Academic literature on the topic 'Drugs (Synthesis)'

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Journal articles on the topic "Drugs (Synthesis)"

1

Moilanen, E., J. Alanko, E. Seppälä, M. Nissilä, H. Isomakp, and H. Vapaatalo. "Antirheumatic drugs and eicosanoid synthesis." Scandinavian Journal of Rheumatology 17, sup67 (1988): 10–16. http://dx.doi.org/10.3109/03009748809105286.

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2

Zhou, Shiyang, and Gangliang Huang. "Synthesis of anti-allergic drugs." RSC Advances 10, no. 10 (2020): 5874–85. http://dx.doi.org/10.1039/c9ra10659f.

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Histamine is formed by the decarboxylation of histidine catalyzed by enzymes. It is an endogenous biologically active substance involved in multiple complex physiological processes as an important chemical transmitter.
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3

Skachilova, S. Ya, G. A. Ermakova, N. K. Zheltukhin, E. F. Zueva, and N. K. Davydova. "DRUGS DEVELOPED AT «ARC BASS» WITH M.D. MASHKOVSKII LEAD (REVIEW)." Drug development & registration 8, no. 1 (2019): 7–13. http://dx.doi.org/10.33380/2305-2066-2019-8-1-7-13.

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Introduction. There are presented data on drugs development with M.D. Mashkovskii lead. There are given materials on drugs belonging to important pharmacotherapeutic groups of drugs such as generic and original drugs. Original syntheses of famous generic drugs and improved industrial technologies have been developed. The attention is paid to high quality of produced drugs. More than 200 new molecules were synthesized while developing original structures of nitrobenzamide derivatives. The studies of pharmacological and toxicological characteristics have helped to choose and create original anti
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4

Ungvarská Maľučká, Lucia, and Jozef Csöllei. "Design, Synthesis and Biological Activity of New Carbamate Cholinesterase Inhibitors." Chemické listy 116, no. 6 (2022): 372–80. http://dx.doi.org/10.54779/chl20220372.

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The work deals with the design, synthesis and biological activity of new carbamate cholinesterase inhibitors. It is focused on selected syntheses of new carbamate derivatives, which were tested for their anticholinesterase activity against acetylcholinesterase as well as butyrylcholinesterase. Despite various theories in the pathogenesis of Alzheimer's disease, drugs that can inhibit these two enzymes still represent the major approach to the treatment of this neurodegenerative disease. Many of the newly synthesized compounds have unique chemical structure. Recently, the approach to the synthe
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5

Menéndez, J., Marco Leonardi, Verónica Estévez, and Mercedes Villacampa. "The Hantzsch Pyrrole Synthesis: Non-conventional Variations and Applications of a Neglected Classical Reaction." Synthesis 51, no. 04 (2018): 816–28. http://dx.doi.org/10.1055/s-0037-1610320.

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Pyrrole is one of the most important one-ring heterocycles because of its widespread presence in natural products and unnatural bioactive compounds and drugs in clinical use. The preparation of pyrroles by reaction between primary amines, β-dicarbonyl compounds, and α-halo ketones, known as the Hantzsch pyrrole synthesis, is reviewed here for the first time. In spite of its age and its named reaction status, this method has received little attention in the literature. Recent work involving the use of non-conventional conditions has rejuvenated this classical reaction and this is emphasized in
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6

Rode, Haridas B., Dhanaji M. Lade, René Grée, Prathama S. Mainkar, and Srivari Chandrasekhar. "Strategies towards the synthesis of anti-tuberculosis drugs." Organic & Biomolecular Chemistry 17, no. 22 (2019): 5428–59. http://dx.doi.org/10.1039/c9ob00817a.

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In this report, we reviewed the strategies towards the synthesis of anti-tuberculosis drugs. They include semisynthetic approaches, resolution based strategies, microbial transformations, solid phase synthesis, and asymmetric synthesis.
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Di Filippo, Mara, and Marcus Baumann. "Continuous Flow Synthesis of Anticancer Drugs." Molecules 26, no. 22 (2021): 6992. http://dx.doi.org/10.3390/molecules26226992.

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Continuous flow chemistry is by now an established and valued synthesis technology regularly exploited in academic and industrial laboratories to bring about the improved preparation of a variety of molecular structures. Benefits such as better heat and mass transfer, improved process control and safety, a small equipment footprint, as well as the ability to integrate in-line analysis and purification tools into telescoped sequences are often cited when comparing flow to analogous batch processes. In this short review, the latest developments regarding the exploitation of continuous flow proto
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8

Belikov, V. G., and A. G. Kuregyan. "Synthesis of Magnetite Complexes with Drugs." Pharmaceutical Chemistry Journal 38, no. 3 (2004): 153–56. http://dx.doi.org/10.1023/b:phac.0000034306.33479.4d.

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9

Mandala, Devender, Warren A. Thompson, and Paul Watts. "Synthesis routes to anti-HIV drugs." Tetrahedron 72, no. 24 (2016): 3389–420. http://dx.doi.org/10.1016/j.tet.2016.04.075.

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10

Boldyrev, V. V. "Mechanochemical modification and synthesis of drugs." Journal of Materials Science 39, no. 16/17 (2004): 5117–20. http://dx.doi.org/10.1023/b:jmsc.0000039193.69784.1d.

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