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Journal articles on the topic 'Dye-loaded polymeric nanoparticles'

Author: Grafiati

Published: 25 May 2024

Last updated: 31 July 2025

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1

Tumpa, Naz Fathma, Mingyeong Kang, Jiae Yoo, Sunju Kim, and Minseok Kwak. "Rylene Dye-Loaded Polymeric Nanoparticles for Photothermal Eradication of Harmful Dinoflagellates, Akashiwo sanguinea and Alexandrium pacificum." Bioengineering 9, no. 4 (2022): 170. http://dx.doi.org/10.3390/bioengineering9040170.

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In the era of climate changes, harmful dinoflagellate outbreaks that produce potent algal toxins, odor, and water discoloration in aquatic environments have been increasingly reported. Thus, various treatments have been attempted for the mitigation and management of harmful blooms. Here, we report engineered nanoparticles that consist of two different types of rylene derivatives encapsulated in polymeric micelles. In addition, to avoid dissociation of the aggregate, the core of micelle was stabilized via semi-interpenetrating network (sIPN) formation. On two types of the marine red-tide dinofl

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Zerrillo, Luana, Karthick Babu Sai Sankar Gupta, Fons A. W. M. Lefeber, et al. "Novel Fluorinated Poly (Lactic-Co-Glycolic acid) (PLGA) and Polyethylene Glycol (PEG) Nanoparticles for Monitoring and Imaging in Osteoarthritis." Pharmaceutics 13, no. 2 (2021): 235. http://dx.doi.org/10.3390/pharmaceutics13020235.

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Polymeric nanoparticles (NPs) find many uses in nanomedicine, from drug delivery to imaging. In this regard, poly (lactic-co-glycolic acid) (PLGA) and polyethylene glycol (PEG) particles are the most widely applied types of nano-systems due to their biocompatibility and biodegradability. Here we developed novel fluorinated polymeric NPs as vectors for multi-modal nanoprobes. This approach involved modifying polymeric NPs with trifluoroacetamide (TFA) and loading them with a near-infrared (NIR) dye for different imaging modalities, such as magnetic resonance imaging (MRI) and optical imaging. T

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Melnychuk, Nina, Pichandi Ashokkumar, Ilya O. Aparin, and Andrey S. Klymchenko. "Pre- and Postfunctionalization of Dye-Loaded Polymeric Nanoparticles for Preparation of FRET-Based Nanoprobes." ACS Applied Polymer Materials 4, no. 1 (2021): 44–53. http://dx.doi.org/10.1021/acsapm.1c00819.

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Adarsh, Nagappanpillai, and Andrey S. Klymchenko. "Ionic aggregation-induced emission dye with bulky counterions for preparation of bright near-infrared polymeric nanoparticles." Nanoscale 11 (July 1, 2019): 13977–87. https://doi.org/10.1039/C9NR04085D.

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Dyes exhibiting aggregation-induced emission (AIE) are attractive building blocks for the preparation of bright fluorescent nanomaterials. AIEgens are especially efficient in pure dye aggregates, whereas they are much less explored as dopants in NPs built of hydrophobic polymers. Here, we describe an approach that combines cationic AIEgens with bulky hydrophobic counterions (fluorinated tetraphenylborates) that enables preparation of small and bright AIEgen-loaded polymeric NPs. To this end, we synthesised a cationic tetraphenylethylene (TPE) derivative and studied its salts with counterions o

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Guastaferro, Mariangela, Lucia Baldino, Vincenzo Vaiano, Stefano Cardea, and Ernesto Reverchon. "Supercritical Phase Inversion to Produce Photocatalytic Active PVDF-coHFP_TiO2 Composites for the Degradation of Sudan Blue II Dye." Materials 15, no. 24 (2022): 8894. http://dx.doi.org/10.3390/ma15248894.

