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Journal articles on the topic 'Ehrlich’s ascites tumour'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Sharmila K.P., Shilpa S. Shetty, Suchetha Kumari, Madhyastha Harishkumar, Ashwini Prabhu, and Satheesh Kumar Bhandary B. "Oroxylum indicum stem bark extract exerts antitumor potential against Ehrlich’s ascites carcinoma in Swiss albino mice." Biomedicine 42, no. 4 (2022): 686–92. http://dx.doi.org/10.51248/.v42i4.1559.

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Introduction and Aim: Constant efforts are exerted to explore unique bioactive principles from natural sources that possess more effective and specific antineoplastic activities. In the present study, we aimed to evaluate the antitumor activity of stem bark extract of Oroxylum indicum in mice bearing Ehrlich ascites carcinoma (EAC). Materials and Methods: Ninety female Swiss albino mice were categorized into fifteen groups (n=6). The animals were inoculated with 1x106 EAC cells. Tumor control animals received sterile water once daily for 10 consecutive days. Positive control group was injected

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Popov, Alexander, Anna Klimovich, Olga Styshova, et al. "Probable Mechanisms of Doxorubicin Antitumor Activity Enhancement by Ginsenoside Rh2." Molecules 27, no. 3 (2022): 628. http://dx.doi.org/10.3390/molecules27030628.

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Ginsenoside Rh2 increases the efficacy of doxorubicin (DOX) treatment in murine models of solid and ascites Ehrlich’s adenocarcinoma. In a solid tumor model (treatment commencing 7 days after inoculation), DOX + Rh2 co-treatment was significantly more efficacious than DOX alone. If treatment was started 24 h after inoculation, the inhibition of tumor growth of a solid tumor for the DOX + Rh2 co-treatment group was complete. Furthermore, survival in the ascites model was dramatically higher for the DOX + Rh2 co-treatment group than for DOX alone. Mechanisms underlying the combined DOX and Rh2 e

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Starkov, A. K., and N. M. Titova. "Targeted delivery of cisplatin conjugates with arabinogalactan to tumor using aptamers." Siberian Medical Review, no. 5 (2022): 107. http://dx.doi.org/10.20333/25000136-2022-5-107.

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The effectiveness of targeted delivery of cisplatin conjugate with arabinogalactan to ascitic Ehrlich carcinoma in vivo using the target ligand, the AS42 aptamer, was studied in this work. Studies conducted on male ICR mice with ascitic Ehrlich carcinoma. Antitumor therapy was carried out with cisplatin and an arabinogalactan-platinum complex (AG-Pt) and an AG-Pt complex modified with aptamers to ascitic Ehrlich carcinoma cells. The toxicity of drugs was determined on the basis of biochemical parameters of blood in healthy mice after 5-fold administration. In our studies, cisplatin treatment o

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4

Wojciak, E., and W. Korohoda. "Ehrlich ascites tumour cells show tissue-specific adherence and modify their shape upon contact with embryonic fibroblasts and myotubes." Journal of Cell Science 97, no. 3 (1990): 433–38. http://dx.doi.org/10.1242/jcs.97.3.433.

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Adhesiveness of Ehrlich ascites tumour (EAT) cells to glass, to mouse peritoneal membrane, living and aldehyde-fixed mouse embryo fibroblasts and chick embryo fibroblasts, myoblasts and myotubes was investigated. The ascitic EAT cells (and leukaemia L1210 cells) did not adhere to glass and peritoneum but readily adhered to embryo fibroblasts, myoblasts and myotubes. The attachment was followed by cell spreading and migration. Fixation of fibroblasts or myogenic cells with aldehydes did not prevent ascitic cells from attaching but reduced the rate of spreading. Only direct interaction of asciti

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Zamay, S. S., V. S. Prokopenko, K. A. Lukyanenko, and A. E. Sokolov. "Nanoscalpel based on magnetic discs and aptamers effectively and targeted destroy tumor cell." Siberian Medical Review, no. 2 (2021): 79–82. http://dx.doi.org/10.20333/25000136-2021-2-79-82.

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The aim of the research. To investigate the antitumor effi cacy of three-layer magnetic nanodiscs (Au / Ni / Au) with a quasi-dipole structure, functionalized with biorecognizing molecules of a tumor. Material and methods. Th ree-layer magnetic nanodiscs (Au / Ni / Au) 500 nm in size (were obtained by micro- and nanoelectronic technologies. Aptamers to ascites cells of Ehrlich carcinoma were used to functionalize magnetic nanodiscs. Th iol groups were used to bind disks to aptamers. As a model of tumor cells Ehrlich’s ascites carcinoma cells were used, and the cells were magnetically infl uenc

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6

KunduSen, Sriparna, Malaya Gupta, Upal K. Mazumder, Pallab K. Haldar, Prerona Saha, and Asis Bala. "Antitumor Activity of Citrus maxima (Burm.) Merr. Leaves in Ehrlich's Ascites Carcinoma Cell-Treated Mice." ISRN Pharmacology 2011 (April 19, 2011): 1–4. http://dx.doi.org/10.5402/2011/138737.

