Journal articles: 'EFMD'

1

Meier, C., S. Seufert, and D. Euler. "Quality assessment and development in the course of the EFMD CEL programme accreditation." Journal of Computer Assisted Learning 28, no. 1 (September 12, 2011): 52–64. http://dx.doi.org/10.1111/j.1365-2729.2011.00442.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Kalika, Michel, Gordon Shenton, and Pierre-Louis Dubois. "What happens if a business school disappears? The intellectual foundations of BSIS." Journal of Management Development 35, no. 7 (August 8, 2016): 878–88. http://dx.doi.org/10.1108/jmd-10-2014-0120.

Full text

Abstract:

Purpose – The FNEGE and then EFMD have been interested in defining a methodology that would make it possible to highlight the impact of a business school on its home territory. This has led to the development of the “Business School Impact System” (BSIS), which is introduced in this paper. The paper aims to discuss these issues. Design/methodology/approach – The paper is structured as follows. The authors first present the methodological issues of the work that led us to develop the “BSIS” (EFMD, 2014). In a second section, the authors present BSIS in more detail. Findings – Based on the exploratory interviews and the literature review, the authors could first identify three main categories of impact: the financial impact; the impact on the regional community; and the impact on attractiveness and image. Originality/value – The first benefit of BSIS is linked to the creation of an information system on impact. Second, the BSIS process increases the awareness inside the business school regarding the significance of this issue. Third, the authors observe that for numerous members of the business school the question of the impact of their activity gives them a better image of their job, of what they are doing and why they are doing it. Fourth, the BSIS report constitutes a powerful tool for communication with the stakeholders. The final benefit lies in the reviewers’ recommendations on how to improve the impact of the business school.

APA, Harvard, Vancouver, ISO, and other styles

3

Stonham, Paul. "The 1992 EFMD case development workshop: The effectiveness of cases as a teaching tool." European Management Journal 11, no. 1 (March 1993): 132–34. http://dx.doi.org/10.1016/0263-2373(93)90034-f.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Olsen, J. F., and N. Suga. "Combination-sensitive neurons in the medial geniculate body of the mustached bat: encoding of target range information." Journal of Neurophysiology 65, no. 6 (June 1, 1991): 1275–96. http://dx.doi.org/10.1152/jn.1991.65.6.1275.

Full text

Abstract:

1. Delay-tuned combination-sensitive neurons (FM-FM neurons) have been discovered in the dorsal and medial divisions of the medial geniculate body (MGB) of the mustached bat (Pteronotus parnellii). In this paper we present evidence for a thalamic origin for FM-FM neurons. Our examination of the response properties of FM-FM neurons indicates that the neural mechanism of delay-tuning depends on coincidence detection and involves an interaction between neural inhibition and excitation. 2. The biosonar pulse (P) and its echo (E) produced and heard by the mustached bat consist of four harmonics; each harmonic contains a constant frequency (CF) component and a frequency modulated (FM) component. Thus the pulse-echo pair contains eight CF components (PCF1-4, ECF1-4) and eight FM components (PFM1-4, EFM1-4). The stimuli used in this study consisted of CF, FM, and CF-FM sounds: paired CF-FM sounds were used to simulate any two harmonics of pulse-echo pairs. The responses of FM-FM neurons in the MGB were recorded extracellularly. We found that FM-FM neurons respond poorly or not at all to single sounds, respond strongly to paired sounds, and are tuned to the frequency and amplitude of each sound of the pair and to the time interval separating them (simulated echo delay). 3. All FM-FM neurons are facilitated by paired FM sounds and most are facilitated by paired CF sounds. Best facilitative frequencies measured with paired CF sounds fall outside the frequency ranges of the CF components of biosonar signals, whereas best facilitative frequencies measured with paired FM sounds fall within the frequency ranges of the FM components of biosonar signals. Thus FM-FM neurons are expected to respond selectively to combinations of FM components in biosonar signals. The FM components of pulse-echo pairs essential to facilitate FM-FM neurons are the FM component of the fundamental of the pulse (PFM1) in combination with the FM component of the second, third, or fourth harmonic of an echo (EFM2, EFM3, EFM4; collectively, EFMn). 4. The frequency combinations to which FM-FM neurons are tuned reflect small deviations from the harmonic relationship such as occurs in combinations of FM components from pulses and Doppler-shifted echoes. Compared with CF/CF neurons, however, FM-FM neurons are broadly tuned to stimulus frequency. Thus FM-FM neurons are Doppler-shift tolerant and relatively unspecialized for processing velocity information in the frequency domain.(ABSTRACT TRUNCATED AT 400 WORDS)

APA, Harvard, Vancouver, ISO, and other styles

5

Dzialo, Maria C., Kyle J. Travaglini, Sean Shen, Kevin Roy, Guillaume F. Chanfreau, Joseph A. Loo, and Steven G. Clarke. "Translational Roles of Elongation Factor 2 Protein Lysine Methylation." Journal of Biological Chemistry 289, no. 44 (September 17, 2014): 30511–24. http://dx.doi.org/10.1074/jbc.m114.605527.

Full text

Abstract:

Methylation of various components of the translational machinery has been shown to globally affect protein synthesis. Little is currently known about the role of lysine methylation on elongation factors. Here we show that in Saccharomyces cerevisiae, the product of the EFM3/YJR129C gene is responsible for the trimethylation of lysine 509 on elongation factor 2. Deletion of EFM3 or of the previously described EFM2 increases sensitivity to antibiotics that target translation and decreases translational fidelity. Furthermore, the amino acid sequences of Efm3 and Efm2, as well as their respective methylation sites on EF2, are conserved in other eukaryotes. These results suggest the importance of lysine methylation modification of EF2 in fine tuning the translational apparatus.

APA, Harvard, Vancouver, ISO, and other styles

6

Calhoun, Mark A., Sadiyah Sabah Chowdhury, Mark Tyler Nelson, John J. Lannutti, Rebecca B. Dupaix, and Jessica O. Winter. "Effect of Electrospun Fiber Mat Thickness and Support Method on Cell Morphology." Nanomaterials 9, no. 4 (April 20, 2019): 644. http://dx.doi.org/10.3390/nano9040644.

Full text

Abstract:

Electrospun fiber mats (EFMs) are highly versatile biomaterials used in a myriad of biomedical applications. Whereas some facets of EFMs are well studied and can be highly tuned (e.g., pore size, fiber diameter, etc.), other features are under characterized. For example, although substrate mechanics have been explored by several groups, most studies rely on Young’s modulus alone as a characterization variable. The influence of fiber mat thickness and the effect of supports are variables that are often not considered when evaluating cell-mechanical response. To assay the role of these features in EFM scaffold design and to improve understanding of scaffold mechanical properties, we designed EFM scaffolds with varying thickness (50–200 µm) and supporting methodologies. EFM scaffolds were comprised of polycaprolactone and were either electrospun directly onto a support, suspended across an annulus (3 or 10 mm inner diameter), or “tension-released” and then suspended across an annulus. Then, single cell spreading (i.e., Feret diameter) was measured in the presence of these different features. Cells were sensitive to EFM thickness and suspended gap diameter. Overall, cell spreading was greatest for 50 µm thick EFMs suspended over a 3 mm gap, which was the smallest thickness and gap investigated. These results are counterintuitive to conventional understanding in mechanobiology, which suggests that stiffer materials, such as thicker, supported EFMs, should elicit greater cell polarization. Additional experiments with 50 µm thick EFMs on polystyrene and polydimethylsiloxane (PDMS) supports demonstrated that cells can “feel” the support underlying the EFM if it is rigid, similar to previous results in hydrogels. These results also suggest that EFM curvature may play a role in cell response, separate from Young’s modulus, possibly because of internal tension generated. These parameters are not often considered in EFM design and could improve scaffold performance and ultimately patient outcomes.

