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Journal articles on the topic 'Emphyseme pulmonaire lobaire'

Author: Grafiati

Published: 4 June 2021

Last updated: 4 February 2022

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1

Absher, Dale R., Vesna Martich Kriss, and Carol M. Cottrill. "Lobar emphysema due to anomalous aortic origin of the left pulmonary artery." Cardiology in the Young 9, no. 3 (May 1999): 327–30. http://dx.doi.org/10.1017/s1047951100005035.

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AbstractThe unusual case of an infant with aortic origin of the left pulmonary artery is presented. The patient developed a rare complication of lobar emphysema due to bronchial compression from the enlarged right pulmonary artery. Operative anastomosis of the left pulmonary artery to the pulmonary trunk was successful, with subsequent resolution of the lobar emphysema.

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2

Gonçalves, Carlos Alberto, Valdemar Martins, António Ochoa, and Pedro Carvalho. "PULMONARY LOBAR INTERSTITIAL EMPHYSEMA." Fetal and Pediatric Pathology 28, no. 4 (January 2009): 192–97. http://dx.doi.org/10.1080/15513810902984160.

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3

Berlinger, Norman T., Dennis P. Porto, and Theodore R. Thompson. "Infantile Lobar Emphysema." Annals of Otology, Rhinology & Laryngology 96, no. 1 (January 1987): 106–11. http://dx.doi.org/10.1177/000348948709600124.

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Infantile lobar emphysema is a symptom complex representing a spectrum of diseases characterized by overdistention of a pulmonary lobe by a check valve mechanism. The earlier in life infantile lobar emphysema presents, the more severe are the symptoms. Half of the cases appear in the first 4 weeks of life. The chest radiograph is the best diagnostic tool but can be misinterpreted. Computed tomography sometimes discloses the cause, which appears to be bronchial obstruction in 25% of cases. The bronchial obstruction may be due to intrinsic defects or to extrinsic compression. Bronchoscopy should be performed only in certain cases and then only with careful anesthetic management.

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4

Glüer, Sylvia, Marc Reismann, and Benno M. Ure. "Congenital Lobar Emphysema." Annals of Thoracic Surgery 85, no. 2 (February 2008): 665. http://dx.doi.org/10.1016/j.athoracsur.2007.06.021.

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5

Rajan, R. S., and OP Yadava. "Congenital lobar emphysema." Indian Journal of Thoracic and Cardiovascular Surgery 4, no. 1 (January 1985): 89–91. http://dx.doi.org/10.1007/bf02664097.

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6

Regier, Penny J., Aitor Gallastegui, and William F. Craft. "Successful Treatment of Congenital Lobar Emphysema in Multiple Lung Lobes in an English Bulldog Puppy." Journal of the American Animal Hospital Association 57, no. 2 (January 15, 2021): 96–100. http://dx.doi.org/10.5326/jaaha-ms-7088.

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ABSTRACT A 5 mo old male intact English bulldog was evaluated at a veterinary referral hospital for acute respiratory distress and chronic difficulty breathing. Thoracic radiographs revealed multifocal pulmonary hyperinflation and hyperlucency suspected in the left caudal and accessory lung lobes. A thoracic computed tomography scan identified severe diffuse enlargement of the caudal subsegment of the left cranial lung lobe and the dorsal process of the accessory lung lobe, with parenchymal hypoattenuation, rounded margins, and thin pulmonary vessels. Based on clinical signs and imaging findings, he was diagnosed with suspect congenital lobar emphysema in multiple lung lobes. A median sternotomy was performed, which revealed a hyperinflated, emphysematous left cranial lung lobe (caudal subsegment) and accessory lung lobe for which two lung lobectomies were performed. The remaining lung lobes were small and atelectatic. Histopathology revealed bronchial cartilage hypoplasia and aplasia and findings consistent with congenital lobar emphysema. The puppy recovered well from surgical treatment of congenital lobar emphysema, requiring multiple lung lobectomies, with subsequent computed tomography–evidenced re-expansion of the remaining lung lobes 3 mo after surgery. The patient is still alive 1 yr after surgery with a normal activity level and no evidence of respiratory compromise.

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7

Theilig, Dorothea, Ralf-Harto Huebner, Konrad Neumann, Alexander Poellinger, and Felix Doellinger. "Selecting Patients for Lobar Lung Volume Reduction Therapy: What Quantitative Computed Tomography Parameters Matter?" RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren 191, no. 01 (October 11, 2018): 40–47. http://dx.doi.org/10.1055/a-0638-0058.

