols have been used traditionally for treating illnesses of the respiratory tract (e.g. asthma), but new perspectives and needs on inhalation therapy have recently emerged (e.g. insulin). The percentage of drug that reaches the targeted region, the so-called respirable fraction (RF), is in average only 30% of the dose provided to the patient. Thus, the development of more efficient formulations and devices remains an important issue.
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Dolla, William Jacob S., Brian A. Fricke, and Bryan R. Becker. "Auxetic Drug-Eluting Stent Design." In ASME 2006 Frontiers in Biomedical Devices Conference. ASMEDC, 2006. http://dx.doi.org/10.1115/nanobio2006-18035.

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A cardiovascular stent is a cylindrical wire mesh structure that is permanently introduced into an artery during angioplasty (balloon dilatation) to act as a scaffold, thus preventing elastic recoil and/or sudden collapse of the damaged artery. While cardiovascular stents virtually eliminate elastic recoil and/or collapse of the artery, recognition of the stent as a foreign material triggers a human immune system response causing re-closure, or restenosis, of the artery. A recent advancement to counteract restenosis is to employ drug-eluting stents to locally deliver immunosuppressant and anti
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Chebrolu, Anika. "DeepLig: A De-Novo Computational Drug Design Approach to Generate Multi-Targeted Drugs." In 2023 Fifth International Conference on Transdisciplinary AI (TransAI). IEEE, 2023. http://dx.doi.org/10.1109/transai60598.2023.00013.

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Liu, Miao, and Wenjun Wang. "Analysis of antibiotic purchasing service design based on SAPAD-AHP method." In 13th International Conference on Applied Human Factors and Ergonomics (AHFE 2022). AHFE International, 2022. http://dx.doi.org/10.54941/ahfe1002124.

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In the medical field, more than half of people will choose antibiotics for self-medication, they believe that antibiotics can be used for illnesses such as colds and fevers, or even for viral infections, which accelerates bacterial immunity to antibiotics. Misuse of antibiotics is not only unhelpful, but can damage the organism in a variety of ways that can lead to drug resistance, drug toxicity and allergic reactions. Worldwide, hundreds of thousands of people die each year due to bacterial resistance. In China, the use of antibiotics is even higher in outpatient and inpatient settings. The m
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Feng, Yu, Xiaole Chen, and Mingshi Yang. "An In Silico Investigation of a Lobe-Specific Targeted Pulmonary Drug Delivery Method." In 2018 Design of Medical Devices Conference. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/dmd2018-6928.

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Nowadays, “personalized medicine” is starting to replace the current “one size fits all” approach. The goal is to have the right drug with the right dose for the right patient at the right time and location. Indeed, conventional pulmonary drug delivery devices still have poor efficiencies (&lt;25%) for delivering drugs to the lung tumor sites. Major portions of the aggressive medicine deposit on healthy tissue, which causes severe side effects and induces extra health care expenses. Therefore, a new targeted pulmonary drug delivery method is proposed and evaluated using the Computational Fluid
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Sutopo, Hadi, and Ridha Sefina Samosir. "Mobile Multimedia Stop Drugs Tutorial Development." In Proceedings of the 3rd International Conference on Creative Media, Design and Technology (REKA 2018). Paris, France: Atlantis Press, 2018. http://dx.doi.org/10.2991/reka-18.2018.78.

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Zarandi, Marjan Molavi, Rosaire Mongrain, and Olivier F. Bertrand. "Modeling Drug Eluting Stents for Coronary Artery Bifurcation Considering Non-Newtonian Effects." In ASME 2010 3rd Joint US-European Fluids Engineering Summer Meeting collocated with 8th International Conference on Nanochannels, Microchannels, and Minichannels. ASMEDC, 2010. http://dx.doi.org/10.1115/fedsm-icnmm2010-31190.

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Drug Eluting Stents (DES) are commonly used for the treatment of stenotic arteries. Restenosis can be treated by delivering anti-thrombotic and anti-proliferative drugs to the arterial wall. The main mechanism of the drug eluting stent is to allow diffusion of the drug from the coating on the stent, into the arterial wall over a prolonged period of time. Investigation of blood flow hemodynamics and shear stress are of great importance in understanding the transport of drugs through the circulatory systems and predicting the performance of drug eluting stents. While drug eluting stent effective
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Reports on the topic "Drugs design"

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Taufer, Michela, Sandeep Patel, and Narayan Ganesan. Computer-Aided Design of Drugs on Emerging Hybrid High Performance Computers. Fort Belvoir, VA: Defense Technical Information Center, September 2013. http://dx.doi.org/10.21236/ada607433.

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Zhang, Cheng, and Yue Yang. Impact of adaptive design on reducing the duration of clinical trials in rare cancers: a meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, February 2022. http://dx.doi.org/10.37766/inplasy2022.2.0081.

