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1

Ferreira, Paulo. "EE II 2 1220a39–b6." Revista Archai, no. 20 (2017): 123–40. http://dx.doi.org/10.14195/1984-249x_20_5.

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2

LaMunion, Samuel R., Andrew L. Blythe, Paul R. Hibbing, Andrew S. Kaplan, Brandon J. Clendenin, and Scott E. Crouter. "Use of consumer monitors for estimating energy expenditure in youth." Applied Physiology, Nutrition, and Metabolism 45, no. 2 (2020): 161–68. http://dx.doi.org/10.1139/apnm-2019-0129.

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The purpose of this study was to compare energy expenditure (EE) estimates from 5 consumer physical activity monitors (PAMs) to indirect calorimetry in a sample of youth. Eighty-nine youth (mean (SD); age, 12.3 (3.4) years; 50% female) performed 16 semi-structured activities. Activities were performed in duplicate across 2 visits. Participants wore a Cosmed K4b2(criterion for EE), an Apple Watch 2 (left wrist), Mymo Tracker (right hip), and Misfit Shine 2 devices (right hip; right shoe). Participants were randomized to wear a Samsung Gear Fit 2 or a Fitbit Charge 2 on the right wrist. Oxygen c
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3

Badrov, Mark B., Sophie Lalande, T. Dylan Olver, Neville Suskin, and J. Kevin Shoemaker. "Effects of aging and coronary artery disease on sympathetic neural recruitment strategies during end-inspiratory and end-expiratory apnea." American Journal of Physiology-Heart and Circulatory Physiology 311, no. 4 (2016): H1040—H1050. http://dx.doi.org/10.1152/ajpheart.00334.2016.

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In response to acute physiological stress, the sympathetic nervous system modifies neural outflow through increased firing frequency of lower-threshold axons, recruitment of latent subpopulations of higher-threshold axons, and/or acute modifications of synaptic delays. Aging and coronary artery disease (CAD) often modify efferent muscle sympathetic nerve activity (MSNA). Therefore, we investigated whether CAD ( n = 14; 61 ± 10 yr) and/or healthy aging without CAD (OH; n = 14; 59 ± 9 yr) modified these recruitment strategies that normally are observed in young healthy (YH; n = 14; 25 ± 3 yr) in
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4

Heinitz, Sascha, Alessio Basolo, Paolo Piaggi, Daniele Piomelli, Reiner Jumpertz von Schwartzenberg, and Jonathan Krakoff. "Peripheral Endocannabinoids Associated With Energy Expenditure in Native Americans of Southwestern Heritage." Journal of Clinical Endocrinology & Metabolism 103, no. 3 (2017): 1077–87. http://dx.doi.org/10.1210/jc.2017-02257.

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Abstract Context The endocannabinoids anandamide (AEA) and 2-arachidonoylglycerol (2-AG), as well as the related acylethanolamide oleoylethanolamide (OEA), have been implicated in energy expenditure (EE) regulation and metabolic diseases. Muscle (fat-free mass) and fat (fat mass) are metabolically active compartments and main determinants of EE. Objective To assess whether human muscle, adipose, and plasma endocannabinoids correlate with EE. Design Muscle, adipose, and plasma AEA, 2-AG, and OEA concentrations were measured via liquid chromatography–mass spectrometry. EE was assessed by indirec
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5

Treuth, Margarita S., Anne L. Adolph, and Nancy F. Butte. "Energy expenditure in children predicted from heart rate and activity calibrated against respiration calorimetry." American Journal of Physiology-Endocrinology and Metabolism 275, no. 1 (1998): E12—E18. http://dx.doi.org/10.1152/ajpendo.1998.275.1.e12.

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The purpose of this study was to predict energy expenditure (EE) from heart rate (HR) and activity calibrated against 24-h respiration calorimetry in 20 children. HR, oxygen consumption (V˙o 2), carbon dioxide production (V˙co 2), and EE were measured during rest, sleep, exercise, and over 24 h by room respiration calorimetry on two separate occasions. Activity was monitored by a leg vibration sensor. The calibration day ( day 1) consisted of specified behaviors categorized as inactive (lying, sitting, standing) or active (two bicycle sessions). On the validation day ( day 2), the child select
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6

Nguyen, Dac Minh Tuan, Virgile Lecoultre, Yoshiyuki Sunami, and Yves Schutz. "Assessment of Physical Activity and Energy Expenditure by GPS Combined With Accelerometry in Real-Life Conditions." Journal of Physical Activity and Health 10, no. 6 (2013): 880–88. http://dx.doi.org/10.1123/jpah.10.6.880.

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Background:Physical activity (PA) and related energy expenditure (EE) is often assessed by means of a single technique. Because of inherent limitations, single techniques may not allow for an accurate assessment both PA and related EE. The aim of this study was to develop a model to accurately assess common PA types and durations and thus EE in free-living conditions, combining data from global positioning system (GPS) and 2 accelerometers.Methods:Forty-one volunteers participated in the study. First, a model was developed and adjusted to measured EE with a first group of subjects (Protocol I,
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7

Fong, Cora J., Lyle D. Burgoon, Kurt J. Williams, A. Daniel Jones, Agnes L. Forgacs, and Timothy R. Zacharewski. "Effects of tamoxifen and ethynylestradiol cotreatment on uterine gene expression in immature, ovariectomized mice." Journal of Molecular Endocrinology 45, no. 3 (2010): 161–73. http://dx.doi.org/10.1677/jme-09-0158.

