Relevant bibliographies by topics / Dual pathology

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Dual pathology'

Author: Grafiati
Published: 4 June 2021
Last updated: 8 February 2022

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Journal articles on the topic "Dual pathology"

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Lesser, Ronald P. "Does Dual Pathology Always Require Dual Resection?" Epilepsy Currents 4, no. 1 (January 2004): 37–38. http://dx.doi.org/10.1111/j.1535-7597.2004.04116.x.

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Szerman, Nestor, Jose Martinez-Raga, Lola Peris, Carlos Roncero, Ignacio Basurte, Pablo Vega, Pedro Ruiz, and Miguel Casas. "Rethinking Dual Disorders/Pathology." Addictive Disorders & Their Treatment 12, no. 1 (March 2013): 1–10. http://dx.doi.org/10.1097/adt.0b013e31826e7b6a.

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Rajurkar, SudayG, MohanD Deshpande, Noaman Kazi, Dhanashree Jadhav, Pallavi Ranadive, and Snehal Ingole. "Dual pathology of mandible." Annals of Maxillofacial Surgery 7, no. 2 (2017): 316. http://dx.doi.org/10.4103/ams.ams_146_16.

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Larner, Andrew J. "Dual pathology or unifying diagnosis?" Journal of the Royal College of Physicians of Edinburgh 49, no. 2 (2019): 145–46. http://dx.doi.org/10.4997/jrcpe.2019.215.

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Yap, Darren, Ashraf Rasheed, and Majid Rashid. "Dual pathology—An unreported case." International Journal of Surgery Case Reports 17 (2015): 164–66. http://dx.doi.org/10.1016/j.ijscr.2015.11.002.

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Mandal, Prakas Kumar, Supriyo Sarkar, Malay Kumar Ghosh, and Maitreyee Bhattacharyya. "Simultaneous dual pathology in lymph node." Mediterranean Journal of Hematology and Infectious Diseases 6, no. 1 (May 31, 2014): e2014036. http://dx.doi.org/10.4084/mjhid.2014.036.

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[Abstract]Tubercuous lymphadenitis and Non Hodgkins’ Lymphoma are common in India. As both diseases can occur in elderly persons there is a definite chance of co-existence of both diseases; but that coexistence has not been reported. Here we present a unique case in an elderly woman who had synchronous double pathology of tuberculosis (TB) and Diffuse Large B cell Lymphoma (DLBCL) of the lymph nodes. Key words:- lymph nodes, tuberculosis (TB), Diffuse Large B cell Lymphoma (DLBCL).
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BHATNAGAR, ASEEM, KISHEN SAWROOP, COL CHANDRA SHEKHAR PANT, and SHYAMAL KUMAR CHAKRAVARTY. "Radionuclide Diagnosis of Dual Abdominal Pathology." Clinical Nuclear Medicine 19, no. 1 (January 1994): 72–73. http://dx.doi.org/10.1097/00003072-199401000-00022.

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Riddiough, Georgina E., Imran Bhatti, and David A. Ratliff. "Acute appendicitis with unusual dual pathology." International Journal of Surgery Case Reports 3, no. 1 (2012): 25–26. http://dx.doi.org/10.1016/j.ijscr.2011.10.008.

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Kirresh, O., U. Srirangalingam, and C. Lunken. "? Dual pathology for pancreatitis in pregnancy." Atherosclerosis Supplements 34 (September 2018): e8. http://dx.doi.org/10.1016/j.atherosclerosissup.2018.07.038.

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Sureka, Binit, and Kalpana Bansal. "Dual Pathology? Autoimmune Pancreatitis and Ductal Adenocarcinoma." American Journal of Roentgenology 205, no. 6 (December 2015): W643. http://dx.doi.org/10.2214/ajr.15.15205.

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Dissertations / Theses on the topic "Dual pathology"

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Hutchinson, Donielle BreAnna. "A Dual Examination of Learning Through Pedagogical Training and Alzheimer's Disease Pathology." BYU ScholarsArchive, 2018. https://scholarsarchive.byu.edu/etd/7569.

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Active learning strategies are important for facilitating deep learning that may be carried throughout life, but which is still finding its way into the college setting. Educators are not often trained in effective learning practices, which reduces the cognitive and proficiency gains of their students. By providing such guidance in the formative years of a teacher’s training, we hypothesize that the learning environment will be greatly enriched and enhanced. On the opposite end of the spectrum of life and cognition, the plague of dementia also warrants examination. Alzheimer’s disease (AD), an incurable neurodegenerative disorder progressing from the medial temporal lobe, is the most common form of dementia diagnosed in people over age 65, afflicting 30-40% of those 85 years and older. Despite its prevalence, effective treatments are limited because the principal causes and triggers of AD are not entirely understood. Growing evidence demonstrates that oxidative stress (OS) is an important factor contributing to the initiation and progression of AD. A key player contributing to this OS is iron, an essential trace mineral which is required for proper neuronal function, but which generates reactive oxygen species during redox transitions. Intracellular labile iron pool (LIP) levels are strictly regulated by proteins such as transferrin (import), ferroportin (export), and ferritin (storage). However, when these proteins become dysregulated, excess iron associates with other proteins such as amyloid beta (Aβ) and tau, aggregations of which are hallmarks of AD. In our hypothetical model, under extensive or prolonged OS, as occurs in AD, much larger Aβ plaques form because the stress does not abate. Hyperphosphorylated tau is the last resort to protect the cell against free iron, and aggregates when the LIP is elevated because neither iron storage in ferritin nor iron export through ferroportin can relieve the neurons of the free iron.
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Mateu, Codina Gerard Àngel. "Factores genéticos en patología dual." Doctoral thesis, Universitat Autònoma de Barcelona, 2019. http://hdl.handle.net/10803/667189.