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TiO2-loaded poly(vinylidene fluoride-co-hexafluoropropylene) (PVDF-coHFP) membranes were produced by supercritical CO2-assisted phase inversion. Three different TiO2 loadings were tested: 10, 20, and 30 wt% with respect to the polymer. Increasing the TiO2 amount from 10 wt% to 20 wt% in the starting solution, the transition from leafy-like to leafy-cellular morphology was observed in the section of the membrane. When 30 wt% TiO2 was used, the entire membrane section showed agglomerates of TiO2 nanoparticles. These polymeric membranes were tested to remove Sudan Blue II (SB) dye from aqueous so

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Egloff, Sylvie, Nina Melnychuk, Elisabete Cruz Da Silva, Andreas Reisch, Sophie Martin, and Andrey S. Klymchenko. "Amplified Fluorescence in Situ Hybridization by Small and Bright Dye-Loaded Polymeric Nanoparticles." ACS Nano 16, no. 1 (2021): 1381–94. http://dx.doi.org/10.1021/acsnano.1c09409.

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Melnychuk, Nina, and Andrey S. Klymchenko. "DNA-Functionalized Dye-Loaded Polymeric Nanoparticles: Ultrabright FRET Platform for Amplified Detection of Nucleic Acids." Journal of the American Chemical Society 140, no. 34 (2018): 10856–65. http://dx.doi.org/10.1021/jacs.8b05840.

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Obinu, Antonella, Elisabetta Gavini, Giovanna Rassu, et al. "Indocyanine Green Loaded Polymeric Nanoparticles: Physicochemical Characterization and Interaction Studies with Caco-2 Cell Line by Light and Transmission Electron Microscopy." Nanomaterials 10, no. 1 (2020): 133. http://dx.doi.org/10.3390/nano10010133.

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Biomedical applications of nanoparticles (NPs) have reached an increasing development in recent years. Recently, we demonstrated that newly synthesized poly (ethyl 2-cyanoacrylate) nanoparticles (PECA-NPs) are possible antitumor agents due to their cytotoxicity for cancer cells. Indocyanine green (ICG), an amphiphilic tricarbocyanine fluorescent dye, is widely used for the detection of tumoral extension in different organs during clinical surgery. Moreover, this fluorescent agent is unstable and it has a rapid clearance in physiological conditions in vivo. In this study, ICG was charged in PEC

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Andreiuk, Bohdan, Andreas Reisch, Eduard Bernhardt, and Andrey S. Klymchenko. "Fighting aggregation-caused quenching and leakage of dyes in fluorescent polymer nanoparticles: universal role of counterion." Chem. Asian J. 14, no. 6 (2019): 836–46. https://doi.org/10.1002/asia.201801592.

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Dye‐loaded polymer nanoparticles (NPs) emerge as a powerful tool for bioimaging applications, owing to their exceptional brightness and controlled small size. However, aggregation‐caused quenching (ACQ) and leakage of dyes at high loading remain important challenges of these nanomaterials. The use of bulky hydrophobic counterions has been recently proposed as an effective approach to minimize ACQ and dye leakage, but the role of counterion structure is still poorly understood. Here, a systematic study based on ten counterions, ranging from small hydrophilic perchlorate up to large hydrophobic

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Lei, Tingjun, Alicia Fernandez-Fernandez, Romila Manchanda, Yen-Chih Huang, and Anthony J. McGoron. "Near-infrared dye loaded polymeric nanoparticles for cancer imaging and therapy and cellular response after laser-induced heating." Beilstein Journal of Nanotechnology 5 (March 18, 2014): 313–22. http://dx.doi.org/10.3762/bjnano.5.35.

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Background: In the past decade, researchers have focused on developing new biomaterials for cancer therapy that combine imaging and therapeutic agents. In our study, we use a new biocompatible and biodegradable polymer, termed poly(glycerol malate co-dodecanedioate) (PGMD), for the synthesis of nanoparticles (NPs) and loading of near-infrared (NIR) dyes. IR820 was chosen for the purpose of imaging and hyperthermia (HT). HT is currently used in clinical trials for cancer therapy in combination with radiotherapy and chemotherapy. One of the potential problems of HT is that it can up-regulate hyp

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Kumar, Piyush, Tim Van Treuren, Amalendu P. Ranjan, Pankaj Chaudhary, and Jamboor K. Vishwanatha. "In vivo imaging and biodistribution of near infrared dye loaded brain-metastatic-breast-cancer-cell-membrane coated polymeric nanoparticles." Nanotechnology 30, no. 26 (2019): 265101. http://dx.doi.org/10.1088/1361-6528/ab0f46.

