Journal articles: 'Emmenagogues'

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Chen, Lena. "We Lived In The Gaps Between The Stories: Performing The Radical Care Work Of Abortion." Public 35, no. 69 (April 1, 2024): 53–56. http://dx.doi.org/10.1386/public_00187_1.

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This essay reflects upon the author’s experience creating a participatory artwork—a wreath made of abortifacients and emmenagogues—to honor the labor of abortion workers. Collaboratively made with public involvement, the piece was created in Cincinnati, Ohio against the backdrop of increasingly restrictive abortion laws.

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Sri D, Packia, and Kingsly A. "Comparative Study of Relation between Laxative and Emmenagogue Activity of Herbs Described in Gunapadam Mooligai." International Journal of Health Sciences and Research 11, no. 5 (May 7, 2021): 136–39. http://dx.doi.org/10.52403/ijhsr.20210520.

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Introduction: According to siddha system of medicine 10 vayu and 10 nadis are mainly consider for curing and producing disease among 10 vayu 2nd vayu known as abhana vayu action on laxative and emmenagogue herbs are described. Aim: To compare the relationship between laxative and emmenagogue activities of herbal drug prescribed in Gunapadam Molligal book. Method: A comparative study of relation between laxative and emmenogogue activity was done in herbs described in Gunapadam mooligai book. In the book the author has described 1535 herbs and their activity and they are co related Conclusion: Out of 40 herbs of emmenogogue activity 26 herbs having laxative activity in which 17 are laxative and 8 herbs are cathartic activity. Most of the drug with emmenogogue activity also having laxative activity. As the result emmenogogue activity of herbs are given along with laxative activity. The normal function of ABHANA VAYU will help in the normal function of uterur, urinary system and large intestine function. Key words: laxative, emmenagogue, siddha herb.

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Ali Esmail Al-Snafi. "The medical importance of Iris pallida – A review." International Journal of Biological and Pharmaceutical Sciences Archive 1, no. 2 (May 30, 2021): 190–96. http://dx.doi.org/10.30574/ijbpsa.2021.1.2.0046.

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Iris pallid (Family: Iridaceae) was used traditionally asantispasmodic, aperient, aromatic, attenuant, carminative, detoxicant, diuretic, emetic, emmenagogue, expectorant, fixative, laxative, pectoral, purgative and sedative. It contained oils and aromatic constituents, fat, resin, a large quantity of starch, mucilage, phenolics, flavonoids and glucosides. Iris pallida possessed many pharmacological effects included anti-inflammatory, antioxidant, anti-aging, anticancer, antiparasitic and antimicrobial activities. The current review will highlight the chemical constituents and pharmacological effects of Iris pallida.

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Jameel, Sana, Fahmeeda Zeenat, and Suboohi Mustafa. "Scientific appraisal of plant origin Emmenagogue and its therapeutics in unani medicine: A review." International Journal of Herbal Medicine 11, no. 6 (January 1, 2023): 03–09. http://dx.doi.org/10.22271/flora.2023.v11.i6a.907.

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Ulubelen, Ayhan, and Mehmet Öztürk. "Alkaloids and Coumarins from Ruta Species." Natural Product Communications 1, no. 10 (October 2006): 1934578X0600101. http://dx.doi.org/10.1177/1934578x0600101006.

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Although there are a number of Ruta species in the world, R. graveolens L., R. chalepensis L., R. montana (L.) L., R. angustifolia Pers. and R. pinnata L. fil. are the most studied. However, the first two of them have been the most extensively investigated for their chemical constituents and biological activities. They are used for their anthelmintic, diuretic, emmenagogue, and aphrodisiac properties. In dermatology, they are used against psoriasis and vitiligo, and as mycosis fungicides. In many countries, the plant extracts have been used as birth control agents.

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Asma Mohd Anis, Khan, Sultan Ul Haque, Mariya Fatema, and Mohammad Zakir. "SAKBEENAJ (FERULA PERSICA WILLD.): AN IMPORTANT DRUG OF UNANI SYSTEM OF MEDICINE." International Journal of Advanced Research 11, no. 10 (October 31, 2023): 421–26. http://dx.doi.org/10.21474/ijar01/17723.

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Since ancient times, the plant Ferula Persica Willd (Family - Apiaceae), also known as sakbeenaj, has been utilized in traditional medicinal system to cure a variety of ailments.Its descriptions as a Detergent,purgatives,diureticand emmenagoguein ethnomedical literature demonstrate the plants range of biological and pharmacological properties.It is used to treat DÄ«q al-Nafas (bronchial asthma), BawÄsÄ«r (Hemorrhoid) and HasÄh al-kulya (renal-stone).

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Chaudhary, Nirali, Jyoti Chauhan, and Bharat Maitreya. "A REVIEW ON BIOACTIVITY OF GRANGEA MADERASPATANA (L) POIR." International Association of Biologicals and Computational Digest 2, no. 1 (May 15, 2023): 230–33. http://dx.doi.org/10.56588/iabcd.v2i1.149.

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Grangea maderaspatana (L.) Poir., also known as Madras Carpet, is a medicinal flowering plant in the Asteraceae family. This is a common weed that grows in sandy soils and waste areas. This plant has produced a wide range of phytochemical substances. It has been used for thousands of years in traditional Ayurveda Indian medicine to treat a number of diseases. This plant has oestrogenicity, antifertility, analgesic, anti-inflammatory, antiarthritic, cytotoxic, antioxidant, hepatoprotective, diuretic, and antibacterial effects have all been studied. The leaves have stomachic, a sedative, carminative, emmenagogue, and antiflatulent properties. The review covers biological activity phytochemicals derived from these plants in detail.

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S.Tripathy and N.K.S Neeraja. "Evaluation of anxiolytic potential of Cichorium Intybus methanolic root extracts." Journal of Biomedical and Pharmaceutical Research 9, no. 6 (December 21, 2020): 25–30. http://dx.doi.org/10.32553/jbpr.v9i6.817.

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Cichorium Intybus L. is a medicinally important plant that belongs to the family Asteraceae. The plant root is used as anti-hepatotoxic, antiulcerogenic, antiinflammatory, appetizer, digestive, stomachic, liver tonic, cholagogue, cardiotonic, depurative, diuretic, emmenagogue, febrifuge, alexeteric and also as tonic. The present study was carried to screen the anxiolytic potential of Cichorium Intybus L methanolic root extracts by using different animal models like actophotometer, rotarod, staircase, holeboard, elevated plus maze tests . In the experiment the extracts found to decrease the anticipatory anxiety of the animal without significant alteration in motor coordination. Efficacy may be attributed to the presence of different phytochemicals like coumarins, flavonoids in the extracts.

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Moini Jazani, Arezoo, Kobra Hamdi, Mojgan Tansaz, Hossein Nazemiyeh, Homayoun Sadeghi Bazargani, Seyed Mohammad Bagher Fazljou, and Ramin Nasimi Doost Azgomi. "Herbal Medicine for Oligomenorrhea and Amenorrhea: A Systematic Review of Ancient and Conventional Medicine." BioMed Research International 2018 (2018): 1–22. http://dx.doi.org/10.1155/2018/3052768.

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Introduction. Menstrual bleeding cessation is one of the most frequent gynecologic disorders among women in reproductive age. The treatment is based on hormone therapy. Due to the increasing request for alternative medicine remedies in the field of women’s diseases, in present study, it was tried to overview medicinal plants used to treat oligomenorrhea and amenorrhea according to the pharmaceutical textbooks of traditional Persian medicine (TPM) and review the evidence in the conventional medicine. Methods. This systematic review was designed and performed in 2017 in order to gather information regarding herbal medications of oligomenorrhea and amenorrhea in TPM and conventional medicine. This study had several steps as searching Iranian traditional medicine literature and extracting the emmenagogue plants, classifying the plants, searching the electronic databases, and finding evidences. To search traditional Persian medicine references, Noor digital library was used, which includes several ancient traditional medical references. The classification of plants was done based on the repetition and potency of the plants in the ancient literatures. The required data was gathered using databases such as PubMed, Scopus, Google Scholar, Cochrane Library, Science Direct, and web of knowledge. Results. In present study of all 198 emmenagogue medicinal plants found in TPM, 87 cases were specified to be more effective in treating oligomenorrhea and amenorrhea. In second part of present study, where a search of conventional medicine was performed, 12 studies were found, which had 8 plants investigated: Vitex agnus-castus, Trigonella foenum-graecum, Foeniculum vulgare, Cinnamomum verum, Paeonia lactiflora, Sesamum indicum, Mentha longifolia, and Urtica dioica. Conclusion. Traditional Persian medicine has proposed many different medicinal plants for treatment of oligomenorrhea and amenorrhea. Although just few plants have been proven to be effective for treatment of menstrual irregularities, the results and the classification in present study can be used as an outline for future studies and treatment.

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Wani, Ghulam Nabi, Afifa Naaz, Wajeeha Begum, and Shavana Fathima. "Unani perspective of Saffron (Crocus sativus Linn.) beyond a spice." Journal of Drug Delivery and Therapeutics 14, no. 3 (March 15, 2024): 147–53. http://dx.doi.org/10.22270/jddt.v14i3.6466.