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El término patología dual describe la coexistencia de una o más enfermedades mentales y trastornos por el uso de sustancias, la cual es muy común y, a menudo, se asocia con una mayor gravedad psiquiátrica y peores condiciones médicas y sociales. Últimamente ha adquirido relevancia la investigación relacionada con el papel del sistema endocannabinoide (eCB) en las bases neurobiológicas de diversas afecciones neuropsiquiátricas, tales como la ansiedad, los trastornos del estado de ánimo o la esquizofrenia, así como los trastornos relacionados con el uso de sustancias. El propósito de este estudio es investigar la asociación entre varios polimorfismos de los genes que codifican algunas proteínas del sistema endocannabinoide (receptor de cannabinoides 1 [CNR1] y amida hidrolasa de ácido graso [FAAH]) de acuerdo con (1) la presencia o ausencia de uso de sustancias trastornos en toda la muestra y (2) según la presencia o ausencia de patología dual en el grupo de sujetos diagnosticados con un trastorno por uso de sustancias. Es un estudio de casos y controles con un tamaño muestral de 675 sujetos, de los cuales 362 son controles (C; individuos sin diagnóstico psiquiátrico) y 313 casos (Cs; individuos con un trastorno por uso de sustancias sin ningún trastorno neuropsiquiátrico comórbido [ TCS] así como individuos con un trastorno de uso de sustancias con una enfermedad neuropsiquiátrica comórbida [PD]). Se compararon los grupos C y Cs y los grupos TCS y PD en base a datos demográficos, antecedentes familiares y personales de trastornos psiquiátricos y trastornos por uso de sustancias (mediante la versión española validada de la Psychiatric Research Interview for Substance and Mental Disorders (PRISM-IV)) y los rasgos de personalidad (evaluada con la versión española del Cloninger’s Temperament and Character Inventory (TCI-R). Se genotiparon 768 polimorfismos de nucleótido único (SNP) que se utilizaron como marcadores genéticos en una aproximación de estudio de gen candidato. Se realizaron análisis estadísticos simples de polimorfismos, genes y haplotipos así como un posterior análisis multivariante. Finalmente se relacionaron los resultados del análisis genético con las características sociodemográficas y clínicas de la muestra. Los sujetos Cs mostraron una mayor prevalencia de antecedentes familiares de enfermedades mentales y trastornos por uso de sustancias, así como una puntuación más baja en dependencia de la recompensa, autodirección, cooperación y autotrascendencia respecto a los sujetos C. Asimismo, los sujetos PD tenían mayor prevalencia de trastornos por consumo de alcohol y cocaína, menor prevalencia de trastornos por consumos de cannabis y mayor prevalencia de antecedentes familiares de enfermedades mentales y trastornos por uso de sustancias frente a los sujetos TCS. Además, los sujetos con TCS obtuvieron puntuaciones más altas en evitación del daño y autotrascendencia, aunque el resultado en autodirección fue significativamente más bajo en los sujetos con PD. Se halló una prevalencia significativa de las variantes AA/AC de SNP rs324420 y TT de SNP rs11576941 (ambos SNP que pertenecen al mismo haplotipo del gen FAAH) en el grupo Cs en el estudio de asociación de CS vs. C. La prevalencia fue también significativa en el caso de la variante TT del SNP rs11576941 que pertenece al gen FAAH en el grupo TCS en el estudio de asociación de TCS frente a C. Además, se detectó un subgrupo de sujetos del grupo de DP con puntuaciones significativamente más bajas en la dimensión de la personalidad evitación del daño que se caracterizan por ser homocigotos GG para el SNP rs806380 del gen CNR1. Esta variación alélica se ha asociado con una mayor sensibilidad para los estímulos positivos y podría representar un marcador endofenotípico para aquellos sujetos con mayor inestabilidad emocional y, por lo tanto, con mayor gravedad clínica potencial.
The term dual pathology describes the coexistence of one or more mental illnesses and substance use disorders which is very common and is often associated with higher psychiatric severity, and worse medical conditions and social status. Likewise, there is now an important body of research on the important role that the endocannabinoid system (eCB) could play on the neurobiological bases of various neuropsychiatric conditions, such as anxiety, mood disorders or schizophrenia, in addition to several substance use disorders. The purpose of this study is to investigate the association between various polymorphisms of the genes encoding for some endocannabinoid system proteins (cannabinoid receptor 1 [CNR1] and fatty acid amide hydrolase [FAAH]) according to (1) the presence or absence of substance use disorders in the whole sample and (2) according to the presence or absence of dual pathology within the group of subjects diagnosed with a substance use disorder. This is a case-control study with a total sample size of 675 subjects, of whom 362 are controls (C; individuals without any psychiatric diagnosis) and 313 cases (Cs; individuals with a substance use disorder without any co-morbid neuropsychiatric condition [TCS] and those individuals with a substance use disorder with co-morbid neuropsychiatric condition [PD]). A comprehensive comparison including demographics, parental and personal background of psychiatric and substance use disorders (according to DSM-IV-R and performed by using the Spanish validated version of Psychiatric Research Interview for Substance and Mental Disorders (PRISM-IV)) and personality characteristics (evaluated using the Spanish version of the Cloninger’s Temperament and Character Inventory (TCI-R))was performed between both Cs and C groups and between TCS and PD groups. 768 single-nucleotide polymorphisms (SNPs) were genotyped wich were used as genetic markers in an approximation of candidate gene study. Simple statistical analysis of polymorphisms, genes and haplotypes and subsequent multivariate analysis were performed. We will relate the results of genetic analysis with sociodemographic and clinical characteristics. The phenotypical results of the comparison between both Cs and C groups showed that Cs subjects had greater prevalence of family background of mental illness and substance use disorders and a lower score on reward dependence, self-directness, cooperativeness and self-transcendence as regarding on personality traits. Likewise, TCS and PD groups contrast show that PD subjects had higher prevalence of alcohol and cocaine use disorders and lower prevalence of cannabis use disorder, as well as a higher prevalence of family background of mental illness and substance use disorders. In addition, TCS subjects had higher score on harm avoidance and self-transcendence but, interestingly, PD subjects score significantly lower on self-directness. We have found a significant prevalence of the AA/AC variants of SNP rs324420 and TT of SNP rs11576941 (both SNPs belonging to the same haplotype of the FAAH gene) in the Cs group in the association study of CS vs. C. The prevalence was significant in the case of the TT variant of the SNP rs11576941 belonging to the FAAH gene in the TCS group in the association study of TCS vs. C. Furthermore, a subgroup of subjects of the PD group with significantly lower scores in the personality dimension harm avoidance that are characterized by being homozygous GG for the SNP rs806380 of the CNR1 gene have been detected. This allelic variation has been associated with a greater sensitivity for positive stimuli and could represent an endophenotypic marker for those subjects with higher emotional instability and, therefore, with greater clinical potential severity.
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Maloney, Shawn. "Dual role of SIRT1 as a regulator of retinal development and a therapeutic target in age-related macular degeneration." Thesis, McGill University, 2011. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=104689.

