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Journal articles on the topic 'Eisenmenger syndrome'

Author: Grafiati
Published: 4 June 2021
Last updated: 20 February 2023

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1

Campos, Fernando Peixoto Ferraz de, and Luiz Alberto Benvenuti. "Eisenmenger Syndrome." Autopsy and Case Reports 7, no. 1 (2017): 5–7. http://dx.doi.org/10.4322/acr.2017.006.

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2

Arvanitaki, Alexandra, Michael A. Gatzoulis, Alexander R. Opotowsky, Paul Khairy, Konstantinos Dimopoulos, Gerhard-Paul Diller, George Giannakoulas, et al. "Eisenmenger Syndrome." Journal of the American College of Cardiology 79, no. 12 (March 2022): 1183–98. http://dx.doi.org/10.1016/j.jacc.2022.01.022.

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3

Previte, Joseph, and Panchapakesan Haran. "Eisenmenger Syndrome." Seminars in Cardiothoracic and Vascular Anesthesia 5, no. 1 (March 2001): 67–78. http://dx.doi.org/10.1053/scva.2001.21556.

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4

Beghetti, Maurice, and Nazzareno Galiè. "Eisenmenger Syndrome." Journal of the American College of Cardiology 53, no. 9 (March 2009): 733–40. http://dx.doi.org/10.1016/j.jacc.2008.11.025.

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5

Duke, Martin. "Victor Eisenmenger (1864–1932): The man behind the syndrome." Journal of Medical Biography 25, no. 1 (July 9, 2016): 52–55. http://dx.doi.org/10.1177/0967772014555301.

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Although much has been written about the cardiovascular abnormalities present in Eisenmenger’s syndrome, little has been recorded previously in the medical literature about Victor Eisenmenger, the Austrian doctor whose name is attached eponymously to this disorder. Archival material together with information provided by his descendants and relatives has been gathered to make available further details of his life, family, schooling, medical training and accomplishments. An examination of Eisenmenger’s book about his observations and experiences while serving from 1895 to 1914 as personal physician to Archduke Francis Ferdinand, the heir presumptive to the Austro-Hungarian throne, also sheds light on Eisenmenger’s personality, abilities and interests.
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6

Thiene, Gaetano. "Eisenmenger Syndrome Revisited." World Journal for Pediatric and Congenital Heart Surgery 8, no. 6 (November 2017): 726–34. http://dx.doi.org/10.1177/2150135117727259.

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7

Marwali, Eva M., Novik Budiwardhana, and Anna U. Rahayoe. "Inhaled prostacyclin for Eisenmenger syndrome complicated with miliary tuberculosis." Paediatrica Indonesiana 51, no. 4 (August 30, 2011): 241. http://dx.doi.org/10.14238/pi51.4.2011.241-4.

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Eisenmenger syndrome occurs in patients with large congenital cardiac or extracardiac left-to-right shunts. Clinically, Eisenmenger syndrome is characterized by multiple organ involvement and progressive deterioration of function over time. In the advanced stages, signs and symptoms of Eisenmenger syndrome include central cyanosis, dyspnea, fatigue, hemoptysis, syncope and right-sided heart failure. Survival of patients with Eisenmenger syndrome is generally poor, but appears to be better than that of patients with idiopathic pulmonary arterial hypertension (PAH) in a comparable functional class.1
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8

Nashat, Heba, Aleksander Kempny, Colm McCabe, Laura C. Price, Carl Harries, Rafael Alonso-Gonzalez, Michael A. Gatzoulis, Stephen J. Wort, and Konstantinos Dimopoulos. "Eisenmenger syndrome: current perspectives." Research Reports in Clinical Cardiology Volume 8 (February 2017): 1–12. http://dx.doi.org/10.2147/rrcc.s117838.

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9

Jeyamalar, R., V. Sivanesaratnam, and P. Kuppuvelumani. "Eisenmenger Syndrome in Pregnancy." Australian and New Zealand Journal of Obstetrics and Gynaecology 32, no. 3 (February 13, 2008): 275–77. http://dx.doi.org/10.1111/j.1479-828x.1992.tb01965.x.

