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Journal articles on the topic 'Eclampsia twin pregnancies'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Laine, Katariina, Gulim Murzakanova, Kristina Baker Sole, Aase Devold Pay, Siri Heradstveit, and Sari Räisänen. "Prevalence and risk of pre-eclampsia and gestational hypertension in twin pregnancies: a population-based register study." BMJ Open 9, no. 7 (2019): e029908. http://dx.doi.org/10.1136/bmjopen-2019-029908.

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ObjectivesThe aim of this study was to assess the prevalence and risk of pre-eclampsia and gestational hypertension in twin pregnancies compared with singleton pregnancies.DesignPopulation-based cohort study.SettingMedical Birth Registry of Norway and Statistics Norway.Participants929 963 deliveries with 16 174 twin pregnancies in 1999–2014.MethodsPre-eclampsia prevalences in twin and singleton pregnancies were described in percentages. Multivariable regression analyses were performed to assess the risks of pre-eclampsia and gestational hypertension in twin pregnancies compared with those in s

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Gortazar, Lucia, Juana Antonia Flores-Le Roux, David Benaiges, et al. "Trends in Prevalence of Diabetes among Twin Pregnancies and Perinatal Outcomes in Catalonia between 2006 and 2015: The DIAGESTCAT Study." Journal of Clinical Medicine 10, no. 9 (2021): 1937. http://dx.doi.org/10.3390/jcm10091937.

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The aims of our study were to evaluate the trends in the prevalence of diabetes among twin pregnancies in Catalonia, Spain between 2006 and 2015, to assess the influence of diabetes on perinatal outcomes of twin gestations and to ascertain the interaction between twin pregnancies and glycaemic status. A population-based study was conducted using the Spanish Minimum Basic Data Set. Cases of gestational diabetes mellitus (GDM) and pre-existing diabetes were identified using ICD-9-CM codes. Data from 743,762 singleton and 15,956 twin deliveries between 2006 and 2015 in Catalonia was analysed. Amo

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Prins, Taco J., Aung Myat Min, Mary E. Gilder, et al. "Comparison of perinatal outcome and mode of birth of twin and singleton pregnancies in migrant and refugee populations on the Thai Myanmar border: A population cohort." PLOS ONE 19, no. 4 (2024): e0301222. http://dx.doi.org/10.1371/journal.pone.0301222.

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Background In low- and middle-income countries twin births have a high risk of complications partly due to barriers to accessing hospital care. This study compares pregnancy outcomes, maternal and neonatal morbidity and mortality of twin to singleton pregnancy in refugee and migrant clinics on the Thai Myanmar border. Methods A retrospective review of medical records of all singleton and twin pregnancies delivered or followed at antenatal clinics of the Shoklo Malaria Research Unit from 1986 to 2020, with a known outcome and estimated gestational age. Logistic regression was done to compare th

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Natália, Garcia Adorno, Mertz Araújo Gabriela, Clara Ayoroa Freire Ana, et al. "Management Of Twin Pregnancies And The Risk Of Fetal Death." INTERNATIONAL JOURNAL OF HEALTH & MEDICAL RESEARCH 03, no. 07 (2024): 488–94. https://doi.org/10.5281/zenodo.12799811.

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Introduction: Twin pregnancies can present risks to both mother and fetus. One of the biggest concerns in twin pregnancies is premature birth.Objectives: To discuss the management of twin pregnancies in order to avoid fetal death. Material and Methods: The methodology used was a literature review. The research was carried out through an electronic search of scientific articles published between 2010 and 2024.Discussion: Complications such as premature birth, pre-eclampsia, intrauterine growth restriction and gestational diabetes are more common in twin pregnancies. Reducing these complications

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Hwang, Jong Yun. "Obstetricians’ Utilization of Risk Factors for High-Risk Pregnancy to Predict Complicated Pregnancies: How Are Obstetricians Using Risk Factors for High-Risk Pregnancy?" Journal of Korean Maternal and Child Health 28, no. 2 (2024): 75–83. http://dx.doi.org/10.21896/jkmch.2024.28.2.75.

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Purpose: The aim of this study was to analyze how obstetricians use risk factors for high-risk pregnancies to predict complicated pregnancies.Methods: Twenty-four obstetricians were surveyed using a questionnaire that included 75 high-risk pregnancy factors identified by the Korean Society of Obstetrics and Gynecology. These factors are used to predict 11 types of complicated pregnancies: preterm labor, preterm premature rupture of membranes, incompetent internal os of the cervix, placenta previa, placenta abruptio, postpartum hemorrhage, preeclampsia/eclampsia, oligohydramnios, polyhydramnios

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Sekhasaria, Priyanka, Rama S. Chundawat, Suman Shivrayan, Akanksha Agarwal, and Balveer Jakhar. "Study of maternal and perinatal outcomes in twin pregnancies delivered at a tertiary centre hospital in Southern Rajasthan." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 13, no. 12 (2024): 3685–90. http://dx.doi.org/10.18203/2320-1770.ijrcog20243605.

