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Journal articles on the topic 'Elephantopus scaber'

Author: Grafiati

Published: 5 June 2025

Last updated: 15 July 2025

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1

Solikin, Solikin. "Autekologi Elephantopus scaber L. di Kebun Raya Purwodadi." Bioeksperimen: Jurnal Penelitian Biologi 1, no. 1 (2015): 24–32. http://dx.doi.org/10.23917/bioeksperimen.v1i1.313.

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Elephantopus scaber adalah jenis tumbuhan berkhasiat obat yang banyak tumbuh liar di Kebun Raya Purwodadi. Penelitian yang bertujuan untuk mempelajari ekologi Elephantopus scaber di Kebun Raya Purwodadi dilakukan dengan mengamati iklim dan tanah serta komposisi jenis tumbuhan di sekitarnya. Untuk menentukan komposisi jenis pada komunitas tempat Elephantopus scaber maka dilakukan pengamatan pada lokasi : (a) penetrasi cahaya 100% (terbuka), (b) penetrasi cahaya 26-50% (agak terbuka) dan (c) penetrasi cahaya 5-25%(agak teduh). Analisis vegetasi pada masing-masing lokasi dilakukan dengan membuat

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2

Yulia, Mega, Yufri Aldi, Hansen Nasif, Fatma Sri Wahyuni, and Dachriyanus. "Immunoactivities of fractions of Elephantopus scaber linn leaf in NK cells, CD8+ T cells, and perforin." Prospects in Pharmaceutical Sciences 23, no. 1 (2025): 53–59. https://doi.org/10.56782/pps.304.

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The goal of this study is to determine the effect of a fraction of Elephantopus scaber Linn leaf extract on NK cells, CD8+ T cells, and perforin in male white mice using one dose of Elephantopus scaber Linn fraction at 30 mg/kg BW. In this study, 25 experimental animals were divided into 5 groups there are negative control, positive control, and 3 fractions of Elephantopus scaber Linn leaf, namely n-hexane, ethyl acetate, and butanol. Mice were treated with Elephantopus scaber Linn leaf fraction for 7 days after being previously stimulated by the SARS-Cov-2 virus antigen (inavac®). The animals

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3

Marina Silalahi. "Utilization of Elephantopus scaber as traditional medicine and its bioactivity." GSC Biological and Pharmaceutical Sciences 15, no. 1 (2021): 112–18. http://dx.doi.org/10.30574/gscbps.2021.15.1.0106.

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Elephantopus scaber has been used various ethnic groups in Indonesia and other countries as traditional medicine. Comprehensive study of the bioactivity of E. scaber is still limited, therefore this paper aims to explain the relationship between the use and its bioactivity. The writing of this article is based on a study of literature published online and offline used keywords E. scaber, bioactivities of E. scaber and uses of E. scaber. Ethnobotanically, E. scaber used to tread wound, nephritis, edema, chest pain, fever, scabies, sores, coughs, tonics, fever, and bronchitis, and asthma. The lo

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4

Marina, Silalahi. "Utilization of Elephantopus scaber as traditional medicine and its bioactivity." GSC Biological and Pharmaceutical Sciences 15, no. 1 (2021): 112–18. https://doi.org/10.5281/zenodo.4766820.

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<em>Elephantopus scaber</em> has been used various ethnic groups in Indonesia and other countries as traditional medicine. Comprehensive study of the bioactivity of <em>E. scaber</em> is still limited, therefore this paper aims to explain the relationship between the use and its bioactivity. The writing of this article is based on a study of literature published online and offline used keywords <em>E. scaber</em>, bioactivities of <em>E. scaber</em> and uses of <em>E. scaber</em>. Ethnobotanically, <em>E. scaber</em> used to tread wound, nephritis,

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5

Silalahi, Marina. "Pemanfaataan Tapak Liman (Elephantopus scaber) Sebagai Obat Tradisional dan Bioaktivitasnya." KESMAS UWIGAMA: Jurnal Kesehatan Masyarakat 7, no. 1 (2022): 16–29. http://dx.doi.org/10.24903/kujkm.v7i1.964.

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Elephantopus scaber (ES) atau yang dikenal juga sebagai tapak liman merupakan salah satu jenis tumbuhan obat tradisional yang telah dimanfaatkan berrbagai etnis di Indonesia maupun negara lain sebagai obat tradisional. Walaupun demikian kajian secara konfrehensif mengenai bioaktivitas ES masih terbatas, khususnya yang berbahasa Indonesia. Penulisan artikel ini didasarkan pada kajian literature yang terbit secara on line maupun off line dengan menggunakan beberapa kata kunci Elephantopus scaber, bioactivities of Elephantopus scaber dan uses of Elephantopus scaber. Secara etnobotani ES digunakan

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Hardiana, Hardiana, Yuni Dewi Safrida, Azmalina Adriani, and Saudah. "UJI DAYA HAMBAT EKSTRAK METANOL DAUN TAPAK LIMAN (Elephantopus scaber L) TERHADAP PERTUMBUHAN BAKTERI Escherichia coli." Jurnal Sains dan Kesehatan Darussalam 3, no. 2 (2023): 1–8. http://dx.doi.org/10.56690/jskd.v3i2.103.