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Background: Saffron is a significant medicinal herb that has a lot of potential for use in the development of new drugs. Since ancient times, saffron (Crocus sativus L.) has been associated with various health benefits in various parts of the world. Some of these applications have been overlooked over time. However, interest in naturally occurring active compounds has rekindled interest in saffron's past applications and the best applications for saffron today can be aided by knowing its various historical uses. It was prized as a culinary spice as well as a perfume, color, and medicinal herb. It was used medicinally in many different cultures to treat a wide range of ailments, from genitourinary to eye problems. In many countries, it was also used as an antidepressant and tonic substance. Objective: The purpose of this review is to provide an overview of the traditional and modern uses of Crocus sativus, with particular attention to its chemical makeup, pharmacological characteristics, and ethnobotanical description. Methodology: Scientific databases and publications about the chemical profile, biological activity, and historical use of saffron were included in the literature search. Results: Saffron is bitter, acrid, fragrant, stimulant, tonic, stomachic, aphrodisiac, anodyne, antispasmodic, emmenagogue, diuretic, laxative, galactagogue, and helpful in treating bronchitis, vomiting, fever, melancholia, hepatomegaly, etc. it is widely used in alternative medicine, such as the Unani System of Medicine, Ayurveda, and Traditional Chinese Medicine. Saffron has been the subject of numerous phytochemical and biochemical studies due to its extensive use in traditional medical systems. These studies have revealed that saffron contains a number of constituents, including crocetin, safranal, and crocins, the latter of which is primarily responsible for pharmacological actions. Keywords; saffron, medicinal herb, unani medicine, crocetin, safranal, emmenagogue.

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Boontim, S. "EVALUATION OF TOXICITY OF THAI EMMENAGOGUE DRUGS AND THEIR NITROSATED PRODUCTS ON IN VITRO HUMAN LYMPHOCYTES." Acta Horticulturae, no. 679 (February 2005): 21–27. http://dx.doi.org/10.17660/actahortic.2005.679.3.

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Kalam, Mohd Afsahul, Riyaz Ahmad, Mohammad Avid, Abdur Rahim, and Abdul Habib. "Khatmī (Althea officinalis L. and Althea rosea): Medicinal importance in the perspective of Unani medicine and pharmacological studies." Journal of Drug Delivery and Therapeutics 13, no. 12 (December 15, 2023): 270–77. http://dx.doi.org/10.22270/jddt.v13i12.6155.

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Althea officinalis L. is an important Unani Medicinal plant belonging to the family Malvaceae. The herb is commonly known as Khatmī and Marsh-mallow. All parts of the plant such as seeds, leaves, root and flowers are mainly used as medicine in Unani Medicine. It is used for many pharmacological actions like diuretic, lithotriptic, deobstruent, anti-inflammatory, emmenagogue which makes it useful in treatment of kidney stone jaundice, menstrual disorder, hepatitis, headache etc. Many scientific studies are done on the pharmacological actions of this herb. In this chapter both modern and Unani perspective of pharmacological properties of Althea officinalis L. along with its Phytochemistry and pharmacological studies are included. Keywords: Althea officinalis L.; Khatmī; Malvaceae

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Kadam, Rohit. "A Review on Medicinal Properties of Luffa Cylindrica." International Journal for Research in Applied Science and Engineering Technology 12, no. 1 (January 31, 2024): 1535–39. http://dx.doi.org/10.22214/ijraset.2024.58207.

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Abstract: Luffa cylindrica was used for the treatment of, intestinal worms, sinusitis, asthma, chronic bronchitis pain, carbuncles, inflammation, heat rashes of children in summer, bowels or bladder hemorrhage, hemorrhoids, jaundice, haematuria, leprosy, as anti-pyretic, as anthelmintic, carminative, emmenagogue, antioxidant, anti-emetic, galactagogue and as antiseptic immunological, bronchodilating, reproductive effect and in treatment of cataract. The phytochemical screening of Luffa cylindrica disclose that the plant contained anthocyanins, glycosides, flavonoids, triterpenoid, cardiac glycosides, saponins, carbohydrates, proteins, alkaloids, and tannins. The pharmacological investigation showed that Luffa cylindrica possessed, analgesic, antipyretic, hypoglycemic, antibacterial, antifungal, antiviral, anthelmintic, antioxidant, anticancer, hepatoprotective, antiemetic, wound healing, immunological, bronchodilating, reproductive effect and in treatment of cataract. The current review discussed biological effects of Luffa cylindrica

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Javaid, Rasikh, Ghazala Javed, Raheela Javaid, ,. Anju, Farah Ahmed, and Asim Ali Khan. "HING (Ferula foetida Regel): A potent Unani Herb with its descriptive parameters of pharmacognosy and pharmacology: A Review." Journal of Drug Delivery and Therapeutics 10, no. 5 (September 15, 2020): 362–67. http://dx.doi.org/10.22270/jddt.v10i5.4372.

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Hing (Family- Umbelliferae) or asafoetida is the latex obtained from living rootstocks or taproots of several species of Ferula, e.g. F. alliacea Boiss, F. rubricaulis Boiss, F. assafoetida Linn and F. narthex Boiss found in central Asia. Asafoetida occurs in three forms, viz Tears, Mass and Paste. Hing has shown diverse biological and pharmacological activities. It has been used in Unani Medicine (Tibb-e-Unani) and other Traditional Systems of Medicine from time immemorial and it is described as diuretic, anti-diabetic, emmenagogue etc. The present review highlights the botanical description, traditional uses, pharmacognositcal features, pharmacological properties and pharmacological studies conducted on this Medicinal plant used in Unani system of medicine. Keywords: Hing; Ferula foetida; Unani Medicine; Traditional Uses; Pharmacological Properties

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Nezhadali, A., M. Akbarpour, and B. Zarrabi Shirvan. "Chemical Composition of the Essential Oil From the Aerial Parts ofArtemisia Herba." E-Journal of Chemistry 5, no. 3 (2008): 557–61. http://dx.doi.org/10.1155/2008/730453.

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The aerial parts of the plant artemisia herba were collected in the May 2007 from Babaaman (North Khorassan Province of Iran). The plant was isolated by hydro distillation. A total of 61 constituents, representing more than 98% of the oil were identified by gas chromatograph/mass spectrometry (GC/MS). The main compounds, were alpha-pinene (3.28%), champhene (4.8%), sabinen (5.18%), beta-myrcene (3.04), cis,beta-terpineol (11.31%), camphor (6.11%), 8-hydroxylinalool (2.64%), L-4-terpineol ( 2.5%), alpha- therpineol (2.33%), myrtenol (3.27%), bornyl acetate (6.2%), alpha-terpinol acetate (3.06%), germacrene (2.06%), davanone (8.49%), trans-farnesol (4.27%), cis-fernesol (2.07%) and 1,3,dicyclopentyl cyclopentane (2.29%). This herbal medicine traditionally uses as anti-infectious, anti-bacterial, emmenagogue, parasiticide, digestive and stomachic and gastric tonic in Iran.

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Ali Esmail Al-Snafi, Hanaa Salman Khadem, Hussein Ali Al-Saedy, Ali M. Alqahtani, Gaber El-Saber Batiha, and Jafari-Sales Abolfazl. "A review on Medicago sativa: A potential medicinal plant." International Journal of Biological and Pharmaceutical Sciences Archive 1, no. 2 (February 28, 2021): 022–33. http://dx.doi.org/10.30574/ijbpsa.2021.1.2.0302.

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Medicago sativa (Family: Fabaceae) was used traditionally for the treatment of arthritis, kidney problems, fever, as diuretic, anti-cancer, anti-rheumatic, cardiotonic, depurative, lactagogue, emmenagogue, antiscorbutic and in the treatment of boils. Leaves and sprouts were also consumed as vegetable salad. The leaves or seeds were sold as bulk powdered herb, capsules, and tablets for nutritional supplement in health food stores. The phytochemical analysis of Medicago sativashowed the presence of proteins, carbohydrates, saponins, lignin, phenolic compounds, tannins, alkaloids triterpene glycosides, carotenoids, sterols, phytoestrogens, flavones, isoflavonoids and phenolic compounds. The previous pharmacological investigation showed that the plant possessed antioxidant, antidiabetic, reproductive, anti-inflammatory, antimicrobial, dermatological, anxiolytic, hepatoprotective, neuroprotective, immunological, cardioprotective, cytotoxic, anti-scorbutic, anti-anemic, xanthine oxidase inhibition and many other pharmacological effects. The current review discussed the bioactive constituents and pharmacological activities of Medicago sativa.

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Mohd Rais, Nurul Atikah, Norazlina Idris, Shareena Fairuz Abdul Manaf, Hasnizah Habibun, Rafeqah Raslan, Nur Farhana Mat Sahari, Munawar Zaman Shahruddin, and Fazlena Hamzah. "Aspergillus niger ATCC 16404 Producing Pectinase Couple to Polysulfone/Pluronic Membrane Ultrafiltration for Momordica Charantia Juice Clarification." Advanced Materials Research 1113 (July 2015): 177–81. http://dx.doi.org/10.4028/www.scientific.net/amr.1113.177.