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Gupta, Priya. "Abstract A031: Development of poly lactic acid based biodegradable nanoparticles for co-delivery of pirarubicin and gemcitabine for synergistic anti-tumor efficacy." Molecular Cancer Therapeutics 22, no. 12_Supplement (2023): A031. http://dx.doi.org/10.1158/1535-7163.targ-23-a031.

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Abstract Nanoparticles based drug delivery systems have provided a befitted solution for the poor pharmacokinetic properties and systemic toxicity caused by the chemo drugs because of their ability to improve bioavailability of the drugs at the desired site and thereby decreasing extracellular toxicity. The present work investigates the single or dual chemo drugs loaded PLA-based biodegradable polymeric nanoparticles for improved anti-tumor efficacy as compared to free drug formulations. For the study, an amphiphilic block copolymer; mPEG PLA has been synthesized and characterized using Gel pe

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Amin, Keristina Wagdi K., Ágota Deák, Miklós Csanády, et al. "pH-Triggered Hydrogel Nanoparticles for Efficient Anticancer Drug Delivery and Bioimaging Applications." Pharmaceutics 16, no. 7 (2024): 931. http://dx.doi.org/10.3390/pharmaceutics16070931.

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In this work, we developed multifunctional hydrogel nanoparticles (NPs) that can encapsulate anticancer drugs and imaging contrast agents as well. Mitomycin C (MMC) and rhodamine B (RB) were selected as models for anticancer drugs and imaging contrasting agents, respectively. Both MMC and RB were linked to the succinated polyvinyl alcohol polymer (PVA-SA). The selected labeled hydrogel NPs ((0.5% RB)-PVA-SA NPs and (1.5% RB)-PVA-SA NPs) improved the RB quantum yield from 29.8% to a minimum of 42.7%. Moreover, they showed higher emission stability compared to free RB when they were repeatedly e

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Md, Shadab, Nabil A. Alhakamy, Thikryat Neamatallah та ін. "Development, Characterization, and Evaluation of α-Mangostin-Loaded Polymeric Nanoparticle Gel for Topical Therapy in Skin Cancer". Gels 7, № 4 (2021): 230. http://dx.doi.org/10.3390/gels7040230.

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The aim of this study was to prepare and evaluate α-mangostin-loaded polymeric nanoparticle gel (α-MNG-PLGA) formulation to enhance α-mangostin delivery in an epidermal carcinoma. The poly (D, L-lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) were developed using the emulsion–diffusion–evaporation technique with a 3-level 3-factor Box–Behnken design. The NPs were characterized and evaluated for particle size distribution, zeta potential (mV), drug release, and skin permeation. The formulated PLGA NPs were converted into a preformed carbopol gel base and were further evaluated for texture a

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Zhao, Tingbi, Tsukuru Masuda, Eiji Miyoshi, and Madoka Takai. "High Dye-Loaded and Thin-Shell Fluorescent Polymeric Nanoparticles for Enhanced FRET Imaging of Protein-Specific Sialylation on the Cell Surface." Analytical Chemistry 92, no. 19 (2020): 13271–80. http://dx.doi.org/10.1021/acs.analchem.0c02502.

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Ambreen, Jaweria, Abdul Haleem, Aqeel Ahmed Shah, et al. "Facile Synthesis and Fabrication of NIPAM-Based Cryogels for Environmental Remediation." Gels 9, no. 1 (2023): 64. http://dx.doi.org/10.3390/gels9010064.

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Herein, polymeric cryogels containing poly(N-isopropylacrylamide) were synthesized by cryo-polymerization at subzero temperature. The synthesized cryogels were loaded with silver and palladium nanoparticles by the chemical reduction method at room temperature using the reducing agent NaBH4. Moreover, for comparison with cryogels, pure poly(N-isopropylacrylamide) hydrogel and its silver hybrid were also prepared by the conventional method at room temperature. The chemical structure and functional group analysis of the pure cryogels was confirmed by Fourier transform infrared spectroscopy. The s

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Nabil, Ghazal, Rami Alzhrani, Hashem Alsaab, et al. "CD44 Targeted Nanomaterials for Treatment of Triple-Negative Breast Cancer." Cancers 13, no. 4 (2021): 898. http://dx.doi.org/10.3390/cancers13040898.

