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1

DAINO, GIANLUCA. "Characterization of Ebola virus VP35-dsRNA binding for drug development against Ebola virus disease." Doctoral thesis, Università degli Studi di Cagliari, 2017. http://hdl.handle.net/11584/248693.

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The Ebola virus (EBOV) VP35 protein plays an important role in the inhibition of the initial innate immune responses to EBOV infection leading to Ebola virus disease development. In fact, VP35 interaction with the RIG-I like receptors (RLR) cascade components inhibits the interferon (IFN) production, impeding proper host immune response. Hence, it has been shown that VP35 is a validate drug target. Full-length His-tagged recombinant VP35 (rVP35) has been previously expressed in prokaryotic system and used to validate a biochemical pull-down assay for the screening of small molecules targeted t
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2

Dia, Emilia. ""Ebola har nu nått Europa" : En kritisk diskursanalys av nyhetsrapporteringen om ebola i svenska medier." Thesis, Stockholms universitet, JMK, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-120325.

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Genom kritiska diskursanalyser ämnar studien att undersöka nyhetsrapporteringen av ebola i de svenska tidningarna Dagens Nyheter och Aftonbladet. Delvis för att få förståelse för hur mediepanik skapas, men även hur relationen mellan nyhetsläsaren och den lidande konstrueras. Undersökningsperioden för studien är oktober 2014. Den tidigare forskningen som belyses i denna undersökning är studier om nyhetsrapporteringar kring svininfluensan, SARS-smittan och salmonellabakterien. Dessa visar på att de intensiva perioderna i nyhetsrapporteringen ofta innefattar användningen av visuella och lingvisti
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3

Miller, Michele. "Development and Validation of Virus and Ebola Misconceptions Assessment (VirEMiA): Ebola Virus Misconceptions in College Students." Wright State University / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=wright1459333659.

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4

LaTouche, Alina S. "East Harlem seniors' knowledge about ebola." Thesis, Icahn School of Medicine at Mount Sinai, 2016. http://pqdtopen.proquest.com/#viewpdf?dispub=10107190.

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<p>Older adults&rsquo; knowledge and perceptions about Ebola have not been previously explored in the literature. A survey, administered during the Ebola outbreak in 2014, was performed to capture East Harlem senior residents&rsquo; knowledge about Ebola and identify their major sources of information, their self-reported levels of trust in city officials, and whether or not they would follow officials&rsquo; directions. Results using frequency testing showed that senior respondents were not knowledgeable about disease transmission. The major trusted sources of information identified were tele
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5

Seiler, Nina. "Inkubationszeit und Übertragungsparameter der Ebola-Viruskrankheit." [S.l. : s.n.], 2008.

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6

Lennemann, Nicholas Joseph. "Biochemical characterization of Ebola virus GP." Diss., University of Iowa, 2014. https://ir.uiowa.edu/etd/3127.

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Filoviruses cause sporadic outbreaks of highly lethal hemorrhagic fever throughout central Africa. Virus entry is mediated by the sole viral glycoprotein, GP. Furthermore, GP is the main target for neutralizing antibodies. Thus, a better understanding of GP and its functions is critical for the development of antivirals and vaccines. GP contains a high number of N- and O-linked glycans, which shield the majority of the protein. These glycans are required for cell surface interactions with C-type lectins that mediate internalization of the virus. We found that GP1, but not GP2, N-linked glycans
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7

Dapiaggi, F. "MOLECULAR MODELING OF EBOLA VIRUS INHIBITORS." Doctoral thesis, Università degli Studi di Milano, 2018. http://hdl.handle.net/2434/545872.

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In this PhD thesis computational methods have been employed in order to study different biologically relevant systems. In the first part of the thesis two Ebola virus proteins were studied, namely Viral Protein 24 (VP24) and Viral Protein 35 (VP35), responsible for the inhibition of the immune response . After a brief theoretical introduction to the main computational methods employed in the thesis, a study of VP35 in complex with small organic molecules is presented. These compounds are able to inhibit the interaction between VP35 and viral nucleoprotein. This study confirms the experimenta
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8

Elmberg, Emma, and Mathilda Nordahl. "”Världen förlorar kampen mot ebola” : En kvantitativ innehållsanalys om hur ebola gestaltades i svensk storstadspress hösten 2014." Thesis, Linnéuniversitetet, Institutionen för medier och journalistik (MJ), 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-45042.

