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Journal articles on the topic 'Effective FSU size'

Author: Grafiati

Published: 4 June 2021

Last updated: 8 February 2022

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1

Adamus-Górka, M., B. Lind, and A. Brahme. "30 Influence of the effective size of the functional subunit (FSU) on rat spinal cord paralysis." Radiotherapy and Oncology 76 (September 2005): S24—S25. http://dx.doi.org/10.1016/s0167-8140(05)81008-4.

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Kyriazi, H. T., G. E. Carvell, J. C. Brumberg, and D. J. Simons. "Quantitative effects of GABA and bicuculline methiodide on receptive field properties of neurons in real and simulated whisker barrels." Journal of Neurophysiology 75, no. 2 (1996): 547–60. http://dx.doi.org/10.1152/jn.1996.75.2.547.

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1. Carbon fiber multibarrel glass microelectrodes were used to record extracellular single-unit activity during microiontophoretic application of gamma-aminobutyric acid (GABA) or bicuculline methiodide (BMI) onto layer IV barrel neurons in the somatosensory cortex of fentanyl-sedated rats. Excitatory and inhibitory aspects of the neurons' receptive fields were quantified with the use of controlled whisker stimuli. The principally activating whisker and one of its immediately adjacent neighbors were deflected alone or in paired combinations involving a condition-test paradigm. 2. Units were di

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3

Kozlenko, L. S., and S. G. Sineva. "Side effects of rifampicin." Kazan medical journal 67, no. 1 (1986): 42–44. http://dx.doi.org/10.17816/kazmj63059.

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Rifampicin (rifadin) has entered therapeutic practice as an effective and relatively mildly toxic antibiotic. Of the side effects of the drug, liver disorders are the most common. Influenza-like syndrome, which develops under intermittent rifampicin therapy, is much rarer. A peculiarity of our case is that the flu-like syndrome of allergic nature occurred in a patient against the background of using glucocorticoid hormones and other desensitizing agents.

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Cui, Wenbin, and Ajith H. Perera. "What do we know about forest fire size distribution, and why is this knowledge useful for forest management?" International Journal of Wildland Fire 17, no. 2 (2008): 234. http://dx.doi.org/10.1071/wf06145.

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Forest fire size distribution (FSD) is one of the suite of indicators of forest fire regimes. It is applied in forest fire management, particularly for planning and evaluating suppression efforts. It is also used in forest management in the context of emulating natural fire disturbances. Given the recent growth in research and applied interest in this topic, we review and synthesise the state of knowledge on FSD, and identify sources of knowledge uncertainties and future research directions. Based on literature, it is common for forest fires to follow the power law probability distribution, pa

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MORIMOTO, Yuki, and Nobuhiro NAKAMURA. "601 Feasibility study on effective utilizing methods of Nachiguro stone powder : Influence of particle size." Proceedings of the Materials and processing conference 2013.21 (2013): _601–1_—_601–3_. http://dx.doi.org/10.1299/jsmemp.2013.21._601-1_.

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6

Shiri, Tinevimbo, Angela Loyse, Lawrence Mwenge, et al. "Addition of Flucytosine to Fluconazole for the Treatment of Cryptococcal Meningitis in Africa: A Multicountry Cost-effectiveness Analysis." Clinical Infectious Diseases 70, no. 1 (2019): 26–29. http://dx.doi.org/10.1093/cid/ciz163.

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Abstract Background Mortality from cryptococcal meningitis remains very high in Africa. In the Advancing Cryptococcal Meningitis Treatment for Africa (ACTA) trial, 2 weeks of fluconazole (FLU) plus flucytosine (5FC) was as effective and less costly than 2 weeks of amphotericin-based regimens. However, many African settings treat with FLU monotherapy, and the cost-effectiveness of adding 5FC to FLU is uncertain. Methods The effectiveness and costs of FLU+5FC were taken from ACTA, which included a costing analysis at the Zambian site. The effectiveness of FLU was derived from cohorts of consecut

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Sansalvador, M. E., and J. M. Brotons. "How environmental certification can affect the value of organizations? The case of Forest Stewardship Council certification." International Forestry Review 22, no. 4 (2020): 531–43. http://dx.doi.org/10.1505/146554820831255506.

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Forest certification appeared in the 1990's as a way to deal with forest deterioration. Currently, however, public opposition can limit its effectiveness. Business policy makers should analyze how Forest Stewardship Council (FSC) certification can affect the value of companies. Yet, the relation between financial performance and forest certification systems is a subject which has not been explored to a great extent, and the measures used for evaluating financial performance in published studies are not based on business valuation. In this study, Spanish companies with FSC certification are val

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FLACH, SERGEJ, OLEG I. KANAKOV, KONSTANTIN G. MISHAGIN, and MIKHAIL V. IVANCHENKO. "q-BREATHERS IN FPU-LATTICES — SCALING AND PROPERTIES FOR LARGE SYSTEMS." International Journal of Modern Physics B 21, no. 23n24 (2007): 3925–32. http://dx.doi.org/10.1142/s0217979207044974.