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10

Rosenzweig, Erika B., Darryl Abrams, Mauer Biscotti, Diane Kerstein, Daphnie Drassinower, Daniel Brodie, and Matthew Bacchetta. "Eisenmenger Syndrome and Pregnancy." ASAIO Journal 64, no. 1 (2018): e8-e10. http://dx.doi.org/10.1097/mat.0000000000000548.

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11

Niwa, Koichiro, Joseph K. Perloff, Samuel Kaplan, John S. Child, and Pamela D. Miner. "Eisenmenger syndrome in adults." Journal of the American College of Cardiology 34, no. 1 (July 1999): 223–32. http://dx.doi.org/10.1016/s0735-1097(99)00153-9.

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12

Médaoud, S., D. Hakem, A. Agraniou, N. Ouadahi, S. Ayat, M. Touati, M. Ibrir, S. Lassouaoui, B. Mansouri, and A. Berrah. "PAH revealing Eisenmenger syndrome." European Journal of Internal Medicine 24 (October 2013): e6-e7. http://dx.doi.org/10.1016/j.ejim.2013.08.014.

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13

Meng, Marie-Louise, Annie Fu, Carolyn Westhoff, Matthew Bacchetta, Erika B. Rosenzweig, Ruth Landau, and Richard Smiley. "Eisenmenger Syndrome in Pregnancy." A & A Practice 11, no. 10 (November 2018): 270–72. http://dx.doi.org/10.1213/xaa.0000000000000806.

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14

Grech, Leanne, Adrian Mifsud, Maryanne Caruana, and Francis Carbonaro. "A Case of Advanced Glaucoma with Increased Episcleral Venous Pressure in a 17-Year-Old with Eisenmenger Syndrome." Case Reports in Ophthalmological Medicine 2017 (2017): 1–3. http://dx.doi.org/10.1155/2017/5808047.

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Eisenmenger syndrome refers to reversal of shunt and central cyanosis due to pulmonary hypertension induced by congenital heart disease with a large systemic-to-pulmonary shunt. We report a case of a 17-year-old man with Eisenmenger syndrome who presented with gradual deterioration in visual acuity and was diagnosed with advanced secondary open angle glaucoma. There have been reports of patients suffering from thrombosis due to hyperviscosity associated with this syndrome; however, to our knowledge, the association of secondary open angle glaucoma with Eisenmenger syndrome has not yet been documented.
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15

Korurek, Mehmet, Mustafa Yildiz, Ayhan Yüksel, and Alparslan Şahin. "Simulation of Eisenmenger syndrome with ventricular septal defect using equivalent electronic system." Cardiology in the Young 22, no. 3 (September 26, 2011): 301–6. http://dx.doi.org/10.1017/s1047951111001478.

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AbstractBackground: In this study, we aim to investigate the simulation of the cardiovascular system using an electronic circuit model under normal and pathological conditions, especially the Eisenmenger syndrome. Methods and Results: The Eisenmenger syndrome includes a congenital communication between the systemic and pulmonary circulation, with resultant pulmonary arterial hypertension and right-to-left reversal of flow through the defect. When pulmonary vascular resistance exceeds systemic vascular resistance, it results in hypoxaemia and cyanosis. The Westkessel model including Resistor-Inductance-Capacitance pi-segments was chosen in order to simulate both systemic and pulmonary circulation. The left and right heart are represented by trapezoidal shape stiffness for better simulation results. The Eisenmenger syndrome is simulated using a resistance (septal resistance) connected between the left ventricle and right ventricle points of the model. Matlab® is used for the model implementation. In this model, although there is a remarkable increase in the pulmonary artery pressure and right ventricle pressure, left ventricle pressure, aortic pressure, aortic flow, and pulmonary compliance decrease in the Eisenmenger syndrome. In addition, left-to-right septal flow reversed in these diseases. Conclusion: Our model is effective and available for simulating normal cardiac conditions and cardiovascular diseases, especially the Eisenmenger syndrome.
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16

Huang, J. B., J. Liang, and L. Y. Zhou. "Eisenmenger Syndrome: Not Always Inoperable." Respiratory Care 57, no. 9 (September 1, 2012): 1488–95. http://dx.doi.org/10.4187/respcare.01418.

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17

Khan, Md Isahaque Ali, Sk Yunus Ali, and Mohammad Saiful Hoque. "Eisenmenger Syndrome - a Case Report." Faridpur Medical College Journal 9, no. 2 (November 12, 2015): 105–7. http://dx.doi.org/10.3329/fmcj.v9i2.25687.