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Background: Twin pregnancy occurs when two babies are growing inside the uterus. The idea of twinning has fascinated people for as long as humans have been writing history. The primary concerns that arise during twin pregnancies include congenital malformations, birth trauma, birth asphyxia, intrauterine growth restriction (IUGR), premature birth, and low birth weight. The main factor that poses the highest risk is premature birth, which is mainly responsible for the higher chances of perinatal death, neonatal illness, and long-term problems in twins. Methods: A total of 48 twin pregnant women

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Hebbar, Shripad, and Sonam Agarwal. "A comparative study of performance of first trimester FMF algorithm for prediction of preeclampsia in singleton and twin pregnancies in coastal Karnataka." Indian Journal of Obstetrics and Gynecology Research 10, no. 4 (2023): 439–44. http://dx.doi.org/10.18231/j.ijogr.2023.084.

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Preeclampsia is one of the most common disorders of pregnancy known to complicate 5-10% of all the pregnancies, and it is a component of the deadly triad (along with haemorrhage and infection), that contributes greatly to maternal morbidity and mortality rates. The prevalence of preeclampsia in twin pregnancy is 3-4 fold compared to singleton pregnancy. Timely diagnosis and prevention of this condition is therefore critical. Multiple maternal factors and placental biomarkers have shown to predict preeclampsia in singleton pregnancies. Previous Studies have shown that the proposed algorithms fo

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Sapantzoglou, Ioakeim, Angeliki Rouvali, Antonios Koutras, et al. "sFLT1, PlGF, the sFLT1/PlGF Ratio and Their Association with Pre-eclampsia in Twin Pregnancies—A Review of the Literature." Medicina 59, no. 7 (2023): 1232. http://dx.doi.org/10.3390/medicina59071232.

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Twin pregnancies demonstrate a 2–3-fold higher chance of developing PE compared to singletons, and recent evidence has demonstrated that the sFLT1/PIGF ratio is strongly associated with PE, adverse pregnancy outcomes, as well as imminent deliveries due to PE complications. The primary objective of this systematic review was to summarise the available data on the levels of sFLT1, PlGF and their ratios in twin pregnancies and to investigate their association with the development of PE, adverse pregnancy outcomes and the timing of the delivery. A systematic search of Ovid Embase, Web of Science,

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黄, 茹. "Prediction of Factors Affecting Pre-Eclampsia in Twin Pregnancies." Advances in Clinical Medicine 13, no. 09 (2023): 14020–24. http://dx.doi.org/10.12677/acm.2023.1391960.

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10

Campbell, D. M., and A. J. Campbell. "Arterial Blood Pressure - The Pattern of Change in Twin Pregnancies." Acta geneticae medicae et gemellologiae: twin research 34, no. 3-4 (1985): 217–23. http://dx.doi.org/10.1017/s0001566000004773.

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AbstractAn epidemiological study of all primigravid twin pregnancies delivered in Aberdeen between 1950 and 1969 was performed to determine the pattern of arterial blood pressure changes. There is a greater fall from non-pregnant levels in diastolic blood pressure by mid pregnancy and a greater rise of diastolic pressure by delivery. These changes are independent of age, body size and rate of weight gain during pregnancy. The expected increased incidence of proteinuric pre-eclampsia is also independent of rate of weight gain when defined for twin pregnancies.

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Ari Lestari, Nur Cahyani, Syahrida Wahyu Utami, and Reni Rahayu. "Hubungan Faktor Resiko Dengan Kejadian Eklampsia Pada Ibu Hamil di RSUD Ambarawa." JOURNAL EDUCATIONAL OF NURSING(JEN) 2, no. 2 (2019): 7–17. http://dx.doi.org/10.37430/jen.v2i2.38.

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Eclampsia is a pregnancy-specific syndrome in the form of decreased organ perfusion due to vasospasm and endothelial activation, characterized by increased blood pressure, proteinuria, with or without edema accompanied by seizures. Eclampsia can harm the mother and fetus. The exact cause of eclampsia is unknown, but eclampsia can be triggered by several risk factors including the age of too young or too young, nulliparous, obesity in pregnancy, chronic hypertension, diabetes and multiple pregnancies. This study aims to determine the relationship between risk factors and the incidence of eclamp

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Nkyekyer, Kobinah. "Twin and Singleton Births in Ghana — A Case-control Study." Twin Research 5, no. 4 (2002): 265–69. http://dx.doi.org/10.1375/twin.5.4.265.

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AbstractAretrospective study involving 623 twin and 1246 singleton births was conducted to compare the two groups with regard to selected maternal, fetal and labor and delivery characteristics and outcomes. Maternal age and parity were significantly higher for twins. The risks of preterm delivery, arrival in the labor ward in second stage of labor, cesarean births and postpartum haemorrhage were significantly higher in twin than in singleton births. In vaginal deliveries twin mothers were significantly less likely to have had episiotomies or perineal lacerations. There was no difference in the

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Kalafat, Erkan, Aisha Abiola, Basky Thilaganathan, Amar Bhide, and Asma Khalil. "The Association Between Hypertension in Pregnancy and Preterm Birth with Fetal Growth Restriction in Singleton and Twin Pregnancy: Use of Twin Versus Singleton Charts." Journal of Clinical Medicine 9, no. 8 (2020): 2518. http://dx.doi.org/10.3390/jcm9082518.