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Tamoxifen (TAM), the primary treatment for estrogen receptor (ER)-positive breast cancer, has been associated with an increased incidence of endometrial cancer in postmenopausal, but not premenopausal women. TAM elicits a partial ER-mediated uterotrophic response in immature rodents when compared with ethynylestradiol (EE), a potent ER agonist. However, cotreatment with 1000 μg/kg TAM antagonizes the uterotrophic effect induced by 30 μg/kg EE. To further investigate the anti-uterotrophic activity of TAM, immature, ovariectomized C57BL/6 mice were treated with a single oral dose of EE, TAM, EE+
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8

Ahn, Jiyun, Min Young Um, Hyunjung Lee, Chang Hwa Jung, Seok Hyun Heo, and Tae Youl Ha. "Eleutheroside E, An Active Component ofEleutherococcus senticosus, Ameliorates Insulin Resistance in Type 2 Diabetic db/db Mice." Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–9. http://dx.doi.org/10.1155/2013/934183.

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Eleutheroside E (EE), a principal component ofEleutherococcus senticosus(ES), has anti-inflammatory and protective effects in ischemia heart. However, it is unknown whether it ameliorates insulin resistance and reduces hyperglycemia in diabetes. This study investigated the effect of EE-containing ES extracts, as well as EE, on hyperglycemia and insulin resistance in db/db mice. EE increased the insulin-provoked glucose uptake in C2C12 myotubes. Moreover, EE improved TNF-α-induced suppression of glucose uptake in 3T3-L1 adipocytes. Five-week-old db/db mice were fed a diet consisting of ES extra
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9

Chang, P. Y., and W. W. Myre. "OS/2 EE Database Manager overview and technical highlights." IBM Systems Journal 27, no. 2 (1988): 105–18. http://dx.doi.org/10.1147/sj.272.0105.

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10

Huddleston, Holly R., Vaughn Barry, and Jennifer L. Caputo. "School Day Energy Expenditure in Elementary School Children." Journal of Physical Activity and Health 13, no. 9 (2016): 1010–12. http://dx.doi.org/10.1123/jpah.2015-0719.

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Background:The purpose was to characterize energy expenditure (EE) during academic subjects and activities during an elementary school day.Methods:Children in 2nd to 4th grades (N = 33) wore the SenseWear Armband (SWA) for 5 school days to measure EE. Teachers’ logs were compared with SWA data to extract information about EE throughout the day. Energy expenditure was also compared among grades.Results:After controlling for body mass, grade level was not a significant predictor of average daily caloric expenditure, F (2, 17.58) = .29, P = .75, ω2 = .05. When comparing activities throughout the
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11

de la Tremblaye, Patricia B., Jody L. Wellcome, Benjamin Wells de Witt, et al. "Rehabilitative Success After Brain Trauma by Augmenting a Subtherapeutic Dose of Environmental Enrichment With Galantamine." Neurorehabilitation and Neural Repair 31, no. 10-11 (2017): 977–85. http://dx.doi.org/10.1177/1545968317739999.

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Background. Environmental enrichment (EE) confers benefits after traumatic brain injury (TBI) when provided daily for > 6 hours, but not 2 or 4 hours, which more accurately reflects the daily amount of clinical rehabilitation. The lack of benefit with sub-therapeutic EE suggests that augmentation with galantamine (GAL), which enhances cognition after TBI, may be indicated to confer benefits. Objective. To test the hypothesis that 2 and 4 hours of EE paired with GAL will provide benefits comparable to 24 hours of EE alone. Moreover, all EE groups will perform better than the standard (STD)-h
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12

Hinojosa-Marqués, Lídia, Manel Monsonet, Thomas R. Kwapil, and Neus Barrantes-Vidal. "The impact of family environment on self-esteem and symptoms in early psychosis." PLOS ONE 16, no. 4 (2021): e0249721. http://dx.doi.org/10.1371/journal.pone.0249721.

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Expressed emotion (EE) and self-esteem (SE) have been implicated in the onset and development of paranoia and positive symptoms of psychosis. However, the impact of EE on patients’ SE and ultimately on symptoms in the early stages of psychosis is still not fully understood. The main objectives of this study were to examine whether: (1) patients’ SE mediated the effect of relatives’ EE on patients’ positive symptoms and paranoia; (2) patients’ perceived EE mediated the effect of relatives’ EE on patients’ SE; (3) patients’ SE mediated between patients’ perceived EE and patients’ symptomatology;
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13

Basu, Samar, Kristell Combe, Rachida Nachat-Kappes, et al. "Impact of enriched environment on tumor growth and adipokines secretion in a mouse model of mammary cancer." Journal of Clinical Oncology 31, no. 15_suppl (2013): e11552-e11552. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.e11552.

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e11552 Background: Enriched environment (EE) by promoting physical activity and social communication reduces development of tumors such as in colon cancer. It seems to act particularly through a decrease of leptin production which linked to breast cancer risk. Thus, the aim of this study was to investigate the effect of EE on the mammary tumor development and to identify the molecular pathways in relation to adipokines secretion. Methods: 3-week-old female C57BL/6 mice were housed in standard environment (SE) or in EE for 9 weeks. A half of EE and SE mice received either EO771 syngeneic cells
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14

Lim, Sun-Young, and Hiramitsu Suzuki. "Dose-Response Effect of Docosahexaenoic Acid Ethyl Ester on Maze Behavior and Brain Fatty Acid Composition in Adult Mice." International Journal for Vitamin and Nutrition Research 72, no. 2 (2002): 77–84. http://dx.doi.org/10.1024/0300-9831.72.2.77.