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Eisenmenger syndrome (ES), the most advanced form of pulmonary arterial hypertension associated with congenital heart disease, is a devastating condition that has a considerable impact on patient's life. Patients who develop ES typically exhibit one or more of a range of cardiac defects including ventricular septal defects (VSD), atrial septal defects (ASD) and patent ductus arteriosus (PDA). The nature of the congenital defect underlying ES is important because it has prognostic implications. Early diagnosis & treatment of cardiac defect before development of pulmonary hypertension is the key to definite management, otherwise only supportive management can be offered. Our patient Mr. Abdul Khaleque, 55 years old, businessman, non diabetic, non hypertensive admitted in DAMCH, cardiac unit with the complaints of shortness of breath on exertion since childhood, bluish discoloration of nails and toes for 10 years, headache and vertigo for 2 weeks. Initially it was during severe exertion and relieved by rest. Gradually the severity of breathlessness has increased. Now he has developed NYHA class III. He had history of repeated attacks of cough with expectoration of mucoid sputum with occasional scanty amount of blood which did not foul smell and did not change with posture. We diagnose him as Eisenmenger syndrome secondary to ASD and treat him with only medical measure.Faridpur Med. Coll. J. 2014;9(2): 105-107
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18

Vongpatanasin, Wanpen. "The Eisenmenger Syndrome in Adults." Annals of Internal Medicine 128, no. 9 (May 1, 1998): 745. http://dx.doi.org/10.7326/0003-4819-128-9-199805010-00008.

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19

Kim, Minsu, and Wook-Jin Chung. "Current therapy of Eisenmenger syndrome." Journal of Thoracic Disease 8, no. 11 (November 2016): 3009–11. http://dx.doi.org/10.21037/jtd.2016.11.27.

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20

Neema, PraveenKumar. "Eisenmenger syndrome: An unsolved malady." Annals of Cardiac Anaesthesia 15, no. 4 (2012): 257. http://dx.doi.org/10.4103/0971-9784.101844.

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21

Donohue, CM. "Eisenmenger syndrome: a case study." American Journal of Critical Care 10, no. 2 (March 1, 2001): 117–20. http://dx.doi.org/10.4037/ajcc2001.10.2.117.

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22

Hjortshøj, Cristel S., Annette S. Jensen, and Lars Søndergaard. "Advanced Therapy in Eisenmenger Syndrome." Cardiology in Review 25, no. 3 (2017): 126–32. http://dx.doi.org/10.1097/crd.0000000000000107.

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23

Ammash, Naser M., Heidi M. Connolly, Martin D. Abel, and Carole A. Warnes. "Noncardiac surgery in Eisenmenger syndrome." Journal of the American College of Cardiology 33, no. 1 (January 1999): 222–27. http://dx.doi.org/10.1016/s0735-1097(98)00554-3.

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24

Wijesekera, Vishva A., and Dorothy J. Radford. "Hypertrophic Osteoarthropathy in Eisenmenger Syndrome." Congenital Heart Disease 8, no. 3 (February 7, 2012): E65—E69. http://dx.doi.org/10.1111/j.1747-0803.2011.00624.x.

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25

Daliento, Luciano, Luca Rebellato, Annalisa Angelini, Carla Frescura, Elisa Mazzotti, Maristella Rotundo, and Gaetano Thiene. "Fatal outcome in Eisenmenger syndrome." Cardiovascular Pathology 11, no. 4 (July 2002): 221–28. http://dx.doi.org/10.1016/s1054-8807(02)00105-9.

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26

Saxon, John, Shawn Sanders, John Biglane, Michael McMullan, and William Campbell. "TREATMENT OF PSEUDO-EISENMENGER SYNDROME." Journal of the American College of Cardiology 65, no. 10 (March 2015): A633. http://dx.doi.org/10.1016/s0735-1097(15)60633-7.

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27

Moons, Philip, Mary M. Canobbio, and Werner Budts. "Eisenmenger Syndrome: A Clinical Review." European Journal of Cardiovascular Nursing 8, no. 4 (October 2009): 237–45. http://dx.doi.org/10.1016/j.ejcnurse.2009.05.004.

