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Dissertations / Theses on the topic 'Elastomeric substrates'

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1

Jawad, Hedeer Zuhair. "Development and characterisation of elastomeric block copolymeric substrates for myocardial tissue engineering using embryonic stem cell derived cardiomyocytes." Thesis, Imperial College London, 2009. http://hdl.handle.net/10044/1/5473.

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Cardiac patches comprised of embryonic stem cell derived cardiomyocytes (ESC-CMs) attached to biodegradable polymeric substrates were developed for patients suffering from heart attacks. Cardiomyocytes were derived from mouse and human embryonic stem cell (ESC). Thermoplastic elastomeric (TPE) block co-polymers poly(ethylene terephthalate)/dilionic acid (PET/DLA), a relatively slow degrading biomaterial, served as substrates to deliver cardiomyocytes and to further support the myocardium after an infarct. Additionally, titanium dioxide (TiO2) nanoparticles (NPs) (mean size 23 nm), were incorpo
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2

Hayirlioglu, Arzu. "Directed Assembly of Block Copolymer Films Via Surface Energy Tunable Elastomers." University of Akron / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=akron1399049231.

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3

Mohan, Greeshma. "Silicone Elastomer-Based Combinatorial Biomaterial Gradients for High Throughput Screening of Cell-Substrate Interactions." Scholar Commons, 2015. http://scholarcommons.usf.edu/etd/5857.

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Biomaterials have evolved over the years from the passive role of mere biocompatibility to an increasingly active role of presenting instructive cues to elicit precise responses at the molecular and cellular levels. Various characteristics common to synthetic biomaterials in vitro and extracellular matrices in vivo, such as immobilized functional or peptide groups, mechanical stiffness, bulk physical properties and topographical features, are key players that regulate cell response. The dynamics in the cell microenvironment and at the cell adhesive interface trigger a web of cell-material and
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4

Cansell, Elsa. "Adhérisation des élastomères sur des substrats métalliques : étude des mécanismes d'adhésion." Thesis, Paris Est, 2019. http://www.theses.fr/2019PESC0049.

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Les assemblages élastomère/métal peuvent être réalisés avec plusieurs procédés d’adhérisation. Ces travaux de thèse se focalisent sur l’étude du procédé d’adhérisation chimique qui utilise des adhésifs liquides et réactifs à chaud afin de créer l’assemblage grâce à une élévation de température et de pression. Ces adhésifs sont communément appelés agents d’adhérisation. La formulation de ces adhésifs est complexe et mal connue. L’objectif de ces travaux de thèse est les mécanismes d’adhésion ayant lieu au cours du procédé d’adhérisation chimique et d’expliquer le rôle des agents d’adhérisation.
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5

Querceto, Silvia. "Biomimetic materials for novel cardiac regeneration approaches." Doctoral thesis, Università di Siena, 2022. http://hdl.handle.net/11365/1211514.

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The quest for novel biomaterials to promote cell structural and functional maturation for cardiac tissue regeneration has emphasized a need to create microenvironments with physiological features. Substrate stiffness constitutes a structural property of crucial importance in the field of tissue engineering and many studies have shown how cardiac cells sense the rigidity of the substrate on which they grow. In this work, we focused on the relevance of substrates mimicking cardiac extracellular matrix (cECM) rigidity for the understanding of the complex interplay between the extracellular and in
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6

Psarra, Erato. "Study on magneto-sensitive solids : Experiments, Theory and Numerics." Thesis, Université Paris-Saclay (ComUE), 2018. http://www.theses.fr/2018SACLX094/document.

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Cette étude traite de la stabilité et la post-bifurcation des élastomères magnétorhéologiques isotropes (MRE). Les MRE sont des élastomères comprenant une fraction en volume fini de particules de fer magnétisables, réparties de façon aléatoire dans le volume. Plus précisément, un système de film/substrat magnéto-élastique non linéaire est exploité expérimentalement, numériquement et théoriquement pour obtenir un contrôle actif de la rugosité de la surface du film. L'interaction non-intuitive entre le champ magnétique et la déformation élastique est due au choix des matériaux et de la géométrie
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7

Flaig, Florence. "Elaboration of nanofibrous biomimetic scaffolds based on poly(glycerol sebacate) for cardiac tissue engineering." Thesis, Strasbourg, 2019. http://www.theses.fr/2019STRAE045.

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L’ingénierie tissulaire cardiaque permet de promouvoir la régénération du cœur. Cette technique repose sur l’utilisation d’un substrat où se développent les cellules. Pour être performant, ce substrat doit mimer les propriétés mécaniques et structurelles du myocarde. Pour cette thèse, le poly(sébaçate de glycérol) (PGS), un élastomère biocompatible, a été choisi comme matériau de base. Sa synthèse a été étudiée, montrant quels sont les paramètres à contrôler pour obtenir les propriétés attendues. En particulier, des propriétés mécaniques adaptées au muscle cardiaque peuvent être obtenues. La m
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8

Picard, Loïc. "Mise au point d'additifs siliciés pour l'adhérisation d'élastomères silicone sur supports métalliques." Thesis, Lyon, INSA, 2014. http://www.theses.fr/2014ISAL0114.

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L’objectif de ces travaux de thèse était de développer un primaire d’adhésion stable, permettant l’adhérisation de tous types d’élastomères silicone sur une grande majorité de surfaces métalliques, et ce de façon reproductible. Dans un premier temps, une étude bibliographique détaillée des différentes formulations de primaire à base de silanes utilisées pour l’adhésion de tous types d’élastomères silicone (EVC, EVF et LSR) a été effectuée. Pour compléter la compréhension du système métal/primaire d’adhésion/élastomère silicone étudié, trois formulations de primaire, dont une formulation « mais
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9

Martinot, Emmanuelle. "Indentation de films élastiques complexes par des sondes souples." Phd thesis, Université Paris Sud - Paris XI, 2012. http://tel.archives-ouvertes.fr/tel-00786422.

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La compréhension des mécanismes qui pilotent la transmission des contraintes aux interfaces déformables est au centre de nombreuses problématiques touchant des applications actuelles utilisant un film mince de polymère souple comme couche interfaciale. Arriver à caractériser de tels films fins est encore un défi aujourd'hui car l'analyse des mesures expérimentales destinées à extraire les contributions dues aux films est complexe et délicate et les techniques usuelles de caractérisation sont peu adaptées aux systèmes. Ce travail étudie la réponse mécanique de deux types de systèmes modèles au
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10

"The Evaluation of the Numerical Methods to Study the Buckling of Stiff Films on Elastomeric Substrates." Master's thesis, 2010. http://hdl.handle.net/2286/R.I.8820.

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abstract: Ordered buckling of stiff films on elastomeric substrates has many applications in the field of stretchable electronics. Mechanics plays a very important role in such systems. A full three dimensional finite element analysis studying the pattern of wrinkles formed on a stiff film bonded to a compliant substrate under the action of a compressive force has been widely studied. For thin films, this wrinkling pattern is usually sinusoidal, and for wide films the pattern depends on loading conditions. The present study establishes a relationship between the effect of the load applied at a
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11

Lakshminarayanan, Oppili Prasad. "Conformal Electronics on Elastomers: Packaging Methods and Design Rules." Thesis, 2019. https://etd.iisc.ac.in/handle/2005/4383.

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Flexible Electronics is a multi-disciplinary domain that creates intersections among elec- tronics, materials-science, mechanics, packaging, sensor-design, etc., to build exible / stretchable / conformal electronic circuits and systems. The spectrum of this field is very broad, and hence the approaches, materials/substrates di er significantly based on applications and requirements. In the recent years, development of electronic circuits and systems on wearable elastomeric substrates has gained a lot of research attentions due to its possible applications in wearable bio-medical device
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12

Chen, Chao-Ming, and 陳昭明. "Design and Analysis of Stretchable Electrical Routings on Elastomeric Substrate." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/55191222671607217586.

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博士<br>國立清華大學<br>動力機械工程學系<br>103<br>Stretchable electrical devices, superior to flexible electrical devices, possess large capacity of mechanical deformability, thereby are more advantageous for biomedical and textile applications. To enhance the stretchability performance, the interconnecting wires go with serpentine geometry either in horizontal or vertical direction. The objective of the present study is to find the design rule of the stretchable electrical routing on elastomeric substrate. The simulation analysis is in agreement with the experimental studies in references, the proposed two-
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Lin, Tzu-Yu, and 林子渝. "Investigation of tunable optical properties of gallium nanoparticles on elastomer substrates." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/49270321950441200934.

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碩士<br>國立中央大學<br>材料科學與工程研究所<br>105<br>In recent years, great interest has arisen in flexible substrate and plasmonic. Additionally, gallium has emerged as a promising new material for plasmonics among a growing family of novel materials. This dissertation aims to explore that choose a suitable polymer elastomer substrate and gallium nanoparticles transfer to elastomer substrate by soft lithography, because the elastomer (PDMS) has unique tenability, control spacing between nanoparticles via alter the elastomer strain ratio. We use UV-Visible spectrometer to analyze optical properties. Finally,
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14

Yan, Jia-Nan, and 顏嘉男. "Sensitivity-Enhanced SERS Substrate Fabrication by Nanoimprinting Compressed PDMS Elastomer." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/56rd3h.

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碩士<br>國立虎尾科技大學<br>光電與材料科技研究所<br>101<br>This paper mainly explores the components for enhancing the Raman scattering effect. It attempts to reprint grating through Soft Lithography matching with the UV-based Nanoimprint Lithography (UV-NIL) technology, indirectly changing the grating period via the extruding die core to reprint the grating structure on a glass substrate, and finally make a layer of Au plated on the grating structure by thermal evaporation to finish the surface-enhancing Raman spectrum component. In order to learn the component shape, period and modulation depth, we use an Atomi
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15

Grandinetti, Bruno. "Development of light-responsive materials for biomedical applications - A perspective on the use of Liquid Crystalline Elastomers as artificial muscles and cell culture substrates." Doctoral thesis, 2022. http://hdl.handle.net/2158/1265117.

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Smart soft materials possess an unmatched potential in biomedical applications. Among them, liquid crystalline elastomers (LCEs) exhibit various properties exploited in the fabrication of microrobots and responsive coatings, and, very recently, also in the design of biomedical implants and devices. LCEs are shape-changing materials able to modify their structure upon stimulation, generating tension during this process. Biocompatibility and cell-instructiveness have been demonstrated for different classes of LCEs, whose mechanical properties and response time can be easily tuned. The research p
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