APA, Harvard, Vancouver, ISO, and other styles

7

Shirinkina, E. V. "CHANGES IN EDUCATIONAL TECHNOLOGIES OF CORPORATE TRAINING IN THE DIGITAL ECONOMY." Bulletin of Udmurt University. Series Economics and Law 30, no. 1 (March 2, 2020): 67–71. http://dx.doi.org/10.35634/2412-9593-2020-30-1-67-71.

Full text

Abstract:

The relevance of the study conducted in this article is due to the fact that the development of educational technologies in the digital economy will allow in the next 15 years to introduce accelerated methods in education, radically improving the learning of the material, and create communication systems “man - man”, “man - machine”, “man - society”. The purpose of this study is to identify and review the main factors affecting the transformation of the role of corporate training in the modern world, and key global trends in corporate training today. The objectives of the study were: search and creative development of information on the factors and trends of corporate training; prioritization and structured description of the identified factors and trends. The empirical base of the study was the materials of the European Foundation for Management Development (EFMD), the Association for the Development of Talent (ATD), and case studies of corporate universities. Practical significance consists in identifying the factors that influence and may affect the change in the corporate learning process and its global trends. This study allows one to form corporate training business models in the conditions of the digital economy development.

APA, Harvard, Vancouver, ISO, and other styles

8

Sarathy, Chaitra, Martina Kutmon, Michael Lenz, Michiel E. Adriaens, Chris T. Evelo, and Ilja C. W. Arts. "EFMviz: A COBRA Toolbox Extension to Visualize Elementary Flux Modes in Genome-Scale Metabolic Models." Metabolites 10, no. 2 (February 12, 2020): 66. http://dx.doi.org/10.3390/metabo10020066.

Full text

Abstract:

Elementary Flux Modes (EFMs) are a tool for constraint-based modeling and metabolic network analysis. However, systematic and automated visualization of EFMs, capable of integrating various data types is still a challenge. In this study, we developed an extension for the widely adopted COBRA Toolbox, EFMviz, for analysis and graphical visualization of EFMs as networks of reactions, metabolites and genes. The analysis workflow offers a platform for EFM visualization to improve EFM interpretability by connecting COBRA toolbox with the network analysis and visualization software Cytoscape. The biological applicability of EFMviz is demonstrated in two use cases on medium (Escherichia coli, iAF1260) and large (human, Recon 2.2) genome-scale metabolic models. EFMviz is open-source and integrated into COBRA Toolbox. The analysis workflows used for the two use cases are detailed in the two tutorials provided with EFMviz along with the data used in this study.

APA, Harvard, Vancouver, ISO, and other styles

9

Shirinkina, E. V. "E-LEARNING TECHNOLOGY PLATFORMS IN THE LMS SYSTEM OF COMPANIES." Bulletin of Udmurt University. Series Economics and Law 31, no. 3 (June 8, 2021): 415–20. http://dx.doi.org/10.35634/2412-9593-2021-31-3-415-420.

Full text

Abstract:

The relevance of this study is due to the fact that in conditions of a limited budget, companies face important questions: what system to choose to support their HR cycle; to stop at a boxed solution or to develop their own; how to correctly calculate the costs of implementation and support of the system. Misunderstandings between technology platform developers and consumers may be hidden in the terminology used. When a decision-maker is looking for a system for storing educational content, the choice may not be the most optimal option, but the option that is most popular or has the widest functionality. The article presents the key trends and directions, technologies and solutions that are in the focus of corporate training; identifies the key technological platforms of e-learning in the human capital management system. The empirical basis of the study was the materials of the international consulting companies EFMD, ELearning Inside, Technavio, Metaari. The practical significance of this study lies in revealing the issues that companies face when choosing or creating their training system. The introduction of e-learning technological platforms in the human capital management system will not be easy in any case, but already at the beginning of this path it is necessary to keep the end user in mind.

APA, Harvard, Vancouver, ISO, and other styles

10

Shirinkina, Elena V. "Designing the pedagogical design of the educational environment of the university." Vestnik of Saint Petersburg State University of Culture, no. 1 (46) (March 2021): 156–62. http://dx.doi.org/10.30725/2619-0303-2021-1-156-162.

Full text

Abstract:

The relevance of the research is due to the fact that the educational environment of the university is an integral element of the educational process, which is constantly changing, even at a fairly high speed. In this regard, pedagogical design in such conditions concerns not only educational programs, but also the environment itself. The author considers a new category «pedagogical design», defines how the pedagogical designer differs from the methodologist or methodologist; Why is a pedagogical design design mechanism needed? The empirical basis of the study was the data of international studies by Deloitte «Digital Education Survey», Goldman, EFMD, Metaari, Technavio, as well as data from domestic studies by HR-academy and the Sberbank Corporate University. The novelty of the research lies in the fact that the author presents a mechanism for designing the pedagogical design of the educational environment of the university, based on obtaining, comprehending, checking one’s own experience and analyzing best practices. The practical significance of the study lies in the fact that the results obtained will allow educational institutions to structure their work in such a way as to calmly relate to changes, responding to requests from the labor market, while making changes made the training solution the most effective.

APA, Harvard, Vancouver, ISO, and other styles

11

Ullah, Ehsan, Mona Yosafshahi, and Soha Hassoun. "Towards scaling elementary flux mode computation." Briefings in Bioinformatics 21, no. 6 (November 20, 2019): 1875–85. http://dx.doi.org/10.1093/bib/bbz094.

Full text

Abstract:

Abstract While elementary flux mode (EFM) analysis is now recognized as a cornerstone computational technique for cellular pathway analysis and engineering, EFM application to genome-scale models remains computationally prohibitive. This article provides a review of aspects of EFM computation that elucidates bottlenecks in scaling EFM computation. First, algorithms for computing EFMs are reviewed. Next, the impact of redundant constraints, sensitivity to constraint ordering and network compression are evaluated. Then, the advantages and limitations of recent parallelization and GPU-based efforts are highlighted. The article then reviews alternative pathway analysis approaches that aim to reduce the EFM solution space. Despite advances in EFM computation, our review concludes that continued scaling of EFM computation is necessary to apply EFM to genome-scale models. Further, our review concludes that pathway analysis methods that target specific pathway properties can provide powerful alternatives to EFM analysis.

APA, Harvard, Vancouver, ISO, and other styles

12

Meyer, Camille. "Social finance and the commons paradigm." Management Decision 58, no. 4 (September 13, 2019): 786–96. http://dx.doi.org/10.1108/md-01-2019-0133.