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28

Nayak, Arun Harishchandra, Shweta Avinash Khade, Snehal Shivaji Shinde, Archana Anilkumar Bhosale, and Smurti Kamble. "Pregnancy with Eisenmenger\'s Syndrome." Journal of South Asian Federation of Obstetrics and Gynaecology 14, no. 6 (January 31, 2023): 753–54. http://dx.doi.org/10.5005/jp-journals-10006-2148.

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29

Sosa, Roberto Andrés. "Eisenmenger Syndrome in a canine patient." Ciencia Veterinaria 16, no. 1 (January 1, 2014): 129–32. http://dx.doi.org/10.19137/cienvet2014-16110.

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30

Soefviana, Stefi, and Ardi Zulfariansyah. "Anesthesic Management in Pregnant Woman with Eisenmenger Syndrome." Jurnal Anestesi Obstetri Indonesia 4, no. 1 (March 23, 2021): 26–34. http://dx.doi.org/10.47507/obstetri.v4i1.51.

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The mortality rate in pregnant woman with cardiovascular disease is high.1 Eisenmenger syndrome is a congenital heart disease with a shunt abnormality between the systemic and pulmonary circulation where pulmonary hypertension occurs with right to left shunt at the level of the atria, ventricles or aortopulmonary arteries.2 Patients with Eisenmenger syndrome have a mortality rate up to 56% .1 A 29 years old woman, Gravida 28-29 weeks with a history of congenital heart disease Atrial Septal Defect (ASD) Secundum 27mm-35mm, moderate tricuspid regurgitation, severe pulmonary hypertension with MPAP 78mmHg, ejection fraction (EF) 88%, by bidirectional shunt with Eisenmenger syndrome. The patient underwent elective cesarean section under general anesthesia using Ketamine, Midazolam and Atracurium. The duration of surgery is about 1 hours with stable hemodynamics, EtCO2 within normal limits and no desaturation with a total bleeding of 350 cc. A baby boy was born with a weight range of 1100gr with an APGAR Score of 6/8. Extubation is done by deep extubation. For postoperative, the patient was transferred to the CICU for 3 days for hemodynamic monitoring and moved to the ward for 1 day of treatment and the patient went home. Pregnancy with Eisenmenger syndrome has a high mortality rate. Multidisciplinary team management is required in both elective surgery and the emergency department. Both general and regional anesthesia have their advantages and disadvantages. The principle of anesthesia management is to maintain the balance of the PVR and SVR so that there is no right to left shunt that causes death. Key words: cesarean section, congenital heart disease, Eisenmenger syndrome
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31

Puspitorini Husodo, Dewi, Scarpia P, Rachma C, and Isngadi Isngadi. "Manajemen Anestesi pada Pasien dengan Sindroma Eisenmenger yang Menjalani Seksio Sesarea." Jurnal Anestesi Obstetri Indonesia 1, no. 1 (April 14, 2020): 23–32. http://dx.doi.org/10.47507/obstetri.v1i1.22.

