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Journal articles on the topic 'Echinococcus multilocularis'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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1

Dobrovolskis, Paulius. "ECHINOCOCCUS MULTILOCULARIS SUKELTOS KEPENŲ INFEKCIJOS CHIRURGINIS GYDYMAS." Health Sciences 32, no. 4 (2022): 117–19. http://dx.doi.org/10.35988/sm-hs.2022.159.

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Tikslas. Apžvelgti galimas Echinococcus multilocularis kepenų židinių chirurginio gydymo taktikas ir jų indikacijas, aprašytas mokslinėje literatūroje. Įvertinti Echinococcus multilocularis sukeltos kepenų infekcijos gydymo būdą, taikant kepenų rezekciją ir vartų venos ligaciją. Medžiaga ir metodai. Apžvelgta mokslinė literatūra, aprašanti Echinococcus multilocularis sukeltos kepenų infekcijos chirurginio gydymo ypatumus. Mokslinė literatūros paieška atlikta Pubmed duomenų bazėje. Rezultatai. Išanalizuota 20 mokslinės literatūros straipsnių (iš jų 6 metaanalizės), aprašančių Echinococcus

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2

Craig, Philip. "Echinococcus multilocularis." Current Opinion in Infectious Diseases 16, no. 5 (2003): 437–44. http://dx.doi.org/10.1097/00001432-200310000-00010.

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3

Casulli, Adriano, Thomas F. E. Barth, and Francesca Tamarozzi. "Echinococcus multilocularis." Trends in Parasitology 35, no. 9 (2019): 738–39. http://dx.doi.org/10.1016/j.pt.2019.05.005.

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4

Piarroux, Renaud. "Echinococcus multilocularis." EMC - Biologie Médicale 1, no. 1 (2006): 1–4. http://dx.doi.org/10.1016/s2211-9698(06)76269-0.

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5

Wang, Qian, Yong-Fu Xiao, Dominique A. Vuitton, et al. "Impact of overgrazing on the transmission of Echinococcus multilocularis in Tibetan pastoral communities of Sichuan Province, China." Chinese medical journal 120, no. 3 (2007): 237–42. https://doi.org/10.5281/zenodo.15092018.

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Overgrazing was assumed to increase the population density of small mammals that are the intermediate hosts of Echinococcus multilocularis, the pathogen of alveolar echinococcosis in the Qinghai Tibet Plateau. This research tested the hypothesis that overgrazing might promote Echinococcus multilocularis transmission through increasing populations of small mammal, intermediate hosts in Tibetan pastoral communities. Grazing practices, small mammal indices and dog Echinococcus multilocularis infection data were collected to analyze the relation between overgrazing and Echinococcus multilocularis

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6

Williams, D. F., G. A. Williams, J. G. Caya, R. P. Werner, and T. J. Harrison. "Intraocular Echinococcus multilocularis." Archives of Ophthalmology 105, no. 8 (1987): 1106–9. http://dx.doi.org/10.1001/archopht.1987.01060080108038.

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7

Zewude, Rahel T., Antoine Corbeil, Scott Fung, Carol-Anne Moulton, and Isaac I. Bogoch. "Alveolar Echinococcus in a 70-year-old man in Ontario." Journal of the Association of Medical Microbiology and Infectious Disease Canada 8, no. 4 (2024): 336–42. http://dx.doi.org/10.3138/jammi-2023-0012.

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Background: Alveolar echinococcus, caused by the tapeworm Echinococcus multilocularis, mimics hepatic malignancy, and carries a mortality rate exceeding 90% in untreated patients. Methods: Diagnosis of E. multilocularis infection is established through clinical, radiographic, and microbiological assessments. Currently available laboratory diagnostics in Ontario are fresh tissue microscopy and histopathology. However, genus-specific Echinococcus enzyme-linked immunosorbent assay (ELISA) serology as well as confirmatory testing with species-specific serology and E. multilocularis polymerase chai

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8

Schurer, Janna M., Karen M. Gesy, Brett T. Elkin, and Emily J. Jenkins. "Echinococcus multilocularis and Echinococcus canadensis in wolves from western Canada." Parasitology 141, no. 2 (2014): 159–63. https://doi.org/10.1017/S0031182013001716.

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Echinococcus species are important parasites of wildlife, domestic animals and people worldwide; however, little is known about the prevalence, intensity and genetic diversity of Echinococcus tapeworms in Canadian wildlife. Echinococcus tapeworms were harvested from the intestines of 42% of 93 wolves (Canis lupus) from five sampling regions in the Northwest Territories, Manitoba and Saskatchewan, and visually identified to genus level by microscopic examination. Genetic characterization was successful for tapeworms from 30 wolves, and identified both Echinococcus canadensis and Echinococcus mu

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9

Avcioglu, Hamza, Esin Guven, Ibrahim Balkaya, Ridvan Kirman, Mohammed Mebarek Bia, and Hatice Gulbeyen. "First Molecular Characterization of Echinococcus multilocularis in Turkey." Vector borne and zoonotic diseases 16, no. 9 (2016): 627–29. https://doi.org/10.1089/vbz.2016.1983.