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Momordica charantia is an anti-diabetic which is used as carminative, emmenagogue, in the treatment of colics, as antiviral, anthelmintic, antimalarial and antimicrobic remedy. The Momordica charantia was treated with Aspergillus niger pectinase at various concentration (0-500 U/ml), temperature (4-40°C) and times (0-10 min). Aspergillus niger was selected as a promising producer of pectinase via solid state fermentation (SSF) using oil palm leaf (OPL) as substrate because it is abundantly available in Malaysia and rich with carbon source that needed for Aspergillus niger’sgrowth. The optimum treatment conditions were at 30°C, at pH between 6-6.5 at time 10 min with 472.257 U/ml. The enzymatic treatment was followed by ultrafiltration (15kDa). Analysis of the clarified juice indicate that the enzyme permitted a higher permeate flux and high juice quality.

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Navnath, Miss Patil Shivani. "Formulation and Evaluation of Nagarmotha Hair Oil." International Journal for Research in Applied Science and Engineering Technology 9, no. 12 (December 31, 2021): 1107–13. http://dx.doi.org/10.22214/ijraset.2021.39477.

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Abstract: The Presenace study investigation oil isolation form cyperus rotundus and the chemical composition of essential oil of root's of Cyprus rotundus.In india it's commonly known as nagarmotha.and it belongs to the family cyperacea.the major chemical components of this herb are essential oils.flavonoids, terpenoids, sesauiterpenes, cyproten, cyperene, aselinene, rotundene, valencene, cyperol, gurjunene, transcalamenenene, cad'Alene, cyperoutundone, mustskone, isocyperol, acyperone etc. Reserch studies have shown that it possesses various Pharmacological activity Such as diuretic,carmenative emmenagogue, anthelmintic, analgesic, anti-inflammatory, anti-dysentery, anti-rheumatic activities.an extensive review of the ancient traditional literature and madern research revealead that the drug has numerous therapeutic action. Several of which have been established scientifically, which may help the reserchers to set their minds for approaching the utility efficiency and potency of nagarmotha. Keywords: cyperus rotundus, cyprotene flavanoids nagarmotha.

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Fazal, Syed Sufiyan, and Rajeev K Singla. "Review on the Pharmacognostical & Pharmacological Characterization of Apium Graveolens Linn." Indo Global Journal of Pharmaceutical Sciences 02, no. 01 (2012): 36–42. http://dx.doi.org/10.35652/igjps.2012.03.

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Pharmacological properties of medicinal plants and various natural products of plant origin lie in the chemical constituents they contain. Thus, in most cases, the principal aim of phytochemical analysis of plants and natural products is to detect, isolate, characterize and identify these chemical substances. Apium graveolens(Celery plant) is an indigenous plant belongs to family Apiaceae. According to ayurveda, the plant is having a broad spectrum of use as an aphrodisiac, anthelmintic, antispasmodic, carminative, diuretic, emmenagogue, laxative, sedative, stimulant, and toxic. Celery is known as mild diuretic and urinary antiseptic and has been in the relief of flatulence and griping pains. Literature data revealed that A graveolens have many pharmacological properties as antifungal, antihypertensive and hypolipidemic, diuretic, anticancer and many more. Currently review article tried to critically cover all the necessary aspects related of A graveolens.© 2011 IGJPS. All rights reserved.

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Yang, Guochen, Zhongge (Cindy) Lu, and Carl E. Niedziela. "(227) Guava Callus Production In Vitro." HortScience 41, no. 4 (July 2006): 1024D—1024. http://dx.doi.org/10.21273/hortsci.41.4.1024d.

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This research was initiated to study different culture media and plant growth regulators for their influences on callus initiation and production, with a research goal of developing an efficient in vitro callus regeneration protocol for guava (Psidium guajava L.). Guava is an important tropical fruit species that is rich in vitamins and vitamin precursors, minerals, organic acids, and pectins. Seventy-nine phytochemicals provide guava with many unique properties and actions, including anti-microbial, astringent, bactericidal, cicatrizant, emmenagogue, hypoglycemic, laxative, nutritive, and spasmolytic. Different concentrations of various plant growth regulators (PGR), such as 6-benzyladenine (BA), kinetin, or 2,4-dichlorophenoxyacetic acid (2,4-D), and naphthaleneacetic acid (NAA) were added to basic Murashige and Skoog (MS) and woody plant medium (WPM) and tested for their influences. Differences in callus initiation and morphology were noticed between MS and WPM, and among PGR concentration treatments.

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Mohini, Kuchekar, Upadhye Mohini, Kulkarni Amrita, Zambare Aishwarya, Shirke Disha, and Kore Padmaja. "Verbena officinalis (Verbenaceae): Pharmacology, Toxicology and role in female health." International Journal of Ayurvedic Medicine 13, no. 2 (July 8, 2022): 296–304. http://dx.doi.org/10.47552/ijam.v13i2.2748.

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Verbena officinalis Linn (Verbenaceae), the common verbena or vervain, a traditional herb with immense cultural and medicinal significance in the European, Greek, American, Roman and Egyptian countries. Phytochemical analysis suggests the presence of iridoid glycosides, secoiridoid glycosides, phenylethanoid glycosides, flavones, pentacyclic triterpenoids, monoterpenes, sterols and their derivatives. Owing to the presence of these phytochemicals, wide range of pharmacological activities such as antibacterial, antiviral, antifungal, antidiarrheal, antitumour, antidepressant, anxiolytic, gastroprotective and hepatoprotective, etc are reported. Literature survey highlights the distinct role of Verbena officinalis in treating dysmenorrhoea, vaginitis, endometriosis, premenopausal night sweating, herbal tonic for pregnant women and lactating mothers and its use as emmenagogue. The review aims to promote studies on Verbena officinalis for its therapeutic role in female reproductive health and other ailments. The scientific databases used for compilation of the data were Google scholar, Pubmed the data made available specifically from 2010 to 2022.

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Mehraj, Nida, and Mahboob Alam. "Ghafis (Agrimonia eupatoria): An In-depth Review of its Historical Context, Therapeutic properties, Ethnopharmacological applications, and Scientific research." International Journal of Medical Sciences and Pharma Research 10, no. 1 (March 15, 2024): 35–38. http://dx.doi.org/10.22270/ijmspr.v10i1.92.

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Agrimonia eupatoria, commonly known as Ghafis, holds a significant role in traditional herbal medicine across different regions. This perennial plant, part of the Rosaceae family, has been used in Unani medicine for its various healing properties since ancient times. Ghafis is known for its abilities as a demulcent, stomachic, blood purifier, diuretic, emmenagogue, anti-inflammatory, and astringent agent. Traditionally, it has been employed to treat liver and spleen inflammation, fevers, ulcers, jaundice, wounds, and gastrointestinal disorders. Ethnopharmacological practices have also recognized its antioxidant, antimicrobial, and diuretic effects. Recent scientific studies have further explored its potential in managing diabetes, neuropathic pain, oxidative stress-related disorders, and protecting the liver. This review aims to provide an overview of Ghafis, covering its description, habitat, traditional uses, and recent scientific studies. Ghafis emerges as a valuable herbal remedy with ongoing relevance in herbal medicine and Unani pharmacotherapy. Keywords: Ghafis, Agrimonia eupatoria, Agrimony, Unani Medicine

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Hiremath, Shilpa, Pradeep, and Ashwini Jeerankalagi. "Leucas aspera Spreng (Dronapushpi): A Review." Journal of Ayurvedic and Herbal Medicine 8, no. 1 (March 25, 2022): 48–54. http://dx.doi.org/10.31254/jahm.2022.8111.

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Leucas aspera is a plant species belongs to the genus Leucas and the family Lamiaceae. Species has different common names depending its location and most commonly known as Tumbai or Thumba, is distributed throughout India from the Himalayas down to Ceylon. It is known for its various uses in the fields of medicine and agriculture. This article aims to provide a comprehensive review on the pharmacognostic, phytochemical, and pharmacological aspects of Leucas aspera.Traditionally different parts of the plants are used as an antipyretic, insecticide, stimulant, emmenagogue, expectorant, aperient and diaphoretic. Leaves are found to be useful in chronic rheumatism, chronic skin eruptions specially in psoriasis. In case of snake bite, bruised leaves are applied locally. The plant mainly contains triterpenoids, oleanolic acid, b-sitosterol, diterpenes, ursolic acid, nicotine, sterols, glucoside and phenolic compounds. The plant, flower extract and essential oil shows various activities like antioxidant, anti-microbial, anti-fungal and antinociceptive etc.

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Nahar, Lutfun, Hesham R. El-Seedi, Shaden A. M. Khalifa, Majid Mohammadhosseini, and Satyajit D. Sarker. "Ruta Essential Oils: Composition and Bioactivities." Molecules 26, no. 16 (August 6, 2021): 4766. http://dx.doi.org/10.3390/molecules26164766.

