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Academic literature on the topic 'EFMR'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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Journal articles on the topic "EFMR"

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Purgold, I., J. Seidel, G. Skirl, U. Brandl, A. Abicht, E. Holinski-Feder, and I. Graneß. "Frühkindliche Epilepsie: Epilepsy Female restricted with Mental Retardation (EFMR)." Kinder- und Jugendmedizin 12, no. 06 (2012): 371–75. http://dx.doi.org/10.1055/s-0038-1629310.

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ZusammenfassungBerichtet wird über ein inzwischen 3 Jahre altes Mädchen, das erstmals im Alter von 5 Monaten epileptische Anfälle zeigte. Diese liefen zunächst als Halbseitenanfälle rechts und ohne Fieber ab. Im Verlauf traten dann etwa alle 4–6 Wochen nahezu eigengesetzlich clusterhaft generalisierte tonisch-klonische Anfälle auf, die zum Teil auch durch Fieber getriggert wurden. Durch Einsatz verschiedener Antikonvulsiva (Carbamazepin, Oxcarbazepin, Valproat, Levetirazetam, Brom, Phenobarbital) konnte bisher nur eine Anfallsreduktion erreicht werden. Differenzialdiagnostisch wurden u. a. ein Watanabe-und Dravet-Syndrom ausgeschlossen. Erst die Untersuchung des PCDH19-Gens ergab den Nachweis einer krankheitsverursachenden Mutation, sodass damit die Diagnose EFMR gestellt werden konnte.

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Cooper, Edward C. "The Cadherin Superfamily and Epileptogenesis: End of the Beginning?" Epilepsy Currents 9, no. 3 (April 24, 2009): 87–89. http://dx.doi.org/10.1111/j.1535-7511.2009.01302.x.

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X-Linked Protocadherin 19 Mutations Cause Female-Limited Epilepsy and Cognitive Impairment. Dibbens LM, Tarpey PS, Hynes K, Bayly MA, Scheffer IE, Smith R, Bomar J, Sutton E, Vandeleur L, Shoubridge C, Edkins S, Turner SJ, Stevens C, O'Meara S, Tofts C, Barthorpe S, Buck G, Cole J, Halliday K, Jones D, Lee R, Madison M, Mironenko T, Varian J, West S, Widaa S, Wray P, Teague J, Dicks E, Butler A, Menzies A, Jenkinson A, Shepherd R, Gusella JF, Afawi Z, Mazarib A, Neufeld MY, Kivity S, Lev D, Lerman-Sagie T, Korczyn AD, Derry CP, Sutherland GR, Friend K, Shaw M, Corbett M, Kim HG, Geschwind DH, Thomas P, Haan E, Ryan S, McKee S, Berkovic SF, Futreal PA, Stratton MR, Mulley JC, Gecz J. Nat Genetics 2008;40(6):776–781. Epilepsy and mental retardation limited to females (EFMR) is a disorder with an X-linked mode of inheritance and an unusual expression pattern. Disorders arising from mutations on the X chromosome are typically characterized by affected males and unaffected carrier females. In contrast, EFMR spares transmitting males and affects only carrier females. Aided by systematic resequencing of 737 X chromosome genes, we identified different protocadherin 19 ( PCDH19) gene mutations in seven families with EFMR. Five mutations resulted in the introduction of a premature termination codon. Study of two of these demonstrated nonsense-mediated decay of PCDH19 mRNA. The two missense mutations were predicted to affect adhesiveness of PCDH19 through impaired calcium binding. PCDH19 is expressed in developing brains of human and mouse and is the first member of the cadherin superfamily to be directly implicated in epilepsy or mental retardation.

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Terracciano, A., N. Specchio, F. Darra, A. Sferra, B. Dalla Bernardina, F. Vigevano, and E. Bertini. "Somatic mosaicism of PCDH19 mutation in a family with low-penetrance EFMR." neurogenetics 13, no. 4 (September 6, 2012): 341–45. http://dx.doi.org/10.1007/s10048-012-0342-9.

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Antelmi, Elena, Massimo Mastrangelo, Francesca Bisulli, Luigina Spaccini, Carlotta Stipa, Barbara Mostacci, Davide Mei, Renzo Guerrini, and Paolo Tinuper. "Semiological study of ictal affective behaviour in epilepsy and mental retardation limited to females (EFMR)." Epileptic Disorders 14, no. 3 (September 2012): 304–9. http://dx.doi.org/10.1684/epd.2012.0526.

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Ding, Daniel D. "The Passive Voice and Social Values in Science." Journal of Technical Writing and Communication 32, no. 2 (April 2002): 137–54. http://dx.doi.org/10.2190/efmr-bjf3-ce41-84kk.

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This article claims that two social values in science—falsifiability of science and cooperation among scientists—determine use of passives in scientific communication. Scientists do not always develop valid theories, so scientific experiments must be amenable to being repeated and found invalid. This requires that the experiments must not be discrete events. Science is also a cooperative enterprise. As an integral part of science, scientific writing employs more passives than actives to focus on materials, methods, figures, processes, tables, concepts, etc. Use of passives to focus on the physical world helps de-emphasize discreteness of scientific experiments. Besides, it also helps remove personal qualifications of observing experimental results. Finally, it enhances cooperation among working scientists by providing a common knowledge base of scientific work—things and objects. Looked at in this way, the passive voice in scientific writing represents professional practices of science instead of personal stylistic choices of individual scientists.

