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1

BAŞER, Sümeyye, Salih MAÇİN, Gülay MAÇİN, and Serra ÖRSTEN. "An overview of the genetic diversity of Echinococcus granulosus sensu lato in Turkey." Journal of Contemporary Medicine 12, no. 6 (2022): 1025–29. http://dx.doi.org/10.16899/jcm.1134747.

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Echinococcus granulosus is a parasite that lives as a host in animals and humans, causes great economic damage and poses a serious threat to health. Morphological differences and intermediate host preference are used to distinguish the species of this parasite. Ten genotypes and lion strains of Echinococcus granulosus have been identified in molecular studies to date. It contributes to the fact that the effects of cystic echinococcosis detected in humans and the disease process caused by different genotypes can be handled differently. In genetic diversity analysis, species were classified as E
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2

ALVAREZ ROJAS, C. A., D. EBI, C. G. Gauci, et al. "Microdiversity of Echinococcus granulosus sensu stricto in Australia." Parasitology 143, no. 8 (2016): 1026–33. http://dx.doi.org/10.1017/s0031182016000445.

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SUMMARYEchinococcus granulosus (sensu lato) is now recognized as an assemblage of cryptic species, which differ considerably in morphology, development, host specificity (including infectivity/pathogenicity for humans) and other aspects. One of these species, E. granulosus sensu stricto (s.s.), is now clearly identified as the principal agent causing cystic echinococcosis in humans. Previous studies of a small section of the cox1 and nadh1 genes identified two variants of E. granulosus s.s. to be present in Australia; however, no further work has been carried out to characterize the microdiver
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3

Konyaev, S. V., T. Yanagida, M. V. Ivanov, et al. "The first report on cystic echinococcosis in a cat caused by Echinococcus granulosus sensu stricto (G1)." Journal of Helminthology 86, no. 4 (2011): 391–94. http://dx.doi.org/10.1017/s0022149x1100054x.

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AbstractA case of cystic echinococcosis (CE) in a domestic cat is described from Saint Petersburg, Russia. Ultrasonography showed numerous cysts with hyperechoic walls and anechoic contents within the cat's abdominal cavity. Molecular identification based on mitochondrial DNA genes indicated that the causative agent was Echinococcus granulosus sensu stricto (G1 strain). This is the first report of CE in a cat caused by E. granulosus sensu stricto with molecular confirmation.
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4

Ali, V., E. Martinez, P. Duran, et al. "Echinococcus granulosus sensu stricto, Echinococcus ortleppi; and E. intermedius (G7) are present in Bolivia." Parasitology 147, no. 9 (2020): 949–56. http://dx.doi.org/10.1017/s0031182020000529.

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AbstractCystic echinococcosis (CE) is a zoonotic disease caused by a complex of species known as Echinococcus granulosus sensu lato. CE is endemic in Argentina, Chile, Peru, Uruguay and the South part of Brazil. In contrast, little is known regarding the presence of CE in Bolivia. In this study, 35 cysts isolated from livestock (mostly from the Department of La Paz) and 3 from humans (La Paz, Oruro and Potosi) were genetically characterized analysing the sequence of the cox1 gene (1609 bp). In total, 30 cysts (from La Paz, Cochabamba and Beni) were characterized as E. granulosus sensu stricto
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5

Soriano, S. V., N. B. Pierangeli, L. A. Pianciola, et al. "The optimum cut-off value to differentiate Echinococcus granulosus sensu stricto from other species of E. granulosus sensu lato using larval rostellar hook morphometry." Journal of Helminthology 89, no. 1 (2013): 1–8. http://dx.doi.org/10.1017/s0022149x13000473.

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AbstractCystic echinococcosis caused by Echinococcus granulosus sensu lato is one of the most important helminth zoonoses in the world; it affects both humans and livestock. The disease is endemic in Argentina and highly endemic in the province of Neuquén. Considerable genetic and phenotypic variation has been demonstrated in E. granulosus, and ten different genotypes (G1–G10) have been identified using molecular tools. Echinococcus granulosus sensu lato may be considered a species complex, comprised of E. granulosus sensu stricto (G1–G3), E. equinus (G4), E. ortleppi (G5) and E. canadensis (G
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6

Albani, Clara María, Giselle Fuentes, Cristina Lujan Ramírez, et al. "Anthelmintic Effect of Cannabidiol against Echinococcus granulosus sensu stricto." Tropical Medicine and Infectious Disease 9, no. 2 (2024): 35. http://dx.doi.org/10.3390/tropicalmed9020035.