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Purpose Evaluation of emphysema distribution with quantitative computed tomography (qCT) prior to endoscopic lung volume reduction (ELVR) is recommended. The aim of this study was to determine which of the commonly assessed qCT parameters prior to endoscopic lung volume reduction (ELVR) best predicts outcome of treatment. Materials and Methods 50 patients who underwent technically successful ELVR at our institution were retrospectively analyzed. We performed quantitative analysis of the CT scans obtained prior to ELVR and carried out Mann-Whitney U-tests and a logistic regression analysis to identify the qCT parameters that predict successful outcome of ELVR in terms of improved forced expiratory volume in 1 second (FEV1). Results In the Mann-Whitney U-test, the interlobar emphysema heterogeneity index (p = 0.008) and the pulmonary emphysema score (p = 0.022) showed a statistically significant difference between responders and non-responders. In multiple logistic regression analysis only the interlobar emphysema heterogeneity index (p = 0.008) showed a statistically significant impact on the outcome of ELVR, while targeted lobe volume, total lung volume, targeted lobe emphysema score and total lung emphysema score did not. Conclusion Of all commonly assessed quantitative CT parameters, only the heterogeneity index definitely allows prediction of ELVR outcome in patients with advanced chronic obstructive pulmonary disease (COPD). Key Points Citation Format

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8

Walsh, Timothy Andrew, Krishna Revanna Gopagondanahalli, and Atul Malhotra. "Williams-Beuren Syndrome and Congenital Lobar Emphysema: Uncommon Association with Common Pathology?" Case Reports in Pediatrics 2017 (2017): 1–4. http://dx.doi.org/10.1155/2017/3480980.

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Introduction. Congenital lobar emphysema (CLE) and Williams-Beuren Syndrome are two rare conditions that have only been reported together in a single case study. Case Presentation. We report another case of a male Caucasian newborn with nonspecific initial respiratory distress, with detection of CLE on repeat chest X-ray on Day 25 of life and concurrent ventricular septal defect, supravalvular aortic stenosis, and branch pulmonary stenosis, in whom a 7q11.23 deletion consistent with Williams-Beuren Syndrome was made. Conclusion. A diagnosis of congenital lobar emphysema should prompt further screening for congenital heart disease and genetic deletion, and further research is needed to investigate the role of elastin gene mutation in the development of the neonatal lung.

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9

Al Alaiyan, Saleh, Abdulhakiem Katan, and Omar Galal. "Infantile Lobar Emphysema and Absent Pulmonary Valve Syndrome." Annals of Saudi Medicine 16, no. 4 (July 1996): 444–46. http://dx.doi.org/10.5144/0256-4947.1996.444.

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10

Mirza, Bilal, AfsheenBatool Raza, Iftikhar Ijaz, Lubna Ijaz, Farah Naz, and Afzal Sheikh. "Intralobar pulmonary sequestration masquerading as congenital lobar emphysema." Journal of Indian Association of Pediatric Surgeons 16, no. 1 (2011): 15. http://dx.doi.org/10.4103/0971-9261.74515.

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11

Yamane, Masaomi, Daisuke Okutani, Seiichiro Sugimoto, Shinichi Toyooka, Motoi Aoe, Megumi Okazaki, Yoshifumi Sano, and Hiroshi Date. "Native Lung-sparing Lobar Transplantation for Pulmonary Emphysema." Journal of Heart and Lung Transplantation 27, no. 9 (September 2008): 1046–49. http://dx.doi.org/10.1016/j.healun.2008.05.025.

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12

Bouyssou, Sarah, Inigo Sanz, Francesco Marchesi, and Caroline Eivers. "Radiographic, computed tomographic and histopathological characteristics of multilobar congenital pulmonary emphysema in a puppy." Veterinary Record Case Reports 8, no. 2 (June 2020): e001125. http://dx.doi.org/10.1136/vetreccr-2020-001125.

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A 10-week-old male entire Labrador retriever was presented for evaluation of acute-onset coughing and respiratory distress. Radiographic and CT examination of the thorax revealed the presence of multifocal and numerous gas-filled cystic lesions throughout the lung field and a mild pneumothorax. Gross pathological and histopathological findings were consistent with congenital lobar emphysema due to bronchial cartilage dysplasia/hypoplasia and possible congenital bronchiectasis. This is the first report describing combined radiographic and CT characteristics of a rare case of multilobar congenital pulmonary emphysema in a puppy.

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13

Moslehi, MohammadAshkan. "Congenital lobar emphysema: Pitfalls in diagnosis." Lung India 33, no. 5 (2016): 585. http://dx.doi.org/10.4103/0970-2113.189008.

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14

Sadaqat, Mir, JavaidA Malik, and Raiesa Karim. "Congenital lobar emphysema in an adult." Lung India 28, no. 1 (2011): 67. http://dx.doi.org/10.4103/0970-2113.76307.

