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Dissertations / Theses on the topic 'Electrophysiological activity'

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1

Hsieh, Ying-Hsin. "Electrophysiological Characterization of SecA-dependent Protein-conducting Channel." Digital Archive @ GSU, 2011. http://digitalarchive.gsu.edu/biology_diss/107.

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Sec translocon is the major machinery for protein translocation in E.coli including SecYEG, SecA and other Sec proteins. It is generally assumed that during translocation process, SecYEG serves as a protein-conducting channel and transports the protein across membranes by using SecA ATPase as driving force. However, previous work suggested that protein translocation can occur without SecYEG. In order to understand the role of SecA in this SecYEG-independent process, we use voltage clamp recording as a tool to study the ionic activity of SecA-dependent protein-conducting channel. In a major de
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2

Dixon, Thomas Oliver. "An electrophysiological examination of visuomotor activity elicited by visual object affordances." Thesis, University of Plymouth, 2016. http://hdl.handle.net/10026.1/6758.

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A wide literature of predominantly behavioural experiments that use Stimulus Response Compatibility (SRC) have suggested that visual action information such as object affordance yields rapid and concurrent activation of visual and motor brain areas, but has rarely provided direct evidence for this proposition. This thesis examines some of the key claims from the affordance literature by applying electrophysiological measures to well established SRC procedures to determine the verities of the behavioural claims of rapid and automatic visuomotor activation evoked by viewing affording objects. Th
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3

Enns-Ruttan, Jennifer Sylvia. "Analysis of electrophysiological models of spontaneous secondary spiking and triggered activity." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape15/PQDD_0005/NQ34522.pdf.

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4

Bamidis, Panagiotis D. "Spatio-temporal evolution of interictal epileptic activity : a study with unaveraged multichannel MEG data in association with MRIs." Thesis, Open University, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.318685.

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5

Zhang, Heye. "An inverse framework for estimating cardiac electrophysiological activity from medical image sequence /." View abstract or full-text, 2007. http://library.ust.hk/cgi/db/thesis.pl?ECED%202007%20ZHANGHY.

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6

Batashvili, Michael. "The electrophysiological correlates of maths anxiety : exploring the role of gamma activity." Thesis, University of Derby, 2016. http://hdl.handle.net/10545/618739.

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This thesis set out to investigate the electrophysiological correlates of maths anxiety (MA). Research has shown that those with high MA (HMA) tend to have poorer accuracy and increased reaction time on maths based tasks and that high maths anxious individuals avoid situations where they might have to use maths. This can impact on their future by restricting their degree or job prospects. Previous research has identified the behavioural cognitive and psychological effects of MA and recently studies have begun to examine the associated underlying mechanisms in the brain. Chapter one outlines th
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7

Mortensen, Martin. "GABAa receptor pharmacology : electrophysiological studies of agonist activity on reconstituted human GABAa receptors /." [Cph.] : Department of Pharmacology, The Royal Danish School of Pharmacy, 2002. http://www.dfh.dk/phd/defences/martinmortensen.htm.

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8

Azami, Hamed. "Entropy-based nonlinear analysis for electrophysiological recordings of brain activity in Alzheimer's disease." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/31106.

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Alzheimer’s disease (AD) is a neurodegenerative disorder in which the death of brain cells causes memory loss and cognitive decline. As AD progresses, changes in the electrophysiological brain activity take place. Such changes can be recorded by the electroencephalography (EEG) and magnetoencephalography (MEG) techniques. These are the only two neurophysiologic approaches able to directly measure the activity of the brain cortex. Since EEGs and MEGs are considered as the outputs of a nonlinear system (i.e., brain), there has been an interest in nonlinear methods for the analysis of EEGs and ME
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9

Munk, Andrew A. "Electrophysiological and molecular characterization of ionic channels underlying excitability in cardiac tissues displaying pacemaking activity." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape11/PQDD_0018/NQ44527.pdf.

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10

Slewa, Barbara Lidia [Verfasser]. "Electrophysiological activity of basal ganglia under deep brain stimulation in the rat model / Barbara Lidia Slewa." Tübingen : Universitätsbibliothek Tübingen, 2020. http://d-nb.info/1223451445/34.