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Identified as the second leading cause of cancer-related deaths among American women after lung cancer, breast cancer of all types has been the focus of numerous research studies. Even though triple-negative breast cancer (TNBC) represents 15–20% of the number of breast cancer cases worldwide, its existing therapeutic options are fairly limited. Due to the pivotal role of the presence/absence of specific receptors to luminal A, luminal B, HER-2+, and TNBC in the molecular classification of breast cancer, the lack of these receptors has accounted for the aforementioned limitation. Thereupon, in

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Adarsh, Nagappanpillai, and Andrey S. Klymchenko. "Ionic aggregation-induced emission dye with bulky counterions for preparation of bright near-infrared polymeric nanoparticles." Nanoscale 11, no. 29 (2019): 13977–87. http://dx.doi.org/10.1039/c9nr04085d.

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Szwajca, Anna, Sandra Juszczyńska, Maciej Jarzębski, and Elżbieta Baryła-Pankiewicz. "Incorporation of Fluorescent Fluorinated Methacrylate Nano-Sized Particles into Chitosan Matrix Formed as a Membranes or Beads." Polymers 14, no. 13 (2022): 2750. http://dx.doi.org/10.3390/polym14132750.

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Fluorescent particles are of particular interest as probes and active agents for biomedical, pharmaceutical, and food applications. Here, we present two strategies for incorporation of core-shell acrylic fluorescent nanoparticles (NPs) with Rhodamine B (RhB) as a dye into a chitosan (CS) matrix. We selected two variants of NPsRhB immobilisation in a CS membrane and biopolymeric CS beads. Modification of the method for production of the biopolymer cover/transporter of nanoparticles allowed two series of hydrogels loaded with nanoparticles to be obtained with a similar concentration of the aqueo

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Rybak, Ewa, Piotr Kowalczyk, Sylwia Czarnocka-Śniadała, Michał Wojasiński, Jakub Trzciński та Tomasz Ciach. "Microfluidic-Assisted Formulation of ε-Polycaprolactone Nanoparticles and Evaluation of Their Properties and In Vitro Cell Uptake". Polymers 15, № 22 (2023): 4375. http://dx.doi.org/10.3390/polym15224375.

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The nanoprecipitation method was used to formulate ε-polycaprolactone (PCL) into fluorescent nanoparticles. Two methods of mixing the phases were evaluated: introducing the organic phase into the aqueous phase dropwise and via a specially designed microfluidic device. As a result of the nanoprecipitation process, fluorescein-loaded nanoparticles (NPs) with a mean diameter of 127 ± 3 nm and polydispersity index (PDI) of 0.180 ± 0.009 were obtained. The profiles of dye release were determined in vitro using dialysis membrane tubing, and the results showed a controlled release of the dye from NPs

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Aljeddani, Ghalia Saleem, Reem Mohammad Alghanmi, and Ragaa A. Hamouda. "Study on the Isotherms, Kinetics, and Thermodynamics of Adsorption of Crystal Violet Dye Using Ag-NPs-Loaded Cellulose Derived from Peanut-Husk Agro-Waste." Polymers 15, no. 22 (2023): 4394. http://dx.doi.org/10.3390/polym15224394.

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A huge amount of textile dyes are released as industrial waste into the environment each year, which alters the water’s natural appearance and causes toxicity and carcinogenicity in the human body. Peanut husk is considered an agro-waste and contains many valuable compounds, such as cellulose. Different concentrations of cellulose were extracted from peanut husk and then loaded with bio-silver nanoparticles, which were fabricated using neem leaves (Azadirachta indica) as a reducing agent to form Ag-cellulose nanocomposites (Ag-Cell-NCMs). Different devices were used to characterize Ag-Cell-NCM

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Alqarni, Sara A. "The Performance of Different AgTiO2 Loading into Poly(3-Nitrothiophene) for Efficient Adsorption of Hazardous Brilliant Green and Crystal Violet Dyes." International Journal of Polymer Science 2022 (January 5, 2022): 1–17. http://dx.doi.org/10.1155/2022/4691347.

