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Dissertations / Theses on the topic 'Drugs; GPs'

Author: Grafiati

Published: 4 June 2021

Last updated: 2 February 2022

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1

Carthy, Patricia Ann. "Variation in prescribing in general practice." Thesis, University of Bristol, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.325908.

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2

Watson, Margaret C. "The development, implementation and evaluation of prescribing guidelines in general practice." Thesis, University of Bristol, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.265364.

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3

Chana, Narinder Singh. "Computerised decision support to aid primary care clinicians in the management of specialist drugs : an evaluation of the needs of UK General Practitioners (GPs)." Thesis, King's College London (University of London), 2015. http://kclpure.kcl.ac.uk/portal/en/theses/computerised-decision-support-to-aid-primary-care-clinicians-in-the-management-of-specialist-drugs(d2c0bac5-0d3f-4d75-adbb-fb6ef76e7664).html.

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In the UK since the early 1990s there has been a growing trend for certain hospital initiated specialist drugs to be prescribed by GPs within primary care. GPs have been encouraged to undertake this activity supported by the use of so-called “shared care protocols.” Despite these arrangements this has proven difficult with concerns over the quality and availability of shared care protocols and reported safety related incidents including fatalities linked to the use of certain specialist drugs. GPs have benefited from the complete computerisation of general practice unlike their hospital based

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4

Tandya, Andrian Chemical Sciences &amp Engineering Faculty of Engineering UNSW. "Dense gas particle processing for alternative drug delivery formulations." Awarded by:University of New South Wales. School of Chemical Sciences and Engineering, 2006. http://handle.unsw.edu.au/1959.4/25480.

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Pulmonary and oral drug administrations are usually the preferred methods of delivery of active pharmaceutical ingredients.Generally,pulmonary drug formulations are more attractive compared to oral formulations since they consist of micron-sized powders with high surface area thus having faster onset of action,as well as minimizing the drug dosage and side effects.Oral insulin formulations,if achievable,would provide an alternative to injectable insulin,as the common drawbacks of injectable insulin are the multiple daily injections and the possibility of skin infections at the injection site.

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5

Thigpen, Ashley Lauren Clark C. Randall. "Chromatographic and mass spectral studies on mass equivalent substituted phenethlamines related to MDEA, MDMMA and MBDB." Auburn, Ala., 2006. http://repo.lib.auburn.edu/2006%20Fall/Theses/THIGPEN_ASHLEY_11.pdf.

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6

Adams, Paul Richard. "Evaluation of Welsh drug information services." Thesis, University of London, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.313774.

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7

Hindler, Charles Geoffrey. "Drug misusers and their general practitioners : a survey of the views of drug misusers : training of general practitioners in the management of drug misuse." Thesis, University College London (University of London), 2000. http://discovery.ucl.ac.uk/1348852/.

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Objectives 1. To determine drug misusers' views about their primary health care and their relationship with general practitioners. 2. To undertake a controlled evaluation of small group education of general practitioners in the management of drug misusers. Method 1. Drug misusers attending five treatment services in north east London - a general practice with a special interest in managing drug misuse; a private drug clinic; a community drug team; a drug dependence unit and a street agency - were interviewed using a semi-structured interview and the Social Functioning Questionnaire. 2. All gen

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8

Marsh, Paul Jonathan. "Aspects of porphyrin and phthalocyanine chemistry." Thesis, University of Essex, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.336884.

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9

Mitheo, Yannick K. "Determination of Solute Descriptors for Illicit Drugs Using Gas Chromatographic Retention Data and Abraham Solvation Model." Thesis, University of North Texas, 2015. https://digital.library.unt.edu/ark:/67531/metadc804935/.

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In this experiment, more than one hundred volatile organic compounds were analyzed with the gas chromatograph. Six capillary columns ZB wax plus, ZB 35, TR1MS, TR5, TG5MS and TG1301MS with different polarities have been used for separation of compounds and illicit drugs. The Abraham solvation model has five solute descriptors. The solute descriptors are E, S, A, B, L (or V). Based on the six stationary phases, six equations were constructed as a training set for each of the six columns. The six equations served to calculate the solute descriptors for a set of illicit drugs. Drugs studied are

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10

Mwenesongole, Ellen Musili. "Simultaneous detection of drugs of abuse in waste water using gas chromatography-mass spectrometry." Thesis, Anglia Ruskin University, 2015. http://arro.anglia.ac.uk/550378/.