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11

Travis, Kathleen Ann. "An electrophysiological analysis of neuronal spontaneous activity, temperature sensitivity and osmosensitivity in normotensive and hypertensive rats /." The Ohio State University, 1988. http://rave.ohiolink.edu/etdc/view?acc_num=osu148759830383751.

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12

Phoka, Elena. "Sensory induced long-lasting modification of spontaneous activity in the somatosensory cortex : electrophysiological and modelling studies." Thesis, Imperial College London, 2012. http://hdl.handle.net/10044/1/9602.

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Emerging evidence suggests that spontaneous neocortical activity is not merely noise but can be modulated and/or engaged by sensory stimulation. We examined whether naturalistic sensory stimulation can induce specific long-term changes in spontaneous cortical state dynamics in the mouse somatosensory cortex, using both in vivo electrophysiology and modelling. Repetitive, high-frequency multi-whisker stimulation using sandpaper resulted in spontaneous ring rate increase of layer IV and Vb multi-units. The ring rate increase in these layers was sustained for at least 25 minutes following the sti
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13

McBain, Christopher J. "An electrophysiological investigation of the spontaneously arising epileptiform activity seen in organotypic cultures of neonate rat hippocampus." Thesis, University of Cambridge, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.293815.

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14

Arend, Anna Marie [Verfasser], and Hubert D. [Akademischer Betreuer] Zimmer. "Investigating visual working memory : electrophysiological delay activity and plasticity of selection mechanisms / Anna Marie Arend. Betreuer: Hubert D. Zimmer." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2013. http://d-nb.info/1052781160/34.

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15

Hsu, Chia-Fen. "The electrophysiological correlates of spontaneous brain activity during resting, waiting, and prospective cognition : exploring putative neural markers for ADHD." Thesis, University of Southampton, 2015. https://eprints.soton.ac.uk/374937/.

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16

Martínez, Mateu Laura. "Mapping of the electrical activity of human atria. Multiscale modelling and simulations." Doctoral thesis, Universitat Politècnica de València, 2018. http://hdl.handle.net/10251/104604.

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La fibrilación auricular es una de las arritmias cardíacas más comunes observadas en la práctica clínica. Por lo tanto, es de vital importancia desarrollar nuevas tecnologías destinadas a diagnosticar y acabar con este tipo de arritmia, para mejorar la calidad de vida de los pacientes y reducir los costes de los sistemas nacionales de salud. En los últimos años ha aumentado el uso de las nuevas técnicas de mapeo auricular, basadas en sistemas multi-electrodo para mapear la actividad eléctrica en humanos. Dichas técnicas permiten localizar y ablacionar los impulsores de la fibrilación auricular
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17

Whalley, Benjamin Jason. "Electrophysiological investigation of some mechanisms underlying muscarinic agonist-induced epileptiform activity observed in immature rat olfactory cortical brain slices in vitro." Thesis, University College London (University of London), 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.406294.

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18

Boina, Dhana Raj. "Evaluation of Anion Transporters as Potential Target Sites for Insect and Nematode Control: Toxicological, Electrophysiological, and Molecular Studies." Diss., Virginia Tech, 2008. http://hdl.handle.net/10919/25975.

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In this study, four anion transporter (AT) blockers, DIDS (4, 4â -diisothiocyanatostilbene-2, 2â -disulfonic acid), 9-AC (anthracene-9-carboxylic acid), NPPB (5-nitro-2-(3-phenylpropylamino) benzoic acid), and IAA-94 (indanyloxy acetic acid) were selected to evaluate ATs as potential target sites for insect and nematode control. All the AT blockers showed slowly developing toxicity against second-stage larvae of <i>Meloidogyne incognita</i> (Kofoid and White 1919) Chitwood 1949 and adults of <i>Caenorhabditis elegans</i> Maupas 1900 but not against third-stage larvae of <i>Heterorhabditi
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19

Kreuzer, Matthias Verfasser], Eberhard [Akademischer Betreuer] [Kochs, and Michael [Akademischer Betreuer] Schemann. "Analysis of anesthetic-induced effects on extracellular electrophysiological activity in cortical and subcortical neuronal networks / Matthias Kreuzer. Gutachter: Eberhard Kochs ; Michael Schemann. Betreuer: Eberhard Kochs." München : Universitätsbibliothek der TU München, 2014. http://d-nb.info/1060482673/34.

