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Journal articles on the topic 'Elastic tissue'

Author: Grafiati

Published: 4 June 2021

Last updated: 30 July 2024

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1

Saitow, Cassandra B., Steven G. Wise, Anthony S. Weiss, John J. Castellot, and David L. Kaplan. "Elastin biology and tissue engineering with adult cells." BioMolecular Concepts 4, no. 2 (2013): 173–85. http://dx.doi.org/10.1515/bmc-2012-0040.

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AbstractThe inability of adult cells to produce well-organized, robust elastic fibers has long been a barrier to the successful engineering of certain tissues. In this review, we focus primarily on elastin with respect to tissue-engineered vascular substitutes. To understand elastin regulation during normal development, we describe the role of various elastic fiber accessory proteins. Biochemical pathways regulating expression of the elastin gene are addressed, with particular focus on tissue-engineering research using adult-derived cells.

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2

White, J. F., J. L. Hughes, J. S. Kumaratilake, et al. "Post-embedding methods for immunolocalization of elastin and related components in tissues." Journal of Histochemistry & Cytochemistry 36, no. 12 (1988): 1543–51. http://dx.doi.org/10.1177/36.12.3142951.

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Elastic tissue is composed of amorphous-appearing elastin and 12-nm diameter microfibrils, one component of which has recently been isolated and characterized as the 31 KD microfibril-associated glycoprotein MAGP. Monospecific antibodies to each of these components have been developed in this laboratory. The parameters that determine optimal localization of colloidal gold probes for post-embedding immunolabeling of elastic tissue components have been systematically studied in a variety of normal and developing tissues in mammals and birds. Protein A-gold probes stabilized with dextran have bee

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3

Green, Ellen M., Jessica C. Mansfield, James S. Bell, and C. Peter Winlove. "The structure and micromechanics of elastic tissue." Interface Focus 4, no. 2 (2014): 20130058. http://dx.doi.org/10.1098/rsfs.2013.0058.

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Elastin is a major component of tissues such as lung and blood vessels, and endows them with the long-range elasticity necessary for their physiological functions. Recent research has revealed the complexity of these elastin structures and drawn attention to the existence of extensive networks of fine elastin fibres in tissues such as articular cartilage and the intervertebral disc. Nonlinear microscopy, allowing the visualization of these structures in living tissues, is informing analysis of their mechanical properties. Elastic fibres are complex in composition and structure containing, in a

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4

Trębacz, Hanna, and Angelika Barzycka. "Mechanical Properties and Functions of Elastin: An Overview." Biomolecules 13, no. 3 (2023): 574. http://dx.doi.org/10.3390/biom13030574.

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Human tissues must be elastic, much like other materials that work under continuous loads without losing functionality. The elasticity of tissues is provided by elastin, a unique protein of the extracellular matrix (ECM) of mammals. Its function is to endow soft tissues with low stiffness, high and fully reversible extensibility, and efficient elastic–energy storage. Depending on the mechanical functions, the amount and distribution of elastin-rich elastic fibers vary between and within tissues and organs. The article presents a concise overview of the mechanical properties of elastin and its

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5

Subramaniam, K., H. Kumar, and M. H. Tawhai. "Evidence for age-dependent air-space enlargement contributing to loss of lung tissue elastic recoil pressure and increased shear modulus in older age." Journal of Applied Physiology 123, no. 1 (2017): 79–87. http://dx.doi.org/10.1152/japplphysiol.00208.2016.

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As a normal part of mature aging, lung tissue undergoes microstructural changes such as alveolar air-space enlargement and redistribution of collagen and elastin away from the alveolar duct. The older lung also experiences an associated decrease in elastic recoil pressure and an increase in specific tissue elastic moduli, but how this relates mechanistically to microstructural remodeling is not well-understood. In this study, we use a structure-based mechanics analysis to elucidate the contributions of age-related air-space enlargement and redistribution of elastin and collagen to loss of lung

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6

Lewis, Kevan G., Lionel Bercovitch, Sara W. Dill, and Leslie Robinson-Bostom. "Acquired disorders of elastic tissue: Part II. decreased elastic tissue." Journal of the American Academy of Dermatology 51, no. 2 (2004): 165–85. http://dx.doi.org/10.1016/j.jaad.2004.03.016.

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7

Atarashi, Masaki, Keiichi Miyamoto, and Takashi Horiuchi. "Development of Elastin Biomaterial for Elastic Tissue Engineering." Journal of Life Support Engineering 17, Supplement (2005): 77. http://dx.doi.org/10.5136/lifesupport.17.supplement_77.

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8

Roark, E. F., D. R. Keene, C. C. Haudenschild, S. Godyna, C. D. Little, and W. S. Argraves. "The association of human fibulin-1 with elastic fibers: an immunohistological, ultrastructural, and RNA study." Journal of Histochemistry & Cytochemistry 43, no. 4 (1995): 401–11. http://dx.doi.org/10.1177/43.4.7534784.

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We examined the pattern of fibulin-1 mRNA and protein expression in human tissues and cell lines. Fibulin-1 transcripts were found in RNA isolated from most tissues and a variety of cultured cells, including fibroblasts, smooth muscle cells, and several epithelial cell lines, but not endothelial cells, lymphomyloid cells, or a number of carcinoma and melanoma lines. Immunohistochemical analysis showed that fibulin-1 is an intercellular component of connective tissues, predominantly associated with matrix fibers in tissues such as the cervix, dermis, intimal and medial layers of blood vessels,

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9

Fanning, J. C., and E. G. Cleary. "Identification of glycoproteins associated with elastin-associated microfibrils." Journal of Histochemistry & Cytochemistry 33, no. 4 (1985): 287–94. http://dx.doi.org/10.1177/33.4.3980982.

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The microfibrils associated with elastic tissue have been shown to be predominantly proteinaceous. On the basis of their affinity for cationic stains, including ruthenium red, they have been assumed to be glycoprotein, but more evidence to support this claim has not been adduced. Despite repeated investigation of glycoprotein materials obtained by extraction of elastic tissues with reagents that appear to remove microfibrils, the chemical composition of elastin-associated microfibrils remains obscure. An electron microscopic study of the microfibrils in two elastin-rich tissues (bovine nuchal

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10

Andrés-Ramos, Irene, Victoria Alegría-Landa, Ignacio Gimeno, et al. "Cutaneous Elastic Tissue Anomalies." American Journal of Dermatopathology 41, no. 2 (2019): 85–117. http://dx.doi.org/10.1097/dad.0000000000001275.

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11

Fanning, J. C., J. F. White, J. Kumaratilake, M. A. Gibson, and E. G. Cleary. "Immunoelectron microscopy in normal and diseased elastic tissues." Proceedings, annual meeting, Electron Microscopy Society of America 45 (August 1987): 620–21. http://dx.doi.org/10.1017/s0424820100127530.

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Elastic tissue is recognised to be composed of a major amorphous component (consisting of the protein elastin) and a lesser microfibrillar component (complex structures containing at least two glycoproteins). The study of the components of elastic fibers in developing tissues has been hampered by the difficulty of establishing that the amorphous component is distinguishable from other amorphous structures. This is particularly a problem when the elastic material is deranged, so that the amorphous component is atypical in appearance. We have developed, in rabbits, and then affinity-purified, po

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12

Mecham, Robert P. "Methods in elastic tissue biology: Elastin isolation and purification." Methods 45, no. 1 (2008): 32–41. http://dx.doi.org/10.1016/j.ymeth.2008.01.007.

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13

Lammers, Steven R., Phil H. Kao, H. Jerry Qi, et al. "Changes in the structure-function relationship of elastin and its impact on the proximal pulmonary arterial mechanics of hypertensive calves." American Journal of Physiology-Heart and Circulatory Physiology 295, no. 4 (2008): H1451—H1459. http://dx.doi.org/10.1152/ajpheart.00127.2008.

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Extracellular matrix remodeling has been proposed as one mechanism by which proximal pulmonary arteries stiffen during pulmonary arterial hypertension (PAH). Although some attention has been paid to the role of collagen and metallomatrix proteins in affecting vascular stiffness, much less work has been performed on changes in elastin structure-function relationships in PAH. Such work is warranted, given the importance of elastin as the structural protein primarily responsible for the passive elastic behavior of these conduit arteries. Here, we study structure-function relationships of fresh ar

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14

Ateş Özdemir, Deniz, and Kader Susesi. "The Potential Use of Elastic Tissue Autofluorescence in Formalin-fixed Paraffin-embedded Skin Biopsies." Acta Medica 53, no. 1 (2022): 37–43. http://dx.doi.org/10.32552/2022.actamedica.655.

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Autofluorescence (AF) or naïve-florescence is the natural emission of light by biomolecules. During florescence microscope examination, we realized that elastic tissue is brighter or more autoflourescent than collagen and other biomolecules/cells in the skin. Consequently, we decided to review elastic tissue-related pathologies under a florescence microscope and to report the possible benefits of this technique from selected cases from the paraffin-block archive, by using the protease digestion immunofluorescence method. Selected and clinic-pathologically confirmed 3 elastofibroma dorsi, 3 pse

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15

Perelmuter, Mikhail. "Stress concentration in bone tissues and screw dental implants." Russian journal of biomechanics. 27, no. 2 (2023): 12–20. http://dx.doi.org/10.15593/rjbiomech/2023.2.02.

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Analysis of stress concentration in bone tissues and screw dental implants was per-formed on a model of screw join of the implant and surrounding bone tissues under the action of normal and tangential loads. The computations were performed by the bounda-ry element method for the plane strain state. It was assumed that those hollows in the spongy bone, which had formed in the bone after the implant insertion, are conformed to the screw thread on the implant. Bone tissues are considered as an isotropic and homo-geneous linear-elastic materials. It has been found that with the increasing in the s

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16

Roten, Sonja Vollenweider, Shailesh Bhat, and Jag Bhawan. "Elastic fibers in scar tissue." Journal of Cutaneous Pathology 23, no. 1 (1996): 37–42. http://dx.doi.org/10.1111/j.1600-0560.1996.tb00775.x.

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17

Adams, Brian B., and Diya F. Mutasim. "Elastic Tissue in Fibroepithelial Polyps." American Journal of Dermatopathology 21, no. 5 (1999): 446. http://dx.doi.org/10.1097/00000372-199910000-00007.

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18

Lewis, Kevan G., Lionel Bercovitch, Sara W. Dill, and Leslie Robinson-Bostom. "Acquired disorders of elastic tissue: part I. increased elastic tissue and solar elastotic syndromes." Journal of the American Academy of Dermatology 51, no. 1 (2004): 1–21. http://dx.doi.org/10.1016/j.jaad.2004.03.013.

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19

Krouskop, Thomas A., Thomas M. Wheeler, Faouzi Kallel, Brian S. Garra, and Timothy Hall. "Elastic Moduli of Breast and Prostate Tissues under Compression." Ultrasonic Imaging 20, no. 4 (1998): 260–74. http://dx.doi.org/10.1177/016173469802000403.

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To evaluate the dynamic range of tissue imaged by elastography, the mechanical behavior of breast and prostate tissue samples subject to compression loading has been investigated. A model for the loading was validated and used to guide the experimental design for data collection. The model allowed the use of small samples that could be considered homogeneous; this assumption was confirmed by histological analysis. The samples were tested at three strain rates to evaluate the viscoelastic nature of the material and determine the validity of modeling the tissue as an elastic material for the str

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20

Touw, Deborah M., M. H. Sherebrin, and Margot R. Roach. "The elastic properties of canine abdominal aorta at its branches." Canadian Journal of Physiology and Pharmacology 63, no. 11 (1985): 1378–83. http://dx.doi.org/10.1139/y85-227.

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The elastic properties of the abdominal aorta at regions of junctions were studied using strips from 17 dogs. Strips of tissue cut longitudinally and circumferentially at the celiac, mesenteric, and renal branches were used to compare the properties of the proximal and distal junctions, as well as the aorta and artery regions adjoining. The tissues were stored for at least 24 h to ensure that no active component of the smooth muscle remained. The elastic properties measured here are due to elastin and collagen, with a small contribution from dead smooth muscle cells. The tissue strips were tes

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21

Lyshchik, A., T. Higashi, R. Asato, et al. "Elastic Moduli of Thyroid Tissues under Compression." Ultrasonic Imaging 27, no. 2 (2005): 101–10. http://dx.doi.org/10.1177/016173460502700204.

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The aim of this study was to evaluate the elastic moduli of thyroid tissues under uniaxial compression and to establish the biomechanical fundamentals for accurate interpretation of thyroid elastograms. A total of 67 thyroid samples (24 samples of normal thyroid tissue, 2 samples of thyroid tissue with chronic thyroiditis, 12 samples of adenomatous goiter lesions and 7 samples of follicular adenoma, 19 samples of papillary adenocarcinoma (PAC) and 3 samples of follicular adenocarcinoma (FAC)) obtained from 36 patients who had received thyroid surgery were subjected to biomechanical testing wit

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22

Lillie, M. A., G. J. David, and J. M. Gosline. "Mechanical Role of Elastin-Associated Microfibrils in Pig Aortic Elastic Tissue." Connective Tissue Research 37, no. 1-2 (1998): 121–41. http://dx.doi.org/10.3109/03008209809028905.

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23

Cyril, Divya, Amelia Giugni, Saie Sunil Bangar, et al. "Elastic Fibers in the Intervertebral Disc: From Form to Function and toward Regeneration." International Journal of Molecular Sciences 23, no. 16 (2022): 8931. http://dx.doi.org/10.3390/ijms23168931.

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Despite extensive efforts over the past 40 years, there is still a significant gap in knowledge of the characteristics of elastic fibers in the intervertebral disc (IVD). More studies are required to clarify the potential contribution of elastic fibers to the IVD (healthy and diseased) function and recommend critical areas for future investigations. On the other hand, current IVD in-vitro models are not true reflections of the complex biological IVD tissue and the role of elastic fibers has often been ignored in developing relevant tissue-engineered scaffolds and realistic computational models

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24

Schwartz, E., and R. Fleischmajer. "Association of elastin with oxytalan fibers of the dermis and with extracellular microfibrils of cultured skin fibroblasts." Journal of Histochemistry & Cytochemistry 34, no. 8 (1986): 1063–68. http://dx.doi.org/10.1177/34.8.3525665.

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The formation of a mature elastic fiber is thought to proceed by the deposition of elastin on pre-existing microfibrils (10-12 nm in diameter). Immunohistochemical evidence has suggested that in developing tissues such as aorta and ligamentum nuchae, small amounts of elastin are associated with microfibrils but are not detected at the light microscopic and ultrastructural levels. Dermal tissue contains a complex elastic fiber system consisting of three types of fibers--oxytalan, elaunin, and elastic--which are believed to differ in their relative contents of microfibrils and elastin. According

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25

Mercer, R. R., and J. D. Crapo. "Structural changes in elastic fibers after pancreatic elastase administration in hamsters." Journal of Applied Physiology 72, no. 4 (1992): 1473–79. http://dx.doi.org/10.1152/jappl.1992.72.4.1473.

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Ultrastructural changes in lung parenchymal elastic fibers were studied morphometrically 1, 4, and 12 wk after a single 12-unit dose of pancreatic elastase and in a saline-instilled control group. The mean linear intercept of the parenchymal air spaces was increased in the 1-, 4-, and 12-wk post-elastase instillation groups compared with age-matched controls. The volume of alveolar connective tissue fibers predominantly composed of elastin (elastic fibers) was decreased by 35% 1 wk after the instillation of elastase but returned to control levels by 4 wk. Although the total volume of elastic f

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26

Morris, S. M., P. J. Stone, and G. L. Snider. "Electron microscopic study of human lung tissue after in vitro exposure to elastase." Journal of Histochemistry & Cytochemistry 41, no. 6 (1993): 851–66. http://dx.doi.org/10.1177/41.6.8315277.