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Review question / Objective: Whether the application of adaptive design in clinical trials of rare cancers can shorten the duration of clinical trials? Condition being studied: Currently, the development of innovative drug products (InMPs) for rare cancers faces many challenges, including the difficulty of enrolling sufficient numbers of patients from small and heterogeneous patient populations for clinical trials, and the significant risks of high financial investment, long development times and potential failure from a pharmaceutical company's perspective for rare cancer drugs due to limited
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Matthews, Lisa, Guanming Wu, Robin Haw, Timothy Brunson, Nasim Sanati, Solomon Shorser, Deidre Beavers, Patrick Conley, Lincoln Stein, and Peter D'Eustachio. Illuminating Dark Proteins using Reactome Pathways. Reactome, October 2022. http://dx.doi.org/10.3180/poster/20221027matthews.

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Diseases are often the consequence of proteins or protein complexes that are non-functional or that function improperly. An active area of research has focused on the identification of molecules that can interact with defective proteins and restore their function. While 22% percent of human proteins are estimated to be druggable, less than fifteen percent are targeted by FDA-approved drugs, and the vast majority of untargeted proteins are understudied or so-called "dark" proteins. Elucidation of the function of these dark proteins, particularly those in commonly drug-targeted protein families,
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Boaden, Dr Bill. Syringe labelling in anaesthesia and critical care areas: review 2022. Association of Anaesthetists of Great Britain and Ireland, September 2022. http://dx.doi.org/10.21466/g.sliaacc.2022.

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This document replaces the Association of Anaesthetists’ previous guidance1 on this topic, following the publication of BS ISO 26825:2020. BS ISO 26825:2020 is the second edition of the standard for user-applied labels for syringes containing drugs used in anaesthesia. It technically revises, cancels and replaces the 2008 first edition. It gives requirements for labels attached to syringes so that the contents can be identified during anaesthesia and covers the colour, size, design and general properties of the label and the typographical characteristics of the wording for the drug name. Its p
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Biazus-Dalcin, Camila, Louise Marryat, Sarah Gray, Andrea Mohan, Senga Robertson-Albertyn, Sreekanth Thekkumkara, Hazel Booth, et al. My data: an animated film, co-produced with people who use drugs. University of Dundee, 2023. http://dx.doi.org/10.20933/100001299.

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This video was co-produced with people on their drug use recovery journey to explore the perceptions of administrative data use for research and to share this information with the wider community. This work was led by members of the Substance Use Research Group (SURG), School of Health Sciences, University of Dundee. This project was funded by Research Data Scotland (RDS), https://www.researchdata.scot/ A film by: Craig Glencross, David Hood, Jade Renton, Maxine Thomson, Ryan Westwood, Stewart Bernard, Sarah Hulin, Robert Doig, Ashley McMaihin and everyone at Restoration Fife who shared their
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Dong, Chengda, Hongshuo Shi, Zhaojun Yan, and Jianmin Liu. Quality of Evidence Supporting the Role of Nonsteroidal Anti-inflammatory Drugs for the Treatment of Anxious Depression: A protocol for Systematic Review and Meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, August 2022. http://dx.doi.org/10.37766/inplasy2022.8.0029.

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Abstract:
Review question / Objective: Population: the participants had anxious depression diagnosed according to any authoritative diagnostic criteria, no restrictions on sex, race, age, onset time, or the source of cases. Intervention: Nonsteroidal Anti-inflammatory Drugs (NSAIDs), including oral and injectable NSAIDs. Comparison: conventional antidepressants. Outcome：effective rate, Hamilton Depression Rating Scale, Hamilton Anxiety Rating Scale, Treatment Emergent Symptom Scale, potential gastrointestinal and neurological adverse events, etc. Study design: Randomized controlled trial. Information so
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Anderson, Burt, Richard Heller, Ed Turos, and Mark Mclaughlin. Drug Discovery, Design and Delivery. Fort Belvoir, VA: Defense Technical Information Center, June 2012. http://dx.doi.org/10.21236/ada563482.

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Marks, James. Structural Basis of EGFR Dimerization for Drug Design. Fort Belvoir, VA: Defense Technical Information Center, September 2000. http://dx.doi.org/10.21236/ada396569.

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Menlove, H. O., D. B. Beddingfield, and M. M. Pickrell. Passive neutron design study for 200-L waste drums. Office of Scientific and Technical Information (OSTI), September 1997. http://dx.doi.org/10.2172/534520.

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Rodgers, L. A. ,. ICP Kaiser Hanford. Shielding design evaluations of concrete-lined drums for RH-Truwaste. Office of Scientific and Technical Information (OSTI), June 1996. http://dx.doi.org/10.2172/657964.

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