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Sewage epidemiology is increasingly becoming an alternative method of estimating drug usage and consumption patterns for a given population. With the constant emergence of new psychoactive substances such as cathinones and piperazines, versatile, reliable, specific and sensitive analytical methods are needed for their detection in complex matrices such as waste water. This thesis reports the development of an analytical method based on solid phase extraction, derivatization with pentafluoropropionic anhydride and analysis by gas chromatography-mass spectrometry for the simultaneous analysis of

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11

Song, Shin Miin, and shinmiin@singnet com sg. "Comprehensive two-dimensional gas chromatography (GCxGC ) for drug analysis." RMIT University. Applied Sciences, 2006. http://adt.lib.rmit.edu.au/adt/public/adt-VIT20080627.114511.

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Separation technologies have occupied a central role in the current practices of analytical methods used for drug analysis today. As the emphasis in contemporary drug analysis shifts towards ultra-trace concentrations, the contribution from unwanted matrix interferences takes on greater significance. In order to single out a trace substance with confidence from a rapidly expanding list of drug compounds (and their metabolites) in real complex specimens, analytical technologies must evolve to keep up with such trends. Today, the task of unambiguous identification in forensic toxicology still re

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12

Quinlan, Nathan J. "Gas and particle dynamics in transdermal powdered drug delivery." Thesis, University of Oxford, 1999. http://ora.ox.ac.uk/objects/uuid:f6a9a058-911a-43c5-bc19-95dc866543df.

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Transdermal powdered drug delivery is an emerging technology for the injection of drugs through human skin, in which particles of solid drug are entrained in a high-speed gas flow and directed towards the skin at a high enough velocity to penetrate the outer layer of dead cells. Hand-held devices based on this idea offer a means of safe, painless and effective delivery of many drugs and vaccines. This thesis describes a programme of research into the fluid dynamics which determine the particle velocity distribution, the most important mechanical characteristic of the system, in prototype drug

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13

Barrett, Angela Mary Chemical Sciences &amp Engineering Faculty of Engineering UNSW. "Pharmaceutical processing using dense gas technology." Publisher:University of New South Wales. Chemical Sciences & Engineering, 2008. http://handle.unsw.edu.au/1959.4/41333.

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There exists a demand to re-engineer pre-existing pharmaceuticals to provide improved drug delivery, new dosage forms and increased drug safety and efficacy. Furthermore, the development of novel methods and formulations allows for the patent life of pre-existing drugs to be extended, which has obvious economic benefits for pharmaceutical companies. Dense gas technology provides a means to achieve these aims and to overcome the distinct limitations of traditional technologies. A novel formulation of the antifungal drug itraconazole has been developed using gas antisolvent processes. The new i

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14

Chappell, Colin Graham. "Multidimensional liquid and gas chromatographic methods for veterinary drug analysis." Thesis, University of East Anglia, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.357971.

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15

Martin, Danica Paige. "Optimization of a Method for the Extraction of Drugs of Abuse from Wastewater." Bowling Green State University / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1617014087323429.

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16

Marais, Adriaan Albertyn Scheepers. "Applications of extractive-derivatization sample preparation in a clinical toxicology laboratory setting." Pretoria : [s.n.], 2009. http://upetd.up.ac.za/thesis/available/etd-11252009-235345/.

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17

Ramirez, Alejandro Javier Chambliss C. Kevin Brooks Bryan William. "Determination of pharmaceuticals and personal care products in fish using high performance liquid chromatography-tandem mass spectrometry and gas chromatography-mass spectrometry." Waco, Tex. : Baylor University, 2007. http://hdl.handle.net/2104/5119.

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18

West, Robert E. 1952. "Confirmation of urinary benzodiazepines by gas chromatography/mass spectrometry." Thesis, The University of Arizona, 1989. http://hdl.handle.net/10150/277228.