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Objective: To compare the rates of fetal growth restriction (FGR) in singleton and twin pregnancies using singleton and twin-specific birthweight standards. Methods: The study included liveborn twin and singleton pregnancies between January 2000 and January 2019. Hypertensive disorders of pregnancy (HDP) included gestational hypertension and pre-eclampsia. The study outcomes were FGR or small-for-gestational-age (SGA) at birth as assessed using singleton and twin reference charts. Results: The analysis included 1473 twin and 62,432 singleton pregnancies. In singleton pregnancies the risk of PT

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Tombetti, E., V. Ramoni, M. Betelli, et al. "OP0175 INTERNATIONAL MULTICENTRIC PROSPECTIVE STUDY ON PREGNANCY IN SYSTEMIC SCLEROSIS (IMPRESS-2)." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 105.1–105. http://dx.doi.org/10.1136/annrheumdis-2021-eular.4273.

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Background:Data about the obstetric outcomes of pregnant women with Systemic Sclerosis (SSc) mainly derive from retrospective studies. Moreover, little evidence is available to define if pregnancy impacts on SSc course and if children of SSc mothers have a normal post-natal development.Objectives:To assessed the obstetric, pediatric and rheumatologic outcomes of SSc pregnancies in a prospective controlled studyMethods:Prospective recruitment of three cohorts.1) 110 pregnant women with SSc.2) 218 control pregnancies without systemic autoimmune diseases3) 78 non-pregnant control SSc with a match

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Belotserkovtseva, L. D., L. V. Kovalenko, I. A. Kudrinskikh, I. I. Mordovina, V. A. Starodumova, and E. A. Shchepkina. "Role of placental pathomorphological changes in the pathogenesis of early pre-eclampsia in twin and singleton pregnancies." Voprosy ginekologii, akušerstva i perinatologii 21, no. 4 (2022): 21–28. http://dx.doi.org/10.20953/1726-1678-2022-4-21-28.

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Objective. To compare the features of placental pathology in twin and singleton pregnancies complicated by early preeclampsia. Materials and methods. A retrospective analysis of 211 placental pathomorphological examinations in patients with early preeclampsia was performed. The first (study) group composed of placentas obtained from patients with twin pregnancy and early pre-eclampsia (n = 108); the second (comparison) group composed of placentas obtained from patients with singleton pregnancy and early pre-eclampsia (n = 103). Placental histopathological examination was conducted according to

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Krotz, Stephan, Javier Fajardo, Sanjay Ghandi, Ashlesha Patel, and Louis G. Keith. "Hypertensive Disease in Twin Pregnancies: A Review." Twin Research 5, no. 1 (2002): 8–14. http://dx.doi.org/10.1375/twin.5.1.8.

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AbstractReports over the past seventy years show that twin gestations lead to an increased risk of hypertensive disorders. Numerous studies discuss the incidence of hypertensive disease in twin versus singleton gestations, as well as effects of parity, race, age, income level, smoking, zygosity and heritability on this condition. The range of relative risk of gestational hypertension, preeclampsia and eclampsia for twin compared to singleton gestations is 1.2 to 2.7, 2.8 to 4.4 and 3.4 to 5.1 respectively. Parity, African-American ethnicity, and young maternal age are all factors that increase

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Ghosh, Deepti, Subhra Samantroy, Deepti D. Pradhan, and Jayashree J. Moharana. "Optimizing delivery timing in selective fetal growth restricted dichorionic diamniotic twins: lessons from a case series." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 14, no. 6 (2025): 1932–39. https://doi.org/10.18203/2320-1770.ijrcog20251585.

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Authors aim to analyze the maternal and fetal outcomes in IVF -conceived dichorionic diamniotic (DCDA) twin pregnancies complicated by FGR in women of advanced maternal age, focusing on complications and management strategies. A retrospective analysis of five IVF-conceived DCDA twin pregnancies in women aged 30-49 years was conducted at our tertiary care center between August-October 2024. Establishment of presence of FGR in one or both twins, was done using Delphi criteria. Cases underwent systematic monitoring via serial ultrasound scans with Doppler and comprehensive maternal-fetal surveill

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Bartnik, Pawel, Katarzyna Kosinska-Kaczynska, Joanna Kacperczyk, et al. "Twin Chorionicity and the Risk of Hypertensive Disorders: Gestational Hypertension and Pre-eclampsia." Twin Research and Human Genetics 19, no. 4 (2016): 377–82. http://dx.doi.org/10.1017/thg.2016.17.