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This study aimed to find out the occurrence of Echinococcus multilocularis in foxes in Erzurum province, the highest endemic region for human alveolar echinococcosis in Turkey. The sedimentation and counting technique was used to reveal adult Echinococcus spp. in the intestines of foxes. One out of the 10 foxes was infected with E. multilocularis. The adult worms were analyzed morphologically and molecularly and were confirmed to be E. multilocularis by species-specific PCR. Pairwise comparisons between the 12S rRNA sequences of the E. multilocularis isolate from Erzurum and other E. multilocu

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10

Tang, Chong-Ti, Yan-Hai Wang, Wen-Feng Peng, Liang Tang, and Dong Chen. "ALVEOLAR ECHINOCOCCUS SPECIES FROM VULPES CORSAC IN HULUNBEIER, INNER MONGOLIA, CHINA, AND DIFFERENTIAL DEVELOPMENT OF THE METACESTODES IN EXPERIMENTAL RODENTS." Journal of parasitology 92, no. 4 (2006): 719–24. https://doi.org/10.1645/GE-3526.1.

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Adults of alveolar Echinococcus species with different uterine structures were collected from Vulpes corsac in the Hulunbeier Pasture of Northeastern China in 2001. They were Echinococcus multilocularis Leuckart, 1863 (type No. 3, similar to E. m. multilocularis), with vaselike uterus; Echinococcus cf. sibiricensis Rausch et Schiller, 1954 (type No. 1), with pyriform uterus; and Echinococcus sp. (type No. 2) with spherical uterus at segment top. The metacestode development in rodents also differed among those 3 parasites. In the case of E. multilocularis (type No. 3), many germinal cells grew

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11

Xiao, Ning, Minoru Nakao, Jiamin Qiu, et al. "DUAL INFECTION OF ANIMAL HOSTS WITH DIFFERENT ECHINOCOCCUS SPECIES IN THE EASTERN QINGHAI-TIBET PLATEAU REGION OF CHINA." American journal of tropical medicine and hygiene 75, no. 2 (2006): 292–4. https://doi.org/10.5281/zenodo.15091990.

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The eastern Qinghai-Tibet plateau of China is a highly endemic region of echinococcosis where Echinococcus granulosus sensu stricto (sheep strain), Echinococcus multilocularis, and Echinococcus shiquicus are distributed sympatrically. We developed a polymerase chain reaction-based restriction fragment length polymorphism (PCR-RFLP) method for the identification of the three species in this region. The PCR-RFLP showed the dual infection of animals with different Echinococcus spp. The first case was a domestic dog concurrently infected with adults of E. granulosus and E. multilocularis. The seco

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12

SCHURER, JANNA M., KAREN M. GESY, BRETT T. ELKIN, and EMILY J. JENKINS. "Echinococcus multilocularis and Echinococcus canadensis in wolves from western Canada." Parasitology 141, no. 2 (2013): 159–63. http://dx.doi.org/10.1017/s0031182013001716.

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SUMMARYEchinococcus species are important parasites of wildlife, domestic animals and people worldwide; however, little is known about the prevalence, intensity and genetic diversity of Echinococcus tapeworms in Canadian wildlife. Echinococcus tapeworms were harvested from the intestines of 42% of 93 wolves (Canis lupus) from five sampling regions in the Northwest Territories, Manitoba and Saskatchewan, and visually identified to genus level by microscopic examination. Genetic characterization was successful for tapeworms from 30 wolves, and identified both Echinococcus canadensis and Echinoco

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13

Beiromvand, M., L. Akhlaghi, Massom SH Fattahi, et al. "Detection of Echinococcus multilocularis in Carnivores in Razavi Khorasan Province, Iran Using Mitochondrial DNA." PLoS neglected tropical diseases 5, no. 11 (2011): e1379. https://doi.org/10.1371/journal.pntd.0001379.

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Echinococcus multilocularis is the source of alveolar echinococcosis, a potentially fatal zoonotic disease. This investigation assessed the presence of E. multilocularis infection in definitive hosts in the Chenaran region of Razavi Khorasan Province, northeastern Iran.", "Fecal samples from 77 domestic and stray dogs and 14 wild carnivores were examined using the flotation/sieving method followed by multiplex PCR of mitochondrial genes. The intestinal scraping technique (IST) and the sedimentation and counting technique (SCT) revealed adult Echinococcus in the intestines of five of 10 jackals

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14

ITO, AKIRA, GANTIGMAA CHULUUNBAATAR, TETSUYA YANAGIDA, et al. "Echinococcus species from red foxes, corsac foxes, and wolves in Mongolia." Parasitology 140, no. 13 (2013): 1648–54. http://dx.doi.org/10.1017/s0031182013001030.

