Relevant bibliographies by topics / Effects of a ketone caffeine supplement

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Academic literature on the topic 'Effects of a ketone caffeine supplement'

Author: Grafiati
Published: 4 June 2021
Last updated: 15 February 2022

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Journal articles on the topic "Effects of a ketone caffeine supplement"

1

Da Costa, D., V. Bangalee, K. Subban, and R. Naidoo. "Ketone body supplement label claims: what supplement has been supplemented?" South African Journal of Sports Medicine 31, no. 1 (October 3, 2019): 1–2. http://dx.doi.org/10.17159/2078-516x/2019/v31i1a6369.

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Background: There is a keen interest in performance-enhancing supplementation and the associated benefits, despite reports of incorrect label claims made by manufacturers and the questionable efficacy of the supplements. The use of ketone body supplements as a source of fuel during exercise and sporting performance, in particular, is of interest to sportspeople. By increasing blood ketone body levels, with an accompanying decrease in blood glucose, may indicate a state of nutritional ketosis, whereby the body no longer relies on glucose metabolism but rather the metabolism of ketone bodies. This could be beneficial for long, slow steady-state endurance exercise. Discussion: There are numerous ketone body supplements on the market manufactured in South Africa and internationally. However, unlike medicines, the sports supplementation industry is poorly regulated. Furthermore, ketone body supplementation with regard to its effects on improving exercise and athletic performance is still unconvincing. Conclusion: Within the ever-changing sports supplementation industry, ketone body supplements are being used despite controversies regarding the accuracy and scientific merit of label claims. The ingredients and their quantities, as well as the performance benefits, need to be objectively validated.
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2

Whalley, Peter J., Chey G. Dearing, and Carl D. Paton. "The Effects of Different Forms of Caffeine Supplement on 5-km Running Performance." International Journal of Sports Physiology and Performance 15, no. 3 (March 1, 2020): 390–94. http://dx.doi.org/10.1123/ijspp.2019-0287.

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Purpose: Caffeine is frequently used by athletes as an ergogenic aid. Various alternate forms of caffeine administration are available, which may produce different effects. This investigation compares the effects of different forms of caffeine supplementation on 5-km running performance, and the relationship between athlete ability and degree of enhancement attained. Methods: Fourteen amateur runners completed a series of self-paced outdoor time trials following unknown ingestion of a placebo (P) or one of 3 alternate forms of caffeine supplement. Trials were randomized in a crossover design with caffeine (approximately 3–4.5 mg·kg−1) administered 15 minutes before each trial via chewing gum (CG), dissolvable mouth strips (CS), or tablet (CT). Results: Compared with P, all caffeine supplements led to worthwhile enhancements in running performance with a mean (±95% confidence limit) overall effect across all supplements of 1.4% ± 0.9%. Individual caffeine treatment effects (CG = 0.9% ± 1.4%, CS = 1.2% ± 1.0%, and CT = 2.0% ± 1.1%) were not significantly different (P > .05) from each other; however, CT trials produced the largest gain and was significantly different (P = .02) compared with P. There was no significant difference in heart rate or rate of perceived exertion across the performance trials. The magnitude of caffeine enhancement was also strongly correlated (r = .87) with no-treatment performance time. Conclusions: The findings showed that irrespective of delivery form, moderate dose of caffeine supplementation produces worthwhile gains in 5-km running performance compared with a P. Furthermore, the magnitude of caffeine enhancement is highly individualized, but it appears related to athlete performance ability.
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Kwon, Sangoh, Minseok Yoon, Jaekwang Lee, Kwang-Deog Moon, Dohyeon Kim, Seon-Bong Kim, and Suengmok Cho. "A Standardized Phlorotannin Supplement Attenuates Caffeine-Induced Sleep Disruption in Mice." Nutrients 11, no. 3 (March 6, 2019): 556. http://dx.doi.org/10.3390/nu11030556.