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The in-situ polymerization technology was used to successfully produce nanostructured binary nanocomposites (NCs) made from a poly (3-nitrothiophen) matrix (P3NT) that were loaded effectively with nanoparticles (NPs) of silver titanium dioxide (AgTiO2), of varying percentages (10%, 20%, and 30%). A uniform coating of P3NT covers the AgTiO2 NPs. Various methods were performed to confirm the fabrication of the binary P3NT/AgTiO2 NCs adsorbents, such as FTIR, XRD, SEM, and EDX. Both dyes (brilliant green (B.G.) and crystal violet (C.V.)) were removed from liquid media by using the binary P3NT/AgT

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Benali, Fadila, Bouhadjar Boukoussa, Nour-El-Houda Benkhedouda, et al. "Catalytic Reduction of Dyes and Antibacterial Activity of AgNPs@Zn@Alginate Composite Aerogel Beads." Polymers 14, no. 22 (2022): 4829. http://dx.doi.org/10.3390/polym14224829.

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This work focuses on the preparation of aerogel composite beads based on Zn(II)-crosslinked alginate and loaded with different percentages of AgNPs using a simple approach. The obtained samples were evaluated in two different applications: the first application consists in their use as catalysts for the reduction of MB, MO, OG and CR dyes in a simple and binary system under the presence of NaBH4. For this, several parameters affecting the catalytic behavior of these catalysts have been investigated and discussed such as the catalyst mass, AgNPs content, dye nature, and the selectivity of the c

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Farheen, Jabeen, and Simeen Mansoor. "Anti-stress phytohormones impact on proteome profile of green gram (Vigna radiata) under salt toxicity." World Journal of Biology and Biotechnology 5, no. 2 (2020): 17. http://dx.doi.org/10.33865/wjb.005.02.0213.

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Green gram (Vigna radiata) is considered the chief legume in Pakistan. Thus, current study was conducted to examine the ameliorating effect of phytohormones pre-treatments under salt stress on proteome profile of green gram by sodium-dodecyl-sulphate-polyacrylamide gel electrophoresis (SDS-PAGE). The soluble green gram seedlings proteins were resolved on 4% stacking and 12% resolving gels. The SDS-PAGE resolved 24 polypeptide bands ranging from 200 to 17kDa. Among these, 12 out of 24 bands of proteins were essentials house-keeping or growth proteins of green grams. While, 120, 114.6, 51.8, 29.

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Sergeev, Igor S., Elizaveta A. Maksimova, Ekaterina O. Moiseeva, et al. "Photoinduced Toxicity Caused by Gold Nanozymes and Photodynamic Dye Encapsulated in Submicron Polymer Shell." Particle & Particle Systems Characterization, January 27, 2024. http://dx.doi.org/10.1002/ppsc.202300149.

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AbstractThe development of nanozymes, artificial enzymes made from inorganic nanoparticles, is widely studied due to their affordability, durability, and strength. Gold nanoparticles (AuNPs) are employed to imitate peroxidase, glucose oxidase, lactate oxidase, superoxide dismutase, and catalase. The last one transforms intracellular hydrogen peroxide into molecular oxygen, whose deficiency is characteristic of the hypoxic tumor microenvironment. Thus, gold nanoparticles are thought to enhance the overall effectiveness of photodynamic therapy. However, the enzyme‐like activity of nanoparticles

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Biswas, Deep Sekhar, Nina Melnychuk, Caterina Severi, Pascal Didier, and Andrey S. Klymchenko. "Giant Light‐Harvesting in Dye‐Loaded Nanoparticles Enhanced by Blank Hydrophobic Salts." Advanced Optical Materials, October 18, 2023. http://dx.doi.org/10.1002/adom.202301671.