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ABSTRAK Daun tapak liman (Elephantopus scaber L) dapat menghambat pertumbuhan bakteri karena mengandung senyawa metabolit sekunder seperti flavonoid, fenol, tannin, saponin, dan alkaloid, sehingga dapat mengobati penyakit diantaranya demam, malaria, batuk, disentri, dan diare. Pemberian antibakteri ekstrak methanol daun tapak liman merupakan salah satu cara untuk menghambat pertumbuhan bakteri Escherichia coli. Penelitian bertujuan untuk mengetahui diameter zona hambat (sekeliling daerah tersebut tidak ditumbuhi bakteri) dari ekstrak methanol antibakteri daun tapak liman (Elephantopus sc

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7

Than, Ni Ni, Serge Fotso, Madhumati Sevvana, et al. "Sesquiterpene Lactones from Elephantopus scaber." Zeitschrift für Naturforschung B 60, no. 2 (2005): 200–204. http://dx.doi.org/10.1515/znb-2005-0212.

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The ethanolic and acetone extracts of the whole plant of Elephantopus scaber were found to contain ethyl hexadecanoate, ethyl-9,12-octadecadienoate, ethyl-(Z)-9-octadecenoate, ethyl octadecanoate, lupeol, stigmasterol, stigmasterol glucoside, deoxyelephantopin (1) and two new germacranolide sesquiterpene lactones named 17,19-dihydrodeoxyelephantopin (2) and iso-17,19- dihydrodeoxyelephantopin (3) whose stereostructures were determined by spectroscopic methods, comparison with reported data and single-crystal X-ray analysis.

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8

Kabeer, Farha Arakkaveettil, and Remani Prathapan. "Phytopharmacological Profile of Elephantopus scaber." Pharmacologia 5, no. 8 (2014): 272–85. http://dx.doi.org/10.5567/pharmacologia.2014.272.285.

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9

Pui-Hay But, Paul, Po-Ming Hon, Hui Cao, et al. "Sesquiterpene lactones from Elephantopus scaber." Phytochemistry 44, no. 1 (1997): 113–16. http://dx.doi.org/10.1016/s0031-9422(96)00470-0.

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10

Zuo, Ai-Xue, Chun-Ping Wan, Xi Zheng, and Gao-Xiong Rao. "Chemical Constituents of Elephantopus scaber." Chemistry of Natural Compounds 52, no. 3 (2016): 484–86. http://dx.doi.org/10.1007/s10600-016-1680-x.

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11

Nguyen, Thi Thuy Nhien, Gia Huy Tran, Thi Hang Phung, Trong Hong Phuc Nguyen, and Tan Khang Do. "Genetic diversity of Elephantopus mollis H.B.K. and Elephantopus scaber L. based on DNA barcodes." INTERNATIONAL JOURNAL OF AGRICULTURE AND BIOLOGICAL SCIENCES 4, July & Aug 2020 (2020): 24–32. https://doi.org/10.5281/zenodo.4040905.

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<em>The study was conducted to compare the diversity of three sequences of DNA barcodes (atpF-atpH spacer, ITS region, and rbcL gene) of Elephantopus mollis H.B.K. and Elephantopus scaber L.. Three individuals were represented for each species and were collected at an indigenous location in Bay Nui area, An Giang province, Vietnam. The results showed that DNA barcodes were successfully amplified. The ITS and rbcL regions had no difference in the nucleotide sequences of samples in each species, except that atpF-atpH region had a difference at the 37th nucleotide position of E. mollis H.B.K. The

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Zendrato, Baby Cikita Lestari, Sri Wahyuni Nasution, Nursoleha Lubis, and Saharan R. Silaban. "Uji Aktivitas Antibakteri Ekstrak Etanol Daun Tapak Liman (Elephantopus Scaber L ) Terhadap Bakteri Shigella Dysenteriae Dengan Metode Difusi Cakra,." Biospecies 14, no. 1 (2021): 18–23. http://dx.doi.org/10.22437/biospecies.v14i1.11235.

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Penyakit disentriÂ merupakan peradangan pada usus yang disebabkan oleh bakteri shigella dan dapat menimbulkan gangguan fisiologis tubuh sehingga penyakit iniÂ menjadi masalah kesehatan yang perlu untuk diperhatikan. Daun Tapak Liman ( Elephantopus Scaber L ) mengandung senyawa flavonoid yang tinggi, fenol dan saponin yang dilaporkan memiliki antioksidan, antibakteri, antivirus dan antiradang. Penelitian ini bertujuan untuk mengetahui aktivitas ekstrak etanol daun tapak liman ( Elephantopus Scaber L ) Â sebagai antibakteri dan untuk mengetahui nilai kadar bunuh minimal untuk bakteri Shigella sp

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13

Mediterranean, Journal of Pharmacy and Pharmaceutical Sciences. "Evaluation of antimicrobial, antioxidant, antidiabetic activities, and acute toxicity of Elephantopus scaber L." Mediterranean Journal of Pharmacy and Pharmaceutical Sciences 5, no. 2 (2025): 87–95. https://doi.org/10.5281/zenodo.15365040.

