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Journal articles on the topic "EGX-1"

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Soliman, Walid Shehata. "The Moderating Effect of Firm Characteristics on the Association Between Accounting Conservatism and Cash Holdings." International Journal of Accounting and Financial Reporting 9, no. 4 (October 11, 2019): 385. http://dx.doi.org/10.5296/ijafr.v9i4.15887.

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Recent studies are interested in the determinants of cash holdings (CASH), some of these studies focus on conservatism, as one of these determinants. In light of a debate on the nature of the association between conservatism and CASH, this paper discusses and investigates the answers for three questions, the first question about the direct association between conservatism and CASH, the second question about the moderating effect of firm characteristics on this association, the third question about the effect of adopting Egyptian Accounting Standards (EAS) since 2016 on the last association. This paper focuses on Egyptian listed firms in Egyptian Stock Exchange (EGX), especially EGX 100, for six years period from 2013 to 2018 for 11 main sectors, 125 firms and 703 unbalances panel data observations. The findings indicate that (1) conservatism has a negative effect on CASH, (2) only firm size has a moderating and positive effect on the association between conservatism and CASH, (3) firm leverage, firm growth opportunity, and firm managerial ownership do not have a moderating effect on the last association. (4) Adopting EAS in 2016 by Egyptian listed firms gives the management of these firms' suitable chances to control CASH using its association with conservatism.
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Sainan, Khairul Imran, Naqiuddin Arsyad, Mohd Ezzuan Salleh, and Firdaus Mohamad. "Development of 1:1 and 2:1 Channel Ratio Bipolar Plates (BPPs) for PEMFC." Applied Mechanics and Materials 799-800 (October 2015): 105–9. http://dx.doi.org/10.4028/www.scientific.net/amm.799-800.105.

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Proton Exchange Membrane Fuel Cell (PEMFC) is a device that generates electricity through an electrochemical reaction of oxygen air and hydrogen fuel. Thetransportofoxidantand fuel through the bipolarplatesis a significant factor affecting the cell performance. Currently, present work concentrates highly on flow field layout and channels design configurations. In this paper, the development two flow field layouts are discussed with different inlet/outlet channel ratio. Serpentine-paralleldesignisusedasthe base layout. The flow fields have inlet/outlet channel ratio of 1:1 and multiple inlet 2:1 configurations. Graphite is used as theplate material.Theanodeflowchannelis 2 mmx 1.2 mmx 2 mm meanwhile the cathode channel is 2 mm x 0.5 mm x 2 mm fora xbxwrespectively.Theactiveareais 25 cm2 with 5 cmx 5 cm dimensions. The fields were fabricated by Roland EGX-360 Desktop Engraver machine that involved drilling and profiling process. The fuel cell assembly process is explained in detail. The gasketmaterialis made from two materials which are Polyimide and Silicon. A series of pre-conditioning experiments were carried out in both fuel cells for confident purposes.
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Shehata, Walid, and Ahmed Rashed. "Accounting Conservatism, Information Asymmetry and Cash Holdings." Journal of Accounting, Business and Management (JABM) 28, no. 1 (June 14, 2021): 63. http://dx.doi.org/10.31966/jabminternational.v28i1.826.

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This paper focuses on explore the association between accounting conservatism and cash holding through a mediating effect of information asymmetry (IA) for Egyptian firms listed in EGX 100 within the period between 2013 -2018 through 124 firms with 703 firm-observations. The results indicates that (1) conservatism doesn’t have an enormous effect on information asymmetry, (2) information asymmetry doesn’t have a serious effect on cash holding, (3) there’s not any mediation role of information asymmetry within the relationship between conservatism and cash, (4) conservatism effect a negatively on cash holding
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Shaker, Mohamed A., and Marwan M. Abdeldayem. "Examining asset pricing models in emerging markets: Evidence from Egypt." Corporate Ownership and Control 16, no. 1 (2018): 50–57. http://dx.doi.org/10.22495/cocv16i1art6.

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The study aims at executing five tantamount asset pricing models in Egypt, in particular: 1) “the CAPM”, 2) “the Fama-French three-factor model (1993)”, 3) “the Carhart model (1997)”, 4) “the four-factor model of Chan and Faff (2005)”, and 5) “the five-factor model (Liquidity and Momentum-Augmented Fama-French three factor model)”. This research effort pursues Fama-French arranging approach in view of the size and Book-to-Market proportion (B-M ratio) for 55 securities out of the most 100 stocks in the Egyptian Stock Exchange (EGX) over a five years’ time period. We utilized “the time series regression of Black, Jensen and Scholes (1972)”. The findings of the study revealed that in terms of predictability, FF three-factor model prompts a significant improvement over the CAPM, while alternate models do not demonstrate a noteworthy increment over the FF three factor model.
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Abd-Alla, Mustafa Hussein, and Mahmoud Sobh. "Empirical Test of Fama and French Three-Factor Model in the Egyptian Stock Exchange." Financial Assets and Investing 11, no. 2 (December 31, 2020): 5–18. http://dx.doi.org/10.5817/fai2020-2-1.

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We test the empirical validity of the three-factor model of Fama and French in the Egyptian Stock Exchange (EGX) using monthly excess stock returns of 50 stocks listed on the EGX from January 2014 to December 2018. Our findings do not support Fama and French three-factor model, where the coefficient of the beta was insignificant. The “SBM” coefficient and the “HML” coefficient were equal to zero and insignificant, which confirms the absence of the small firm effect and book-to-market ratio effect in the market. We conclude that there is no relation between expected return and Fama-French risk factors.
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Abd-Alla, Mustafa Hussein, and Mahmoud Sobh. "Empirical Test of Fama and French Three-Factor Model in the Egyptian Stock Exchange." Financial Assets and Investing 11, no. 2 (December 31, 2020): 5–18. http://dx.doi.org/10.5817/fai2020-2-1.