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Ruta L. is a typical genus of the citrus family, Rutaceae Juss. and comprises ca. 40 different species, mainly distributed in the Mediterranean region. Ruta species have long been used in traditional medicines as an abortifacient and emmenagogue and for the treatment of lung diseases and microbial infections. The genus Ruta is rich in essential oils, which predominantly contain aliphatic ketones, e.g., 2-undecanone and 2-nonanone, but lack any significant amounts of terpenes. Three Ruta species, Ruta chalepensis L., Ruta graveolens L., and Ruta montana L., have been extensively studied for the composition of their essential oils and several bioactivities, revealing their potential medicinal and agrochemical applications. This review provides a systematic evaluation and critical appraisal of publications available in the literature on the composition and bioactivities of the essential oils obtained from Ruta species and includes a brief outlook of the potential applications of nanotechnology and chitosan-based products of Ruta essential oils.

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Waseem, M., A. Rauf, and S. Rehman. "A SCIENTIFIC REVIEW ON PHYTO-PHARMACOLOGICAL PROPERTIES OF TRIBULUS TERRESTRIS LINN." INDIAN DRUGS 55, no. 10 (October 28, 2018): 7–15. http://dx.doi.org/10.53879/id.55.10.11439.

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Tribulus terrestris Linn. (Zygophyllaceae) has been used since ancient times to treat various health ailments. Different parts of the plant have been used by traditional physicians, however the dried entire fruit is more commonly used as ‘Gokshura’ and ‘Ikshugandha’ in Ayurveda and as ‘Khar-e-Khasak Khurd’ in Unani System of Medicine for its diuretic, aphrodisiac, emmenagogue, laxative, lactagogue, lithotriptic, demulcent, stomachic and astringent properties. It is therapeutically employed for its efficacy in vesicular calculi, urinary discharge, strangury, sexual debility, dysuria, burning micturation, ammenorrhoea, cough and asthma. Fruits contain traces of alkaloids, flavonoids, fixed oil, small quantity of essential oil, resins and nitrates. This review aims to provide an electronic database regarding phytopharmacological properties of T. terrestris, in particular with its description in Unani classical literature along with the recent research work done by many authors; so that future research work can be made at ease and it will help in revalidating scientifically the claimed activities of the drug mentioned in classical literatures and further exploration of any new therapeutic activity based on phyto-chemistry.

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Sultana, Arshiya, Syed Lamatunoor, Mazherunnisa Begum, and Q. N. Qhuddsia. "Management of Usr-i-Tamth (Menstrual Pain) in Unani (Greco-Islamic) Medicine." Journal of Evidence-Based Complementary & Alternative Medicine 22, no. 2 (July 7, 2016): 284–93. http://dx.doi.org/10.1177/2156587215623637.

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Usr-i-tamth in Unani (Greco-Arabic) medicine is pain associated with menstruation, and classical manuscripts are enriched with traditional knowledge for the management of usr-i-tamth (menstrual pain/dysmenorrhoea). Hence, a comprehensive search was undertaken to find classical manuscripts for the management of menstrual pain was. We searched the Cochrane database, PubMed/Google Scholar, and other websites for articles on complementary and alternative medicine treatment and management of menstrual pain. The principal management as per Unani manuscripts is to produce analgesia and to treat the cause of usr-i-tamth such as abnormal temperament, menstrual irregularities/uterine diseases, and psychological and environmental factors. Furthermore, Unani medicines with emmenagogue, antispasmodic, anti-inflammatory, and analgesic properties are beneficial for amelioration of usr-i-tamth. Herbs such as Apium graveolens, Cuminum cyminium, Foeniculum vulgare, Matricaria chamomilla and Nigella sativa possess the aforementioned properties and are proven scientifically for their efficacy in usr-i-tamth. Thus, validation and conservation of the traditional knowledge is essential for prospective research and valuable for use in the contemporary era.

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Martins, Elton A. S., André L. D. Goneli, Claúdia A. L. Cardoso, Gabriela L. de Almeida, Alexandre A. Gonçalves, and Cristiane B. da Silva. "Post-harvesting of Solanum paniculatum L. leaves. Part II: Antioxidant activity and chemical composition." Revista Brasileira de Engenharia Agrícola e Ambiental 25, no. 1 (January 2021): 17–22. http://dx.doi.org/10.1590/1807-1929/agriambi.v25n1p17-22.

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ABSTRACT ‘Jurubeba’ (Solanum paniculatum L.) is a medicinal plant used in traditional medicine for liver problems, in addition to being used as a cholagogue, emmenagogue, healing agent, febrifuge, anti-inflammatory, antipyretic, tonic, decongestant, diuretic and against inappetence. Thus, the objective of this study was to evaluate the antioxidant activity, concentration of phenolic compounds and total alkaloids of aqueous extracts prepared from ‘Jurubeba’ leaves subjected to drying. ‘Jurubeba’ leaves were dried at different temperatures (40, 50, 60 and 70 °C) and velocities (0.4 and 0.8 m s-1) of the drying air. Aqueous extracts of the leaves, subjected to drying, were evaluated by absorbance reading in a spectrophotometer. Increase in drying air temperature reduced the contents of total phenolics and total alkaloids of the leaf aqueous extracts, whereas increment in air velocity increased the concentration of these substances. Antioxidant activity was not influenced by the increase in air temperature at air velocity of 0.4 m s-1, but under air velocity of 0.8 m s-1 there was reduction with increasing temperature. Drying of ‘Jurubeba’ leaves can be carried out with temperature of 40 or 50 °C and drying air velocity of 0.4 m s-1.

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Anju, ,., Ghazala Javed, Rasikh Javaid, and Farah Ahmed. "Kasni (Cichorium intybus): A Unani Hepatoprotective Drug." Journal of Drug Delivery and Therapeutics 10, no. 4 (July 15, 2020): 238–41. http://dx.doi.org/10.22270/jddt.v10i4.4162.

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Kasni (Cichorium intybus Linn.) is a powerful hepatoprotective and nephroprotective drug which has been extensively used in Unani System of Medicine. It is commonly known as chicory in English language. It is an erect perennial herb of the dandelion family Asteraceae. There are two types of Kasni depending on colour of the flowers which are usually bright blue and white or pink rarely. Chicory consists of a dietary fibre called as Inulin which is very useful in treating diabetes and constipation. As per Unani classical literature, it has been extensively used as Mufatteh Sudud (Deobstruent), Musaffi Dam (Blood Purifier), Muqawwi Kabid (Hepatic Tonic), Muqaiwwi Meda (Tonic for Stomach), Waram e Meda (Gastritis), Amraz e Kabid (Liver Disorders), Ghisyan (Nausea and Vomiting), Amraze Kulliya (Kidney Diseases), etc. The root of Kasni possesses various properties such as Aperient, Cholagogue, Deobstruent, Diuretic, Emmenagogue, Febrifuge, Resolvent. Its leaves’ decoction is used as lithotriptic and also useful in elimination of internal mucus. This paper gives an overview of types, phytochemical studies, pharmacological actions and therapeutic uses of Kasni as per Unani classical literature and current scientific studies. Keywords: Kasni, Cichorium intybus Linn., Unani System of Medicine, Hepatoprotective, Unani drug.

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Gantait, Arunava, Subrata Pandit, Neelesh K. Nema, and Pulok K. Mukjerjee. "Quantification of Glycyrrhizin in Glycyrrhiza Glabra Extract by Validated HPTLC Densitometry." Journal of AOAC INTERNATIONAL 93, no. 2 (April 1, 2010): 492–95. http://dx.doi.org/10.1093/jaoac/93.2.492.

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Abstract Glycyrrhiza Glabra Linn (Family-Fabaceae) is active as an anti-allergic, anti-inflammatory, spasmolytic, mild laxative, antistress, antidepressive, antiulcer, liver protective, estrogenic, emmenagogue, and antidiabetic substance, and is widely used in the Indian system of medicine. The major bioactive constituent is glycyrrhizin. A simple HPTLC method has been developed to control the quality of raw as well as finished glycyrrhiza using glycyrrhizin as the bioactive marker. The solvent system was optimized to chloroformmethanolwater (65 + 36 + 7.5, v/v/v). Extract and standard were dissolved in 70 methanol and applied on a precoated TLC plate. After development, the plate was scanned at 254 nm to create a chromatogram, then the quantity of glycyrrhizin was determined in the extract. The method was validated in terms of specificity, linearity, precision, LOD, and LOQ. Linearity range was found to be 0.964.80 g per spot. The linearity relationship was described by the equation: Y 612.706 + 1.091X (with r 0.99904 and SD 2.52), where Y is the area under curve and X is the amount of glycyrrhizin (ng). The amount of glycyrrhizin found in the extract was 9.1. Thus, the method provides a rapid and cost-effective quality measure for Glycyrrhiza Glabra hydroalcoholic extract.