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20

López, Pérez Alejandro Daniel. "Computational modelling of the human heart and multiscale simulation of its electrophysiological activity aimed at the treatment of cardiac arrhythmias related to ischaemia and Infarction." Doctoral thesis, Universitat Politècnica de València, 2019. http://hdl.handle.net/10251/124973.

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[ES] Las enfermedades cardiovasculares constituyen la principal causa de morbilidad y mortalidad a nivel mundial, causando en torno a 18 millones de muertes cada año. De entre ellas, la más común es la enfermedad isquémica cardíaca, habitualmente denominada como infarto de miocardio (IM). Tras superar un IM, un considerable número de pacientes desarrollan taquicardias ventriculares (TV) potencialmente mortales durante la fase crónica del IM, es decir, semanas, meses o incluso años después la fase aguda inicial. Este tipo concreto de TV normalmente se origina por una reentrada a través de canal
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21

Arib, Ouafa. "Étude électrophysiologique des effets du tabac, de sa fumée et de la nicotine sur des neurones dopaminergiques de l’aire tegmentale ventrale in vivo chez le rat, la souris sauvage et la souris β2 KO". Thesis, Paris Est, 2009. http://www.theses.fr/2009PEST0039/document.

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La nicotine est considérée comme étant la « molécule » addictogène de la cigarette et du tabac. Mais différentes études cliniques, utilisant notamment des substituts nicotiniques, débouchent pratiquement toutes sur une même conclusion : efficacité ne dépassant que de peu celle d’un placebo, et très limitée dans le temps, contrastant avec le pouvoir hautement addictif du tabac, qu'il soit chiqué, prisé ou fumé. Dans ce travail de thèse, nous avons essayé de mettre en évidence le rôle que pourraient avoir certains des autres composés présents dans le tabac ou produits par pyrolyse. Nous avons d’
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22

Cano, García Jordi. "Prediction of the effects of drugs on cardiac activity using computer simulations." Doctoral thesis, Universitat Politècnica de València, 2021. http://hdl.handle.net/10251/164094.

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[ES] Las enfermedades cardiovasculares siguen siendo la principal causa de muerte en Europa. Las arritmias cardíacas son una causa importante de muerte súbita, pero sus mecanismos son complejos. Esto denota la importancia de su estudio y prevención. La investigación sobre electrofisiología cardíaca ha demostrado que las anomalías eléctricas causadas por mutaciones que afectan a canales cardíacos pueden desencadenar arritmias. Sorprendentemente, se ha descubierto una gran variedad de fármacos proarrítmicos, incluidos aquellos que usamos para prevenirlas. Las indicaciones de uso de fármacos actu
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23

Wegrzyk, Jennifer. "Wide-pulse, high-frequency electrical stimulation" in humans : Combined investigations of neural and muscular function using electrophysiological and nuclear magnetic resonance techniques." Thesis, Aix-Marseille, 2014. http://www.theses.fr/2014AIXM4080.

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L'ectrostimulation dite conventionnelle (CONV) est délivrée par des impulsions électriques de basse fréquence (≤ 50 Hz), de courte durée (&lt; 400 μs) et de haute intensité. Ce type d'ESNM permet ainsi d'évoquer une contraction musculaire grâce à l'activation directe des axones moteurs et est associé à une fatigue musculaire exagérée par rapport aux contractions volontaires (VOL). Au contraire, lors de l'utilisation d'impulsions de longues durées (1 ms), de hautes fréquences (≥ 80 Hz) et de faibles intensités (i.e. protocole « Wide-Pulse, High-Frequency » (WPHF)), une partie de la force muscul
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24

Lajante, Mathieu. "Contribution des neurosciences à l’étude de l’émotion en persuasion publicitaire : concepts, méthodes et mesures." Thesis, Rennes 1, 2013. http://www.theses.fr/2013REN1G022/document.

