Journal articles: 'Dual pathology'

1

Lesser, Ronald P. "Does Dual Pathology Always Require Dual Resection?" Epilepsy Currents 4, no. 1 (January 2004): 37–38. http://dx.doi.org/10.1111/j.1535-7597.2004.04116.x.

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Szerman, Nestor, Jose Martinez-Raga, Lola Peris, Carlos Roncero, Ignacio Basurte, Pablo Vega, Pedro Ruiz, and Miguel Casas. "Rethinking Dual Disorders/Pathology." Addictive Disorders & Their Treatment 12, no. 1 (March 2013): 1–10. http://dx.doi.org/10.1097/adt.0b013e31826e7b6a.

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Rajurkar, SudayG, MohanD Deshpande, Noaman Kazi, Dhanashree Jadhav, Pallavi Ranadive, and Snehal Ingole. "Dual pathology of mandible." Annals of Maxillofacial Surgery 7, no. 2 (2017): 316. http://dx.doi.org/10.4103/ams.ams_146_16.

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Larner, Andrew J. "Dual pathology or unifying diagnosis?" Journal of the Royal College of Physicians of Edinburgh 49, no. 2 (2019): 145–46. http://dx.doi.org/10.4997/jrcpe.2019.215.

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Yap, Darren, Ashraf Rasheed, and Majid Rashid. "Dual pathology—An unreported case." International Journal of Surgery Case Reports 17 (2015): 164–66. http://dx.doi.org/10.1016/j.ijscr.2015.11.002.

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Mandal, Prakas Kumar, Supriyo Sarkar, Malay Kumar Ghosh, and Maitreyee Bhattacharyya. "Simultaneous dual pathology in lymph node." Mediterranean Journal of Hematology and Infectious Diseases 6, no. 1 (May 31, 2014): e2014036. http://dx.doi.org/10.4084/mjhid.2014.036.

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[Abstract]Tubercuous lymphadenitis and Non Hodgkins’ Lymphoma are common in India. As both diseases can occur in elderly persons there is a definite chance of co-existence of both diseases; but that coexistence has not been reported. Here we present a unique case in an elderly woman who had synchronous double pathology of tuberculosis (TB) and Diffuse Large B cell Lymphoma (DLBCL) of the lymph nodes. Key words:- lymph nodes, tuberculosis (TB), Diffuse Large B cell Lymphoma (DLBCL).

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BHATNAGAR, ASEEM, KISHEN SAWROOP, COL CHANDRA SHEKHAR PANT, and SHYAMAL KUMAR CHAKRAVARTY. "Radionuclide Diagnosis of Dual Abdominal Pathology." Clinical Nuclear Medicine 19, no. 1 (January 1994): 72–73. http://dx.doi.org/10.1097/00003072-199401000-00022.

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Riddiough, Georgina E., Imran Bhatti, and David A. Ratliff. "Acute appendicitis with unusual dual pathology." International Journal of Surgery Case Reports 3, no. 1 (2012): 25–26. http://dx.doi.org/10.1016/j.ijscr.2011.10.008.

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Kirresh, O., U. Srirangalingam, and C. Lunken. "? Dual pathology for pancreatitis in pregnancy." Atherosclerosis Supplements 34 (September 2018): e8. http://dx.doi.org/10.1016/j.atherosclerosissup.2018.07.038.

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Sureka, Binit, and Kalpana Bansal. "Dual Pathology? Autoimmune Pancreatitis and Ductal Adenocarcinoma." American Journal of Roentgenology 205, no. 6 (December 2015): W643. http://dx.doi.org/10.2214/ajr.15.15205.

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Gavidi, Ratu Osea, Benedict Seo, and Norman Firth. "Dual pathology: a case involving the jaws." Pathology 44 (2012): S13. http://dx.doi.org/10.1016/s0031-3025(16)32637-x.