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Ruis, A. R. "Pomegranate and the Mediation of Balance in Early Medicine." Gastronomica 15, no. 1 (2015): 22–33. http://dx.doi.org/10.1525/gfc.2015.15.1.22.

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Different elements of the pomegranate, both tree and fruit, had a wide range of uses in premodern therapeutics. Pomegranate also had a rich symbolic role in the art, literature, and religion of numerous cultures. In nearly every part of the globe where the pomegranate grew, it came to represent fundamental dualities: life and death, inside and out, many and one. The medicinal purposes for which healers recommended pomegranate at times reflected broader symbolic associations, and those associations are an important part of the therapeutic tradition. The dualistic symbolism that attended the pomegranate in various cultural traditions synergized with dualistic medical concepts, reinforcing the therapeutic power of pomegranate in otherwise diverse contexts. Reflecting this duality, pomegranate was both an astringent and a laxative, an emmenagogue and an antimenorrhagic, an expectorant and an antiemetic, a pyrogen and a febrifuge, a restorative and a soporific. In both literary and medical traditions, the pomegranate mediated transitions—or maintained balance—between opposing states. This essay provides an overview of the rich and sundry uses of pomegranate in premodern therapeutics, revealing how cultural associations both reflected and informed medical practices.

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Rosa, D., B. Elya, M. Hanafi, and A. Khatib. "In vitro and molecular docking of α-Glucosidase inhibitor potency from Artabotrys suaveolens leaf and stem bark." IOP Conference Series: Earth and Environmental Science 1116, no. 1 (December 1, 2022): 012007. http://dx.doi.org/10.1088/1755-1315/1116/1/012007.

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Abstract Artabotrys suaveolens is one of the species from Artabotrys genus, one of the largest genus from Annonaceae family. This plant has been used traditionally to treat several diseases and also as emmenagogue. This research was aimed to explore the potency of Artabotrys suaveolens`s leaf and stem bark extracts as α-glucosidase inhibitor using in vitro and molecular docking techniques. It was found that IC50 of α-glucosidase inhibition activity of leaf extract was 48.18±0.16 ppm while the one of stem bark extract was 44.99±0.35 ppm. Besides that, it was also found that IC50 of DPPH free radical scavenging activity of leaf extract was 114.074 ppm and of stem bark extract was 63.640 ppm. Further analysis indicated that α-glucosidase inhibition activity had stronger relationship with antioxidant activity in leaf extract compared to that in stem bark extract. Using LC-MS/MS, 23 compound structures were identified from leaf and stem bark extracts which were then analyzed using simulations of molecular docking to α-glucosidase receptor. The molecular docking results showed that several compounds both from leaf and stem bark extracts had good affinities to α-glucosidase receptor.

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Sirisa-Ard, Panee, Kiatisak Pholsonklam, Dinh Thi Xuyen, Dinh Thi Dieu Hang, Vu Dinh Chinh, Lê Thiên Kim, Zito Viegas, Da Cruz, Pacharamon Sorncharoen, and Choosak Nithikathkul. "Chemical Composition, Antibacterial and Antioxidant Activities of Extracts from Dry Leaves and Ash-Dry Leaves of Luffa cylindrica (L.) Roem Cultivated in Vietnam." Asian Journal of Research in Medical and Pharmaceutical Sciences 12, no. 4 (September 15, 2023): 38–51. http://dx.doi.org/10.9734/ajrimps/2023/v12i4230.

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Luffa cylindrica (L.) Roem was traditionally used to treat stomachaches, as antihyperlipidemic and antioxidant, particularly for atherosclerosis therapy, as a suppository to cure constipation and spleenopathy, as an anthelmintic, carminative, emmenagogue, galactagogue, and as an antiseptic. Therefore, the aim of this study was to study the chemical composition, antibacterial and antioxidant properties of an extract from dry leaves (LuL) compared to ash-dry leaves (LuA) of Luffa cylindrica (L.) Roem. Our results showed the physical-chemical and phytochemical properties, antioxidant activity, antibacterial activity and the metal ion content of both extracts. The comparison between the extract from dry leaves (LuL) and ash-dry leaves (LuA) of Luffa cylindrica (L.) Roem, showed difference in quantitative phytochemical determination of cardiac glycosides, alkaloids, phenolics, flavonoids, and triterpenoids. This finding may be related to the LuA sample being burned out incompletely into ash. Furthermore, this study showed that the activity of extracts from dry leaves (LuL) and ash-dry leaves (LuA) contained both bacteriostatic and bactericidal effects. The antioxidant properties observed may be related to , the flavonoids content. The presence of metal ions in both extracts, which may contribute to the known wound healing effects, deserves further study.

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Subaş, Tuğba, Ufuk Özgen, İçim Gökkaya, and Gülin Renda. "PETROSELINUM CRISPUM (MILL.) FUSS (PARSLEY), A FOOD AND MEDICINALLY IMPORTANT PLANT: A REVIEW OF RECENT STUDIES BETWEEN 2013-2023." Ankara Universitesi Eczacilik Fakultesi Dergisi 48, no. 2 (April 8, 2024): 7. http://dx.doi.org/10.33483/jfpau.1362626.

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Objective: Petroselinum crispum (Mill.) Fuss is a bright green biennial medicinal and aromatic herb that grows almost all over the world. Today, it is one of the most commonly used culinary herbs. In addition to its use as food, it has been shown to possess broad pharmacological activities in several in vivo and in vitro studies. This study aimed to comprehensively summarize the current studies on the traditional use, phytochemical composition, pharmacological activities, clinical studies, toxicity, and drug interactions of parsley. Result and Discussion: According to the literature data, parsley is used as a diuretic, carminative, emmenagogue and for the prevention and treatment of kidney stone formation, the treatment of conditions such as urinary tract infections and stomach disorders. Its phytochemical composition consists of flavonoids, coumarins, phenolic compounds, organic acids, carotenoids, vitamins, minerals, fixed oil, essential oil, and other compounds. Studies on P. crispum have shown that it has a wide range of pharmacological activities, including antioxidant, antibacterial, antifungal, antidiabetic, antihypertensive, antiplatelet, analgesic, antiinflammatory, antihepatotoxic, antinephrotoxic, anticancer, antiurolithiatic, wound healing, antiobesity, estrogenic and neuroprotective effects. This review comprehensively summarizes the scientific data of the last ten years (2013-2023) on P. crispum.

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Eliaser, Enas Mohamed, Jun Hui Ho, Najihah Mohd Hashim, Yaya Rukayadi, Gwendoline Cheng Lian Ee, and Ahmad Faizal Abdull Razis. "Phytochemical Constituents and Biological Activities of Melicope lunu-ankenda." Molecules 23, no. 10 (October 20, 2018): 2708. http://dx.doi.org/10.3390/molecules23102708.

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Natural products, either pure compounds or standardized plant extracts, have provided opportunities for the discovery of new drugs. Nowadays, most of the world’s population still relies on traditional medicines for healthcare purposes. Plants, in particular, are always used as traditional medicine, as they contain a diverse number of phytochemicals that can be used for the treatment of diseases. The multicomponent feature in the plants is considered a positive phytotherapeutic hallmark. Hence, ethnopharmacognosy has been the focus for finding alternative treatments for diseases. Melicope lunu-ankenda, also known as Euodia lunu-ankenda, is widely distributed in tropical regions of Asia. Different parts of M. lunu-ankenda have been used for treatment of hypertension, menstrual disorder, diabetes, and fever, and as an emmenagogue and tonic. It has also been consumed as salad and as a condiment for food flavorings. The justification of use of M. lunu-ankenda in folk medicines is supported by its reported biological activities, including its cytotoxic, antibacterial, antioxidant, analgesic, antidiabetic, and anti-inflammatory activities. This review summarizes the phytochemical compounds isolated from various parts of M. lunu-ankenda, such as root and leaves, and also its biological activities, which could make the species a new therapeutic agent for some diseases, including diabetes, in the future.

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Papakosta, Konstantina, Maria-Eleni Grafakou, Christina Barda, Ioannis V. Kostopoulos, Ourania Tsitsilonis, and Helen Skaltsa. "Cytotoxicity and Anti-cancer Activity of the Genus Achillea L." Current Medicinal Chemistry 27, no. 41 (December 8, 2020): 6910–25. http://dx.doi.org/10.2174/0929867327666200505092514.

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Background: The genus Achillea L. is rich in bioactive sesquiterpenes and flavonoids; most of the studied species exhibit several biological activities and are used as emmenagogue, wound healing and analgesic agents. Some species are also used in local folklore medicine. Objective: Following a literature survey, we discuss the anti-cancer properties of Achillea species, taking into consideration ethnopharmacological data on their use in traditional medicine for the treatment of cancer. In addition, we screened extracts and isolated secondary metabolites from A. coarctata for cytotoxicity, upon information based on local traditional medicine. The plant was collected in Kozani (Northern Greece), where it is locally used for treating gastrointestinal disorders, including stomach cancer. Methods: A selection of the relevant data was performed through a search in PubMed, Scopus, Google Scholar and Science Direct databases. In addition, extracts and isolated compounds from A. coarctata were tested for their in vitro activity against the human cancer cell lines MCF-7 and HeLa. Conclusion: The genus Achillea L. is a valuable source of bioactive secondary metabolites. The most significant outcome of the investigation of medicinal plants is the documentation and the assessment of the traditional information and its use and perspectives in the light of modern pharmacology.