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The dose-response effect of dietary docosahexaenoic acid (DHA, 22:6 n-3) ethyl ester (EE) on maze-learning ability in mice was studied. Male Crj:CD-1 mice aged three months were fed a) a diet containing 5 g palm oil/100 g diet (control group); b) a diet containing 0.5 g DHA ethyl ester/100 g diet plus 4.5 g palm oil/100g diet (DHA-EE 0.5% group); c) a diet containing 1g DHA ethyl ester/100 g diet plus 4g palm oil/100 g diet (DHA-EE 1% group); d) a diet containing 2 g DHA ethyl ester/100 g diet plus 3 g palm oil/100 g diet (DHA-EE 2% group) for four months. Maze-learning ability was assessed th
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15

Klein, Pamela, Peter Ordentlich, William McCulloch, Scott Cruickshank, Miranda Rees, and Denise Aysel Yardley. "Characterization of the overall survival benefit in ENCORE 301, a randomized placebo-controlled phase II study of exemestane with and without entinostat in ER+ postmenopausal women with metastatic breast cancer." Journal of Clinical Oncology 30, no. 15_suppl (2012): 567. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.567.

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567 Background: Histone deacetylase inhibitors (HDACi) prevent the emergence of drug tolerant clones and sensitize cells to a variety of anti-cancer therapies. We previously reported ENCORE 301, a randomized placebo controlled phase 2 study comparing exemestane with (EE) and without (EP) the HDACi entinostat met its primary endpoint of prolonging progression free survival (PFS) (4.3 months vs 2.3 months) and extending overall survival (OS) benefit (26.9 vs 19.8 months). In order to characterize and better understand the OS benefit, exploratory analyses were conducted. Methods: Hazard ratios (H
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16

Jeong, Deok, Jongsung Lee, Sang Hee Park, et al. "Antiphotoaging and Antimelanogenic Effects of Penthorum chinense Pursh Ethanol Extract due to Antioxidant- and Autophagy-Inducing Properties." Oxidative Medicine and Cellular Longevity 2019 (April 3, 2019): 1–14. http://dx.doi.org/10.1155/2019/9679731.

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Ethnopharmacological Relevance. Penthorum chinense Pursh (Penthoraceae) is a traditional herbal plant that has been used in China for the treatment of jaundice, cholecystitis, edema, and infectious hepatitis. In addition, the Korea Medicinal Plant Dictionary states that Penthorum chinense Pursh can be used to treat contusions and skin bruises by improving blood flow. Recent studies have shown that Penthorum chinense Pursh ethanol extract (Pc-EE) exhibits strong antioxidant effects. In this study, we examined the effects of Pc-EE on UVB-induced or H2O2-induced oxidative stress, as well as its a
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17

Westerterp-Plantenga, Margriet S., Annelies H. C. Goris, Erwin P. Meijer, and Klaas R. Westerterp. "Habitual meal frequency in relation to resting and activity-induced energy expenditure in human subjects: the role of fat-free mass." British Journal of Nutrition 90, no. 3 (2003): 643–49. http://dx.doi.org/10.1079/bjn2003940.

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Habitual meal frequency was assessed as a possible function of components of energy expenditure (EE) in human subjects. Fifty-six subjects participated (four categories differing in body composition): ten older women (fat-free mass (FFM) 42·0 (sd 6·3) kg, aged 59 (sd 2) years, BMI 27·5 (sd 6·9) kg/m2), fifteen younger women (FFM 45·5 (sd 5·2) kg, aged 34 (sd 10) years, BMI 21·9 (sd 2·3) kg/m2), twelve older men (FFM 56·8 (sd 5·9) kg, aged 62 (sd 4) years, BMI 25·7 (sd 3·3) kg/m2) and nineteen younger men (FFM 63·9 (sd 7·5) kg, aged 23·1 (sd 3·9) years, BMI 22·9 (sd 1·8) kg/m2). Measurements co
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18

Lee, Jung Eun, David F. Stodden, and Zan Gao. "Young Children’s Energy Expenditure and Moderate-to-vigorous Physical Activity on Weekdays and Weekends." Journal of Physical Activity and Health 13, no. 9 (2016): 1013–16. http://dx.doi.org/10.1123/jpah.2015-0725.

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Background:Few studies have examined young children’s leisure- and school-based energy expenditure (EE) and moderateto-vigorous physical activity (MVPA). The purpose of this study was to explore children’s estimated EE rates and time spent in MVPA in 3 time segments: at-school, after-school, and weekends.Methods:A total of 187 second and third grade children from 2 elementary schools participated in the study. Accelerometers were used to assess children’s 5-day EE and MVPA. Multiple 2 (Grade) × 2 (Gender) ANOVAs with repeated measures (Time) were conducted to examine the differences in the out
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Sabo, John P., Benjamin Lang, Mabrouk Elgadi, and Fenglei Huang. "Effect of the Hepatitis C Virus Protease Inhibitor Faldaprevir on the Pharmacokinetics of an Oral Contraceptive Containing Ethinylestradiol and Levonorgestrel in Healthy Female Volunteers." Antimicrobial Agents and Chemotherapy 59, no. 1 (2014): 514–19. http://dx.doi.org/10.1128/aac.03589-14.

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ABSTRACTFaldaprevir is a potent hepatitis C virus (HCV) NS3/4A protease inhibitor. Faldaprevir is known to inhibit P-glycoprotein, CYP3A4, and UDP-glucuronosyltransferase 1A1. This study evaluated the effect of steady-state 240 mg faldaprevir on the pharmacokinetics (PK) of an oral contraceptive containing ethinylestradiol (EE) and levonorgestrel (LNG) in healthy premenopausal women. In period 1, subjects received EE/LNG once daily (QD) for 14 days. Blood samples were taken on days 1, 11, and 12, with intensive PK blood sampling for EE and LNG on day 13. In period 2, subjects received EE-LNG Q
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Gundersen, Morten, Guro Austli, Sigrid Løvland, Mari Hansen, Mari Rødseth та Elisabeth Jacobsen. "Lipase Catalyzed Synthesis of Enantiopure Precursors and Derivatives for β-Blockers Practolol, Pindolol and Carteolol". Catalysts 11, № 4 (2021): 503. http://dx.doi.org/10.3390/catal11040503.