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Cystic echinococcosis is a global parasitic zoonosis caused by infection with the larval stage of Echinococcus granulosus sensu lato. Cystic echinococcosis affects more than 1 million people worldwide, causing important economic costs in terms of management and livestock associated losses. Albendazole is the main drug used in treating human cystic echinococcosis. In spite of this, its low aqueous solubility, poor absorption, and consequently erratic bioavailability are the cause of its chemotherapeutic failures. Based on the described problem, new treatment alternatives urgently need to be dev
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7

Boufana, B., W. Lett, S. Lahmar, et al. "Canine echinococcosis: genetic diversity of Echinococcus granulosus sensu stricto (s.s.) from definitive hosts." Journal of Helminthology 89, no. 6 (2015): 689–98. http://dx.doi.org/10.1017/s0022149x15000395.

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AbstractCanids, particularly dogs, constitute the major source of cystic echinococcosis (CE) infection to humans, with the majority of cases being caused by Echinococcus granulosus (G1 genotype). Canine echinococcosis is an asymptomatic disease caused by adult tapeworms of E. granulosus sensu lato (s.l.). Information on the population structure and genetic variation of adult E. granulosus is limited. Using sequenced data of the mitochondrial cytochrome c oxidase subunit 1 (cox1) we examined the genetic diversity and population structure of adult tapeworms of E. granulosus (G1 genotype) from ca
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8

Gojwari, Tariq A., Tahleel A. Shera, Naseer A. Choh, et al. "Treatment of Hydatid Liver Disease: What does the evidence say." JMS SKIMS 19, no. 1 (2016): 5–11. http://dx.doi.org/10.33883/jms.v19i1.274.

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Cystic echinococcosis is a disease of animals and humans caused by the larval stage of of Echinococcus granulosus sensu lato and has a substantial public health impact globally. The condition is considered a neglected tropical disease (NTD) and neglected zoonotic disease (NZD), and prioritized by the World Health Organization (WHO) 1.Within the last 10 years, advancements have taken place in Echinococcus biology and genetics, including the delineation of new species within E.granulosus sensu lato (s.l.)2,3 and full sequencing of E. granulosus sensustricto. 2 Consequently, researchers are now p
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9

Hizem, A., S. M'rad, M. Oudni-M'rad, et al. "Molecular genotyping of Echinococcus granulosus using formalin-fixed paraffin-embedded preparations from human isolates in unusual tissue sites." Journal of Helminthology 90, no. 4 (2015): 417–21. http://dx.doi.org/10.1017/s0022149x15000516.

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AbstractCystic echinococcosis (CE) caused by Echinococcus granulosus remains a serious problem worldwide for issues relating to public health and the economy. The most predominantly affected sites are the liver and the lungs, but other organs such as the heart, the spleen and the peritoneum can also be infected. Access to cysts from uncommon sites has limited genomic and molecular investigations. In the present study, genotypes of E. granulosus sensu lato were identified from formalin-fixed paraffin-embedded tissues (FF-PETs) implicated in human CE. Tissue samples were obtained from 57 patient
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10

Alvarez Rojas, Cristian A., Dennis Ebi, Rodolfo Paredes, et al. "High intraspecific variability of Echinococcus granulosus sensu stricto in Chile." Parasitology International 66, no. 2 (2017): 112–15. http://dx.doi.org/10.1016/j.parint.2016.12.001.

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11

Bonelli, Piero, Silvia Dei Giudici, Angela Peruzzu, et al. "Genetic diversity of Echinococcus granulosus sensu stricto in Sardinia (Italy)." Parasitology International 77 (August 2020): 102120. http://dx.doi.org/10.1016/j.parint.2020.102120.

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12

Oudni-M’rad, Myriam, Selim M’rad, Amine Ksia, et al. "First molecular evidence of the simultaneous human infection with two species of Echinococcus granulosus sensu lato: Echinococcus granulosus sensu stricto and Echinococcus canadensis." Parasitology Research 115, no. 3 (2015): 1065–69. http://dx.doi.org/10.1007/s00436-015-4836-x.

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13

Brožová, A., I. Jankovská, V. Bejček, et al. "Echinococcus spp.: Tapeworms that Pose a Danger to Both Animals and Humans – a Review." Scientia Agriculturae Bohemica 48, no. 4 (2017): 193–201. http://dx.doi.org/10.1515/sab-2017-0026.