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AbstractLight‐harvesting is a fundamental process in nature, which inspires researchers to develop artificial systems for photocatalysis, photovoltaics, and biosensing. A previously introduced light‐harvesting nanoantenna, based on polymeric nanoparticles (NPs) loaded with rhodamine dyes and bulky hydrophobic counterions, provides a record‐breaking antenna effect ≈1000. However, the high dye cooperativity of its thousands of encapsulated dyes causes energy losses by traces of self‐quenched dye aggregates. Here, it is found that these imperfections can be suppressed by blank hydrophobic salts (

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Hamon, Casey L., Christopher L. Dorsey, Tuğba Özel, Eugenia M. Barnes, Todd W. Hudnall, and Tania Betancourt. "Near-infrared fluorescent aza-BODIPY dye-loaded biodegradable polymeric nanoparticles for optical cancer imaging." Journal of Nanoparticle Research 18, no. 7 (2016). http://dx.doi.org/10.1007/s11051-016-3518-7.

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Wong, Calvin, and Emmanuel A. Ho. "Development of modular polymeric nanoparticles for drug delivery using amine reactive chemistry." Journal of Pharmacy & Pharmaceutical Sciences 27 (August 6, 2024). http://dx.doi.org/10.3389/jpps.2024.13148.

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Curcumin has been explored for its anti-cancer potential, but is severely limited by its hydrophobicity and sensitivity to light and water. In this study, poly (lactic-co-glycolic) acid (PLGA) nanoparticles (NPs) were synthesized to encapsulate curcumin via single emulsion method to improve curcumin stability and bioavailability. The PLGA NPs were coated with oligomeric chitosan (COS) and RGD peptide (a peptide consisting of Arg-Gly-Asp) using amine-reactive chemistry (NHS and EDC). Both COS and RGD had been previously shown to accumulate and target many different types of cancer cells. NPs we

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Sala, Matteo, Matteo Orfano, Valeria Secchi та ін. "Highly Luminous Scintillating Nanocomposites Enable Ultrafast Time Coincidence Resolution for γ‐rays Detection with Heterostructured Multilayer Scintillators". Advanced Functional Materials, 19 грудня 2024. https://doi.org/10.1002/adfm.202421434.

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AbstractBrighter fast scintillators are needed for advanced applications to acquire data with high signal‐to‐noise ratio in short time windows, like in the time‐of‐flight positron emission tomography (ToF‐PET) imaging technique for cancer. A new composite polymeric fast scintillator loaded with high‐density hafnium dioxide (HfO2, hafnia) nanoparticles is developed here to be used for detection of the 511 keV γ‐rays employed in ToF‐PET. By a fine tuning and engineering of the electronic properties of its components, namely the polymeric matrix, the dense nanoparticles and the embedded fluoresce

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Kromer, Charlotte, Karin Schwibbert, Ashish K. Gadicherla, et al. "Monitoring and imaging pH in biofilms utilizing a fluorescent polymeric nanosensor." Scientific Reports 12, no. 1 (2022). http://dx.doi.org/10.1038/s41598-022-13518-1.

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AbstractBiofilms are ubiquitous in nature and in the man-made environment. Given their harmful effects on human health, an in-depth understanding of biofilms and the monitoring of their formation and growth are important. Particularly relevant for many metabolic processes and survival strategies of biofilms is their extracellular pH. However, most conventional techniques are not suited for minimally invasive pH measurements of living biofilms. Here, a fluorescent nanosensor is presented for ratiometric measurements of pH in biofilms in the range of pH 4.5–9.5 using confocal laser scanning micr

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Cruz Da Silva, Elisabete, Paraskevi Gaki, Fabien Flieg, et al. "Direct Zeptomole Detection of RNA Biomarkers by Ultrabright Fluorescent Nanoparticles on Magnetic Beads." Small, July 16, 2024. http://dx.doi.org/10.1002/smll.202404167.

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AbstractNucleic acids are important biomarkers in cancer and viral diseases. However, their ultralow concentration in biological/clinical samples makes direct target detection challenging, because it leads to slow hybridization kinetics with the probe and its insufficient signal‐to‐noise ratio. Therefore, RNA target detection is done by molecular (target) amplification, notably by RT‐PCR, which is a tedious multistep method that includes nucleic acid extraction and reverse transcription. Here, a direct method based on ultrabright dye‐loaded polymeric nanoparticles in a sandwich‐like hybridizat

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Eaton, David A., Anna Y. Lynn, Juliana M. Surprenant, et al. "Biodistribution of Polymeric Nanoparticles following In-Utero Delivery to a Non-Human Primate." Biomedicine Hub, December 12, 2024, 1–16. https://doi.org/10.1159/000543138.