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SUMMARYThe small intestines of 420 wild canids (111 corsac foxes, 191 red foxes and 118 wolves) from Mongolia, were examined for adult worms of the genus Echinococcus. The Mongolian genotype of Echinococcus multilocularis was found in fifteen red foxes and four wolves, whereas two genotypes (G6/7 and G10) of Echinococcus canadensis were found in two and three wolves, respectively. No adult Echinococcus worms were found in the corsac foxes examined. The genotypes of E. multilocularis and E. canadensis are discussed in terms of host specificity and distribution in Mongolia. The importance of wol

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15

Chen, Lujuan, Zhe Cheng, Siqi Xian, et al. "Immunization with EmCRT-Induced Protective Immunity against Echinococcus multilocularis Infection in BALB/c Mice." Tropical Medicine and Infectious Disease 7, no. 10 (2022): 279. http://dx.doi.org/10.3390/tropicalmed7100279.

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Alveolar echinococcosis (AE) is a severe parasitic zoonosis caused by the larval stage of Echinococcus multilocularis. The identification of the antigens eliciting acquired immunity during infection is important for vaccine development against Echinococcus infection. Here, we identified that E. multilocularis calreticulin (EmCRT), a ubiquitous protein with a Ca2+-binding ability, could be recognized by the sera of mice infected with E. multilocularis. The native EmCRT was expressed on the surface of E. multilocularis larvae as well as in the secreted products of metacestode vesicles and protos

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16

Ma, J., H. Wang, G. Lin, et al. "Molecular identification of Echinococcus species from eastern and southern Qinghai, China, based on the mitochondrial cox1 gene." Parasitology research 111, no. 1 (2012): 179–84. https://doi.org/10.1007/s00436-012-2815-z.

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The Qinghai-Tibetan Plateau (QTP, in western China), which is the largest and highest plateau on Earth, is a highly epidemic region for Echinococcus spp. We collected 70 Echinococcus samples from humans, dogs, sheep, yaks, plateau pikas, and voles in eastern and southern Qinghai and genotyped them using the mitochondrial DNA marker cytochrome oxidase subunit I gene and maximum parsimony and Bayesian reconstruction methods. Based on the 792-bp sequence matrix, we recorded 124 variable sites, of which, 115 were parsimony-informative. Thirty-four haplotypes (H1-H34) were detected, of which H1-H15

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17

Boucher, JM, R. Hanosset, D. Augot, et al. "Detection of Echinococcus multilocularis in wild boars in France using PCR techniques against larval form." Veterinary parasitology 129, no. 4-Mar (2005): 259–66. https://doi.org/10.1016/j.vetpar.2004.09.021.

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Recently, new data have been collected on the distribution and ecology of Echinococcus multilocularis in European countries. Different ungulates species such as pig, goat, sheep, cattle and horse are known to host incomplete development of larval E. multilocularis. We report a case of E. multilocularis portage in two wild boars from a high endemic area in France (Department of Jura). Histological examination was performed and the DNA was isolated from hepatic lesions then amplified by using three PCR methods in two distinct institutes. Molecular characterisation of PCR products revealed 99% nu

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18

Gao, Haijun, Zhuoma Bianba, Xiaojin Mo, et al. "Receptor Tyrosine Kinase Signaling Involves Echinococcus–Host Intercommunication: A Potential Therapeutic Target in Hepatic Echinococcosis." Tropical Medicine and Infectious Disease 9, no. 8 (2024): 175. http://dx.doi.org/10.3390/tropicalmed9080175.

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Echinococcosis, one of the most serious and life-threatening parasitic forms of zoonosis worldwide, is caused by the larvae of Echinococcus granulosus (E. granulosus) and Echinococcus multilocularis (E. multilocularis). Various drugs are being applied clinically to treat zoonosis; however, their therapeutic efficacy remains a great challenge, especially with albendazole as the preferred drug of choice. Receptor tyrosine kinase (RTK) signaling controls normal cellular proliferation, differentiation, and metabolism in humans and mammals, which are intermediate hosts of E. granulosus and E. multi

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19

Gauci, Charles, Michael Merli, Volker Muller, et al. "Molecular Cloning of a Vaccine Antigen against Infection with the Larval Stage of Echinococcus multilocularis." Infection and Immunity 70, no. 7 (2002): 3969–72. http://dx.doi.org/10.1128/iai.70.7.3969-3972.2002.