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Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly in developed countries. Aggressive research is underway to elucidate putative molecular targets for therapy for both the atrophic and neovascular forms of this disease. Current pharmacotherapy is effective in some patients but not sufficient to halt disease progression or repair damage that has already occurred. Drug intervention and retinal cell replacement represent the two most promising potential treatment avenues. The purpose of this thesis was to investigate the role of a recently identified regulator of neural development, SIRT1, in retinogenesis and to further investigate whether pharmacological inhibition of this protein represents a possible treatment option in neovascular AMD. Via immunohistochemistry and immunocytochemistry we evaluated the expression and subcellular localization of SIRT1 and its innate inhibitor, DBC1, in mouse and human fetal and adult retinas. We further studied SIRT1 in mouse- and human-derived retinal progenitor cells, the former being using in small interfering RNA studies. We found SIRT1 to be widely expressed in developing and adult retinas and to be a regulator of key retinal development genes, namely PAX6, Nestin and CRX. Moreover, we found that photoreceptor precursor cells were among the smallest cells in the heterogeneous population of mouse retinal progenitors. Collectively, these results provide the foundation for manipulating SIRT1 expression in small retinal progenitors as a means of increasing the yield of photoreceptors for transplantation in models of retinal degeneration.We further found SIRT1 to be highly expressed in human-derived choroidal neovascular membranes and sought to pharmacologically inhibit its activity via the drug Nicotinamide. We found Nicotinamide to be a potent regulator of angiogenic and hypoxic signaling in a human retinal pigment epithelial cell line at both the protein level using angiogenesis arrays and at the RNA level using whole genome microarrays. These results point to the SIRT1 inhibitor, Nicotinamide, as a possible agent for treatment of neovascular AMD. Further studies of Nicotinamide are warranted in animal models of AMD. To the best of our knowledge, this is the first time that a detailed analysis of SIRT1 as a regulator of both retinal development and choroidal neovascularization has been reported.
La dégénérescence maculaire liée à l'âge (DMLA) est la principale cause de cécité chez les personnes âgées dans les pays développés. Une recherche dynamique est en cours pour élucider des cibles moléculaires potentiels pour le traitement de la dégénérescence à la fois pour la forme atrophique et la forme néovasculaire de cette maladie. L'actuelle pharmacothérapie est efficace chez certains patients mais pas suffisante pour arrêter la progression de la maladie ou la réparation des dommages qui ont déjà eu lieu. La decouverte de nouveaux medicaments et le remplacement de cellules rétiniennes représentent les deux avenues les plus prometteuses de traitements possibles. Le but de cette thèse est d'étudier le rôle d'un régulateur récemment identifié du développement neuronal, SIRT1, dans le developpement de la retine et de rechercher si l'inhibition pharmacologique de cette protéine représente une option de traitement possible dans la DMLA. Via l'immunohistochimie et l'immunocytochimie, nous avons évalué l'expression et la localisation subcellulaire de SIRT1 et de son inhibiteur inné, DBC1, chez la souris et les humains dans les retines fœtales et adultes. Nous avons également étudié SIRT1 dans les cellules souches de la rétine chez la souris et l'homme. Nous avons trouvé SIRT1 largement exprimé dans la rétine en développement et des adultes et à un régulateur de gènes clés du développement de la rétine, à savoir PAX6, Nestin et CRX. En outre, nous avons constaté que les cellules précurseurs des photorécepteurs ont été parmi les plus petites cellules dans la population hétérogène de cellules progénitrices. Collectivement, ces résultats fournissent la base pour la manipulation de l'expression SIRT1 dans les petits progéniteurs rétiniens comme un moyen d'augmenter le rendement des photorécepteurs à la transplantation dans les modèles de dégénérescence rétinienne. Nous avons en outre constaté que SIRT1 est fortement exprimé dans les membranes néovasculaires humaines et avons cherché à inhiber son activité pharmacologique par le nicotinamide. Nous avons trouvé que Nicotinamide est un puissant régulateur de l'hypoxie et de l'angiogenèse au niveau de la protéine et de l'ARN. Ces résultats indiquent que l'inhibiteur de SIRT1, Nicotinamide est un agent possible pour le traitement de la DMLA néovasculaire. D'autres études de la nicotinamide devraient être poursuivit dans des modèles animaux de la DMLA. Au meilleur de notre connaissance, c'est la première fois qu'une analyse détaillée de SIRT1 l'identifie comme un régulateur du développement tant de la rétine et de la néovascularisation choroïdienne.
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Collins, Renee. "An extension of the dual-pathway model of bulimic pathology : examining the mediating effect of sociocultural thin-ideal internalization /." [St. Lucia, Qld.], 2006. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe19766.pdf.

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Hall, Courtney D., M. Sesay, and K. Echt. "Cognitive Training and Motor Dual-Task Ability in Older Adults: A Preliminary Study." Digital Commons @ East Tennessee State University, 2016. https://dc.etsu.edu/etsu-works/2705.

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Veiga, Ana Margarida Rebelo. "O enfermeiro especialista em saúde mental e psiquiátrica no acompanhamento com a pessoa portadora de patologia dual." Master's thesis, Instituto Politécnico de Setúbal. Escola Superior de Saúde, 2019. http://hdl.handle.net/10400.26/29373.