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Olsen, J. F., and N. Suga. "Combination-sensitive neurons in the medial geniculate body of the mustached bat: encoding of target range information." Journal of Neurophysiology 65, no. 6 (June 1, 1991): 1275–96. http://dx.doi.org/10.1152/jn.1991.65.6.1275.

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1. Delay-tuned combination-sensitive neurons (FM-FM neurons) have been discovered in the dorsal and medial divisions of the medial geniculate body (MGB) of the mustached bat (Pteronotus parnellii). In this paper we present evidence for a thalamic origin for FM-FM neurons. Our examination of the response properties of FM-FM neurons indicates that the neural mechanism of delay-tuning depends on coincidence detection and involves an interaction between neural inhibition and excitation. 2. The biosonar pulse (P) and its echo (E) produced and heard by the mustached bat consist of four harmonics; each harmonic contains a constant frequency (CF) component and a frequency modulated (FM) component. Thus the pulse-echo pair contains eight CF components (PCF1-4, ECF1-4) and eight FM components (PFM1-4, EFM1-4). The stimuli used in this study consisted of CF, FM, and CF-FM sounds: paired CF-FM sounds were used to simulate any two harmonics of pulse-echo pairs. The responses of FM-FM neurons in the MGB were recorded extracellularly. We found that FM-FM neurons respond poorly or not at all to single sounds, respond strongly to paired sounds, and are tuned to the frequency and amplitude of each sound of the pair and to the time interval separating them (simulated echo delay). 3. All FM-FM neurons are facilitated by paired FM sounds and most are facilitated by paired CF sounds. Best facilitative frequencies measured with paired CF sounds fall outside the frequency ranges of the CF components of biosonar signals, whereas best facilitative frequencies measured with paired FM sounds fall within the frequency ranges of the FM components of biosonar signals. Thus FM-FM neurons are expected to respond selectively to combinations of FM components in biosonar signals. The FM components of pulse-echo pairs essential to facilitate FM-FM neurons are the FM component of the fundamental of the pulse (PFM1) in combination with the FM component of the second, third, or fourth harmonic of an echo (EFM2, EFM3, EFM4; collectively, EFMn). 4. The frequency combinations to which FM-FM neurons are tuned reflect small deviations from the harmonic relationship such as occurs in combinations of FM components from pulses and Doppler-shifted echoes. Compared with CF/CF neurons, however, FM-FM neurons are broadly tuned to stimulus frequency. Thus FM-FM neurons are Doppler-shift tolerant and relatively unspecialized for processing velocity information in the frequency domain.(ABSTRACT TRUNCATED AT 400 WORDS)

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Dzialo, Maria C., Kyle J. Travaglini, Sean Shen, Kevin Roy, Guillaume F. Chanfreau, Joseph A. Loo, and Steven G. Clarke. "Translational Roles of Elongation Factor 2 Protein Lysine Methylation." Journal of Biological Chemistry 289, no. 44 (September 17, 2014): 30511–24. http://dx.doi.org/10.1074/jbc.m114.605527.

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Methylation of various components of the translational machinery has been shown to globally affect protein synthesis. Little is currently known about the role of lysine methylation on elongation factors. Here we show that in Saccharomyces cerevisiae, the product of the EFM3/YJR129C gene is responsible for the trimethylation of lysine 509 on elongation factor 2. Deletion of EFM3 or of the previously described EFM2 increases sensitivity to antibiotics that target translation and decreases translational fidelity. Furthermore, the amino acid sequences of Efm3 and Efm2, as well as their respective methylation sites on EF2, are conserved in other eukaryotes. These results suggest the importance of lysine methylation modification of EF2 in fine tuning the translational apparatus.

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Calhoun, Mark A., Sadiyah Sabah Chowdhury, Mark Tyler Nelson, John J. Lannutti, Rebecca B. Dupaix, and Jessica O. Winter. "Effect of Electrospun Fiber Mat Thickness and Support Method on Cell Morphology." Nanomaterials 9, no. 4 (April 20, 2019): 644. http://dx.doi.org/10.3390/nano9040644.