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Karunanithi, Shalini, Vijaya Bharathi Rajkishore, Vandhana Ganesh Pol, Sitharathul Mumthana M. Mumthana. M, D. Abirami, and Jayshree. "Pharmacognostical and phytochemical studies on leaves of Oxalis corniculata Linn." Journal of Phytopharmacology 5, no. 6 (December 24, 2016): 225–29. http://dx.doi.org/10.31254/phyto.2016.5603.

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Oxalis corniculata Linn is an annual herb commonly known as Indian horrel belonging to the family Oxalidaceae. It is found to uses as, anthelminitic, astringent, diuretic, emmenagogue, febrifuge, cardiac disorders, diarrheoa, dysmenorrhoea, hepatic disorders, eye disease, scurvy and toxicity. This research work deals with the Pharmacognostical and Phytochemical studies on leaves of Oxalis corniculata Linn microscopic photographs of transverse section (T.S) of Oxalis corniculata should distinct presentation of epidermal trichomes, calcium oxalate crystals and stomata. Standardization of the plant were done with the help of extractive values [ alcohol soluble extractive (16%w/w), water soluble extractive (24%w/w)], total ash (15%w/w), acid insoluble ash (1.7%w/w), water soluble ash (1.8%w/w), sulphated ash (0.9%w/w). Pytochemical analysis showed the presence of carbohydrates, glycosides, flavanoids, phenols, tannins, volatile oils, aminoacids and proteins. The dried coarsely powdered Oxalis corniculata plant was extracted with ethanol 600C in soxhlet apparatus for 24 hours. Another extract is prepared in cold maceration method for 7 days using water. The both extract was collected and preserved in a vaccum desicator. Fluorescence analysis was carried out for the plant powder and extract. This study various Pharmacognostical and physiochemical parameters for the identification and standardization of the plant material and Phytochemical screening for determination of active constituents.

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Costa, Kassiane Cristine da Silva, Suzana Barbosa Bezerra, Clevanice Moreira Norte, Luciana Macatrão Nogueira Nunes, and Tiago Moreira de Olinda. "Medicinal plants with teratogenic potential: current considerations." Brazilian Journal of Pharmaceutical Sciences 48, no. 3 (September 2012): 427–33. http://dx.doi.org/10.1590/s1984-82502012000300009.

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The aim of this study was to present the implications of the use of herbs during pregnancy, pointing out those that should be avoided during this condition because of their abortifacient and/or teratogenic potential. We carried out searches in the databases ScienceDirect, Scielo and Google Scholar, adopting as criteria for inclusion: book chapters and/or complete articles (with abstract), available in English, Portuguese or Spanish, published from 1996 to in 2011. After a pre-selection of 83 articles, 49 bibliographies were used in the manufacturing end of the article, where 25 were from the Scielo database, 18 from ScienceDirect and 6 from Google Scholar. From the articles studied, we identified the four most commonly used plants as emmenagogue/abortifacient agents by patients of the Department of Prenatal SUS: senne, arruda, boldo and buchinha-do-norte or cabacinha. Thus, we conclude that people often adhere to the maxim "if it's natural, it does no harm" in their rational use of natural products, without the right guidance, believing that these products are safe to use. This usage is even more worrisome among the elderly, pregnant women and children. Regarding the safety of these products, some information and reliable data are scarce or contradictory.

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Kuhn, Andrielle Wouters, Marília Tedesco, Aline Augusti Boligon, Viviane Dal-Souto Frescura, Margareth Linde Athayde, and Solange Bosio Tedesco. "Genotoxic and chromatographic analyses of aqueous extracts of Peltodon longipes Kunth ex Benth. (hortelã-do-campo)." Brazilian Journal of Pharmaceutical Sciences 51, no. 3 (September 2015): 533–40. http://dx.doi.org/10.1590/s1984-82502015000300005.

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Peltodon longipes is used as a stimulant and emmenagogue. The objective of this study was to perform genotoxic and chromatographic analyses of the extracts of two samples of P. longipes, collected from the cities of Santa Maria and Tupanciretã, RS, Brazil. The Allium cepa assay was used to analyze genotoxicity while high-performance liquid chromatography was employed to determine phenolic compounds. The genotoxicity experiment consisted of nine groups each comprising four A. cepa bulbs. Bulb roots were developed in distilled water and then transferred for the treatments, for 24 hours, and the negative control remained in water. The treatments were: aqueous extracts at concentrations of 5 and 15 g L-1 for each sample, plus four groups treated with 1% glyphosate, one of which was used as a positive control and the other three for testing DNA damage recovery using water and the extracts of P. longipes from Santa Maria. All extracts of P. longipes exhibited anti-proliferative potential, although the effect was significantly greater for the extracts from the Tupanciretã sample. This sample also contained the highest amount of rosmarinic acid and kaempferol, which may confer the effects found in these extracts. Only extracts from the Santa Maria sample exhibited genotoxic potential.

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Li, Cai-Wei, Yi-Cheng Chu, Chun-Yi Huang, Shu-Ling Fu, and Jih-Jung Chen. "Evaluation of Antioxidant and Anti-α-glucosidase Activities of Various Solvent Extracts and Major Bioactive Components from the Seeds of Myristica fragrans." Molecules 25, no. 21 (November 8, 2020): 5198. http://dx.doi.org/10.3390/molecules25215198.

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Myristica fragrans is a well-known species for flavoring many food products and for formulation of perfume and medicated balm. It is also used to treat indigestion, stomach ulcers, liver disorders, and, as emmenagogue, diaphoretic, diuretic, nervine, and aphrodisiac. We examined antioxidant properties and bioactive compounds in various solvent extracts from the seeds of M. fragrans. Methanol, ethanol, and acetone extracts exhibited relatively strong antioxidant activities by 2,2-diphenyl-1-(2,4,6-trinitrophenyl)hydrazyl (DPPH), 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), superoxide radical, and hydroxyl radical scavenging tests. Furthermore, methanol extracts also displayed significant anti-α-glucosidase activity. Examined and compared to the various solvent extracts for their chemical compositions using HPLC analysis, we isolated the ten higher content compounds and analyzed antioxidant and anti-α-glucosidase activities. Among the isolates, dehydrodiisoeugenol, malabaricone B and malabaricone C were main antioxidant components in seeds of M. fragrans. Malabaricone C exhibited stronger antioxidant capacities than others based on lower half inhibitory concentration (IC50) values in DPPH and ABTS radical scavenging assays, and it also showed significant inhibition of α-glucosidase. These results shown that methanol was found to be the most efficient solvent for extracting the active components from the seeds of M. fragrans, and this material is a potential good source of natural antioxidant and α-glucosidase inhibitor.

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Kale, Balasaheb, Abhijeet Suresh Bambare, and Mangesh Shankar Bhale. "Anatomical study of Glossocardia bosvallia (L.f.) DC. (Asteraceae)." South Asian Journal of Experimental Biology 13, no. 3 (June 22, 2023): 205–12. http://dx.doi.org/10.38150/sajeb.13(3).p205-212.

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The investigated medicinally and ethno-medicinally very important taxon endemic to the Western Ghats of India. This taxon belonging to the medicinally rich sources of Asteraceae plant family. The various medicinally important components deposited in various parts of plant. The current investigation was completed to find the anatomical characters of Glossocardia bosvallia. The G. bosvalliaan endemic taxa to India, were a major plant population distributed in the Western Ghats of India.The plant shows distinct anatomical characters of stem and root. It shows the presence of resin oil cavities and large solitary calcium crystals in the region of the cortex of the stem and root of G. bosvallia. During the study of G. bosvalliawe noted different anatomical attributes transverse section of the stem and root, were as epidermis layer, cortex, sclereids, cork, vascular bundle, phloem cell layer, phloem medullary rays, xylem medullary rays, xylem vessels, arc vascular bundle, and pitted type parenchyma. This taxon's anatomical study has yet to be studied by a single researcher. The various plant parts have some medicinally important depositions that will be used in the future to cure diseases or abnormalities. G. bosvallia species has a prominent ethnomedicinal plant used for treatments of various illnesses and irregularities such as throat infection, hoarseness of throat, alcohol addiction, anti-fertility action, and bacillary dysentery, anthelmintic, cure bloat, swelling, pains, sores, wounds, emmenagogue, and gynecological disorders.

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Burri, Josef, and Bernhard Uehleke. "Caesalpinia sappan – Sappanholz, Fahng." Zeitschrift für Phytotherapie 40, no. 05 (November 2019): 213–14. http://dx.doi.org/10.1055/a-0899-6156.