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Sustainable methods for producing enantiopure drugs have been developed. Chlorohydrins as building blocks for several β-blockers have been synthesized in high enantiomeric purity by chemo-enzymatic methods. The yield of the chlorohydrins increased by the use of catalytic amount of base. The reason for this was found to be the reduced formation of the dimeric by-products compared to the use of higher concentration of the base. An overall reduction of reagents and reaction time was also obtained compared to our previously reported data of similar compounds. The enantiomers of the chlorohydrin bu
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Eiler, Hugo, Cindy S. Armstrong-Backus, and John D. Smalling. "Effect of electroejactuation on progesterone and Cortisol excretion in bovine semen." American Journal of Veterinary Research 48, no. 3 (1987): 492–95. https://doi.org/10.2460/ajvr.1987.48.03.492.

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SUMMARY Artificial vagina (av) and electroejaculation (ee) are the 2 methods used to obtain semen from bulls. The purpose in the present study was to evaluate these 2 methods of collection when 2 markers, Cortisol and progesterone, were injected iv. During period 1 (control measurement), semen was obtained by ee at 0, 20, 60, 120, and 180 minutes. In period 2, bulls were injected (3 days later) with a mixture of Cortisol (113 mg) and progesterone (100 mg), and then samples were obtained by ee. In period 3, Cortisol and progesterone were injected (3 weeks later), and samples were obtained by av
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22

Vernillo, Gianluca, Aldo Savoldelli, Barbara Pellegrini, and Federico Schena. "Validity of the SenseWear Armband to Assess Energy Expenditure in Graded Walking." Journal of Physical Activity and Health 12, no. 2 (2015): 178–83. http://dx.doi.org/10.1123/jpah.2013-0437.

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Background:Accurate assessments of physical activity and energy expenditure (EE) are needed to advance research on positive and negative graded walking.Purpose:To evaluate the validity of 2 SenseWear Armband monitors (Pro3 and the recently released Mini) during graded walking.Methods:Twenty healthy adults wore both monitors during randomized walking activities on a motorized treadmill at 7 grades (0%, ±5%, ±15%, and ±25%). Estimates of total EE from the monitors were computed using different algorithms and compared with values derived from indirect calorimetry methodology using a 2-way mixed m
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Ferentinos, Panagiotis, Stamatina Douki, Vasiliki Yotsidi, et al. "Family in Crisis: Do Halfway Houses Perform Better Than Families with Expressed Emotion toward Patients with Schizophrenia? A Direct Adjusted Comparison." Healthcare 12, no. 3 (2024): 375. http://dx.doi.org/10.3390/healthcare12030375.

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Expressed emotion (EE) toward patients with schizophrenia is typically reported to be lower in psychiatric halfway houses than in families. This is the first study directly comparing EE between these settings and investigating the pathways mediating EE differences. We included 40 inpatients in halfway houses and 40 outpatients living with their families and recorded 22 psychiatric nurses’ and 56 parents’ EE, respectively, through Five Minutes Speech Samples. Each inpatient was rated by 2–5 nurses and each outpatient by 1–2 parents. As EE ratings had a multilevel structure, generalized linear m
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Whybrow, Stephen, Patrick Ritz, Graham W. Horgan, and R. James Stubbs. "An evaluation of the IDEEA™ activity monitor for estimating energy expenditure." British Journal of Nutrition 109, no. 1 (2012): 173–83. http://dx.doi.org/10.1017/s0007114512000645.

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Objective estimates of activity patterns and energy expenditure (EE) are important for the measurement of energy balance. The Intelligent Device for Energy Expenditure and Activity (IDEEA) can estimate EE from the thirty-five postures and activities it can identify and record. The present study evaluated the IDEEA system's estimation of EE using whole-body indirect calorimetry over 24 h, and in free-living subjects using doubly-labelled water (DLW) over 14 d. EE was calculated from the IDEEA data using calibration values for RMR and EE while sitting and standing, both as estimated by the IDEEA
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Troøyen, Susanne Hansen, та Elisabeth Egholm Jacobsen. "Chemo-Enzymatic Synthesis of Enantiopure β-Antagonist (S)-Betaxolol". Catalysts 12, № 12 (2022): 1645. http://dx.doi.org/10.3390/catal12121645.

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The β-blocker (S)-betaxolol has been synthesized in 99% enantiomeric excess (ee) from the commercially available precursor 4-(2-hydroxyethyl)phenol. The racemic chlorohydrin 1-chloro-3-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)propan-2-ol was esterified with vinyl acetate catalyzed by lipase B from Candida antarctica, which gave the R-chlorhydrin (R)-1-chloro-3-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)propan-2-ol in 99% ee with 38% yield. The enantiomeric excess of the R-chlorohydrin was retained in an amination reaction with isopropylamine in methanol to yield (S)-betaxolol in 99% ee and with 9%
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26

Mineikytė, R., G. Navickaitė, and J. Valaikienė. "Erkinis encefalitas: studentų požiūrio ir turimų žinių analizė." Neurologijos seminarai 22, no. 76 (2018): 118–22. http://dx.doi.org/10.29014/ns.2018.15.