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Recently q-breathers - time-periodic solutions which localize in the space of normal modes and maximize the energy density for some mode vector q0 - were obtained for finite nonlinear lattices. We scale these solutions to arbitrarily large lattices in various lattice dimensions. We study the scaling consequence for previously obtained analytical estimates of the localization length of q-breathers for β-FPU and α-FPU lattices. The first finding is that the degree of localization depends only on intensive quantities and is size independent. Secondly, a critical wave vector km is identified, whic

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Souza, Anita D., Megha Vagadia, and Mamatha Daivajna. "Tuning magnetic and magnetocaloric properties of Pr0.6Sr0.4MnO3 through size modifications." Journal of Materials Science: Materials in Electronics 32, no. 11 (2021): 14990–5002. http://dx.doi.org/10.1007/s10854-021-06052-9.

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AbstractParticle size as an effective tool for controlling the magnetic and magnetocaloric properties of Pr0.6Sr0.4MnO3 samples has been studied. In the present work, a direct influence of particle size on the magnitude of magnetization and magnetic transition temperature, TC, can be seen. The TC drops from 309 to 242 K, while the saturation magnetization (MS) decreases from 3.6 to 0.5 μB/f.u. as the particle changes from 120 to 9 nm. Concurrently, coercivity (HC) exhibits a drastic rise emphasizing the enhanced surface disorder in the nanoparticles. Another interesting observation is in the m

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10

Margolin, Leon, Jeremy Luchins, Daniel Margolin, Michelle Margolin, and Sanford Lefkowitz. "20-Week Study of Clinical Outcomes of Over-the-Counter COVID-19 Prophylaxis and Treatment." Journal of Evidence-Based Integrative Medicine 26 (January 1, 2021): 2515690X2110261. http://dx.doi.org/10.1177/2515690x211026193.

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Objectives and Setting. As the lethal COVID-19 pandemic enters its second year, the need for effective modalities of alleviation remains urgent. This includes modalities that can readily be used by the public to reduce disease spread and severity. Such preventive measures and early-stage treatments may temper the immediacy of demand for advanced anti-COVID measures (drugs, antibodies, vaccines) and help relieve strain also on other health system resources. Design and Participants. We present results of a clinical study with a multi-component OTC “core formulation” regimen used in a multiply ex

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11

Ferragut, Mariano Jose, Deborah Barry, and Martina Cummins. "Understanding why healthcare workers refuse the flu vaccine." Journal of Infection Prevention 21, no. 3 (2020): 115–18. http://dx.doi.org/10.1177/1757177420908000.

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Background: Vaccination is one of the most effective interventions used to reduce infections. Nonetheless, concerns and misconceptions about vaccines have resulted in an increased rate of refusal of vaccination among healthcare workers (HCWs) and within the general population. Aim/ Objective: To understand the factors that underlie vaccination-refusal. Methods: A questionnaire was given to the HCWs in the inpatient area of an acute London hospital during May 2019. The sample was one of convenience, i.e. the wards where the principle investigator covered. All staff were approached: 306 in total

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Turtle, Cameron J., Laila-Aicha Hanafi, Daniel Li, et al. "CD19 CAR-T Cells Are Highly Effective in Ibrutinib-Refractory Chronic Lymphocytic Leukemia." Blood 128, no. 22 (2016): 56. http://dx.doi.org/10.1182/blood.v128.22.56.56.

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Abstract BACKGROUND: Ibrutinib, a Bruton Tyrosine Kinase (BTK) inhibitor causes partial responses (PR) in a majority of patients (pts) with chronic lymphocytic leukemia (CLL). However, complete responses (CR) are rare and high-risk pts who progress on ibrutinib have short survival. Lymphodepletion chemotherapy followed by infusion of CD19-specific chimeric antigen receptor (CAR)-modified T cells has produced encouraging responses in CLL in phase 1 clinical trials, but the majority of pts in those studies had not previously received or failed ibrutinib. METHODS: We treated 18 adults with CLL wh

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AGARWAL, MANJU, and ARCHANA S. BHADAURIA. "MODELING H1N1 FLU EPIDEMIC WITH CONTACT TRACING AND QUARANTINE." International Journal of Biomathematics 05, no. 05 (2012): 1250038. http://dx.doi.org/10.1142/s1793524511001805.

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A nonlinear mathematical model is proposed and analyzed to study the dynamics of 2009 H1N1 flu epidemic in a homogeneous population with constant immigration of susceptibles. The effect of contact tracing and quarantine (isolation) strategies in reducing the spread of H1N1 flu is incorporated. The model monitors the dynamics of five sub-populations (classes), namely susceptible with high infection risk, susceptible with reduction of infection risk, infective, quarantined and recovered individuals. The model analysis includes the determination of equilibrium points and carrying out their stabil

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Kałucka, Sylwia, and Izabela Grzegorczyk-Karolak. "Barriers Associated with the Uptake Ratio of Seasonal Flu Vaccine and Ways to Improve Influenza Vaccination Coverage among Young Health Care Workers in Poland." Vaccines 9, no. 5 (2021): 530. http://dx.doi.org/10.3390/vaccines9050530.

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Despite not being full-time health care workers, annual flu vaccination is nevertheless an important consideration for medical students. This study examined the reasons for refusing flu vaccination among medical students, a group characterized by low vaccination coverage, despite the fact that the flu vaccine is arguably the most effective way of preventing serious flu complications. A cross-sectional survey was performed of 1313 students at the Medical University of Lodz. The findings indicate that the main sites of vaccination were primary care centers, and main source of information about i

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15

Chen, Juhn-Jie, Ming-Shan Jeng, Chao-Ho Lan, and Yan-Ching Lee. "The Feasibility of Differential Flow Velocity Dividing Working Areas in a Cleanroom." Journal of the IEST 47, no. 2 (2004): 39–47. http://dx.doi.org/10.17764/jiet.47.2.k46157w550228238.

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The possibility of dividing working areas by airflow velocity differences in a cleanroom with fan-filter unit (FFU) systems was investigated. Without physical partitions, the cleanroom area was divided into working and non-working areas defined by the FFU exit flow velocities, which were maintained at constant value in the working areas and reduced in the non-working areas. As uniform micro-sized particles were released from a particle generator in the non-working area, the concentrations of particles in the working area were monitored by a particle counter. The results showed that high downwa

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Barbara, Andrea, Daniele Ignazio La Milia, Marcello Di Pumpo, et al. "Strategies to Increase Flu Vaccination Coverage among Healthcare Workers: A 4 Years Study in a Large Italian Teaching Hospital." Vaccines 8, no. 1 (2020): 85. http://dx.doi.org/10.3390/vaccines8010085.

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Flu vaccination is recommended among healthcare workers (HCWs). The low vaccination coverage registered in our hospital among HCWs called for new engaging approaches to improve flu vaccination coverage. The aim of this study was to evaluate the efficacy of different strategies implemented during the last four years (2015–2019). A quasi-experimental study was conducted, involving almost 4000 HCWs each year. Starting from the 2015–2016 campaign, new evidence-based strategies were progressively implemented. At the end of each campaign, an evaluation of the vaccination coverage rate reached was pe

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Yan, Lijing, Xia Xu, Zhenyu He, et al. "Antidepressant-Like Effects and Cognitive Enhancement of Coadministration of Chaihu Shugan San and Fluoxetine: Dependent on the BDNF-ERK-CREB Signaling Pathway in the Hippocampus and Frontal Cortex." BioMed Research International 2020 (February 25, 2020): 1–12. http://dx.doi.org/10.1155/2020/2794263.

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Background. Fluoxetine (FLU) is the first-line and widely used medication for depression; however, FLU treatment is almost ineffective in 30%-40% of patients with depression. In addition, there are some problems in FLU treatment, such as delayed efficacy, large side effects, and poor tolerance. Chaihu Shugan San (CSS) is a classic and effective antidepressant Chinese herbal medicine that has been used in China for thousands of years. CSS or coadministration of CSS and FLU has become one of the most recommended methods in the treatment of depression in China. However, the specific pathways of C

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18

Cardona, Lyssette, Shafii Mohammed, and Aileen Federico. "Enhancing Employee Influenza Immunization in a Tertiary-Care Healthcare Setting in the Middle East Using Epic Express Lane Workflow." Infection Control & Hospital Epidemiology 41, S1 (2020): s213—s214. http://dx.doi.org/10.1017/ice.2020.757.

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Background: Influenza virus illness affects millions. The virus’s ability to change yearly and its dependence on private manufacturing leads to major challenges immunizing populations. Currently the United States expects to distribute close to 162–168 million doses of influenza vaccine to the market (CDC, October 25, 2019) to immunize the population for the 2019–2020 season. In line with international best practice, our healthcare facility mandated the seasonal influenza vaccine for all employees. We set out to introduce a novel nursing workflow to enhance our Flu Campaign utilizing our Epic S

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Williams, R. A., and P. Andrews. "Purification of the fructose 1,6-bisphosphate-dependent lactate dehydrogenase from Streptococcus uberis and an investigation of its existence in different forms." Biochemical Journal 236, no. 3 (1986): 721–27. http://dx.doi.org/10.1042/bj2360721.

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The fructose 1,6-bisphosphate [Fru(1,6)P2]-dependent lactate dehydrogenase in cells of Streptococcus uberis N.C.D.O. 2039 was purified by a procedure that included chromatography on DEAE-cellulose and Blue Sepharose CL-6B in phosphate buffers. The enzyme appeared to interact with Blue Sepharose through NADH-binding sites. The homogeneous enzyme had catalytic properties that were generally similar to those of other Fru(1,6)P2-dependent lactate dehydrogenases, and it had no catalytic activity in the absence of Fru(1,6)P2. Its existence in different forms, depending on conditions, was investigate

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Kim, Seong, Byung Um, Dong Im, Jin Lee, and Kyeong Oh. "Combined Ball Milling and Ethanol Organosolv Pretreatment to Improve the Enzymatic Digestibility of Three Types of Herbaceous Biomass." Energies 11, no. 9 (2018): 2457. http://dx.doi.org/10.3390/en11092457.

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A combined ball milling and ethanol organosolv process is proposed for the pretreatment of three types of herbaceous biomass, giant miscanthus, corn stover, and wheat straw. The combined pretreatment was effective at both removing lignin and increasing the glucan content. After 120 min pretreatment, the glucan content increased to 63.09%, and 55.89% of the acid-insoluble lignin was removed from the giant miscanthus sample. The removal of cellulose, hemicellulose, and acetyl groups were correlated with the removal of lignin. The pretreatment of corn stover showed the highest removal of cellulos

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21

Zhen, Dong, Zuolu Wang, Haiyang Li, Hao Zhang, Jie Yang, and Fengshou Gu. "An Improved Cyclic Modulation Spectral Analysis Based on the CWT and Its Application on Broken Rotor Bar Fault Diagnosis for Induction Motors." Applied Sciences 9, no. 18 (2019): 3902. http://dx.doi.org/10.3390/app9183902.

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Induction motors (IMs) are widely used in many manufacturing processes and industrial applications. The harsh work environment, long-time enduring, and overloads mean that it is subjected to broken rotor bar (BRB) faults. The vibration signal of IMs with BRB faults consists of the reliable modulation information used for fault diagnosis. Cyclostationary analysis has been found to be effective in identifying and extracting fault feature. The estimators of cyclic modulation spectrum (CMS) and fast spectral correlation (FSC) based on the short-time fourier transform (STFT) have higher cyclic freq

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Minegishi, T., S. Igarashi, K. Nakamura, et al. "Functional expression of the recombinant human FSH receptor." Journal of Endocrinology 141, no. 2 (1994): 369–75. http://dx.doi.org/10.1677/joe.0.1410369.

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Abstract The functional capacity of the recombinant human FSH (hFSH) receptor was tested on the basis of gonadotrophin stimulation of cyclic AMP (cAMP) production by transient transfections of 293 cells and stable transfections of Chinese hamster ovary (CHO) cells. A CHO cell line expressed with the hFSH receptor cDNA covering the entire amino acid coding region revealed the presence of FSH binding site (Kd 6·2 × 10−10 m) on the plasma membrane. Treatment of transfected cells with hFSH induced dose-dependent increases in intracellular cAMP production. These results indicate that the hFSH recep

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Wang, Shuo, Liaojun Zhang, and Guojiang Yin. "Numerical Investigation of the FSI Characteristics in a Tubular Pump." Mathematical Problems in Engineering 2017 (2017): 1–9. http://dx.doi.org/10.1155/2017/7897614.

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Flow condition was simulated in a shaft tubular pump by using the Shear-Stress Transport (SST) k-ω turbulence model with high quality structured grids in design condition. Corresponding structural vibration characteristics were then analyzed based on two-way coupled Fluid-Structure Interaction (FSI) method. Fluid results showed that flow in the outlet flow passage was a combination of the axial flow and circumferential rotation motion. Time and frequency domain analysis of pressure pulsation of typical measure points indicated that larger pulsation amplitudes appeared in the tip of the blades

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Thomas H, Brannagan III, Khosro Farhad, Inna Kleyman, Megan Leitch, Rebecca Traub, and Christina Ulane. "Existing and Emerging Approaches to Treating Chronic Inflammatory Demyelinating Polyneuropathy." US Neurology 15, no. 1 (2019): 33. http://dx.doi.org/10.17925/usn.2019.15.1.33.

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Chronic inflammatory demyelinating polyneuropathy (CIDP) is a rare disabling disease with an incompletely understood autoimmune etiology. Differentiating the condition from other neurological diseases can be challenging and appropriate treatment is often delayed. Intravenous immunoglobulin (IVIg), plasmapheresis, corticosteroids and subcutaneous immunoglobulin (SCIg) have all been demonstrated to be beneficial in placebo-controlled, randomized clinical trials. Corticosteroids, including methylprednisolone and dexamethasone are effective and frequently used in CIDP but their long-term use is li

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Feng, Caixia, Yongqiang Kang, Lijuan Dong, and Lihong Wang. "High-Gain SIR Dual-Band Antenna Based on CSRR-Enhanced SIW for 2.4/5.2/5.8 GHz WLAN." International Journal of Antennas and Propagation 2020 (July 29, 2020): 1–10. http://dx.doi.org/10.1155/2020/8725192.

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This paper presents a dual-band step impedance resonator (SIR) antenna based on metamaterial-inspired periodic structure of coupled complementary split-ring resonators substrate-integrated waveguide (CSRR-SIW). The antenna supports wireless local area networks (WLAN) bands at 2.4/5.2/5.8 GHz. The CSRRs and two branches of the SIR element are etched on the top and bottom metal surfaces of the substrate. The SIR element produces a fundamental frequency f1 at 2.4 GHz and a second harmonic frequency fs2 at 5.7 GHz. Meanwhile, the CSRRs produces a resonant frequency at high-frequency band around 5.

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Filipi, Mary L., Jill Beavin, Raquel T. Brillante, et al. "Nurses’ Perspective on Approaches to Limit Flu-Like Symptoms During Interferon Therapy for Multiple Sclerosis." International Journal of MS Care 16, no. 1 (2014): 55–60. http://dx.doi.org/10.7224/1537-2073.2013-006.

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Background: Several interferon beta (IFNβ) formulations are approved for first-line use as disease-modifying therapies to treat patients with multiple sclerosis (MS). Systemic post-injection reactions, often termed flu-like symptoms (FLS), occur in approximately half of all patients treated with IFNβs and can affect adherence to therapy. These symptoms, which include pyrexia, chills, malaise, myalgia, and headaches, usually resolve within 24 hours or persist intermittently following each injection. Because FLS, which usually occur early in the treatment course and diminish over time, are a pri

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Masoumi, Maryam, Javad Balasi, Seyed Mahdi Aghamiri, et al. "Side effects of methotrexate therapy in patients with rheumatoid arthritis." Immunopathologia Persa 7, no. 2 (2021): e38-e38. http://dx.doi.org/10.34172/ipp.2021.38.

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Introduction: Methotrexate is widely used as the most common disease-modifying anti-rheumatoid drug (DMARD) and is known as the first line treatment for rheumatoid arthritis (RA). Objectives: To assess the side effects of methotrexate in Iranian patients with RA and to compare them with the known side effects from previous studies. Patients and Methods: We conducted a cross-sectional study of 300 patients who fulfilled the EULAR 2010 criteria of RA. The following data were recruited from patients’ profiles; age, body mass index (BMI), duration of treatment with methotrexate, initiating dose, m

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Spinewine, Anne, Catherine Pétein, Perrine Evrard, et al. "Attitudes towards COVID-19 Vaccination among Hospital Staff—Understanding What Matters to Hesitant People." Vaccines 9, no. 5 (2021): 469. http://dx.doi.org/10.3390/vaccines9050469.

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Hospital staff are a priority target group in the European COVID-19 vaccination strategy. Measuring the extent of COVID-19 vaccination hesitancy and understanding the reasons behind it are essential to be able to tailor effective communication campaigns. Using the Health Belief Model (HBM) as a theoretical framework, a survey was conducted among staff members of a Belgian three-site hospital center between 6 and 20 January 2021. Multivariable logistic ordinal regression was performed to assess determinants of the attitude towards COVID-19 vaccination. Reasons for and against COVID-19 vaccinati

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Espevik, T., M. Brockhaus, H. Loetscher, U. Nonstad, and R. Shalaby. "Characterization of binding and biological effects of monoclonal antibodies against a human tumor necrosis factor receptor." Journal of Experimental Medicine 171, no. 2 (1990): 415–26. http://dx.doi.org/10.1084/jem.171.2.415.

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Three different antibodies against a human TNF receptor (htr-1, htr-5, and htr-9) have been examined for their binding pattern to U937 cells and ability to mimic TNF-alpha activity in U937 cells, Fs4 fibroblasts, and human endothelial cells. Flow cytometric analysis revealed that htr-5 and htr-9 bound specifically to a TNF receptor on U937 cells that could be blocked by pretreatment with rTNF-alpha. Pretreatment of U937 cells with rTNF-beta blocked the binding of htr-9, but to a lesser extent htr-5 binding. Pretreatment with htr-5 inhibited the binding of htr-9 to U937 cells while pretreatment

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Remm, Kalle. "Selecting site characteristics at different spatial and thematic scales for shrubby cinquefoil (Potentilla fruticosa L.) distribution mapping." Forestry Studies 64, no. 1 (2016): 17–38. http://dx.doi.org/10.1515/fsmu-2016-0002.

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Abstract The largest natural population of shrubby cinquefoil (Potentilla fruticosa) in the Baltic States was observed in the field to reveal the scale-dependent explanatory value of site characteristics for subsequent spatial distribution modelling of the species. About 700 km was crossed during field observations in 2008–2014. Thinning of the raw field records to ensure a distance of at least 50 metres between each point yielded 1459 presences and 7327 absences. These occurrence data were related to present and historical land cover, soil, elevation, human population density, the proportion

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Castro, J. E., J. D. Sandoval-Sus, J. Melo-Cardenas, et al. "Phase I study of intranodal direct injection of adenovirus encoding recombinant CD40-ligand (Ad-ISF35) in patients with chronic lymphocytic leukemia." Journal of Clinical Oncology 27, no. 15_suppl (2009): 3003. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.3003.

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3003 Background: Transduction of chronic lymphocytic leukemia (CLL) cells with replication-defective adenovirus (Ad) encoding a genetically engineered, membrane-stablized CD154 (ISF35) converts transduced, and “bystander” non-transduced, CLL cells into proficient antigen presenting cells that can induce immunity against autologous leukemia cells. Preclinical studies demonstrated that direct injection of Ad-ISF35 into lymphoma nodules can induce potent anti-lymphoma immune responses in test animals, capable of eradicating lethal tumors at distal sites and protect against recurrent disease upon

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Bruchwald, Arkadiusz, Elżbieta Dmyterko, and Radomir Balazy. "Risk model of tree stand damage by winds and its evaluation based on damage caused by cyclone “Xaver”." Forest Systems 27, no. 2 (2018): e014. http://dx.doi.org/10.5424/fs/2018272-11731.

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Aim of study: To develop and evaluate the forest’s wind-risk model, dedicated for stand damage level.Area of study: Model was tested in the northeastern Poland.Material and methods: A risk model referring to the damage of forest stands by wind specifies, for every stand in a selected forest district, the risk factor within the range of 0 to 3. The higher value of the factor, the greater risk of damage, if wind occurs. The model was based on 11 features: average size of a tree stand, mean diameter breast high in the specified features’ ratio, species composition, degree of stand density, age of

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Noor, Aijaz Ul, and Ruqaya Aziz. "Plants metabolites as a prospective approach against the COVID-19." International Journal of Basic & Clinical Pharmacology 10, no. 4 (2021): 453. http://dx.doi.org/10.18203/2319-2003.ijbcp20211032.

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The Coronavirus disease 2019 (COVID-19) caused by an RNA virus SARS-CoV-2 is an emerging global health pandemic. With currently no approved treatment or prophylaxis, the SARS-CoV-2 is rapidly transmitted via touch, droplets, and fomites. In most affected patients, the disease will have mild flu-like symptoms (fever, dry cough, and difficulty in breathing) and in selected patients may cause severe complications such as progressive pneumonia, acute respiratory distress syndrome, and organ failure due to hyper-inflammation and cytokine storm syndrome. Understanding the pathogenesis of the disease

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Weiss, Andrea, Xianting Ding, Judy R. van Beijnum, et al. "Rapid optimization of drug combinations for the optimal angiostatic treatment of cancer." Angiogenesis 18, no. 3 (2015): 233–44. http://dx.doi.org/10.1007/s10456-015-9462-9.

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Abstract Drug combinations can improve angiostatic cancer treatment efficacy and enable the reduction of side effects and drug resistance. Combining drugs is non-trivial due to the high number of possibilities. We applied a feedback system control (FSC) technique with a population-based stochastic search algorithm to navigate through the large parametric space of nine angiostatic drugs at four concentrations to identify optimal low-dose drug combinations. This implied an iterative approach of in vitro testing of endothelial cell viability and algorithm-based analysis. The optimal synergistic d

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Morbioli, Laura, and Fabio Lugoboni. "High-dose benzodiazepine dependence among health-care professionals: A neglected phenomenon." Medicine, Science and the Law 61, no. 1_suppl (2021): 42–45. http://dx.doi.org/10.1177/0025802420928650.

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Chronic use of benzodiazepines (BDZs) is a widespread phenomenon which can lead to side effects such as tolerance, dependence and cognitive impairment, as well as resulting in accidents at work. High-dose BDZ dependence (HD-BDZ) is little studied, and it is mainly attributed to major psychiatric disorders and polydrug abuse. To date, few studies have investigated HD-BDZ among active workers, with none among health-care professionals (HPs). Tapering from high doses of BDZs can cause severe withdrawal symptoms, including seizures. The Addiction Unit of the University Hospital in Verona uses a pr

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Zhu, Xueyong, Yong-Hui Guo, Tao Jiang, et al. "A Unique and Conserved Neutralization Epitope in H5N1 Influenza Viruses Identified by an Antibody against the A/Goose/Guangdong/1/96 Hemagglutinin." Journal of Virology 87, no. 23 (2013): 12619–35. http://dx.doi.org/10.1128/jvi.01577-13.

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Despite substantial efforts to control and contain H5N1 influenza viruses, bird flu viruses continue to spread and evolve. Neutralizing antibodies against conserved epitopes on the viral hemagglutinin (HA) could confer immunity to the diverse H5N1 virus strains and provide information for effective vaccine design. Here, we report the characterization of a broadly neutralizing murine monoclonal antibody, H5M9, to most H5N1 clades and subclades that was elicited by immunization with viral HA of A/Goose/Guangdong/1/96 (H5N1), the immediate precursor of the current dominant strains of H5N1 viruses

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Pickernell, David, Paul Jones, Gary Packham, Brychan Thomas, Gareth White, and Robert Willis. "E-commerce trading activity and the SME sector: an FSB perspective." Journal of Small Business and Enterprise Development 20, no. 4 (2013): 866–88. http://dx.doi.org/10.1108/jsbed-06-2012-0074.

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Purpose – This study aims to examine e-commerce within UK small and medium sized enterprises (SMEs). More specifically, it seeks to explore associations between e-commerce and internal and external antecedents including trading behaviour, owner/manager characteristics, innovation, public sector involvement, business advice and finance sources. Design/methodology/approach – An 8,500+ sample derived from the 2008 UK Federation of Small Businesses survey was utilised. An OLS regression equation was generated where the percentage of sales made using e-commerce constituted the dependent variable. I

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Cunliffe, K. V., A. C. Vecchies, E. S. Jones, et al. "Assessment of gene flow using tetraploid genotypes of perennial ryegrass (Lolium perenne L.)." Australian Journal of Agricultural Research 55, no. 4 (2004): 389. http://dx.doi.org/10.1071/ar03156.

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Ryegrass species are among the most important species in sown pastures, turf settings, and weed populations worldwide. Perennial ryegrass (Lolium perenne L.) is an outcrossing, wind-pollinated grass. Recent research has demonstrated the feasibility of developing transgenic perennial ryegrass varieties. In order to model the consequences of gene flow from transgenic grass genotypes in a field situation, the model non-transgenic trait of fertility among autotetraploid genotypes was chosen. Gene flow over distance and direction from a donor plot to surrounding sexually compatible recipient plants

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Liang, Sharolynne Xiao Tong, Ling Shing Wong, Anto Cordelia Tanislaus Antony Dhanapal, Prakash Balu, and Sinouvassane Djearamane. "THERAPEUTIC APPLICATIONS OF Spirulina AGAINST HUMAN PATHOGENIC VIRUSES." Journal of Experimental Biology and Agricultural Sciences 9, Spl-1- GCSGD_2020 (2021): S38—S42. http://dx.doi.org/10.18006/2021.9(spl-1-gcsgd_2020).s38.s42.

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Viruses can spread worldwide and the early detection of emerging infectious diseases and outbreaks in humans and animals is important for effective surveillance and prevention. Viruses such as human immunodeficiency virus (HIV), swine flu, and influenza virus are some of the viruses that spread diseases worldwide. However, the non-availability of effective antiviral drugs and the drug-resistance among the virus and host have become the major problems in controlling viral infections. The natural products from microalgae can be an alternative therapeutic agent to control viral infections in huma

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Alawneh, Issa, Hamza Al-Sayeh, Mahdi Zaid, Maysa Alawneh, and Hossam Al-Tatari. "Knowledge and Attitudes Regarding Seasonal Influenza and Influenza Vaccination among Patients and Their Companions in North Palestine Hospitals." Advances in Public Health 2021 (September 15, 2021): 1–5. http://dx.doi.org/10.1155/2021/3611846.

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Background. Seasonal influenza is a common highly infectious disease that can affect the upper and lower airway in children and adults mainly in wintertime which is caused by many different influenza viruses and, in some cases, may cause serious complications such as pneumonia. We conducted this study to assess the knowledge and attitudes among patients and their companions in North Palestine hospitals regarding seasonal influenza and influenza vaccination and factors influencing the uptake of this vaccine so that we can identify gaps in their knowledge and give feedback to health authorities

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Rosenfeld, Lindsay E., Juliana FW Cohen, Mary T. Gorski, et al. "How do we actually put smarter snacks in schools? NOURISH (Nutrition Opportunities to Understand Reforms Involving Student Health) conversations with food-service directors." Public Health Nutrition 20, no. 3 (2016): 556–64. http://dx.doi.org/10.1017/s1368980016002044.

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AbstractObjectiveIn autumn 2012, Massachusetts schools implemented comprehensive competitive food and beverage standards similar to the US Department of Agriculture’s Smart Snacks in School standards. We explored major themes raised by food-service directors (FSD) regarding their school-district-wide implementation of the standards.DesignFor this qualitative study, part of a larger mixed-methods study, compliance was measured via direct observation of foods and beverages during school site visits in spring 2013 and 2014, calculated to ascertain the percentage of compliant products available to

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Danylesko, Ivetta, Rina Sareli, Nira Bloom-Varda, et al. "The Use Of Tevagrastim (Biosimilar Filgrastim XMO2) For Hematopoietic Stem Cell Mobilization In HLA Matched Sibling Donors For Allogeneic Stem Cell Transplantation To AML/MDS Patients." Blood 122, no. 21 (2013): 3275. http://dx.doi.org/10.1182/blood.v122.21.3275.3275.

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Abstract Introduction Human recombinant G-CSF Filgrastim (Neupogen) has been widely used for the mobilization of CD34+ hematopoietic stem cells (HSC) from healthy donors. The experience with biosimilar G-CSF agents is limited and the only publication, to our knowledge, is the recent study by Schmitt M and co-authors (BMT 2013; 48, 922–925). This study involved 11donors and pts with various disease categories. The Biosimilar G-CSF was found to be comparable in efficacy and safety to Neupogen. Developing new cost effective mobilizing reagents if important. We, therefore, initiated a prospective

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Chan, W. K., and C. H. Tan. "FSH-induced aromatase activity in porcine granulosa cells: non-competitive inhibition by non-aromatizable androgens." Journal of Endocrinology 108, no. 3 (1986): 335–41. http://dx.doi.org/10.1677/joe.0.1080335.

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ABSTRACT The aim of this study was to examine the inhibitory effect of the non-aromatizable androgens on FSH-stimulated aromatase activity in porcine granulosa cells. The cells were isolated from medium-sized follicles (4–6 mm) of prepubertal pigs, and cultured under chemically defined conditions in the presence of FSH (1 μg/ml, NIADDK-oFSH-S13) with and without the androgens for an initial 48-h induction period. Subsequently, the spent medium was replaced with fresh medium containing only testosterone as substrate and the cells were reincubated for a further 6 h. The conversion of this steroi

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Swarnalekha, Nivedya, David Schreiner, Ludivine C. Litzler, et al. "T resident helper cells promote humoral responses in the lung." Science Immunology 6, no. 55 (2021): eabb6808. http://dx.doi.org/10.1126/sciimmunol.abb6808.

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Influenza is a deadly and costly infectious disease, even during flu seasons when an effective vaccine has been developed. To improve vaccines against respiratory viruses, a better understanding of the immune response at the site of infection is crucial. After influenza infection, clonally expanded T cells take up permanent residence in the lung, poised to rapidly respond to subsequent infection. Here, we characterized the dynamics and transcriptional regulation of lung-resident CD4+ T cells during influenza infection and identified a long-lived, Bcl6-dependent population that we have termed T

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Deisher, Theresa, Arya Ashok, Peter Jarzyna, et al. "Receptor-triggered lymphocyte apoptosis PC to replace Cy/Flu PC for CART." Journal of Clinical Oncology 37, no. 15_suppl (2019): e14011-e14011. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e14011.

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e14011 Background: Chimeric antigen receptor T-cell (CAR-T) therapy is a relatively novel regimen for the treatment of acute lymphoblastic leukemia that has already shown promising results. Two FDA-approved CAR-T therapies, Kymriah and Yescarta have an 80% success rate in sending patients into remission. However, both of these treatments require preconditioning (PC) with chemotherapy to ensure CarT expansion and engraftment. Chemotherapy severely compromises patient’s immune-system, a further economic burden up to $70K per patient due to hospitalization, and fuels side effects of CAR-T therapy

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Siakantaris, Marina P., Marie-Christine Kyrtsonis, Tatiana Tzenou, et al. "Interferon Alpha-2B (IFN-a) Is an Effective Agent for the Treatment of Primary Cutaneous T- and B-Cell Lymphoma." Blood 104, no. 11 (2004): 2643. http://dx.doi.org/10.1182/blood.v104.11.2643.2643.

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Abstract Primary cutaneous lymphoma comprise a wide range of rare diseases of which the commonest T- cell subtypes include mycosis fungoides (MF), Sezary syndrome (SS) and peripheral T-cell lymphoma (PTCL) while follicle center cell lymphoma (FCL), diffuse large B-cell lymphoma (DLBL) and extranodal marginal zone B-cell lymphoma (MZL) represent the B-cell subtypes. The behavior of these diseases is different from nodal NHL and it has been shown that IFN-a can produce long-lasting remissions in early stages MF. On the contrary, there are no reports on the efficacy of IFN- a for primary cutaneou

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Dzhagityan, E. "Financial Stability Board: Is Its Institutionalization a Reality?" World Economy and International Relations 59, no. 11 (2015): 78–90. http://dx.doi.org/10.20542/0131-2227-2015-59-11-78-90.

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The article deals with the evolution of the Financial Stability Board (FSB) into a full-scale and sound authority of international banking regulation. Founded in 1999 as the Financial Stability Forum, the FSB has become an international body in 2009 overseeing the international financial regulation reform, also known as Basel III. Nonetheless, FSB’s responsibilities and competence are still limited to the annual determination of global systemically important banks (G-SIBs) and the development of the reform strategies for G-20 consideration. FSB has already proved to be a credible coordinator o

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Churojana, Anchalee, Laksanawadee Mahiwan, Dittapong Songsaeng, Rujimas Khumtong, and Saowanee Homsud. "Predictive Factors for Successful Percutaneous Sclerotherapy of Venous and Lymphatic Malformations." ASEAN Journal of Radiology 19, no. 1 (2013): 29–42. http://dx.doi.org/10.46475/aseanjr.v19i1.20.

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Objectives: To determine the predictive factors for good response outcome of venous (VMs) and lymphatic malformations (LMs) by percutaneous sclerosing therapy and to compare the complications associated with bleomycin versus alcohol treatment. Methods: A retrospective analysis of 225 patients with lymphatic and venous malformation who had treated by percutaneous sclerotherapy using alcohol and/or bleomycin was performed The treatment outcome was graded from 0-3, in orderly of clinical responsiveness by using visual assessment of changing in size and subjective improvement of symptoms. Pr

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Fauble, Veena Devi Salem, James L. Slack, William Hogan, et al. "Allogeniec Stem Cell Transplantation for Primary and Post ET/PV Myelofibrosis At Mayo Clinic: A Retrospective Review Across a Geographically Diverse 3 Site Cancer Center." Blood 120, no. 21 (2012): 2850. http://dx.doi.org/10.1182/blood.v120.21.2850.2850.

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Abstract Abstract 2850 Myelofibrosis (MF), both primary myelofibrosis (PMF) and post essential thrombocytosis/polycythemia vera myelofibrosis (post ET/PV-MF), are chronic myeloproliferative neoplasms characterized by a progressive clinical course that leads to shortened survival. The heterogeneous nature of MF lends itself to a variable clinical course that commonly includes hepatosplenomegaly, constitutional symptoms, and progressive cytopenias. Medical therapy for myelofibrosis has been effective in palliation of common symptoms related to anemia, splenomegaly but allogeneic stem cell transp

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Risitano, Antonio M., Carmine Selleri, Bianca Serio, et al. "Subcutaneous Alemtuzumab Is Safe and Effective for Treatment of Global or Single-Lineage Immune-Mediated Marrow Failure: A Pilot Study." Blood 110, no. 11 (2007): 1692. http://dx.doi.org/10.1182/blood.v110.11.1692.1692.

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Abstract Acquired marrow failure syndromes may globally affect all hematopoietic lineages, as in severe aplastic anemia (SAA), or may selectively involve single lineages, as in pure red cell aplasia (PRCA) or in agranulocytosis (AGR). All these conditions share a cellular immune-mediated pathophysiology, which is supported by many experimental data; thus, various immunosuppressive (IS) strategies have been exploited. Alemtuzumab (MabCampath®) (ALE) is a lympholytic MoAb with strong and prolonged IS activity, more reliable than ATG or ALG as for activity, dosing and commercial availability. Her

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