Full text

Abstract:

Purpose The concept of the commons, or common goods, is becoming increasingly widespread in the world of research and among civil society. The commons are defined as resources that are shared and collectively managed by communities of users, such as natural commons (e.g. fisheries, the climate) and knowledge commons (e.g. Wikipedia, open-source software). The paper aims to discuss this issue. Design/methodology/approach This paper presents the findings of the PhD dissertation “Social finance and the commons,” recipient of the 2017 Emerald/EFMD Outstanding Doctoral Research Award, category Management and Governance, sponsored by Management Decision. Adopting an interdisciplinary perspective of the commons, this dissertation investigates how community enterprises govern financial resources as commons to serve the common good. To do so, it builds on data collected on community development banks in Brazil and complementary currencies in multiple countries. Findings The findings explain how collective action favors the implementation of new forms of governance and management potentially enabling finance to create and support communities. In doing so, this dissertation provides insights on the transformative power of some governance features for the creation of commons. Originality/value This dissertation advances theoretical and conceptual foundations for a theory of the commons in management sciences. It contributes to a new conceptualization of the commons, especially by extending the concept of commons to finance and showing the variety of commons according to governance structures and values. It also generates theoretical insights into social and community entrepreneurship research through an in-depth investigation of social finance organizations.

APA, Harvard, Vancouver, ISO, and other styles

13

Guil, Francisco, José F. Hidalgo, and José M. García. "Boosting the extraction of elementary flux modes in genome-scale metabolic networks using the linear programming approach." Bioinformatics 36, no. 14 (July 10, 2020): 4163–70. http://dx.doi.org/10.1093/bioinformatics/btaa280.

Full text

Abstract:

Abstract Motivation Elementary flux modes (EFMs) are a key tool for analyzing genome-scale metabolic networks, and several methods have been proposed to compute them. Among them, those based on solving linear programming (LP) problems are known to be very efficient if the main interest lies in computing large enough sets of EFMs. Results Here, we propose a new method called EFM-Ta that boosts the efficiency rate by analyzing the information provided by the LP solver. We base our method on a further study of the final tableau of the simplex method. By performing additional elementary steps and avoiding trivial solutions consisting of two cycles, we obtain many more EFMs for each LP problem posed, improving the efficiency rate of previously proposed methods by more than one order of magnitude. Availability and implementation Software is freely available at https://github.com/biogacop/Boost_LP_EFM. Contact fguil@um.es Supplementary information Supplementary data are available at Bioinformatics online.

APA, Harvard, Vancouver, ISO, and other styles

14

Winter, Daniel L., Gene Hart-Smith, and Marc R. Wilkins. "Characterization of Protein Methyltransferases Rkm1, Rkm4, Efm4, Efm7, Set5 and Hmt1 Reveals Extensive Post-Translational Modification." Journal of Molecular Biology 430, no. 1 (January 2018): 102–18. http://dx.doi.org/10.1016/j.jmb.2017.11.009.

Full text

APA, Harvard, Vancouver, ISO, and other styles

15

Guil, Francisco, José F. Hidalgo, and José M. García. "Flux Coupling and the Objective Functions’ Length in EFMs." Metabolites 10, no. 12 (November 28, 2020): 489. http://dx.doi.org/10.3390/metabo10120489.

Full text

Abstract:

Structural analysis of constraint-based metabolic network models attempts to find the network’s properties by searching for subsets of suitable modes or Elementary Flux Modes (EFMs). One useful approach is based on Linear Program (LP) techniques, which introduce an objective function to convert the stoichiometric and thermodynamic constraints into a linear program (LP), using additional constraints to generate different nontrivial modes. This work introduces FLFS-FC (Fixed Length Function Sampling with Flux Coupling), a new approach to increase the efficiency of generation of large sets of different EFMs for the network. FLFS-FC is based on the importance of the length of the objective functions used in the associated LP problem and the imposition of additional negative constraints. Our proposal overrides some of the known drawbacks associated with the EFM extraction, such as the appearance of unfeasible problems or multiple repeated solutions arising from different LP problems.

APA, Harvard, Vancouver, ISO, and other styles

16

Issa, Anindita N., Kelly Baker, Derek Pate, Royal Law, Tesfaye Bayleyegn, and Rebecca S. Noe. "Evaluation of Oklahoma’s Electronic Death Registration System and Event Fatality Markers for Disaster-Related Mortality Surveillance – Oklahoma USA, May 2013." Prehospital and Disaster Medicine 34, no. 02 (April 2019): 125–31. http://dx.doi.org/10.1017/s1049023x19000189.

Full text

Abstract:

Introduction:Official counts of deaths attributed to disasters are often under-reported, thus adversely affecting public health messaging designed to prevent further mortality. During the Oklahoma (USA) May 2013 tornadoes, Oklahoma State Health Department Division of Vital Records (VR; Oklahoma City, Oklahoma USA) piloted a flagging procedure to track tornado-attributed deaths within its Electronic Death Registration System (EDRS). To determine if the EDRS was capturing all tornado-attributed deaths, the Centers for Disease Control and Prevention (CDC; Atlanta, Georgia USA) evaluated three event fatality markers (EFM), which are used to collate information about deaths for immediate response and retrospective research efforts.Methods:Oklahoma identified 48 tornado-attributed deaths through a retrospective review of hospital morbidity and mortality records. The Centers for Disease Control and Prevention (CDC; Atlanta, Georgia USA) analyzed the sensitivity, timeliness, and validity for three EFMs, which included: (1) a tornado-specific flag on the death record; (2) a tornado-related term in the death certificate; and (3) X37, the International Classification of Diseases, 10th Revision (ICD-10) code in the death record for Victim of a Cataclysmic Storm, which includes tornadoes.Results:The flag was the most sensitive EFM (89.6%; 43/48), followed by the tornado term (75.0%; 36/48), and the X37 code (56.2%; 27/48). The most-timely EFM was the flag, which took 2.0 median days to report (range 0-10 days), followed by the tornado term (median 3.5 days; range 1-21), and the X37 code (median >10 days; range 2-122). Over one-half (52.1%; 25/48) of the tornado-attributed deaths were missing at least one EFM. Twenty-six percent (11/43) of flagged records had no tornado term, and 44.1% (19/43) had no X37 code. Eleven percent (4/36) of records with a tornado term did not have a flag.Conclusion:The tornado-specific flag was the most sensitive and timely EFM. Using the flag to collate death records and identify additional deaths without the tornado term and X37 code may improve immediate response and retrospective investigations. Moreover, each of the EFMs can serve as quality controls for the others to maximize capture of all disaster-attributed deaths from vital statistics records in the EDRS.Issa AN, Baker K, Pate D, Law R, Bayleyegn T, Noe RS. Evaluation of Oklahoma’s Electronic Death Registration System and event fatality markers for disaster-related mortality surveillance – Oklahoma USA, May 2013. Prehosp Disaster Med. 2019;34(2):125–131

APA, Harvard, Vancouver, ISO, and other styles

17

Hidalgo, José Francisco, Francisco Guil, and José Manuel García. "A new approach to obtaining EFMs using graph methods based on the shortest path between end nodes." Genomics and Computational Biology 2, no. 1 (September 12, 2016): 30. http://dx.doi.org/10.18547/gcb.2016.vol2.iss1.e30.

Full text

Abstract:

Genome-scale metabolic networks let us understand the behaviour of the metabolism in the cells of living organisms. The availability of great amounts of such data gives the scientific community the opportunity to infer in silico new metabolic knowledge. Elementary Flux Modes (EFM) are minimal contained pathways or subsets of a metabolic network that are very useful to achieving the comprehension of a very specific metabolic function (as well as dysfunctions), and to get the knowledge to develop new drugs. Metabolic networks can have large connectivity and, therefore, EFMs resolution faces a combinational explosion challenge to be solved. In this paper we propose a new approach to obtain EFMs based on graph theory, the balanced graph concept and the shortest path between end nodes. Our proposal uses the shortest path between end nodes (input and output nodes) that finds all the pathways in the metabolic network and is able to prioritise the pathway search accounting the biological mean pursued. Our technique has two phases, the exploration phase and the characterisation one, and we show how it works in a well-known case study. We also demonstrate the relevance of the concept of balanced graph to achieve to the full list of EFMs.