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A new method is described for the quantitative analysis of urinary benzodiazepines by gas chromatography/mass spectrometry. Development work was aimed at satisfying federal requirements for methods used in forensic urine drug testing which have become the standard in the laboratory industry. Trimethylsilyl (TMS), tert-butyl-dimethylsilyl (TBDMS) and benzophenone derivatives were tested in the development of the new assay. TBDMS derivatives were found to be the most suitable for the analysis of six common benzodiazepine metabolites. Precision for all metabolites tested, as measured by the withi

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19

Sutton, Jonathan T. "Tissue Bioeffects during Ultrasound-Mediated Drug Delivery." University of Cincinnati / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1397234692.

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20

Brown, Stacy D., Mark Rickrode, and Thomas Caldwell. "Determination of JP-8 Components in Soils Using Solid-Phase Microextraction–Gas Chromatography–Mass Spectrometry." Digital Commons @ East Tennessee State University, 2008. https://dc.etsu.edu/etsu-works/5302.

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Jet Propellant-8 (JP-8) is a military fuel associated with a large percentage of chemical exposures documented by the US Department of Defense. A fast and sensitive solid-phase microextraction–gas chromatographic–mass spectrometric method has been developed for the determination of 34 ‘marker compounds’ found in JP-8. Linear ranges were determined for each marker component and precision was measured for these components over four concentrations within each calibration range. The method was applied for the analysis of JP-8 components from soil. The use of SPME over other sample extraction techn

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21

Wang, Zhouxing. "Experimental Determination of L, Ostwald Solubility Solute Descriptor for Illegal Drugs By Gas Chromatography and Analysis By the Abraham Model." Thesis, University of North Texas, 2012. https://digital.library.unt.edu/ark:/67531/metadc115179/.

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The experiment successfully established the mathematical correlations between the logarithm of retention time of illegal drugs with GC system and the solute descriptor L from the Abraham model. the experiment used the method of Gas Chromatography to analyze the samples of illegal drugs and obtain the retention time of each one. Using the Abraham model to calculate and analyze the sorption coefficient of illegal drugs is an effective way to estimate the drugs. Comparison of the experimental data and calculated data shows that the Abraham linear free energy relationship (LFER) model predicts re

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22

White, Ian, and n/a. "Prescribed psychotropic drug use in the Australian Capital Territory : a study of the prevalence and patterns of use in women and the prescribing habits of general practitioners - implications for health education." University of Canberra. Education, 1990. http://erl.canberra.edu.au./public/adt-AUC20061110.130512.

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Psychotropic drugs are mind affecting compounds. They range in type from illegal narcotic analgesics such as heroin, to prescribed major tranquillisers used for treatment of psychotic states, to prescribed minor tranquillisers such as the benzodiazepines, Valium and Mogadon, to the freely available, over the counter drugs, Aspirin and Panadol. Overseas and Australian data show the minor tranquilliser group, benzodiazepines, first introduced on the pharmaceutical scene in the early 1960s, to be the most commonly prescribed psychotropic drugs. Their popularity with medical practitioners as presc

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23

Lam, Un Teng Chemical Sciences &amp Engineering Faculty of Engineering UNSW. "Bioparticle engineering using dense gas technologies." Awarded by:University of New South Wales. Chemical Sciences & Engineering, 2009. http://handle.unsw.edu.au/1959.4/44782.

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The applications of dense gas technology (DGT) in modern particle engineering have shown promising results in producing submicron particles with uniform particle morphology. In this study, two configurations of dense gas antisolvent processes were employed for the micronization, encapsulation and co-precipitation of pharmaceutical compounds. The encapsulation of superparamagnetic iron oxide nanoparticles (SPIONs) by a pH-responsive polymer (Eudragit?? S100) was successfully performed using the supercritical antisolvent (SAS) process. Nanocomposites of less than 200nm in diameter with encapsula

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24

Gandara-Loe, Jesús. "Large versatililty of metal-organic frameworks (MOFs) in gas/liquid adsorption processes." Doctoral thesis, Universidad de Alicante, 2020. http://hdl.handle.net/10045/115204.