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<em>Elephantopus scaber</em> L., a medicinal plant from Myanmar, was studied to evaluate its biological activity. The activity of antimicrobial assessment showed that ethyl acetate extract exhibited moderate activity in contrast to all six tested organisms. Using the 2,2-Diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging assay with ascorbic acid as standard for antioxidant activity showed that ethyl acetate extract possessed 36.28 μg/mL. The <em>in vivo</em> antidiabetic activity with glipizide, as a standard hypoglycemic agent was employed to determine antidiabetic activity. The data

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14

Sulistiarini, Riski, Anggi Puranti, and Wisnu Prabowo. "Phytochemicals and anti-hemorrhoidal activities Tapak Liman (Elephantopus scaber) leaves." Journal of Advanced Biotechnology and Experimental Therapeutics 6, no. 2 (2023): 436. http://dx.doi.org/10.5455/jabet.2023.d139.

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Hemorrhoids occur due to inflammation of the rectoanal venous plexus, which causes inflammation, pain, and can cause lumps. This inflammation can cause difficulty in defecation and can even cause heavy bleeding. Empirically Tapak Liman (Elephantopus scaber) leaves have been used to treat hemorrhoids and have been known to contain flavonoids and terpenoid lactones which are active as an anti-inflammatory. Objective: To determine the anti hemorrhoidal activity of E. scaber leaves in reducing inflammation in hemorrhoids in Wistar rats. Material and method: The research begins with the extraction

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Anuar, Fatin Nurul Ain, Muhammad Aiman Syafiq Zamri, Sharir Aizat Kamaruddin, Saiful Effendi Syafruddin, and Ahmad Suhail Khazali. "Antioxidant, Anti-Tyrosinase, and Anti-Collagenase Properties of Elephantopus scaber Leaf and Root Extracts." Science Letters 19, no. 2 (2025): 78–90. https://doi.org/10.24191/scl.v19i2.6905.

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Excessive exposure to ultraviolet (UV) radiation is the most common cause of accelerated skin aging. Due to the geographical location, skin aging has become a growing health concern in Malaysia, leading to the ever-increasing demand for skincare products. However, some skin care products contain hazardous chemicals such as paraben and formaldehyde. Thus, consumers are now switching to natural-based skincare products. Elephantopus scaber (E. scaber), also known as "Tutup Bumi", is one of the medicinal herbs found in Malaysia. Although E. scaber is widely used for medicinal purposes, its anti-sk

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16

Wanga, Li, Shuguang Jian, Peng Nan, and Yang Zhong. "Chemical Composition of the Essential Oil of Elephantopus scaber from Southern China." Zeitschrift für Naturforschung C 59, no. 5-6 (2004): 327–29. http://dx.doi.org/10.1515/znc-2004-5-606.

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The essential oil of Elephantopus scaber, a famous medicinal herb from Yangjiang County in Southern China was analyzed for the first time using GC-MS. The major constituents were hexadecanoic acid (42.3%), isopropyl dimethyl tetrahydronaphthalenol (14.1%), β-sesquiphellandrene (8.3%), octadecadienoic acid (5.5%), and phytol (5.2%).

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17

Nguyen, Trong Hong Phuc, and Thanh Dat Phan. "A Study on Antibacterial, Antioxidant, and Hepatoprotective Efficacy of Elephantopus scaber L." Sains Malaysiana 51, no. 12 (2022): 4031–41. http://dx.doi.org/10.17576/jsm-2022-5112-13.

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Elephantopus scaber is an herb widely used in folk remedies in Vietnam, especially in the treatment of liver disease. However, scientific studies evaluating the activity and ability to treat the disease in a scientific way are still very limited. This study evaluated the antibacterial, antioxidant, acute toxicity and hepatoprotective efficacy of E. scaber extracts. The extracts restricted the growth of 6 types of bacteria, being particularly most effective against E. coli. It was found that the E. scaber leaves extract was more efficient than root, stem, flower, and whole plant extracts. DPPH

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Bai, Ming, Jing-Jie Chen, Wei Xu, et al. "Germacranolides from Elephantopus scaber L. and their cytotoxic activities." Phytochemistry 178 (October 31, 2020): 1–8. https://doi.org/10.1016/j.phytochem.2020.112479.