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Cañas Fraile, S., A. Gómez Peinado, and P. Cano Ruíz. "Evolution of Bipolar Disorder in Dual Pathology." European Psychiatry 30 (March 2015): 1125. http://dx.doi.org/10.1016/s0924-9338(15)30890-7.

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Fisher, Robert S., and David Blum. "Epilepsy surgery where there is dual pathology." Lancet 354, no. 9175 (July 1999): 267–68. http://dx.doi.org/10.1016/s0140-6736(99)00180-4.

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Lopera Lopera, Ramon E., Andrea Rincón Hurtado, Veronica Vargas Gonzalez, Juan F. Arbeláez, Guillermo A. Castaño Pérez, Jesy C. Buitrago Salazar, and Silvia Gaviria Arbeláez. "Cognitive Impairment in Patients With Dual Pathology." Addictive Disorders & Their Treatment 18, no. 1 (March 2019): 53–57. http://dx.doi.org/10.1097/adt.0000000000000150.

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Ibañez, Ángela. "IMPULSIVITY, GENDER DIFFERENCES AND DUAL PATHOLOGY IN." Revista de Patología Dual 1, no. 2 (September 2, 2014): 1–7. http://dx.doi.org/10.17579/revpatdual.01.8.

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Silvia, C. F., M. D. Sánchez García, A. Gómez Peinado, and P. Cano Ruiz. "Evolution of bipolar disorder in dual pathology." European Psychiatry 33, S1 (March 2016): S340. http://dx.doi.org/10.1016/j.eurpsy.2016.01.1195.

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IntroductionThe substance use is common among people with a diagnosis of bipolar disorder. In addition, alcoholism and bipolar disorder coexist with a high frequency. This association is higher in men than in women, and this consumption is the factor that most strongly influences the hospitalization.ObjectivesTo analyze the clinical, epidemiological, diagnostic approach and evolution of bipolar disorder and alcoholism.MethodsReview of the subject on recent articles of alcoholism in bipolar disorder.ResultsThe stages of mania associated with alcohol consumption up to 40% of cases and are more common at this stage that in depressive. This association is greater than that which occurs between alcoholism and schizophrenia or depression. Patients with bipolar disorder who have mixed and irritative states and those with rapid cycling have a prevalence of alcohol consumption and substance use higher than those who do not use substances. It has also been observed that the consumption of alcohol and substance use can change the symptoms of mania and turn them into a mixed state symptoms. It also states that rapid cycles can be precipitated by increased alcohol consumption during rotation from mania to depression.ConclusionsThe association of bipolar disorder with addictive behaviors is a factor that worsens the prognosis and comorbid alcohol itself is associated with a poor prognosis. Close monitoring of bipolar patients and especially in those who consume alcohol is very important.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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Hernández Plaza, L., M. García Navarro, E. Delgado Parada, E. Ochoa Mangado, E. Salvador Vadillo, and S. Molins Pascual. "Agitation in the patient with dual pathology." European Psychiatry 33, S1 (March 2016): S143. http://dx.doi.org/10.1016/j.eurpsy.2016.01.243.

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IntroductionThe consumption of toxic substances often causes agitation, which makes more difficult the pharmacological management of the symptoms.ObjectiveAbout one case, a search was performed of the different therapeutic options in the agitation takes place in the context of intoxication.MethodsThirty-five-year-old male patient diagnosed of dual pathology under treatment since 2003 in our outpatient. The patient shows paranoid schizophrenia disorder due to alcohol, cannabis and cocaine use disorder, summing up different pharmacological treatments with no remission. Whilst the examination is taking place the patient is under alcohol and cannabis effects. His physical and verbal behaviour are aggressive showing psychotic instability. The therapeutic team administers loxapine to its patient.ResultsThe inhaled loxapine turned out to be a good alternative in the case given.ConclusionHandling agitation when toxics are involved is complex. The new formulation of inhaled loxapine helps to control agitation quickly and it might be a feasible option for this kind of patients.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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Esmail, S. "An unusual myopathy with dual pathology: Case report." Journal of the Neurological Sciences 405 (October 2019): 329. http://dx.doi.org/10.1016/j.jns.2019.10.1446.