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Mestrado em Enfermagem, Área de especialização: Saúde Mental e Psiquiátrica
Este relatório tem como finalidade descrever o percurso realizado durante os estágios I e estágio final do 2º Mestrado em Enfermagem de Saúde Mental e Psiquiátrica (ESMP), tendo em conta o desenvolvimento e aquisição de competências de Enfermeiro Especialista e Mestre em Saúde Mental e Psiquiátrica. Para a elaboração deste relatório seguiu-se a metodologia de projeto e as suas etapas. A finalidade deste percurso de aprendizagem que foi desenvolvido numa Equipa Técnica Especializada de Tratamento (ETET) da margem sul do Tejo teve como objetivo compreender a importância das intervenções do Enfermeiro Especialista em Enfermagem Saúde Mental e Psi-quiátrica (EEESMP) no acompanhamento com a Pessoa Portadora de Patologia Dual (PPPD), e de adquirir contributos para a realização de um projeto de consulta de enfermagem especiali-zada em Saúde Mental e Psiquiatrica (SMP) para essas pessoas. Na elaboração do presente relatório foi utilizada metodologia científica e como instrumento a revisão Integrativa da literatura, a mesma servirá para uma integração do processo de teori-zação da prática através do recurso às etapas da prática baseada na evidência, respeitante à estrutura do ciclo de estudos conducente ao grau de mestre. As intervenções desenvolvidas basearam-se em competências relacionais e comunicacio-nais fundamentado na Teoria Tidal Model de Phil Barker. Foi desenhada uma proposta de con-sulta de Enfermagem de Saúde Mental e Psiquiatrica, fundamentada no Modelo Tidal. Esta es-trutura-se nas seguintes fases: 1) Avaliação Holística 2) Sessão individual ou Sessão “Um para Um” 3) Avaliação Monitorizada 4) Plano de Segurança Pessoal
This report aims to describe the journey performed during internships I and final stage of the second master`s degree in Mental Health Nursing and Psychiatry (an ESMP), taking into ac-count the development and acquisition of skills of Nurse Specialist and Master´s degree in Men-tal Health and Psychiatry. For the preparation of this report I followed the project methodology and its steps. The purpose of this journey of learning has been developed in a specialized technical Team of treatment (ETET) on the southern shore of Tagus aimed to understand the importance of the contributions of nurses and Mental health nurse specialist Psychiatry (EEESMP) in the follow-up with the person with Dual Pathology (PPPD), and to acquire contributions to the realization of a project of the nursing consultation specializing in Mental Health and Psychiatry (SMP) for these people. At this report we used scientific methodology: Integrative literature review as an instrument to obtain evidence-base outcomes. Serve to integrate the process of theorizing the practice through the use of evidence-based practice steps of Larrabee, concerning the structure of the course leading to the degree of master. The interventions developed were based on relational and communicational skills based on Phil Barker's Tidal Model. A proposal for a Mental Health and Psychiatric Nursing consultation was drawn up, based on this Model, and structured in the following phases: 1. Holistic Assessment 2. Individual Session or “One to One” Session 3. Monitored Evaluation 4. Personal Security Plan
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Vilela, Ana Caroline Marques. "Perfil epidemiológico e psiquiátrico de crianças e adolescentes dependentes químicos hospitalizados no Brasil Central." Universidade Federal de Goiás, 2016. http://repositorio.bc.ufg.br/tede/handle/tede/6376.

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Background: Adolescence is evidenced as one of the age groups the incidence of drug users is high and growing, and this finding suggests the study and research on a variety of questions about the possible relationship between these two phenomena. Attempts to characterize adolescent drug users and the various aspects of its use are of particular importance to contribute to the understanding of substance abuse patterns among young people, as well as provide data for guidance and prevention in the field of problems relating to drugs. Aim: Describe the epidemiology, identify the factors associated with drug use and the presence of dual pathology in adolescents hospitalized in the Midwest of Brazil. Methods: Cross-sectional study of adolescent (10-18 years) drug users hospitalized in Children's Mental Health Association of Goiás between 2010 and 2015. Data were collected retrospectively by chart review. Only patients with chemical dependence on licit or illicit substances as the reason for hospitalization were selected for data collection. Sociodemographic variables and sample characterization, drug usage profile, environmental factors and dual pathologies were collected in a standardized form. Descriptive analysis and association of drug use profile for sex by Chi-square test or Fisher's exact with an alpha of 5% was performed. Results: Among the 214 adolescents studied, 70.2% were male. An early onset of drug use was detected, with a mean age of 13 ± 2 years. Approximately 50% of patients dropped out of school due to drugs and were involved in illegal acts to obtain drugs. The cannabis was the psychoactive substance responsible for most admissions in males, while in females was crack (p = 0.031). Cannabis was the first drug used in life for most individuals, followed by tobacco and alcohol. The main dual pathologies were disruptive behavior disorders (50.0%) and mood disorders (46.7%). Conclusion: This study found a high prevalence of dual disorders, high dropout rates from school due to drug use, involvement in illicit activities to obtain drugs and early onset of substance abuse.
Introdução: A adolescência evidencia-se como uma das faixas etárias cuja incidência de usuários de drogas é alta e crescente, e esta constatação sugere o estudo e pesquisa de uma variedade de questões sobre as possíveis relações entre estes dois fenômenos. Tentativas para caracterizar os adolescentes usuários de drogas bem como os diferentes aspectos relativos ao seu consumo são particularmente importantes para contribuir ao entendimento de padrões de dependência química entre os jovens, assim como também prover dados para a orientação e prevenção no campo dos problemas relativos às drogas Objetivo: Descrever o perfil epidemiológico, identificar os fatores associados ao uso de drogas e a presença de patologias duais em adolescentes hospitalizados no Centro-Oeste Brasileiro. Metodologia: Estudo transversal com adolescentes (10 a 18 anos) usuários de drogas hospitalizados na Associação de Saúde Mental Infantil de Goiás entre 2010 e 2015. Os dados foram obtidos retrospectivamente por meio de revisão de prontuário. Apenas os pacientes que apresentaram dependência química de substâncias lícitas ou ilícitas como motivo de internação foram selecionados para coleta de dados. Variáveis sociodemográficas e de caracterização da amostra, perfil de uso de drogas, fatores ambientais e patologias duais foram coletadas em formulário padronizado. Foi realizada análise descritiva dos dados e de associação do perfil de uso de drogas por sexo pelo teste Qui-quadrado de Pearson ou Exato de Fisher com alfa de 5%. Resultados: Dentre os 214 adolescentes avaliados, 70,2% eram do sexo masculino. Detectou-se início precoce do uso de drogas, com idade média de 13 ± 2 anos. Aproximadamente 50% dos indivíduos abandonaram os estudos devido às drogas e se envolveram com atos ilícitos para obtenção de drogas. A cannabis foi a substância psicoativa responsável pela maioria das internações principal no sexo masculino, enquanto no sexo feminino a principal foi o crack (p=0,031). A cannabis foi a primeira droga utilizada na vida pela maioria dos indivíduos, seguida por tabaco e álcool. As principais patologias duais foram transtornos disruptivos do comportamento (50,0%) e transtornos de humor (46,7%). Conclusão: O presente estudo encontrou alta prevalência de patologias duais, altas taxas de abandono dos estudos devido ao uso de drogas, envolvimento com atos ilícitos para obtenção de drogas e início precoce do abuso de substâncias químicas.
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Sauerbeck, Andrew David. "TRICHLOROETHYLENE EXPOSURE AND TRAUMATIC BRAIN INJURY INTERACT AND PRODUCE DUAL INJURY BASED PATHOLOGY AND PIOGLITAZONE CAN ATTENUATE DEFICITS FOLLOWING TRAUMATIC BRAIN INJURY." UKnowledge, 2011. http://uknowledge.uky.edu/gradschool_diss/133.