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La problématique de cette thèse est de comprendre et d’expliquer l’influence de l’activation des composantes périphérique efférente, expressive motrice et des sentiments subjectifs de l’émotion sur la formation des attitudes et des intentions comportementales du consommateur exposé à l’annonce. Cette recherche s’inscrit dans le modèle des processus composants de l’émotion développé en neurosciences affectives. Pour tester nos hypothèses, nous avons réalisé une étude selon laquelle les épisodes émotionnels du consommateur résultent de l’évaluation cognitive et dynamique des évènements mis en sc
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25

Elie, Dimitri. "Etude de la modulation des interactions corticomusculaires et intermusculaires induite par l'entraînement de force maximale chez le sujet sain." Thesis, Valenciennes, Université Polytechnique Hauts-de-France, 2021. https://ged.uphf.fr/nuxeo/site/esupversions/4ba833de-1ce6-410b-9e11-b04c2b2217a5.

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Les premières semaines d’entraînement conduisent à une augmentation rapide de la production de force maximale et/ou de la précision contrôle moteur. Ces adaptations comportementales sont supposées résulter d’adaptations neurophysiologiques puisque la structure musculaire reste inchangée. Ces adaptations neurophysiologiques pourraient être traduites par l’étude des mesures de cohérence corticomusculaire (CMC) et intermusculaire (IMC) qui désignent un niveau de corrélation entre l’activité oscillatoire du cortex moteur et musculaire. L’objectif de ce travail de thèse consiste à évaluer la reprod
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26

Khoubza, Lamyaa. "Régulation de l’assemblage et de l’activité des canaux potassiques de type K2P." Electronic Thesis or Diss., Université Côte d'Azur, 2020. http://theses.univ-cotedazur.fr/2020COAZ6042.

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Parmi les différentes familles de canaux potassiques, la famille des canaux à deux domaines pore, K2P, est la dernière à avoir été découverte à l’IPMC. Ces canaux sont responsables des courants dits « de fond » qui maintiennent le potentiel membranaire négatif réduisant ainsi l’excitabilité cellulaire. Les fonctions physiologiques qui dépendent de ces canaux sont nombreuses (transmission des messages nerveux, fonction cardiaque, homéostasie rénale, développement…). Ils ont été impliqués dans plusieurs conditions physiopathologiques (dépression, douleur, migraine…) et de ce fait, ils représente
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27

Novák, Karel. "Electrophysiological Models of Seizure like Activity for NO Detection in Vitro." Master's thesis, 2010. http://www.nusl.cz/ntk/nusl-276563.

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Definition of work: Electrophysiological models of seizure like activity for NO detection in vitro Supervisor: MUDr. Jakub Otáhal, PhD. Department of Anatomy and Biomechanics FTVS CUNI Department of Developmental Epileptology CAS, Institute of Physiology Consultant: Mgr. Renata Konopková Department of Developmental Epileptology CAS, Institute of Physiology Aim: The aim of the thesis is to introduce nitric oxide (NO) and its role in physiology and pathophysiolgy of central nervous system (CNS), with the intention of epileptiform activity in the nervous tissue. Our research was realized on rat h
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Pun, Carson. "In and Out of Consciousness: Sustained Electrophysiological Activity Reflects Individual Differences in Perceptual Awareness." Thesis, 2011. http://hdl.handle.net/1807/31395.

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Examining the neural correlates associated with the moment a stimulus enters or exits conscious awareness is one way to potentially identify the neural mechanisms that give rise to consciousness. In the present study, we examined neural activity using electroencephalogram (EEG) recordings while participants observed a bilateral shape-from-motion (SFM) display. While the display is in motion, the observer perceives an object that is immediately segregated from a noisy background. After the motion stops, the observer’s experience of the object remains momentarily in awareness, before it eventual
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29

Santamaria-Perez, Fidel. "Processing of mossy fiber activity in the cerebellar cortex : a combination of computer modeling and electrophysiological experiments." Thesis, 2001. https://thesis.library.caltech.edu/6120/1/Santamaria_f_2000.pdf.