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Ghosh, SumantaKumar. "Laparoscopic cholecystectomy in double gallbladder with dual pathology." Journal of Minimal Access Surgery 10, no. 2 (2014): 93. http://dx.doi.org/10.4103/0972-9941.129963.

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Kulkarni, Jayashree D., and Sanjay A. Pai. "Dual Pathology: Double Trouble in a Colonic Biopsy." International Journal of Surgical Pathology 25, no. 7 (April 19, 2017): 608. http://dx.doi.org/10.1177/1066896917705199.

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Silber, E., P. Sonnenberg, H. J. Koornhof, L. Morris, and D. Saffer. "Dual infective pathology in patients with cryptococcal meningitis." Neurology 51, no. 4 (October 1, 1998): 1213–15. http://dx.doi.org/10.1212/wnl.51.4.1213.

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Jolobe, O. M. P. "The potential for dual pathology in temporal arteritis." QJM: An International Journal of Medicine 111, no. 1 (November 24, 2017): 67. http://dx.doi.org/10.1093/qjmed/hcx228.

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Osawa, Shin-ichiro, Masaki Iwasaki, Hiroyoshi Suzuki, Nobukazu Nakasato, and Teiji Tominaga. "Occult dual pathology in mesial temporal lobe epilepsy." Neurological Sciences 36, no. 9 (May 30, 2015): 1743–45. http://dx.doi.org/10.1007/s10072-015-2268-0.

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Fernández Mayo, L., E. Barbero García, D. Baño Rodrigo, M. Agujetas Rodríguez, A. García Sanchez, and V. De Antonio Pérez. "Efficacy of vortioxetine for patients with dual pathology." European Psychiatry 41, S1 (April 2017): s861. http://dx.doi.org/10.1016/j.eurpsy.2017.01.1720.

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IntroductionPatients with dual pathology have worse clinical evolution and worse therapeutic response. Drugs modify the functioning of certain neurocerebral transmission systems, producing cognitive, emotional and behavioral changes. Vortioxetine (Brintellix®) is used as a treatment for major depressive disorder (MDD) and it is considered a new multimodal antidepressant. Preclinical data suggest that the effects on numerous serotonin receptors result in regional increases in noradrenaline and dopamine as well as glutamatergic transmission.ObjectivesThis analysis assessed the efficacy of vortioxetine (Brintellix®) in patients with affective disorders and abuse drugs (dual pathology).MethodsEfficacy was assessed with a study of patients who were recruited in a qualitative and observational study. They were treated with vortioxetine (Brintellix®). Outcome measures included changes from baseline to endpoint in Hamilton Depresion Rating Scale (HDRS). They were also interviewed weekly about craving and substance use. Urine test controls were done to corroborate results.ResultsA total of 11 vortioxetine-treated patients improved their depressive and anxiety symptomatology. Seven of them (64%) were males and four of them (36%) were women. Cocaine was the main drug of abuse (n = 9, 82%). The doses were between 5 and 20 mg/day. After the clinical evaluation and 12 weeks of treatment, they achieved to reduce significantly the drug use and verbalized a decrease in craving. Two patients dropped out of the study.ConclusionsVortioxetine (Brintellix®) was shown as efficacious in reducing depressive and anxiety symptoms in patients with dual pathology.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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Che Ab Rahim, Nurul Asma, Jeyasakthy Saniasiaya, and Jeyanthi Kulasegarah. "Dual retrotympanic aural mass." BMJ Case Reports 14, no. 4 (April 2021): e241591. http://dx.doi.org/10.1136/bcr-2021-241591.