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The development of Parkinson's disease (PD) in humans has been linked to genetic and environmental factors for many years. However, finding common single insults which can produce pathology in humans has proved difficult. Exposure to trichloroethylene (TCE) or traumatic brain injury (TBI) has been shown to be linked to PD and it has also been proposed that multiple insults may be needed for disease development. The present studies show that exposure to TCE prior to a TBI can result in pathology similar to early PD and that the interaction of both insults is required for impairment in behavioral function, and cell loss. Following exposure to TCE for 2 weeks there is a 75% impairment in mitochondrial function but it has yet to be shown if the addition of a TBI can make this worse. If the exposure to TCE is reduced to 1 week and combined with TBI a 50% reduction in mitochondrial function is observed following the dual injury which requires both insults. These studies provide further support for the hypothesis that PD may result from a multifactorial mechanism. It had been established that regional differences exist in mitochondrial function across brain regions. The present studies indicate that previous findings are not likely to be the result of differences in individual mitochondria isolated from the cortex, striatum, and hippocampus. Further analysis of the effect of mitochondrial inhibitors on enzyme activity and oxygen consumption reveal that the different regions of the brain are similarly affected by the inhibitors. These results suggest that findings from previous studies indicating regionally specific deficits following systemic toxin exposure, such as with TCE, are not the result of regional differences in the individual mitochondria. Given that TBI results in significant dysfunction, finding effective therapeutics for TBI will provide substantial benefits to individuals suffering an insult. Treatment with Pioglitazone following TBI reduced mitochondrial dysfunction, cognitive impairment, cortical tissue loss, and inflammation. These findings provide initial evidence that treatment with Pioglitazone may be an effective intervention for TBI.
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Barreto, Acevedo Elliot, Zegarra Alicia Becerra, Espinoza Mirla V. Villafuerte, and Rojas Victoria Llaja. "Cirugía de epilepsia en patología dual abordada con estimulación cortical directa y electrocorticografía intraoperatoria. Primer caso en el Hospital Rebagliati." Universidad Peruana Cayetano Heredia (UPCH), 2016. http://hdl.handle.net/10757/615984.

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La coexistencia de esclerosis hipocampal con una lesión extrahipocampal potencialmente epileptógena, situación conocida como patología dual, traza un reto para planificar la cirugía resectiva de epilepsia farmacorresistente. Presentamos un caso de epilepsia focal farmacorresistente asociada a patología dual (esclerosis hipocampal izquierda y gliosis frontal izquierda), abordada con estimulación eléctrica cortical directa y electrocorticografía intraoperatoria, con buenos resultados a corto plazo.
The coexistence of hippocampal sclerosis with a potentially epileptogenic extra hippocampal injury is known as dual pathology, and presents a challenge to resection surgery strategies in cases of drug-resistant epilepsy. We present a case of drug-resistant focal epilepsy associated with dual pathology (left hippocampal sclerosis and left frontal gliosis), treated by means of direct cortical electrical stimulation and intraoperative electrocorticography with good short-term results.
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Hobday, Victoria Louise. "Body image in young people with inflammatory bowel disease, and, Healthcare professionals working with children with a dual diagnosis of type 1 diabetes and coeliac disease." Thesis, University of Birmingham, 2014. http://etheses.bham.ac.uk//id/eprint/5389/.

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Background: Inflammatory Bowel Disease (IBD) includes Crohn’s Disease, Ulcerative Colitis and Indeterminate Colitis, all characterised by chronic, gastrointestinal inflammation. Symptoms can be painful and embarrassing and treatment can result in invasive procedures, side effects and surgery. Qualitative studies suggest that body image may be affected by IBD. Aim: To review published quantitative papers with a measure of body image in children and adolescents with IBD. Method: Electronic databases (PsycInfo, Embase, Medline, Web of Science, CINAHL) were used to systematically review the literature, identifying 19 papers. These papers were reviewed using a critical appraisal tool. Results: The review discusses themes relating to body image including: type of IBD diagnosis; age at diagnosis; severity of symptoms; gender and treatment. Trends in body image are similar to healthy peers, particularly for those with mild or no symptoms. IBD can predispose the young person to risk factors, increasing their vulnerability to poor body image, including delayed growth, increase in severe physical symptoms and intrusive or demanding treatments. Conclusion: Routine assessment of psychosocial factors, including body image, for young people with IBD is recommended. This review highlights methodological limitations in the current body of evidence, calling for further research to improve understanding of this area. Background: The psychosocial issues and challenges for young people with a dual diagnosis of type 1 diabetes and coeliac disease and their parents have been explored and uncertainties within screening and diagnostic processes are documented. However, the experiences of healthcare professionals (HCPs) working with this group has to date remained unexplored. Method: Twelve HCPs (doctors, nurses, dieticians) working in this field from three paediatric teams were interviewed about their experiences. Transcripts were analysed using Interpretative Phenomenological Analysis. Results: Three superordinate themes emerged: ‘Connection and burden’; ‘Diagnoses together, but separate and uneven’; and ‘Sitting with certain uncertainty and complexity’. These represent participants‘ connection to the experience of patients and adding to their burden; a sense of disparity in managing the two conditions; uncertainty and complexity with the dual diagnosis, and a repertoire of coping strategies utilised. Positive aspects of the role (making a difference, improving health and reducing risk) along with coping strategies are likely to buffer the challenges of working with this client group. Conclusion: Recommendations include a dual review clinic and further support for staff. Additional research on medical and psychosocial aspects of this dual diagnosis is needed to develop services to support both patients and HCPs.
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Books on the topic "Dual pathology"

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Razumova, Tat'yana, Natal'ya Spiridonova, Irina Durakova, Sergey Taltynov, Ekaterina Mayer, Svetlana Sotnikova, Anatoliy Zhukov, et al. Personnel management in Russia: vector of humanization. Book 7. ru: INFRA-M Academic Publishing LLC., 2020. http://dx.doi.org/10.12737/1060850.

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The monograph contains the results of studies concerning: first, the evolution of ideas and practice of humanization in the personnel policy of the state; second, the implementation of the principles of humanization in work with the personnel of economic subjects: talent management, renewal of working capacity of older workers, building a dual career, building a strong corporate culture, the development of the additional professional education system; thirdly, problems related to industry characteristics personnel work, drawing on international experience of vocational rehabilitation and employment promotion of persons with disabilities, concerning the roles of personal characteristics and character pathology in the context of modern life; fourth, approaches to the weakening of the precarization of labor, University teachers, gender discrimination in the labour market, working with a "toxic" staff, to prevent stress in the workplace. Addressed to scientific-pedagogical and practical workers in the sphere of work with personnel; graduate students, undergraduates, students, professional interests which relate to issues of personnel management.
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Kirollos, Ramez, Adel Helmy, Simon Thomson, and Peter Hutchinson, eds. Oxford Textbook of Neurological Surgery. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780198746706.001.0001.

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Neurosurgery is a rapidly developing and technically demanding branch of surgery that requires a detailed knowledge of the basic sciences and a thorough clinical approach. The Oxford Textbook of Neurological Surgery is an up-to-date, objective, and readable text that covers the full scope of neurosurgical practice. Each section takes a dual approach with ‘generic surgical management’ chapters that focus on specific clinical problems facing the neurosurgeon (e.g. sellar/suprasellar tumour, intradural spina tumours, and others) and ‘pathology-specific’ chapters (e.g. glioma, meningeal tumours, scoliosis and spinal deformity, aneurysm, and others). Where appropriate, this division provides the reader with easily accessible information for both clinical problems which present in a regional fashion and specific pathologies. The generic chapters cover aspects such as operative approaches, neuroanatomy, and nuances.
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Chong, Ji Y., and Michael P. Lerario. Progressive Gait Dysfunction. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190495541.003.0034.

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Spinal vascular malformations are rare, with dural arteriovenous fistulas (AVFs) accounting for the majority of the pathology. Unlike spinal arteriovenous malformations, which cause abrupt neurological change as a result of hemorrhage, spinal dural AVFs tend to result in a progressive myelopathy through venous congestion and cord edema. If diagnosed and treated early with endovascular embolization or microsurgery, some deficits may be reversible.
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Barsoum, Rashad S. Schistosomiasis. Edited by Vivekanand Jha. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0194_update_001.

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The urinary system is the primary target of Schistosoma haematobium infection, which leads to granuloma formation in the lower urinary tract that heals with fibrosis and calcification. While the early lesions may be associated with distressing acute or subacute symptoms, it is the late lesions that constitute the main clinical impact of schistosomiasis. The latter include chronic cystitis, ureteric fibrosis, ureterovesical obstruction or reflux which may lead to chronic pyelonephritis. Secondary bacterial infection and bladder cancer are the main secondary sequelae of urinary schistosomiasis.The kidneys are also a secondary target of S. mansoni infection, attributed to the systemic immune response to the parasite. Specific immune complexes are responsible for early, often asymptomatic, possibly reversible, mesangioproliferative lesions which are categorized as ‘class I’. Subsequent classes (II–VI) display different histopathology, more serious clinical disease, and confounding pathogenic factors. Class II lesions are encountered in patients with concomitant salmonellosis; they are typically exudative and associated with acute-onset nephrotic syndrome. Classes III (mesangiocapillary glomerulonephritis) and IV (focal segmental sclerosis) are progressive forms of glomerular disease associated with significant hepatic pathology. They are usually associated with immunoglobulin A deposits which seem to have a significant pathogenic role. Class V (amyloidosis) occurs with long-standing active infection with either S. haematobium or S. mansoni. Class VI is seen in patients with concomitant HCV infection, where the pathology is a mix of schistosomal and cryoglobulinaemic lesions, as well as amyloidosis which seems to be accelerated by the confounded pathogenesis.Early schistosomal lesions, particularly those of the lower urinary tract, respond to antiparasitic treatment. Late urological lesions may need surgery or endoscopic interventions. As a rule, glomerular lesions do not respond to treatment with the exception of class II where dual antiparasitic and antibiotic therapy is usually curative. Patients with end-stage kidney disease may constitute specific, yet not insurmountable technical and logistic problems in dialysis or transplantation. Recurrence after transplantation is rare.
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Paech, Michael J., and Patchareya Nivatpumin. Postdural puncture headache. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198713333.003.0027.

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Postdural puncture headache (PDPH) may follow either deliberate or unintentional (accidental) penetration of the interdigitating meninges, the dura and arachnoid mater. It is one of the most common and clinically important complications of regional anaesthesia and analgesia in the obstetric population. The headache develops as a consequence of cerebrospinal fluid loss, low intracranial pressure and cerebrovascular changes in the upright position and can prove debilitating. The diagnosis is clinical, making thorough assessment and regular review all the more important, to revise treatment plans, exclude rare serious pathology such as subdural haematoma, and avoid misdiagnosis. This chapter reviews the pathophysiology, incidence, risk factors (needle, technical and patient related), features, natural history, diagnosis, and management of PDPH. High level evidence supports prevention by using small gauge, non-cutting spinal needles, but other preventative strategies against either unintentional dural puncture or PDPH are poorly supported. The absent or poor efficacy of measures such as bed rest, hydration, cerebral vasoconstrictor therapy, epidural or intrathecal saline injection, intrathecal catheter placement or prophylactic epidural blood patch, is noted. Validation of better evidence supporting epidural morphine or intravenous cosyntropin is required. Symptomatic treatment of PDPH is also unreliable. Very limited evidence that requires substantiation supports a modest benefit from caffeine, gabapentinoids or intravenous hydrocortisone. The intervention of epidural blood patch is highly likely to relieve post-spinal PDPH, but only completely resolves epidural needle-induced PDPH in 30–50% of cases. Much detail about EBP remains undetermined, but delayed intervention and injection of approximately 20 mL of autologous blood appear appropriate.
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Salton, Herman T. Dangerous Diplomacy. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780198733591.001.0001.

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This book assesses the role of the UN Secretariat in the Rwandan genocide. With the help of new sources, including the personal diaries and private papers of the late Sir Marrack Goulding, it situates the Rwanda operation within the context of bureaucratic friction existing at Headquarters in the early 1990s between the Department of Political Affairs (DPA) and the Department of Peacekeeping Operations (DPKO). The book argues that these units clashed not only over resources (a classic symptom of bureaucratic pathology) but also over the scope of peacekeeping and the role of the Secretary-General (SG) within it. This rivalry also reflected a split between a strong-willed SG determined to leave his mark on international affairs and to use his ‘political’ department independently of states, and Washington and the politico-military apparatus of the Pentagon, which in Somalia, Rwanda, Bosnia, and Haiti found itself increasingly at odds with Boutros-Ghali. Although the book looks at how this bureaucratic and power-political confrontation impacted on the Rwanda mission, it identifies the conceptual reasons for the DPA–DPKO split in the grey area that separates peacebuilding and peacekeeping. The difficulty of distinguishing these two key UN functions, coupled with the creative tension between SGs and states, explains why six decades after the birth of the UN, it has still not been possible to demarcate the exact roles of DPA and DPKO. Far from being dull and irrelevant, the book concludes that the UN bureaucracy is an intriguing barometer of the role of the Secretary-General in world politics.
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Book chapters on the topic "Dual pathology"

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Guan-Hui, Dai, G. Mur, and D. Boubals. "A New Disease Reaction Type in Dual Culture of Plasmopara Viticola and in Vitro Plantlets of Grapevines (Vitis SP.)." In Developments in Plant Pathology, 459. Dordrecht: Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-1737-1_139.

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Yu, Hong, Sen Zha, Yubin Huangfu, Chen Chen, Meng Ding, and Jiangyun Li. "Dual Attention U-Net for Multi-sequence Cardiac MR Images Segmentation." In Myocardial Pathology Segmentation Combining Multi-Sequence Cardiac Magnetic Resonance Images, 118–27. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-65651-5_11.

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Li, Feiyan, and Weisheng Li. "Dual-Path Feature Aggregation Network Combined Multi-layer Fusion for Myocardial Pathology Segmentation with Multi-sequence Cardiac MR." In Myocardial Pathology Segmentation Combining Multi-Sequence Cardiac Magnetic Resonance Images, 146–58. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-65651-5_14.

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Smith, A. S. J., J. Buckell, P. Wheat, and R. Longo. "Hierarchical Performance and Unobservable Heterogeneity in Health: A Dual-Level Efficiency Approach Applied to NHS Pathology in England." In Productivity and Efficiency Analysis, 119–43. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-23228-7_8.

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Xue, Yunzhe, Yanan Yang, Fadi G. Farhat, Frank Y. Shih, Olga Boukrina, A. M. Barrett, Jeffrey R. Binder, William W. Graves, and Usman W. Roshan. "Brain Tumor Classification with Tumor Segmentations and a Dual Path Residual Convolutional Neural Network from MRI and Pathology Images." In Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries, 360–67. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-46643-5_36.

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Harms, Fabrice. "Chapter 16 Dual-Modality Full-Field Optical Coherence and Fluorescence Sectioning Microscopy: Toward All Optical Digital Pathology on Freshly Excised Tissue." In Handbook of Full-Field Optical Coherence Microscopy, 565–94. Penthouse Level, Suntec Tower 3, 8 Temasek Boulevard, Singapore 038988: Pan Stanford Publishing Pte. Ltd., 2016. http://dx.doi.org/10.1201/9781315364889-17.

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Aull, S., C. Baumgartner, G. Wiest, I. Podreka, G. Lindinger, K. Hittmaier, A. Olbrich, K. Novak, and L. Deecke. "Duale Pathologie — arterio-venöse Malformationen und Hippokampusatrophie." In Topographische Diagnostik des Gehirns, 290–93. Vienna: Springer Vienna, 1995. http://dx.doi.org/10.1007/978-3-7091-9415-7_74.

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D’Aliberti, Giuseppe, Giuseppe Talamonti, Davide Boeris, Francesco M. Crisà, Alessia Fratianni, Roberto Stefini, Edoardo Boccardi, and Marco Cenzato. "Intracranial Dural Arteriovenous Fistulas: The Sinus and Non-Sinus Concept." In Acta Neurochirurgica Supplement, 113–22. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-63453-7_17.

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AbstractIntroduction: Dural arteriovenous fistulas (dAVFs) account for 10–15% of all intracranial arteriovenous lesions. Different classification strategies have been proposed in the course of the years. None of them seems to guide the treatment strategy. Objective: We expose the experience of the vascular group at Niguarda Hospital and we propose a very practical classification method based on the location of the shunt. We divide dAVF in sinus and non-sinus in order to simplify our daily practice, as this classification method is simply based on the involvement of the sinuses. Material and Methods: 477 intracranial dural arteriovenous fistulas have been treated. 376 underwent endovascular treatment and 101 underwent surgical treatment. Cavernous sinus DAVFs and Galen ampulla malformations have been excluded from this series as they represent a different pathology per se. 376 dAVFs treated by endovascular approach: 180 were sinus and 179 were non-sinus. 101 dAVFs treated with surgical approach: 15 were sinus and 86 were non-sinus. Discussion: Of the 477 intracranial dAVF the recorded mortality and severe disability was 3% and morbidity less than 4%. All patients underwent a postoperative DSA with nearly 100% of complete occlusion of the fistula. At a mean follow-up of 5 years in one case there was a non-sinus fistula recurrence, due to the presence of a partial clipping of “piè” of the vein. Conclusions: The sinus and non-sinus concept has guided our institution for years and has led to good clinical results. This paper intends to share this practical classification with the neurosurgical community.
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"Dual pathology." In Nail in Differential Diagnosis, 129–35. CRC Press, 2006. http://dx.doi.org/10.1201/b14866-9.

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Sinha, O. K. "Dual Culture: Fungi." In Molecular Methods in Plant Pathology, 289–300. CRC Press, 2017. http://dx.doi.org/10.1201/9780203746523-20.

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Conference papers on the topic "Dual pathology"

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Lang, Nathan, Devansh Saxena, Tina Yen, Julie Jorns, Bing Yu, and Dong Hye Ye. "Breast cancer magnification-independent multi-class histopathology classification using dual-step model." In Digital and Computational Pathology, edited by John E. Tomaszewski and Aaron D. Ward. SPIE, 2021. http://dx.doi.org/10.1117/12.2582299.

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Guzman, Francisco, and Jennifer K. Barton. "Dual OCT/spectroscopy system for identification of vascular pathology." In BiOS 2001 The International Symposium on Biomedical Optics, edited by R. Rox Anderson, Kenneth E. Bartels, Lawrence S. Bass, C. Gaelyn Garrett, Kenton W. Gregory, Abraham Katzir, Nikiforos Kollias, et al. SPIE, 2001. http://dx.doi.org/10.1117/12.427827.

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Esposti, Walter, and Italo Meroni. "Nondestructive testing: use of IR and acoustics methods in buildings pathology." In SPIE's 1995 Symposium on OE/Aerospace Sensing and Dual Use Photonics, edited by Sharon A. Semanovich. SPIE, 1995. http://dx.doi.org/10.1117/12.204879.

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Coratu, Ana Maria, Gerard Angel Mateu Codina, Rebeca Alayon Santana, Rosa Blanca Sauras Quetcuti, Marta Torrens Melich, and Lina Maria Oviedo Penuela. "PSYCHOTIC DISORDERS IN PATIENTS WITH SUBSTANCE USE A descriptive study of patients attended in a Dual Pathology Department." In 22° Congreso de la Sociedad Española de Patología Dual (SEPD) 2020. SEPD, 2020. http://dx.doi.org/10.17579/sepd2020p044.

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a) Objectives: This study analyses the characteristics and prevalence of psychotic disorders in patients with substance use, that needed medical and psychiatric care in a Dual Pathology Department during a 3 years period. b) Background and aims: The strong comorbidity between substance use and psychotic disorders has been deeply studied in recent literature. The aim of this study is to analyse the characteristics of the psychotic episode (primary or drug-induced), the predominant substance of use and the age of onset of consumption, as well as some sociodemographic characteristics in these patients. c) Materials and methods After a bibliographic review of recent literature, we realize a descriptive study of psychotic disorders and substance use from a total of 531 hospitalized patients during a 3 years period, using SPSS for Windows 20.0 database for statistic results. d) Results: In this study we can observe a predominant percentage of males with an average age of 36 years old, around 50% psychotic disorders out of total number of patients with a predominant type of primary psychosis and a high prevalence of cocaine (18% of total patients), alcohol (16%) and cannabis (8%) use and also an early age of onset of problematic consumption (15 years old for alcohol, 16 years old for cannabis and 21 years old for cocaine). e) Conclusions: The result of this study approach the current literature data about psychotic disorders and substance use and underlines the importance of a correct and early diagnosis in patients with a serious mental illness.
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Torres, Veronica C., Cynthia Li, Lagnojita Sinha, Jovan G. Brankov, and Kenneth M. Tichauer. "Demonstration of Dual Channel Fluorescent Optical Projection Tomography to Guide Lymph Node Pathology." In Optical Tomography and Spectroscopy. Washington, D.C.: OSA, 2018. http://dx.doi.org/10.1364/ots.2018.oth4d.7.

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Hu, Bihe, Guang Li, Andrew B. Sholl, and J. Quincy Brown. "Dual-view Inverted Selective Plane Illumination Microscopy for Accurate 3D Digital Pathology on Large Specimens." In Novel Techniques in Microscopy. Washington, D.C.: OSA, 2019. http://dx.doi.org/10.1364/ntm.2019.nt3c.3.

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Hu, Bihe, Daniel Bolus, and Jonathon Brown. "Dual-view inverted selective plane illumination microscopy (diSPIM) with improved background rejection for accurate 3D digital pathology." In Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XXV, edited by Thomas G. Brown, Carol J. Cogswell, and Tony Wilson. SPIE, 2018. http://dx.doi.org/10.1117/12.2290785.

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Wang, Danni, Ye Chen, Daphne Meza, Yu Wang, and Jonathan T. C. Liu. "Development and optimization of a line-scanned dual-axis confocal (LS-DAC) microscope for high-speed pathology." In SPIE Translational Biophotonics, edited by Tomasz S. Tkaczyk. SPIE, 2014. http://dx.doi.org/10.1117/12.2057743.

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Wang, Shaobai, Won Man Park, and Guoan Li. "Noninvasive Prediction of the In Vivo Forces on the Lumbar Intervertebral Discs: A Validation Study." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53141.

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Evaluation of the forces on the lumbar intervertebral discs (IVDs) is critically important since it closely relates to biomechanics, pathology, prosthesis design and tissue engineering. It remains a big challenge to noninvasively predict the in vivo forces on the IVD. Using our previously established dual fluoroscopic imaging system (DFIS) [1], motion of the vertebrae can be accurately obtained. We proposed to use the kinematics from DFIS as inputs into FE model to calculate the forces on the IVD. In this study, we validated the technique by testing an IVD on a 6DOF robotic system under applied loads and under DFIS. A subject specific FE model of IVD was built. Forces and moments were predicted and compared to the applied loads.
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Suzuki, Kenji, Samuel G. Armato III, Roger Engelmann, Philip Caligiuri, and Heber MacMahon. "Temporal subtraction of 'virtual dual-energy' chest radiographs for improved conspicuity of growing cancers and other pathologic changes." In SPIE Medical Imaging, edited by Ronald M. Summers and Bram van Ginneken. SPIE, 2011. http://dx.doi.org/10.1117/12.878662.

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