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Twin gestation is known to be a risk factor for hypertensive disorders of pregnancy. However, the relationship between hypertensive disorders (pre-eclampsia (PE) and gestational hypertension (GH)) and chorionicity of twin pregnancy is unclear, and published data is conflicting. We decided to analyze the relationship between placentation and prevalence of hypertensive disorders. It was a retrospective cohort study. 312 twin pregnancies delivered between 2009 and 2014 were analyzed, 79 of which were monochorionic and 233 dichorionic. The occurrence of PE and GH was established according to Ameri

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Barman, Lisa, Mamta Bhardwaj, and Ritika Chugh. "Successful Resuscitation of a Young Maternal Cardiac Arrest with Twin Pregnancy: A Case Report." Journal of Obstetric Anaesthesia and Critical Care 14, no. 1 (2024): 81–83. http://dx.doi.org/10.4103/joacc.joacc_15_23.

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Cardiopulmonary arrest in pregnancy is one of the most dreadful situations for clinicians. Along with physiological changes in pregnancy, the time constraint to save both lives makes this situation impeccably difficult to manage. Here, we present a case of successful resuscitation of a young mother with twin pregnancies who was diagnosed with pre-eclampsia and was under antihypertensive therapy for 4 days. Evidently, a multidisciplinary approach, rapid response and timely intervention can alleviate both the maternal and neonatal mortality rate in pregnancies landing up on cardiopulmonary resus

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Davies, Michael J. "Fetal programming: the perspective of single and twin pregnancies." Reproduction, Fertility and Development 17, no. 3 (2005): 379. http://dx.doi.org/10.1071/rd04101.

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Multiple pregnancy is associated with increased risk of adverse consequences for both mother and fetus(es), including increased rates of maternal hypertension and pre-eclampsia, spontaneous abortion, Caesarean delivery, low birthweight, birth prematurity, perinatal mortality, admission to neonatal intensive care and extended length of care, respiratory distress, cerebral palsy, developmental delay, contact with disability services and mortality to age 5 years. Premature birth, which affects 97% of triplets and 53.3% of twins in Australia, is not the sole factor involved. The rate of multiple p

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Ruppen, Ian Caldeira, Ana Claudia Mansano Girotto, Renam Arthur de Sousa, et al. "Multiple Pregnancies: Complications and Management – A Brief Review." American Journal of Medical and Clinical Research & Reviews 04, no. 06 (2025): 01–04. https://doi.org/10.58372/2835-6276.1303.

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Multiple pregnancies, defined by the simultaneous presence of two or more fetuses, represent a high‑complexity obstetric challenge whose incidence has been rising worldwide. This increase is driven mainly by delayed childbearing and the expanded use of assisted reproductive technologies. Maternal physiological overload and competition for nutrients among fetuses elevate the frequency of complications, notably gestational hypertension, pre‑eclampsia, gestational diabetes, and anemia. In addition, venous thromboembolism and postpartum hemorrhage occur more often. From the fetal standpoint, prema

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Putri Arifin, Reny Faristin, Via Rustiani, and Wildan Firmansyah. "Preeclampsia in Multiples: A Comparative Case Study on Dichorionic-Diamniotic Twin Pregnancy." Jurnal Indonesia Sosial Teknologi 5, no. 5 (2024): 2229–34. http://dx.doi.org/10.59141/jist.v5i5.1096.

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Multiple pregnancies have a 2-3 times greater risk of developing preeclampsia and have a significant long-term effect on both mothers and babies. The underlying cause of preeclampsia in women with multiple pregnancies is higher demand on the cardiovascular system, increased exposure of the chorionic villi, increased antiangiogenic substances compared to angiogenic substances and placental hypoperfusion. The condition of preeclampsia can worsen quickly, and without warning signs, it must be detected and managed appropriately; if the treatment is late, this condition can lead to eclampsia. The p

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Danaee, Anicee, Susan Robinson, Steven Okoli, Pippa Kyle, Matias Costa Vieira, and Dharmintra Pasupathy. "Incidence and Aetiology of Thrombocytopenia in Twin Pregnancies in a Tertiary Referral Centre." Blood 124, no. 21 (2014): 4188. http://dx.doi.org/10.1182/blood.v124.21.4188.4188.

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Abstract Introduction Thrombocytopenia is well described in pregnancy with an incidence of 6-10%. The majority of data with regards to platelet counts in pregnancy and aetiology of pregnancy related thrombocytopenia, however, derives from studies conducted in singletons. There is little information available on this subject in higher order pregnancies. Aim This longitudinal study aims to identify the incidence and aetiology of thrombocytopenia in twin pregnancies in order to guide investigation and management. As a reference we also investigate changes in platelet counts in a cohort of uncompl

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Croft, Maxine L., Vera Morgan, Anne W. Read, and Assen S. Jablensky. "Recorded Pregnancy Histories of the Mothers of Singletons and the Mothers of Twins: A Longitudinal Comparison." Twin Research and Human Genetics 13, no. 6 (2010): 595–603. http://dx.doi.org/10.1375/twin.13.6.595.