APA, Harvard, Vancouver, ISO, and other styles

18

Lovis, Christian, Anne Moen, John Mantas, Alfred Winter, Mira Hercigonja-Szekeres, Lacramioara Stoicu-Tivadar, and Patrick Weber. "EFMI." Yearbook of Medical Informatics 28, no. 01 (April 25, 2019): 301–6. http://dx.doi.org/10.1055/s-0039-1677900.

Full text

APA, Harvard, Vancouver, ISO, and other styles

19

Lovis, Christian, George Mihalas, John Mantas, Niels Peek, Ran Balicer, Izet Masic, and Lacramioara Stoicu-Tivadar. "EFMI." Yearbook of Medical Informatics 27, no. 01 (April 22, 2018): 296–301. http://dx.doi.org/10.1055/s-0038-1641209.

Full text

APA, Harvard, Vancouver, ISO, and other styles

20

Lovis, Christian, Catherine Chronaki, Parisis Gallo, John Mantas, Louise Pape-Haugaard, Rebecca Randell, Lacramioara Stoicu-Tivadar, Patrick Weber, and Alfred Winter. "EFMI." Yearbook of Medical Informatics 29, no. 01 (April 17, 2020): 300–305. http://dx.doi.org/10.1055/s-0040-1701970.

Full text

APA, Harvard, Vancouver, ISO, and other styles

21

Gallos, Parisis G., John Mantas, Louise Pape-Haugaard, Rebecca Randell, Lacramioara Stoicu-Tivadar, Patrick Weber, and Alfred Winter. "EFMI." Yearbook of Medical Informatics 30, no. 01 (April 21, 2021): 340–45. http://dx.doi.org/10.1055/s-0041-1726498.

Full text

APA, Harvard, Vancouver, ISO, and other styles

22

Park, Su Bin, Jin Yong Kang, Jong Min Kim, Seon Kyeong Park, Seul Ki Yoo, Uk Lee, Dae-Ok Kim, and Ho Jin Heo. "Effect of Aruncus dioicus var. kamtschaticus Extract on Neurodegeneration Improvement: Ameliorating Role in Cognitive Disorder Caused by High-Fat Diet Induced Obesity." Nutrients 11, no. 6 (June 12, 2019): 1319. http://dx.doi.org/10.3390/nu11061319.

Full text

Abstract:

This study was performed to estimate the possibility of using an ethyl acetate fraction from Aruncus dioicus var. kamtschaticus (EFAD) on metabolic syndrome that is induced by a high-fat diet (HFD). It was demonstrated that EFAD suppresses lipid accumulation and improves insulin resistance (IR) caused by Tumor necrosis factor alpha (TNF-α) in in-vitro experiments using the 3T3-L1 cell. In in-vivo tests, C57BL/6 mice were fed EFAD at 20 and 40 mg/kg body weight (BW) for four weeks after the mice were fed HFD for 15 weeks to induce obesity. EFAD significantly suppressed the elevation of BW and improved impaired glucose tolerance in obese mice. Additionally, this study showed that EFAD has an ameliorating effect on obesity-induced cognitive disorder with behavioral tests. The effect of EFAD on peripheral-IR improvement was confirmed by serum analysis and western blotting in peripheral tissues. Additionally, EFAD showed an ameliorating effect on HFD-induced oxidative stress, impaired cholinergic system and mitochondrial dysfunction, which are interrelated symptoms of neurodegeneration, such as Alzheimer’s disease and central nervous system (CNS)-IR in brain tissue. Furthermore, we confirmed that EFAD improves CNS-IR by confirming the IR-related factors in brain tissue. Consequently, this study suggests the possibility of using EFAD for the prevention of neurodegeneration by improving metabolic syndrome that is caused by HFD.

APA, Harvard, Vancouver, ISO, and other styles

23

Simha, K. R. Y. "e-EFM." Resonance 12, no. 6 (June 2007): 86–88. http://dx.doi.org/10.1007/s12045-007-0065-7.

Full text

APA, Harvard, Vancouver, ISO, and other styles

24

Abuín-Porras, Vanesa, Paula Maldonado-Tello, Mónica de la Cueva-Reguera, David Rodríguez-Sanz, César Calvo-Lobo, Daniel López-López, Emmanuel Navarro-Flores, and Carlos Romero-Morales. "Comparison of Lateral Abdominal Musculature Activation during Expiration with an Expiratory Flow Control Device Versus the Abdominal Drawing-in Maneuver in Healthy Women: A Cross-Sectional Observational Pilot Study." Medicina 56, no. 2 (February 19, 2020): 84. http://dx.doi.org/10.3390/medicina56020084.

Full text

Abstract:

Background and Objectives: The purpose of the present study was to quantify and compare lateral abdominal musculature thickness, including the transverse abdominis (TrA), internal oblique (IO), and external oblique (EO) muscles, via rehabilitative ultrasound imaging (RUSI) during the use of the expiratory flow control device (EFCD) versus the classic abdominal drawing-in maneuver (ADIM). Materials and Methods: A cross-sectional observational pilot study. Twenty-one women were recruited and assessed the thickness of each muscle (TrA, IO, and EO) by ultrasound imaging at rest, during the ADIM, and during expiration with the EFCD. Waist circumference was also measured under the same circumstances. Results: Statistically significant differences were observed between ADIM, EFCD, and at rest condition for the thickness of the TrA (p = 0.001) and IO (p = 0.039). Moreover, statistically significant differences for TrAb at rest compared with the ADIM (p = 0.001, Cohen’s d = 2.183) and at rest and with the EFCD (p = 0.001, Cohen’s d = 2.843). In addition, between ADIM and EFCD were not statistically significant, although a moderate effect size was found (p = 0.055, Cohen’s d = 0.694). For the IO muscle thickness, significant differences were reported between the EFCD and at rest (p = 0.038), Cohen’s d = 0.081). Conclusions: Significant differences in the increase of the thickness of the TrA and IO muscles during the use of the EFCD and the ADIM with respect to rest. In addition, for the TrA, statistically significant differences were found during expiration with the EFCD with respect to the ADIM. Expiration with EFCD can be a useful method for the activation of the TrA.

APA, Harvard, Vancouver, ISO, and other styles

25

Mahout, Maxime, Ross P. Carlson, and Sabine Peres. "Answer Set Programming for Computing Constraints-Based Elementary Flux Modes: Application to Escherichia coli Core Metabolism." Processes 8, no. 12 (December 14, 2020): 1649. http://dx.doi.org/10.3390/pr8121649.