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ABSTRACT Alveolar and cystic hydatidosis are caused by infection with the larval stages of Echinococcus multilocularis and Echinococcus granulosus, respectively. A host-protective antigen has been identified in E. granulosus. Here we identify the presence of a closely related protein in E. multilocularis, characterize and express a cDNA encoding the antigen (designated EM95), determine the structure of the em95 gene, and demonstrate that the EM95 recombinant protein can be used to induce significant levels of protection against challenge infection with E. multilocularis eggs in mice.

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20

Lavallée-Bourget, Ève-Marie, Christopher Fernandez-Prada, Ariane Massé, Patricia Turgeon, and Julie Arsenault. "Prevalence and geographic distribution of Echinococcus genus in wild canids in southern Québec, Canada." PLOS ONE 19, no. 7 (2024): e0306600. http://dx.doi.org/10.1371/journal.pone.0306600.

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Echinococcus spp. is an emerging zoonotic parasite of high concern. In Canada, an increase in the number of human and animal cases diagnosed has been reported, but information regarding the parasite’s distribution in wildlife reservoir remains limited. A cross-sectional study was conducted to estimate the prevalence of wild canids infected with Echinococcus spp. and Echinococcus multilocularis in areas surrounding populated zones in Québec (Canada); to investigate the presence of areas at higher risk of infection; to evaluate potential risk factors of the infection; and as a secondary objectiv

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21

Wright, Ian. "Echinococcus multilocularis: a political zoonosis." Companion Animal 18, no. 8 (2013): 368–71. http://dx.doi.org/10.12968/coan.2013.18.8.368.

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22

PERSAT, F., J. BOUHOURS, A. PETAVY, and M. MOJON. "Gangliosides of Echinococcus multilocularis metacestodes." Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1225, no. 3 (1994): 297–303. http://dx.doi.org/10.1016/0925-4439(94)90010-8.

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23

Persat, Florence, Jean-François Bouhours, Madeleine Mojon, and Anne-Françoise Petavy. "Glycosphingolipids of Echinococcus multilocularis metacestodes." Molecular and Biochemical Parasitology 38, no. 1 (1990): 97–103. http://dx.doi.org/10.1016/0166-6851(90)90209-5.

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24

Suchail, S., M. E. Sarciron, and A. F. Petavy. "Purine metabolism in Echinococcus multilocularis." Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 120, no. 4 (1998): 633–37. http://dx.doi.org/10.1016/s0305-0491(98)10054-8.

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Persat, F., M. Mojon, and A. F. Petavy. "Lipids of Echinococcus multilocularis metacestodes." Comparative Biochemistry and Physiology Part B: Comparative Biochemistry 91, no. 1 (1988): 133–36. http://dx.doi.org/10.1016/0305-0491(88)90124-1.

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Sréter, Tamás, Zoltán Széll, Zsuzsanna Sréter-Lancz, and István Varga. "Echinococcus multilocularis in Northern Hungary." Emerging infectious diseases 10, no. 7 (2004): 1344–46. https://doi.org/10.3201/eid1007.031027.

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Of 150 foxes examined, 19 animals from four counties (Gyor-Sopron, Komárom-Esztergom, Pest, and Nógrád) harbored 2, 3, 4, 6, 7, 14, 22, 31, 51, 54, 114, 130, 200, 250, 300, 400, 800, and 1,300, and 5,500 mature worms of Echinococcus. On the basis of the most important morphometric guidelines and the results of the species-specific polymerase chain reaction (PCR) assay, the parasites were identified as E. multilocularis. The examined foxes were found from 5 to 70 km from the known endemic areas of the Slovak Republic, Austria.

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Manfredi, MT, A. Casulli, Rosa G. La, et al. "Echinococcus multilocularis in north Italy." Parassitologia 48, no. 2-Jan (2006): 43–46. https://doi.org/10.5281/zenodo.15092002.

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Alveolar echinococcosis is a zoonotic infection caused by the metacestode of the tapeworm Echinococcus multilocularis. Fox populations living in the Alpine regions of Italy had been considered free from this parasite until 2002, when two infected foxes were detected in Bolzano province (Trentino Alto Adige region) near Austrian border. A modified nested PCR analysis was used to detect E. multilocularis DNA in faecal samples belonging to red fox populations from five Italian regions. A total of 522 faecal samples were analysed from foxes shot in Valle d'Aosta (N = 65), Liguria (N = 44), Lombard

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Budke, Christine M., Maiza Campos-Ponce, Wang Qian, and Paul R. Torgerson. "A Canine Purgation Study And Risk Factor Analysis For Echinococcosis In A High Endemic Region Of The Tibetan Plateau." Veterinary parasitology 127, no. 1 (2005): 43–49. https://doi.org/10.1016/j.vetpar.2004.08.024.