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A population-based record linkage case cohort of 239,995 births, to 119,214 women, born in Western Australia from 1980 to 2001 inclusive, was used to measure the recording of selected indicators of maternal health (current and prior) during pregnancy. We compared records of women with singleton pregnancies with that in twin pregnancies Mothers of first- and second-born singletons (n= 117,647) were compared with women with a first-born singleton followed by twins (n= 1,567). Binary indicators were used to calculate population prevalence of medical conditions, pregnancy complications and birth o

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International, Journal of Medical Science and Innovative Research (IJMSIR). "Comparison of Joel-Cohen Incision and Pfannenstiel Incision for Caesarean Section." International Journal of Medical Science and Innovative Research (IJMSIR) 9, no. 6 (2024): 51–58. https://doi.org/10.5281/zenodo.15449475.

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<strong>Abstract</strong> <strong>Introduction</strong>: Caesarean section is a widely performed surgical procedure for women globally, aimed at reducing maternal and fetal risks. This is particularly important as emergency C-sections are associated with multiple complications compared to vaginal deliveries and choice of abdominal incision has been correlated with incidence of complications. <strong>Aim</strong>: The objective of this study is to compare the outcomes of the Joel-Cohen incision and the Pfannenstiel incision in caesarean section procedures. <strong>Methodology</strong>: This hos

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Rajsekher, Monishaa, and Palaniappan Narayanan. "Turning a Turner to a twin mother." BMJ Case Reports 14, no. 6 (2021): e242470. http://dx.doi.org/10.1136/bcr-2021-242470.

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Women with Turner syndrome (TS) are subfertile due to premature ovarian insufficiency. Most women require hormone replacement therapy for attaining menarche and assisted reproductive technology (ART) using donor oocytes, autologous oocytes or in-vitro fertilisation for conception. Irrespective of the karyotype, monosomy X (45, X) or mosaic pattern, women with TS hold a very high risk for pregnancy due to high mortality rate secondary to aortic dissection and severe pre-eclampsia. Such high-risk pregnancies mandate extensive prepregnancy counselling, the need for multidisciplinary teams, close

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Shim, Sohyun, Yoon-Mi Hur, Da Hee Kim, Seok Ju Seong, Mi-La Kim, and Joong Sik Shin. "Evidence for No Significant Impact of Müllerian Anomalies on Reproductive Outcomes of Twin Pregnancy in Korean Women." Twin Research and Human Genetics 19, no. 2 (2016): 146–53. http://dx.doi.org/10.1017/thg.2016.4.

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The present article aimed to evaluate the impact of congenital Müllerian anomalies (MA) on twin pregnancy after 24 gestational weeks in Korean women. All records of twin pregnancies in a large maternity hospital in Korea between January 2005 and July 2013 were analyzed. Patients with monochorionic monoamniotic (MCMA) twins, non-Korean patients, patients with twins delivered prior to 24 gestational weeks, and patients with miscarriage of one fetus or intrauterine fetal death (IUFD) before 24 gestational weeks were excluded from data analysis. In total, 1,422 women with twin pregnancy were eligi

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Ara, Dr Anjuman, Dr Mahbuba Akhter, Dr Sanjida Khan, Dr Sanjida Akhter, Lt Co Dr Mahammed Nurzzaman Bhuiyan, and Dr Jebunnesa Dr. Jebunnesa. "Feto-Meternal Outcome of Twin Pregnancy: A Retrospective Study at the Centre for Woman and Child Health, Dhaka, Bangladesh." Scholars Journal of Applied Medical Sciences 9, no. 6 (2021): 846–50. http://dx.doi.org/10.36347/sjams.2021.v09i06.014.

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Background: Multiple pregnancies constitute an important portion of high-risk pregnancies and are a matter of grave concern to obstetricians and pediatricians owing to maternal and perinatal morbidity and mortality associated with it. We have very little research-based information regarding the maternal and perinatal outcomes of twin pregnancy. Aim of the study: The aim of this present study was to evaluate the maternal and perinatal outcomes of twin pregnancy. Methods: This cross-sectional observational study was conducted under the Department of Obstetrics & Gynaecology at The Center for

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Lenny Sijabat, Idona Gokmarina, Firma Simatupang, Siska Suci Triana Ginting, and Vidya Silvyani Audry. "FAKTOR-FAKTOR YANG MEMPENGARUHI KEJADIAN PERSALINAN PREMATUR DI RSIA STELLA MARIS MEDAN TAHUN 2022." Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran 1, no. 1 (2022): 22–31. http://dx.doi.org/10.55606/termometer.v1i1.949.

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Background: Preterm/preterm delivery is still a problem in the world including Indonesia, related to prevalence, morbidity and perinatal mortality which is the main cause of infant death and the second cause of death after pneumonia in children under five years of age. This study aims to determine the factors that influence the incidence of preterm labor at Rsia Stella Maris Medan in 2022. Method: This type of research is a descriptive study, with a cross-sectional design. Sampling was carried out systematically (systematic random sampling), where the sample in this study was 64 respondents. D

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Wanyoike, J. G., and S. Ndegwa. "Use of gestational surrogacy for a patient with recurrent pregnancy loss from early onset of severe pre-eclampsia: Case report." Journal of Obstetrics and Gynaecology of Eastern and Central Africa 32, no. 2 (2020): 3–5. http://dx.doi.org/10.59692/jogeca.v32i2.207.