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In our previous studies, a standardized phlorotannin (brown seaweed polyphenol) supplement (PS) exhibited sleep-promoting effects via type A γ-aminobutyric acid-benzodiazepine receptors in mice. In addition, in human clinical trials, it decreased wake after sleep onset in adults with sleep disturbance. In this follow-up study, we investigated whether PS attenuates caffeine-induced sleep disruption in mice. The effects of PS were evaluated in a caffeine model by analyzing sleep architecture based on electroencephalogram and electromyogram findings, and were compared with the effects of a well-known sedative-hypnotic drug zolpidem (ZPD). As expected, oral administration of caffeine (25 mg/kg) significantly increased sleep latency and decreased the amount of non-rapid eye movement sleep (NREMS). In the caffeine + PS and caffeine + ZPD groups, PS (500 mg/kg) attenuated caffeine-induced sleep disruption, and its effects were comparable with those of ZPD (10 mg/kg). In particular, PS inhibited the arousal effects of caffeine without change in delta activity during NREMS, whereas ZPD produced a decrease in the delta activity. Considering global trends in coffee and energy drink consumption, our finding suggest that PS may be useful to relieve transitory insomnia symptoms caused by caffeine consumption, unlike the prescription drug ZPD.
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Bredsdorff, Lea, Eva Bay Wedebye, Nikolai Georgiev Nikolov, Torben Hallas-Møller, and Kirsten Pilegaard. "Potential adverse effects of raspberry ketone sold as food supplement." Toxicology Letters 229 (September 2014): S171. http://dx.doi.org/10.1016/j.toxlet.2014.06.586.

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5

Lutsch, Daniel J., Clayton L. Camic, Andrew R. Jagim, Riley R. Stefan, Brandon J. Cox, Rachel N. Tauber, and Shaine E. Henert. "Effects of a Multi-Ingredient Preworkout Supplement Versus Caffeine on Energy Expenditure and Feelings of Fatigue during Low-Intensity Treadmill Exercise in College-Aged Males." Sports 8, no. 10 (September 25, 2020): 132. http://dx.doi.org/10.3390/sports8100132.

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The primary purpose of this study was to examine the acute effects of a multi-ingredient (i.e., caffeine, green tea extract, Yohimbe extract, capsicum annum, coleus extract, L-carnitine, beta-alanine, tyrosine) preworkout supplement versus a dose of caffeine (6 mg·kg−1) on energy expenditure during low-intensity exercise. The effects of these treatments on substrate utilization, gas exchange, and psychological factors were also investigated. Twelve males (mean ± SD: age = 22.8 ± 2.4 years) completed three bouts of 60 min of treadmill exercise on separate days after consuming a preworkout supplement, 6 mg·kg−1 of caffeine, or placebo in a randomized fashion. The preworkout and caffeine supplements resulted in significantly greater energy expenditure (p < 0.001, p = 0.006, respectively), V˙O2 (p < 0.001, p = 0.007, respectively), V˙CO2 (p = 0.006, p = 0.049, respectively), and V˙E (p < 0.001, p = 0.007, respectively) compared to placebo (collapsed across condition). There were no differences among conditions, however, for rates of fat or carbohydrate oxidation or respiratory exchange ratio. In addition, the preworkout supplement increased feelings of alertness (p = 0.015) and focus (p = 0.005) 30-min postingestion and decreased feelings of fatigue (p = 0.014) during exercise compared to placebo. Thus, the preworkout supplement increased energy expenditure and measures of gas exchange to the same extent as 6 mg·kg−1 of caffeine with concomitant increased feelings of alertness and focus and decreased feelings of fatigue.
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Prins, Philip J., Andrew P. Koutnik, Dominic P. D’Agostino, Christopher Q. Rogers, Jacob F. Seibert, Jillian A. Breckenridge, Daniel S. Jackson, Edward J. Ryan, Jeffrey D. Buxton, and Dana L. Ault. "Effects of an Exogenous Ketone Supplement on Five‐Kilometer Running Performance." Journal of Human Kinetics 72, no. 1 (March 31, 2020): 115–27. http://dx.doi.org/10.2478/hukin-2019-0114.