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High-riding jugular bulb (HRJB), although rare, may pose a challenge as it may be mistaken for other non-alarming condition, such as middle ear effusion. Patients with HRJB classically present with pulsatile tinnitus. We report a unique case of a 26-year-old patient with underlying beta thalassaemia who presented with a 2-month history of intermittent epistaxis and rhinorrhoea. Otoscopic examinations revealed a pulsatile bluish mass behind the right tympanic membrane and a dull left tympanic membrane. Imaging performed revealed a finding of dual retrotympanic pathology, which consisted of a right dehiscent HRJB and left cholesterol granuloma. We highlight a rare case of dual retrotympanic mass as well as its management.

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Grau, L., C. Daigre, L. Miquel, C. Barral, B. Gonzalvo, G. Fuste, O. Esteve, L. Rodriguez-Cintas, N. Martinez, and C. Roncero. "Medication use in a dual pathology program: Observational study." European Psychiatry 26, S2 (March 2011): 43. http://dx.doi.org/10.1016/s0924-9338(11)71754-0.

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IntroductionPolyfarmacy is frequent in patients with dual diagnosis.AimsTo quantify the number and describe the treatments prescribed in a cohort of outpatients with dual diagnosis.Material and methodsA descriptive and transversal study was performed. Patients with dual diagnosis treated at an Outpatient Drug Treatment Center from January 2005 to December 2009 were included. Data from demographic, clinical and therapeutical variables were gathered once. The instruments used for the diagnosis were EuropASI y SCID-I. The number and type of prescript drugs were related with protocol variables.ResultsThe study sample included 80 patients (71,6% men, average age 37,2 ± 9). Psychotic disorders (46.8%) and cocaine dependence/abuse (34.6%) were the most frequent comorbid psychiatric illnesses found. 40.8% of patients were polydrug users. The mean of prescript drugs was 3,06 ± 1,4 and only 14% of patients were on monotherapy. The frequency of drugs prescribed was: 68,4% antidepressant, 63,3% antipsychotic, 55,7% antiepileptic and 36,7% anxiolytic drugs. Older patients ( > 45years) took a major number of prescripted drugs (3,88 ± 1,1). Patients with psychotic disorders took the 43.9% of drugs prescripted (p = 0,042). Patients with benzodiazepine abuse took higher number of prescription drugs (5 ± 1,4;p = 0,003) compared with patients with other dependence or abuse.ConclusionsPatients with dual diagnosis take high quantity of drugs. Older patients, diagnosis of psychosis and benzodiacepine abuse were related with polydrug prescription. Quantification of medication is recommended for treatment optimisation and avoiding yatrogenic.

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Torales, Julio, João M. Castaldelli-Maia, Antonio Geraldo da Silva, Marcela W. Campos, Israel González-Urbieta, and Iván Barrios. "Even More Complex…. When Mental Disorder Meets Addiction in Youth: Dual Pathology." Current Drug Research Reviews 11, no. 1 (February 26, 2019): 40–43. http://dx.doi.org/10.2174/2589977511666181128165358.

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Background: The management of mental disorders in child and adolescent is challenging. In addition, when substance use disorders are associated with mental disorders, important complications are noted. Dual pathology and Substance-induced disorders should be distinguished in cases like this. Objective: To summarize the latest information on the epidemiology, etiology and management aspects of dual pathology in adolescents. Methods: PubMed, Web of Science, PsycINFO and SciELO databases were searched to perform a narrative review. Results: Dual pathology is the term used to designate the co-occurrence of an addictive disorder and at least one other mental health disorder, independently. To distinguish dual pathology from substance- induced disorders, the temporal association between the disorders in a longitudinal assessment should be emphasized. If the symptoms of the mental disorder appear prior to the substance use or after a long period of abstinence, a diagnosis of dual pathology should be considered. Patients with dual pathology present greater psychosocial issues, more medical problems, and worse prognosis than those with substance-induced disorders. The proposed etiological models agree that biological, psychological and social factors are shared in the development of these conditions. Conclusion: Healthcare systems should focus on creating policies that will allow early detection, preventive public health measures, and an integrated and coordinated care for these patients. Public health policies should create means to promote awareness and prevention of these pathologies since early initiation of treatment (pharmacological, psychotherapeutic, family therapy, education in schools, behavioral interventions and treatment of comorbidities) reduces the risks associated to substance use disorders and other negative consequences.