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Introduction: The use of a gestational carrier deserves consideration as a treatment option in patients with poor reproductive histories because of early onset severe pre-eclampsia (PET) and hemolysis, elevated liver enzymes, and low platelets syndrome (HELLP). The case report is of 33 years old woman and 35 years old husband who presented with bad obstetric outcome of 7 pregnancies losses in the second trimester due to severe PET. After the 7th pregnancy loss, the couple opted for gestational surrogacy. In a traditional surrogacy arrangement, the surrogate mother provides the oocyte and the u

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Wanyoike, J. G., and S. Ndegwa. "Use of gestational surrogacy for a patient with recurrent pregnancy loss from early onset of severe pre-eclampsia: Case report." Journal of Obstetrics and Gynaecology of Eastern and Central Africa 32, no. 2 (2020): 3–5. http://dx.doi.org/10.59692/jogeca.v32i2.231.

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Introduction: The use of a gestational carrier deserves consideration as a treatment option in patients with poor reproductive histories because of early onset severe pre-eclampsia (PET) and hemolysis, elevated liver enzymes, and low platelets syndrome (HELLP). The case report is of 33 years old woman and 35 years old husband who presented with bad obstetric outcome of 7 pregnancies losses in the second trimester due to severe PET. After the 7th pregnancy loss, the couple opted for gestational surrogacy. In a traditional surrogacy arrangement, the surrogate mother provides the oocyte and the u

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DUMINICĂ-TURCU, Ana, Nicolae GICĂ, Brînduşa Ana CIMPOCA-RAPTIS, et al. "Hypertensive disorders in twin pregnancy." Romanian Journal of Medical Practice 16, S3 (2021): 32–35. http://dx.doi.org/10.37897/rjmp.2021.s3.7.

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Hypertensive disorders such as gestational hypertension, preeclampsia, eclampsia and HELLP syndrome are one of the most common pregnancy-associated entities that imply substantial maternal-fetal mortality and morbidity. When hypertensive disorders are associated with a multiple pregnancy, the outset is established sooner, with a rapid evolution and a more severe development. Although, the pathophysiology of hypertensive disorders is not fully understood, there are several risk factors that could be identified. A multiple pregnancy implies additional risks due to specific features: larger or mu

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International, Journal of Medical Science and Innovative Research (IJMSIR). "A study of maternal and perinatal outcome in women with multiple pregnancy in a tertiary care hospital." International Journal of Medical Science and Innovative Research (IJMSIR) 9, no. 3 (2024): 30–36. https://doi.org/10.5281/zenodo.15406637.

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<strong>Abstract</strong> <strong>Background: </strong>The incidence of twin pregnancy has steadily increased due to rising maternal age and increases demand for fertility treatments. Multifetal pregnancies are associated with higher maternal and perinatal complications. <strong>Methods: </strong>This is a descriptive observational study carried out in Department of Obstetrics and Gynaecology National Institute of Medical Sciences, Jaipur Rajasthan, over the period of two years i.e. May 2022 to April 2024. <strong>Result: </strong>The incidence of multiple pregnancies is 25.68/1000 deliveries,

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Ibrahimou, Boubakari, Cynthia Anozie, Cara de la Cruz, and Hamisu Salihu. "Previous Preterm Birth and Current Maternal Complications as a Risk Factor of Subsequent Stillbirth." Advances in Epidemiology 2015 (July 30, 2015): 1–6. http://dx.doi.org/10.1155/2015/819146.

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Purpose. To examine the association between previous preterm birth and the risk of stillbirth. Methods. This population-based retrospective cohort study analyzed live births and stillbirth records in Missouri (1989–1997). The main outcome of interest was stillbirth occurrence while the exposures were prior preterm birth. Adjusted odds ratios and 95% confidence intervals were computed using logistic regression. Results. Women who had a previous preterm birth have 63% increased odds of stillbirth in singleton pregnancies and 75% increased odds in twins as compared to those who did not have a pre

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Sapantzoglou, Ioakeim, Maria Giourga, Afroditi Maria Kontopoulou, et al. "Low PAPPA and Its Association with Adverse Pregnancy Outcomes in Twin Pregnancies: A Systematic Review of the Literature and Meta-Analysis." Journal of Clinical Medicine 13, no. 22 (2024): 6637. http://dx.doi.org/10.3390/jcm13226637.

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Background: It is well established in the literature that pregnancy-associated plasma protein-A (PAPP-A) is linked to several adverse pregnancy outcomes, including pre-eclampsia (PE), fetal growth restriction (FGR), and preterm birth (PTB) in singleton pregnancies. However, data regarding such an association in twin pregnancies are lacking. The primary goal of this systematic review and meta-analysis was to assess the potential value of low PAPP-A levels in the prediction of the subsequent development of hypertensive disorders of pregnancy (HDPs), PTB, and small for gestational age (SGA)/FGR f

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Dröge, L., I. Herraìz, H. Zeisler, et al. "Maternal serum sFlt-1/PlGF ratio in twin pregnancies with and without pre-eclampsia in comparison with singleton pregnancies." Ultrasound in Obstetrics & Gynecology 45, no. 3 (2015): 286–93. http://dx.doi.org/10.1002/uog.14760.