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Pendahuluan sindroma Eisenmenger adalah penyakit jantung bawaan sianotik, termasuk di dalamnya hipertensi pulmonal dengan bidirectional maupun R-L shunt. Penurunan resistensi pembuluh darah sistemik dalam kehamilan akan meningkatan derajat R-L shunt. Mortilitas maternal pada kehamilan dengan sindroma Eisenmenger dilaporkan sekitar 30–70%. Wanita 35 tahun, gravida 32–33 minggu dengan atrial septal defect (ASD )sekundum 1,5cm, regurgitasi tricuspid berat, regurgitasi pulmonal sedang, pulmonal hipertensi berat, ejection fraction (EF) 34%, gagal jantung stage C fungsional klas III, sindroma Eisenmenmenger, saturasi preinduksi 90% dengan non rebreathing mask (NRM) 10 lpm. Kasus kedua, wanita gravida 32 minggu dengan ASD sekundum, regurgitasi trikuspid berat, regurgitasi pulmonal sedang, EF 13%, gagal jantung stage C fungsional klas IV, sindroma Eisenmenger, saturasi preindukasi 66% dengan non rebreathing mask (NRM) 10 lpm. Keduanya menjalani seksio sesarea dengan anestesi umum. Pada kasus pertama, didapatkan atonia uteri yang menyebabkan perdarahan masif dan penurunan tiba-tiba pada alirah darah balik sistemik yang berujung pada kematian. Pada kasus kedua, pasien tidak dapat beradaptasi dengan aliran darah balik uterus setelah bayi lahir. Hal tersebut menyebabkan penurunan saturasi dan hipotensi yang menurunkan tekanan ventrikel kanan, yang berujung pada kematian. Sebagai simpulan, kehamilan dengan sindroma Eisenmenger memiliki insidensi kematian tinggi. Penanganan intensif multidisiplin diperlukan baik dalam operasi elektif dan gawat darurat. Baik anestesi umum maupun regional memiliki kelebihan dan kekurangan tergantung kondisi pasien saat datang. Anesthesia Management in Eisenmenger Syndrome Patient Underwent Caesarean Section Abstract Eisenmenger syndrome is a cyanotic congenital heart disease that includes pulmonary hypertension with reversed or bidirectional shunt. The decreased of systemic vascular resistance is associated with pregnancy increases the degree of right to left shunting. The maternal mortality rate of pregnancy in the presence of Eisenmenger syndrome is reported 30–70%. Female 35yo, gravida 32-33 weeks with secundum ASD 1,5cm, severe tricupid regurgitation, moderate pulmonal regurgiation, severe pulmonal hypertension, ejection fraction (EF) 34%, heart failure stage C functional class III, Eisenmenger syndrome, preinduction oxygen saturation 90% on non rebreathing mask 10 lpm. Second case, 32 weeks pregnant woman with secundum ASD, severe tricupid regurgitation, moderate pulmonal regurgiation, EF 13%, heart failure stage D functional class IV, Eisenmenger syndrome, saturation preinduction 66% on NRM 10 lpm. Both of them undergoing section caesaria with general anesthesia. In first case, uterine atony that leads to massive bleeding makes sudden decrease in systemic vascular resistence and may result in sudden death. In second case, the patient can not adapt the uterine back flow after delivery that makes the saturation decrease and sudden hypotention which make insufficient right ventricular pressure leading to mortality. As conclusion, pregnancy with Eisenmenger syndrome has high mortality incidence. Multidicipline high care treatment is needed for this case, both in elective and emergency setting. Both general and regional anesthesia have advantage and disadvantage, depends on the patient condition.
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32

Ali Abdat, Amira, and Muhammad Yusuf. "Late Referral of Eisenmenger Syndrome in Pregnancy at Dr. Soetomo Hospital Surabaya." International Islamic Medical Journal 1, no. 2 (September 1, 2020): 43–49. http://dx.doi.org/10.33086/iimj.v1i2.1588.

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Background: Pregnancy with Eisenmenger syndrome is an obstetric problem which numbers keep rising every year. The cases require specific,decisive,and multidisciplinary approach.The unavailability of accurate diagnostic procedures, as well as the national consensus that has not been agreed on, all contributes to the increasing number of late referral that cause morbidity and the high risk of mortality. Purpose: To know number and cause of late referral cases with Eisenmenger syndrome at Dr. Soetomo General Hospital, Surabaya in 2018-2019. Methods: Retrospective study by using medical records data of Dr. Soetomo General Hospital, Surabaya on January 2018- December 2019. Result: There are 18 cases of Eisenmenger syndrome from January 2018 to December 2019. Approximately 3 cases are timely referral while 15 cases are late referral cases. From those 15 late referral cases, about 12 cases (80%) are pregnant. Based on the risk factors, 73% of the patients have a congenital heart disease (Atrial septal defect) and severe pulmonary hypertension. In the postpartum referral cases group, 3 cases were referred because of suspected heart disease postpartum. Nearly all of the late referred cases have a bad prognosis those maternal deaths. There were 7 maternal deaths caused by cardiogenic shock. Regarding the source of referral, the majority of referred pregnant patient comes from out of Surabaya (73%), while for the postpartum patient, 13 % was referred from out of Surabaya. According to the referral types, the majority of the late referral cases are emergency referral (73%), as for the postpartum referral, 20% are emergency referral. Conclusion: The number of late referral in Eisenmenger syndrome in Dr. Soetomo general hospital is still high. Further socialization and trainings regarding the early detection and management of Eisenmenger syndrome is still very much needed.
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33

Said, Sarmad, Mateo Porres-Aguilar, Mateo Porres-Munoz, and Debabrata Mukherjee. "Eisenmenger Syndrome: Recent Advances in Pharmacotherapy." Cardiovascular & Hematological Agents in Medicinal Chemistry 11, no. 4 (April 2014): 289–96. http://dx.doi.org/10.2174/1871525712666140321095519.

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34

Platt, TerranceA. "Eisenmenger Syndrome and Congenital Heart Diseases." PVRI Review 5, no. 1 (2013): 15. http://dx.doi.org/10.4103/0974-6013.118823.

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35

Ish, Pranav, JuvvaKishan Srikanth, Nitesh Gupta, and Shibdas Chakrabarti. "Eisenmenger syndrome with pregnancy – Double trouble." Indian Journal of Medical Specialities 11, no. 1 (2020): 44. http://dx.doi.org/10.4103/injms.injms_138_19.

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36

Mukhopadhyay, Saibal, Manish Sharma, S. Ramakrishnan, Jamal Yusuf, Mohit Dayal Gupta, Naveen Bhamri, Vijay Trehan, and Sanjay Tyagi. "Phosphodiesterase-5 Inhibitor in Eisenmenger Syndrome." Circulation 114, no. 17 (October 24, 2006): 1807–10. http://dx.doi.org/10.1161/circulationaha.105.603001.

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37

Dogan, Ferit, Dilek Sen Dokumaci, Ali Yildirim, Erol Bozdogan, Fatima N. Boyaci, Bulent Koca, and Ekrem Karakas. "Brain diffusion changes in Eisenmenger syndrome." British Journal of Radiology 89, no. 1068 (December 2016): 20151007. http://dx.doi.org/10.1259/bjr.20151007.

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38

Gupta, Anunay, Chetan Patel, Saurabh Kumar Gupta, S. Ramakrishnan, Anita Saxena, and Shyam S. Kothari. "Myocardial perfusion abnormalities in Eisenmenger syndrome." Nuclear Medicine Communications 41, no. 3 (March 2020): 206–11. http://dx.doi.org/10.1097/mnm.0000000000001147.

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39

Burger, Andreas, Fabian Schmid, Andreas Berger, Manfred Cejna, and Karl Lhotta. "Floating kidneys associated with Eisenmenger syndrome." Kidney International 94, no. 5 (November 2018): 1029. http://dx.doi.org/10.1016/j.kint.2018.05.010.

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40

Somerville, Jane. "How to manage the Eisenmenger syndrome." International Journal of Cardiology 63, no. 1 (January 1998): 1–8. http://dx.doi.org/10.1016/s0167-5273(97)00264-7.

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41

Ahmad, Mansoor, and Richard Krasuski. "A CASE OF REVERSIBLE “EISENMENGER SYNDROME”." Journal of the American College of Cardiology 63, no. 12 (April 2014): A663. http://dx.doi.org/10.1016/s0735-1097(14)60663-x.

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42

Wort, Stephen John. "Sildenafil in Eisenmenger syndrome: Safety first." International Journal of Cardiology 120, no. 3 (September 2007): 314–16. http://dx.doi.org/10.1016/j.ijcard.2007.03.136.

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43

Simkova, I., A. Remkova, T. Valkovicova, and M. Kaldararova. "PS270 Platelet Abnormalities in Eisenmenger Syndrome." Global Heart 11, no. 2 (June 2016): e59. http://dx.doi.org/10.1016/j.gheart.2016.03.207.

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44

Mukhopadhyav, Partha, Popli Bhattacharya, and Nilofur Begum. "Successful Pregnancy Outcome with Eisenmenger Syndrome." Journal of Obstetrics and Gynecology of India 62, no. 1 (January 24, 2012): 68–69. http://dx.doi.org/10.1007/s13224-011-0111-y.

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45

Simkova, Iveta, and Monika Kaldararova. "Eisenmenger Syndrome - A Nonfailing Right Ventricl." Chest 140, no. 4 (October 2011): 264A. http://dx.doi.org/10.1378/chest.1119296.

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46

Moustafa, Sherif, David J. Patton, Yvonne Balon, Michael S. Connelly, and Nanette Alvarez. "Patent Ductus Arteriosus with Eisenmenger Syndrome." Heart, Lung and Circulation 22, no. 11 (November 2013): 968–69. http://dx.doi.org/10.1016/j.hlc.2013.03.071.