Full text

Abstract:

Elementary Flux Modes (EFMs) provide a rigorous basis to systematically characterize the steady state, cellular phenotypes, as well as metabolic network robustness and fragility. However, the number of EFMs typically grows exponentially with the size of the metabolic network, leading to excessive computational demands, and unfortunately, a large fraction of these EFMs are not biologically feasible due to system constraints. This combinatorial explosion often prevents the complete analysis of genome-scale metabolic models. Traditionally, EFMs are computed by the double description method, an efficient algorithm based on matrix calculation; however, only a few constraints can be integrated into this computation. They must be monotonic with regard to the set inclusion of the supports; otherwise, they must be treated in post-processing and thus do not save computational time. We present aspefm, a hybrid computational tool based on Answer Set Programming (ASP) and Linear Programming (LP) that permits the computation of EFMs while implementing many different types of constraints. We apply our methodology to the Escherichia coli core model, which contains 226×106 EFMs. In considering transcriptional and environmental regulation, thermodynamic constraints, and resource usage considerations, the solution space is reduced to 1118 EFMs that can be computed directly with aspefm. The solution set, for E. coli growth on O2 gradients spanning fully aerobic to anaerobic, can be further reduced to four optimal EFMs using post-processing and Pareto front analysis.

APA, Harvard, Vancouver, ISO, and other styles

26

Suhendra, Edward, Chih-Hua Chang, Wen-Che Hou, and Yi-Chin Hsieh. "A Review on the Environmental Fate Models for Predicting the Distribution of Engineered Nanomaterials in Surface Waters." International Journal of Molecular Sciences 21, no. 12 (June 26, 2020): 4554. http://dx.doi.org/10.3390/ijms21124554.

Full text

Abstract:

Exposure assessment is a key component in the risk assessment of engineered nanomaterials (ENMs). While direct and quantitative measurements of ENMs in complex environmental matrices remain challenging, environmental fate models (EFMs) can be used alternatively for estimating ENMs’ distributions in the environment. This review describes and assesses the development and capability of EFMs, focusing on surface waters. Our review finds that current engineered nanomaterial (ENM) exposure models can be largely classified into three types: material flow analysis models (MFAMs), multimedia compartmental models (MCMs), and spatial river/watershed models (SRWMs). MFAMs, which is already used to derive predicted environmental concentrations (PECs), can be used to estimate the releases of ENMs as inputs to EFMs. Both MCMs and SRWMs belong to EFMs. MCMs are spatially and/or temporally averaged models, which describe ENM fate processes as intermedia transfer of well-mixed environmental compartments. SRWMs are spatiotemporally resolved models, which consider the variability in watershed and/or stream hydrology, morphology, and sediment transport of river networks. As the foundation of EFMs, we also review the existing and emerging ENM fate processes and their inclusion in recent EFMs. We find that while ENM fate processes, such as heteroaggregation and dissolution, are commonly included in current EFMs, few models consider photoreaction and sulfidation, evaluation of the relative importance of fate processes, and the fate of weathered/transformed ENMs. We conclude the review by identifying the opportunities and challenges in using EFMs for ENMs.

APA, Harvard, Vancouver, ISO, and other styles

27

Rolf, Engelbrecht, and Hasman Arie. "Information on EFMI Working Groups." Yearbook of Medical Informatics 15, no. 01 (August 2006): 225–37. http://dx.doi.org/10.1055/s-0038-1638499.

Full text

APA, Harvard, Vancouver, ISO, and other styles

28

Engelbrecht, Rolf, and Arie Hasman. "Information on EFMI Working Groups." Yearbook of Medical Informatics 16, no. 01 (August 2007): 238–45. http://dx.doi.org/10.1055/s-0038-1638555.

Full text

APA, Harvard, Vancouver, ISO, and other styles

29

Engelbrecht, Rolf, and Arie Hasman. "Information on EFMI Working Groups." Yearbook of Medical Informatics 17, no. 01 (August 2008): 235–43. http://dx.doi.org/10.1055/s-0038-1638613.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

Engelbrecht, Rolf, and John Mantas. "Information on EFMI Working Groups." Yearbook of Medical Informatics 18, no. 01 (August 2009): 220–28. http://dx.doi.org/10.1055/s-0038-1638664.

Full text

APA, Harvard, Vancouver, ISO, and other styles

31

Engelbrecht, Rolf, and John Mantas. "Information on EFMI Working Groups." Yearbook of Medical Informatics 19, no. 01 (August 2010): 187–95. http://dx.doi.org/10.1055/s-0038-1638710.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

Kulkarni, K. G. "EFDM: Extended Functional Data Model." Computer Journal 29, no. 1 (January 1, 1986): 38–46. http://dx.doi.org/10.1093/comjnl/29.1.38.

Full text

APA, Harvard, Vancouver, ISO, and other styles

33

Langer, Thierry. "EFMC-ASMC Kongress in Wien." Nachrichten aus der Chemie 66, no. 5 (May 2018): 563. http://dx.doi.org/10.1002/nadc.20184075477.

Full text

APA, Harvard, Vancouver, ISO, and other styles

34

Werner, Anniek, Rick Havinga, Folkert Kuipers, and Henkjan J. Verkade. "Treatment of EFA deficiency with dietary triglycerides or phospholipids in a murine model of extrahepatic cholestasis." American Journal of Physiology-Gastrointestinal and Liver Physiology 286, no. 5 (May 2004): G822—G832. http://dx.doi.org/10.1152/ajpgi.00425.2003.

Full text

Abstract:

Essential fatty acid (EFA) deficiency during cholestasis is mainly due to malabsorption of dietary EFA ( 23 ). Theoretically, dietary phospholipids (PL) may have a higher bioavailability than dietary triglycerides (TG) during cholestasis. We developed murine models for EFA deficiency (EFAD) with and without extrahepatic cholestasis and compared the efficacy of oral supplementation of EFA as PL or as TG. EFAD was induced in mice by feeding a high-fat EFAD diet. After 3 wk on this diet, bile duct ligation was performed in a subgroup of mice to establish extrahepatic cholestasis. Cholestatic and noncholestatic EFAD mice continued on the EFAD diet (controls) or were supplemented for 3 wk with EFA-rich TG or EFA-rich PL. Fatty acid composition was determined in plasma, erythrocytes, liver, and brain. After 4 wk of EFAD diet, induction of EFAD was confirmed by a sixfold increased triene-to-tetraene ratio (T/T ratio) in erythrocytes of noncholestatic and cholestatic mice ( P < 0.001). EFA-rich TG and EFA-rich PL were equally effective in preventing further increase of the erythrocyte T/T ratio, which was observed in cholestatic and noncholestatic nonsupplemented mice (12- and 16-fold the initial value, respectively). In cholestatic mice, EFA-rich PL was superior to EFA-rich TG in decreasing T/T ratios of liver TG and PL (each P < 0.05) and in increasing brain PL concentrations of the long-chain polyunsaturated fatty acids (LCPUFA) docosahexaenoic acid and arachidonic acid (each P < 0.05). We conclude that oral EFA supplementation in the form of PL is more effective than in the form of TG in increasing LCPUFA concentrations in liver and brain of cholestatic EFAD mice.

APA, Harvard, Vancouver, ISO, and other styles

35

Kobayashi, Yosuke, Ryuji Shioya, and Genki Yagawa. "Parallel Eigen Frequency Analysis Using Enriched Free Mesh Method." Key Engineering Materials 462-463 (January 2011): 628–33. http://dx.doi.org/10.4028/www.scientific.net/kem.462-463.628.

Full text

Abstract:

The Enriched Free Mesh Method (EFMM) is a Mixed Method using the Hellinger-Reissner principle. A highly accurate stiffness matrix is computed for each local cluster. As a result, the EFMM can compute the high performance structural problem of low-order mode without an increase in the number of DOF. In this research, a large eigen frequency analysis of discrete model of the EFMM is performed using the Lanczos method on a PC cluster environment.