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We test the empirical validity of the three-factor model of Fama and French in the Egyptian Stock Exchange (EGX) using monthly excess stock returns of 50 stocks listed on the EGX from January 2014 to December 2018. Our findings do not support Fama and French three-factor model, where the coefficient of the beta was insignificant. The “SBM” coefficient and the “HML” coefficient were equal to zero and insignificant, which confirms the absence of the small firm effect and book-to-market ratio effect in the market. We conclude that there is no relation between expected return and Fama-French risk factors.
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Wagdi, Osama, Amira Hasaneen, and Madyha Metwally. "The Impact of Executive Management on Internal Auditing Quality Under the Agency's Problem: Evidence From Egypt." International Journal of Accounting and Financial Reporting 9, no. 4 (October 11, 2019): 41. http://dx.doi.org/10.5296/ijafr.v9i4.15498.

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The study provides a framework for determinants of an impact of Executive Management on internal auditing quality according to eight dimensions (1) leadership style of executive management, (2) Organizational Culture, (3) operation cost of internal auditing, (4) providing information and disclosure for internal auditor (5) cooperation and facilitation from executive management (6) the attitude of executive management of earnings management, (7) the attitude of executive management for creative accounting and (8) professional ethics of executive management. The population of the study is Egyptian manufacturing firms listing at EGX and their employees. Accordingly, the number of received questionnaires was 392 from 28 firms in the first half of 2019 but the financial reports for 2018. The study found the impact of executive management on internal auditing quality, and it is significant at 0.01 level. According to adjusted R-squared; executive management interprets (97.1%) of an internal auditing quality level. Finally; the current framework of corporate governance need to take into organizational characteristics, as well as the ethical and behavioural variables, with than further controls on the Board of Directors, as well as ensuring the independence of internal audit to maximize the quality of internal audit.
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Elewa, May. "Firm Performance and Market Behavior during First Wave of COVID-19 in Egypt: Panel Data Analysis." Asian Journal of Finance & Accounting 13, no. 2 (July 12, 2021): 1. http://dx.doi.org/10.5296/ajfa.v13i2.18846.

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The purpose of this paper is to identify the impact of market capital MC and net profit NP on stock price SP and trade volume (TV) in the developing Egyptian business context. This study collects data from 29 non-financial organizations registered on the EGX 30 during the 6 month, 1/1/2020 to 30/6/2020, lockdown in Egypt due to the first wave of COVID-19. Data for the monthly confirmed cases and death cases of COVID-19 are collected for the 6 months of the study and compared to the monthly records of closing prices and trade volume in Egyptian poundsEGP. The study population represents 174 firm year observations. The firms studied operate in cash, have annual financial reports during the period 1/1 to 31/12, obtain complete financial data, and have not been eliminated all throughout the study. In this work the pooled model, the fixed effects model, and the random effects model are used.SPSSis applied to achieve the required statistical analysis. The study is a panel data analysis. Outcomes demonstrate existing substantial effects between market capital MC and stock price SP during the first wave of COVID-19. However, no significant effect is evident of the market capital MC and net profit NP with the trade volume TV during the first wave of this pandemic. This literature is advantageous for external and internal stakeholders and regulatory bodies. The study is a modest contribution that may help boost the business processes to reach better financial performance in times of unexpected catastrophes.
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Laukova, A., M. Pogany Simonova, I. Kubasova, S. Gancarcikova, I. Placha, J. Scerbova, V. Revajova, R. Herich, M. Levkut Sn, and V. Strompfova. "Pilot experiment in chickens challenged with Campylobacter jejuni CCM6191 administered enterocin M-producing probiotic strain Enterococcus faecium CCM8558 to check its protective effect." Czech Journal of Animal Science 62, No. 11 (October 9, 2017): 491–500. http://dx.doi.org/10.17221/12/2017-cjas.

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Campylobacter jejuni is one of the most common food-borne pathogens and chickens are the main source of these bacteria. Enterococcus faecium AL41, enterocin M-producing strain (deponed to the Czech Culture Collection of Microorganisms, Brno, Czech Republic – CCM8558) is our isolate previously applied e.g. in broiler rabbits with beneficial effect. In this study it was used in a 11-day experiment with chickens (1-day-old, breed Cobb 500, n = 40) challenged with C. jejuni. Birds had free access to feed and water; they were randomly divided into four groups per 10 chicks each: control (CG), E. faecium CCM8558 (EG1), CCM8558 + C. jejuni CCM6191 (EG2), CCM6191 (EG3). E. faecium CCM8558 (10<sup>9 </sup>CFU/ml, 200 µl) in Ringer solution was administered daily per os to EG1 and EG2 for 7 days (from day 0–1). EG3 and EG2 were infected individually per os (day 4, CCM6191, 10<sup>8</sup> CFU/ml in Ringer solution, 200 µl). For microbiota evaluation, faecal mixtures (n = 5) were sampled on day 0–1 (1<sup>st</sup> sampling), on day 7 (2<sup>nd</sup> sampling), and on day 11 (3<sup>rd</sup> sampling) (day 7 of CCM8558 application, day 4 post-infection; day 4 of CCM8558 cessation, day 7 post-infection). Five birds from each group were sacrificed. CCM8558 sufficiently colonized chickens. In faeces of EG2 a tendency to reduce Campylobacter spp. (day 7 of application, day 4 of infection) was noted compared to EG2 (day 11, day 4 of cessation, day 7 post-infection; difference 1.21 log cycles), while in EG3 CCM6191 strain was not reduced. Phagocytic activity (PA) values were significantly higher in infected groups compared to CG and EG1. A significant increase in PA was also noted in EG2 and EG3 at the end of experiment compared to CG or EG1. The strain additive did not evoke oxidative stress. Biochemical parameters were influenced to the reference levels.
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Kovacik, A., M. Gasparovic, E. Tvrda, K. Tokarova, E. Kovacikova, M. Rolinec, L. Rumanova, M. Capcarova, and B. Galik. "Effects of humic acid diet on the serum biochemistry and oxidative status markers in pheasants." Veterinární Medicína 65, No. 6 (June 26, 2020): 258–68. http://dx.doi.org/10.17221/174/2019-vetmed.

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This study investigated the effect of different concentrations of humic acids (HAs) on the selected serum biochemistry parameters and oxidative status markers in common pheasants (Phasianus colchicus). The control birds were fed a diet with no HA additives, while the birds in the experimental groups were fed diets containing HAs at the level of 0.5% (EG1), 0.75% (EG2) and 1.0% (EG3) from 1 to 90 days of age. The blood sodium concentration decreased (P &lt; 0.01) in the group fed by 1.00% HAs compared to the control birds. The concentration of potassium in the EG2 group increased (P &lt; 0.05) in comparison to the control group. The EG1 group showed a higher (P &lt; 0.01) serum glucose than the EG2 group. Significant differences (P &lt; 0.05; P &lt; 0.01) were also found between the experimental groups (EG1 vs EG2, and EG2 vs EG3) in the cholesterol concentrations. The birds in the experimental groups showed lower ROS (reactive oxygen species) and MDA (malondialdehyde) production. An opposite effect was observed in the TAC (total antioxidant capacity), where its values significantly increased in the experimental groups. The diet supplementation affected the enzymatic antioxidant system of the fattened pheasants, and so the HAs exhibited an antioxidant potential in these birds.
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Dissertations / Theses on the topic "EGX-1"

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Debiparshad, Kevin. "Musculoskeletal phenotype of Egr-1 deficient mice." Thesis, McGill University, 2010. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=86749.

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Early growth response protein-1 (EGR-1) is a transcription factor induced by stress or injury, mitogens, and differentiation factors. It has been shown to be regulated by various cytokines, growth factors and by ischemic/hypoxic stress as well as shear stress and mechanical injury. These regulators have been linked to both the development as well the degeneration of the musculoskeletal system, namely articlar cartilage, intervertebral discs (IVDs) and bone. Furthermore, Egr-1 has been shown to regulate the expression of collagens and enzymes affecting the extracellular matrix. Polymorphisms of DNA binding sites for EGR-1 have shown to be associated with both disc degeneration and osteoporosis. The aim of this study was to determine the affects of EGR-1 deficiency on articular cartilage, IVD and bone phenotype.
Wild-type (+/+) C57Bl/6 or Egr-1-deficient (−/−) mice were sacrificed at the same age interval (8- to 9-months). Standard histological preparation and staining with Safranin-O/Fast Green were done. Also immuncohistochemistry was performed using anti-bodies to type X collagen, cleavage products of both type II collagen and aggrecan. Imaging of mice was with plain radiographs, bone mineral density measurements and microCT analysis.
Results revealed that these mice have differences including abnormal bone structure and density, structural and possibly compositional differences in articular cartilage and structural and biochemical changes in IVDs. This points to the importance of Egr-1 in the maintenance of normal bone, IVD and articular cartilage and makes it a possible target for initiating pathological conditions of these tissues.
La protéine de croissance EGR-1 (Early Growth Response protein-1, en anglais) est un facteur de transcription qui est induit par la tension ou la blessure, les facteurs mitogènes, et les facteurs de différenciation. EGR-1 est ainsi régulé par divers cytokines, facteurs de croissance, par les conditions ischémique, ainsi que la tension et les blessures mécaniques. Ces régulateurs ont été reliés au développement ainsi que la dégradation du système squeletto-musculaire, particulièrement le cartilage articulaire, les disques intervertébraux (DIV) et l'os. De plus, il a été démontré que EGR-1 peut réguler l'expression des collagènes et d'enzymes contribuant à la matrice extracellulaire. Le polymorphisme de séquences d'ADN pour les des sites d'attachements d'EGR-1 a démontré être associé avec la dégradation de disques intervertébraux et l'ostéoporose. L'objectif de cette étude était de déterminer l'effet d'une expression réduite d'EGR-1 sur les phénotypes du cartilage articulaire, les DIV, et l'os.
Les souris C57Bl/6 de phénotype sauvage (+/+) ou ceux avec une expression réduite d'EGR-1 (−/−) ont été sacrifiées au même intervalle d'âge (8 à 9 mois). La préparation histologique standard et la coloration avec Safranin-O/Fast Green a été fait. Aussi l'immunohistochimie a été exécuté avec des anticorps pour le collagène de type X, et les produits de clivage du collagène de type II ainsi que les aggrécanes. L'imagerie de souris a été faite avec les radiographies simples, les mesures de densité minéraux de l'os, et avec l'analyse de micro-tomodensitomètre.
Les résultats ont révélé que ces souris ont des différences incluant la structure et densité d'os anormaux, les différences structurelles et possiblement compositionnelles dans le cartilage articulaire, et les changements structurels et biochimiques dans les DIV. Ceci indique à l'importance d'EGR-1 dans l'entretien d'os normal, des DIV et le cartilage articulaire, et le rend une cible possible pour initier les conditions pathologiques de ces tissus.
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Owen, Jo. "Structural and functional studies of fibulin-1 EGF domains." Thesis, University of Oxford, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.270656.

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Maifrede, Silvia. "EGR-1 TUMOR SUPPRESSOR IN BCR-ABL DRIVEN LEUKEMIA." Diss., Temple University Libraries, 2015. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/321048.

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Molecular Biology and Genetics
Ph.D.
Chronic Myelogenous Leukemia (CML) is a hematological disease originated with a chromosomal translocation t(9;22)(q34;q11) in a pluripotent hematopoietic stem cell. CML typically evolves in 3 different clinical phases: chronic and accelerated phases, and blast crisis. Disease progression is associated with the acquisition of secondary mutations that can be of very diverse origins, including inactivation of tumor suppressor genes, as well as inhibition of differentiation, DNA repair and telomere maintenance. While current therapies are very often successful, the remaining issues of resistance and the fact that therapy will not cure CML make it important that new therapy capable of effectively curing it be developed. The early growth response-1 (Egr-1) gene is a zinc-finger transcription factor localized to the human chromosome 5. Egr-1 belongs to a family of early response genes whose expression is rapidly stimulated by growth factors, hormones and neurotransmitters. In addition, Egr-1 is a myeloid differentiation primary response (MYD) gene, and is a positive regulator of terminal myeloid differentiation that potentiates macrophage differentiation. It also has been shown that Egr-1 plays a role in the development, growth control and survival of several cell types, such as T cells, B cells, and neuronal cells in addition to myeloid cells. There is a large amount of evidence consistent with Egr-1 behaving as a tumor suppressor in hematopoietic cells, both in vivo & in vitro, in both humans & mice, making it a prime candidate for a role in CML. In this study we asked if Egr-1 would behave as a tumor suppressor in CML. To answer that we investigated the function of Egr-1 in BCR-ABL driven leukemia using a mouse m bone marrow transplantation (BMT) model. We observe that loss of Egr-1 accelerates the onset of BCR-ABL driven CML. Furthermore, through Facs analysis we showed that most animals developed myeloid leukemia, determined by the observation that the majority of GFP+ cells in the BM were positive for Gr-1 and negative for B220. Interestingly a small cohort of mice developed B-cell acute lymphoid leukemia (B-ALL); this included both WT BCR-ABL and Egr-1 KO BCR-ABL BM-transplanted groups. In addition, we demonstrated that the loss of Egr-1 caused a more aggressive leukemia, which resulted not only in more rapid onset of disease but also greater enlargement of spleen and liver, as well as a tendency to more aggressive lung infiltration of leukemic cells. We also showed that decreased apoptosis, increased proliferation rates and resulting increased viability are consistent with, and probably contribute to, the increased leukemic potential of Egr-1 KO BCR-ABL BM. In addition, we demonstrated that Egr-1 expression was downregulated in BCR-ABL expressing BM cells in vitro, and in spleens of transplanted leukemic mice. Moreover, a very interesting observation, consistent with the rapid onset and aggression of disease, was that the bone marrow of leukemic mice caused by Egr-1 KO BCR-ABL BM transplantation, were enriched with lineage negative BCR-ABL-expressing cells, significantly more so than what was observed in WT BCR-ABL-transplanted mice. That this is also an enrichment of leukemia initiating cells was demonstrated using bone marrow from primary transplantation in a secondary bone marrow transplantation assay. Furthermore, using serial replating assays of colony forming units (CFUs), it was demonstrated that Egr-1 KO BCR-ABL-expressing BM had higher self-renewal ability than WT BCR-ABL-expressing BM, exhibiting an enrichment of primitive stem cells and fewer differentiated cells relative to WT counterparts. Finally, we also analyzed expression of Egr-1 in samples of CML human patients; the results are intriguing but due to small sample size inconclusive. Further inquiry on Egr-1 in CML, including expanding the study of human CML, signaling analysis, interaction of Egr gene family members in leukemia, and gain of function experiments should identify novel players that can impact on the aggressiveness of the disease, predict outcome for currently established therapies, as well identify targets for treatment regimens or adjunct therapy. In addition, these studies can provide a paradigm for understanding how Egr-1 functions as a tumor suppressor for other cancers and types of leukemia, and also delineate pathways that can be activated/inhibited by drugs, including reactivating Egr-1 expression.
Temple University--Theses
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Hashim, Irshaad. "The Effect of Freud-1/CC2D1A Knockout on EGF Receptor Activation." Thesis, Université d'Ottawa / University of Ottawa, 2015. http://hdl.handle.net/10393/33400.

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CC2D1A (coiled-coil and C2 domain containing protein 1A), also known as Freud-1, has been identified as a transcriptional repressor of the serotonin receptor 5-HT1A, a regulator of endosomal budding and an activator of NF-KB signaling. It also acts as a scaffold that promotes activity of the PI3K/Akt pathway upon stimulation by the epidermal growth factor (EGF). Moreover, several studies highlight naturally occurring mutations of CC2D1A in humans that produce varying degrees of intellectual disorder and autism. Use of the Cre-LoxP system to conditionally knockout CC2D1A in mice has provided promising results regarding its effect on 5-HT1A expression and behaviour. This thesis aims to extend the use of this knockout model by studying cell signaling activity in mouse embryonic fibroblasts (MEFs), derived from the CC2D1Aflx/flx transgenic line, that have been treated with a commercially available Cre recombinase to completely knock out CC2D1A. I hypothesize that CC2D1A directly regulates EGF receptor activity and that its Cre-mediated knock down in vitro will entirely block cell signaling pathways activated by the EGF receptor. Western blot analysis demonstrated that, after Cre-mediated CC2D1A knockout, Akt and Erk1/2 phosphorylation were still maintained upon EGF treatment. In addition, overexpressing Freud-1 via transfection had no effect on cell signaling compared to the wild-type control. Analysis of recombinant Freud-1 constructs reveal that a C-terminal truncation enhances its ability to bind to PIP2 and PIP3 – phospholipids essential to the Akt pathway. In addition, immunocytochemistry analysis demonstrates a responsiveness of CC2D1A to EGF treatment. Altogether, these data highlight a unique and effective way in carrying out gene knockout in vitro while also emphasizing the need to further investigate CC2D1A’s importance in regulating cell signaling pathways and functional compensation by other homologous proteins
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Gallagher, Ewen. "The regulation of the egr-1 promoter in B cell lines." Thesis, University of Nottingham, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.341970.

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Lee, Jeffrey Robson. "Mechanism of Drosophila EGF receptor activation by Rhomboid-1 and Star." Thesis, University of Cambridge, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.619660.

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Kasneci, Amanda. "Early growth factor response 1 (Egr-1) negatively regulates expression of calsequestrin (CSQ) on cardiomyocytes in vitro." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=112521.

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Heart failure represents an important cause of death in Western Countries. The pathophysiology of heart failure is mainly associated with abnormalities in intracellular calcium control. We previously showed that Egr-1 negatively regulates expression of sodium-calcium exchanger (NCX) in vivo and in vitro. Here we tested the hypothesis that Egr-1 regulates expression of calcium storage proteins in the sarco-endoplasmic reticulum (SER), calsequestrin (CSQ) and/or ER, calreticulin (CRT) directly or indirectly via Egr-1:NFAT (nuclear factor of activated T-cells) formation. Secondarily, we hypothesized that this will reduce calcium mobilization. We found that undifferentiated 1293F cells, overexpressing Egr-1, have reduced CSQ compared to control H9c2 cells. We demonstrated that Egr-1 negatively regulates CSQ but not CRT expression. The Egr-1 mediated decrease in CSQ is linked to decreased calcium availability. Repression is by a novel NAB-independent (NGFI-A binding protein) activity localized to a.a. region 1-307. We conclude that Egr-1-mediated reductions in calcium storage protein expression alter calcium availability for cardiac contraction/relaxation.
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Shao, Zhiyong. "Roles of Caenorhabditis elegans EGL-9 in HIF-1 regulation and pathogen resistance." [Ames, Iowa : Iowa State University], 2010. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3403833.

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Messai, Habib. "Insulin-like growth factor I (IGF-I), Epidermal growth factor (EGF), Endothéline-1 (ET-1) et vieillissement des chrondrocytes articulaires." Paris 7, 2001. http://www.theses.fr/2001PA077101.

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LIMA, Jacqueline de Souza. "Diversidade Genética e estrutura espacial intrapopulacional em Tibouchina papyrus(POHL) Toledo utilizando marcadores microssatélites." Universidade Federal de Goiás, 2011. http://repositorio.bc.ufg.br/tede/handle/tde/2555.

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Made available in DSpace on 2014-07-29T16:21:16Z (GMT). No. of bitstreams: 1 Dissertacao Jacqueline (final).pdf: 503234 bytes, checksum: cbbe7d056e9c71e1218bf7062ca9a262 (MD5) Previous issue date: 2011-02-25
Tibouchina papyrus is a Melastomataceae endemic to the Cerrado. It has a disjunct distribution, restricted to campos rupestres . Therefore, it can be considered a model species, helping guide Cerrado endemic plant studies. Thus, this study aimed to characterize genetic variability in microsatellite regions of T. papyrus genome and use spatial statistical analysis methods to assess genetic diversity and structure in disjunct populations. Individuals were georeferenced and leaf samples were taken from the localities of Serra dos Pirineus (216), Serra Dourada (66) and Serra de Natividade (192). In order to obtain the genotypes, we used ten microsatellite loci that were developed for T. papyrus. The locus showed a mean of 3,4 alleles and a large number of private alleles was detected (19 in total) at the populations studied. Values (f) significant were observed for two populations, indicating that populations not are following the proportions expected by Hardy-Weinberg. The global  value is significant and equal to 0.712, showing a high differentiation among the three populations studied. Thus, the three populations of T. papyrus can be treated as three different ESUs. Spatial genetic structure was weak for two populations, with low levels of SP. The low SGS corroborates the hypothesis that wind-dispersed species present no SGS due to long distance gene flow because of seed dispersal. This is plausible for T. papyrus, which is a wind-dispersed species. Despite the low intra-population SGS found in two populations, based on the relationship between kinship and distance, significant positive values were observed for the some distance class, indicating higher values for the relationship between these individuals. The intercept of the correlogram for each population may indicate the minimum distance where it is more likely that sampled individuals are less similar, which is an information applicable for the management of T. papyrus populations. Based on genetic data, it was evident that the three T. papyrus populations must be preserved, because each one contains a number of unique genetic variability that is not shared between them. Thus, theoretically it is possible to maintain the evolutionary potential of this species and to avoid local extinction in only three regions where it occurs.
Tibouchina papyrus é uma Melastomataceae endêmica do Cerrado que possui distribuição disjunta e restrita aos campos rupestres, com essas características peculiares ela pode ser considerada modelo de espécie, auxiliando em estudos de outras plantas do Cerrado que exibem o mesmo conjunto de características. Neste sentido, o objetivo desse trabalho foi caracterizar a variabilidade genética existente em regiões microssatélites do genoma de T. papyrus e utilizar metodologias de análise estatística espacial para avaliar a diversidade e a estrutura genética nas três subpopulações disjuntas da espécie. Foram amostradas folhas e georreferenciados indivíduos nas Serras dos Pirineus (216) Serra Dourada (66) e Serra de Natividade (192). Para a obtenção dos genótipos foram utilizados dez locos microssatélites desenvolvidos para a espécie. Os dez locos produziram uma média de 3,4 alelos e foi detectado um grande número de alelos privados (19 no total) nas três subpopulações avaliadas. Foi observados valores de (f) significativos em duas subpopulações, indicando que estas subpopulações não estão seguindo as proporções esperadas para o equilíbrio de Hardy-Weinberg. O valor global de θ foi significativo e igual a 0,712, apresentando uma altíssima divergência genética entre as subpopulações. Sendo assim, as três subpopulações de T. papyrus podem ser tratadas como três diferentes ESUs. A estrutura genética espacial intrapopulacional apresentou-se fraca em duas subpopulações, com baixos níveis de SP. A existência de autocorrelação espacial pouco intensa corrobora com a hipótese de que espécies com dispersão pelo vento não exiba esta estrutura, em função do fluxo gênico causado pela dispersão de sementes em longas distâncias. Isso é plausível para T. papyrus, que apresenta dispersão por anemocoria. Apesar da fraca EGE intrapopulacional encontrada em duas subpopulações, baseado nos correlogramas de parentesco, foram observados valores positivos e significativos nas primeiras classes de distância, indicando um maior grau de parentesco entre esses indivíduos. O intercepto do correlograma para cada uma das subpopulações pode indicar o distanciamento mínimo onde é mais provável amostrar indivíduos menos semelhantes, que é uma informação relevante para o manejo das subpopulações da espécie T. papyrus. Com base nos dados genéticos obtidos ficou evidente que as três subpopulações da espécie T. papyrus devem ser conservadas, pois cada uma contém uma quantidade de variabilidade genética única que não é compartilhada entre elas. Sendo assim, teoricamente torna-se possível a manutenção do potencial evolutivo da espécie e evita a extinção local nas três únicas regiões de ocorrência natural da espécie.
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Books on the topic "EGX-1"

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Környei, István. Katonasors 1.: Egy honvéd naplója. Pomáz: Kráter, 2007.

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Garaczi, László. Mintha élnél: Egy lemúr vallomásai, 1. Pécs: Jelenkor, 1995.

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1% [egy százalék]: "forintszavazatok" civil szervezetekre : tanulmányok. Budapest: Nonprofit Kutatócsoport, 2000.

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Alter Ego 1 Alter Ego. Hachette Fle, 2006.

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Maxwell, Janetta. 1+1+1=1: God and the Egg. Trilogy Christian Publishing, Inc., 2022.

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Maxwell, Janetta. 1+1+1=1: God and the Egg. Trilogy Christian Publishing, Inc., 2022.

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Albasini, Mario, Maria Cristina Raimundo, and Maria Josefina Moreno. Firulete 1 Grado - 1 Ciclo Egb. Metodos, 1996.

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Parra, Cecilia, and Irma Saiz. Hacer Matematica 1 - 1 Ciclo Egb. Tandem Library, 1999.

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Edb. Religion Catolica 1 - 1 Ciclo Egb. Edebe, 1999.

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Castro, Marcela. Garrapinadas 1 - 1: Ciclo Egb / Anillado. AZ Editores, 2000.

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Book chapters on the topic "EGX-1"

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Nishio, Shunsuke, and Tsukasa Matsuda. "Fertilization 1: Sperm–Egg Interaction." In Advances in Experimental Medicine and Biology, 91–103. Singapore: Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-3975-1_6.

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Vogt, P. M., D. Wagner, M. Lehnhardt, V. Janssen, M. Marikowsky, E. Eriksson, and H. U. Steinau. "Die Wachstumsfaktoren heparinbindendes EGF (HB-EGF) und Insulin-like Growth Factor-1 (IGF-1) wirken synergistisch auf die Keratinozytenproliferation." In Chirurgisches Forum ’97 für experimentelle und klinische Forschung, 523–26. Berlin, Heidelberg: Springer Berlin Heidelberg, 1997. http://dx.doi.org/10.1007/978-3-642-60717-2_105.

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Oder, Johannes, Hermann Rottengruber, Christian Wouters, Marco Günther, and Stefan Pischinger. "CNG-DI-Engine at λ = 1-Operation with Highload-EGR." In Proceedings, 353–76. Wiesbaden: Springer Fachmedien Wiesbaden, 2021. http://dx.doi.org/10.1007/978-3-658-33521-2_25.

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Damm, Andreas. "Verhältnis von Art. 92 Abs. 1 EGV zu Art. 90 Abs. 2 EGV im Hinblick auf die Gebührenfinanzierung." In Schriftenreihe der Juristischen Fakultät der Europa-Universität Viadrina Frankfurt (Oder), 75–76. Berlin, Heidelberg: Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-642-72089-5_9.

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Hofmann, J., H. Kreis, R. Hackenberg, and K. D. Schulz. "Wachstumsregulation von Mammakarzinomzellen in vitro durch EGF, IGF-1 und IGF-2." In Gynäkologie und Geburtshilfe 1990, 242–43. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-76124-9_137.

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Strowitzki, T., R. Wiedemann, R. Kimmig, and H. Hepp. "Einfluß von EGF, IGF-1 und Wachstumshormon auf endometriale Stromazellen in vitro." In Gynäkologie und Geburtshilfe 1990, 1015–16. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-76124-9_528.

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Pfeiffer, Annette. "Das Rahmenprogramm (Art. 166 Abs. 1, Abs.2 EG)." In Veröffentlichungen des Instituts für Deutsches, Europäisches und Internationales Medizinrecht, Gesundheitsrecht und Bioethik der Universitäten Heidelberg und Mannheim, 85–118. Berlin, Heidelberg: Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/978-3-642-55642-5_6.

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Rössler, Oliver G., Luisa Stefano, Inge Bauer, and Gerald Thiel. "Stimulus-Transcription Coupling in the Nervous System: The Zinc Finger Protein Egr-1." In Transcription Factors in the Nervous System, 379–95. Weinheim, FRG: Wiley-VCH Verlag GmbH & Co. KGaA, 2006. http://dx.doi.org/10.1002/3527608036.ch18.

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Adamson, Eileen D., and Steven A. Edwards. "Oncogenes in Development: C-FOS and EGR-1 Studies in Embryonal Carcinoma Cells." In Uterine and Embryonic Factors in Early Pregnancy, 205–18. Boston, MA: Springer US, 1991. http://dx.doi.org/10.1007/978-1-4615-3380-1_17.

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Fernandez, M. L., and C. J. Andersen. "1. The good egg, the forgotten benefits: protein, carotenoids, choline and glycemic index." In Handbook of eggs in human function, 15–34. The Netherlands: Wageningen Academic Publishers, 2015. http://dx.doi.org/10.3920/978-90-8686-804-9_1.

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Conference papers on the topic "EGX-1"

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Zhang, Chao, Yan-Ping Wu, Jiao-Fei Cao, Yun Zhao, Zhi-Hua Chen, and Hua-Hao Shen. "Egr-1 regulates muc5ac expression through activator protein-1 (AP-1) in chronic airway inflammation diseases." In Annual Congress 2015. European Respiratory Society, 2015. http://dx.doi.org/10.1183/13993003.congress-2015.pa916.

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Cabot, G., M. Calbry, P. Xavier, A. Vandel, S. de Persis, B. Belaissaoui, E. Favre, and L. Pillier. "Effect of CO2 Capture on Combined Cycle Gas Turbine Efficiency Using Membrane Separation, EGR and OEA Effects on Combustion Characteristics." In ASME Turbo Expo 2014: Turbine Technical Conference and Exposition. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/gt2014-25781.

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In an energetic world of fossil fuel, there is a need to reduce the CO2 emission released to the atmosphere. CO2 Capture and Sequestration (CCS) is one of the solutions. To optimize the CO2 capture cost, thermodynamic cycles of power plants have to be modified, and resulting new designs inevitably lead to new combustion modes [1][2][3]. CO2 capture of post combustion gases can be performed using membrane processes, but its efficiency is interesting only if the CO2 concentration in the combustion process exhaust gases is higher than 30% [4]. Unfortunately, in classical combustion processes (e.g. gas turbine), diluted Exhaust Gases (EG) contain no more than 5 % of CO2 because combustion products are strongly diluted in air. Our objective consists in increasing the EG CO2 concentration, by using both Oxygen-Enriched Air (OEA) combustion and exhaust gas recirculation (EGR). Our approach is based on numerical simulations and on experimental work. First, operating parameters which minimize the CO2 capture cost are calculated and compared with the reference capture cost [5] (achieved by amine absorption of CO2). In parallel, experiments and additional calculations are performed in order to check the quality and the operability of such combustion mode. This paper is organized as follows: the first part presents the optimization of a new thermodynamic GTCC cycle, using OEA and EGR to increase EG CO2 concentration and capturing it in post-combustion with membrane separator. The effects of pressure and membrane selectivity will be studied in terms of CO2 capture cost, avoided CO2, implemented membrane surface, EGR rate and OEA quality. The second part is dedicated to the experimental and calculation [6] studies of combustion met in this type of configuration. A premixed swirl flame is fed first with Air, CH4 and CO2, then with OEA, CH4 and EGR. To neglect the thermal aspect of NOx production, measurements are performed at constant adiabatic flame temperature. The flame structure, combustion instability and pollutant emissions are presented as a function of the EGR rate dilution.
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Rongyan Yue, Chao Liu, Jingjing Xie, Changhu Xue, and Yuqian Han. "Study on the removal of cholesterol from Sthenoteuthis oualaniensis egg powder by subcritical 1, 1, 1, 2-tetrafluoroethane (R134a)." In 2011 International Conference on Remote Sensing, Environment and Transportation Engineering (RSETE). IEEE, 2011. http://dx.doi.org/10.1109/rsete.2011.5966271.

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Sang Hoon Jeong, Hwa Jung Ryu, Yoon-Hee Park, Hyun Cheol Bae, and Sang Wook Son. "Egr-1 expression induced by ZnO nanoparticles in human keratinocytes." In 2012 IEEE 12th International Conference on Nanotechnology (IEEE-NANO). IEEE, 2012. http://dx.doi.org/10.1109/nano.2012.6321932.

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Lee, S., H. Kim, and AM Choi. "Egr-1-Dependent Autophagy Inhibits the Development of Pulmonary Arterial Hypertension." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a1814.

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Rao, Rekha M., Amar Kumar, Pratikkumar Vekaria, Abdulraheem Yacoub, Barry Skikne, and Joseph McGuirk. "Abstract 2046: Egr-1 promotes bone marrow fibrosis in primary myelofibrosis." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-2046.

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Rao, Rekha M., Amar Kumar, Pratikkumar Vekaria, Abdulraheem Yacoub, Barry Skikne, and Joseph McGuirk. "Abstract 2046: Egr-1 promotes bone marrow fibrosis in primary myelofibrosis." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-2046.

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Shintake, Jun, Samuel Rosset, Bryan Schubert, Stefano Mintchev, Dario Floreano, and Herbert R. Shea. "DEA for soft robotics: 1-gram actuator picks up a 60-gram egg." In SPIE Smart Structures and Materials + Nondestructive Evaluation and Health Monitoring, edited by Yoseph Bar-Cohen. SPIE, 2015. http://dx.doi.org/10.1117/12.2084043.

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Reifarth, S., E. Kristensson, J. Borggren, A. Sakowitz, and H. E. Angstrom. "Analysis of EGR/Air Mixing by 1-D Simulation, 3-D Simulation and Experiments." In SAE 2014 International Powertrain, Fuels & Lubricants Meeting. 400 Commonwealth Drive, Warrendale, PA, United States: SAE International, 2014. http://dx.doi.org/10.4271/2014-01-2647.

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"Chemotherapeutic agent cisplatin suppresses stabilin-1-mediated clearance of EGF by tumor-associated macrophage." In Bioinformatics of Genome Regulation and Structure/ Systems Biology. institute of cytology and genetics siberian branch of the russian academy of science, Novosibirsk State University, 2020. http://dx.doi.org/10.18699/bgrs/sb-2020-290.

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Reports on the topic "EGX-1"

1

Sultanov, Marianna Z., and Mansoor M. Ahmed. EGR-1 Functional Activation, Signaling, and Radiation Response in Prostate Cancer. Fort Belvoir, VA: Defense Technical Information Center, April 2005. http://dx.doi.org/10.21236/ada438336.

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Ahmed, Mansoor M. Role of Early Growth Response-1 (Egr-1) Gene in Radiation-Induced Apoptosis of Prostate Cancer Cells. Fort Belvoir, VA: Defense Technical Information Center, May 2001. http://dx.doi.org/10.21236/ada398097.

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DE Belle, Ian. Cloning and Characterization of Active Egr-1 Target Genes by In Vivo Crosslinking. Fort Belvoir, VA: Defense Technical Information Center, May 2001. http://dx.doi.org/10.21236/ada395170.

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DE Belle, Ian. Cloning and Characteristics of Active Egr-1 Target Genes by In Vivo Crosslinking. Fort Belvoir, VA: Defense Technical Information Center, May 2003. http://dx.doi.org/10.21236/ada417973.

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DE Belle, Ian. Cloning and Characteristics of Active Egr-1 Target Genes by in Vivo Crosslinking. Fort Belvoir, VA: Defense Technical Information Center, December 2003. http://dx.doi.org/10.21236/ada424047.

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DE Belle, Ian. Cloning and Characterization of Active Egr-1 Target Genes by In Vivo Crosslinking. Fort Belvoir, VA: Defense Technical Information Center, May 2000. http://dx.doi.org/10.21236/ada382458.

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El Halawani, Mohamed, and Israel Rozenboim. Temperature Stress and Turkey Reproduction. United States Department of Agriculture, May 2002. http://dx.doi.org/10.32747/2002.7570546.bard.

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High temperature stress is of major concern to turkey producers in Israel and the United States. The decline in the rate of egg production at high environmental temperature is well recognized, but the neuroendocrinological basis is not understood. Our objectives were: 1) to characterize the hypothalamo-hypophyseal axis involvement in the mechanism(s) underlying the detrimental effect of heat stress on reproduction, and 2) to establish procedures that alleviate the damaging effect of heat stress on reproduction. Heat stress (40oC, Israel; 32oC, U.S.) caused significant reduction in egg production, which was restored by VIP immunoneutralization. The decline in egg production did not appear to be entirely related to the expression of incubation behavior due to the rise in circulating PRL in stressed birds. Heat stress was found to increase circulating PRL in ovariectomized turkeys independent of the reproductive stage. Active immunization against VIP was shown for the first time to up-regulate LHb and FSHb subunit mRNA contents. These findings taken together with the results that the heat stress-induced decline in egg production may not be dependent upon the reproductive stage, lead to the suggestion that the detrimental effect of heat stress on reproductive performance may be in part mediated by VIP acting directly on the GnRH/gonadotropin system. Inhibin (INH) immunoneutralization has been shown to enhance FSH secretion and induces ovulation in mammals. It is hypothesized that immunization of heat-stressed turkeys against INH will increase levels of circulating FSH and the number of preovulating follicles which leads to improved reproductive performance. We have cloned and expressed turkey INH-a and INH-bA. Active immunization of turkey hens with rtINH-a increased pituitary FSH-b subunit mRNA and the number of non-graded preovulatory yellow follicles, but no significant increase in egg production was observed.
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SUN, JUNJIANG, GUOPING QIAN, Shuqi Yue, and Anna szumilewicz. Factors influencing physical activity in pregnant women from the perspective of a socio-ecological model: A systematic review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, November 2022. http://dx.doi.org/10.37766/inplasy2022.11.0073.

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Review question / Objective: The main aim of this review is to analyse the impact factors of material physical activity in an ecological model and to analyse differences in influencing factors between pregnant women's PA and moderate-to-vigorous intensity physical activity (MVPA) , provide a reference for the research, intervention, and policy designation of maternal physical activity. Rationale: In combination with McLeroy et al. (1988)behavior is viewed as being determined by the following: (1) Personal level: the internal factors of the individual characteristics,(sociodemographic and biological, behavior, psychological ); (2) interpersonal level: interpersonal processes and primary groups-formal and informal social network and social support systems,(eg: family、public, etc.); (3)organization level: social institutions with organizational characteristics, such as health services, gyms and may also include influences from health care providers and Physical activity consultant, etc.; (4) community level: relationships among organizations, institutions, and informal networks within defined boundaries,(eg: appropriate facilities、living environment, etc.); and finally (5) public policy level: local, state, and national laws and policies.
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Moscatello, David K. Epidermal Growth Factor (EGF) Receptor Intron 1 CA Repeat Polymorphisms in African-American and Caucasian Males: Influence on Prostate Cancer Risk or Disease Progression and Interaction With Androgen Receptor CAG Repeat Polymorphisms. Fort Belvoir, VA: Defense Technical Information Center, September 2002. http://dx.doi.org/10.21236/ada410564.

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Liu, Miao, Hongan Wang, Jing Lu, Zhiyue Zhu, Chaoqun Song, Ye Tian, Xinzhi Chen, et al. Vitamin D supplementation in the treatment of Myasthenia Gravis A protocol for a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, September 2022. http://dx.doi.org/10.37766/inplasy2022.9.0129.

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Review question / Objective: The patients should meet the internationally recognized diagnostic criteria for myasthenia gravis and be definitely diagnosed as myasthenia gravis, excluding MG patients caused by congenital, drug and other factors, as well as patients with serious primary diseases, autoimmune diseases or mental diseases. Patients are not restricted by race, region, gender, age, background, course of disease and other factors. We will focus on trials using vitamin D as an intervention at any dose and in any regimen (eg daily/weekly/monthly intake). The control group was routinely given western medicine, including cholinesterase inhibitors, glucocorticoids, immunosuppressants, alone or in combination, or placebo. The intervention group was treated with vitamin D on the basis of western medicine treatment in the control group. The specific dosage form and dose were not limited, and the shortest course of treatment should be 4 weeks. Main outcome measures: (1) Quantitative score of myasthenia gravis (QMG); (2) Recurrence rate; (3) Effective. Secondary outcome measures: (1) The level of serum acetylcholine receptor antibody (AchRab); (2) The levels of inflammatory factors such as IL-6 and IL-10; (3) Clinical absolute score; (4) TCM syndrome score scale; (5) Quality of life score (QOL); (6) Incidence rate of adverse events. All randomized controlled trials (RCT) literatures from the establishment to September 2022 were retrieved and classified.
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