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47

Shah, Kinnari, Samridhi Gulati, Shannon Skinner, and Carmel Moazez. "PULMONARY ARTERIAL HYPERTENSION WITH EISENMENGER SYNDROME." Chest 158, no. 4 (October 2020): A2089. http://dx.doi.org/10.1016/j.chest.2020.08.1804.

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48

Hjortshøj, Cristel S., Annette S. Jensen, Julie A. E. Christensen, Poul Jennum, and Lars Søndergaard. "Sleep-disordered breathing in Eisenmenger Syndrome." International Journal of Cardiology 214 (July 2016): 23–24. http://dx.doi.org/10.1016/j.ijcard.2016.03.108.

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49

Gratsianskaya, Svetlana E., Zarina S. Valieva, Andrei V. Zorin, and Tamila V. Martynyuk. "Clinical, functional and hemodynamic profile of patients with Eisenmenger syndrome in comparison with the group of idiopathic pulmonary hypertension, features of starting specific therapy choice." Systemic Hypertension 16, no. 3 (September 15, 2019): 29–35. http://dx.doi.org/10.26442/2075082x.2019.3.190446.

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Aim. To conduct a comprehensive analysis of the clinical, functional, hemodynamic profile of patients with pulmonary arterial hypertension associated with congenital heart disease (PAH-CHD) and Eisenmenger syndrome, as compared with the group of idiopathic pulmonary hypertension (IPAH) according to the Russian Registry, and also to study the features of drug therapy. Materials and methods. The study involved 20 patients with PAH-CHD and Eisenmenger syndrome and 20 patients with IPAH over 18 years old. All patients had been entered in the Russian registry (NCT03707561). A comparative analysis of clinical, functional, hemodynamic parameters was held. The diagnosis was established in accordance with the algorithm proposed in the Russian guidelines the diagnosis and treatment of PH (2016). Results. In this study, 20 patients with PAH-CHD (16 women and 4 men) and Eisenmenger syndrome and 20 patients with IPAH (18 women and 2 men) were analyzed. Patients were comparable in age and sex. The time from the onset of symptoms to the final diagnosis in the PAH-CHD group was significantly longer: on average, it took three years to establish the diagnosis, whereas in patients with IPAH, on average, after 10.5 months, the correct diagnosis was made (p=0,0006). In the group of patients with Eisenmenger syndrome, there was a significant decrease in SpO2 both at rest and under exertion and averaged 86.5±9.7% at rest and 70±12.3% after exercise (p=0,0002). Conclusions. Patients with Eisenmenger syndrome compared with the IPAH group are characterized by a longer duration of symptoms until the diagnosis, and lower oxygen saturation. When estimating the parameters of pressure in the pulmonary artery (sPAP, dPAP, mPAP), according to the data of right heart catheterization and echo, significantly higher values of pressure in the pulmonary artery and lower values of SpO2 were detected.
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Roy, Tuhin S. "Successful pregnancy outcome in a case of Eisenmenger syndrome." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 11, no. 11 (October 28, 2022): 3193. http://dx.doi.org/10.18203/2320-1770.ijrcog20222819.

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Abstract:
Eisenmenger syndrome is a very rare heart disease in pregnant women. Eisenmenger syndrome is defined as pulmonary hypertension resulting from an uncorrected left to right shunt of a VSD, ASD or patent ductus arteriosus (PDA), with subsequent shunt reversal and cyanosis. Pulmonary hypertension is the prognosis index. The high mortality risk (25-30%) is associated with pregnancy and the peripartum period due to cardiovascular collapse. Pregnancy should be discouraged and reliable contraception, preferably permanent sterilization, advised because of the extreme risk associated with pregnancy. Depo-Provera or progesterone implants are nonsurgical alternatives. Even first-trimester termination is associated with a maternal mortality rate of 5-10%. However, despite all the risks, a few patients deliver successfully with a good maternal and neonatal outcome. We presented a 27-year-old booked G1P0+0 admitted at 34 weeks gestation with Eisenmenger syndrome. She was treated medically during pregnancy, underwent elective caesarean section at 34 weeks of gestation delivered a baby and was subsequently discharged on the 15th postoperative day without any serious complications.
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