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Abstract Species of the genus Echinococcus (Cestoda; Taeniidae) are minute tapeworms of carnivores. Their larvae are known as hydatids (metacestode), which proliferate asexually in various mammals. Like the majority of cestodes, Echinococcus spp. require two different host species to complete their life cycle. Definitive hosts harbouring the adult cestodes in the small intestine are exclusively carnivores of the Canidae and Felidae families. A wide range of mammal species including humans is susceptible to infection by the metacestode of Echinococcus spp., which develops in their viscera. The
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14

Santucciu, Cinzia, Angela Peruzzu, Antonella Maria Fara, et al. "Immunohistochemistry as a Reliable Tool for the Diagnosis of Cystic Echinococcosis in Patients from Sardinia, Italy—A Confirmatory Study." Diseases 12, no. 5 (2024): 84. http://dx.doi.org/10.3390/diseases12050084.

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Cystic Echinococcosis (CE) is a zoonotic disease caused by the larval stage of the tapeworm Echinococcus granulosus sensu lato (s.l.). This study aims to investigate the use of two monoclonal antibodies (mAbEmG3 and mAbEm2G11) by immunohistochemistry (IHC) to confirm the diagnosis of CE in human patients, in particular in those cases in which other techniques fail to provide a correct or conclusive diagnosis. For this purpose, a survey on 13 patients was performed. These subjects were referred to Sardinian hospitals (Italy) from 2017 to 2022 and were suspected to be affected by CE. Our finding
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15

Xiao, Ning, Minoru Nakao, Jiamin Qiu, et al. "DUAL INFECTION OF ANIMAL HOSTS WITH DIFFERENT ECHINOCOCCUS SPECIES IN THE EASTERN QINGHAI-TIBET PLATEAU REGION OF CHINA." American journal of tropical medicine and hygiene 75, no. 2 (2006): 292–4. https://doi.org/10.5281/zenodo.15091990.

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The eastern Qinghai-Tibet plateau of China is a highly endemic region of echinococcosis where Echinococcus granulosus sensu stricto (sheep strain), Echinococcus multilocularis, and Echinococcus shiquicus are distributed sympatrically. We developed a polymerase chain reaction-based restriction fragment length polymorphism (PCR-RFLP) method for the identification of the three species in this region. The PCR-RFLP showed the dual infection of animals with different Echinococcus spp. The first case was a domestic dog concurrently infected with adults of E. granulosus and E. multilocularis. The seco
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16

Hamamcı, Berna, Günes Açıkgöz, Ülfet Çetinkaya, et al. "Molecular genotyping of Echinococcus granulosus sensu stricto from human Echinococcal cysts in Hatay, Türkiye." Experimental Parasitology 245 (February 2023): 108454. http://dx.doi.org/10.1016/j.exppara.2022.108454.

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17

Wang, Hui, Jun Li, Chuanshan Zhang, et al. "Echinococcus granulosus sensu stricto: silencing of thioredoxin peroxidase impairs the differentiation of protoscoleces into metacestodes." Parasite 25 (2018): 57. http://dx.doi.org/10.1051/parasite/2018055.

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Cystic echinococcosis (CE) is a cosmopolitan parasitic disease caused by infection with the larval stage of Echinococcus granulosus sensu lato. Thioredoxin peroxidase (TPx) may play an essential role in the antioxidant defence system of E. granulosus s.l. as neither catalase nor glutathione peroxidase activities have been detected in the parasite. However, it is not known whether TPx affects the survival and growth of E. granulosus s.l. during development. In this study, three fragments of siRNA specific for EgTPx (siRNA-1/2/3) were designed and transfected into protoscoleces of E. granulosus
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18

Monteiro, D. U., S. A. Botton, A. A. Tonin, et al. "Echinococcus canadensis (G7) and Echinococcus granulosus sensu stricto (G1) in swine of southern Brazil." Veterinary Parasitology 202, no. 3-4 (2014): 335–38. http://dx.doi.org/10.1016/j.vetpar.2014.01.023.

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19

Yanagida, Tetsuya, Tahereh Mohammadzadeh, Shaden Kamhawi, et al. "Genetic polymorphisms of Echinococcus granulosus sensu stricto in the Middle East." Parasitology International 61, no. 4 (2012): 599–603. http://dx.doi.org/10.1016/j.parint.2012.05.014.