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The Tibetan plateau of western China has been shown to have a very high prevalence of human cystic echinococcosis (CE) caused by Echinococcus granulosus and human alveolar echinococcosis (AE) caused by Echinococcus multilocularis. The domestic dog is suspected to be the primary definitive host for the transmission of both E. granulosus and E. multilocularis to humans in this locality. A purgation study of 371 dogs in Shiqu County, Sichuan Province during 2002-2003 resulted in an E. multilocularis prevalence of 12% and an E. granulosus prevalence of 8%. These crude prevalences were then adjuste

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Spicher, Martin, Carole Roethlisberger, Catharina Lany, et al. "In Vitro and In Vivo Treatments of Echinococcus Protoscoleces and Metacestodes with Artemisinin and Artemisinin Derivatives." Antimicrobial Agents and Chemotherapy 52, no. 9 (2008): 3447–50. http://dx.doi.org/10.1128/aac.00553-08.

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ABSTRACT In vitro treatment of Echinococcus multilocularis and Echinococcus granulosus larval stages with the antimalarials dihydroartemisinin and artesunate (10 to 40 μM) exhibited promising results, while 6 weeks of in vivo treatment of mice infected with E. multilocularis metacestodes (200 mg/kg of body weight/day) had no effect. However, combination treatments of both drugs with albendazole led to a substantial but statistically not significant reduction in parasite weight compared to results with albendazole alone.

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Dubinský, P., V. Svobodová, L. Turčeková, et al. "Echinococcus multilocularis in Slovak Republic: The first record in red foxes (Vulpes vulpes)." Helminthologia 36, no. 2 (1999): 105–10. https://doi.org/10.5281/zenodo.15091844.

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Echinococcus multilocularis was found for the first time in the Slovak Republic in 6 of 56 feaces of red foxes (Vulpes vul-pes) (prevalence 10.7%). Echinococcus spp. ceproantigens were detected using sandwich enzyme-linked immunosorbent assay (Ag-ELISA) in 6 of 28 red foxes (positivity 24. 4%). The gravid proglottides of E. multilocularis or cestode eggs of the Taenia-type were detected in five samples and eggs alone in one sample. The species of E. multilocularis was de-tected in three samples and comfirmed by using the nested PCR. This finding in the Slovak Republic indicated the risk o

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MOSS, J. E., X. CHEN, T. LI, et al. "Reinfection studies of canine echinococcosis and role of dogs in transmission of Echinococcus multilocularis in Tibetan communities, Sichuan, China." Parasitology 140, no. 13 (2013): 1685–92. http://dx.doi.org/10.1017/s0031182013001200.

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SUMMARYIn the eastern Tibetan plateau both human cystic and alveolar echinococcosis (AE) caused by infection with Echincoccus granulosus or Echinococcus multilocularis, respectively are highly endemic. The domestic dog plays a key role in zoonotic transmission in this region. Our primary objective was to investigate the role of domestic dogs in maintaining transmission of E. multilocularis in Shiqu county, Sichuan. A cohort of 281 dogs was followed up over one year after a single treatment with praziquantel followed by re-infection surveillance at 2, 5 and 12 months post-treatment. Faecal samp

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Moss, JE, X. Chen, T. Li, et al. "Reinfection studies of canine echinococcosis and role of dogs in transmission of Echinococcus multilocularis in Tibetan communities, Sichuan, China." Parasitology 140, no. 13 (2013): 1685–92. https://doi.org/10.1017/S0031182013001200.

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In the eastern Tibetan plateau both human cystic and alveolar echinococcosis (AE) caused by infection with Echincoccus granulosus or Echinococcus multilocularis, respectively are highly endemic. The domestic dog plays a key role in zoonotic transmission in this region. Our primary objective was to investigate the role of domestic dogs in maintaining transmission of E. multilocularis in Shiqu county, Sichuan. A cohort of 281 dogs was followed up over one year after a single treatment with praziquantel followed by re-infection surveillance at 2, 5 and 12 months post-treatment. Faecal samples wer

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Okamoto, M., Y. Oku, T. Kurosawa, and M. Kamiya. "Genetic Uniformity of Echinococcus multilocularis Collected from Different Intermediate Host Species in Hokkaido, Japan." Journal of veterinary medical science 69, no. 2 (2007): 159–63. https://doi.org/10.1292/jvms.69.159.

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DNA from several isolates of Taenia taeniaeformis and Echinococcus multilocularis were digested with restriction enzymes and hybridized with digoxigenated oligonucleotide probe (CAC)5. Within the six wild isolates of Taenia taeniaeformis from Norway rats in Hokkaido, although several bands were common among isolates, fingerprinting patterns were specific to each isolate. In the case of E. multilocularis, regardless of hosts from which each isolate has been isolated, the five isolates collected from Hokkaido, showed the same fingerprinting pattern. These results indicate that there was very lit

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Wang, Qian, Dominique A. Vuitton, Yongfu Xiao, et al. "Pasture Types And Echinococcus Multilocularis, Tibetan Communities." Emerging infectious diseases 12, no. 6 (2006): 1008–10. https://doi.org/10.5281/zenodo.15092030.

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Our study showed that open pastures had more small mammal burrows than fenced pastures in Tibetan pastoralist communities in 2003. This characteristic was linked to a higher prevalence of Echinococcus multilocularis in dogs and indicates that pasture type may affect E. multilocularis transmission.

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Nakao, M., T. Li, X. Han, et al. "Genetic polymorphisms of Echinococcus tapeworms in China as determined by mitochondrial and nuclear DNA sequences." International journal for parasitology 40, no. 3 (2010): 379–85. https://doi.org/10.1016/j.ijpara.2009.09.006.

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The genetic polymorphisms of Echinococcus spp. in the eastern Tibetan Plateau and the Xinjiang Uyghur Autonomous Region were evaluated by DNA sequencing analyses of genes for mitochondrial cytochrome c oxidase subunit 1 (cox1) and nuclear elongation factor-1 alpha (ef1a). We collected 68 isolates of Echinococcus granulosus sensu stricto (s.s.) from Xinjiang and 113 isolates of E. granulosus s. s., 49 isolates of Echinococcus multilocularis and 34 isolates of Echinococcus shiquicus from the Tibetan Plateau. The results of molecular identification by mitochondrial and nuclear markers were identi

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Martinek, K., L. Kolářová, E. Hapl, I. Literák, and M. Uhrin. "Echinococcus multilocularis in European wolves (Canis lupus)." Parasitology research 87 (June 7, 2001): 838–39. https://doi.org/10.1007/s004360100452.

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Nested PCR was used as a diagnostic tool to investigate the presence of Echinococcus multilocularis tapeworm in protected species of carnivores in Slovakia. Twenty-three faecal samples from wolves, four samples from bears and three samples from lynx from the Muránska Planina mountains and eight samples from wolves from the Bukovské Vrchy mountains were examined. E. multilocularis DNA was detected in two samples of wolves' faeces from the Muránska Planina mountains and one sample from the Bukovské Vrchy mountains. Examination of bears' and lynx faecal samples gave negative results. The detectio

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van, der Giessen JW, YB Rombout, JH Franchimont, LP Limper, and WL Homan. "Detection of Echinococcus multilocularis in foxes in The Netherlands." Veterinary parasitology 82, no. 1 (1999): 49–57. https://doi.org/10.1016/S0304-4017(98)00263-5.

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Echinococcus multilocularis was demonstrated in 5 out of 272 foxes in The Netherlands close to the border with Germany and Belgium. Besides microscopic examination of mucosal scrapings, two different PCR assays were used based on the detection of E. multilocularis DNA in colon content. Two distinct areas in The Netherlands were positive for E. multilocularis. Two positive foxes were found in the northern province of Groningen and three positive foxes were found in the southern province of Limburg. Both PCR assays detected more positive foxes compared to microscopic examination of the intestina

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Catalano, Stefano, Manigandan Lejeune, Stefano Liccioli, et al. "Echinococcus multilocularis in urban coyotes, Alberta, Canada." Emerging infectious diseases 18, no. 10 (2012): 1625–28. https://doi.org/10.3201/eid.1810.120119.

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Echinococcus multilocularis is a zoonotic parasite in wild canids. We determined its frequency in urban coyotes (Canis latrans) in Alberta, Canada. We detected E. multilocularis in 23 of 91 coyotes in this region. This parasite is a public health concern throughout the Northern Hemisphere, partly because of increased urbanization of wild canids.

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Miterpáková, M., D. Antolová, Z. Ševčíková, et al. "Echinococcus multilocularis in musk rat (Ondatra zibethicus): the first finding of the parasite in naturally infected rodent in the Slovak Republic." Helminthologia 43, no. 2 (2006): 76–80. http://dx.doi.org/10.2478/s11687-006-0015-z.

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AbstractInfection with the larval stage of Echinococcus multilocularis was diagnosed in musk rat (Ondatra zibethicus) in the Slovak Republic. At necropsy, massively enlarged liver with numbers of abscess-like lesions up to 1.5 cm in diameter was found. Histological examination shoved the presence of typical multivesicular cysts with multiple protoscoleces and typical laminated layer. Polymerase chain reaction confirmed the diagnosis. According to our knowledge, this is the first documentation of Echinococcus multilocularis in naturally infected rodent in territory of the Slovak Republic.

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Zhang, Yalou, Jean-Mathieu Bart, Patrick Giraudoux, Philip Craig, Dominique Vuitton, and Hao Wen. "Morphological and molecular characteristics of Echinococcus multilocularis and Echinococcus granulosus mixed infection in a dog from Xinjiang, China." Veterinary parasitology 139, no. 3-Jan (2006): 244–8. https://doi.org/10.1016/j.vetpar.2006.03.003.

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The Xinjiang plateau of western China has been shown to have a high prevalence for human cystic echinococcosis (CE) caused by Echinococcus granulosus, and human alveolar echinococcosis (AE) caused by Echinococcus multilocularis. The domestic dog is suspected to be the primary definitive host for the transmission of both E. granulosus and E. multilocularis to humans in this locality. Seventeen of 30 stray dogs from Hejing County of Xinjiang were found positive for E. granulosus post mortem, and one double infection was suspected. Worm samples were collected, dyed by carmine, and observed micros

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Takahashi, K., and K. Nakata. "Note on the first occurrence of larval Echinococcus multilocularis in Clethrionomys rex in Hokkaido, Japan." Journal of Helminthology 69, no. 3 (1995): 265–66. http://dx.doi.org/10.1017/s0022149x00014255.

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AbstractLarval Echinococcus multilocularis was found in Clethrionomys rex in Hokkaido, Japan. C. rex is a new host record for E. multilocularis. The cysts were filled with numerous protoscoleces suggesting a potential role of this vole in a natural cycle of transmission.

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Takahashi, K., and K. Nakata. "Note on the first occurrence of larval Echinococcus multilocularis in Clethrionomys rex in Hokkaido, Japan." Journal of helminthology 69, no. 3 (1995): 265–6. https://doi.org/10.5281/zenodo.15091798.

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Larval Echinococcus multilocularis was found in Clethrionomys rex in Hokkaido, Japan. C. rex is a new host record for E. multilocularis. The cysts were filled with numerous protoscoleces suggesting a potential role of this vole in a natural cycle of transmission.

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43

Sedleckaitė, Kotryna. "ECHINOKOKOZĖ: KLINIKA IR DIFERENCINĖ DIAGNOSTIKA." Health Sciences 32, no. 3 (2022): 172–74. http://dx.doi.org/10.35988/sm-hs.2022.115.

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Echinokokozė tai parazitinė liga, sukeliama kaspinuočių, priklausančių echinokokų rūšiai. Žmonės gali susirgti dviejų pagrindinių tipų liga – cistine echinokokoze, kurią sukelia Echinococcus granulosus arba alveoline echinokokoze, kurią sukelia ir Echinococcus multilocularis. E. Granulosus pradinė pirminės infekcijos fazė visada yra besimptomė. Šiuo parazitu dažniausiai yra užsikrečiama vaikystėje ir dažnai žmogus nežino, kad yra užsikrėtęs. E. multilocularis infekcija dažniau būna simptominė ir pasireiškimu primena onkologinę ligą. Šio parazitinio susirgimo diferencinei diagnostikai naudoj

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Xin, Qi, Wei Lv, Yunxi Xu, et al. "2-Deoxy-D-glucose and combined 2-Deoxy-D-glucose/albendazole exhibit therapeutic efficacy against Echinococcus granulosus protoscoleces and experimental alveolar echinococcosis." PLOS Neglected Tropical Diseases 16, no. 7 (2022): e0010618. http://dx.doi.org/10.1371/journal.pntd.0010618.

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2-Deoxy-D-glucose (2-DG) is a glucose analog used as a promising anticancer agent. It exerts its effects by inhibiting the glycolytic energy metabolism to deplete cells of energy. The larval stage of Echinococcus relies on glycolysis for energy production. Therefore, in this study, we investigated the in vitro and in vivo efficacy of 2-DG against the larval stage of Echinococcus granulosus and E. multilocularis. 2-DG exhibited significant time- and dose-dependent effects against in vitro cultured E. granulosus protoscoleces and E. multilocularis metacestodes. A daily oral administration of 500

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Nonaka, N., M. Kamiya, F. Kobayashi, et al. "Echinococcus Multilocularis Infection In Pet Dogs In Japan." Vector borne and zoonotic diseases (Larchmont, N.Y.) 9, no. 2 (2009): 201–6. https://doi.org/10.1089/vbz.2008.0097.

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A survey of Echinococcus multilocularis infections in pet dogs in Japan from 1997 to 2007 was conducted by testing for coproantigen reactivity, fecal taeniid eggs, and egg DNA. In Hokkaido, the only island where E. multilocularis is endemic in Japan, 18 of 4768 dogs (0.4%) excreted taeniid eggs that were positive for E. multilocularis DNA by polymerase chain reaction (PCR). Most of the dogs testing positive for egg DNA were kept free-range, but three dogs had been kept inside their owners' houses. In addition, 15 dogs were suspected to be infected based on the results of a coproantigen test. O

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Kaethner, Marc, Georg Rennar, Tom Gallinger, et al. "In Vitro Activities of Dithiocarbamate Derivatives against Echinococcus multilocularis Metacestode Vesicles." Tropical Medicine and Infectious Disease 8, no. 12 (2023): 517. http://dx.doi.org/10.3390/tropicalmed8120517.

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The metacestode stage of the fox tapeworm Echinococcus multilocularis causes the severe zoonotic disease alveolar echinococcosis. New treatment options are urgently needed. Disulfiram and dithiocarbamates were previously shown to exhibit activity against the trematode Schistosoma mansoni. As both parasites belong to the platyhelminths, here we investigated whether these compounds were also active against E. multilocularis metacestode vesicles in vitro. We used an in vitro drug-screening cascade for the identification of novel compounds against E. multilocularis metacestode vesicles with disulf

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AVCIOGLU, HAMZA, ESIN GUVEN, IBRAHIM BALKAYA, et al. "First detection of Echinococcus multilocularis in rodent intermediate hosts in Turkey." Parasitology 144, no. 13 (2017): 1821–27. http://dx.doi.org/10.1017/s0031182017001226.

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SUMMARYEchinococcus multilocularis is the causative agent of alveolar echinococcosis (AE), a potentially fatal zoonotic disease. Large parts of Turkey are considered as endemic for E. multilocularis. The aim of this study was to determine the occurrence of metacestode of E. multilocularis in wild rodents in Erzurum, an endemic region for human AE in Turkey. During the sampling period, a total of 498 rodents were trapped in twenty counties of Erzurum Province. Suspected lesions were observed on the livers of 48 rodents, and then partial fragment of mitochondrial 12S rRNA gene was PCR-amplified.

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Avcioglu, Hamza, Esin Guven, Ibrahim Balkaya, et al. "First detection of Echinococcus multilocularis in rodent intermediate hosts in Turkey." Parasitology 144, no. 13 (2017): 1821–27. https://doi.org/10.1017/S0031182017001226.

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Echinococcus multilocularis is the causative agent of alveolar echinococcosis (AE), a potentially fatal zoonotic disease. Large parts of Turkey are considered as endemic for E. multilocularis. The aim of this study was to determine the occurrence of metacestode of E. multilocularis in wild rodents in Erzurum, an endemic region for human AE in Turkey. During the sampling period, a total of 498 rodents were trapped in twenty counties of Erzurum Province. Suspected lesions were observed on the livers of 48 rodents, and then partial fragment of mitochondrial 12S rRNA gene was PCR-amplified. Five l

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Barth, Thomas F. E., and Adriano Casulli. "Morphological Characteristics of Alveolar and Cystic Echinococcosis Lesions in Human Liver and Bone." Pathogens 10, no. 10 (2021): 1326. http://dx.doi.org/10.3390/pathogens10101326.

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Among echinococcoses diseases of human interest, two have a global public health impact: cystic and alveolar echinococcosis caused by Echinococcus granulosus sensu lato and Echinococcus multilocularis, respectively. Cystic and alveolar echinococcosis are neglected infectious diseases epidemiologically and are clinically vastly different with distinct microscopic features. Because of the rareness of these zoonotic diseases, pathologists have limited diagnostic experience in the analysis of the lesions caused by Echinococcus tapeworms. Here, we describe the main microscopic features to be consid

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50

Liance, Martine, Veronique Janin, Solange Bresson-Hadni, Dominique-Angele Vuitton, Rene Houin, and Renaud Piarroux. "Immunodiagnosis of EchinococcusInfections: Confirmatory Testing and Species Differentiation by a New Commercial Western Blot." Journal of Clinical Microbiology 38, no. 10 (2000): 3718–21. http://dx.doi.org/10.1128/jcm.38.10.3718-3721.2000.

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The Echinococcus Western Blot IgG (LDBIO Diagnostics, Lyon, France), using a whole larval antigen from Echinococcus multilocularis, was evaluated for serodiagnosis and differentiation between two human parasitic infections of worldwide importance: cystic echinococcosis, due to Echinococcus granulosus, and alveolar echinococcosis, due to E. multilocularis. Fifty and 61 serum samples from patients with cystic and alveolar echinococcosis, respectively, were used for assessing diagnostic sensitivity. The sensitivity of the assay was compared with those of screening tests used for these application

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