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Caesalpinia sappan (L.) oder Sappanholz gehört zur Familie der Fabaceae (Hülsenfrüchtler). Der bis zu 8 m hohe Strauch oder Baum mit leuchtend gelben, rispenartigen Blüten liefert ein Holz, das in südostasiatischen Medizinsystemen (Thailand, Philippinen und andere Länder) sowie im Ayurveda für gesundheitsfördernde und therapeutische Zwecke Verwendung findet. Dabei stehen drei Einsatzgebiete im Vordergrund: Das Sappanholz soll als eine Art von Bluttonikum wirken, allerdings weniger im Sinne von Blutbildung (das würde sinnbildlich wegen der rötlichen Farbe naheliegen), sondern gemäß der traditionellen thailändischen Medizin für Menschen mit „heißem Blut“ oder dem Element Feuer. Daraus leitet sich ein zweites Einsatzgebiet ab: Der aus Sappanholz hergestellte „Tee“ löscht den Durst und mindert die „innere Hitze“. Drittens soll das Sappanholz bei einer Störung der Elemente Feuer, Wasser und Wind hilfreich sein, vor allem bei Asthma oder bei erschwertem Atmen (beispielsweise bei hartnäckiger Bronchitis). Dabei könnten auch entzündungshemmende Eigenschaften eine Rolle spielen. Empfohlen wird das Sappanholz, um die Monatsblutung anzuregen (natürlich nicht bei Schwangerschaft); wahrscheinlich hängt diese Verwendung als Emmenagogum mit dem ersten Einsatzgebiet als Bluttonikum zusammen. Vermutet wird ferner eine ausgleichende Wirkung auf den Blutzuckerspiegel.

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Nandhini, Sundaresan, Kasthuri Bai Narayanan, and Kaliappan Ilango. "VALERIANA OFFICINALIS: A REVIEW OF ITS TRADITIONAL USES, PHYTOCHEMISTRY AND PHARMACOLOGY." Asian Journal of Pharmaceutical and Clinical Research 11, no. 1 (January 1, 2018): 36. http://dx.doi.org/10.22159/ajpcr.2017.v11i1.22588.

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Valeriana is a well-known Indian traditional medicinal herb with sleep remedy. It has been used over the years to treat nervine and sedative in hysteria, epilepsy, and sedative in nervous anxiety. It has also been used as an aromatic stimulant and reported some distinctive indications, as well as its use for rheumatism, low-grade fevers, and aphrodisiac. It has been known to grow well in regions of Europe, parts of Asia and North America. This systematic review focuses on the ethnopharmacological uses of Valeriana, including recent advances on the phytochemical and pharmacological study of Valeriana officinalis. In addition, future developments and scenarios in the study of the plant have been proposed. Various literature and electronic databases such as PubMed, ScienceDirect, Springer, and Wiley were searched and data obtained. Other online academic libraries such as Google Scholar and ethnopharmacological literature were searched systematically for more information on the plant. In this paper, we have reviewed various research conducted on V. officinalis especially in areas of its ethnopharmacological use, phytochemicals, and pharmacology. This plant has been used medicinally for a minimum of 2000 years. It is used in the treatment of brain disorder and also used for the treatment of varied nervous disorders, antispasmodic, anthelmintic, diuretic, diaphoretic, and emmenagogue, and hysteria. More research is needed in the area of pharmacokinetics and toxicology to give further information on the clinical use and control the quality of the plant.

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Nandhini, Sundaresan, Kasthuri Bai Narayanan, and Kaliappan Ilango. "VALERIANA OFFICINALIS: A REVIEW OF ITS TRADITIONAL USES, PHYTOCHEMISTRY AND PHARMACOLOGY." Asian Journal of Pharmaceutical and Clinical Research 11, no. 1 (January 1, 2018): 36. http://dx.doi.org/10.22159/ajpcr.2018.v11i1.22588.

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Valeriana is a well-known Indian traditional medicinal herb with sleep remedy. It has been used over the years to treat nervine and sedative in hysteria, epilepsy, and sedative in nervous anxiety. It has also been used as an aromatic stimulant and reported some distinctive indications, as well as its use for rheumatism, low-grade fevers, and aphrodisiac. It has been known to grow well in regions of Europe, parts of Asia and North America. This systematic review focuses on the ethnopharmacological uses of Valeriana, including recent advances on the phytochemical and pharmacological study of Valeriana officinalis. In addition, future developments and scenarios in the study of the plant have been proposed. Various literature and electronic databases such as PubMed, ScienceDirect, Springer, and Wiley were searched and data obtained. Other online academic libraries such as Google Scholar and ethnopharmacological literature were searched systematically for more information on the plant. In this paper, we have reviewed various research conducted on V. officinalis especially in areas of its ethnopharmacological use, phytochemicals, and pharmacology. This plant has been used medicinally for a minimum of 2000 years. It is used in the treatment of brain disorder and also used for the treatment of varied nervous disorders, antispasmodic, anthelmintic, diuretic, diaphoretic, and emmenagogue, and hysteria. More research is needed in the area of pharmacokinetics and toxicology to give further information on the clinical use and control the quality of the plant.

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Saha, Piyali, Ghungroo Saraswat, Pratip Chakraborty, Sayani Banerjee, Bikas C. Pal, and Syed N. Kabir. "Puerarin, a selective oestrogen receptor modulator, disrupts pregnancy in rats at pre-implantation stage." REPRODUCTION 144, no. 5 (November 2012): 633–45. http://dx.doi.org/10.1530/rep-11-0423.

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The tubers ofPueraria tuberosahave folkloric repute as emmenagogue. The n-BuOH fraction of the ethanolic extract of tubers exhibits significant antifertility activity in laboratory animals. The present investigation explored the active principle(s) of the tuber extract with reference to contragestive effects in rats and probed the possible mechanism of action. Bioactivity-guided fractionation identified puerarin as the major constituent that exerted pregnancy-terminating effects. Oral administration of puerarin at ≥300 mg/kg per day for days (D) 1–2 post-coitus resulted in complete implantation failure. Serum oestradiol levels during D2–D5 and progesterone (P4) level on D5 remained unaffected, but the endometrial expression of oestrogen receptor α (ERα) and ERβ was adversely modulated that disrupted the implantation-specific characteristic endometrial oestrogenic milieu. The eventual consequence was loss of endometrial receptivity characterised by down-regulation of the uterine expression of P4receptor (PR) and attenuation of endometrial expression of leukaemia inhibitory factor, vascular endothelial growth factor and cyclo-oxygenase-2, the three important signalling molecules involved in the process of implantation. Light microscopic examination of the embryos demonstrated no untoward effect of puerarin on the development of embryos until D4, but D5 blastocysts underwent gross morphological distortion. The findings taken together are interpreted to suggest that puerarin adversely impacts the uterine expression of ER and PR that disrupts the implantation-conducive uterine milieu and prevents implantation. In conclusion, puerarin may be envisaged as a prospective molecule that merits further exploration for the development of non-steroidal post-coital contraceptive for women.

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Ansari, Shamim, Wajeeha Begum, and Haqeeq Ahmad. "Review Article Trigonella foenum graecum (Methi): An important botanical drug of Unani system of medicine for the management of gynecological disorders." Journal of Drug Delivery and Therapeutics 11, no. 2-S (April 15, 2021): 167–74. http://dx.doi.org/10.22270/jddt.v11i2-s.4805.

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Hulbah (methi) is a botanical drug used in traditional system of medicine and claimed to be effective in the management of gynecological disorders. In this study the aim is to review the role of Hulbah in the management of gynecological disorders (like Warm-e-Rahim, Warm-e-Unq-ur-Rahim, Cervicitis, galactogouge, dysmenorrhea uterine tonic, emmenagogue, labour pain, Mudirr-e-boul, Mudirr-e-Haiz, Mushile Wilaadat, Salabat Rehm, Warm-e-Rehm, Quruhal Rahim) as mentioned in Unani literature. A review of literature on Hulbah was undertaken using the bibliographic database viz. Pub Med, Google Scholar, Science Direct and Scopus. The search was conducted using the terms ‘Hulbah’, ‘Methi’, ‘Trigonella foenum-gracum’, ‘Fenugreek ’and ‘Hu Lu Ba’. Further, books published in Urdu and English were used to compile the information as representative literature in Unani medicine. The result of review enumerated that Hulbah as such and as an ingredient in various formulations has been used for the management of gynecological disorders since ancient times mainly by the practitioners of traditional medicines. Literature of Unani medicine clearly indicated that Hulbah and its different formulations are safe in gynecological disorders. Sufficient information in respect of Antiarthritic effect, Antibacterial and Antifungal activity, Hypolipidemic effect, Anthelmintic activity, Estrogenic activities, Effect on polycystic ovarian syndrome, Anti-inflammatory and analgesic activities etc., of Hulbah are available. Hulbah and its formulations have been claimed by Unani medicine to be useful in the management of gynecological disorders. Modern scientific reports though scarce, also suggest the possibility of such an effect. Keywords: Methi: Hulbah: Trigonella foenum gracium: Fenugreek

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Laura Silva, Fernandes, da Costa Ygor Ferreira Garcia, de Bessa Martha Eunice, Ferreira Adriana Lucia Pires, do Amaral Corrêa José Otávio, Del-Vechio Vieira Glauciemar, de Sousa Orlando Vieira, Santos de Matos Araújo Ana Lúcia, Castilho Paula C, and Alves Maria Silvana. "Metabolic profiling and antibacterial activity of Eryngium pristis Cham. & Schltdl. - prospecting for its use in the treatment of bacterial infections." Archives of Pharmacy and Pharmaceutical Sciences 5, no. 1 (November 3, 2021): 020–28. http://dx.doi.org/10.29328/journal.apps.1001027.