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20

Šoba, Barbara, Špela Gašperšič, Darja Keše, and Tadeja Kotar. "Molecular Characterization of Echinococcus granulosus sensu lato from Humans in Slovenia." Pathogens 9, no. 7 (2020): 562. http://dx.doi.org/10.3390/pathogens9070562.

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The larval form of tapeworms of the Echinococcus granulosus sensu lato species cluster cause an important zoonotic infection, cystic echinococcosis (CE). Molecular characterization of the cluster’s isolates from different hosts greatly contributes to a better understanding of its transmission dynamics. To date, no genetic information is available on CE in Slovenia. In this work, we characterized isolates from human CE cases. Parasite samples from 18 patients were collected, together with the patients’ demographic and clinical data. Genomic DNA was analyzed by conventional PCR and sequencing at
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21

Maksimov, Pavlo, Hannes Bergmann, Marion Wassermann, et al. "Species Detection within the Echinococcus granulosus sensu lato Complex by Novel Probe-Based Real-Time PCRs." Pathogens 9, no. 10 (2020): 791. http://dx.doi.org/10.3390/pathogens9100791.

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Infections with eggs of Echinococcus granulosus sensu lato (s.l.) can cause cystic echinococcosis in intermediate host animals and humans. Upon ingestion of viable eggs, oncospheres hatch from the eggs and subsequently develop into fluid-filled larval cysts, most frequently in the liver or the lungs. The slowly growing cysts progressively interfere with organ function. The risk of infection is determined by the host range of the parasite, its pathogenicity and other epidemiologically relevant parameters, which differ significantly among the five species within the E. granulosus s.l. complex. I
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Kim, Hye-Jin, Tai-Soon Yong, Myeong Heon Shin, et al. "Phylogenetic Characteristics of Echinococcus granulosus Sensu Lato in Uzbekistan." Korean Journal of Parasitology 58, no. 2 (2020): 205–10. http://dx.doi.org/10.3347/kjp.2020.58.2.205.

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Echinococcosis occurs mainly in areas with heavy livestock farming, such as Central Asia, America, and Australia. <i>Echinococcus granulosus</i> sensu lato (s.l.) infection causes echinococcosis in intermediate hosts, such as sheep, cattle, goats, camels, and horses. Numerous cases of echinococcosis occur in Uzbekistan as stock farming is a primary industry. Epidemiological and genetic studies of <i>E. granulosus</i> s.l. are very important for mitigating its impact on public health and the economy; however, there are no such studies on <i>E. granulosus</i>
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23

Utuk, A. E., and S. Simsek. "Molecular characterization of the horse isolate of Echinococcus granulosus in Turkey." Journal of Helminthology 87, no. 3 (2012): 305–8. http://dx.doi.org/10.1017/s0022149x12000363.

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AbstractCystic echinococcosis is one of the most important helminthozoonoses, affecting various species of intermediate hosts and humans. In this report, we present Echinococcus granulosus infection in a horse and its molecular characterization. Polymerase chain reaction (PCR) amplification of mitochondrial 12S rRNA (mt-12S rRNA) and partial sequencing of mitochondrial cytochrome c oxidase subunit 1 (mt-CO1) genes were performed. According to the mt-12S rRNA-PCR result, the horse isolate was grouped with E. granulosus sensu stricto (G1–G3) and the partial mt-CO1 sequence corresponded to the G1
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Šnábel, Viliam, Tetiana Kuzmina, Serena Cavallero, et al. "A molecular survey of Echinococcus granulosus sensu lato in central-eastern Europe." Open Life Sciences 11, no. 1 (2016): 524–32. http://dx.doi.org/10.1515/biol-2016-0066.

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AbstractCentral-eastern Europe is an endemic region for cystic echinococcosis where multiple species of intermediate hosts are commonly infected with Echinococcus granulosus sensu lato tapeworms of major medical and veterinary importance. Investigations of the genetic variation of 25 Echinococcus isolates from five countries (Slovakia, Romania, Ukraine, Hungary, Poland) were undertaken using three mitochondrial DNA markers. The 18 isolates from pigs derived from Slovakia and Ukraine and the four human isolates from Slovakia, Poland and Ukraine were identified as E. canadensis G 7, whereas the
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Balbinotti, Helier, Guilherme B. Santos, Jeferson Badaraco, et al. "Echinococcus ortleppi (G5) and Echinococcus granulosus sensu stricto (G1) loads in cattle from Southern Brazil." Veterinary Parasitology 188, no. 3-4 (2012): 255–60. http://dx.doi.org/10.1016/j.vetpar.2012.04.007.