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Context. The plant Citrus maxima Merr. (Rutaceae), commonly known as shaddock or pomelo is indigenous to tropical parts of Asia. The objective of present study is to evaluate the methanol extract of Citrus maxima leaves for its antitumor activity against Ehrlich's Ascites Carcinoma cell in Swiss albino mice. Experimental design. The antitumor activity of methanol extract of Citrus maxima leaves (MECM) was evaluated against Ehrlich Ascites Carcinoma (EAC) cell line in Swiss albino mice. 2 × 106 cells were inoculated in different groups of animals. MECM (200 and 400 mg/kg BW i.p.) was administer

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LOBO, Carolina, Miguel A. RUIZ-BELLIDO, Juan C. ALEDO, Javier MÁRQUEZ, Ignacio NÚÑEZ DE CASTRO, and Francisco J. ALONSO. "Inhibition of glutaminase expression by antisense mRNA decreases growth and tumourigenicity of tumour cells." Biochemical Journal 348, no. 2 (2000): 257–61. http://dx.doi.org/10.1042/bj3480257.

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Phosphate-activated glutaminase has a critical role in tumours and rapidly dividing cells and its activity is correlated with malignancy. Ehrlich ascites tumour cells transfected with the pcDNA3 vector containing an antisense segment (0.28 kb) of rat kidney glutaminase showed impairment in the growth rate and plating efficiency, as well as a shortage in the glutaminase protein and activity. The C-terminal segment used is well conserved in all glutaminase sequences known. The transfected cells, named 0.28AS-2, displayed remarkable changes in their morphology compared with the parental cell line

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8

SALGADO, Flávio L. L., Ricardo ARTIGIANI-NETO, and Gaspar de Jesus LOPES-FILHO. "GROWTH FACTORS AND COX2 IN WOUND HEALING: AN EXPERIMENTAL STUDY WITH EHRLICH TUMORS." ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo) 29, no. 4 (2016): 223–26. http://dx.doi.org/10.1590/0102-6720201600040003.

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ABSTRACT Background: Healing is an innate biological phenomenon, and carcinogenesis acquired, but with common humoral and cellular elements. Carcinogenesis interferes negatively in healing. Aim: To evaluate the histological changes in laparotomy scars of healthy Balb/c mice and with an Ehrlich tumor in its various forms of presentation. Methods: Fifty-four mice were divided into three groups of 18 animals. First group was the control; the second had Ehrlich tumor with ascites; and the third had the subcutaneous form of this tumor. Seven days after tumor inoculation, all 54 mice were submitted

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9

Rudel, Alena E., Tatiana A. Filatenkova, and Maria S. Zharkova. "Activity of protegrin-1 against mouse Ehrlich ascites carcinoma <i>in vitro</i> and <i>in vivo</i>." Medical academic journal 24, no. 2 (2024): 117–24. http://dx.doi.org/10.17816/maj631421.

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BACKGROUND: The problem of multidrug resistance in cancer treatment creates an urgent demand for developing new effective antitumor agents. Due to the unusual mechanism of recognizing and damaging tumor cells, antimicrobial peptides are considered as possible prototypes for designing such therapeutics. AIM: This work was aimed to compare the antitumor potential of the promising membranolytic antimicrobial peptide protegrin-1 in vitro and in vivo in Ehrlich ascites carcinoma mice model. MATERIALS AND METHODS: We used two variants of the model by inducing a tumor in solid or ascites form. In the

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Jaganathan, Saravana Kumar, Dilip Mondhe, Z. A. Wani, Harish C. Pal, and Mahitosh Mandal. "Effect of Honey and Eugenol on Ehrlich Ascites and Solid Carcinoma." Journal of Biomedicine and Biotechnology 2010 (2010): 1–5. http://dx.doi.org/10.1155/2010/989163.

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Ehrlich ascites carcinoma is a spontaneous murine mammary adenocarcinoma adapted to ascites form and carried in outbred mice by serial intraperitoneal (i/p) passages. The previous work from our laboratory showed that honey having higher phenolic content was potent in inhibiting colon cancer cell proliferation. In this work, we extended our research to screen the antitumor activity of two selected honey samples and eugenol (one of the phenolic constituents of honey) against murine Ehrlich ascites and solid carcinoma models. Honey containing higher phenolic content was found to significantly inh

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11

Kalinina, T. S., A. A. Shimshirt, K. V. Lisitskaya, A. V. Volkova, and N. V. Kudryashov. "Study of diazepam effects on Ehrlich ascites carcinoma and anxiety responses in male SHK mice." Pharmacokinetics and Pharmacodynamics, no. 1 (May 1, 2022): 20–29. http://dx.doi.org/10.37489/2587-7836-2022-1-20-29.

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Сomorbidity of malignant tumors and affective disorders is an urgent problem. It is known that some psychotropic drugs may adversely influence the growth of malignant tumors and metastasis; in the experiment, a connection between neurotransmitters and tumors was established. Earlier, in experiments on mice, the ability of diazepam to stimulate the growth of Ehrlich's ascites carcinoma was demonstrated. The aim of this study was to assess the role of central and peripheral benzodiazepine receptor sites in the stimulating effect of diazepam on Ehrlich's carcinoma. The effects of diazepam (0.03 a

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Bandyopadhyay, Chandrakana, Alak Manna, Soumita De, et al. "Anti-tumor effect of fruit rind of Myristica malabarica in an Ehrlich ascites carcinoma model." International Journal of Basic & Clinical Pharmacology 8, no. 3 (2019): 383. http://dx.doi.org/10.18203/2319-2003.ijbcp20190648.

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Background: Among the various modalities of anti-cancer treatment, cancer chemotherapy plays a very vital role. The alarming side effects being its main drawback leads to relentless research for newer agents. A new natural agent with promising anti-cancer properties from in-vitro studies leads to this study. Here we have evaluated the anti-tumor activity of a crude extract of fruit rind of Myristica malabarica in an Ehrlich ascites carcinoma model in mice.Methods: A murine model of cancer was established with i.p. inoculation of Ehrlich Ascites carcinoma (EAC) cells; animals were divided into

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Joseph, Soniamol, Baby Sabulal, Varughese George, Kuttikkadan Antony, and Kainoor Janardhanan. "Antitumor and anti-inflammatory activities of polysaccharides isolated from Ganoderma lucidum." Acta Pharmaceutica 61, no. 3 (2011): 335–42. http://dx.doi.org/10.2478/v10007-011-0030-6.

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Antitumor and anti-inflammatory activities of polysaccharides isolated fromGanoderma lucidumIn this study, polysaccharides were isolated fromGanoderma lucidum (Polyporaceae)and their antitumor and anti-inflammatory activities were investigated usingin vivomodels. Potential antitumor activity was shown byG. lucidumpolysaccharides (GLP) against solid tumor induced by Ehrlich's ascites carcinoma cells. GLP at 100 mg kg-1body mass showed 80.8 and 77.6 % reduction in tumour volume and tumour mass, respectively, when administered 24 h after tumour implantation. Again, GLP at the same dose but when a

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Liju, V. B., K. Jeena, and R. Kuttan. "CYTOTOXICITY, ANTITUMOUR AND ANTICARCINOGENIC ACTIVITY OF CURCUMA LONGA ESSENTIAL OIL." INDIAN DRUGS 51, no. 03 (2014): 28–34. http://dx.doi.org/10.53879/id.51.03.p0028.

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In the present study, we have evaluated the antitumour and anticarcinogenic activity of turmeric essential oil in vivo. Turmeric essential oil was found to have significant in vitro cytotoxic activity against Dalton’s lymphoma ascites cells (DLA) and Ehrlich ascites carcinoma (EAC) cancer cell lines. Concentration needed for 50% cytotoxicity (IC50) was 8 μg for DLA cells and 18 μg to EAC cell lines. Oral administration of turmeric essential oil was found to significantly increase the life span (56.25%) of Dalton’s Lymphoma Ascites (DLA) induced ascites tumour bearing mice as well as significan

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Samoylenko, О. А., Yu M. Samchenko, L. О. Kernosenko, et al. "INPACT OF LAPONITE ON ENZYME ACTIVITY AND REDOX STATE OF THE TUMOR AND ORGANS OF THE DETOXIFICATION SYSTEM OF MICE WITH EhRLICH CARCINOMA." Oncology 26, no. 2 (2024): 125–32. http://dx.doi.org/10.15407/oncology.2024.02.125.

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Summary. Laponite (Lap) is a synthetic clay mineral represented by disk-shaped nanoplatelets. The Lap (native or acid-activated) can be used for encapsulation of medical compounds, in particular anticancer drugs. Aim: to study the levels of the rate of superoxide radical (SR) generation, the activity of ribonucleases (RNases), gelatinases and ornithine decarboxylase (ODK) in tumor cells, liver and kidneys of intact mice and mice with Ehrlich carcinoma under the influence of Lap. Objects and methods: the purified gel-forming native Lap of the XLG class with the empirical formula Si8Mg5.45Li0.4H

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Gardam, Michael A., Narciso R. Mejia, and Robert E. MacKenzie. "The NADP-dependent trifunctional methylenetetrahydrofolate dehydrogenase purified from mouse liver is immmunologically distinct from the mouse NADP-dependent bifunctional enzyme." Biochemistry and Cell Biology 66, no. 1 (1988): 66–70. http://dx.doi.org/10.1139/o88-008.

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Methylenetetrahydrofolate dehydrogenase – methenyltetrahydrofolate cyclohydrolase – formyltetrahydrofolate synthetase was purified to homogeneity from mouse liver, taking advantage of its very high affinity for 2′,5′-ADP-Sepharose. Antibodies raised to this trifunctional enzyme and to the bifunctional NAD-dependent dehydrogenase–cyclohydrolase from mouse Ehrlich ascites tumour cells were found not to cross-react with the purified proteins on Western blots. Each of these polyclonal antibodies detects the appropriate protein in extracts of Ehrlich ascites tumour cells after sodium dodecyl sulfat

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Ujjani, B., G. Krakower, G. Bachowski, S. Krezoski, C. F. Shaw, and D. H. Petering. "Host zinc metabolism and the Ehrlich ascites tumour. Zinc redistribution during tumour-related stress." Biochemical Journal 233, no. 1 (1986): 99–105. http://dx.doi.org/10.1042/bj2330099.

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Zinc redistribution between plasma and liver has been examined in mice injected with Ehrlich-ascites-tumour cells. Within 24 h of injection plasma Zn levels decrease and Zn appears in newly synthesized liver metallothionein. This response is dependent upon the number of tumour cells injected into the host. Uptake of Zn into liver and its specific accumulation in a Zn-binding protein, identified as metallothionein, continues for a number of days and reaches a plateau as tumour growth ceases. Over this time period, plasma copper rises. This redistribution also occurs in mice pretreated with cadm

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18

Parry, E. W. "Fatal susceptibility to cycloheximide of mice bearing Ehrlich ascites tumours and of animals pretreated with cell-free Ehrlich ascites tumour fluid." Journal of Comparative Pathology 99, no. 3 (1988): 309–15. http://dx.doi.org/10.1016/0021-9975(88)90051-5.

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A, Prameela Rani, Agarjuna Babu E, Prem Madhur S, Ravi Chandra Sekhara Reddy D, and Phani Kumar K. "EVALUATION OF ANTICANCER ACTIVITY OF PARKINSONIA ACULEATA LEAVES EXTRACT ON EHRLICH’S ASCITES CARCINOMA-INDUCED MICE." Asian Journal of Pharmaceutical and Clinical Research 11, no. 1 (2018): 390. http://dx.doi.org/10.22159/ajpcr.2017.v11i1.22404.

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Objective: The objective of the study was to investigate the anticancer activity of the ethanolic extract of Parkinsonia aculeata (EEPA) leaves. Methods: Anticancer activity of P. aculeata (EEPA) of leaf extract was evaluated in Swiss albino mice against Ehrlich ascites carcinoma (EAC) cell line at the doses of 200 and 400 mg/kg body weight orally. The extracts were administered for 14 consecutive days. 24 h of the last dose and 18 h of fasting, the mice were sacrificed, and the anticancer effect of EEPA was assessed by evaluating tumor volume, viable and nonviable tumor cell count, tumor weig

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A, Prameela Rani, Agarjuna Babu E, Prem Madhur S, Ravi Chandra Sekhara Reddy D, and Phani Kumar K. "EVALUATION OF ANTICANCER ACTIVITY OF PARKINSONIA ACULEATA LEAVES EXTRACT ON EHRLICH’S ASCITES CARCINOMA-INDUCED MICE." Asian Journal of Pharmaceutical and Clinical Research 11, no. 1 (2018): 390. http://dx.doi.org/10.22159/ajpcr.2018.v11i1.22404.

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Objective: The objective of the study was to investigate the anticancer activity of the ethanolic extract of Parkinsonia aculeata (EEPA) leaves. Methods: Anticancer activity of P. aculeata (EEPA) of leaf extract was evaluated in Swiss albino mice against Ehrlich ascites carcinoma (EAC) cell line at the doses of 200 and 400 mg/kg body weight orally. The extracts were administered for 14 consecutive days. 24 h of the last dose and 18 h of fasting, the mice were sacrificed, and the anticancer effect of EEPA was assessed by evaluating tumor volume, viable and nonviable tumor cell count, tumor weig

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Parry, E. W. "Hydrocortisone protects cycloheximide-challenged mice pretreated with Ehrlich ascites tumour cells or with cell-free Ehrlich ascites tumour fluid." Journal of Comparative Pathology 103, no. 3 (1990): 315–19. http://dx.doi.org/10.1016/s0021-9975(08)80052-7.

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Lambert, Ian Henry, Thomas Kjær Klausen, Andreas Bergdahl, Charlotte Hougaard, and Else Kay Hoffmann. "ROS activate KCl cotransport in nonadherent Ehrlich ascites cells but K+ and Cl− channels in adherent Ehrlich Lettré and NIH3T3 cells." American Journal of Physiology-Cell Physiology 297, no. 1 (2009): C198—C206. http://dx.doi.org/10.1152/ajpcell.00613.2008.

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Addition of H2O2 (0.5 mM) to Ehrlich ascites tumor cells under isotonic conditions results in a substantial (22 ± 1%) reduction in cell volume within 25 min. The cell shrinkage is paralleled by net loss of K+, which was significant within 8 min, whereas no concomitant increase in the K+ or Cl− conductances could be observed. The H2O2-induced cell shrinkage was unaffected by the presence of clofilium and clotrimazole, which blocks volume-sensitive and Ca2+-activated K+ channels, respectively, and is unaffected by a raise in extracellular K+ concentration to a value that eliminates the electroch

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Medina, Miguel Angel, and Ignacio Núñez de Castro. "Evidence of an Intracellular Dissipative Structure." Zeitschrift für Naturforschung C 43, no. 9-10 (1988): 793–94. http://dx.doi.org/10.1515/znc-1988-9-1027.

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Abstract Data are presented showing the result of the functioning of the mitochondrial respiratory chain in Ehrlich ascites tumour cells incubated with glucose and glutamine. The very different results obtained depending on the order of substrate addition suggest that the functioning of the respiratory chain in Ehrlich cells far-from-equilibrium maintains an intracellular dissipative structure.

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Kuttan, Ramadasan, Sivamurthy R. G., and Girija Kuttan. "POTENTIAL ANTI-TUMOR AND ANTI-INFLAMMATORY ACTIVITY OF SIX MISTLETOE PLANTS IN THE FAMILY VISCACEAE PRESENT IN WESTERN GHATS, INDIA." International Journal of Pharmacy and Pharmaceutical Sciences 9, no. 10 (2017): 57. http://dx.doi.org/10.22159/ijpps.2017v9i11.20541.

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ABSTRACTObjectivesTo find out the cytotoxicity, anti-tumor and anti-inflammatory activities of six species of plants belongs to Viscaeceae family available in Western Ghats (India).MethodsIn vitro cytotoxicity of Viscum extracts was studied by trypan blue exclusion method and MTT assay using various cell lines. Anti-tumor activity was determined using Ehrlich ascites carcinoma (EAC) and Dalton’s lymphoma ascites (DLA) cells in mice. Anti-inflammatory activities of Viscum extracts were studied using carrageenan and dextran induced mouse paw edema models in mice.ResultsAll six Viscaeceae plant e

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Ramalho, Rondon Tosta, Ricardo Dutra Aydos, and Marney Pascoli Cereda. "Evaluation of acetone cyanohydrin effect in "in vitro" inativation of the Ehrlich ascites tumor cells." Acta Cirurgica Brasileira 25, no. 1 (2010): 111–16. http://dx.doi.org/10.1590/s0102-86502010000100022.

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PURPOSE: To evaluate the antitumor effect of acetone cyanohydrin in Ehrlich ascites tumor cells in vitro. METHODS: The Ehrlich ascites tumor cells and lymphocytes were incubated with different concentrations of acetone cyanohydrin (0, 0.5, 1.0, 2.0, 10.0, 20.0 and 30.0 μg.mL-1), After 1, 2, 3, 4, 18 and 24 hours cell viability tests were performed by the trypan blue method. RESULTS: The results demonstrated a dose-dependent cytotoxic effect against the cells of Ehrlich ascites tumor. The concentrations of 20 and 30 μg.mL-1 was 100% of cell death in only 1 and 2 hours respectively. In lower dos

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Wojtczak, L. "The Crabtree effect: a new look at the old problem." Acta Biochimica Polonica 43, no. 2 (1996): 361–68. http://dx.doi.org/10.18388/abp.1996_4505.

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Inhibition of respiration by glucose, known as the Crabtree effect, has been observed in several tumours and some other highly glycolytic cells and tissues. Among mechanisms proposed to explain this effect were: competition between glycolysis and respiration for ADP or for inorganic phosphate, change of intracellular pH, change in the permeability of mitochondrial membranes, specific regulatory behavior of glycolytic enzymes, and specific enzyme topography within the cell. None of these proposals alone seems satisfactory. The present article describes the research carried out in the author's l

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Anghileri, Leopold J., and Jacques Robert. "Effects of Tumor Necrosis Factor on Tumor Cell Plasma Membrane Permeability." Tumori Journal 73, no. 3 (1987): 269–71. http://dx.doi.org/10.1177/030089168707300310.

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Ehrlich ascites tumor cells incubated with rabbit tumor necrosis factor (TNF)-serum showed a temperature-dependent functional impairment of the plasma membrane as reflected by permeability changes. Trypan blue inclusion and Ca2+-transport were considerably increased at hyperthermia temperature. This characteristic of the TNF-plasma membrane interaction may explain the cytotoxicity of TNF.

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Hernández, D., and M. De la Fuente. "Mannose toxicity in Ehrlich ascites tumor cells." Biochemistry and Cell Biology 67, no. 6 (1989): 311–14. http://dx.doi.org/10.1139/o89-048.

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Mannosephosphate isomerase (MPI) showed a higher activity than hexokinase (HKM) in its ability to phosphorylate mannose in the spleen, thymus, brain, liver, striated muscles, kidneys, and testes from BALB/c mice. This led to a HKM/MPI ratio of less than 1 in all the organs and tissues mentioned. In contrast, Ehrlich ascites tumor cells obtained from the peritoneum of BALB/c mice had low MPI activity (half of the HKM activity and, therefore, a ratio of 2). Mannose, which is nontoxic to nontumor cells at a concentration of 0.1 M, induced marked in vitro mortality of the tumor cells. Incubation o

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Inzhevatkin, E. V., and A. A. Savchenko. "The spatial metabolic heterogeneity of solid type of Ehrlich carcinoma." Доклады Академии наук 486, no. 5 (2019): 626–30. http://dx.doi.org/10.31857/s0869-56524865626-630.

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The NAD(P)-dependent dehydrogenase activity was studied in different fields of solid form of Ehrlich carcinoma. It was shown that there is a metabolic distinction between different fields of the solid tumor. In this way there is a significant difference between ascites and solid type of Ehrlich carcinoma.

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Lucius, R. W., I. D. Waddell, A. Burchell, and R. C. Nordlie. "The hepatic glucose-6-phosphatase system in Ehrlich-ascites-tumour-bearing mice." Biochemical Journal 290, no. 3 (1993): 907–11. http://dx.doi.org/10.1042/bj2900907.

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To examine the effects of the presence of Ehrlich ascites tumours on both the catalytic unit and the substrate/product translocase components of the glucose-6-phosphatase system in vivo, we isolated microsomes from the livers of control and tumour-bearing mice. Samples were analysed immunochemically for the quantity of catalytic unit, stabilizing protein and translocases T2 and T3 proteins. In comparison experiments, a variety of kinetic studies were performed. The most striking findings in tumour-bearing mice were: a 2.5-fold increase in the quantity of translocase T2 protein; increases in th

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Romanov, Yu A., and V. A. Stepanenko. "Chronobiological organization of reproduction of Ehrlich's ascites tumor cells." Bulletin of Experimental Biology and Medicine 100, no. 2 (1985): 1115–16. http://dx.doi.org/10.1007/bf00837405.

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32

Gstrein, E., M. Paulmichl, and F. Lang. "Electrical properties of Ehrlich ascites tumor cells." Pfl�gers Archiv European Journal of Physiology 408, no. 5 (1987): 432–37. http://dx.doi.org/10.1007/bf00585065.

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Sandhiya, V. "Allograft Model: An Pioneering Advance for In-Vivo Study." Journal of Advances in Drug Discovery and Development 1, no. 1 (2023): 15–18. https://doi.org/10.5281/zenodo.7911892.

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<em>The modeling of Ehrlich ascites carcinoma (EAC), one of the most common cancers, is crucial. EAC, also referred to as an undifferentiated carcinoma, is entirely malignant at the beginning, never regresses, highly transplantable, hyper diploid, proliferates swiftly, and has a reduced lifetime span. The tumor-specific transplantation antigen (TSTA) is likewise absent. The proliferation rate of malignant tumours frequently increases progressively as the tumor's virulence rises through successive passes. However, as the cells develop free growth control mechanisms, boost their hetero-trans

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Estrela, J. M., R. Hernandez, P. Terradez, M. Asensi, I. R. Puertes, and J. Viña. "Regulation of glutathione metabolism in Ehrlich ascites tumour cells." Biochemical Journal 286, no. 1 (1992): 257–62. http://dx.doi.org/10.1042/bj2860257.

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Glutathione metabolism was studied in cancer cells during the growth of an Ehrlich ascites tumour. GSH, but not GSSG, content decreases when cell proliferation and the rate of protein synthesis in the tumour decrease. This change correlates with a decrease in the rate of GSH synthesis and an increase in glutathione peroxidase and glutathione S-transferase activities. Glutathione efflux from tumour cells seems to co-ordinate with the rate of GSH synthesis. Cysteine, and not methionine, promotes GSH synthesis in tumour cells. However, changes in the rate of GSH synthesis are not due to limitatio

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Vieira, Juliana, Patricia Matsuzaki, Márcia Kazumi Nagamine, et al. "Inhibition of ascitic ehrlich tumor cell growth by intraperitoneal injection of Pfaffia paniculata (Brazilian ginseng) butanolic residue." Brazilian Archives of Biology and Technology 53, no. 3 (2010): 609–13. http://dx.doi.org/10.1590/s1516-89132010000300014.

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This study aimed to investigate the effects of the administration of butanolic residue (BR) of Pfaffia paniculata by intraperitoneal route to Ehrlich ascitis tumor bearing mice. Initially, a toxicity study of P. paniculata BR was performed in which doses of 12.5; 25 and 50mg/Kg were administered by intraperitoneal injection for seven days to Swiss mice. The treatment did not show toxicity. Then, Swiss male mice received, by intraperitoneal injection, once a day, 12.5; 25 or 50mg/Kg of P. paniculata BR for seven days. This protocol started in the same day of tumor inoculation with 5X10(6) cells

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Corrier, Donald E., and James O. Norman. "Effects of T-2 mycotoxin on tumor susceptibility in mice." American Journal of Veterinary Research 49, no. 12 (1988): 2147–50. https://doi.org/10.2460/ajvr.1988.49.12.2147.

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SUMMARY The effect of Fusarium-produced T-2 toxin on tumor growth was evaluated in ICR, CFW, and C57B6/6 mice inoculated with murine sarcoma, Ehrlich ascites carcinoma, or B16F1 melanoma tumor cell lines. Mice were given T-2 toxin intragastrically either at the rate of 2 mg of toxin/kg of body weight daily for 5 days or a single dosage of 4 mg of toxin/kg and were inoculated sc with tumor cells 1 or 2 days after administration of toxin. Tumor growth was assessed 15 to 41 days after tumor challenge by determining the frequency of tumor development and tumor weights. Significant increases in the

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Riquelme, Gloria, Francisco V. Sepúlveda, Finn Jørgensen, Susanne Pedersen, and Else K. Hoffmann. "Swelling-activated potassium currents of Ehrlich ascites tumour cells." Biochimica et Biophysica Acta (BBA) - Biomembranes 1371, no. 1 (1998): 101–6. http://dx.doi.org/10.1016/s0005-2736(98)00006-6.

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Nissler, Karl, Henning Petermann, Ingrid Wenz, and Dieter Brox. "Fructose 2,6-bisphosphate metabolism in Ehrlich ascites tumour cells." Journal of Cancer Research and Clinical Oncology 121, no. 12 (1995): 739–45. http://dx.doi.org/10.1007/bf01213320.

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Segura, J. A., M. A. Medina, F. J. Alonso, F. Sanchez-Jimenez, and I. Núñez De Castro. "Glycolysis and glutaminolysis in perifused ehrlich ascites tumour cells." Cell Biochemistry and Function 7, no. 1 (1989): 7–10. http://dx.doi.org/10.1002/cbf.290070103.

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Marathe, Gopal K., and Cletus J. M. D'Souza. "Production of oxygen free radicals by Ehrlich ascites tumour cells: effect of lipids." Mediators of Inflammation 2, no. 1 (1993): 53–57. http://dx.doi.org/10.1155/s0962935193000079.

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Phorbol-12-myristate-13-acetate (PMA), calcium ionophore A23187 and platelet activating factor (PAF) stimulated the generation of oxygen free radicals (nitro-blue tetrazolium reduction) in Ehrlich ascites tumour (EAT) cells. PAF was effective at an optimal concentration of 4 μM, but was inhibited by BN 52021, a specific PAF antagonist. Lyso-PAF was ineffective. Inclusion of different lipids during incubation prior to the addition of PAF, resulted in the activation/inhibition of free radical generation. Among the phospholipids at a concentration of 50 μg/ml, the order of activation was phosphat

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BODNAR, MAREK, and URSZULA FORYŚ. "THREE TYPES OF SIMPLE DDE'S DESCRIBING TUMOR GROWTH." Journal of Biological Systems 15, no. 04 (2007): 453–71. http://dx.doi.org/10.1142/s0218339007002313.

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In this paper, we compare three types of dynamical systems used to describe tumor growth. These systems are defined as solutions to three delay differential equations: the logistic, the Gompertz and the Greenspan types. We present analysis of these systems and compare with experimental data for Ehrlich Ascites tumor in mice.

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Zinchenko, V. P., V. V. Teplova, and Yu V. Evtodienko. "Membrane-bound Ca2+ in mitochondria of Ehrlich's ascites tumor cells." Bulletin of Experimental Biology and Medicine 100, no. 5 (1985): 1522–25. http://dx.doi.org/10.1007/bf00836153.

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Neves, Camila Lima, Christiano Marcello Vaz Barbosa, Priscila Andrade Ranéia-Silva, Eliana L. Faquim-Mauro, and Sandra Coccuzzo Sampaio. "Crotoxin Modulates Macrophage Phenotypic Reprogramming." Toxins 15, no. 10 (2023): 616. http://dx.doi.org/10.3390/toxins15100616.

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Macrophage plasticity is a fundamental feature of the immune response since it favors the rapid and adequate change of the functional phenotype in response to the pathogen or the microenvironment. Several studies have shown that Crotoxin (CTX), the major toxin of the Crotalus durissus terrificus snake venom, has a long-lasting antitumor effect both in experimental models and in clinical trials. In this study, we show the CTX effect on the phenotypic reprogramming of macrophages in the mesenchymal tumor microenvironment or those obtained from the peritoneal cavity of healthy animals. CTX (0.9 o

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Galcheva-Gargova, Zoya, and Lubomira Stateva. "Immunological identification of two lamina-like proteins in Saccharomyces cerevisiae." Bioscience Reports 8, no. 3 (1988): 287–91. http://dx.doi.org/10.1007/bf01115046.

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Proteins from Saccharomyces cerevisiae were tested for their crossreactivity with antibodies raised against nuclear lamina proteins of Ehrlich Ascites Tumour cells. The results of the immunoblotting experiments and ELISA suggest the existence of at least two proteins (65 and 59 kDa) which are immunologically related to the nuclear lamina proteins of higher eukaryotes.

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Idiz, Ufuk Oguz, Yurdakul Deniz Firat, Coskun Cakir, Emrah Yucesan, and Erhan Aysan. "Effects of Boric Acid on Ehrlich Ascites Tumor." Istanbul Medical Journal 19, no. 3 (2018): 251–54. http://dx.doi.org/10.5152/imj.2018.63549.

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Levinson, Charles. "Regulatory volume increase in Ehrlich ascites tumor cells." Biochimica et Biophysica Acta (BBA) - Biomembranes 1021, no. 1 (1990): 1–8. http://dx.doi.org/10.1016/0005-2736(90)90375-x.

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Hammond, J. R., and R. M. Johnstone. "Solubilization and reconstitution of a nucleoside-transport system from Ehrlich ascites-tumour cells." Biochemical Journal 262, no. 1 (1989): 109–18. http://dx.doi.org/10.1042/bj2620109.

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Uptake of [3H]uridine by Ehrlich cells was mediated by both nitrobenzylthioinosine (NBMPR)-sensitive (75%) and NBMPR-insensitive (25%) mechanisms. Each cell contained approx. 26,000 high-affinity (KD = 0.19 nM) recognition sites for [3H]NBMPR, and binding was inhibited by dipyridamole and adenosine at concentrations similar to those required for inhibition of [3H]uridine uptake. Calculations show that each cell contains a total of about 35,000 nucleoside transporters. Photoaffinity labelling of a partially purified preparation of plasma membranes with [3H]NBMPR resulted in a single broad 3H-la

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Santos, Orlando José dos, Euler Nicolau Sauaia Filho, Flávia Raquel Fernandes do Nascimento, et al. "Use of raw Euphorbia tirucalli extract for inhibition of ascitic Ehrlich tumor." Revista do Colégio Brasileiro de Cirurgiões 43, no. 1 (2016): 18–21. http://dx.doi.org/10.1590/0100-69912016001005.

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Objective: to evaluate the effect of the Euphorbia tirucalli hydroalcoholic extract (ETHE) on the development of Ehrlich Tumor, in its ascitic form. Methods: we intraperitoneally inoculated 15 Swiss mice with 10.44 x 107 cells of Ehrlich Tumor and divided them in two groups one day after: ETHE Group (eight mice), treated with a dosage of 125 mg/kg/day of EHTE for five days; and Control Group (seven mice), treated only with 0.9% isotonic saline solution over the same period. The treatment was done by gavage. Ten days after inoculation, four mice from each group were sacrificed for quantificatio

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Raju, A. B., Venu Gopal Y, Ravindranath A, Kalpana G, and Prabhakar Reddy V. "Antitumor Activity of Diospyros peregrina on Ehrlich Ascites Carcinoma in Mice." Journal of Scientific Research 3, no. 2 (2011): 413–19. http://dx.doi.org/10.3329/jsr.v3i2.6787.

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The methanol extract of Diospyros peregrina (Ebenaceae) bark (MEDP) were evaluated for antitumor activity against Ehrlich ascites carcinoma (EAC)-bearing swiss albino mice. The extract was administered at the doses of 200 and 400 mg/kg body weight per day for 14 days after 24 h of tumor inoculation. After the last dose and 18 h fasting, the mice were sacrificed. The present study deals with the effect of MEDP on the growth of transplantable murine tumor, life span of EAC-bearing hosts and hematological profile MEDP caused significant (P < 0.01) decrease in tumor volume, packed cell volume,

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Evans, P. M., D. K. Suker, and I. ap Gwynn. "Expression of anionic sites on tumour cells at different stages of tissue invasion in vivo: a comparative study by X-ray microanalysis." Journal of Cell Science 94, no. 3 (1989): 561–66. http://dx.doi.org/10.1242/jcs.94.3.561.

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Quantification of colloidal iron hydroxide (CIH) labelling by X-ray microanalysis was used to investigate anionic sites at the surface of Ehrlich carcinoma cells from different locations in the mouse host. Individual tumour cells from peritoneal ascites suspensions (pre-invasion stage) varied up to threefold in their ability to bind CIH and a similar degree of intra-tumour heterogeneity was observed in different experimental animals. Pretreatment of the cells with neuraminidase confirmed that binding was at least partly due to surface sialic acid. Invasive cells isolated from mesenteric tumour

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