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Gerami, Mohammad Hassan, Ozra Etemadi, Sayyed Ahmad Ahmadi, and Maryam Fatehizade. "The Pathology of the Dual-Career Couples: A Qualitative Study." Global Journal of Health Science 9, no. 5 (October 19, 2016): 226. http://dx.doi.org/10.5539/gjhs.v9n5p226.

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INTRODUCTION: The structure of traditional family was now changing towards the dual-career ones and due to the impacts that dual-career couples have on the structure of the family, it was necessary to investigate these effects from a discovery perspective. On this base, the present study aims to investigate the pathology of the Iranian dual-career couples’ life.METHOD: In terms of methodology, the study was done qualitatively and it was validated by the grounded theory. The participants were dual-career couples in Yazd. The sampling was done purposefully with 24 participants in a half-organized interview. A theoretically codified method and grounded theory were used to analyze and validate data gathered in this respect.FINDINGS: The findings of the study showed that the pathology of the dual-career couples based on three issues and aspects include entity and conceptual and abstract contents. It included A: reasons and elements (career- family and family-career conflicts, the hierarchical order for power and influence, issues and management of financial and economic affairs), B: actions (the responsibility division, the problem of sexual and marital relations in, the issues of child raising and child rearing, decrease of intimacy and the time of being together), and C: consequences (lack of happiness and joy, decrease of the relations with the relatives, nutritional, spiritual and psychological issues).CONCLUSION: Generally, the results of the study showed that dual-career couples’ experience the pathology and conflicts influence their job and these pathologies were presented in the form of a conceptual model.

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Hilal, Kiran, Anam Khan, Nida Sajjad, and Kumail Khandwala. "Cystic Nephroma with Pleuropulmonary Blastoma: A Rare Dual Pathology." APSP Journal of Case Reports 9, no. 1 (March 21, 2018): 3. http://dx.doi.org/10.21699/ajcr.v9i1.657.

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Cystic nephroma (CN) belongs to a heterogeneous group of renal cystic tumors while pleuropulmonary blastoma is an uncommon pediatric lung neoplasm, believed to be originating either from lung tissue itself or from the pleura. Synchronous development of pleuropulmonary blastoma following cystic nephroma is a rare entity in pediatric patients. The etiology and pathogenesis of this dual pathology is still unknown. We report a case of a child who presented with an abdominal mass diagnosed as cystic nephroma on surgical resection, who later developed a thoracic lesion which was subsequently diagnosed as pleuropulmonary blastoma.

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Li, L. M. "Surgical outcome in patients with epilepsy and dual pathology." Brain 122, no. 5 (May 1, 1999): 799–805. http://dx.doi.org/10.1093/brain/122.5.799.

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Cupples, H. E. V., and D. T. McGahey. "Dual pathology: cervicofacial actinomycosis and nicorandil-induced oral ulceration." Journal of Laryngology & Otology 122, no. 4 (May 14, 2007): 422–24. http://dx.doi.org/10.1017/s002221510700816x.

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AbstractIntroduction:Oral ulceration has many causes and is a common presenting symptom in otolaryngology.Case report:This article presents an unusual case of dual pathology oral ulceration in an elderly patient. Oral malignancy was initially suspected, but the history, examination and investigation showed that the oral ulceration was caused by actinomycosis infection and by nicorandil use.Discussion:Cervicofacial acinomycosis is a rare, suppurative bacterial disease in which abscesses can form in the tissues and break through the skin, creating pus-discharging lesions. Nicorandil is a potassium channel blocker used in the treatment of ischaemic heart disease. It has been recently recognised as a cause of persistent ulcerative stomatitis.Conclusion:This case highlights the importance of a high index of suspicion for unusual and reversible causes of oral ulceration, and of dual pathology as a cause. Such vigilance enables early recognition and treatment of potentially reversible conditions.

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Wei, Linpeng, Chengbo Yin, and Jonathan T. C. Liu. "Dual-Axis Confocal Microscopy for Point-of-Care Pathology." IEEE Journal of Selected Topics in Quantum Electronics 25, no. 1 (January 2019): 1–10. http://dx.doi.org/10.1109/jstqe.2018.2854572.

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van Elst, L. T. "Dual Brain Pathology in Patients With Affective Aggressive Episodes." Archives of General Psychiatry 58, no. 12 (December 1, 2001): 1187. http://dx.doi.org/10.1001/archpsyc.58.12.1187.

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Salanova, V., O. Markand, and R. Worth. "Temporal lobe epilepsy: analysis of patients with dual pathology." Acta Neurologica Scandinavica 109, no. 2 (October 1, 2003): 126–31. http://dx.doi.org/10.1034/j.1600-0404.2003.00183.x.

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Juhász, Csaba, Ferenc Nagy, Otto Muzik, Craig Watson, Jagdish Shah, and Harry T. Chugani. "[11ClFlumazenil PET in Patients with Epilepsy with Dual Pathology." Epilepsia 40, no. 5 (May 1999): 566–74. http://dx.doi.org/10.1111/j.1528-1157.1999.tb05558.x.

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Rathore, Chaturbhuj, Bejoy Thomas, Chandrasekharan Kesavadas, and Kurupath Radhakrishnan. "Calcified neurocysticercosis lesions and hippocampal sclerosis: Potential dual pathology?" Epilepsia 53, no. 4 (January 13, 2012): e60-e62. http://dx.doi.org/10.1111/j.1528-1167.2011.03386.x.

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Jolobe, O. M. P. "Dual pathology may be masked by iron replacement therapy." QJM: An International Journal of Medicine 111, no. 2 (December 12, 2017): 139. http://dx.doi.org/10.1093/qjmed/hcx246.

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Marzo, Vincenzo Di, John R. Tippins, and Howard R. Morris. "Dual role of neuropeptidergic system in pathology of asthma?" Trends in Pharmacological Sciences 8, no. 5 (May 1987): 168–69. http://dx.doi.org/10.1016/0165-6147(87)90158-1.

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Thambidorai, C. R., I. Muin, J. Razman, and A. Zulfiqar. "Currarino Triad With Dual Pathology in the Presacral Mass." Diseases of the Colon & Rectum 46, no. 7 (July 2003): 974–77. http://dx.doi.org/10.1007/s10350-004-6696-9.

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Marin, S. Garcia, I. De Haro Garcia, N. Martinez Pedrosa, M. D. Ortega García, V. Marti Garnica, S. Galiano Rus, A. Soler Iborte, and P. Lucas Borja. "New horizons of dual pathology, report of a case." European Psychiatry 41, S1 (April 2017): S472. http://dx.doi.org/10.1016/j.eurpsy.2017.01.543.

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IntroductionPathological gambling, as behavioural addiction, is always related with psychosocial important problems. In this case, everything is even more difficult due to grave mental disease associated, Paranoid Schizophrenia. Man, 26 years old, single. He was diagnosed of psychotic disease at the beginning due to his grave addiction to THC and others stimulant drugs. His outpatient treatment was complicated and he needed to be hospitalised once (being diagnosed of Schizophrenia). After that, he improved till he got a standardised job. He was able to have his medical treatment (Aripriprazol 15 mgs per day and Biperidene 4 mgs per day) although he kept his isolation. Then, the patient could talk about his pathological gambling. He suffered from slot machine addiction, and he also suffered from depression symptoms closely related to family and economic problems due to pathological gambling. This patient was in contemplation state and he accepted to start with antidepressant (Mirtazapine 15 mgs per day) and psychological treatment. We agreed to make a record of his gambling uses (with regular self-reports). His salary would be administered by his parents and he only could take a little money every week. The treatment was useful; it increased the capacity of economic self-management and the recovery of depression disease related.ConclusionsIn our opinion, he used gambling as filling a need for activity, and as a way of connecting with society/world. These findings suggest the need for improved prevention and treatment efforts related to problem/pathological gambling in individuals with psychotic disorders.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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Murphy, Siun M., Katherine Browne, David J. Tuite, and Michael O'Shaughnessy. "Dual pathology proximal median nerve compression of the forearm." Journal of Plastic, Reconstructive & Aesthetic Surgery 66, no. 12 (December 2013): 1792–94. http://dx.doi.org/10.1016/j.bjps.2013.04.054.

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Mahan, Mark A., Kimberly K. Amrami, and Robert J. Spinner. "Dual pathology affecting the proximal median nerve is interrelated." Journal of Plastic, Reconstructive & Aesthetic Surgery 67, no. 3 (March 2014): 428–30. http://dx.doi.org/10.1016/j.bjps.2013.09.022.

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Caprihan, Arvind, Rajikha Raja, Laura J. Hillmer, Erik Barry Erhardt, Jill Prestopnik, Jeffrey Thompson, John C. Adair, Janice E. Knoefel, and Gary A. Rosenberg. "A double-dichotomy clustering of dual pathology dementia patients." Cerebral Circulation - Cognition and Behavior 2 (2021): 100011. http://dx.doi.org/10.1016/j.cccb.2021.100011.

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Lévesque, Michel F., Nobukazu Nakasato, Harry V. Vinters, and Thomas L. Babb. "Surgical treatment of limbic epilepsy associated with extrahippocampal lesions: the problem of dual pathology." Journal of Neurosurgery 75, no. 3 (September 1991): 364–70. http://dx.doi.org/10.3171/jns.1991.75.3.0364.

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✓ The authors present their review of 178 patients who underwent en bloc temporal lobectomies as surgical treatment for intractable epilepsy. Hippocampal cell density was quantitatively analyzed and the histology of the anterior temporal lobe was reviewed. Fifty-four patients (30.3%) had evidence of extrahippocampal lesions in addition to neuronal cell loss within the hippocampus (the dual pathology group). The pattern of cell loss was analyzed in the remaining 124 cases (69.7%) with no extrahippocampal pathology, and compared with that of the dual pathology group and a control group of four nonepileptic patients. Hippocampal cell loss was found in almost all epileptic patients compared to the control group. Severe cell loss greater than 30% of control values was found in 88.7% of patients without extrahippocampal lesions, but in only 51.8% of patients with dual pathology. The difference between these two groups was statistically significant (p < 0.001). In the dual pathology group, lesions of different pathology had a significant relationship with the degree of hippocampal cell loss: all 12 patients with glioma had mild cell loss, whereas all 13 patients with heterotopia were associated with severe cell loss. Severity of hippocampal cell loss was also analyzed in relation to seizure history: a prior severe head injury was associated with severe cell loss. Other factors such as seizure duration, secondary generalization, or family history of seizures were not associated with hippocampal damage. Dual pathology may produce a combination of neocortical and temporolimbic epilepsies that warrants a precise definition of the true epileptogenic area prior to surgical treatment.

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Gomez Revuelta, M., M. Juncal Ruiz, O. Porta Olivares, L. Sanchez Blanco, D. Abejas Diez, G. Pardo de Santayana Jenaro, R. Landera Rodriguez, N. I. Nuñez Morales, and L. Garcia Ayala. "Dual Diagnosis and Medical Co-morbidity: Data from a Specialized Brief Psychiatric In-patient Unit." European Psychiatry 41, S1 (April 2017): S137. http://dx.doi.org/10.1016/j.eurpsy.2017.01.1963.

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IntroductionPrevious research on the prevalence of medical disorders among adults with dual diagnosis (DD) has been inconclusive.ObjectivesThe purpose of this study was to assess dual diagnosis and medical co-morbidity at the Brief Psychiatric Inpatient Unit of Marqués de Valdecilla Hospital, Santander in the period from January 2014 until March 2015.MethodsNinety-three patients were admitted at our hospital from December 2014 until March 2015. The simple was analyzed retrospectively. Sixty-two of the patients (66.7%) met criteria for Dual Diagnosis. We collected socio-demographic variables, drug abuse, mental pathology, and treatment received.ResultsThe mean age of the sample was 42.95 years (± 14 DS) with a male:female ratio of 1.8:1 (no significant differences by gender). Hypertension was more prevalent among patients without dual pathology (22.5%). Patients with dual diagnosis presented hypertension less likely (6.5%) (P < 0.005). This can be explained by the fact that patients without dual diagnosis had a higher mean age (47 years) than patients with dual diagnosis (42 years). We did not found statistically significant differences between both groups respect to diabetes mellitus, vascular brain disease, HIV and dyslipidemia.ConclusionsHypertension was less likely to appear among patients with dual pathology admitted to an ultra brief psychiatry unit. This could be explained for an earlier mean age at admission among these patients.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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Monfort Montolio, Miguel, and Javier Sancho-Pelluz. "Animal-Assisted Therapy in the Residential Treatment of Dual Pathology." International Journal of Environmental Research and Public Health 17, no. 1 (December 23, 2019): 120. http://dx.doi.org/10.3390/ijerph17010120.

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Animal-assisted therapy (AAT) is a complementary intervention of therapy that has shown positive results in the treatment of various pathologies. This study assesses the viability of the implementation and the effectiveness of an AAT program in patients diagnosed with substance abuse disorder and associated mental disorders (dual pathology). For the study, a dynamic prospective cohort was used, consisting of 43 patients in residential treatment. The program consisted of 10 sessions with a duration of about 60 min, where data was collected in the 3rd, 6th and 10th sessions. The Life Skills Profile questionnaire (LSP) and the Barratt Impulsiveness Scale (BIS-11) were used for subsequent evaluation. Patients who participated in the program showed an improvement in daily skills, which favoured a better quality of life and decreased impulsiveness, enabling them to regain self-control. These results suggest that the dog can be a multi-sensory stimulus that captures attention, and improves motivation, cooperation and patient involvement in therapy. It was concluded that AAT can serve as an adjunctive therapy in the rehabilitation processes of people diagnosed with dual pathology.

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Johnsen, Erik, and Bradley Deere. "DUAL SPONTANEOUS PAPILLARY MUSCLE RUPTURE - UNIQUE PRESENTATION OF UNUSUAL PATHOLOGY." Journal of the American College of Cardiology 75, no. 11 (March 2020): 2315. http://dx.doi.org/10.1016/s0735-1097(20)32942-9.

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Rashid, M., D. Y. H. Lee, and C. H. K. Tang. "11: A case study of dual pathology of lung cancer." Lung Cancer 103 (January 2017): S6. http://dx.doi.org/10.1016/s0169-5002(17)30061-2.

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Vargas Castro, J. A., A. Rodríguez, T. Grau, G. Faus, and M. Sánchez Povedano. "EPA-1413 – New technology in child and adolescents dual pathology." European Psychiatry 29 (2014): 1. http://dx.doi.org/10.1016/s0924-9338(14)78617-1.

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Fernández Mayo, L., D. Baño Rodrigo, and E. Barbero García. "Dual Pathology: Craving and Drug Abuse in Patients On Paliperidone." European Psychiatry 30 (March 2015): 1064. http://dx.doi.org/10.1016/s0924-9338(15)30839-7.

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Journal articles on the topic 'Dual pathology'

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