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26

OGUZ, B., O. SELCIN, MS DEGER, K. BICEK, and N. OZDAL. "A Case Report of Echinococcus granulosus sensu stricto (G1) in a Domestic Cat in Turkey." Journal of the Hellenic Veterinary Medical Society 72, no. 4 (2022): 3537. http://dx.doi.org/10.12681/jhvms.29408.

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Echinococcus granulosus sensu lato is a zoonotic helminth with a life cycle that include of definitive hosts (dogs and wild carnivores) and intermediate hosts (usually the even-toed ungulates, Artiodactyla). Intermediate hosts become infected by ingesting the parasite eggs in contaminated food and water. Accidental intermediate hosts acquire infection in a similar way as other intermediate hosts. A two-year-old female cat was presented to the Van (Turkey) Animal Care and Rehabilitation Center with abdominal tension. Multiple intraperitoneal vesicles, which were found to be E. granulosus (s.1.)
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Moussa, Daouia, Kheira Senouci, Nori Midoun, et al. "Genetic diversity of Echinococcus granulosus sensu stricto infecting humans in western Algeria." Parasitology Research 120, no. 9 (2021): 3195–202. http://dx.doi.org/10.1007/s00436-021-07223-7.

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28

Umhang, Gérald, Frédéric Grenouillet, Vanessa Bastid, et al. "Investigating the genetic diversity of Echinococcus granulosus sensu stricto with new microsatellites." Parasitology Research 117, no. 9 (2018): 2743–55. http://dx.doi.org/10.1007/s00436-018-5963-y.

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29

Bonelli, Piero, Gabriella Masu, Silvia Dei Giudici, et al. "Cystic echinococcosis in a domestic cat (Felis catus) in Italy." Parasite 25 (2018): 25. http://dx.doi.org/10.1051/parasite/2018027.

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Echinococcus granulosus sensu lato is a zoonotic agent with a life cycle consisting of definitive hosts (dogs and wild carnivores), and intermediate hosts (usually ungulates). Other animals and humans may accidentally ingest eggs and contract cystic echinococcosis, acting as aberrant hosts. A 3-year-old neutered female cat was brought to a veterinary practice in Sassari (Italy) with abdominal distension. Ultrasound showed multiple intraperitoneal vesicles, which on laparotomy were found to be metacestodes of E. granulosus. Videos of the extraction of cysts are provided. Phylogenetic analysis b
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Al-Hizab, Fahad A., Nouh S. Mohamed, Marion Wassermann, et al. "Three species of Echinococcus granulosus sensu lato infect camels on the Arabian Peninsula." Parasitology Research 120, no. 6 (2021): 2077–86. http://dx.doi.org/10.1007/s00436-021-07156-1.

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AbstractWe report on the genetic identity of 36 Echinococcus cysts that were collected during a recent slaughterhouse survey of 810 locally bred camels (dromedaries) in the Eastern Province of the Kingdom of Saudi Arabia. Analysis of a partial nad1 gene sequence showed that the majority (n = 29) belonged to E. granulosus sensu stricto, four to E. canadensis G6/7, and three to E. ortleppi. Eight of the 29 E. granulosus s.s. cysts contained protoscoleces; all other cysts were calcified and non-viable. This is the first report of the presence E. ortleppi from the Arabian Peninsula, a parasite tha
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Chen, Fan, Lei Liu, Qili He, et al. "A multiplex PCR for the identification of Echinococcus multilocularis, E. granulosus sensu stricto and E. canadensis that infect human." Parasitology 146, no. 12 (2019): 1595–601. http://dx.doi.org/10.1017/s0031182019000921.

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AbstractEchinococcus granulosus sensu stricto (s.s.), Echinococcus multilocularis and Echinococcus canadensis are the common causes of human echinococcosis in China. An accurate species identification tool for human echinococcosis is needed as the treatments and prognosis are different among species. The present work demonstrates a method for the simultaneous detection of these three Echinococcus species based on multiplex polymerase chain reaction (mPCR). Specific primers of this mPCR were designed based on the mitochondrial genes and determined by extensive tests. The method can successfully
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Kinkar, Liina, Teivi Laurimäe, Ibrahim Balkaya, et al. "Genetic diversity and phylogeography of the elusive, but epidemiologically important Echinococcus granulosus sensu stricto genotype G3." Parasitology 145, no. 12 (2018): 1613–22. http://dx.doi.org/10.1017/s0031182018000549.

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AbstractCystic echinococcosis (CE) is a severe parasitic disease caused by the species complex Echinococcus granulosus sensu lato. Human infections are most commonly associated with E. granulosus sensu stricto (s.s.), comprising genotypes G1 and G3. The objective of the current study was to provide first insight into the genetic diversity and phylogeography of genotype G3. Despite the epidemiological importance of the genotype, it has remained poorly explored due to the ambiguity in the definition of the genotype. However, it was recently demonstrated that long sequences of mitochondrial DNA (
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33

Nakao, M., T. Li, X. Han, et al. "Genetic polymorphisms of Echinococcus tapeworms in China as determined by mitochondrial and nuclear DNA sequences." International journal for parasitology 40, no. 3 (2010): 379–85. https://doi.org/10.1016/j.ijpara.2009.09.006.

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The genetic polymorphisms of Echinococcus spp. in the eastern Tibetan Plateau and the Xinjiang Uyghur Autonomous Region were evaluated by DNA sequencing analyses of genes for mitochondrial cytochrome c oxidase subunit 1 (cox1) and nuclear elongation factor-1 alpha (ef1a). We collected 68 isolates of Echinococcus granulosus sensu stricto (s.s.) from Xinjiang and 113 isolates of E. granulosus s. s., 49 isolates of Echinococcus multilocularis and 34 isolates of Echinococcus shiquicus from the Tibetan Plateau. The results of molecular identification by mitochondrial and nuclear markers were identi
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34

Santucciu, Cinzia, Piero Bonelli, Angela Peruzzu, et al. "Cystic Echinococcosis: Clinical, Immunological, and Biomolecular Evaluation of Patients from Sardinia (Italy)." Pathogens 9, no. 11 (2020): 907. http://dx.doi.org/10.3390/pathogens9110907.

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Cystic echinococcosis (CE), a zoonotic disease caused by the larval stage of the tapeworm Echinococcus granulosus sensu lato (s.l.), is a worldwide public health problem. Echinococcus granulosus sensu stricto (s.s.), associated with G1 and G3 genotypes, is endemic with high prevalence in the Mediterranean basin. The parasite’s life cycle comprises definitive hosts (canids) and intermediate hosts (ruminants) and can occasionally involve humans. The main aim of this research was to confirm the diagnosis of 13 patients suspected of CE who presented different complications and needed the surgical
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35

Santucciu, Cinzia. "Cystic Echinococcosis: Clinical, Immunological, and Biomolecular Evaluation of Patients from Sardinia (Italy)." Pathogens- MDPI 9, Special Issue : Echinococcus (2020): 907. https://doi.org/10.3390/pathogens9110907.

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Abstract: Cystic echinococcosis (CE), a zoonotic disease caused by the larval stage of the tapeworm Echinococcus granulosus sensu lato (s.l.), is a worldwide public health problem. Echinococcus granulosus sensu stricto (s.s.), associated with G1 and G3 genotypes, is endemic with high prevalence in the Mediterranean basin. The parasite’s life cycle comprises definitive hosts (canids) and intermediate hosts (ruminants) and can occasionally involve humans. The main aim of this research was to confirm the diagnosis of 13 patients suspected of CE who presented different complications and need
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Zait, Houria, Mokhtaria Kouidri, Florence Elisabeth Grenouillet, et al. "Molecular characterization of Echinococcus granulosus sensu stricto and Echinococcus canadensis in humans and livestock from Algeria." Parasitology Research 115, no. 6 (2016): 2423–31. http://dx.doi.org/10.1007/s00436-016-4994-5.

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Boufana, Belgees, Wai San Lett, Samia Lahmar, et al. "Echinococcus equinus and Echinococcus granulosus sensu stricto from the United Kingdom: genetic diversity and haplotypic variation." International Journal for Parasitology 45, no. 2-3 (2015): 161–66. http://dx.doi.org/10.1016/j.ijpara.2014.10.005.

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38

Ali, Viterman, Eddy Martinez, Pamela Duran, Erick Villena, Peter Deplazes, and Cristian A. Alvarez Rojas. "Past and present of cystic echinococcosis in Bolivia." PLOS Neglected Tropical Diseases 15, no. 6 (2021): e0009426. http://dx.doi.org/10.1371/journal.pntd.0009426.

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Viable eggs of the canine intestinal tapeworm Echinococcus granulosus sensu lato (s.l.) infect various intermediate hosts causing cystic echinococcosis (CE). Furthermore, CE represents a serious zoonosis causing a significant global burden of disease. CE is highly endemic in South America, including Argentina, Brazil, Chile, Uruguay, and Peru. For Bolivia, no official data concerning the incidence in humans or the number of livestock and dogs infected are available. However, it is well known that CE occurs in Bolivia. We aim here to fill the gap in the current knowledge of the epidemiological
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Albani, C. M., J. Borgo, J. Fabbri, et al. "Anthelmintic activity of Stevia multiaristata extract against Echinococcus granulosus sensu stricto." Parasitology 149, no. 4 (2021): 519–28. http://dx.doi.org/10.1017/s0031182021002109.

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AbstractCystic echinococcosis is a zoonotic disease caused by the larval stage of the parasite Echinococcus granulosus sensu lato. The available anti-parasitic treatment is mostly limited to a continuous administration of albendazole. However, due to its numerous side-effects and efficacy of around 50%, there is a need to find new drugs to improve the treatment for this disease. In the current study, the in vitro and in vivo efficacy of a Stevia multiaristata extract against E. granulosus sensu stricto (s.s.) was demonstrated. Stevia multiaristata extract (100 and 50 μg mL−1) caused a quick vi
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Örsten, Serra, Türkmen Çiftçi, Aynur Azizova, et al. "Investigation of the relationship between CE cyst characteristics and genetic diversity of Echinococcus granulosus sensu lato in humans from Turkey." Parasitology 147, no. 14 (2020): 1712–17. http://dx.doi.org/10.1017/s0031182020001535.

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AbstractCystic echinococcosis (CE) is one of the most common zoonotic diseases worldwide, particularly in rural areas. This study aimed at the identification of the genotype/species belonging to Echinococcus granulosus sensu lato (s.l.) specimens in retrieved percutaneously from the human host and to investigate their relationship with cyst characteristics. The genetic identification of cyst material was performed by mt-CO1 gene polymerase chain reaction, and confirmed via sequencing. A total of 110 CE cysts were identified as E. granulosus s.l. In detail, 104 belonged to E. granulosus sensu s
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KONYAEV, SERGEY V., TETSUYA YANAGIDA, MINORU NAKAO, et al. "Genetic diversity of Echinococcus spp. in Russia." Parasitology 140, no. 13 (2013): 1637–47. http://dx.doi.org/10.1017/s0031182013001340.

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SUMMARYIn Russia, both alveolar and cystic echinococcoses are endemic. This study aimed to identify the aetiological agents of the diseases and to investigate the distribution of each Echinococcus species in Russia. A total of 75 Echinococcus specimens were collected from 14 host species from 2010 to 2012. Based on the mitochondrial DNA sequences, they were identified as Echinococcus granulosus sensu stricto (s.s.), E. canadensis and E. multilocularis. E. granulosus s.s. was confirmed in the European Russia and the Altai region. Three genotypes, G6, G8 and G10 of E. canadensis were detected in
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Mehmood, Sarfraz, Sami Simsek, Figen Celik, Harun Kaya Kesik, Seyma Gunyakti Kilinc, and Haroon Ahmed. "Molecular survey on cattle and sheep hydatidosis and first detection of Echinococcus canadensis (G6/G7) in sheep in Turkey." Parasitology 147, no. 9 (2020): 1055–62. http://dx.doi.org/10.1017/s0031182020000785.

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AbstractLarval stage of genus Echinococcus is the causing agent for the zoonotic infection which is life threatening known as Echinococcosis. The purpose of this study was the identification, molecular analysis and characterization of Echinococcus spp. in sheep and cattle. The sampling was done from slaughterhouse of Elazig, Turkey. A total of 85 isolates (sheep, n = 19 and cattle, n = 66) have been collected after slaughtering. Following the gDNA isolation and PCR products of mt-CO1 gene (446 bp) of all the samples were sequenced. Out of 85 isolates, 84 were recognized as Echinococcus granulo
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Crotti, Silvia, Leonardo Brustenga, Deborah Cruciani, et al. "Molecular Screening of Echinococcus spp. and Other Cestodes in Wild Carnivores from Central Italy." Veterinary Sciences 10, no. 5 (2023): 318. http://dx.doi.org/10.3390/vetsci10050318.

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Tapeworm infections are among the most relevant parasitic diseases in humans and animals. Tapeworms from the Genus Echinococcus are particularly important as they can cause cystic or alveolar echinococcosis. A molecular screening was performed on 279 fecal samples collected from carcasses of wild carnivores from Central Italy using PCR targeting diagnostic fragments of nad1, rrnS, and nad5 genes. Samples positive for either Taenia spp. or Echinococcus granulosus were sequenced to taxonomically identify the parasitic DNA. Of the 279 samples, 134 (48.0%) gave positive results in the multiplex PC
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Guo, Baoping, Zhuangzhi Zhang, Xueting Zheng, et al. "Prevalence and Molecular Characterization of Echinococcus granulosus Sensu Stricto in Northern Xinjiang, China." Korean Journal of Parasitology 57, no. 2 (2019): 153–59. http://dx.doi.org/10.3347/kjp.2019.57.1.153.

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Guo, Baoping, Zhuangzhi Zhang, Xueting Zheng, et al. "Prevalence and Molecular Characterization of Echinococcus granulosus Sensu Stricto in Northern Xinjiang, China." Korean Journal of Parasitology 57, no. 2 (2019): 153–59. http://dx.doi.org/10.3347/kjp.2019.57.2.153.

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Omer, Rihab Ali, Arwid Daugschies, Sandra Gawlowska, et al. "First detection of Echinococcus granulosus sensu stricto (G1) in dogs in central Sudan." Parasitology Research 117, no. 5 (2018): 1657–61. http://dx.doi.org/10.1007/s00436-018-5851-5.

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Hidalgo, Christian, Caroll Stoore, Ismael Pereira, Rodolfo Paredes, and Cristian A. Alvarez Rojas. "Multiple haplotypes of Echinococcus granulosus sensu stricto in single naturally infected intermediate hosts." Parasitology Research 119, no. 2 (2019): 763–70. http://dx.doi.org/10.1007/s00436-019-06578-2.

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Wassermann, Marion, Daniel Woldeyes, Banchwosen Mechal Gerbi, et al. "A novel zoonotic genotype related to Echinococcus granulosus sensu stricto from southern Ethiopia." International Journal for Parasitology 46, no. 10 (2016): 663–68. http://dx.doi.org/10.1016/j.ijpara.2016.04.005.

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Bia, Mohammed Mebarek, Seongjun Choe, Barakaeli Abdieli Ndosi, et al. "Genotypes of Echinococcus Species from Cattle in Tanzania." Korean Journal of Parasitology 59, no. 5 (2021): 457–64. http://dx.doi.org/10.3347/kjp.2021.59.5.457.

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Cystic echinococcosis is a zoonotic parasitic disease caused by Echinococcus species. Tanzania is one of the endemic countries with cystic echinococcosis. This study focussed on identifying genotypes of Echinococcus spp. in Tanzania. We collected 7 cysts from cattle in Mwanza municipal (n=4) and Loliondo district (n=3). The cysts from Mwanza were all E. ortleppi and fertile. In contrast, the cysts from Loliondo were all E. granulosus sensu stricto and sterile. Two from the 4 cysts were a new haplotype of E. ortleppi (G5). These results can improve the preventive and control programs for humans
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Kaethner, Marc, Matías Preza, Tobias Kaempfer, et al. "Establishment and application of unbiased in vitro drug screening assays for the identification of compounds against Echinococcus granulosus sensu stricto." PLOS Neglected Tropical Diseases 17, no. 8 (2023): e0011343. http://dx.doi.org/10.1371/journal.pntd.0011343.

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Echinococcus multilocularis and E. granulosus s.l. are the causative agents of alveolar and cystic echinococcosis, respectively. Drug treatment options for these severe and neglected diseases are limited to benzimidazoles, which are not always efficacious, and adverse side effects are reported. Thus, novel and improved treatments are needed. In this study, the previously established platform for E. multilocularis in vitro drug assessment was adapted to E. granulosus s.s. In a first step, in vitro culture protocols for E. granulosus s.s. were established. This resulted in the generation of larg
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