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La tesis Doctoral está dividida en dos grandes bloques: el primero relacionado con el estudio estructural y de flexibilidad de distintos "Zeolític imidazolate fremewroks (ZIFs) utilizando distintas técnicas de caracterización de alta resolución y, además, simulación molecular; así como el efecto en la adsorción de distintas moléculas en fase gas. El segundo bloque hace referencia al estudio de MOFs en aplicaciones biomédicas, en específico en el estudio de adsorción y liberación en fase líquida de fármacos para el tratamiento del glaucoma.

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25

Yoganathan, Roshan Bertram Chemical Sciences &amp Engineering Faculty of Engineering UNSW. "Polymer processing using dense gas technology." Awarded By:University of New South Wales. Chemical Sciences & Engineering, 2009. http://handle.unsw.edu.au/1959.4/44499.

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The use of dense CO2 in polymer processing can provide a response to the need for more environmentally-friendly industrial processes. Products with high-purity, sterility, and porosity can be achieved using dense gas technology (DGT). Currently, DGT has been used in different aspects of polymer processing including polymerization, micronization, and impregnation. Due to its solubility in polymers, CO2 can penetrate and plasticize polymers, while impregnating them with low-molecular weight CO2 -soluble compounds. Biodegradable polymers and other medical-grade polymers have benefited from the ap

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26

Torbet, Tyler S. "Analysis of Synthetic Cannabinoids by Direct Analysis in Real Time Quadrupole Time-of-Flight Mass Spectrometry and Gas Chromatography Quadrupole Time-of-Flight Mass Spectrometry." FIU Digital Commons, 2015. http://digitalcommons.fiu.edu/etd/2216.

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The aim of this study was to investigate the utility of direct analysis in real time quadrupole time-of-flight mass spectrometry and gas chromatography quadrupole time-of-flight mass spectrometry in the analysis of 162 different synthetic cannabinoids. Direct analysis in real time quadrupole time-of-flight mass spectrometry is shown to be a rapid and accurate analytical method for synthetic cannabinoids. Spectra can be generated with less than 1.5 ng of the drug in under a minute and be successfully searched against previously generated ESI-QTOF libraries in most cases (118/130 drugs tested) a

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27

Mukherjee, Prithiviraj. "Generation of Drug-loaded Echogenic Liposomes using Microfluidic Hydrodynamic Flow Focusing." University of Cincinnati / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1460731209.

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28

Almarhoon, Zahra M. B. S. "Geographic Variation in the Utilization of Antihyperglycemic Therapies in the U.S. Medicaid Program at State-Level Using Geographic Information System." University of Cincinnati / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1553618550167677.

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29

Hitchcock, Jonathan James. "Automated processing and analysis of gas chromatography/mass spectrometry screening data." Thesis, University of Bedfordshire, 2009. http://hdl.handle.net/10547/134940.

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The work presented is a substantial addition to the established methods of analysing the data generated by gas chromatography and low-resolution mass spectrometry. It has applications where these techniques are used on a large scale for screening complex mixtures, including urine samples for sports drug surveillance. The analysis of such data is usually automated to detect peaks in the chromatograms and to search a library of mass spectra of banned or unwanted substances. The mass spectra are usually not exactly the same as those in the library, so to avoid false negatives the search must repo

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30

Borkar, Sampada N. "Very accurate gas-phase thermochemistry through photoelectron photoion coincidence (PEPICO) spectroscopy." Scholarly Commons, 2013. https://scholarlycommons.pacific.edu/uop_etds/144.

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Five projects are presented here that use Photoelectron Photoion Coincidence (PEPICO) Spectroscopy to determine high-accuracy thermochemical data on small and intermediate size molecules and radicals that are relevant in modeling combustion and atmospheric processes. Some of the experiments were carried out on the laboratory-based Threshold PEPICO (TPEPICO) apparatus which has the advantage of having a low-temperature inlet system and unlimited measurement time, while most of the projects involved the use of the Imaging PEPICO (iPEPICO) apparatus at the Swiss Light Source, which is capable to

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31

Reading, Eamonn. "Structural insights into membrane proteins, membrane protein-lipid interactions and drug metabolites in the gas-phase from ion mobility mass spectrometry." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:f94d42d1-f870-49f9-98b5-42c9b1064e1e.