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AbstractNumerous oral ketone supplements are marketed with the claim that they will rapidly induce ketosis and improve exercise performance. The purpose of this study was to assess exercise performance time and related physiological, metabolic and perceptual responses of recreational endurance runners after ingestion of a commercially available oral ketone supplement. Recreational endurance runners (n = 10; age: 20.8 ± 1.0 years; body mass: 68.9 ± 5.6 kg; height: 175.6 ± 4.9 cm) participated in a double-blind, crossover, repeated-measures study where they were randomized to 300 mg.kg-1 body weight of an oral β-hydroxybutyrate-salt + Medium Chain Triglyceride (βHB-salt+MCT) ketone supplement or a flavor matched placebo (PLA) 60 min prior to performing a 5-km running time trial (5KTT) on a treadmill. Time, HR, RPE, affect, RER, VO2, VCO2, and VE were measured during the 5-km run. The Session RPE and affect (Feeling Scale) were obtained post-5KTT. Plasma glucose, lactate and ketones were measured at baseline, 60-min post-supplement, and immediately post-5KTT. Plasma R-βHB (endogenous isomer) was elevated from baseline and throughout the entire protocol under the βHB-salt+MCT condition (p < 0.05). No significant difference (58.3 ± 100.40 s; 95% CI: -130.12 – 13.52; p = 0.100) was observed between the βHB-salt+MCT supplement (1430.0 ± 187.7 s) and the PLA (1488.3 ± 243.8 s) in time to complete the 5KTT. No other differences (p > 0.05) were noted in any of the other physiological, metabolic or perceptual measures.
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Baumeister, Anna, Joachim Gardemann, Manfred Fobker, Verena Spiegler, and Tobias Fischer. "Short-Term Influence of Caffeine and Medium-Chain Triglycerides on Ketogenesis: A Controlled Double-Blind Intervention Study." Journal of Nutrition and Metabolism 2021 (June 15, 2021): 1–9. http://dx.doi.org/10.1155/2021/1861567.

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Background. Ketone bodies are a highly relevant topic in nutrition and medicine. The influence of medium-chain triglycerides (MCT) on ketogenesis is well known and has been successfully used in ketogenic diets for many years. Nevertheless, the effects of MCTs and coconut oil on the production of ketone bodies have only partially been investigated. Furthermore, the increased mobilisation of free fatty acids and release of catabolic hormones by caffeine suggest an influence of caffeine on ketogenesis. Methods. In a controlled, double-blind intervention study, seven young healthy subjects received 10 mL of tricaprylin (C8), tricaprin (C10), C8/C10 (50% C8, 50% C10), or coconut oil with or without 150 mg of caffeine, in 250 mL of decaffeinated coffee, over ten interventions. At baseline and after every 40 minutes, for 4 h, ßHB and glucose in capillary blood as well as caffeine in saliva were measured. Furthermore, questionnaires were used to survey sensory properties, side effects, and awareness of hunger and satiety. Results. The interventions with caffeine caused an increase in ßHB levels—in particular, the interventions with C8 highly impacted ketogenesis. The effect decreased with increased chain lengths. All interventions showed a continuous increase in hunger and diminishing satiety. Mild side effects (total = 12) occurred during the interventions. Conclusions. The present study demonstrated an influence of caffeine and MCT on ketogenesis. The addition of caffeine showed an additive effect on the ketogenic potential of MCT and coconut oil. C8 showed the highest ketogenicity.
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Fischer, Tobias, Ulrike Och, Ira Klawon, Tim Och, Marianne Grüneberg, Manfred Fobker, Ursula Bordewick-Dell, and Thorsten Marquardt. "Effect of a Sodium and Calcium DL-β-Hydroxybutyrate Salt in Healthy Adults." Journal of Nutrition and Metabolism 2018 (2018): 1–8. http://dx.doi.org/10.1155/2018/9812806.