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Įvadas. Nustatyta, kad sergamumas erkiniu encefalitu (EE) Lietuvoje 2016 m. padvigubėjo ir yra vienas didžiausių Europoje. Šio tyrimo tikslas išsiaiškinti ir įvertinti I–IV kursų medicinos studentų požiūrį ir žinias apie EE sergamumą Lietuvoje, riziką susirgti, komplikacijas, gydymą, naudojamas prevencijos priemones ir informacijos apie erkių platinamų ligų sklaidą. Tiriamieji ir tyrimo metodai. Atlikta anoniminė anketinė apklausa, kurioje dalyvavo 404 studentai, besimokantys Vilniaus universiteto Medicinos fakulteto I–IV kursuose (amžius vid. – 20,7 ± 1,56 m., 17–30 m.) Anketą sudarė 21 pusia
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Lindberg, U. B., N. Crona, L. Stigendal, A. C. Teger-Nilsson, and G. Silfverstolpe. "A Comparison between Effects of Estradiol Valerate and Low Dose Ethinyl Estradiol on Haemostasis Parameters." Thrombosis and Haemostasis 61, no. 01 (1989): 065–69. http://dx.doi.org/10.1055/s-0038-1646528.

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SummaryEthinyl estradiol (EE) is still used to some extent as hormonal replacement therapy (HRT) in the climacteric period. As regards oral contraception, it is well known that the induced increase in cardiovascular disease is related to the estrogen component (invariably EE) in a dose-related fashion. Considerably lower doses of EE are needed in HRT compared to oral contraception.To delineate and compare effects of EE and estradiol valerate (E2V) in doses needed in HRT on haemostasis parameters, 24 postmenopausal women were engaged in a study with an open cross-over design. The doses compared
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Chen, Kong Y., and Ming Sun. "Improving energy expenditure estimation by using a triaxial accelerometer." Journal of Applied Physiology 83, no. 6 (1997): 2112–22. http://dx.doi.org/10.1152/jappl.1997.83.6.2112.

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Chen, Kong Y., and Ming Sun. Improving energy expenditure estimation by using a triaxial accelerometer. J. Appl. Physiol. 83(6): 2112–2122, 1997.—In our study of 125 subjects (53 men and 72 women) for two 24-h periods, we validated energy expenditure (EE), estimated by a triaxial accelerometer (Tritrac-R3D), by using a whole-room indirect calorimeter under close-to-normal living conditions. The estimated EE was correlated with the measured total EE for the 2 days ( r = 0.925 and r = 0.855; P < 0.001) and in minute-by-minute EE ( P < 0.01). Resting EE formulated by the Tritrac was found t
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Rico-Barrio, Irantzu, Sara Peñasco, Leire Lekunberri, et al. "Environmental Enrichment Rescues Endocannabinoid-Dependent Synaptic Plasticity Lost in Young Adult Male Mice after Ethanol Exposure during Adolescence." Biomedicines 9, no. 7 (2021): 825. http://dx.doi.org/10.3390/biomedicines9070825.

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Binge drinking (BD) is a serious health concern in adolescents as high ethanol (EtOH) consumption can have cognitive sequelae later in life. Remarkably, an enriched environment (EE) in adulthood significantly recovers memory in mice after adolescent BD, and the endocannabinoid, 2-arachydonoyl-glycerol (2-AG), rescues synaptic plasticity and memory impaired in adult rodents upon adolescent EtOH intake. However, the mechanisms by which EE improves memory are unknown. We investigated this in adolescent male C57BL/6J mice exposed to a drinking in the dark (DID) procedure four days per week for a d
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Dahim, M. A., M. Mosaby, R. El Morabet, et al. "SUPERPAVE design mixture performance evaluation using Epolene modifier for cold semi-arid climatic region of Saudi Arabia." Archives of Materials Science and Engineering 112, no. 2 (2021): 49–54. http://dx.doi.org/10.5604/01.3001.0015.6285.

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Purpose: To evaluate the superpave design performance using Epolene (EE-2) as modifier, since SUPERPAVE design is a modified and sophisticated aspect as compared to previous mix design for asphalt mixtures. This is primarily due to the fact that superpave design mix also takes into consideration properties of materials beside asphalt. Design/methodology/approach: This study was conducted using Epolene (EE-2) as modifier in order to evaluate the performance of SUPERPAVE suitability for construction of roads in Alfaraa campus (King Khalid University) Abha, in Asir Province of Saudi Arabia. Glow
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Klein, Pamela, William McCulloch, Peter Ordentlich, Scott Cruickshank, Miranda Rees, and Denise Aysel Yardley. "Characterization of the overall survival benefit in ENCORE 301, a randomized, placebo-controlled phase II study of exemestane with and without entinostat in ER+ postmenopausal women with metastatic breast cancer." Journal of Clinical Oncology 30, no. 27_suppl (2012): 128. http://dx.doi.org/10.1200/jco.2012.30.27_suppl.128.

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128 Background: Histone deacetylase inhibitors (HDACi) prevent the emergence of drug tolerant clones and sensitize cells to a variety of anti-cancer therapies. We previously reported ENCORE 301, a randomized placebo controlled phase II study comparing exemestane with (EE) and without (EP) the HDACi entinostat met its primary endpoint of prolonging progression free survival (PFS) (4.3 months vs 2.3 months) and extending overall survival (OS) benefit (26.9 vs 19.8 months). In order to characterize and better understand the OS benefit, exploratory analyses were conducted. Methods: Hazard ratios (
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Lee, Hwa Pyoung, Wooram Choi, Ki Woong Kwon, et al. "Inhibitory Effects of Grewia tomentosa Juss. on IgE-Mediated Allergic Reaction and DNCB-Induced Atopic Dermatitis." Plants 11, no. 19 (2022): 2540. http://dx.doi.org/10.3390/plants11192540.