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Monogenic diseases can be diagnosed before birth. Systemic fetal administration of nanoparticles (NP)s grants therapeutic access to developing stem cell populations impacted by these classes of disease. Delivery of editing reagents in these NPs administered before birth have yielded encouraging results in preclinical mouse models of monogenic diseases. To translate this strategy clinically, the safety and efficacy of this strategy in larger animals will be necessary. We performed a pilot biodistribution study in 3 fetal non-human primates (NHPs) in mid-gestation examining systemic delivery of

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Gu, Xu‐rui, Yifan Tai, Zhen Liu, et al. "Layer‐by‐layer Assembly of Renal‐targeted Polymeric Nanoparticles for Robust Arginase‐2 Knockdown and Contrast‐induced Acute Kidney Injury Prevention." Advanced Healthcare Materials, April 30, 2024. http://dx.doi.org/10.1002/adhm.202304675.

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AbstractThe mitochondrial enzyme arginase‐2 (Arg‐2) is implicated in the pathophysiology of contrast‐induced acute kidney injury (CI‐AKI). Therefore, Arg‐2 represents a candid target for CI‐AKI prevention. Here, we developed layer‐by‐layer (LbL) assembled renal‐targeting polymeric nanoparticles to efficiently deliver small interfering RNA (siRNA), knockdown Arg‐2 expression in renal tubules, and evaluated prevention of CI‐AKI. Firstly, near‐infrared dye‐loaded poly(lactic‐co‐glycolic acid) (PLGA) anionic cores were electrostatically‐coated with cationic chitosan (CS) to facilitate the adsorpti

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Ismail, A. M., R. A. Nasr, and Talaat A. Hameed. "Fabrication and characterization of (PVDF/PEO)/AgBiSe₂ polymeric membrane with enhanced visible light photocatalytic performance." Journal of Applied Polymer Science, August 31, 2023. http://dx.doi.org/10.1002/app.54638.

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AbstractDriven by the visible band gap, silver bismuth selenide (AgBiSe2) was loaded in PVDF/PEO blend to enhance the photodegradation of Maxilon blue dye. AgBiSe2 nanoparticles were successfully synthesized by facile solvothermal approach and then loaded to PVDF/PEO (80/20) by 10, 20, and 30 wt%, by evaporative casting method. The X‐ray results in tandem with the Fourier transform infrared (FTIR) established the successful fabrication of (PVDF/PEO)/x(AgBiSe2) polymer nanocomposites. The X‐ray analysis verified the formation of hexagonal AgBiSe2 of a crystallite size ranging from 14.3 to 23.24

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Delledonne, Andrea, Elisa Guazzelli, Silvia Pescina, et al. "Amphiphilic Fluorinated Unimer Micelles as Nanocarriers of Fluorescent Probes for Bioimaging." August 28, 2023. https://doi.org/10.1021/acsanm.3c02300.

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The unique self-assembly properties of unimer micelles are exploited for the preparation of fluorescent nanocarriers embedding hydrophobic fluorophores. Unimer micelles are constituted by a (meth)acrylate copolymer with oligoethyleneglycol and perflurohexylethyl side chains (PEGMA90-co-FA10) in which the hydrophilic and hydrophobic comonomers are statistically distributed along the polymeric backbone. Thanks to hydrophobic interactions in water, the amphiphilic copolymer forms small nanoparticles (<10 nm), with tunable properties and functionality. An easy procedure for the encapsulation of

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Simone, Silvia, Francesco Galiano, Mirko Faccini, et al. "Preparation and Characterization of Polymeric-Hybrid PES/TiO2 Hollow Fiber Membranes for Potential Applications in Water Treatment." April 4, 2017. https://doi.org/10.3390/fib5020014.