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Much of the experimental evidence supporting the hypothesis that pulmonary emphysema results from an imbalance between elastases and anti-elastases in the lung comes from animal models. The present study was designed to examine the effects on human lung tissue of the two elastases that have been most widely used to produce these animal models. Lung tissue was exposed in vitro to human neutrophil elastase (HNE) or porcine pancreatic elastase (PPE). Although both enzymes solubilized protein at similar rates, PPE solubilized elastin five times faster than did HNE. Ultrastructurally, HNE-exposed t

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Gibson, Mark A., Jaliya S. Kumaratilake та Edward G. Cleary. "Immunohistochemical and Ultrastructural Localization of MP78/70 (βig-h3) in Extracellular Matrix of Developing and Mature Bovine Tissues". Journal of Histochemistry & Cytochemistry 45, № 12 (1997): 1683–96. http://dx.doi.org/10.1177/002215549704501212.

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MP78/70 is a matrix protein, with 78-kD and 70-kD isoforms, which was initially identified in bovine tissue extracts designed to solubilize elastin-associated microfibrils. Peptide analysis has shown that MP78/70 is closely related to the human protein, βig-h3. In the present study an antibody raised to a synthetic βig-h3 peptide was shown specifically to identify MP78/70 in purified form and in bovine tissue extracts. This is consistent with MP78/70 and βig-h3 being the bovine and human forms, respectively, of the same protein. The antibody was further affinity-purified on MP78/70 bound to Se

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28

Nonaka, Risa, Takafumi Iesaki, Aurelien Kerever, and Eri Arikawa-Hirasawa. "Increased Risk of Aortic Dissection with Perlecan Deficiency." International Journal of Molecular Sciences 23, no. 1 (2021): 315. http://dx.doi.org/10.3390/ijms23010315.

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Perlecan (HSPG2), a basement membrane-type heparan sulfate proteoglycan, has been implicated in the development of aortic tissue. However, its role in the development and maintenance of the aortic wall remains unknown. Perlecan-deficient mice (Hspg2−/−-Tg: Perl KO) have been found to show a high frequency (15–35%) of aortic dissection (AD). Herein, an analysis of the aortic wall of Perl KO mice revealed that perlecan deficiency caused thinner and partially torn elastic lamina. Compared to the control aortic tissue, perlecan-deficient aortic tissue showed a significant decrease in desmosine con

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29

Elston, Dirk M., Martha L. McCollough, Karen E. Warschaw, and Wilma F. Bergfeld. "Elastic tissue in scars and alopecia." Journal of Cutaneous Pathology 27, no. 3 (2000): 147–52. http://dx.doi.org/10.1034/j.1600-0560.2000.027003147.x.

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30

Bouissou, Hubert, Marie-Thérèse Pieraggi, Monique Julian, and Thérèsa Savait. "The Elastic Tissue of the Skin." International Journal of Dermatology 27, no. 5 (1988): 327–35. http://dx.doi.org/10.1111/j.1365-4362.1988.tb02363.x.

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31

Feng, Gao, Ivan Djordjevic, Vishal Mogal, Richard O'Rorke, Oleksandr Pokholenko, and Terry W. J. Steele. "Elastic Light Tunable Tissue Adhesive Dendrimers." Macromolecular Bioscience 16, no. 7 (2016): 1072–82. http://dx.doi.org/10.1002/mabi.201600033.

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32

Korte, Gary E. "The Elastic Tissue of Bruch's Membrane." Archives of Ophthalmology 107, no. 11 (1989): 1654. http://dx.doi.org/10.1001/archopht.1989.01070020732037.

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33

Kim, Byung-Soo, and David J. Mooney. "Scaffolds for Engineering Smooth Muscle Under Cyclic Mechanical Strain Conditions." Journal of Biomechanical Engineering 122, no. 3 (2000): 210–15. http://dx.doi.org/10.1115/1.429651.

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Cyclic mechanical strain has been demonstrated to enhance the development and function of engineered smooth muscle (SM) tissues, but appropriate scaffolds for engineering tissues under conditions of cyclic strain are currently lacking. These scaffolds must display elastic behavior, and be capable of inducing an appropriate smooth muscle cell (SMC) phenotype in response to mechanical signals. In this study, we have characterized several scaffold types commonly utilized in tissue engineering applications in order to select scaffolds that exhibit elastic properties under appropriate cyclic strain

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Lin, Ying-Ju, An-Ni Chen, Xi Jiang Yin, Chunxiang Li, and Chih-Chien Lin. "Human Microfibrillar-Associated Protein 4 (MFAP4) Gene Promoter: A TATA-Less Promoter That Is Regulated by Retinol and Coenzyme Q10 in Human Fibroblast Cells." International Journal of Molecular Sciences 21, no. 21 (2020): 8392. http://dx.doi.org/10.3390/ijms21218392.

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Elastic fibers are one of the major structural components of the extracellular matrix (ECM) in human connective tissues. Among these fibers, microfibrillar-associated protein 4 (MFAP4) is one of the most important microfibril-associated glycoproteins. MFAP4 has been found to bind with elastin microfibrils and interact directly with fibrillin-1, and then aid in elastic fiber formation. However, the regulations of the human MFAP4 gene are not so clear. Therefore, in this study, we firstly aimed to analyze and identify the promoter region of the human MFAP4 gene. The results indicate that the hum

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35

Cocciolone, Austin J., Jie Z. Hawes, Marius C. Staiculescu, Elizabeth O. Johnson, Monzur Murshed, and Jessica E. Wagenseil. "Elastin, arterial mechanics, and cardiovascular disease." American Journal of Physiology-Heart and Circulatory Physiology 315, no. 2 (2018): H189—H205. http://dx.doi.org/10.1152/ajpheart.00087.2018.

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Large, elastic arteries are composed of cells and a specialized extracellular matrix that provides reversible elasticity and strength. Elastin is the matrix protein responsible for this reversible elasticity that reduces the workload on the heart and dampens pulsatile flow in distal arteries. Here, we summarize the elastin protein biochemistry, self-association behavior, cross-linking process, and multistep elastic fiber assembly that provide large arteries with their unique mechanical properties. We present measures of passive arterial mechanics that depend on elastic fiber amounts and integr

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Golbad, Sara, and Mohammad Haghpanahi. "Hyperelastic Model Selection of Tissue Mimicking Phantom Undergoing Large Deformation and Finite Element Modeling for Elastic and Hyperelastic Material Properties." Advanced Materials Research 415-417 (December 2011): 2116–20. http://dx.doi.org/10.4028/www.scientific.net/amr.415-417.2116.

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Pathologies in soft tissues are associated with changes in their elastic properties. Tumor tissues are usually stiffer than the fat tissues and other normal tissues and show the nonlinear behavior in large deformations. There have been a lot of researches about elastography (linear and nonlinear) as a new detecting technique based on mechanical behavior of tissue. In order to formulate the tissue’s nonlinear behavior, a strain energy function is required. For better estimation of nonlinear tissue parameters in elasticity imaging, non linear stress-strain curve of phantom is used. This work pre

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GIBBONS, CAROL A., and ROBERT E. SHADWICK. "Circulatory Mechanics in the Toad Bufo Marinus: I. Structure and Mechanical Design of the Aorta." Journal of Experimental Biology 158, no. 1 (1991): 275–89. http://dx.doi.org/10.1242/jeb.158.1.275.

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This study describes several important mechanical design features of the aorta of a typical poikilothermic vertebrate. A strong functional similarity to the aorta of mammals is apparent, but some structural and mechanical differences are seen that reflect the lower pressure and simpler haemodynamics of the poikilothermic circulation. 1. The aorta is highly distensible, resilient and non-linearly elastic, giving it the requisite properties to act as an effective storage element in the arterial circulation. 2. An abrupt transition from high compliance (low elastic modulus) to relatively low comp

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38

Hamandi, Farah, James T. Tsatalis, and Tarun Goswami. "Retrospective Evaluation and Framework Development of Bone Anisotropic Material Behavior Compared with Elastic, Elastic-Plastic, and Hyper-Elastic Properties." Bioengineering 9, no. 1 (2021): 9. http://dx.doi.org/10.3390/bioengineering9010009.

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The main motivation for studying damage in bone tissue is to better understand how damage develops in the bone tissue and how it progresses. Such knowledge may help in the surgical aspects of joint replacement, fracture fixation or establishing the fracture tolerance of bones to prevent injury. Currently, there are no standards that create a realistic bone model with anisotropic material properties, although several protocols have been suggested. This study seeks to retrospectively evaluate the damage of bone tissue with respect to patient demography including age, gender, race, body mass inde

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39

Sambani, Kyriaki, Stylianos Vasileios Kontomaris, and Dido Yova. "Atomic Force Microscopy Imaging of Elastin Nanofibers Self-Assembly." Materials 16, no. 12 (2023): 4313. http://dx.doi.org/10.3390/ma16124313.

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Elastin is an extracellular matrix protein, providing elasticity to the organs, such as skin, blood vessels, lungs and elastic ligaments, presenting self-assembling ability to form elastic fibers. The elastin protein, as a component of elastin fibers, is one of the major proteins found in connective tissue and is responsible for the elasticity of tissues. It provides resilience to the human body, assembled as a continuous mesh of fibers that require to be deformed repetitively and reversibly. Thus, it is of great importance to investigate the development of the nanostructural surface of elasti

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40

Minin, Yuriy V., Pavlo A. Virych, Anton F. Karas, et al. "Regeneration of artificial injuries external ear elastic cartilage of rabbits after stem cells local injection." OTORHINOLARYNGOLOGY, No3-4(5) 2022 (July 29, 2022): 36–43. http://dx.doi.org/10.37219/2528-8253-2022-3-36.

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Introduction: Every year, a large number of patients from developed countries turn to surgical departments with the reconstruction problems of the auricle cartilage. A some of surgical procedures was developed to correct minor defects due to the low regenerative capacity of elastic cartilage. Stem cells can potentially differentiate into chondroblasts and chondrocytes and restore cartilage integrity. Many factors influence on the differentiation and proliferation of stem cells, which complicates the method application. Therefore, the investigation of using stem cells to regeneration elastic ca

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Pugno, Nicola Maria, and Qiang Chen. "Modeling the Elastic Anisotropy of Woven Hierarchical Tissues: Experimental Comparison on Biological Materials and Design of a New Class of Scaffolds." Advances in Science and Technology 76 (October 2010): 153–58. http://dx.doi.org/10.4028/www.scientific.net/ast.76.153.

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This paper models the elastic properties of 2-D woven hierarchical tissues, assuming an orthotropic material of warp and fill yarns at level 0. Considering matrix transformation and stiffness averaging, stiffness matrices of warp and fill yarns of the tissue at level i are employed to calculate those of the tissue at level i+1. We compare our theory with another approach from the literature on tendons and experiments on leaves performed by ourselves. The result shows the possibility of designing a new class of hierarchical 2-D scaffolds with desired elastic anisotropy, better matching the anis

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Zamir, Evan A., and Larry A. Taber. "On the Effects of Residual Stress in Microindentation Tests of Soft Tissue Structures." Journal of Biomechanical Engineering 126, no. 2 (2004): 276–83. http://dx.doi.org/10.1115/1.1695573.

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Microindentation methods are commonly used to determine material properties of soft tissues at the cell or even sub-cellular level. In determining properties from force-displacement (FD) data, it is often assumed that the tissue is initially a stress-free, homogeneous, linear elastic half-space. Residual stress, however, can strongly influence such results. In this paper, we present a new microindentation method for determining both elastic properties and residual stress in soft tissues that, to a first approximation, can be regarded as a pre-stressed layer embedded in or adhered to an underly

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Kielty, Cay M., Simon Stephan, Michael J. Sherratt, Matthew Williamson, and C. Adrian Shuttleworth. "Applying elastic fibre biology in vascular tissue engineering." Philosophical Transactions of the Royal Society B: Biological Sciences 362, no. 1484 (2007): 1293–312. http://dx.doi.org/10.1098/rstb.2007.2134.

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For the treatment of vascular disease, the major cause of death in Western society, there is an urgent need for tissue-engineered, biocompatible, small calibre artery substitutes that restore biological function. Vascular tissue engineering of such grafts involves the development of compliant synthetic or biomaterial scaffolds that incorporate vascular cells and extracellular matrix. Elastic fibres are major structural elements of arterial walls that can enhance vascular graft design and patency. In blood vessels, they endow vessels with the critical property of elastic recoil. They also influ

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Rosenquist, T. H., and J. R. McCoy. "A new interpretation of the direct Schiff reaction of elastic connective tissue." Journal of Histochemistry & Cytochemistry 35, no. 11 (1987): 1205–15. http://dx.doi.org/10.1177/35.11.2443556.

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A direct Schiff reaction of elastic tissues has been known for many years, but the nature of the native aldehyde-rich components has not been clear. In this study, chicken, quail, and rat embryos and adult rat lung, aorta, and kidney were fixed in methacarn or in a formalin solution, embedded in paraffin, and sections of 8-10 micron obtained. Rehydrated sections were incubated for various periods in solutions of the enzymes chondroitinase ABC, clostripain, collagenase, elastase, heparatinase, hyaluronidase, subtilisin Carlsberg ("protease"), or trypsin, and in solutions of phosphomolybdic acid

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XIONG, Jiang, Wei GUO, Ren WEI, Shang-wei ZUO, Xiao-ping LIU, and Tao ZHANG. "Elastic fiber regeneration in vitro and in vivo for treatment of experimental abdominal aortic aneurysm." Chinese Medical Journal 126, no. 3 (2013): 437–41. http://dx.doi.org/10.3760/cma.j.issn.0366-6999.20122151.

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Background The pathological characteristics of abdominal aortic aneurysm (AAA) involved the regression of extracellular matrix (ECM) in aortic walls, especially elastic structure in medial layer. As the major structural protein of aorta, elastin contributes to the extensibility and elastic recoil of the vessels. We hypothesized that overexpression of elastin in vessel walls might regenerate the elastic structure of ECM, restore the elastic structure of the aneurysmal wall, and eventually lead to a reduction of aortic diameters (ADs) in an experimental model of AAA. Methods Tropoelastin (TE) of

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Hassler, Ove, and Sören Herbertsson. "ELASTASE TREATMENT OF FIXED ARTERIAL ELASTIC TISSUE." Acta Pathologica Microbiologica Scandinavica 55, no. 1 (2009): 14–18. http://dx.doi.org/10.1111/j.1699-0463.1962.tb04092.x.

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Aessopos, A., D. Farmakis, and D. Loukopoulos. "Elastic tissue abnormalities in inherited haemolytic syndromes." European Journal of Clinical Investigation 32, no. 9 (2002): 640–42. http://dx.doi.org/10.1046/j.1365-2362.2002.01033.x.

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URRY, DAN W., and ASIMA PATTANAIK. "Elastic Protein-based Materials in Tissue Reconstructiona." Annals of the New York Academy of Sciences 831, no. 1 (2006): 32–46. http://dx.doi.org/10.1111/j.1749-6632.1997.tb52182.x.

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Long, Jennifer L., and Robert T. Tranquillo. "Elastic fiber production in cardiovascular tissue-equivalents." Matrix Biology 22, no. 4 (2003): 339–50. http://dx.doi.org/10.1016/s0945-053x(03)00052-0.

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Damiano, V. V. "Neutrophil elastase and elastic tissue in emphysema." Journal of Clinical Pathology 42, no. 1 (1989): 114–15. http://dx.doi.org/10.1136/jcp.42.1.114.

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