APA, Harvard, Vancouver, ISO, and other styles

36

Kalinec, F., J. H. Calderón, and B. Monis. "Ultrastructural variations of the urothelial membrane in essential fatty acid (EFA)-deficient rats. A digital densitometric study." Journal of Histochemistry & Cytochemistry 34, no. 12 (December 1986): 1639–44. http://dx.doi.org/10.1177/34.12.3782776.

Full text

Abstract:

The present report deals with a densitometric study of the ultrastructural images of the urothelial membrane of rats in the following experimental conditions: (1) EFA-deficient (EFAD) rats; (2) EFA-sufficient (EFAS) rats; and (3) EFAD rats that were fed the EFAD diet for 30 weeks and received an EFAS diet for the following 10 weeks (EFAD/S group). On electron micrographs of the transitional epithelium of ureters and urinary bladder of these rats, optical density (OD) profiles of the urothelial unit membrane were recorded and digitized using a computer-controlled microdensitometer with a solid-state self-scanned photodiode array sensor. A Gaussian curve was adopted as a model for the distribution of electron-dense material in each osmiophilic leaflet. Gaussian parameters were used to estimate the thickness of the urothelial membrane and of each osmiophilic leaflet, and the amount of electron-dense material and the maximal electron density present in each leaflet. In EFAS rats, the thick urothelial membrane was asymmetric like that of the normal, resulting from a greater thickness of the outer leaflet and a greater electron density of the cytoplasmic one. In EFAD rats, a loss of the characteristic ultrastructural asymmetry and a decrease of the total thickness of the unit membrane were detected. These changes were partially reversed in the EFAD/S rats.

APA, Harvard, Vancouver, ISO, and other styles

37

Hjelte, L., T. Melin, A. Nilsson, and B. Strandvik. "Absorption and metabolism of [3H]arachidonic and [14C]linoleic acid in essential fatty acid-deficient rats." American Journal of Physiology-Gastrointestinal and Liver Physiology 259, no. 1 (July 1, 1990): G116—G124. http://dx.doi.org/10.1152/ajpgi.1990.259.1.g116.

Full text

Abstract:

[3H]arachidonic acid (20:4) and [14C]linoleic acid (18:2) were fed in a triolein emulsion to essential fatty acid-deficient (EFAD) rats and to age-matched controls. Tissues were analyzed for radioactivity of different lipid classes after 1, 2, and 4 h. As in earlier studies [Nilsson and Melin. Am. J. Physiol. 255 (Gastrointest. Liver Physiol. 19): G612-G618, 1988], control rats retained more [3H]20:4 than [14C]18:2 in all organs except adipose tissue. In EFAD rats, recovery of [14C]18:2 was increased in small intestine, liver, heart, and kidneys. In comparison to controls, EFAD rats retained much more [14C]18:2 in phospholipids of these organs. The increase in the incorporation of both 3H and 14C into phosphatidylethanolamine was particularly pronounced. Another striking feature was the drastic increase in the retention after 4 h of 14C in cardiolipin, which is specifically located in the inner mitochondrial membrane. In contrast, incorporation of both 3H and 14C into phosphatidylinositol was decreased or unchanged in EFAD rats. Although fecal fat excretion was increased there was no evidence for a malabsorption or an increased retention in intestinal triacyglycerol of the radioactive fatty acids in EFAD rats. The proportion of [14C]18:2 that had been converted to [14C]20:4 was generally low but increased significantly with time in the liver and intestine of EFAD rats.

APA, Harvard, Vancouver, ISO, and other styles

38

Ayre, K. J., and A. J. Hulbert. "Effects of changes in dietary fatty acids on isolated skeletal muscle functions in rats." Journal of Applied Physiology 80, no. 2 (February 1, 1996): 464–71. http://dx.doi.org/10.1152/jappl.1996.80.2.464.

Full text

Abstract:

The effects of manipulating dietary levels of essential polyunsaturated fatty acids on the function of isolated skeletal muscles in male Wistar rats were examined. Three isoenergetic diets were used: an essential fatty acid-deficient diet (EFAD), a diet high in essential (n-6) fatty acids [High (n-6)], and a diet enriched with essential (n-3) fatty acids [High (n-3)]. After 9 wk, groups of rats on each test diet were fed a stock diet of laboratory chow for a further 6 wk. Muscle function was examined by using a battery of five tests for soleus (slow twitch) and extensor digitorum longus (EDL; fast twitch). Tests included single muscle twitches, sustained tetanic contractions, posttetanic potentiation, sustained high-frequency stimulation, and intermittent low-frequency stimulation. Results for muscles from the High (n-6) and High (n-3) groups were very similar. However, the EFAD diet resulted in significantly lower muscular tensions and reduced response times compared with the High (n-6) and High (n-3) diets. Peak twitch tension in soleus muscles was 16-21% less in the EFAD group than in the High (n-6) and High (n-3) groups, respectively [analysis of variance (ANOVA), P < 0.01). During high-frequency stimulation, EDL muscles from the EFAD rats fatigued 32% more quickly (ANOVA, P < 0.01)]. Also, twitch contraction and half-relaxation times were significantly 5-7% reduced in the EFAD group (ANOVA, P < 0.01). During intermittent low-frequency stimulation, soleus muscles from the EFAD group generated 25-28% less tension than did the other groups (ANOVA, P < 0.01), but in EDL muscles from the EFAD group, endurance was 20% greater than in the High (n-6) group (ANOVA, P < 0.05). After 6 wk on the stock diet, there were no longer any differences between the dietary groups. Manipulation of dietary fatty acids results in significant, but reversible, effects in muscles of rats fed an EFAD diet.

APA, Harvard, Vancouver, ISO, and other styles

39

Peres, Sabine, Stefan Schuster, and Philippe Dague. "Thermodynamic constraints for identifying elementary flux modes." Biochemical Society Transactions 46, no. 3 (May 9, 2018): 641–47. http://dx.doi.org/10.1042/bst20170260.

Full text

Abstract:

Metabolic pathway analysis is a key method to study metabolism and the elementary flux modes (EFMs) is one major concept allowing one to analyze the network in terms of minimal pathways. Their practical use has been hampered by the combinatorial explosion of their number in large systems. The EFMs give the possible pathways at steady state, but the real pathways are limited by biological constraints. In this review, we display three different methods that integrate thermodynamic constraints in terms of Gibbs free energy in the EFMs computation.

APA, Harvard, Vancouver, ISO, and other styles

40

Pierce, Gary L., Darren P. Casey, Jess G. Fiedorowicz, Douglas R. Seals, Timothy B. Curry, Jill N. Barnes, DeMaris R. Wilson, and Harald M. Stauss. "Aortic pulse wave velocity and reflecting distance estimation from peripheral waveforms in humans: detection of age- and exercise training-related differences." American Journal of Physiology-Heart and Circulatory Physiology 305, no. 1 (July 1, 2013): H135—H142. http://dx.doi.org/10.1152/ajpheart.00916.2012.