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In this work, poly(ethersulfone) (PES) ultrafiltration (UF) hollow fibers (HF) were modified by introducing TiO2 nanoparticles (TiO2-NPs) in the polymeric dope, to endow them with photocatalytic properties. Different dope compositions and spinning conditions for producing "blank" PES UF fibers with suitable properties were investigated. PEO–PPO–PEO (Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol, Pluronic® (Sigma-Aldrich, Milan, Italy) was finally selected as the additive and a suitable dope composition was identified. After the detection of an appropriate dope c

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Chepurna, O. M., A. Yakovliev, R. Ziniuk, et al. "Core–shell polymeric nanoparticles co-loaded with photosensitizer and organic dye for photodynamic therapy guided by fluorescence imaging in near and short-wave infrared spectral regions." Journal of Nanobiotechnology 18, no. 1 (2020). http://dx.doi.org/10.1186/s12951-020-0572-1.

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Ueya, Yuichi, Masakazu Umezawa, Yuka Kobayashi, et al. "Effects of hydrophilic/hydrophobic blocks ratio of PEG-<i>b</i>-PLGA on Emission Intensity and Stability of Over-1000 nm Near-Infrared Fluorescence Dye-Loaded Polymeric Micellar Nanoparticles." Analytical Sciences, 2021. http://dx.doi.org/10.2116/analsci.21p283.

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Ueya, Yuichi, Masakazu Umezawa, Yuka Kobayashi, et al. "Effects of hydrophilic/hydrophobic blocks ratio of PEG-<i>b</i>-PLGA on Emission Intensity and Stability of Over-1000 nm Near-Infrared Fluorescence Dye-Loaded Polymeric Micellar Nanoparticles." Analytical Sciences, 2021. http://dx.doi.org/10.2116/analsci.21p283.

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Tutty, Melissa Anne, Gabrielle Vella, Antje Vennemann, Martin Wiemann, and Adriele Prina-Mello. "Evaluating nanobiomaterial-induced DNA strand breaks using the alkaline comet assay." Drug Delivery and Translational Research, May 25, 2022. http://dx.doi.org/10.1007/s13346-022-01178-7.

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AbstractDue to their unique chemical and physical properties, nanobiomaterials (NBMs) are extensively studied for applications in medicine and drug delivery. Despite these exciting properties, their small sizes also make them susceptible to toxicity. Whilst nanomaterial immunotoxicity and cytotoxicity are studied in great depth, there is still limited data on their potential genotoxicity or ability to cause DNA damage. In the past years, new medical device regulations, which came into place in 2020, were developed, which require the assessment of long-term NBM exposure; therefore, in recent ye

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Sayana, K. V., K. Prajwal, K. J. Deeksha, B. Vishalakshi, and T. Vishwanath. "Magnetized CNTs incorporated MBA cross‐linked guar gum nano‐composite for methylene blue dye removal." Journal of Applied Polymer Science, November 8, 2023. http://dx.doi.org/10.1002/app.54868.

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AbstractIn the present work, a magnetized multiwalled carbon nanotube dispersed in chemically cross‐linked gaur gum was developed as a nano‐composite adsorbent material for the removal of dye from wastewater. The gaur gum, a bio‐macromolecule was chemically modified by cross‐linking with methylene bis‐acrylamide in the presence of sodium hydroxide as a novel approach to prepare the gel matrix. The magnetite nanoparticles loaded multiwalled carbon nanotubes were dispersed in methylene bis‐acrylamide cross‐linked gaur gum gel during gelation. The nano‐composite was characterized for morphologica

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Jin, Qiaoli, and Qin Pan. "Nanoprodrugs encapsulated with mesoporous silica nanoparticles for combined with photothermal therapy for the treatment and care of gastric cancer." Materials Research Express, November 2, 2022. http://dx.doi.org/10.1088/2053-1591/ac9fad.

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Abstract In this study, mesoporous silica nanoparticles (MSNs) were surface-modified with polymer poly(HEMA-co-PEGMA via surface-initiated atom transfer radical polymerization and a multifunctional nanoplatform MSNP@poly(HEMA-co-PEGMA-g-doxorubicin (DOX)/ Rhodamine 6G (R6G) was developed to combine photothermal (PTT) and chemotherapy therapy effectively. PTT induced by near-infrared (NIR) radiations might further destroy gastric cancer cell lines while the small-dye molecule was co-loaded into the MSNP pores. A 65 % higher cumulative drug release over 50-h occurs when the cis-aconitic anhydrid

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