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Grewia tomentosa Juss. is a deciduous shrub that mainly grows in Asia. Despite studies of other Grewia species for treatment of various diseases, Grewia tomentosa Juss. has not been studied as a medicinal herb. This study evaluates the anti-allergic and anti-topic dermatitis activity of Grewia tomentosa Juss. ethanol extract (Gt-EE). The results show that Gt-EE suppressed IgE–antigen-induced β-hexosaminidase release. The mRNA expression of IL-1β, IL-4, IL-5, IL-6, IL-13, TNF-α, MCP-1, and TSLP, which are involved in allergic responses, was inhibited by Gt-EE in IgE-stimulated RBL-2H3 cells. In
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DELPECH, V. C., Z. YIN, J. ABERNETHY, et al. "The impact in the UK of the Central and Eastern European HIV epidemics." Epidemiology and Infection 137, no. 9 (2009): 1266–71. http://dx.doi.org/10.1017/s0950268809002155.

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SUMMARYDespite increasing migration, the impact of HIV epidemics from Central and Eastern Europe (C&EE) on the UK HIV epidemic remains small. C&EE-born adults comprised 1·2% of adults newly diagnosed with HIV in the UK between 2000 and 2007. Most C&EE-born women probably acquired their infection heterosexually in C&EE. In contrast, 59% of C&EE-born men reported sex with men, half of whom probably acquired their infection in the UK. Previously undiagnosed HIV prevalence in C&EE-born sexual-health-clinic attendees was low (2007, 0·5%) as was overall HIV prevalence in C&am
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Kusumaningtyas, Purwanti, Yessica Yessica, Sara Christina Wenda, Amanda Angelica Sopacua, and Geraldo Vincent. "Pembuatan Media Edukasi: Projek Kreatif Kolaboratif Pendidikan Berkelanjutan Bersama Eco Enzyme Nusantara Salatiga." E-Dimas: Jurnal Pengabdian kepada Masyarakat 15, no. 4 (2024): 771–81. https://doi.org/10.26877/e-dimas.v15i4.19027.

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Pengabdian kepada Masyarakat ini diselenggarakan untuk menjawab kebutuhan Komunitas Relawan Eco-Enzyme Nusantara (EEN) Kota Salatiga terhadap ketersediaan media edukasi untuk gerakan pengelolaan sisa bahan organik (BO) menjadi eco-enzyme (BO-EE) dan pemanfaatan eco-enzyme (EE). Projek kreatif kolaboratif untuk pembuatan media edukasi EE diselenggarakan melalui kolaborasi kelas Script Writing dan Lecturer-Student Community Service (LSCS) Prodi S1 Sastra Inggris UKSW, dengan EEN Kota Salatiga. Projek ini menerapkan metode pembelajaran berkelanjutan dalam pendidikan (sustainable learning in educa
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WU, QIANG-SHENG, A. K. SRIVASTAVA, SHUANG WANG, and JIA-XIN ZENG. "Exogenous application of EE-GRSP and changes in citrus rhizosphere properties." Indian Journal of Agricultural Sciences 85, no. 6 (2015): 802–6. http://dx.doi.org/10.56093/ijas.v85i6.49233.

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Mycorrhization-induced secretion of glomalin-related soil protein (GRSP) is known to contribute in improving soil fertility and aggregate stability. But, there is hardly any evidence that exogenous GRSP could produce the similar type of response. The present study was, therefore, carried out to extract easily extractable GRSP (EE-GRSP) from citrus rhizosphere soils and evaluate the response at 1/4, 1/2 and full strength EE-GRSP solutions watered into the rhizosphere of 27-year-old Satsuma mandarin (Citrus unshiu) grafted on the rootstock of Poncirus trifoliata. After ~5 months, exogenous EE-GR
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Kumahara, Hideaki, Hiroaki Tanaka, Philippe Terrier, et al. "Comparison of 2 Accelerometers for Assessing Daily Energy Expenditure in Adults." Journal of Physical Activity and Health 1, no. 3 (2004): 270–80. http://dx.doi.org/10.1123/jpah.1.3.270.

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Background:Daily energy expenditure (EE) assessment plays an important role in clinical strategies for lifestyle-related diseases. The purpose of this study was to compare the performance of 2 activity monitors from different manufacturers to estimate total energy expenditure (TEE) and physical activity related-energy expenditure (PAEE) in daily living conditions.Methods:Sixteen adults stayed in a respiratory chamber for 24 h. The subjects wore 2 accelerometers based on uniaxial (Lifecorder; UNI) and triaxial accelerometry (Tritrac-R3D; TRI).Results:A highly significant correlation was observe
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Haskins, Mark E., Jennifer S. Hicks, and Luciano Centini. "A codified executive education custom client engagement process." International Journal of Educational Management 34, no. 6 (2020): 1035–48. http://dx.doi.org/10.1108/ijem-06-2019-0218.

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PurposeThis article describes the motivations for, and the process of, creating an executive education (EE) custom client engagement service template to foster closer, more effective working relationships between EE custom clients and service providers. The outcome of that endeavor is presented in the form of a robust, final, client engagement template along with a discussion of benefits gained from its use.Design/methodology/approachFrom a case study perspective, this paper chronicles the actual process one leading business school undertook in order to craft a robust EE custom client engageme
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Summers, Benjamin D., Muhiadin Omar, Thomas O. Ronson, Jared Cartwright, Michael Lloyd, and Gideon Grogan. "E. coli cells expressing the Baeyer–Villiger monooxygenase ‘MO14’ (ro03437) from Rhodococcus jostii RHA1 catalyse the gram-scale resolution of a bicyclic ketone in a fermentor." Organic & Biomolecular Chemistry 13, no. 6 (2015): 1897–903. http://dx.doi.org/10.1039/c4ob01441c.