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Haque, Roksana, Md Mizanur Rahman, and Khaleda Akhter. "Intrauterine Single Fetal Demise in Twin Pregnancy." Delta Medical College Journal 6, no. 1 (2018): 53–57. http://dx.doi.org/10.3329/dmcj.v6i1.35970.

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Intrauterine demise of one of the twin fetuses during second or third trimester of pregnancy is an uncommon complication. Fetal death of a twin during the first trimester is not an uncommon event and does not appear to impair the development of the second twin. However, fetal death during second or third trimester may increase the risk of IUGR, microcephaly, cerebral encephalomalacia, pre eclampsia, preterm labour, perinatal mortality. We present two cases with single fetal demise. Death of one of the two fetuses occurred at 23 weeks of gestation in the first case and at 33 weeks in the second

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Hassan, Mahmuda, Ferdousi Choudhury, Marium Begum, Hamidur Rahman, and Sayeba Akhter. "Immediate Perinatal Outcome of Neonates with Maternal Hypertensive Disorders in Pregnancy." Journal of Nepal Paediatric Society 33, no. 3 (2013): 190–95. http://dx.doi.org/10.3126/jnps.v33i3.9252.

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Introduction: Hypertensive disorders of pregnancy seem to be one of the major causes of maternal morbidity and mortality leading to 10-15% of maternal deaths especially in the developing world. This study examines the perinatal outcome of neonates with mothers having hypertensive disorder of pregnancy. Materials and Methods: Seventy three mothers and their newborn babies were selected. Mothers with Gestational hypertension, preeclampsia, eclampsia, chronic hypertension, preeclampsia superimposed on chronic hypertension were included. Gestational diabetics (GDM), chronic maternal diseases, infa

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Sundaram, Senthilpriya, and Keerthana Govindaraj. "Fetomaternal outcome in multiple pregnancy." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 10, no. 12 (2021): 4407. http://dx.doi.org/10.18203/2320-1770.ijrcog20214446.

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Background: Multiple pregnancies are more common in recent days than in the past. Increased maternal age at conception due to delayed childbearing trend has resulted in multifetal gestations. Twin gestation imposes greater demand on the maternal physiological system than does singleton pregnancy. The incidence of multifetal gestation has increased mainly because of advanced maternal age and assisted reproductive technology. Multiple pregnancy is considered as high-risk pregnancy as it contributes significantly to adverse maternal and perinatal outcomes.Methods: In this prospective observationa

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Pattanasri, Melinda, Sonia Kua, Stefan Kane, Shaun Brennecke, and Clare Whitehead. "P-027. The prognostic role of maternal angiogenic markers in suspected pre-eclampsia in twin pregnancies." Pregnancy Hypertension 25 (September 2021): e37-e38. http://dx.doi.org/10.1016/j.preghy.2021.07.062.

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D'Antonio, F. "OP11.06: Aspirin for prevention of pre‐eclampsia in twin pregnancies: a systematic review and meta‐analysis." Ultrasound in Obstetrics & Gynecology 62, S1 (2023): 76. http://dx.doi.org/10.1002/uog.26539.

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Vatika, Tiwari, Sinha Deepty, Pradhan Anup, and Narang Saumya. "A Study to Assess Maternal and Fetal Outcome of Obesity in Pregnancy." International Journal of Pharmaceutical and Clinical Research 15, no. 5 (2023): 89–96. https://doi.org/10.5281/zenodo.12547832.

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<strong>Introduction:</strong> India is dealing with a twin nutritional burden of undernutrition and a growing problem of overweight and obesity. Significant prenatal, intrapartum, postpartum, and neonatal problems are recognized to be a danger for mothers who are overweight or obese during pregnancy and childbirth, as determined by rising maternal body mass index (BMI).<strong>Aim and Objectives:</strong> To evaluate the effect of obesity on the maternal and perinatal outcome in pregnancies complicated by obesity. <strong>Material and Methods: </strong>This is a Prospectiv

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Mustafa, H., E. Kalafat, M. Heydari, R. Nunge, and A. Khalil. "OP11.01: Machine learning prediction of gestational hypertension and pre‐eclampsia in twin pregnancies: a population‐based study." Ultrasound in Obstetrics & Gynecology 62, S1 (2023): 74. http://dx.doi.org/10.1002/uog.26534.

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Pradhan, Kumudini, Lina Baru, and Ashish Dharua. "Pregnancy outcome in elderly primigravida." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 8, no. 12 (2019): 4684. http://dx.doi.org/10.18203/2320-1770.ijrcog20195172.

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Background: Incidence of elderly primigravida has increased now days, due to rising education level, effective means of birth control and high carrier goals. The women who conceived in advanced age more than 35 years for first time is defined as elderly primigravida. Indian standard is fixed at more than 30 years by Dutta 2013. These women are high risk for maternal and foetal complication and outcome. The study was done to assess pregnancy outcome in elderly primigravida.Methods: This is a prospective hospital-based study done from October 2016 to November 2018. Women of reproductive age grou

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Hannon, Anne Marie, Triona O’Shea, Claire A. Thompson, et al. "Pregnancy in acromegaly is safe and is associated with improvements in IGF-1 concentrations." European Journal of Endocrinology 180, no. 4 (2019): K21—K29. http://dx.doi.org/10.1530/eje-18-0688.

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Pregnancy is rarely reported in acromegaly. Many patients are diagnosed in later life and younger patients may have subfertility due to hypopituitarism. We present a case series of 17 pregnancies in 12 women with acromegaly. Twelve women with acromegaly who completed pregnancy were identified from centres involved in the Irish Pituitary Study. Eleven women had pituitary macroadenomas and one woman had a microadenoma. Only 5/17 pregnancies had optimal biochemical control of acromegaly preconception, as defined by IGF-1 concentration in the age-related reference level and plasma GH concentration

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Iwo-Amah, Rose Sitonma, Felix Clement C. Wekere, Uduak Ocheche, Peter Abiye Awoyesuku, Faithwin Horsefall, and Elizabeth Bema. "The trend of higher-order multiple gestation in a tertiary hospital in South-South Nigeria." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 13, no. 11 (2024): 3013–17. http://dx.doi.org/10.18203/2320-1770.ijrcog20243151.

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Background: Higher-order multiple (HOM) Gestations are pregnancies with three or more fetuses within the uterus at the same time. The advent of assisted reproductive technology (ART) has caused an increase in its occurrence. Prevalence of naturally occurring HOM births is 1-7 per 10,000 deliveries. HOM are associated with adverse obstetric and perinatal outcomes, when compared with singleton births. In Nigeria, ART is gaining ground, after an initial reluctance. The aim of this study was to highlight the adverse obstetric and perinatal outcomes of HOM pregnancies and births in a tertiary hospi

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Korb, Diane, Thomas Schmitz, Aurélien Seco, et al. "Increased risk of severe maternal morbidity in women with twin pregnancies resulting from oocyte donation." Human Reproduction 35, no. 8 (2020): 1922–32. http://dx.doi.org/10.1093/humrep/deaa108.

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Abstract STUDY QUESTION Is there a difference in the risk of serious maternal complications during pregnancy and the postpartum in twin pregnancies according to mode of conception: natural conception, non-IVF fertility treatment, IVF, ICSI or oocyte donation? SUMMARY ANSWER Women with twin pregnancies after medically assisted reproduction (MAR) had an overall risk of serious maternal complications 30% higher compared with women with natural twin pregnancies, and this association varied according to the MAR procedure; the risk was increased by 50% with IVF using autologous oocytes and by 270% w

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Vijayalaxmi, Davalagi, Chepuri Venkataravikumar, and Shree Shilpa. "The Clinical Study of Twin Pregnancy and its Effect on Maternal and Fetal Outcome." International Journal of Toxicological and Pharmacological Research 12, no. 7 (2022): 216–19. https://doi.org/10.5281/zenodo.11649403.

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<strong>Background: </strong>There has been an unprecedented rise in multiple pregnancy in the last two decades.  An increment of 50% was observed in number of live births from twin deliveries. Naturally 1 out of 80 pregnancies are twin pregnancies, corresponding to 2.6% of all new-borns, the frequency of monozygotic twin births is rather constant worldwide- approximately one set per 250 births, and by large, is independent of race, heredity, age, and parity. <strong>Materials & Methods: </strong>The present prospective study was conducted from 1/1/2019 to 31/12/2019 fo

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Rodríguez, Claudia Martín, Eduardo Martínez Morales, Esther Rubio González, et al. "ANALYSING THE RELATIONSHIP BETWEEN SFLT-1/PLGF RATIO AND PREMATURE BIRTH." Journal of Hypertension 42, Suppl 1 (2024): e315-e316. http://dx.doi.org/10.1097/01.hjh.0001022788.97769.31.

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Objective: To analyse the relationship between sFlt-1/PlGF ratio and the occurrence of premature birth (<37 week) Design and method: An observational, retrospective, cross-sectional study that includes pregnant women who under sFlt-1/PlGF ratio determination since January until September 2022 in a tertiary hospital. Baseline characteristics and data related with the pregnancy, birth and the development of hypertensive disorders of pregnancy (HDP) were included. A multivariate logistic regression was applied to identify risk factors. Results: Out of 109 recruited patients, 104 were analyzed

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Filipecka‐Tyczka, D., A. Kajdy, A. Pokropek, and M. Rabijewski. "P11.09: Relation between uterine arteries pulsatility index and the occurrence of gestational hypertension, pre‐eclampsia and hypotrophy in twin pregnancies." Ultrasound in Obstetrics & Gynecology 54, S1 (2019): 190. http://dx.doi.org/10.1002/uog.20985.

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