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Bai, Ming, Chen, Jing-Jie, Xu, Wei, Dong, Shu-Hui, Liu, Qing-Bo, Yao, Guo-Dong, Lin, Bin, Huang, Xiao-Xiao, Song, Shao-Jiang (2020): Germacranolides from Elephantopus scaber L. and their cytotoxic activities. Phytochemistry (112479) 178: 1-8, DOI: 10.1016/j.phytochem.2020.112479, URL: http://dx.doi.org/10.1016/j.phytochem.2020.112479

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Yuliani, Yuliani. "Bioactivity effect of Elephantopus scaber Linn. extracts against Spodoptera litura and the soil microbial community." Revista de Ciências Agroveterinárias 21, no. 3 (2022): 206–15. http://dx.doi.org/10.5965/223811712132022206.

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This study investigates the biopesticidal effects of Elephantopus scaber Linn. extract on mortality of Spodoptera litura, Plutella xylostella, and non-target organisms and investigate the impact on S. litura protein levels and soil microbial community structure. The experiment was performed using a completely randomized design. Methanol extracts from E. scaber leaves, at concentrations of 2%, 4%, 6%, 8%, 10%, and 12%, were tested for bioactivity against the 2nd-instar larva of S. litura, P. xylostella, and earthworms. Mortality rates of the larvae and worms were observed. The collected data we

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Junairiah, Junairiah, Diah Ayu Wulandari, Edy Setiti Wida Utami, and Nabilah Istighfari Zuraidassanaaz. "Callus induction and secondary metabolite profile from Elephantopus scaber L." Journal of Tropical Biodiversity and Biotechnology 6, no. 1 (2021): 59234. http://dx.doi.org/10.22146/jtbb.59234.

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Elephantopus scaber L. is a plant that has potential as traditional medicine. Callus induction and production of secondary metabolite content can be increased by culture callus using plant growth regulators. This study was purposed to investigate the effect of IBA and kinetin concentration on the induction and secondary metabolite profile of callus from E. scaber L. leaves. Leaves explant of E. scaber L. were cultured on MS medium with various combination concentrations of IBA and kinetin for 6 weeks and then callus was extracted using methanol. Secondary metabolite content from the resulting

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Asfi, Nida, Yuyun Ika Christina, Dinia Rizqi Dwijayanti, Muhaimin Rifa’i, and Muhammad Sasmito Djati. "Anti-inflammatory Activity of Elephantopus scaber and Sauropus androgynus Combination in Pregnant Mice Infected with Escherichia coli." Journal of Experimental Life Sciences 12, no. 3 (2022): 117–23. http://dx.doi.org/10.21776/ub.jels.2022.012.03.06.

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The current study aimed to investigate the effectiveness of Elephantopus scaber and Sauropus androgynus as anti-inflammatory agents in pregnant mice infected with Escherichia coli. This study used seven treatments group (n=3): K- (healthy pregnant mice), K+ (pregnant mice infected with E. coli), P1 (pregnant mice infected with E. coli + E. scaber 100%), P2 (pregnant mice infected with E. coli + E. scaber 75% and S. androgynus 25%), P3 (pregnant mice infected with E. coli + E. scaber 50% and S. androgynus 50%), P4 (pregnant mice infected with E. coli + E. scaber 25% and S. androgynus 75%), P5 (

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Xu, Wei, Ming Bai, De-Feng Liu, et al. "MS/MS-based molecular networking accelerated discovery of germacrane-type sesquiterpene lactones from Elephantopus scaber L." Phytochemistry 198 (June 30, 2022): 1–11. https://doi.org/10.1016/j.phytochem.2022.113136.

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Xu, Wei, Bai, Ming, Liu, De-Feng, Qin, Shu-Yan, Lv, Tian-Ming, Li, Qian, Lin, Bin, Song, Shao-Jiang, Huang, Xiao-Xiao (2022): MS/MS-based molecular networking accelerated discovery of germacrane-type sesquiterpene lactones from Elephantopus scaber L. Phytochemistry (113136) 198: 1-11, DOI: 10.1016/j.phytochem.2022.113136, URL: http://dx.doi.org/10.1016/j.phytochem.2022.113136

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Lin, Chun-Ching, Ming-Hong Yen, and Hui-Fen Chiu. "The Pharmacological and Pathological Studies on Taiwan Folk Medicine (VI): The Effects of Elephantopus scaber subsp. oblanceolata, E. mollis and Pseudoelephantopus spicatus." American Journal of Chinese Medicine 19, no. 01 (1991): 41–50. http://dx.doi.org/10.1142/s0192415x91000065.

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The liver protective effect of Elephantopus scaber subsp. oblanceolata, E. mollis and Pseudoelephantopus spicatus on CCL 4 induced hepatotoxicity has been determined by liver enzyme functional test and pathological studies. As the result indicatep, the acute increase of serum transaminase (SGOT and SGPT level which was caused by CCL 4 administration (3.0ml/kg, s.c.) can be significantly reduced when treating with E. scaber subsp. oblanceolata( p < 0.001), E. mollis( p < 0.01), P. spicatus( p < 0.01). The hepatic fatty metamorphosis and necrosis of central lobule were obviously improve

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Aldi, Yufri, Megaraswita, and Dwisari Dillasamola. "Effect of Elephantopus Scaber Linn. leaf extract on mouse immune system." Tropical Journal of Pharmaceutical Research 18, no. 10 (2021): 2045–50. http://dx.doi.org/10.4314/tjpr.v18i10.7.

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Purpose: To investigate the effect of Elephantopus Scaber Linn. ethanol extract on mouse immune system based on macrophage phagocytic activity and capacity, total leukocyte count, and distribution of each type of leukocyte. Methods: Twenty male mice were randomly assigned to four groups. Group I (control) received sodium carboxy methyl cellulose (Na-CMC), 0.5 %). Groups II, III, and IV were dosed orally with 10, 30, and 100 mg/kg ethanol E. scaber leaf extract, respectively, for 7 consecutive days. On the 8th day, a suspension of Staphylococcus aureus was injected intraperitoneally, and

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Ho, Wan Yong, Sok Sian Liew, Swee Keong Yeap, and Noorjahan Banu Alitheen. "Synergistic Cytotoxicity between Elephantopus scaber and Tamoxifen on MCF-7-Derived Multicellular Tumor Spheroid." Evidence-Based Complementary and Alternative Medicine 2021 (October 19, 2021): 1–15. http://dx.doi.org/10.1155/2021/6355236.

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Elephantopus scaber Linn, a traditional herb, exhibited anticancer properties, and it was cytotoxic against the monolayer estrogen receptor-positive breast cancer cell line, MCF-7, in the previous study. In order to determine the potential of E. scaber as a complementary medicine for breast cancer, this study aimed to evaluate the synergism between E. scaber and tamoxifen in cytotoxicity using MCF-7 in the form of 3-dimensional multicellular tumor spheroid (MCTS) cultures. MCTS represents a more reliable model for studying drug penetration as compared to monolayer cells due to its greater rese

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Djati, Muhammad Sasmito, Dinia Rizqi Dwijayanti, and Muhaimin Rifa’i. "Herbal supplement formula of Elephantopus scaber and Sauropus androgynus promotes IL-2 cytokine production of CD4+T cells in pregnant mice with typhoid fever." Open Life Sciences 11, no. 1 (2016): 211–19. http://dx.doi.org/10.1515/biol-2016-0029.

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AbstractProduction of IL-2 by CD4+ T cells is shown to be suppressed in pregnant women infected by bacteria such as Salmonella typhi. Elephantopus scaber and Sauropus androgynus may be used as herbal supplement to ameliorate this condition. This study aimed to investigate the efficacy of E. scaber and S. androgynus formulation to promote lymphoid proliferation and CD4 cytokine productions. The pregnant mice were randomly divided into seven experimental groups: K- (control), K+ (with S. typhi), P1 (S. typhi + E. scaber 100%), P2 (S. typhi E. scaber 75% and S. androgynus 25%), P3 (S. typhi+ E. s

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Hiradeve, Sachin Marotrao, and Vinod D. Rangari. "Antibacterial and antifungal activities of Elephantopus scaber Linn." International Journal of Biomedical Research 6, no. 5 (2015): 338. http://dx.doi.org/10.7439/ijbr.v6i5.2106.

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N.T.H., Phuc,, Hang, P.T., Dat, P.T., Nhien, N.T.T., and Khang, D.T. "Acute toxicity, antibacterial and antioxidant abilities of Elephantopus mollis H.B.K. and Elephantopus scaber L." Can Tho University Journal of Science Vol.12(2) (2020): 9. http://dx.doi.org/10.22144/ctu.jen.2020.010.

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Bhusan Sahoo, Himanshu, Rakesh Sagar, Subrat Kumar Bhattamisra, and Amrita Bhaiji. "Preliminary study on the impact of methanolic extract of Elephantopus scaber Linn. on hair growth promoting effect in rats." Herba Polonica 59, no. 2 (2013): 35–45. http://dx.doi.org/10.2478/hepo-2013-0010.

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Summary Methanolic extract of Elephantopus scaber leaves was investigated for its role in hair growth in experimental rats. The 2% and 5% solution of prepared formulation using methanolic extract was studied for hair growth on wistar rats for 30 days. Minoxidil (2% solution) was taken as a reference standard. The prepared hair oil formulation of methanolic extract significantly (p<0.01) potentiated the hair growth initiation and completion time with dosedependent improvement in skin biopsy, hair length and hair weight. In vitro hair follicles development study showed the significant (p<0

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Isnawati, Fitriari Izzatunnisa Muhaimin, and Ahmad Fudhaili. "Tapak Liman (Elephantopus scaber) crude extract induces polyploidy in shallot root (Allium cepa war ascalonium (L))." E3S Web of Conferences 513 (2024): 03011. http://dx.doi.org/10.1051/e3sconf/202451303011.

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This study investigates the impact of induction time and concentration of Tapak Liman (Elephantopus scaber) crude extract on the effectiveness of polyploidy in shallot root (Allium cepa var ascalonium (L). Several parameters were observed, including the mitotic index of cells, the type of polyploidy, percentages of polyploidy cells, and the morphological changes in the polyploid shallot root (Allium cepa var ascalonium (L)) cell. Variations in the concentration of Elephantopus scaber extract were used namely 0% (control), 10%, 20%, and 30% in 100 ml of distilled water. The response variable wa

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Abraham, Jyothi, and T. Dennis Thomas. "An efficient shoot regeneration system for medicinally important Elephantopus scaber Linn." Crop Breeding and Applied Biotechnology 15, no. 2 (2015): 94–99. http://dx.doi.org/10.1590/1984-70332015v15n2a17.

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An efficient protocol for the rapid micropropagation of medicinally important Elephantopus scaber has been standardized using cotyledonary node explants. Direct multiple shoot induction was observed when the cotyledonary node explants at various age groups were cultured on MS medium supplemented with various plant growth regulators. The highest shoot induction was obtained when the cotyledonary node explants from 20-day-old seedlings were cultured on MS medium supplemented with 1.5 mg L-1 TDZ and 0.5 mg L-1 NAA. On this medium, 98% of the cultures responded, with an average number of 33.7 shoo

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Fajrin, Dessy Hidayati, Lydia Febri Kurniatin, and Tessa Siswina. "PENGARUH TAPAK LIMAN (Elephantopus scaber) TERHADAP INTENSITAS DISMENORE PADA REMAJA PUTERI." Jurnal Kebidanan Khatulistiwa 10, no. 2 (2024): 104. https://doi.org/10.30602/jkk.v10i2.1353.

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Menstrual pain (dysmenorrhea) can have an impact on the activities or activities of women, especially teenagers. If dysmenorrhea is not treated immediately, it will affect the mental and physical function of the individual, it is urgent to take pharmacological or non-pharmacological action immediately. One of the plants that can be used as traditional medicine is Tapak Liman (Elephantopus scaber). Tapak Liman contains the flavonoid luteolin-7-glikosida stigmasterol, isodeoxyelephantopin, elephantopin, deoxyelephantopin, epiprielinol which have natural analgesic and anti-inflammatory effects. D

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Daisy, P., and Cecilia Edel Priya. "Hypolipidemic and Renal Functionality Potentials of the Hexane Extract Fractions of Elephantopus Scaber Linn." International Journal of Biomedical Science 6, no. 3 (2010): 241–45. http://dx.doi.org/10.59566/ijbs.2010.6241.

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Background: Abnormalities in lipid profile are one of the most common complications in diabetes mellitus. In STZ -induced diabetic rats, the rise in blood glucose is accompanied by a disturbance in lipid profile. Further still is the disturbance in the renal functions which includes abnormality in the serum urea,protein and creatinine levels The aim of the present study is to prove the hypolipidemic and the renal functionality effect of the root of Elephantopus scaberLinn. Procedure: Fractions obtained from crude extracts of hexane prepared from the root of Elephantopus scaberLinn. were admini

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Bhaiji, Amrita, SubratKumar Bhattamisra, PravatKusum Mandal, Rakesh Sagar, and HimanshuBhusan Sahoo. "A new weapon for memory power: Elephantopus scaber (Linn.)." International Journal of Nutrition, Pharmacology, Neurological Diseases 4, no. 1 (2014): 64. http://dx.doi.org/10.4103/2231-0738.124616.

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Bai, Ming, Jing-Jie Chen, Wei Xu, et al. "Germacranolides from Elephantopus scaber L. and their cytotoxic activities." Phytochemistry 178 (October 2020): 112479. http://dx.doi.org/10.1016/j.phytochem.2020.112479.

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Wu, Taizong, Hui Cui, Bao Cheng, Sai Fang, Jun Xu, and Qiong Gu. "Chemical constituents from the roots of Elephantopus scaber L." Biochemical Systematics and Ecology 54 (June 2014): 65–67. http://dx.doi.org/10.1016/j.bse.2013.12.012.

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Tripathi, S. C., and Manjulla Srivastava. "Elephantopus scaber L. - A traditional panacea for several ailments." Environment Conservation Journal 9, no. 1&2 (2008): 81–82. http://dx.doi.org/10.36953/ecj.2008.091216.

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The role of natural products, herbal medicines, and traditional medicines is being increasing in the recent years for the prevention and management of human disorders. The present paper deals with ethnomedicinal use of Elephantopus scaber L. collected from Nishangada forest (Kakraha range) of Bahraich, a tarai district of eastern U.P. India. During field survey on 5 August 2006 and 2 January 2007, out of many collected plants we got the information about a herbaceous flora locally called as "Hastipata" by tribal peoples. These tribals are the migrants of Nepal in Nishangada forest (Kakraha ran

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Leenutaphong, Petchpailin, Salunya Tancharoen, Thamthiwat Nararatwanchai, et al. "Induction of Human Oral Squamous Carcinoma Apoptosis by Derris scandens Benth and Elephantopus scaber Linn Extracts." Natural Product Communications 17, no. 6 (2022): 1934578X2211079. http://dx.doi.org/10.1177/1934578x221107970.

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D scandens ( Derris scandens Benth.) and E scaber ( Elephantopus scaber Linn.) contain flavonoids and phenolic acids, which have antitumor activity in various cancer cell lines. Oral cancer is among the most common cancers in Southeast Asia, and the survival rate remains low. Thus, this study screened 2 ethanolic plant extracts for cytotoxicity on the oral human squamous carcinoma cell line (HSC-2), and compared the mechanisms of action. Extracts of D scandens and E scaber showed cytotoxicity against HSC-2 cells in a dose-dependent manner. Observation of nuclear morphology by Hoechst 33342 sta

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Kelik, Marmi. "Tapak Liman (Elephantopus scaber L) As Immunostimulant and Its Effect on Lymphocyte Differentiation in Mice BALB/C." Biology, Medicine, & Natural Product Chemistry 4, no. 2 (2015): 49. http://dx.doi.org/10.14421/biomedich.2015.42.49-51.

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<p>Tapak liman (<em>Elephantopus scaber </em>L) is one of the plants that have medicinal properties and has been used for maintenance and improvement of health and disease treatment. The purpose of this study was to determine the effect of extracts of Tapak Liman (Elephantopus scaber L) as immunostimulant to the development of lymphocytes in mice BALB / C. The procedure of this study was to test aqueous extracts in vivo with various treatments (control, treatment of 0.5 g / kg, 1.0 g/ kg, 2.0 g / kg) in healthy mice BALB / C for 2 weeks. After the treatment carried out analys

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Wu, Ze-Ming, Mei-Ya Lian, Xiao-Yu Han, Ming Bai, and Shao-Jiang Song. "Chemical constituents from Elephantopus scaber L. and their chemotaxonomic significant." Biochemical Systematics and Ecology 116 (October 2024): 104871. http://dx.doi.org/10.1016/j.bse.2024.104871.

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Hiradeve, Sachin, and Vinod Rangari. "Immunomodulatory Study of Different Solvent Extract of Elephantopus scaber Linn." Drug Research 67, no. 04 (2017): 239–43. http://dx.doi.org/10.1055/s-0042-124357.

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Hiradeve, Sachin M., and Vinod D. Rangari. "A review on pharmacology and toxicology of Elephantopus scaber Linn." Natural Product Research 28, no. 11 (2014): 819–30. http://dx.doi.org/10.1080/14786419.2014.883394.

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Dewi, Ratna Sari, and Dadang Dadang. "Aktivitas biologi enam jenis ekstrak tumbuhan famili Asteraceae terhadap larva Spodoptera litura Fabricius (Lepidoptera: Noctuidae)." Jurnal Entomologi Indonesia 2, no. 1 (2017): 51. http://dx.doi.org/10.5994/jei.2.1.51.

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Biological Activity of Six Plan Extract from Asteraceae on Spodoptera litura Fabricius (lipedoptera : Noctuidae) Larvae. Asteraceae is one of plant family that is known to have insecticidal activity to several insect pests, such as Parthenium argentatum, Crysanthemum cineariaefolium, and Agerantum houstoneanum. The aim of this study is to explore other asteraceae species in other to search for insecticidal activity to Spodoptera litura Fabricius (Lepidoptera: Noctuidae). Six species, Blumea balsamifera (leaf), Elephantopus scaber (leaf), Gynura procumbens (leaf) Artemisia vulgaris (leaf) Soncb

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Sandra, Ferry, Ria Aryani Hayuningtyas, Dewi Ranggaini, Tiffany Pang, Alifah Evi Scania, and Kyung Hoon Lee. "Elephantopus scaber Linn. Leaf Extract Sensitizes Doxorubicin in Inducing Apoptosis in HSC-3 Tongue Cancer Cells through Inhibiting Survivin Activity at Thr34." Indonesian Biomedical Journal 16, no. 4 (2024): 372–8. http://dx.doi.org/10.18585/inabj.v16i4.3096.

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BACKGROUND: Previous research has demonstrated the effect of Elephantopus scaber Linn. leaf extract (ESLE) on various cancer cell lines. However, research on the effects of ESLE on oral squamous cell carcinoma (OSCC), especially tongue cancer, is still lacking. Moreover, the apoptotic mechanisms induced by ESLE are not well understood and require further exploration. Therefore, this study was conducted to investigate the effects of ESLE on cell viability and apoptosis in human squamous cell carcinoma (HSC)-3 tongue cancer cells.METHODS: HSC-3 cells were treated with varying concentrations of E

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Zailani, Mohd Alhafiizh, and Fasihuddin Badruddin Ahmad. "The Oils from Stems, Leaves and Roots of Elephantopus scaber Linn." Borneo Journal of Resource Science and Technology 6, no. 1 (2016): 46–49. http://dx.doi.org/10.33736/bjrst.214.2016.

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The oil from stems, leaves and roots of Elephantopus scaber Linn. were extracted by solvent macerationtechnique. The percentage yield oil from stems, leaves and roots are 0.001%, 0.003% and 0.04%, respectively.The stem oil gives major constituents of pentacosane (12.3%), lupenyl acetate (11.7%) and fern-7-en-3β-ol(11.0%), while the leaf oil contains isooctyl phthalate (19.2%), hexadecanoic acid (15.0%) and α-linolenic acid(5.0%) as the major components. The major constituents identified in the root oil are hemellitol (11.6%), octylphthalate (6.0%), 1-nonadecanol (5.6%) and 1-octadecanol (5.5%)

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Kurnia, Bella, Muhtarudin Muhtarudin, Dian Septinova, and Sri Suharyati. "PENGARUH PEMBERIAN TAPAK LIMAN (Elepanthopus Scaber L.) DALAM AIR MINUM TERHADAP TOTAL ERITROSIT, HEMOGLOBIN, DAN HEMATOKRIT BROILER." Jurnal Riset dan Inovasi Peternakan (Journal of Research and Innovation of Animals) 6, no. 4 (2022): 368–74. http://dx.doi.org/10.23960/jrip.2022.6.4.368-374.

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Penelitian ini bertujuan untuk mengetahui pengaruh dan pemberian dosis terbaik Tapak Liman (Elephantopus scaber L.) terhadap profil darah merah (total eritrosit, hemoglobin, dan hematokrit) broiler. Penelitian ini dilaksanakan pada Februari—Maret 2022 di kandang ayam, Jurusan Peternakan, Fakultas Pertanian, Universitas Lampung dan Laboratorium Fakultas Kedokteran Hewan, Universitas Gadjah Mada, Yogyakarta. Penelitian menggunakan metode Rancangan Acak Lengkap (RAL) dengan 4 perlakuan 3 ulangan. Tapak Liman yang diberi melalui air minum dengan dosis kontrol (P0), 120 mg/kg BB/hari (P1), 240 mg/k

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Mehmood, Tahir, and Chatchai Muanprasat. "Deoxyelephantopin and Its Isomer Isodeoxyelephantopin: Anti-Cancer Natural Products with Multiple Modes of Action." Molecules 27, no. 7 (2022): 2086. http://dx.doi.org/10.3390/molecules27072086.

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Cancer is a leading cause of morbidity and mortality worldwide. The development of cancer involves aberrations in multiple pathways, representing promising targets for anti-cancer drug discovery. Natural products are regarded as a rich source for developing anti-cancer therapies due to their unique structures and favorable pharmacology and toxicology profiles. Deoxyelephantopin and isodeoxyelephantopin, sesquiterpene lactone compounds, are major components of Elephantopus scaber and Elephantopus carolinianus, which have long been used as traditional medicines to treat multiple ailments, includ

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Tsai, Chin-Chuan, Jia-Ping Wu, Yueh-Min Lin, et al. "The Effect ofElephantopus scaber L.on Liver Regeneration after Partial Hepatectomy." Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–11. http://dx.doi.org/10.1155/2013/369180.

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Liver regeneration after partial hepatectomy (PHx) is a physiological response for maintaining homeostasis. The aim of this study is to investigate effects ofElephantopus scaber L.-(ESL-) induced liver regeneration on growth factors (HGF and IGF-1), cell cycle regulation, and apoptosis suppressed. In this study, we fed five Chinese medicinal herbs (1 g/kg/day),Codonopsis pilosula(CP, Dangshen),Salvia miltiorrhiza Bunge(SMB, Danshen,),Bupleurum kasi(BK, Chaihu),Elephantopus scaber L.(ESL, Teng-Khia-U), and Silymarin (Sm, 25 mg/kg) for 7 days to male Spraue-Dawley rats. Then surgical 2/3 PHx was

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Wang, Jianjun, Ping Li, Baosai Li, Zhiyong Guo, Edward J. Kennelly, and Chunlin Long. "Bioactivities of Compounds fromElephantopus scaber, an Ethnomedicinal Plant from Southwest China." Evidence-Based Complementary and Alternative Medicine 2014 (2014): 1–7. http://dx.doi.org/10.1155/2014/569594.

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Elephantopus scaberis an ethnomedicinal plant used by the Zhuang people in Southwest China to treat headaches, colds, diarrhea, hepatitis, and bronchitis. A newδ-truxinate derivative, ethyl, methyl 3,4,3′,4′-tetrahydroxy-δ-truxinate (1), was isolated from the ethyl acetate extract of the entire plant, along with 4 known compounds. The antioxidant activity of these 5 compounds was determined by ABTS radical scavenging assay. Compound1was also tested for its cytotoxicity effect against HepG2 by MTT assay (IC50=60 μM), and its potential anti-inflammatory, antibiotic, and antitumor bioactivities w

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Nurtamin, Tomy, I. Putu Sudayasa, and Tien. "In Vitro Anti-Inflammatory Activities of Ethanolic Extract Elephantopus Scaber Leaves." Jurnal Kedokteran dan Kesehatan Indonesia 9, no. 1 (2018): 46–52. http://dx.doi.org/10.20885/jkki.vol9.iss1.art9.

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