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Gastinger, Steven, Guillaume Nicolas, Anthony Sorel, Hamid Sefati, and Jacques Prioux. "Energy Expenditure Estimate by Heart-Rate Monitor and a Portable Electromagnetic-Coil System." International Journal of Sport Nutrition and Exercise Metabolism 22, no. 2 (2012): 117–30. http://dx.doi.org/10.1123/ijsnem.22.2.117.

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The aim of this article was to compare 2 portable devices (a heart-rate monitor and an electromagnetic-coil system) that evaluate 2 different physiological parameters—heart rate (HR) and ventilation (VE)—with the objective of estimating energy expenditure (EE). The authors set out to prove that VE is a more pertinent setting than HR to estimate EE during light to moderate activities (sitting and standing at rest and walking at 4, 5, and 6 km/hr). Eleven healthy men were recruited to take part in this study (27.6 ± 5.4 yr, 73.7 ± 9.7 kg). The authors determined the relationships between HR and
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Su, Xin, Ge Huang, Lin Wang, et al. "Validation and Comparison of Long-Term Accuracy and Stability of Global Reanalysis and Satellite Retrieval AOD." Remote Sensing 16, no. 17 (2024): 3304. http://dx.doi.org/10.3390/rs16173304.

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Reanalysis and satellite retrieval are two primary approaches for obtaining large-scale and long-term Aerosol Optical Depth (AOD) datasets. This study evaluates and compares the accuracy, long-term stability, and error characteristics of the MERRA-2, MODIS combined Dark Target and Deep Blue (DT&DB), and VIIRS DB AOD products globally and regionally. The results indicate that the MERRA-2 AOD exhibits the highest accuracy with an expected error (EE, ±0.05 ± 20%) of 83.24% and mean absolute error (MAE) of 0.056, maintaining a stability of 0.010 per decade. However, since the MERRA-2 AOD cease
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Ribeyre, Jérôme, Nicole Fellmann, Jean Vernet, et al. "Components and variations in daily energy expenditure of athletic and non-athletic adolescents in free-living conditions." British Journal of Nutrition 84, no. 4 (2000): 531–39. http://dx.doi.org/10.1017/s0007114500001847.

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The objectives of the study were to determine: (1) daily energy expenditure (EE) of athletic and non-athletic adolescents of both sexes in free-living conditions; (2) day-to-day variations in daily EE during 1 week; (3) energy costs of the main activities; and (4) the effect of usual activity on EE during sleep, seated and miscellaneous activities. Fifty adolescents (four groups of eleven to fifteen boys or girls aged 16–19 years) participated in the study. Body composition was measured by the skinfold-thickness method, and VO2max and external mechanical power (EMP) by a direct method (respira
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Kim, Ji Won, Ki Woong Kwon, Mi-Yeon Kim, and Jae Youl Cho. "Potentilla paradoxa Nutt. Ethanol Extract Exhibits Anti-Inflammatory Effects by Suppression of the Src/NF-kB Signaling Pathway." Plants 11, no. 13 (2022): 1750. http://dx.doi.org/10.3390/plants11131750.

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Inflammation is an immune response that protects against harmful stimuli. However, severe inflammation can cause many diseases, such as diabetes, cancer, and arthritis. In this study, we examined the anti-inflammatory efficacy and mechanism of Potentilla paradoxa Nutt. ethanol extract (Pp-EE) as a new strategy for controlling the inflammatory response. Cellular activities and the molecular target of Pp-EE were identified in RAW264.7 cells and HEK293T cells. The effect of Pp-EE was analyzed using the Griess assay, the luciferase assay, reverse transcription-polymerase chain reaction, and Wester
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Cho, Hyeyoung, and Kyoungah Kang. "Effects of Environmental Enrichment on Neurotrophins in an MPTP-Induced Parkinson’s Disease Animal Model: A Randomized Trial." Biological Research For Nursing 22, no. 4 (2020): 506–13. http://dx.doi.org/10.1177/1099800420931183.

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The aim of this study was to investigate the effect of environmental enrichment (EE) on neurotrophin expression in an animal model of Parkinson’s disease (PD). PD was induced via intraperitoneal injection of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Male mice ( N = 42) were randomly divided into 3 groups: control, MPTP + standard condition (SC), and MPTP + EE. The groups were raised separately for 28 days. On Day 21 they received 1 injection (20 mg/kg MPTP or saline for MPTP and control groups, respectively) every 2 hr for a total of 4 injections. Animals were sacrificed 7 days afte
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Blaak, E. E., M. A. van Baak, K. P. Kempen, and W. H. Saris. "Role of alpha- and beta-adrenoceptors in sympathetically mediated thermogenesis." American Journal of Physiology-Endocrinology and Metabolism 264, no. 1 (1993): E11—E17. http://dx.doi.org/10.1152/ajpendo.1993.264.1.e11.

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This study was intended to investigate the role of alpha- and beta-adrenoceptor populations in the sympathetically mediated thermogenesis in healthy lean males. In the first study, the beta 1-, beta 2-, and beta 3-agonist isoprenaline was infused in increasing doses with and without simultaneous infusion of the beta 1-blocker atenolol (Iso and Iso+AT, respectively). There was an increase in whole body energy expenditure (EE) after infusing Iso+AT (P < 0.001) and an almost twofold higher increase after infusion of Iso only (P < 0.001). Stimulation of the beta 2-adrenoceptors by a specific
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Choi, Eunju, Young-Su Yi, Jongsung Lee, et al. "Anti-Apoptotic and Anti-Inflammatory Activities of Edible Fresh Water Algae Prasiola japonica in UVB-Irradiated Skin Keratinocytes." American Journal of Chinese Medicine 47, no. 08 (2019): 1853–68. http://dx.doi.org/10.1142/s0192415x19500940.