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Investigating the structures of membrane proteins and their interactions with lipids remains challenging for well-established biophysical techniques. In this thesis the use of mass spectrometry (MS) and ion mobility (IM) spectrometry were explored for the interrogation of membrane proteins, their stoichiometry, stability and interactions with lipids. The techniques used were also applied to the identification of drug metabolites. In the first two chapters reviews of both mass spectrometry methods, and membrane protein biogenesis and membrane protein-lipid interactions are presented. The first

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32

Buen, Zachary. "Establishment of gas-phase thermochemical values of various small organic compounds and oligopeptides." Scholarly Commons, 2016. https://scholarlycommons.pacific.edu/uop_etds/262.

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The thesis describes utilizing mass spectrometry and computational methods to study two groups of molecular systems: small organic molecules and oligopeptides. The gas-phase acidities were measured and the structures of the molecular species were calculated. The small molecules investigated included methylparaben, ibuprofen, and triclosan, all known to have some biological activity. The gas-phase acidity measurements made for these small molecules had the solvent and collisional gas pressures adjusted in order to observe their potential influences. The results obtained provide insight into the

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33

Fiorentin, Taís Regina. "Desenvolvimento e validação de metodologias analíticas confirmatórias para análise de substâncias psicoativas em trânsito." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2017. http://hdl.handle.net/10183/170671.

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A cocaína (COC) é um alcaloide presente nas folhas de espécies do gênero Erytroxylum novagranatense e Erytroxylum coca. Possui grande efeito estimulante sobre o Sistema Nervoso Central (SNC) e por isso é utilizada como droga de abuso. Dentre os principais metabólitos estão a benzoilecgonina (BZE), éster metil anidroecgonina (EMA) e anidroegonina (AEC), sendo que os dois últimos são provenientes de pirólise (consumo do crack através do fumo ou inalação). Ainda, o cocaetileno (CE) é biotransformado após a ingestão conjunta de COC e etanol. O consumo de substâncias psicoativas (SPA), dentre elas

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34

DeGagne, Julia Lynn. "Acid-Base Equilibria in Organic-Solvent/Water Mixtures and Their Relevance to Gas/Particle Partitioning in the Atmosphere and in Tobacco Smoke." PDXScholar, 2016. http://pdxscholar.library.pdx.edu/open_access_etds/2733.

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Acid-base equilibria in organic particulate matter (PM) are poorly understood, but have important implications for air quality and public health. First, acid-base reactions in organic particulate matter affect the gas/particle partitioning of organic compounds in the atmosphere, and these processes are not currently represented in atmospheric and climate change models. Second, the acid-base balance of tobacco smoke affects the amount of nicotine absorbed by the smoker, and a greater understanding of this balance would help to relate cigarette smoke composition to the addictive properties of ci

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35

Lacina, Petr. "Využití plynové chromatografie s hmotnostně spektrometrickou detekcí pro posouzení kontaminace odpadních a povrchových vod rezidui léčiv." Doctoral thesis, Vysoké učení technické v Brně. Fakulta chemická, 2012. http://www.nusl.cz/ntk/nusl-233363.

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This work is based on the current issue of increasing concentrations of pharmaceutical residues in various components of the environment. These new environmental contaminants continuously enter the environment. The most affected environmental component is the aquatic environment. This study is focused on the development and optimization of reliable analytical method, which can determine selected drugs in the aquatic environment (waste waters and surface waters) qualitatively and quantitatively. The target compounds were selected mainly from the group of non-steroidal anti-inflammatory drugs (N

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36

Muccio, Zeland. "Isotope ratio mass spectrometry a rapidly developing tool for forensic samples /." Ohio : Ohio University, 2010. http://www.ohiolink.edu/etd/view.cgi?ohiou1263488205.

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37

Kim, Chi Won. "Synthesis of Porous Coordination Polymers for Controlled Nitric Oxide Release." 京都大学 (Kyoto University), 2016. http://hdl.handle.net/2433/204585.

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38

Macias, Michael S. "The Development of an Optimized System of Narcotic and Explosive Contraband Mimics for Calibration and Training of Biological Detectors." FIU Digital Commons, 2009. http://digitalcommons.fiu.edu/etd/123.