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A combination of computer modeling and experimental approaches were taken to study tactile sensory processing in the cerebellar cortex. First, a detailed computer simulation of the cerebellar cortex was built. This model included the physiological properties of the different cells involved and their synaptic distributions. The model was used to study how a single tactile stimulus, arriving in the granule cell layer, is translated into Purkinje cell activity, the output of the cerebellar cortex. The model was also used to study the lack of beam-like Purkinje cell activation after a focal
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30

Chen, Jo-Tong, and 陳若佟. "Electrophysiological analysis of the spontaneous electrical activity for characterizing the sensitivity of myofascial trigger points of myofascial pain syndrome." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/55600586390677608772.

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博士<br>國立成功大學<br>醫學工程研究所<br>89<br>Myofascial pain syndrome (MPS), the most common cause of painful muscular dysfunction in clinics, is usually caused by or associated with obvious stress episode, repeated or sustained overload. Myofascial trigger point (MTrP), a hyperirritable spot within a palpable taut band of skeletal muscle, is the most important characteristic of MPS. Referred pain and local twitch response can be elicited by mechanical stimulus to the MTrP. MPS is suggested to represent a neuromuscular disorder and there are multiple active loci (dysfunctional motor end-plates) within an
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31

Chang, Jun-Hei, and 張俊喜. "Study of Epigallocatechin-3-gallate on the electrophysiological characteristics and the regulation mechanisms of arrhythmogenic activity on left atrium." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/pbsxrf.

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博士<br>國立臺灣科技大學<br>應用科技研究所<br>105<br>Atrial fibrillation (AF) is the commonest sustained arrhythmia, and gives rise to the risk of stroke, heart failure, and mortality. Many factors are considered to participate in the pathogenesis of AF, including calcium (Ca2+) overload and oxidative stress. Epigallocatechin-3-gallate (EGCG) has a well-know clinical effectiveness, such as an antioxidative potential to medical care, and has been shown to be beneficial in promoting cardiovascular health. However, it is still unclear whether EGCG directly modulates the electrophysiological characteristics and C
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32

Chen, Wan-Qi, and 陳婉琪. "Effects of LHRH and TRH on TIDA Neuron Activity and Prolactin Secretion in Ovariectomized, Estrogen-Treated Rats:A Neurochemical and Electrophysiological Study." Thesis, 1996. http://ndltd.ncl.edu.tw/handle/43049143283687797609.

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33

Yu-TingTseng and 曾鈺婷. "Cognitive Electrophysiological Performance on Visual Spatial Attention between Older Adults with Different Levels of Physical Activity—Using Soft Tennis as an example." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/41199372027391554329.

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34

Sousa, Sílvia Maria Vasconcelos. "Microglia-neuron interactions in the electrophysiological domain : can microglia respond directly to electrical signals?" Master's thesis, 2019. http://hdl.handle.net/10400.14/31508.

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A microglia é um tipo de célula com um comportamento dinâmico, que está constantemente a analisar a sua vizinhança e a alterar a sua morfologia para se adaptar ao microambiente onde está inserida. Apesar de serem conhecidas como células eletricamente não excitáveis, as funções da microglia parecem estar extremamente coordenadas com o estado funcional das redes neuronais, o que sugere a existência de uma íntima comunicação com os neurónios. Embora esta comunicação, através de sinais químicos, já ter sido alvo de muitos estudos, ainda não é claro se a microglia tem a capacidade de monitorizar o
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(8787026), Ka H. Ng. "Increased Neural Activity in the Prefrontal Cortex During Fear Suppression to a Safety Signal." Thesis, 2020.

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<p>Persistent and maladaptive fear in the absence of a threat can be disruptive because it decreases an organism’s opportunity to seek life-sustaining substances. Learned safety signaling can suppress fear and encourage reward-seeking behavior, thus freeing the organism from fear induced immobilization. The infralimbic (IL) region of the prefrontal cortex is important for recalling fear extinction memories and for suppressing fear via learned safety signals. Neurons in the IL show an excitatory response to an extinguished fear cue. We thus hypothesized that neurons in the IL would encode s
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Liu, Shiuh-Inn, and 劉絮穎. "Effect of hepatocyte growth factor on c-met expression, cell proliferation, cell cycle progression, cell motility and electrophysiological activity in human gastric cancer cells." Thesis, 1998. http://ndltd.ncl.edu.tw/handle/96767150213173256901.

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