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Skin is the outer tissue layer and is a barrier protecting the body from various external stresses. The fresh water green edible algae Prasiola japonica has antiviral, antimicrobial, and anti-inflammatory properties; however, few studies of its effects on skin-protection have been reported. In this study, Prasiola japonica ethanol extract (Pj-EE) was prepared, and its skin-protective properties were investigated in skin keratinocytes. Pj-EE inhibited ROS production in UVB-irradiated HaCaT cells without cytotoxicity. Pj-EE also suppressed the apoptotic death of UVB-irradiated HaCaT cells by dec
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Rangashamaiah, Muddarangaiah Madyavenkatapura, Sarvpreet Singh Ghuman, and Ranjna Cheema. "Association of Melatonin receptor 1A (MTNR1A) gene polymorphism with seasonal suppression of fertility in buffaloes." Buffalo Bulletin 41, no. 4 (2022): 794. http://dx.doi.org/10.56825/bufbu.2022.4143569.

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The polymorphism in Melatonin receptor 1A (MTNR1A) gene and its association with reproductive cyclicity (cyclic, n=51; non-cyclic, n=50) during summer season and age at first calving (<3.5 years, n=38; >3.5 years, n=60) was investigated in buffaloes subjected to blood sampling. Polymerase chain reaction (PCR) of genomic DNA was carried out using three primers viz. 824 bp (primer pair 1), 856 bp (primer pair 2) and 268 bp (primer pair 3) corresponding to exon-II of MTNR1A gene. Restriction fragment length polymorphism was performed using PCR products of primer pair 1 and 2. The digestion
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Conger, Scott A., Stacy N. Scott, Eugene C. Fitzhugh, Dixie L. Thompson, and David R. Bassett. "Validity of Physical Activity Monitors for Estimating Energy Expenditure During Wheelchair Propulsion." Journal of Physical Activity and Health 12, no. 11 (2015): 1520–26. http://dx.doi.org/10.1123/jpah.2014-0376.

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Background:It is unknown if activity monitors can detect the increased energy expenditure (EE) of wheelchair propulsion at different speeds or on different surfaces.Methods:Individuals who used manual wheelchairs (n = 14) performed 5 wheeling activities: on a level surface at 3 speeds, on a rubberized track at 1 fixed speed and on a sidewalk course at a self-selected speed. EE was measured using a portable indirect calorimetry system and estimated by an Actical (AC) worn on the wrist and a SenseWear (SW) activity monitor worn on the upper arm. Repeated-measures ANOVA was used to compare measur
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Savchenko, Ya V., A. S. Goryachev, I. A. Savin, K. Yu Krylov, A. A. Polupan, and T. M. Birg. "Changes in energy expenditures while reducing pressure support as a predictor of successful spontaneous breathing trial." Messenger of ANESTHESIOLOGY AND RESUSCITATION 17, no. 3 (2020): 24–31. http://dx.doi.org/10.21292/2078-5658-2020-17-3-24-31.

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The objective: to assess changes in energy expenditures (EE) when reducing pressure support (PS) as a predictor of the patient’s readiness for transfer to spontaneous breathing. Subjects and methods. The study included 33 patients who had been on mechanical ventilation for at least 7 days. PS reduced from 20 to 4 cmH2O at the interval of 4 cmH2O. At each level, the patient's EE were measured with indirect calorimetry. At the end of the study, spontaneous breathing trial (SBT) was performed. Results. In 22 (67%) patients, at least one episode of a statistically significant increase in EE was ob
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Gao, Zuer, Jiaxin Tian, Qiaoru Zhang, Haoran Sun, Qingkui Jiang, and Tietao Zhang. "Effects of Dietary Protein and Fat Levels on Growth Performance, Nutrient Digestibility, Serum Indexes, and Rectal Fecal Microbiota of Sika Deer (Cervus nippon) Fawns in Early Wintering Period." Animals 15, no. 7 (2025): 908. https://doi.org/10.3390/ani15070908.

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This study examined the effects of dietary crude protein (CP: 18%, 15%) and crude fat (EE: 8%, 4%) levels, and their interactions, on growth performance, nutrient digestibility, serum indices, and rectal fecal microbiota in sika deer fawns during early wintering. A two-month 2 × 2 factorial experiment was conducted using 32 healthy five-month-old male fawns randomly assigned to four groups: P18E8 (18% CP, 8% EE), P18E4 (18% CP, 4% EE), P15E8 (15% CP, 8% EE), and P15E4 (15% CP, 4% EE). The P18E4 group showed the highest total weight gain and average daily gain (p < 0.05), along with greater
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Suleiman, Ghassan, Haider Habeeb Aodah, Shadi Hanandeh, Murat Ergun, Reem Abu Salim, and Deya Qtiashat. "Investigating the Dynamic Creep of Polymer Modified Hot Mix Asphalt." Civil and Environmental Engineering 20, no. 1 (2024): 387–96. http://dx.doi.org/10.2478/cee-2024-0030.

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Abstract Jordan's road network continues to deteriorate as a consequence of the continuous increase in traffic and the absence of adequate maintenance work. The primary objective of this study was to enhance HMA performance by using polymer-modified asphalt mixtures. The polymer modifier known commercially as Eastman (EE-2) was mixed with binder penetration grade (60–70) at a ratio of 12%. In order to investigate the performance of polymer, the dynamic creep, the resilient modulus and the stability-flow tests were performed. Marshall Mix design was utilized to prepare a total of 50 samples, of
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