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Current commercially available mimics contain varying amounts of either the actual explosive/drug or the chemical compound of suspected interest by biological detectors. As a result, there is significant interest in determining the dominant chemical odor signatures of the mimics, often referred to as pseudos, particularly when compared to the genuine contraband material. This dissertation discusses results obtained from the analysis of drug and explosive headspace related to the odor profiles as recognized by trained detection canines. Analysis was performed through the use of headspace solid

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39

Wink, Carina S. D. Verfasser], and Hans H. [Akademischer Betreuer] [Maurer. "1,2-diphenylethylamine designer drugs metabolism studies and toxicological analysis using gas chromatography-mass spectrometry and liquid chromatography-mass spectrometry coupled to low and high resolution-mass spectrometry / Carina S. D. Wink. Betreuer: Hans H. Maurer." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2016. http://d-nb.info/1104733323/34.

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40

Glass, Herbert, and Matthias Willner. "Design in globalen Industrien – Ein Blick hinter die Kulissen von Dräger." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2017. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-223797.

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Aus der Einführung: "Dräger ist ein international führendes Unternehmen der Medizin- und Sicherheitstechnik. Das 1889 in Lübeck gegründeten Familienunternehmen besteht in der fünften Generation und hat sich zu einem globalen börsennotierten Konzern entwickelt. „Technik für das Leben“ ist die Leitidee des Unternehmens. Ob im Operationsbereich, auf der Intensivstation, bei der Feuerwehr oder im Rettungsdienst: Dräger-Produkte schützen, unterstützen und retten Leben. Dräger bietet seinen Kunden unter anderem Anästhesie-Arbeitsplätze, Beatmungsgeräte für die Intensiv- und Notfallmedizin, Patienten

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41

Batoon, Patrick Henry M. "Thermochemical differences in lysine and lysine-homolog containing oligopeptides: Determination of basicity and gas-phase structure through mass spectrometry, infrared spectroscopy, and computational chemistry." Scholarly Commons, 2016. https://scholarlycommons.pacific.edu/uop_etds/127.

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The data presented in this thesis is a comprehensive study on the nature of peptide structure and how subtle and systematic changes in sequence and sidechain affect the basicity, ion stability, and conformation of a peptide. The peptides characterized were acetylated polyalanine di-, tri-, and tetra- peptides containing a proton-accepting probe: lysine and or the non-proteinogenic lysine-homologs: ornithine, 2,4-diaminobutyric acid, and 2,3-diaminopropionic acid. Peptides were studied in isomeric pairs for which the basic amino acid was placed closest to the N-terminus or the C-terminus of eac

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42

Glass, Herbert, and Matthias Willner. "Design in globalen Industrien – Ein Blick hinter die Kulissen von Dräger." Technische Universität Dresden, 2016. https://tud.qucosa.de/id/qucosa%3A30291.

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Aus der Einführung: "Dräger ist ein international führendes Unternehmen der Medizin- und Sicherheitstechnik. Das 1889 in Lübeck gegründeten Familienunternehmen besteht in der fünften Generation und hat sich zu einem globalen börsennotierten Konzern entwickelt. „Technik für das Leben“ ist die Leitidee des Unternehmens. Ob im Operationsbereich, auf der Intensivstation, bei der Feuerwehr oder im Rettungsdienst: Dräger-Produkte schützen, unterstützen und retten Leben. Dräger bietet seinen Kunden unter anderem Anästhesie-Arbeitsplätze, Beatmungsgeräte für die Intensiv- und Notfallmedizin, Patienten

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43

Holmgren, Per. "Postmortem toxicology : aspects on interpretation /." Linköping : Univ, 2004. http://www.bibl.liu.se/liupubl/disp/disp2004/med862s.pdf.

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44

Bairros, André Valle de. "Desenvolvimento de métodos analíticos para a identificação de drogas facilitadoras de crime em amostras de urina." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/9/9141/tde-15012015-142703/.

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As drogas facilitadoras de crime (DFC) são uma série de substâncias químicas que permitem o ato sexual e/ou roubo com pouca ou nenhuma resistência da vítima. Benzodiazepínicos, gama-hidroxibutirato (GHB), cetamina e etanol são clássicas DFC, porém outras substâncias também têm sido utilizadas. Devido às diferentes classes de DFC e a necessidade de métodos sensíveis, a determinação dessas substâncias é um desafio aos toxicologistas forenses. A proposta do estudo foi desenvolver métodos analíticos para determinação principais analitos alvos de DFC para benzodiazepínicos, cetamina e GHB em amostr

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45

Hirota, Adriana Sayuri. "Análise do suporte ventilatório mecânico durante anestesia e sua correlação com as complicações pulmonares pós-operatórias: um estudo observacional." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/5/5160/tde-02102014-111242/.

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Introdução: A formação de atelectasia durante a indução anestésica pode ser um dos fatores responsáveis pela ocorrência de complicações pulmonares pós-operatórias (CPP). A aplicação de pressão positiva expiratória ao final da expiração (PEEP), uso criterioso de altas frações inspiradas de oxigênio e a utilização de manobras de recrutamento alveolar no período intra-operatório são recursos utilizados para a prevenção de atelectasia em procedimentos anestésicos. O objetivo deste estudo foi avaliar o modelo de ventilação mecânica adotado em procedimentos anestésicos de longa duração e suas correl

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46

Philipp, Anika-Anina Verfasser], and Hans H. [Akademischer Betreuer] [Maurer. "Studies on the phase I and II metabolism and the toxicological analysis of the alkaloids of the herbal drug of abuse Mitragyna speciosa Korth. (Kratom) using gas chromatography-mass spectrometry and liquid chromatography coupled to low- and high-resolution linear ion trap mass spectrometry / Anika-Anina Philipp. Betreuer: Hans H. Maurer." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2011. http://d-nb.info/1051284848/34.

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Mello, Sueli Moreira de. "Cromatografia em fase gasosa como técnica de triagem para diagnóstico laboratorial das intoxicações agudas por medicamentos depressores do sistema nervoso central (OU) Cromatografia em fase gasosa como técnica de triagem para diagnóstico laboratorial das intoxicações agudas por medicamentos que causam síndrome de depressores do sistema nervoso central." Universidade de São Paulo, 1997. http://www.teses.usp.br/teses/disponiveis/9/9137/tde-23032009-095640/.

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A estatística das principais causas das intoxicações mostra que os depressores do sistema nervoso central (SNC) têm uma participação significativa. No Centro de Controle de Intoxicações da Unicamp, em 1995, 30% das intoxicações foram por medicamentos, sendo a metade por depressores do SNC. A avaliação do paciente intoxicado, freqüentemente inclui, além de exames clínicos, análises laboratoriais para identificação de agentes tóxicos presentes em amostras biológicas. Os procedimentos analíticos com esta finalidade utilizam diversas técnicas, entre elas as cromatográficas. O objetivo do presente

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Grünker, Ronny, Irena Senkovska, Ralf Biedermann, et al. "A highly porous flexible Metal–Organic Framework with corundum topology." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-138599.

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A flexible Metal–Organic Framework Zn4O(BenzTB)3/2 (DUT-13) was obtained by combination of a tetratopic linker and Zn4O6+ as connector. The material has a corundum topology and shows the highest pore volume among flexible MOFs<br>Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich

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Slíva, Karel. "Návrh dvoutlakého horizontálního kotle na odpadní teplo." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2016. http://www.nusl.cz/ntk/nusl-254297.

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The focus of this thesis is a proposal of a horizontal dual-pressure heat recovery steam generator. The introductory part includes thermal calculation, as well as a design of the layout and a design of the heat transfer surfaces and the layout of the boiler. Individual chapters are broken down according to the outline of the proposal for the arrangement of the heating surfaces, according to the parameters of the flue gas and steam. The master thesis contains a scheme of a real heat transfer temperature diagram and it also includes the calculation of connecting and downcomer pipes and drums. Th

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Grünker, Ronny, Irena Senkovska, Ralf Biedermann, et al. "A highly porous flexible Metal–Organic Framework with corundum topology." Royal Society of Chemistry, 2011. https://tud.qucosa.de/id/qucosa%3A27762.

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A flexible Metal–Organic Framework Zn4O(BenzTB)3/2 (DUT-13) was obtained by combination of a tetratopic linker and Zn4O6+ as connector. The material has a corundum topology and shows the highest pore volume among flexible MOFs.<br>Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich.

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