Full text

Abstract:

We hypothesized that demographic/anthropometric parameters can be used to estimate effective reflecting distance (EfRD), required to derive aortic pulse wave velocity (APWV), a prognostic marker of cardiovascular risk, from peripheral waveforms and that such estimates can discriminate differences in APWV and EfRD with aging and habitual endurance exercise in healthy adults. Ascending aortic pressure waveforms were derived from peripheral waveforms (brachial artery pressure, n = 25; and finger volume pulse, n = 15) via a transfer function and then used to determine the time delay between forward- and backward-traveling waves (Δ tf-b). True EfRDs were computed as directly measured carotid-femoral pulse wave velocity (CFPWV) × ½Δ tf-b and then used in regression analysis to establish an equation for EfRD based on demographic/anthropometric data (EfRD = 0.173·age + 0.661·BMI + 34.548 cm, where BMI is body mass index). We found good agreement between true and estimated APWV (Pearson's R2 = 0.43; intraclass correlation = 0.64; both P < 0.05) and EfRD ( R2 = 0.24; intraclass correlation = 0.40; both P < 0.05). In young sedentary (22 ± 2 years, n = 6), older sedentary (62 ± 1 years, n = 24), and older endurance-trained (61 ± 2 years, n = 14) subjects, EfRD (from demographic/anthropometric parameters), APWV, and ½Δ tf-b (from brachial artery pressure waveforms) were 52.0 ± 0.5, 61.8 ± 0.4, and 60.6 ± 0.5 cm; 6.4 ± 0.3, 9.6 ± 0.2, and 8.1 ± 0.2 m/s; and 82 ± 3, 65 ± 1 and 76 ± 2 ms (all P < 0.05), respectively. Our results demonstrate that APWV derived from peripheral waveforms using age and BMI to estimate EfRD correlates with CFPWV in healthy adults. This method can reliably detect the distal shift of the reflecting site with age and the increase in APWV with sedentary aging that is attenuated with habitual endurance exercise.

APA, Harvard, Vancouver, ISO, and other styles

41

Zhang, Yang, Kenan Liu, Wuyun Zhao, Wei Zhang, and Fei Dai. "Stability Analysis for Milling Process with Variable Pitch and Variable Helix Tools by High-Order Full-Discretization Methods." Mathematical Problems in Engineering 2020 (July 26, 2020): 1–14. http://dx.doi.org/10.1155/2020/4517969.

Full text

Abstract:

Chatter is one of the significant limitations in the milling process, which may cause poor surface quality, reduced productivity, and accelerated tool wear. Variable pitch and variable helix tools can be used to suppress regenerative chatter. This study extends the high-order full-discretization methods (FDMs) to predict the stability of milling with variable pitch and variable helix tools. The time-periodic delay-differential equation (DDE) with multiple delays is used to model the milling process using variable pitch and variable helix tools. Then, the DDE with multiple delays is reexpressed by the state-space equation. Meanwhile, the spindle rotational period is divided into many small-time intervals, and the state space equation is integrated on the small-time interval. Then, the high-order interpolation polynomials are used to approximate the state term, and the weights related to the time delay are employed to approximate the time-delay term. The second-order, third-order, and fourth-order extended FDMs (2nd EFDM, 3rd EFDM, and 4th EFDM) are compared with the benchmark in terms of the rate of convergence. It is found that the 2nd EFDM, 3rd EFDM, and 4th EFDM converge faster than the benchmark method. The difference between the curves obtained by different EFDMs and the reference curve is very small. There is no need to extend hypersecond FDMs to analyze the stability of milling with variable pitch and variable helix tools.

APA, Harvard, Vancouver, ISO, and other styles

42

Ho, Bach Q. "Effects of Learning Process and Self-Efficacy in Real-World Education for Sustainable Development." Sustainability 13, no. 1 (January 4, 2021): 403. http://dx.doi.org/10.3390/su13010403.

Full text

Abstract:

To solve the “wicked problems” of sustainability, education for sustainable development (EfSD) that raises the young generation to become change agents is necessary. For this purpose, fieldtrips that educate students in the real world about other stakeholders are effective, but since sustainable issues do not have clear solutions, cooperative learning (CL) in which students learn from each other is useful. The purpose of this study is to clarify the influence of the learning process on learning outcomes and their influence on learning objectives in real-world EfSD using CL. A hypothesis model consisting of seven hypotheses was set up, and a questionnaire survey of high school students who participated in the real-world EfSD was conducted. Results of the structural equation modeling of data from 2441 respondents supported all seven hypotheses. Implicit learning as a learning process promotes knowledge acquisition as a learning outcome, while explicit learning enhances self-efficacy. Although knowledge acquisition promotes citizenship development as the learning objective of EfSD, self-efficacy does not promote citizenship development. Self-efficacy affects knowledge acquisition more than implicit learning. This study contributes to EfSD research by clarifying the difference in the effects of the learning process.

APA, Harvard, Vancouver, ISO, and other styles

43

Sæther, Thomas, Thien N. Tran, Helge Rootwelt, Hans J. Grav, Bjørn O. Christophersen, and Trine B. Haugen. "Essential fatty acid deficiency induces fatty acid desaturase expression in rat epididymis, but not in testis." Reproduction 133, no. 2 (February 2007): 467–77. http://dx.doi.org/10.1530/rep-06-00294.

Full text

Abstract:

On the molecular level, essential fatty acid deficiency (EFAD) has been associated with induced fatty acid (FA) desaturase expression and activity in several tissues. However, there seem to be exceptions. In the present study, we examine the effects of EFAD in the male rat genital tract, combining FA analysis, gene expression studies, and morphological evaluation of epididymal spermatozoa. When feeding 21-day-old Wistar rats, a fat-free diet for 6 weeks, an increase in 18:1n-9 and 20:3n-9 and a concomitant decrease in the 18:2n-6 and 20:4n-6 species are seen in testis, as well as in liver. However, with regard to desaturase expression the rat testis seems to be unresponsive to EFAD conditions, in contrast to other organs studied. In the sexually mature testis none of the desaturases (SCD1, SCD2, D5D, or D6D) are induced in response to lowered contents of polyunsaturated FAs. This also applies tocaputepididymis, while EFAD sensitivity is regained incaudaepididymis, where the desaturases are upregulated. The FA profile of epididymal spermatozoa is increasingly affected by EFAD during the transport from testis tocaudaepididymis. Furthermore, a significant increase in the number of abnormal spermatozoa is observed incaudaepididymis.

APA, Harvard, Vancouver, ISO, and other styles

44

Xu, Qingwen, Haofei Kuang, Laurent Kneip, and Sören Schwertfeger. "Rethinking the Fourier-Mellin Transform: Multiple Depths in the Camera’s View." Remote Sensing 13, no. 5 (March 5, 2021): 1000. http://dx.doi.org/10.3390/rs13051000.

Full text

Abstract:

Remote sensing and robotics often rely on visual odometry (VO) for localization. Many standard approaches for VO use feature detection. However, these methods will meet challenges if the environments are feature-deprived or highly repetitive. Fourier-Mellin Transform (FMT) is an alternative VO approach that has been shown to show superior performance in these scenarios and is often used in remote sensing. One limitation of FMT is that it requires an environment that is equidistant to the camera, i.e., single-depth. To extend the applications of FMT to multi-depth environments, this paper presents the extended Fourier-Mellin Transform (eFMT), which maintains the advantages of FMT with respect to feature-deprived scenarios. To show the robustness and accuracy of eFMT, we implement an eFMT-based visual odometry framework and test it in toy examples and a large-scale drone dataset. All these experiments are performed on data collected in challenging scenarios, such as, trees, wooden boards and featureless roofs. The results show that eFMT performs better than FMT in the multi-depth settings. Moreover, eFMT also outperforms state-of-the-art VO algorithms, such as ORB-SLAM3, SVO and DSO, in our experiments.