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Electrospun fiber mats (EFMs) are highly versatile biomaterials used in a myriad of biomedical applications. Whereas some facets of EFMs are well studied and can be highly tuned (e.g., pore size, fiber diameter, etc.), other features are under characterized. For example, although substrate mechanics have been explored by several groups, most studies rely on Young’s modulus alone as a characterization variable. The influence of fiber mat thickness and the effect of supports are variables that are often not considered when evaluating cell-mechanical response. To assay the role of these features in EFM scaffold design and to improve understanding of scaffold mechanical properties, we designed EFM scaffolds with varying thickness (50–200 µm) and supporting methodologies. EFM scaffolds were comprised of polycaprolactone and were either electrospun directly onto a support, suspended across an annulus (3 or 10 mm inner diameter), or “tension-released” and then suspended across an annulus. Then, single cell spreading (i.e., Feret diameter) was measured in the presence of these different features. Cells were sensitive to EFM thickness and suspended gap diameter. Overall, cell spreading was greatest for 50 µm thick EFMs suspended over a 3 mm gap, which was the smallest thickness and gap investigated. These results are counterintuitive to conventional understanding in mechanobiology, which suggests that stiffer materials, such as thicker, supported EFMs, should elicit greater cell polarization. Additional experiments with 50 µm thick EFMs on polystyrene and polydimethylsiloxane (PDMS) supports demonstrated that cells can “feel” the support underlying the EFM if it is rigid, similar to previous results in hydrogels. These results also suggest that EFM curvature may play a role in cell response, separate from Young’s modulus, possibly because of internal tension generated. These parameters are not often considered in EFM design and could improve scaffold performance and ultimately patient outcomes.

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Sarathy, Chaitra, Martina Kutmon, Michael Lenz, Michiel E. Adriaens, Chris T. Evelo, and Ilja C. W. Arts. "EFMviz: A COBRA Toolbox Extension to Visualize Elementary Flux Modes in Genome-Scale Metabolic Models." Metabolites 10, no. 2 (February 12, 2020): 66. http://dx.doi.org/10.3390/metabo10020066.

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Elementary Flux Modes (EFMs) are a tool for constraint-based modeling and metabolic network analysis. However, systematic and automated visualization of EFMs, capable of integrating various data types is still a challenge. In this study, we developed an extension for the widely adopted COBRA Toolbox, EFMviz, for analysis and graphical visualization of EFMs as networks of reactions, metabolites and genes. The analysis workflow offers a platform for EFM visualization to improve EFM interpretability by connecting COBRA toolbox with the network analysis and visualization software Cytoscape. The biological applicability of EFMviz is demonstrated in two use cases on medium (Escherichia coli, iAF1260) and large (human, Recon 2.2) genome-scale metabolic models. EFMviz is open-source and integrated into COBRA Toolbox. The analysis workflows used for the two use cases are detailed in the two tutorials provided with EFMviz along with the data used in this study.

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Ullah, Ehsan, Mona Yosafshahi, and Soha Hassoun. "Towards scaling elementary flux mode computation." Briefings in Bioinformatics 21, no. 6 (November 20, 2019): 1875–85. http://dx.doi.org/10.1093/bib/bbz094.

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Abstract While elementary flux mode (EFM) analysis is now recognized as a cornerstone computational technique for cellular pathway analysis and engineering, EFM application to genome-scale models remains computationally prohibitive. This article provides a review of aspects of EFM computation that elucidates bottlenecks in scaling EFM computation. First, algorithms for computing EFMs are reviewed. Next, the impact of redundant constraints, sensitivity to constraint ordering and network compression are evaluated. Then, the advantages and limitations of recent parallelization and GPU-based efforts are highlighted. The article then reviews alternative pathway analysis approaches that aim to reduce the EFM solution space. Despite advances in EFM computation, our review concludes that continued scaling of EFM computation is necessary to apply EFM to genome-scale models. Further, our review concludes that pathway analysis methods that target specific pathway properties can provide powerful alternatives to EFM analysis.

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Dissertations / Theses on the topic "EFMR"

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Cooper, Sharon Rose. "δ-Protocadherin Function: From Molecular Adhesion Properties to Brain Circuitry." The Ohio State University, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=osu1492457066344753.

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Roux, Milena. "Identification and characterization of EFR-interacting proteins." Thesis, University of East Anglia, 2010. https://ueaeprints.uea.ac.uk/26674/.

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Nef, Annliese. "L'élément islamique dans la Sicile normande : identités culturelles et construction d'une nouvelle royauté (XIe - XIIe siècles)." Paris 10, 2001. http://books.openedition.org/efr/5336.

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En 1061, lorsque les Normands entreprennent la conquête de la Sicile, la population insulaire est majoritairement arabo-musulmane, même si la partie orientale demeure profondément hellénisée. Malgré ces difficultés, l'île s'offre comme un terrain de choix pour l'affirmation de la dynastie des Hauteville et la construction d'un pouvoir sans partage. Minoritaires tant d'un point de vue démographique que culturel, ces hommes du nord ont à faire face à un véritable défi. En quelques générations, le comte Roger et ses descendants réussissent à instaurer une royauté qui, pour durer, doit faire l'objet d'un consensus en Sicile même et jouir d'une reconnaissance à l'extérieur. Cette quête de légitimité, qui passe par la mobilisation des héritages latin, islamique et grec (byzantin) qui sont aussi bien ceux des conquérants que des conquis, fait de la Sicile un véritable laboratoire où sont mises à l'épreuve de nouvelles conceptions liées à la royauté. Ce problème politique se pose essentiellement en termes culturels. Comment dire, par exemple, le pouvoir politique dans un contexte trilingue ? Les Normands adoptent ici une position paradoxale. Utilisant le grec, le latin et l'arabe dans l'administration, ils se servent de ces idiomes autant pour reprendre à leur compte les deux traditions insulaires que pour tenir à distance leurs sujets. La référence religieuse n'est pas moins délicate à manier à une époque où la dimension religieuse est étroitement liée à la légitimation du pouvoir royal à Byzance, en Occident et dans les pays islamiques. De la fondation d'évêchés latins à la fin du XIe siècle, on passe à la promotion d'un milieu melkite (chrétien hellénophone et arabophone de Syrie) et mozarabe, puis à l'exaltation d'un monothéisme souple. L'échec de cette tentative unique qui associe trois traditions culturelles découle de l'écart qui se crée peu à peu entre des souverains dont l'identité culturelle mêle des éléments de plus en plus divers et des groupes culturels qui, entre effacement et résistance, ne se retrouvent guère dans cette convergence partielle et limitée au milieu de cour
In 1061, when the Normans begin their conquest of Sicily, the insular population is for the main part of Islamic culture, even if the Oriental regions remain hellenized in depth. In spite of these difficulties, the island offers a perfect ground for the affirmation of the Hautevilles' dynasty and for the construction of an unshared power. Nonetheless, a representing a cultural minority Sicily, these men from the North face a real challenge. Within a few generations, Count Roger and his descent will set up a kingship which, in order to last, must be supported by a consensus in the island and be acknowledged legitimacy outside of it. Such a quest for legitimacy requires the mobilization of Latin, Islamic and Greek (Byzantine) legacies which belong to the conquerors and to the insular population. It transforms Sicily in a true laboratory where new conceptions linked to Kingship are tested. This political problem presents itself essentially in cultural terms. How can, for example, political power be expressed in a trilingual context ? The Norman adopt on this issue a paradoxical position. They use Greek, Latin and Arabic in their administration as much in order to resume with the insular traditions as in order to put distance between themselves and their subjects. Handling the religious reference is no less difficult at a time when the religious dimension is linked straightly to the legitimation of royal power, at Constantinople, as well as in Occident and in the Islamic countries. From the foundation of Latin bishoprics, they go on with the promotion of a Melkite (Christian Hellenophone and Arabophone from Syria) and Mozarabic milieu, ending up with the exaltation of a flexible monotheism. The failure of this unique attempt which associates three cultural traditions is due to the gap that appears little by little between kings whose cultural identity put together more and more diverse elements and cultural groups which, oscillating between disappearance and resistance, do not perceive much of themselves in this partial convergence, limited to the royal Court

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Fenet, Annick. "Caractères et cultes marins des divinités olympiennes dans le monde grec d'Homère à la fin de l'époque hellénistique : contribution à l'étude de la religion des marins grecs." Paris 10, 1998. http://books.openedition.org/efr/5550.

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L'approche religieuse de la mer par les grecs est communément assimilée aux seules figures de Poséidon et des divinités dites + marines, telles les néréides, ino ou les Dioscures. Or, dans la pratique, il s'avère que la majorité des cultes réalisés dans un contexte maritime ou lors d'un voyage en mer s'adressent aux divinités olympiennes ou douze dieux. L'ensemble du travail tend à définir les pratiques religieuses des marins grecs et à considérer la place primordiale qu'y occupent les dieux olympiens. Dans une premiere partie, sont ainsi passées en revue les relations de chacun de ces dieux avec la mer : à travers les récits mythologiques et épiques, puis géographiquement à travers tout le monde grec, région par région, sanctuaire par sanctuaire. Dans une seconde partie, sont décrites les pratiques religieuses spécifiques au monde maritime. En mer, la présence des dieux se manifeste à bord du bateau de differentes manières : par l'ornementation navale, par les noms théophores du navire, par les ancres portant inscriptions ou décors. A terre, en relation avec un voyage maritime, sont consacrés dans des sanctuaires des bateaux sous differentes formes, ainsi que des ancres et des ex-voto de pêche. L'étendue de la période étudiée permet de discerner des évolutions dans les caractères prêtés aux dieux et dans les cultes maritimes, et l'importance de ceux-ci à l'époque archaïque. Leur répartition et la topographie des sanctuaires présentent des cohérences liées aux méthodes et conditions de navigation antique. Le culte marin des divinités olympiennes manifeste de la grande souplesse de la religion grecque - adaptation de personnalités divines a un contexte géographique ou social - tout en formant un ensemble ordonne
The religious approach of the sea by Greeks is commonly classed as the figure of Poseidon and deities so said + marine; like nereids, ino or Dioscuri. But, in the reality it turns out that the majority of worships make in maritime context or in travel by sea address to the Olympian deities or twelve gods. All this study aims to define the religious practices of Greek sailors and to consider the primordial place of the Olympian deities. In the first part, are reviewed relationships of all these gods with the sea : by the mythological and epic words, then geographically through all Greek world, region by region, sanctuary by sanctuary. In the second part, are described the religious practices specific to maritime world. By sea, the presence of gods emerge aboard ships by different ways : by nautical ornamentation, by theophoric names, by anchors with inscriptions or decorations by land, in connection with nautical travel, are dedicated in sanctuaries boats in different forms, anchors and fishing gifts. The duration of period examined permit to discern evolutions in the features of gods and in the maritime worships, and importance of these in the archaic time. There repartition and the topography of sanctuaries present coherences connected to methods and conditions of ancient seamanship. The worship of Olympian deities demonstrate a large adaptability of Greek religion - adaptation of sacred personalities in a geographical or social context - making an arranged whole

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Dalmases, Massegú Alba 1982. "Acquired resistance to the anti-EFGR monoclonal antibody cetuximab in colorectal cancer." Doctoral thesis, Universitat Pompeu Fabra, 2012. http://hdl.handle.net/10803/84183.

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EGFR is a transmembrane tyrosine kinase receptor from the HER family which, upon ligand stimulation, activates different signaling pathways involved in tumorogenesis. EGFR can be targeted by monoclonal antibodies, as cetuximab and panitumumab, which bind to EGFR preventing ligand stimulation of the receptor. Cetuximab and panitumumab are approved for colorectal cancer treatment. However, its clinical success is uniformily limited by the development of acquired drug resistance. We describe a new mechanism of acquired resistance to cetuximab in colorectal cancer that was due to a missense mutation in the EGFR ectodomain (S492R mutation). Upon chronic exposure to cetuximab, colorectal cancer cell lines acquired S492R mutation and became resistant to the treatment. We observed that cetuximab was not able to bind mutant EGFR. Notably, this amino acid change did not affect the ability of panitumumab to bind to EGFR, and panitumumab effectively suppressed growth of mutant cells. EGFRS492R mutation was detected in 2 out of 10 tumor specimens from patients following progression on cetuximab. One of these patients was subsequently treated with single agent panitumumab yielding a partial response. The S492R mutation defines a novel biomarker of resistance to cetuximab but not to panitumumab in colorectal cancer
EGFR és un receptor transmembrana tirosina cinasa de la família HER el qual, després de l’estimulació mitjançant lligands, activa vies de senyalització involucrades en processos tumorogènics. L’EGFR es pot inhibir amb anticossos monoclonals, com cetuximab i panitumumab, que s’uneixen al receptor prevenint-ne l’activació per part dels lligands. Cetuximab i panitumumab estan aprovats per al tractament del càncer colorectal, però el seu ús es veu limitat per el desenvolupament de resistència adquirida al tractament. Nosaltres describim un mecanisme de resistència adquirida a cetuximab en càncer colorectal degut a l’adquisió d’una mutació en el domini extracel•lular de l’EGFR, la mutació S492R. Durant l’exposició crònica a cetuximab, linies cel•lulars de càncer colorectal van adquirir la mutació S492R tornat-se resistents al tractament. Cetuximab no era capaç d’unir-se a l’EGFR mutat. Aquests canvi d’aminoàcid no afectava a l’habilitat que té panitumumab a unir-se al EGFR, pertant, panitumumab suprimia el creixement de les cèl•lules tumorals mutades. Vam detectar la mutació EGFRS492R en 2 de 10 mostres tumorals de pacients que havien recaigut al tractament amb cetuximab. Un d’aquest pacients va ser posteriorment tractat amb panitumumab obtenint-ne una resposta tumoral parcial. La mutació S492R defineix un nou mecanisme de resistència a cetuximab però no a panitumumab en el tractament del càncer colorectal.

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Dickinson, John C. "AFM, CAFM, and EFM Studies of the GaN System." VCU Scholars Compass, 2003. http://scholarscompass.vcu.edu/etd/4522.

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This thesis discusses a variety of techniques based on the atomic force microscope (AFM), and their application to the GaN materials system. In particular, the local conductivity and contact potential of surfaces have been measured using the techniques of Conductive AFM (CAFM) and Surface Potential Electric Force Microscopy (SPEFM), respectively. CAFM studies of GaN surfaces have revealed that prismatic planes around islands and pits on surfaces can lead to enhanced conductivity, which may be related to leakage problems in device applications. With regard to SP-EFM work, the change in surface potential associated with inversion domains on Ga-polar GaN has been imaged, yielding voltage differences up to 90 mV. Given that such inversion domains increase carrier scattering and can degrade device performance, their identification using this technique is important. SP-EFM has also been used to map the local surface potential in the active region of Modulation Doped Field Effect Transistors (MODFET's). This is the first step in a proposed study to investigate the effects of current lag in such devices.

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Fantini, Irene Heleonora Seda Pinto. "Otimização dos codificadores VSELP e EFR por refinamento na modelagem autoregressiva." [s.n.], 2000. http://repositorio.unicamp.br/jspui/handle/REPOSIP/260154.

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Orientador : Luis Geraldo Pedroso Meloni
Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia Eletrica e de Computação
Made available in DSpace on 2018-07-27T18:00:38Z (GMT). No. of bitstreams: 1 Fantini_IreneHeleonoraSedaPinto_M.pdf: 422802 bytes, checksum: 2af12bc93454d9bc1a63115a843727ee (MD5) Previous issue date: 2000
Mestrado

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Saborit, Rojas Enrique. "Update of a Externally Fired Micro Turbine (EFMT) for residential micro combined Heat and Power." Thesis, KTH, Kraft- och värmeteknologi, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-118754.

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Chen, Amber Marie. "Developing and Studying the Effectiveness of EFR Annotations for Chinese Language Learners." BYU ScholarsArchive, 2009. https://scholarsarchive.byu.edu/etd/2299.

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This project is intended to take the film To Live, directed by Zhang Yimou, and apply the Electronic Film Review (EFR) approach to it in a Chinese as a Foreign Language (CFL) setting. The Electronic Film Review project, developed by Alan K. Melby, is aimed at providing a superior language learning experience for Americans learning Chinese. Using feature films as a teaching tool has been found to stimulate and motivate students to achieve higher language levels, but in order for optimal learning to occur the material must be challenging yet accessible to the student. Most feature films, by themselves, are too advanced for the average language learner. The EFR approach provides annotations designed specifically for the feature film with the language learner in mind. These annotations can include access to vocabulary helps, grammar and cultural notes in order to bridge the gap between the learner and the film. It does not alter the film itself. This approach has been used with ESL students (English annotations), French language learners, and with Korean ESL learners (Korean annotations), but has not been developed for students learning Chinese. The purpose of this project is not only to apply the technology of the Electronic Film Review program to a Chinese film for the purpose of aiding Chinese language learners, but also to critique whether or not the tool is effective in helping students to gain better listening comprehensions skills and therefore ultimately better language skills. Previous studies have not shown clear results on this issue. This thesis will briefly review what the EFR project is and how it has been used with other films and languages as well as the findings up to this point. Then it will look at the effects of annotations on several aspects of listening comprehension as well as student preferences and reactions. It will then evaluate the results collectively to determine whether students watching the film without the help of EFR annotations show differing levels of listening comprehension achievement when compared with those using the EFR tools. Suggestions will be made for further improvements.

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Sun, Yu. "Lating Future Land Use Change in the East Fork Little Miami River (EFLMR) Watershed in Ohio." Cincinnati, Ohio : University of Cincinnati, 2009. http://www.ohiolink.edu/etd/view.cgi?acc_num=ucin1236277626.

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Thesis (M.A.)--University of Cincinnati, 2009.
Advisors: Susanna Tong PhD (Committee Chair), Nicholas Dunning PhD (Committee Member), Kevin Raleigh PhD (Committee Member). Title from electronic thesis title page (viewed May 1, 2009). Includes abstract. Keywords: LUCC; Urban expansion; CA_Markov; MCE; EFLMR. Includes bibliographical references.

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Books on the topic "EFMR"

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Liṿyetane ha-efer. [Israel]: Ḳeshev le-shirah, 2010.

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Kaminer, D. ʻOf ha-efer. T.A. [z.o. Tel Aviv]: Y. Golan, 1990.

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Robinson, Relli. Dolah or me-efer. Tel-Aviv: Geṿanim, 2011.

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Tiḳṿah tsomaḥat mi-efer. Netanyah: Aharon Raṭ, 2003.

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Dolah or me-efer. Tel-Aviv: Geṿanim, 2011.

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Harshalom, Avraham. Ḥayim min ha-efer. Tel-Aviv: Hotsaʼat Milo, 1990.

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Mămmădov, Ismai̐yl. Ekran, efir vă dilimiz. Baky: Elm, 1989.

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Arbeli-Raveh, Shoshana. Tipat ha-efer: Shirim. Tel-Aviv: Y. Golan, 1996.

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Harshalom, Avraham. Ḥayim min ha-efer. Tel-Aviv: Hotsaʾat Milo, 1990.

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Raṭh, Aharon. Tiḳṿah tsomaḥat mi-efer. Netanyah: Aharon Rath, 2003.

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Book chapters on the topic "EFMR"

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Li, Zhaoxi, and Xiaohui Guo. "Management of EFM." In Electronic Fetal Monitoring, 19–38. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-15-7364-4_2.

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Mertins, Vanessa, and Carolin Waldner. "Evidenzbasiertes Fundraising-Management (EFM)." In Handbuch Fundraising, 523–42. Wiesbaden: Springer Fachmedien Wiesbaden, 2020. http://dx.doi.org/10.1007/978-3-658-18211-3_39.

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Mertins, Vanessa, and Carolin Waldner. "Evidenzbasiertes Fundraising-Management (EFM)." In Handbuch Fundraising, 1–20. Wiesbaden: Springer Fachmedien Wiesbaden, 2020. http://dx.doi.org/10.1007/978-3-658-08461-5_39-1.

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Sha, Wenqiong, and Xiaohui Guo. "Prenatal and Intrapartum EFM." In Electronic Fetal Monitoring, 65–118. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-15-7364-4_4.

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Hale, Heather. "The European Film Market (EFM)." In How to Work the Film & TV Markets, 50–57. New York: Routledge, 2017.: Routledge, 2017. http://dx.doi.org/10.4324/9781315755359-8.

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Hosseini, Kaveh, and Michael Peter Kennedy. "HK-EFM and HK-SQ-DDSM." In Minimizing Spurious Tones in Digital Delta-Sigma Modulators, 117–29. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4614-0094-3_5.

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Guo, Xiaohui. "Impact of Intrapartum Events on EFM." In Electronic Fetal Monitoring, 235–78. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-15-7364-4_8.

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Kobayashi, Yosuke, and Genki Yagawa. "Parallel Computing for Enriched Free Mesh Method (EFMM)." In Computational Methods in Engineering & Science, 262. Berlin, Heidelberg: Springer Berlin Heidelberg, 2006. http://dx.doi.org/10.1007/978-3-540-48260-4_108.

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Song, Minzhu, and Sujing Zhang. "EFM: A Model for Educational Game Design." In Technologies for E-Learning and Digital Entertainment, 509–17. Berlin, Heidelberg: Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-69736-7_54.

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Zhou, Dake, and Xin Yang. "Feature Fusion Based Face Recognition Using EFM." In Lecture Notes in Computer Science, 643–50. Berlin, Heidelberg: Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-540-30126-4_78.

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Conference papers on the topic "EFMR"

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Du, Fenglei, Greg Bridges, D. J. Thomson, Rama R. Goruganthu, Shawn McBride, and Mike Santana. "Enhancements of Non-contact Measurements of Electrical Waveforms on the Proximity of a Signal Surface Using Groups of Pulses." In ISTFA 2002. ASM International, 2002. http://dx.doi.org/10.31399/asm.cp.istfa2002p0483.

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Abstract With the ever-increasing density and performance of integrated circuits, non-invasive, accurate, and high spatial and temporal resolution electric signal measurement instruments hold the key to performing successful diagnostics and failure analysis. Sampled electrostatic force microscopy (EFM) has the potential for such applications. It provides a noninvasive approach to measuring high frequency internal integrated circuit signals. Previous EFMs operate using a repetitive single-pulse sampling approach and are inherently subject to the signal-to-noise ratio (SNR) problems when test pattern duty cycle times become large. In this paper we present an innovative technique that uses groups of pulses to improve the SNR of sampled EFM systems. The approach can easily provide more than an order-ofmagnitude improvement to the SNR. The details of the approach are presented.

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Schäfer, C., H. Albrecht, M. Hemmel, S. Reitinger, K. Evert, and M. Evert. "Erfolgreiche endoskopische Appendektomie mittels EFTR." In 46. Jahrestagung der Gesellschaft für Gastroenterologie in Bayern e.V. Georg Thieme Verlag KG, 2018. http://dx.doi.org/10.1055/s-0038-1648562.

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Kaikko, Juha, Jari L. H. Backman, Lasse Koskelainen, and Jaakko Larjola. "Optimum Operation of Externally-Fired Microturbine in Combined Heat and Power Generation." In ASME Turbo Expo 2007: Power for Land, Sea, and Air. ASMEDC, 2007. http://dx.doi.org/10.1115/gt2007-28264.

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Externally-fired microturbines (EFMT) yield promising performance in small-scale utilization of biofuels. As in larger gas turbines, the part-load performance of the EFMT is very sensitive to the selected power control method, and in general subject to severe degradation at part load. The control parameters typically include the maximum combustion gas temperature or turbine inlet temperature and the speed of the shaft. At the design point, power generation efficiency can be increased by allowing a fraction of air to bypass the burner and the combustion gas – air heat exchanger. At the same time the heat exchanger size is increased. Therefore, the by-pass flow affects the optimal sizing of the EFMT as well. In this paper, the effect of by-pass flow on the part-load performance of a single-shaft EFMT in combined heat and power generation is analyzed. In the application, the microturbine is operated by the heat demand. The control methods incorporate the use of the maximum combustion gas temperature, the speed of the shaft, and the amount of by-pass air. The focus of the study is to determine the economically optimal control scheme for the engine. The economy model uses the profit flow from the EFMT as a criterion. The results show that the inclusion of the by-pass variation in the control methods can improve the economy of temperature-controlled EFMT at part load but has no benefits when using speed control.

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Sung-Kyo Jung, Stephane Ragot, Claude Lamblin, and Stephane Proust. "An embedded variable bit-rate coder based on GSM EFR: EFR-EV." In ICASSP 2008 - 2008 IEEE International Conference on Acoustics, Speech and Signal Processing. IEEE, 2008. http://dx.doi.org/10.1109/icassp.2008.4518722.

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Zhang, Wenwu, and Magdi Azer. "Intelligent Energy Field Manufacturing (EFM)." In ASME 2006 International Manufacturing Science and Engineering Conference. ASMEDC, 2006. http://dx.doi.org/10.1115/msec2006-21005.

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The nature of manufacturing is using information to control energy field in order to convert material into useful configurations, products, and systems. One way to view manufacturing differently is to explore it from the perspective of energy fields. In this paper, the origination and the evolution of Energy Field Manufacturing (EFM) and the concept of a dynamic M-PIE (Material-Process-Information-Energy) model of manufacturing are reviewed. The generality of energy fields and the importance of re-thinking of traditional and non-traditional manufacturing are discussed. Giving a general definition to intelligence, this paper further broadens the methodology of EFM to Intelligent EFM, which incorporates the ability to gather, interpret and use the information in energy fields, materials and systems in a systematic way. This paper further discusses the meaning and tasks of Intelligent EFM research. A systematic approach of energy field integration and optimization is proposed. Finally, representative processes are reviewed to highlight some principles of Intelligent EFM.

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Kaikko, Juha, Lasse Koskelainen, Jari L. H. Backman, and Jaakko Larjola. "Optimal Design of a Heat Exchanger for an Externally-Fired Microturbine in Combined Heat and Power Generation." In ASME Turbo Expo 2008: Power for Land, Sea, and Air. ASMEDC, 2008. http://dx.doi.org/10.1115/gt2008-51244.

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Biofuels have a vital role in emerging distributed energy systems. Special interest is focused on heat engines that can utilize biomass by direct combustion, such as externally-fired microturbines (EFMT). This paper considers a case where a natural gas-fired microturbine is converted into an EFMT. In the application the combustion chamber is replaced by a metallic heat exchanger retrofitted into a large biomass-fueled hot water boiler. The hot air that leaves the microturbine is directed into the furnace as preheated combustion air. In the paper, techno-economical optimization is performed for the selected heat exchanger configuration. The optimization is based on maximizing the net present value of the investment. The optimum depends on the cost of the new components and the resulting effect on the overall plant performance. The results show that the energy prices have only a mild impact on the optimum dimensions, although the feasibility of the investment itself depends strongly on the economy parameters. Using the optimized heat exchanger, the performance of the EFMT is predicted under part-load conditions of the boiler.

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Tiandong Zhao, Tianjiao Li, Minwoo Nho, and Xiaofang Zhou. "Bit stream compression using Self-Adaptive EFDR coding." In 2016 13th IEEE International Conference on Solid-State and Integrated Circuit Technology (ICSICT). IEEE, 2016. http://dx.doi.org/10.1109/icsict.2016.7998775.

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Herrmann, S., M. Götzberger, M. Blöchinger, and M. Dollhopf. "„Endoscopic full-thickness resection“ (eFTR): Eine unizentrale retrospektive Analyse über Effektivität der eFTR für komplexe kolorektale Läsionen, insbesondere als Therapie des kolorektalen Frühkarzinoms." In 46. Jahrestagung der Gesellschaft für Gastroenterologie in Bayern e.V. Georg Thieme Verlag KG, 2018. http://dx.doi.org/10.1055/s-0038-1648592.

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Zhang, Wenwu. "Review of Intelligent Energy Field Manufacturing (EFM)." In ASME 2008 International Manufacturing Science and Engineering Conference collocated with the 3rd JSME/ASME International Conference on Materials and Processing. ASMEDC, 2008. http://dx.doi.org/10.1115/msec_icmp2008-72541.

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The long cycles of modern economy is driven by technology innovations. New methodologies are needed to increase the efficiency of technology innovations. Intelligent Energy Field Manufacturing is one of such methodologies. The evolution and the fundamentals of Intelligent Energy Field Manufacturing (EFM) are reviewed in this paper. One issue in technology innovation is that the importance of manufacturing process innovations is underestimated. The other issue is how and why shall manufacturing Go Green to increase long-term sustainability. These should be the important topics in the research of Intelligent EFM.

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Mo, Hongjia, Michael Peter Kennedy, Vincent O'Brien, and Brendan Mullane. "Experimental validation of DAC with nested bus-splitting EFM4 DDSM." In 2013 European Conference on Circuit Theory and Design (ECCTD). IEEE, 2013. http://dx.doi.org/10.1109/ecctd.2013.6662198.

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Reports on the topic "EFMR"

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Dodd, Hope, David Peitz, Gareth Rowell, Janice Hinsey, David Bowles, Lloyd Morrison, Michael DeBacker, Jennifer Haack-Gaynor, and Jefrey Williams. Protocol for Monitoring Fish Communities in Small Streams in the Heartland Inventory and Monitoring Network. National Park Service, April 2021. http://dx.doi.org/10.36967/nrr-2284726.

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Fish communities are an important component of aquatic systems and are good bioindicators of ecosystem health. Land use changes in the Midwest have caused sedimentation, erosion, and nutrient loading that degrades and fragments habitat and impairs water quality. Because most small wadeable streams in the Heartland Inventory and Monitoring Network (HTLN) have a relatively small area of their watersheds located within park boundaries, these streams are at risk of degradation due to adjacent land use practices and other anthropogenic disturbances. Shifts in the physical and chemical properties of aquatic systems have a dramatic effect on the biotic community. The federally endangered Topeka shiner (Notropis topeka) and other native fishes have declined in population size due to habitat degradation and fragmentation in Midwest streams. By protecting portions of streams on publicly owned lands, national parks may offer refuges for threatened or endangered species and species of conservation concern, as well as other native species. This protocol describes the background, history, justification, methodology, data analysis and data management for long-term fish community monitoring of wadeable streams within nine HTLN parks: Effigy Mounds National Monument (EFMO), George Washington Carver National Monument (GWCA), Herbert Hoover National Historic Site (HEHO), Homestead National Monument of America (HOME), Hot Springs National Park (HOSP), Pea Ridge National Military Park (PERI), Pipestone National Monument (PIPE), Tallgrass Prairie National Preserve (TAPR), and Wilson's Creek national Battlefield (WICR). The objectives of this protocol are to determine the status and long-term trends in fish richness, diversity, abundance, and community composition in small wadeable streams within these nine parks and correlate the long-term community data to overall water quality and habitat condition (DeBacker et al. 2005).

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