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Background. Ketone body therapy and supplementation are of high interest for several medical and nutritional fields. The intake of ketone bodies is often discussed in relation to rare metabolic diseases, such as multiple acyl-CoA dehydrogenase deficiency (MADD), that have no alternatives for treatment. Case reports showed positive results of therapy using ketone bodies. The number of ketone body salts offered on the wellness market is increasing steadily. More information on the kinetics of intake, safety, and tolerance of these products is needed. Methods. In a one-dose kinetic study, six healthy subjects received an intervention (0.5 g/kg bw) using a commercially available ketone body supplement. The supplement contained a mixture of sodium and calcium D-/L-β-hydroxybutyrate (βHB) as well as food additives. The blood samples drawn in the study were tested for concentrations of D-βHB, glucose, and electrolytes, and blood gas analyses were done. Data on sensory evaluation and observed side effects of the supplement were collected. The product also went through chemical food analysis. Results. The supplement led to a significant increase of D-βHB concentration in blood 2.5 and 3 h after oral intake (p=0.033; p=0.043). The first significant effect was measured after 2 h with a mean value of 0.598 ± 0.300 mmol/L at the peak, which was recorded at 2.5 h. Changes in serum electrolytes and BGA were largely unremarkable. Taking the supplement was not without side effects. One subject dropped out due to gastrointestinal symptoms and two others reported similar but milder problems. Conclusions. Intake of a combination of calcium and sodium D-/L-βHB salt shows a slow resorption with a moderate increase of D-βHB in serum levels. An influence of βHB salts on acid-base balance could not be excluded by this one-dose study. Excessive regular consumption without medical observation is not free of adverse effects. The tested product can therefore not be recommended unconditionally.
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9

Ratamess, Nicholas A., Jay R. Hoffman, Ryan Ross, Miles Shanklin, Avery D. Faigenbaum, and Jie Kang. "Effects of an Amino Acid/Creatine Energy Supplement on the Acute Hormonal Response to Resistance Exercise." International Journal of Sport Nutrition and Exercise Metabolism 17, no. 6 (December 2007): 608–23. http://dx.doi.org/10.1123/ijsnem.17.6.608.

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The authors aimed to examine the acute hormonal and performance responses to resistance exercise with and without prior consumption of an amino acid/creatine/energy supplement. Eight men performed a resistance-exercise protocol at baseline (BL), 20 min after consuming a supplement (S) consisting of essential amino acids, creatine, taurine, caffeine, and glucuronolactone or a maltodextrin placebo (P). Venous blood samples were obtained before and immediately after (IP), 15 min (15P), and 30 min (30P) after each protocol. Area under the curve of resistance-exercise volume revealed that BL was significantly less than S (10%) and P (8.6%). For fatigue rate, only S (18.4% ± 12.0%) was significantly lower than BL (32.9% ± 8.4%). Total testosterone (TT) and growth hormone (GH) were significantly elevated at IP and 15P in all conditions. The GH response was significantly lower, however, in S and P than in BL. The TT and GH responses did not differ between S and P. These results indicated that a supplement consisting of amino acids, creatine, taurine, caffeine, and glucuronolactone can modestly improve high-intensity endurance; however, the anabolic-hormonal response was not augmented.
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McBride, Brian F., Angeliki K. Karapanos, Agnes Krudysz, Jeffrey Kluger, Craig I. Coleman, and C. Michael White. "Electrocardiographic and Hemodynamic Effects of a Multicomponent Dietary Supplement Containing Ephedra and Caffeine." JAMA 291, no. 2 (January 14, 2004): 216. http://dx.doi.org/10.1001/jama.291.2.216.

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Dissertations / Theses on the topic "Effects of a ketone caffeine supplement"

1

Short, Jay. "Effects of A Ketone/Caffeine Supplement On Cycling and Cognitive Performance." The Ohio State University, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=osu1492436132235977.

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2

Bowling, Madison Lee Bowling. "Effects of A Ketone-Caffeine Supplement On Cycling and Cognitive Performance in Chronic Keto-Adapted Participants." The Ohio State University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=osu1523882697428788.

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