APA, Harvard, Vancouver, ISO, and other styles

45

Wu, Yong Jian, Ping Zhou, Pin Shang, and Tian You Chai. "Intelligent Operation Control for the Fused Magnesia Production." Advanced Materials Research 391-392 (December 2011): 1450–54. http://dx.doi.org/10.4028/www.scientific.net/amr.391-392.1450.

Full text

Abstract:

An electro-fused magnesia furnace (EFMF) is used to produce electro-fused magnesia. Due to the complex dynamic characteristics of the EFMF production process, it is difficult to achieve the satisfactory control performances only by the independent conventional control method. As a result, the lower loop control with manual operations is still widely used in practice. However, the manual operation cannot ensure that the actual production qualities and the energy consumption of unit production meet the technical requirements all the time. In this paper, an intelligent operation control strategy is developed for the EFMF to automatically adjust the setpoints of the lower level control system. Based on the proposed intelligent control strategy, an intelligent control system for the EFMF is built and implemented on site. Industrial application has demonstrated that the intelligent control system can achieve reliable, accurate and timely control performances.

APA, Harvard, Vancouver, ISO, and other styles

46

NAGAOKA, Shinsuke, Yasushi NAKABAYASHI, and Genki YAGAWA. "Fluid-Structure Coupled Analysis Using EFMM." TRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series A 76, no. 764 (2010): 449–57. http://dx.doi.org/10.1299/kikaia.76.449.

Full text

APA, Harvard, Vancouver, ISO, and other styles

47

Nicholas, Daniel J. "IFMA and EFMA Announce Name Changes." International Bulletin of Missionary Research 32, no. 1 (January 2008): 43. http://dx.doi.org/10.1177/239693930803200113.

Full text

APA, Harvard, Vancouver, ISO, and other styles

48

Diamond, J. R., I. Pesek, S. Ruggieri, and M. J. Karnovsky. "Essential fatty acid deficiency during acute puromycin nephrosis ameliorates late renal injury." American Journal of Physiology-Renal Physiology 257, no. 5 (November 1, 1989): F798—F807. http://dx.doi.org/10.1152/ajprenal.1989.257.5.f798.

Full text

Abstract:

Puromycin aminonucleoside (PA) nephrosis is associated with a significant increase in the glomerular macrophage number during peak proteinuria. The significance of this observation remains uncertain. An essential fatty acid-deficient (EFAD) diet depletes normal rat glomeruli of resident macrophages and alters glomerular eicosanoid metabolism. In this study, we found that an EFAD diet, administered only for the duration of the acute nephrotic phase, significantly ameliorated the recurrent albuminuria, renal dysfunction, and morphological injury characteristic of the late, recurrent phase of chronic aminonucleoside nephrosis. Glomerular macrophage number, isolated glomerular thromboxane B2 production, and circulating leukocyte and monocyte counts were significantly reduced in nephrotic rats on the EFAD diet 2 wk after PA injection, which temporally corresponds to peak albuminuria. The exact mechanism(s) by which the EFAD diet conferred protection in the late phase of chronic aminonucleoside nephrosis and lowered glomerular macrophage number during the acute nephrotic phase remain to be elucidated.

APA, Harvard, Vancouver, ISO, and other styles

49

Kopp, U. C., D. M. Farley, L. A. Smith, and H. R. Knapp. "Essential fatty acid deficiency impairs the responsiveness of renal pelvic sensory receptors." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 268, no. 1 (January 1, 1995): R164—R170. http://dx.doi.org/10.1152/ajpregu.1995.268.1.r164.

Full text

Abstract:

The role of prostaglandins in renal sensory receptor activation was examined in rats fed an essential fatty acid-deficient (EFAD) diet to cause tissue arachidonate depletion. Littermates fed a standard diet were used as controls. In anesthetized rats, the increases in afferent renal nerve activity due to increasing ureteral pressure 2.5, 5, 7.5, 10, 12.5, and 15 mmHg were significantly reduced by the EFAD diet (P < 0.02): 3 +/- 5, 3 +/- 5, 11 +/- 5, 9 +/- 5, 19 +/- 3, and 17 +/- 5%, respectively, in EFAD rats and 23 +/- 11, 36 +/- 15, 50 +/- 15, 52 +/- 8, 72 +/- 17, and 90 +/- 19%, respectively, in control rats. In EFAD rats, addition of prostaglandin E2 (PGE2) to the renal pelvic perfusate restored the afferent renal nerve activity response to increased ureteral pressure toward that in control rats. PGE2 had no effect in control rats. Also the afferent renal nerve activity responses to renal pelvic perfusion with bradykinin at 4, 20, 100, and 500 micrograms/ml were significantly suppressed by the EFAD diet (P < 0.01): 13 +/- 15, 5 +/- 7, 60 +/- 19, and 63 +/- 20%, respectively, in EFAD rats and 122 +/- 23, 142 +/- 31, 172 +/- 19, and 190 +/- 39%, respectively, in control rats. These results demonstrate an important role for arachidonate metabolites, particularly PGE2, in renal sensory receptor activation. Together with our previous studies showing that indomethacin blocks the afferent renal nerve activity responses to increased ureteral pressure or bradykinin, the present studies provide strong evidence for an essential role of prostaglandins in renal sensory receptor activation.

APA, Harvard, Vancouver, ISO, and other styles

50

Wang, Yahui, Wei Wang, Yongqiang Lv, Wangliang Zheng, Zhiqiang Mi, Guangqian Pei, Xiaoping An, et al. "Characterization and complete genome sequence analysis of novel bacteriophage IME-EFm1 infecting Enterococcus faecium." Journal of General Virology 95, no. 11 (November 1, 2014): 2565–75. http://dx.doi.org/10.1099/vir.0.067553-0.

Full text

Abstract:

We isolated and characterized a novel virulent bacteriophage, IME-EFm1, specifically infecting multidrug-resistant Enterococcus faecium. IME-EFm1 is morphologically similar to members of the family Siphoviridae. It was found capable of lysing a wide range of our E. faecium collections, including two strains resistant to vancomycin. One-step growth tests revealed the host lysis activity of phage IME-EFm1, with a latent time of 30 min and a large burst size of 116 p.f.u. per cell. These biological characteristics suggested that IME-EFm1 has the potential to be used as a therapeutic agent. The complete genome of IME-EFm1 was 42 597 bp, and was linear, with terminally non-redundant dsDNA and a G+C content of 35.2 mol%. The termini of the phage genome were determined with next-generation sequencing and were further confirmed by nuclease digestion analysis. To our knowledge, this is the first report of a complete genome sequence of a bacteriophage infecting E. faecium. IME-EFm1 exhibited a low similarity to other phages in terms of genome organization and structural protein amino acid sequences. The coding region corresponded to 90.7 % of the genome; 70 putative ORFs were deduced and, of these, 29 could be functionally identified based on their homology to previously characterized proteins. A predicted metallo-β-lactamase gene was detected in the genome sequence. The identification of an antibiotic resistance gene emphasizes the necessity for complete genome sequencing of a phage to ensure it is free of any undesirable genes before use as a therapeutic agent against bacterial pathogens.

APA, Harvard, Vancouver, ISO, and other styles

Journal articles on the topic 'EFMD'

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles