Academic literature on the topic 'Elocalcitolo'

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Journal articles on the topic "Elocalcitolo"

1

Morelli, Annamaria, Roberta Squecco, Paola Failli, et al. "The vitamin D receptor agonist elocalcitol upregulates L-type calcium channel activity in human and rat bladder." American Journal of Physiology-Cell Physiology 294, no. 5 (2008): C1206—C1214. http://dx.doi.org/10.1152/ajpcell.90634.2007.

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Human bladder contraction mainly depends on Ca2+ influx via L-type voltage-gated Ca2+ channels and on RhoA/Rho kinase contractile signaling, which is upregulated in overactive bladder (OAB). Elocalcitol is a vitamin D receptor agonist inhibiting RhoA/Rho kinase signaling in rat and human bladder. Since in the normal bladder from Sprague-Dawley rats elocalcitol treatment delayed the carbachol-induced contraction without changing maximal responsiveness and increased sensitivity to the L-type Ca2+ channel antagonist isradipine, we investigated whether elocalcitol upregulated L-type Ca2+ channels
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2

Borgogni, E., E. Sarchielli, M. Sottili, et al. "Elocalcitol Inhibits Inflammatory Responses in Human Thyroid Cells and T Cells." Endocrinology 149, no. 7 (2008): 3626–34. http://dx.doi.org/10.1210/en.2008-0078.

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T-helper 1 (Th1) cell-mediated inflammatory responses predominate in the early pathogenesis of Graves’ disease (GD), whereas Th2 cell-mediated immunity may play a role in later stages. The chemokine CXCL10 and its receptor CXCR3 are expressed in most thyroid glands of early GD patients. Circulating CXCL10 levels inversely correlate with disease duration; CXCL10 maximal expression also correlates with interferon (IFN)γ levels in recent GD onset. Methimazole (MMI) reduces CXCL10 secretion by isolated thyrocytes, decreases serum CXCL10 levels, and promotes a transition from Th1 to Th2 dominance i
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3

Revill, P., N. Serradell, and J. Bolós. "Elocalcitol." Drugs of the Future 31, no. 12 (2006): 1042. http://dx.doi.org/10.1358/dof.2006.031.12.1060203.

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4

&NA;. "Elocalcitol beneficial for benign prostatic hyperplasia." Inpharma Weekly &NA;, no. 1610 (2007): 8. http://dx.doi.org/10.2165/00128413-200716100-00015.

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&NA;. "BXL 628* [Elocalcitol] is effective in the treatment of overactive bladder,." Inpharma Weekly &NA;, no. 1538 (2006): 6. http://dx.doi.org/10.2165/00128413-200615380-00015.

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6

Streng, T., K. E. Andersson, P. Hedlund, et al. "548 ELOCALCITOL IMPROVES EFFECTS BY TOLTERODINE IN RATS WITH PARTIAL URETHRAL OBSTRUCTION." European Urology Supplements 10, no. 2 (2011): 181–82. http://dx.doi.org/10.1016/s1569-9056(11)60539-3.

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7

Streng, Tomi, Karl-Erik Andersson, Petter Hedlund, et al. "Effects on bladder function of combining elocalcitol and tolterodine in rats with outflow obstruction." BJU International 110, no. 2b (2012): E125—E131. http://dx.doi.org/10.1111/j.1464-410x.2011.10838.x.

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8

Tiwari, Atul. "Elocalcitol (BXL-628): a novel, investigational therapy for the therapeutic management of benign prostatic hyperplasia." Expert Opinion on Investigational Drugs 17, no. 5 (2008): 819–24. http://dx.doi.org/10.1517/13543784.17.5.819.

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9

Adorini, Luciano, Giuseppe Penna, Susana Amuchastegui, et al. "Inhibition of prostate growth and inflammation by the vitamin D receptor agonist BXL-628 (elocalcitol)." Journal of Steroid Biochemistry and Molecular Biology 103, no. 3-5 (2007): 689–93. http://dx.doi.org/10.1016/j.jsbmb.2006.12.065.

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10

Montorsi, Francesco, and Enrico Colli. "ELOCALCITOL IN THE TREATMENT OF BPH: A MULTICENTER, RANDOMIZED, PLACEBO-CONTROLLED PHASE IIB CLINICAL TRIAL." Journal of Urology 179, no. 4S (2008): 700–701. http://dx.doi.org/10.1016/s0022-5347(08)62043-1.

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