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9

Victoriano, Analisa Machado. "Ébola: uma revisão bibliográfica." Bachelor's thesis, [s.n.], 2020. http://hdl.handle.net/10284/9282.

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Projeto de Graduação apresentado à Universidade Fernando Pessoa para obtenção do grau de Licenciada em Enfermagem<br>O vírus Ébola é um agente patogénico causador de uma doença sistémica, grave e com alta taxa de mortalidade em humanos e primatas não-humanos. Foi descoberto pela primeira vez em 1976 na República Democrática do Congo. Existem cinco espécies conhecidas do vírus, das quais quatro foram identificadas na África Equatorial. Uma vez que entra na população humana a transmissão ocorre principalmente pelo contato com fluídos corporais contaminados. O vírus causa uma supressão do si
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10

Gasquet, Clélia. "Une géographie de la fièvre hémorragique à virus Ebola : représentations et réalités d'une maladie émergente au Gabon et en République du Congo." Paris 10, 2010. http://www.theses.fr/2010PA100131.

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La fièvre hémorragique à virus Ebola est une maladie qui constitue une menace pour les populations d'Afrique Centrale, notamment en milieu rural forestier. Au Gabon et en République du Congo, où 7 épidémies ont sévit entre 1994 et 2005, elle y est devenue un problème de santé publique. Cette zoonose émerge chez l'homme lors d'un contact direct avec un animal contaminé, une carcasse ou un vecteur du virus. L'émergence est directement liée aux pratiques ancestrales des lieux (chasse, cueillette, etc. ). La contamination inter humaine a lieu lors d'un contact direct avec les fluides corporels d'u
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Mbala-Kingebeni, Placide. "Virus Ebola à l’interface homme – faune sauvage et réservoir animal des virus Ebola en République Démocratique du Congo." Thesis, Montpellier, 2019. http://www.theses.fr/2019MONTT035.

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Chaque épidémie de la maladie à virus Ebola résulte très probablement d'événements zoonotiques indépendants. Plus de quatre décennies après la première identification du virus Ebola, son réservoir demeure encore inconnu. Nous avons montré dans ce travail que la prévalence du virus Ebola dans la faune sauvage était très faible avec une présence d’anticorps anti-virus Ebola (Zaïre et/ou Sudan) chez moins de 1% des chauves-souris testées de la RDC, Guinée et Cameroun ; et de 0% chez les primates non humains de la RDC, Cote d’Ivoire et Cameroun, en période inter-épidémique. Aucun anticorps n’a été
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12

Schneider, Brian J. (Brian Joseph) 1973. "Protein dissection of the Ebola virus glycoprotein." Thesis, Massachusetts Institute of Technology, 1998. http://hdl.handle.net/1721.1/88820.

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13

Lindström, Jöran. "Covid-19 i Afrika: Beredskap efter ebola." Thesis, Högskolan i Skövde, Institutionen för hälsovetenskaper, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-20045.

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Introduktion Afrika har haft flera utbrott av ebola (EVD). Det Västafrikanska EVD-utbrottet 2014-2016 var det mestförödande med mer än 28 000 fall och mer än 11 000 dödsfall. Utbrottet började i Guinea och spredsöver gränsen till Sierra Leone och Liberia. 2018-2020 var det ett utbrott av EVD i DemokratiskaRepubliken Kongo (DRC) som spreds till Uganda. På grund av utbrotten av EVD har de drabbadeländerna byggt upp kapacitet att hantera epidemier. Syfte Syftet med studien är att beskriva den kapacitet som byggts upp i respons till EVD-utbrott, och hurkapaciteten har varit till nytta för staterna
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14

Nilsson, Marina. "Utvecklingen av nya vacciner mot ebolafeber : Erfarenheter efter senaste utbrottet i Kongo 2018." Thesis, Linnéuniversitetet, Institutionen för kemi och biomedicin (KOB), 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-93287.

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Introduction: Since the first outbreaks of Ebola virus disease 1976 in the Democratic Republic of the Congo (DRC) and Sudan there has been recurrent epidemics. The biggest outbreak so far hit West Africa between 2013-2016 when at least 28 600 people were estimated to have been infected and approximately 11 300 died in the most severely affected countries Guinea, Sierra Leone and Liberia. Ebola hemorrhagic fever (EHF) or Ebola virus disease (EVD) is caused by a virus that together with the Marburg virus belongs to the Filovirus family. The Ebola virus can cause hemorrhagic bleeding, has a rapid
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15

Karlsson, Johanna. "Kunskapsläget om ebola bland Örebros läkarstudenter ht 2014." Thesis, Örebro universitet, Institutionen för läkarutbildning, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-42968.

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16

Foster, Felicity Laurel. "Contagion and Violence | "No Ebola in West Point!"." Thesis, The American University of Paris (France), 2019. http://pqdtopen.proquest.com/#viewpdf?dispub=13871614.

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17

Ahmadi, Fard Ala. "Ebola hemorrhagic fever: outbreaks, modeling, and vaccine development." Kansas State University, 2016. http://hdl.handle.net/2097/32649.

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Master of Science<br>Department of Biological & Agricultural Engineering<br>Caterina M. Scoglio<br>Lisa R. Wilken<br>Between the years 2014 and 2015, the world experienced a catastrophic outbreak of Ebola virus, which killed over 26,000 people. Several authorities and organizations actively participated in fighting the epidemic. Infectious disease modelers proved to be invaluable towards this goal. This report provides a background on the Ebola epidemic in West Africa and reviews the biological features of the Ebola virus. Moreover, this report applies a new model for Ebola propagation using d
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18

Lin, Kaisen. "Aerosolization of Ebola Virus Surrogates in Wastewater Systems." Thesis, Virginia Tech, 2016. http://hdl.handle.net/10919/73043.

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Recent studies have shown that Ebola virus can persist in wastewater, and the potential for the virus to be aerosolized and pose a risk of inhalation exposure has not been evaluated. We considered this risk for three wastewater systems: toilets, a lab-scale model of an aeration basin, and a lab-scale model of converging sewer pipes. We measured the aerosol size distribution generated by each system, spiked Ebola virus surrogates into each system, and determined the emission rate of viruses into the air. While the number of aerosols released ranged from 105 to 107 per flush from the toilets or
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19

Leroy, Éric. "Infection asymptomatique de l'homme par le virus ebola." Paris 6, 2000. http://www.theses.fr/2000PA066292.

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La fievre hemorragique ebola, due a un virus enveloppe a simple brin d'arn non segmente de polarite negative, est une maladie d'evolution aigue qui tue environ 70% des malades. Les desordres physiopathologiques et immunitaires qu'elle entraine sont essentiellement lies a l'infection des monocytes et des cellules endotheliales. Durant les trois epidemies survenues au gabon entre 1995 et 1997, nous avons identifie sept personnes qui n'ont jamais developpe de symptomes malgre des contacts physiques avec certains liquides biologiques infectieux. L'infection par le virus ebola fut d'abord suspectee
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20

Lee, Christopher T. "Critical Heat Stress Evaluation In Two Ebola Ensembles." Scholar Commons, 2016. http://scholarcommons.usf.edu/etd/6299.

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Ebola, a type of filovirus that causes hemorrhagic fevers, dominated global headlines in 2014 when the largest Ebola epidemic in history took place in West Africa. Healthcare practitioners were at particular risk of contracting Ebola while taking care of patients with the disease because they were easily exposed to bodily fluids such as blood, urine, saliva, and feces, quite often in the intensive care unit (ICU). While personal protective equipment (PPE) protects the healthcare practitioner by providing an effective barrier against the virus, users were also at risk for heat stress because of
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21

Brody-Moore, Peter. "Bayesian Hierarchical Meta-Analysis of Asymptomatic Ebola Seroprevalence." Scholarship @ Claremont, 2019. https://scholarship.claremont.edu/cmc_theses/2228.

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The continued study of asymptomatic Ebolavirus infection is necessary to develop a more complete understanding of Ebola transmission dynamics. This paper conducts a meta-analysis of eight studies that measure seroprevalence (the number of subjects that test positive for anti-Ebolavirus antibodies in their blood) in subjects with household exposure or known case-contact with Ebola, but that have shown no symptoms. In our two random effects Bayesian hierarchical models, we find estimated seroprevalences of 8.76% and 9.72%, significantly higher than the 3.3% found by a previous meta-analysis of t
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22

Leigh, Laurasona. "Behavioral and Environmental Attributes of Ebola Epidemic in West Africa and United States Emergency Nurses’ Motivation to Protect Themselves against Ebola Infection." University of Toledo / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1470411786.

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23

Martin, Baptiste. "Méthyltransférases des filovirus et autres mononégavirus : caractérisation, originalités et drug design." Thesis, Aix-Marseille, 2017. http://www.theses.fr/2017AIXM0258.

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Les virus appartenant à l’ordre des Mononegavirales possèdent une « large » protéine L, responsable du cycle réplication/transcription et de maturation des ARNs. Six domaines conservés portent les différentes activités de cette protéine dont le site catalytique d’une activité méthyltransférase (MTase) de la coiffe. La coiffe est une structure chimique constituée d’une guanosine méthylée en position N7 reliée à l’extrémité 5’ des ARNm par une liaison 5’-5’ triphosphate. Une seconde méthylation est également présente en position 2’O du ribose du premier nucléotide de l’extrémité 5’ de l’ARNm. Ce
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24

Weik, Michael. "Untersuchung cis-aktiver Elemente im Genom des Ebola-Virus." [S.l.] : [s.n.], 2001. http://archiv.ub.uni-marburg.de/diss/z2002/0194/.

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Änäkkälä, Nicola. "Seroprevalence study on Ebola Virus in patients in Uganda." Thesis, Örebro universitet, Institutionen för hälsovetenskap och medicin, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-44931.

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Gjyljeta, Fifa. "Ebola Virus (EVD) through the lenses of news articles." Thesis, Linnéuniversitetet, Institutionen för statsvetenskap (ST), 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-39539.

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Media in modern society uses their influence and power to frame social phenomenon in society from political elections, health crisis, war to terrorism etc. The aim of this study is on a global level to observe how selected newspapers have portrayed Ebola virus (EVD). The conceptual framework presented will be a mixture of concepts based in Peace and Development studies and Media studies with an emphasis on the first as this thesis is iwhitn Peace and Development Studies.   This study will be a qualitative study, where selected articles are observed and analyzed with the help of a content analy
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Montazeri, Shahtori Narges. "Quantifying the impact of contact tracing on ebola spreading." Thesis, Kansas State University, 2016. http://hdl.handle.net/2097/34540.

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Master of Science<br>Department of Electrical and Computer Engineering<br>Faryad Darabi Sahneh<br>Recent experience of Ebola outbreak of 2014 highlighted the importance of immediate response to impede Ebola transmission at its very early stage. To this aim, efficient and effective allocation of limited resources is crucial. Among standard interventions is the practice of following up with physical contacts of individuals diagnosed with Ebola virus disease -- known as contact tracing. In an effort to objectively understand the effect of possible contact tracing protocols, we explicitly develop
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Hanson, Jessi, Patrick Seeco Faley, and Megan Quinn. "Analysis of the Liberian Ebola Survivors Support System (ESSS)." Digital Commons @ East Tennessee State University, 2017. https://dc.etsu.edu/etsu-works/6786.

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A systems theoretical analysis to capture the evolution and transition of the network systems supporting Ebola survivors and their affected communities, during the 2014-15 Ebola outbreak and recovery phases. The qualitative analysis includes a literature review, archival review, and interviews with representatives of key actors operating in strategic action fields. This paper uses a series of Diagrams that visually illustrate the various complex phases and their network changes that occurred and were established during the outbreak. This case analysis provides crucial phase information that bo
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Hanson, Jessi, Alexis Decosimo, and Megan Quinn. "Diminished Quality of Life among Women affected by Ebola." Digital Commons @ East Tennessee State University, 2016. https://dc.etsu.edu/etsu-works/6867.

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This article analyzes data collected from Liberian women afflicted by the Ebola virus disease, survivors of the virus and noninfected persons living in Ebola-affected homes. This research is one of the first statistical analyses examining factors diminishing quality of life: negative experiences, stigma, and psychosocial symptoms among females affected by the virus after the outbreak. The research presents a thorough literature review, including research related to other infectious diseases like HIV/AIDS, to inform the gap in studies on Ebola’s effects on quality of life. Women who are Ebola v
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Scully, William. "A Critical Analysis of the Ebola and Marburg Viruses." Miami University Honors Theses / OhioLINK, 2004. http://rave.ohiolink.edu/etdc/view?acc_num=muhonors1111685379.

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Gopalakrishnan, Arjun. "Probabilistic Analysis of Contracting Ebola Virus Using Contextual Intelligence." Thesis, University of North Texas, 2017. https://digital.library.unt.edu/ark:/67531/metadc984182/.

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The outbreak of the Ebola virus was declared a Public Health Emergency of International Concern by the World Health Organisation (WHO). Due to the complex nature of the outbreak, the Centers for Disease Control and Prevention (CDC) had created interim guidance for monitoring people potentially exposed to Ebola and for evaluating their intended travel and restricting the movements of carriers when needed. Tools to evaluate the risk of individuals and groups of individuals contracting the disease could mitigate the growing anxiety and fear. The goal is to understand and analyze the nature of ris
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Escudero, Pérez Beatriz. "The role of shed GP in Ebola virus pathogenicity." Thesis, Lyon, École normale supérieure, 2014. http://www.theses.fr/2014ENSL0933/document.

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Au cours de l’infection par le virus Ebola (EBOV), plusieurs glycoprotéines solubles sont massivement libérées à partir de cellules infectées mais le rôle précis de ces protéines virales n’a pas encore été identifié. Nous émettons l'hypothèse que l'altération de l’hémostase et du système et vasculaires observée au cours de l'infection à virus Ebola pourrait être, au moins en partie causée par ces glycoprotéines solubles. Ainsi pour la première fois, nous avons identifié les cibles cellulaires de la protéine soluble « shed GP » d’Ebola et nous avons démontré que sa partie glycosylé peut activer
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Fuhrmann, Didier. "Les fièvres hémorragiques africaines : les virus Lassa - Ebola - Marbourg." Strasbourg 1, 1988. http://www.theses.fr/1988STR15028.

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Sandersfeld, Lindsay Marie Maury Wendy J. "Identification of ebola glycoprotein mutants that exhibit increased transduction efficiency." [Iowa City, Iowa] : University of Iowa, 2009. http://ir.uiowa.edu/etd/428.

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Modrof, Jens. "Strukturelle Charakteristika des Ebola-Virus-VP30 und deren funktionelle Bedeutung." [S.l.] : [s.n.], 2002. http://archiv.ub.uni-marburg.de/diss/z2002/0078/.

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Mehedi, Masfique. "Ebola virus RNA editing:Characterization of the mechanism and gene products." American Society of Microbiology, 2011. http://hdl.handle.net/1993/11465.

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Ebola virus (EBOV) is an enveloped, negative-sense single-stranded RNA virus that causes severe hemorrhagic fever in humans and nonhuman primates. The EBOV glycoprotein (GP) gene encodes multiple transcripts due to RNA editing at a conserved editing site (ES) (a hepta-uridine stretche). The majority of GP gene transcript is unedited and encodes for a soluble glycoprotein (sGP); a defined function has not been assigned for sGP. In contrast, the transmembrane glycoprotein (GP1,2) dictates viral tropism and is expressed through RNA editing by insertion of a nontemplate adenosine (A) residue. Hyp
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Rodríguez, Morales Alfonso J., Daniel E. Henao, Tulio B. Franco, Percy Mayta-Tristan, Toloza Patricio Alfaro, and Mondolfi Alberto E. Paniz. "Ebola: A latent threat to Latin America. Are we ready?" Elsevier B.V, 2014. http://hdl.handle.net/10757/334794.

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Garcia-Dorival, G. I. "Investigation of the interaction between Ebola virus and the host." Thesis, University of Liverpool, 2016. http://livrepository.liverpool.ac.uk/3002887/.

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Ebola viruses cause viral haemorrhagic fever in humans and non human primates. Due to the severity of their symptoms, the lack of an approved treatment or vaccine, and the mechanism of transmission, these viruses have been classified as containment level 4 (CL4) pathogens. In December 2013, an Ebola virus outbreak initiated in West Africa, which lasted more than two years, and has been considered the worst outbreak in the history of the Ebola viruses. More than twenty-seven thousand people had a positive diagnosis of infection with more than eleven thousand confirmed dead. This outbreak highli
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Sandersfeld, Lindsay Marie. "Identification of ebola glycoprotein mutants that exhibit increased transduction efficiency." Thesis, University of Iowa, 2009. https://ir.uiowa.edu/etd/428.

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Gene delivery via lentiviruses can yield long term expression of transgenes. Specificity of host cell targeting by viral vectors occurs primarily through viral glycoprotein (GP)/cellular receptor interactions. Ebola virus (EBOV) GP has broad tropism for a variety of cell types making this viral GP a potentially useful reagent for delivery of gene therapy. However, titers of EBOV GP pseudotyped lentiviruses are insufficient for practical use in clinical applications. Enhancement of EBOV-GP pseudotyped titers by as little as half a log might yield clinically applicable titers. In an alanine scan
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Rhein, Bethany Ann. "Ebola virus: entry, pathogenesis and identification of host antiviral activities." Diss., University of Iowa, 2015. https://ir.uiowa.edu/etd/6629.

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Ebola virus (EBOV) is a member of the Filoviridae family of highly pathogenic viruses that cause severe hemorrhagic fever and is the causative agent of the 2014 West Africa outbreak. Currently, there are no approved filovirus vaccines or treatments to combat these sporadic and deadly epidemics. One target for EBOV antiviral therapy is to block viral entry into host cells. Recently, phosphatidylserine (PtdSer) receptors, primarily known for their involvement in the clearance of dying cells, were shown to mediate entry of enveloped viruses including filoviruses. The PtdSer receptors, T-cell immu
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Danet, Nicolas. "Molecular characterisation of the recombinant Vesicular Stomatitis Virus- ZEBOV-GP virus, prototype vaccine against Ebola virus." Thesis, Lyon, 2019. http://www.theses.fr/2019LYSE1009/document.

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Ebolavirus (EBOV) est un filovirus responsable de fièvres hémorragiques virales sévères chez l’humain, qui peuvent être létales dans 90% des cas. L’actuelle épidémie en République Démocratique du Congo et l’ampleur démesurée de l'épidémie de 2014-2016 en Afrique de l’Ouest, qui a causé la mort de plus de 11 000 personnes, ont poussé les agences sanitaires internationales à tester plusieurs approches thérapeutiques afin d’essayer d’endiguer rapidement la propagation virale et de limiter la mortalité liée au virus lors de futures épidémies. Parmi toutes les stratégies testées, le virus recombina
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Magro, Laura. "Microfluidique papier : de la physique des écoulements au diagnostic du virus Ebola en Guinée." Thesis, Paris 6, 2016. http://www.theses.fr/2016PA066281/document.

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Les propriétés du papier - pompe capillaire, prix et disponibilité - lui permettent de répondre à tout type de contraintes logistiques et économiques d'un diagnostic médical de terrain. En amont de l'application, nous avons étudié les écoulements dans des géométries confinées par des barrières de cire. Une focalisation hydrodynamique associée à l'évaporation, crée un effet de concentrateur atteignant un facteur d'amplification de 1000. La continuité du diagnostic depuis le terrain jusqu'au laboratoire est assurée par des dispositifs hybrides papier-microsystèmes. Dans cette thèse, l'élution d'
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DANFÁ, Lassana. "Alteridade, racismo e representações sociais: o caso do ebola no Brasil." Universidade Federal de Pernambuco, 2015. https://repositorio.ufpe.br/handle/123456789/17791.

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Submitted by Fabio Sobreira Campos da Costa (fabio.sobreira@ufpe.br) on 2016-09-02T14:25:01Z No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) Versão final Dissertação Lassana CD.pdf: 1870227 bytes, checksum: 07b7ee23503d967524b8be573e306d58 (MD5)<br>Made available in DSpace on 2016-09-02T14:25:01Z (GMT). No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) Versão final Dissertação Lassana CD.pdf: 1870227 bytes, checksum: 07b7ee23503d967524b8be573e306d58 (MD5) Previous issue date: 2015-02-23<br>CAPEs<br>O
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Rijal, Pramila. "A study of human monoclonal antibodies to Influenza and Ebola viruses." Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:ce156cca-cc96-407a-8a3f-779e5c25f445.

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This thesis describes an analysis of the B cell repertoire in humans in response to infection or vaccination with Influenza or Ebola. We isolated monoclonal antibodies (mAbs) from individuals using single B cell cloning and PCR technology, and defined their epitopes, binding characteristics and neutralisation properties. As summarised by Thomas Francis in 1960, we found that the secondary B cell response to Influenza is largely determined by the primary response to the virus that the donor was exposed to in childhood. In some individuals this can lead to focusing of the polyclonal antibody res
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Kane, Michaela Lynn. "Covering an Epidemic: The Ebola Virus and AIDS in the News." Thesis, The University of Arizona, 2015. http://hdl.handle.net/10150/579331.

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This paper aims to investigate media coverage of disease outbreaks and epidemics by focusing on the 2014 Ebola outbreak and the AIDS epidemic as specific examples. Using news articles and scientific reports, this paper investigates the biology and history of both diseases to provide context and analyze how news coverage changes. A study of articles published by news organizations such as The New York Times, The Economist, TIME, Associated Press, and The Los Angeles Times reveals that media coverage of disease outbreaks and epidemics follows three different "waves": early scientific reporting,
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46

Sumo, Augustine M. "Coping With the Threat of Ebola in Monrovia: A Case Study." ScholarWorks, 2017. https://scholarworks.waldenu.edu/dissertations/4817.

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In early 2014, 3 West African states of Guinea, Liberia, and Sierra Leone made news headlines when Ebola virus disease (EVD) ravaged the sub-region. The Liberian government was ill-equipped to efficiently contain EVD outbreak due to inadequate training for hospitals and healthcare workers. The government's mandatory cremation policies and the banning of public gatherings significantly contributed to the spread of EVD. EVD infected 10,666 and 4,808 died from the disease in the first 6 months of the epidemic. Using Bandura's Social Cognitive Theory (SCT) as the theoretical framework, the purpose
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Kamara, Kandeh. "Predictors and Risk Factors of Ebola Virus Disease in Sierra Leone." ScholarWorks, 2019. https://scholarworks.waldenu.edu/dissertations/7677.

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Sierra Leone had the highest number of cases of Ebola virus disease in history during the 2014 Ebola epidemic. The purpose of this quantitative, cross-sectional study was to examine the relationship between sociocultural and behavioral risk factors and Ebola status among women and men ages 15 to 49 years in Sierra Leone. The ecological model served as the theoretical framework. Secondary data were collected from the Sierra Leone Ebola Disease Survey. Results of chi-square tests revealed that attending a funeral (p = .001), touching a dead body at a funeral (p = .023), contact with a sick perso
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48

Cederblad, Anna, and Henrik Hägg. "Nurses educating patients and relatives about viral hemorrhagic fever diseases : A qualitative study in Uganda." Thesis, Uppsala universitet, Institutionen för folkhälso- och vårdvetenskap, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-253503.

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Introduction: Recent Ebola epidemic in West Africa have put viral hemorrhagic fever diseases in the spotlight. Uganda has had several outbreaks throughout the years, which have successfully been managed. Nurses’ patient education plays an important role in the work to increase public awareness about viral hemorrhagic fever diseases. Objectives: To assess how nurses at the emergency department educate the patients and relatives about the viral hemorrhagic fever diseases. Methods: An explorative and descriptive qualitative study with qualitative approach have been used. In-depth interviews with
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Christiansson, Camilla, and Ellen Ferm. "DEN FRUKTADE BLÖDARFEBERN : En studie om två svenska dagstidningars framställning av ebola." Thesis, Högskolan i Halmstad, Akademin för hälsa och välfärd, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-27699.

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Syfte och frågeställning: Att undersöka hur två svenska nyhetstidningar valt att skildra en nyhet under vald period. Detta görs genom att besvara följande frågeställning: På vilket sätt skildrar Dagens Nyheter och Svenska Dagbladet ebolaviruset i sina tidningsartiklar från 1 maj 2014 till och med den 31 oktober 2014? Metod och material: Kvantitativ innehållsanalys på samtliga artiklar publicerade i DN och SvD under perioden 1 maj 2014 till och med 31 oktober 2014 samt diskursanalys på sex artiklar. Huvudresultat: I studien framkom det en tydlig förändring i artiklarna under hela undersökningsp
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Hohnstein, Nicole M. "Determining the Reservoir Species of Zaire Ebola Virus: A Proposed Epidemiological Survey." Scholarship @ Claremont, 2016. http://scholarship.claremont.edu/cmc_theses/1394.

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Ebola virus (EBOV) is a re-emerging zoonotic virus (it is transmitted between animals and humans) that causes acute hemorrhagic fever and a high fatality rate in humans. First reported in 1976 in the Democratic Republic of the Congo (formerly Zaire), the virus is transmitted between humans through direct contact with body fluids of an infected person, causing fever, weakness, diarrhea, abdominal pain, cramping, nausea and vomiting in those affected. There is neither a licensed vaccine nor an approved treatment for Ebola virus in human patients. The reservoir species for Ebola virus is similarl
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