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Morbidity and mortality of the infected patients by multidrug-resistant bacteria have increased, emphasizing the urgency of fight for the discovery of new innovative antibiotics. In this sense, natural products emerge as valuable sources of bioactive compounds. Among the biodiversity, Eryngium pristis Cham. & Schltdl. (Apiaceae Lindl.) is traditionally used to treat thrush and ulcers of throat and mouth, as diuretic and emmenagogue, but scarcely known as an antimicrobial agent. With this context in mind, the goals of this study were to investigate the metabolic profile and the antibacterial activity of ethanolic extract (EE-Ep) and hexane (HF-Ep), dichloromethane (DF-Ep), ethyl acetate (EAF-Ep) and butanol (BF-Ep) fractions from E. pristis leaves. Gas Chromatography-Mass Spectrometry (GC-MS) was performed to stablish the metabolic profile and revealed the presence of 12 and 14 compounds in EAF-Ep and HF-Ep, respectively. β-selinene, spathulenol, globulol, 2-methoxy-4-vinylphenol, α-amyrin, β-amyrin, and lupeol derivative were some of phytochemicals identified. The antibacterial activity was determined by Minimal Inhibitory Concentration (MIC) using the broth micro-dilution against eight ATCC® and five methicillin-resistant Staphylococcus aureus (MRSA) clinical strains. HF-Ep was the most effective (MIC ≤ 5,000 µg/µL), being active against the largest part of tested Gram-positive and Gram-negative bacterial strains, including MRSA, with exception of Escherichia coli (ATCC 25922) and Pseudomonas aeruginosa (ATCC 9027) and (ATCC 27853). These results suggest that E. pristis is a natural source of bioactive compounds for the search of new antibiotics which can be an interesting therapeutic approach to recover patients mainly infected by MRSA strains.

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Guariniello, Julián, Jésica Iannicelli, Patricia Angélica Peralta, and Alejandro Salvio Escandón. "In vivo and in vitro propagation of “macela”: a medicinal-aromatic native plant with ornamental potential." Ornamental Horticulture 24, no. 4 (October 30, 2018): 361–70. http://dx.doi.org/10.14295/oh.v24i4.1238.

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Achyrocline satureioides is a shrub native from South America. In popular medicine it is used in infusions such as digestive, carminative, antispasmodic, eupeptic and emmenagogue. However, its main use is as an ingredient in the liquor industry. Commercial exploitation is carried out through the collection of natural populations in an unsustainable way. The micropropagation of A. satureioides will allow its massive propagation and it will settle a base for its domestication. For this, a clone denominated as M1-5 was first propagated by cuttings. Subsequently, nodal segments obtained from young stems were disinfected by a standard method and cultured on MS medium. These shoots were used as a source of explants for subsequent assays. For its in vitro establishment MS medium and WPM were tested. Once the culture was established, the responses of the explants to increasing concentrations of 6-benzylaminopurine (BAP) (0.0; 0.5; 2.5 and 5.0 μM) with and without 0.05 μM α-naphthalene acetic acid (NAA) on WPM as basal medium were studied during 35 days. The proliferation of buds, the presence of callus and the number and length of the roots were evaluated. All of the “macela” cuttings in vivo propagated rooted and developed satisfactorily under the conditions tested. The application of 5.0 μM BAP alone generated the best multiplication rate, so it was selected as the multiplication medium. De novo shoots rooted spontaneously and finally, transferred to the greenhouse. Here in it was possible to establish a micropropagation protocol not only for the production of plantlets of selected clones but also for the application of biotechnological tools in the development of A. satureioides germplasm.

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Ahmed, Shehnaz Maqbool, A. H. Farooqui, Tausif S. Khan, Aayasha, and R. A. Chaudhary. "MANAGEMENT OF DYSMENORRHEA IN UNANI SYSTEM OF MEDICINE-A REVIEW." Indian Journal of Unani Medicine 15, no. 01 (2022): 56–62. http://dx.doi.org/10.53390/ijum.2022.15110.

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Dysmenorrhea is pain related with menstruation in Unani medicine, and ancient texts are abundant with traditional knowledge for managing menstrual pain.It is the most frequent gynecologic condition among female teenagers, affecting more than half of women between the ages of 18 and 25 years. It is characterized by painful cramps in the lower abdomen that are accompanied by one or more symptoms such as perspiration, lower backache, exhaustion, diarrhea, headache, nausea, vomiting, dizziness, and syncope in severe instances. Because conventional medicines often do not completely relieve pain and have their own side effects on the human body, it is necessary to understand the traditionally documented therapeutic options that have no adverse effects on the human body. The many causes and treatments for dysmenorrhea have been discussed in the unani literature under the category of waje rehm / dard rehm / usre tams. According to Unani manuscripts, the main management strategy is to induce analgesia and address the underlying cause of usr-i-tamth, which includes aberrant temperament, monthly irregularities/uterine disorders, as well as psychological and environmental variables. Unani drugs having emmenagogue, antispasmodic, anti-inflammatory, and analgesic are helpful in the treatment of usr-i-tamth.Herbs including Apium graveolens, Cuminum cyminum, Foeniculum vulgare, Matricaria chamomilla, and Nigella sativa have the aforementioned qualities, and their usefulness in usr-i-tamth has been scientifically verified. Validation and preservation of traditional knowledge are thus necessary for future study and important for usage in the modern period. The focus of the review study is on the treatment of dysmenorrhea in the unani medical system. It also goes over some of the herbal medicines and unani compound formulations that are used to treat dysmenorrhea.

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SHAHRAJABIAN, Mohamad Hesam, and Wenli SUN. "Asparagus (Asparagus officinalis L.) and pennyroyal (Mentha pulegium L.), impressive advantages with wondrous health-beneficial phytochemicals." Notulae Scientia Biologicae 14, no. 2 (May 30, 2022): 11212. http://dx.doi.org/10.55779/nsb14211212.

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Asparagus (Asparagus officinalis L.), belonging to the Asparagaceae family and has substantial medicinal properties. The name for asparagus comes from the Greek meaning sprout or shoot. This review aims to summarize the most important traditional and modern health benefits and pharmaceutical advantages of asparagus. This manuscript included randomized control experiments, review articles, observational and analytical studies, which have been surveyed in Google Scholar, Scopus, Research Gate and PubMed. We screened the articles first by reviewing titles and abstracts and subsequently reading the whole manuscript of those publications deemed suitable. The searches focused on publication from 1980 to January 2022. The most notable volatile organic compounds responsible for the smell are methanethiol, dimethyl sulfide, dimethyl disulfide, dimethyl sulfoxide and dimethyl sulfone. The most important health benefits of asparagus are antitumor, hepatoprotective, antioxidant, hypocholesterolemic, neuroprotective, immunoprotective, antimutagenic and hypoglycemic activities. The major pennyroyal (Mentha pulegium L.) essential oils are pulegone, menthone, isomenthone, piperitone, mentol, neo-menthol and 3-Octanol. The major health benefits of pennyroyal are antiseptic, depurative, digestive, anti-rheumatic, anti-arthritic, antimicrobial, antibacterial, stomachic, astringent, emmenagogue, decongestant and insecticide. Due to its pharmacological activities, asparagus is a high potential medicinal herb and the suggestion is to increases by doing research in both safety and efficacy. Natural herbal medicines which are also non-synthetic drug, super-fruit and functional foods is recommended and medicinal plants could be considered as organic super-fruit in all over the world. The phytochemical and pharmacological characteristics of asparagus show that asparagus is one of the most important medicinal plants in both traditional and modern pharmaceutical sciences. Pennyroyal has notable promising health benefits, and its phytochemical and pharmacological benefits indicate its important to be utilized in modern medicinal studies. This review also suggests more evidences for other researchers to use asparagus and pennyroyal as the ancient efficacious natural drugs.

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Mvondo, Marie Alfrede, Aude Jaelle Touomo Sakock, Sylvin Benjamin Ateba, Charline Florence Awounfack, Telesphore Nanbo Gueyo, and Dieudonné Njamen. "Emmenagogue properties of Milicia excelsa (Welw.) C.C. Berg (Moraceae) based, at least in part, on its ability to correlate the activity of the hypothalamic-pituitary axis to that of the ovaries." Journal of Ethnopharmacology 206 (July 2017): 283–89. http://dx.doi.org/10.1016/j.jep.2017.06.005.

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Journal articles on the topic 'Emmenagogues'

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