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15

Critchley, P. S., C. P. Forrester-Wood, and P. D. Ridley. "Adult congenital lobar emphysema in pregnancy." Thorax 50, no. 8 (August 1, 1995): 909–10. http://dx.doi.org/10.1136/thx.50.8.909.

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16

K., Aditya, Parvathi K., and Prabhakar V. "A case report of congenital lobar emphysema." International Journal of Contemporary Pediatrics 7, no. 4 (March 21, 2020): 945. http://dx.doi.org/10.18203/2349-3291.ijcp20201004.

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Congenital lobar emphysema (CLE), also known as congenital alveolar overdistension, is a developmental anomaly of the lower respiratory tract that is characterized by hyperinflation of one or more of the pulmonary lobes. CLE is a rare congenital malformation with a prevalence of 1 in 20,000 to 1 in 30,000. We are reporting a 4-month-old boy presented with complaints of cough and cold for 3 days with history of similar complaints in the past at age of 1month and 2 months. Investigations revealed hyperlucency of left upper zone with tracheal shift and mild shift of the heart to the right. Elective Left Upper Lung Lobectomy was done and Appropriate supportive therapy given and child recovered well.

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17

Knollmann, Daniela, Jerome Avondo, Andreas Meyer, and Wolfgang Michael Schaefer. "Volume/perfusion ratio from lung SPECT/CT." Nuklearmedizin 57, no. 01 (January 2018): 31–34. http://dx.doi.org/10.3413/nukmed-0928-17-09.

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SummaryAim: In pulmonary emphysema lung volume reduction procedures (LVRP) can optimize respiratory pump function. Identification of the most affected lobe can be reached using relative lobar volume (relVol) from CT, but this approach disregards the corresponding lobar perfusion. The aim of the study was therefore to establish a new parameter combining relVol from CT and relative perfusion (relPerf) from perfusion SPECT as a single parameter (volume/perfusion ratio (VPR)) to optimize the identification procedure.Methods: As a proof of principle VPR was calculated from hybrid V-/P-SPECT/CT scans from 20 patients with severe pulmonary emphysema (SPE) before LVRP. Lung V-/P-SPECT/CT (Siemens SymbiaT) was done with Technegas and 99mTc-MAA. Quantification of lobar perfusion from scintigraphy and volume from CT was performed using “HERMES Hybrid 3D – Lung Lobe Quantification”. Using normal ranges – from 12 patients with suspected pulmonary embolism and normal lung structure and perfusion – all lobes were classified as normal or abnormal to identify targets for LVRP.Results: Normal values for VPR: right upper lobe 1.09 ± 0.10, middle lobe 1.31 ± 0.31, right lower lobe 0.87 ± 0.08; left upper lobe 1.09 ± 0.11, left lower lobe 0.87 ± 0.12. In the 20 SPE patients there were only 7 lobes with pathological values for rel- Vol, 14 lobes with pathological values for rel- Perf but 31 lobes with pathological VPR.Conclusion: Estimation of VPR from lung SPECT/CT enables a combined view of lobar volume and perfusion with one parameter. In SPE patients VPR allows identifying possible target structures with much higher sensitivity than when using relPerf or relVol alone. The specificity and the prognostic value of this new parameter have to be tested in a clinical trial.

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18

Mink, S. N., H. W. Unruh, and L. Oppenheimer. "Vascular and interstitial mechanics in canine pulmonary emphysema." Journal of Applied Physiology 59, no. 6 (December 1, 1985): 1704–15. http://dx.doi.org/10.1152/jappl.1985.59.6.1704.

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We examined the changes in vascular and interstitial mechanics in pulmonary emphysema (PE) using a canine lobar model. PE was produced in the left lower lobe (LLL) of five dogs (group E) by six weekly intrabronchial instillations of the enzyme papain. In five control dogs (group C), a normal saline solution was used. In our in vivo preparation, vascular flow (Q) to the LLL was measured. Inflow (Ppa) and outlow (Pv) pressures to the LLL could be varied independently. The relationship of Ppa to Q was examined in zones 2 and 3 of West. The slope of the Ppa-Q relationship was used to determine vascular conductance, whereas the extrapolation to zero flow in zone 2 conditions represented the mean pressure required for vascular recruitment (Pi). Lobar weight gain was measured continuously. Following step increases in Ppa, the rapid increase in wet weight measured when Q to the LLL was zero was used to obtain vascular compliance (C). Subsequent slow increases in wet weight were used to determine the rate of fluid exchange with the interstitium (Qf). The slope of the Qf-Ppa relationship represented fluid conductance (Kf). The extrapolation to zero Qf gave the minimal pressure required for continuous edema formation (Pm). Compared with group C, vascular conductance (G) decreased and Pi increased in group E, whereas fluid conductance (Kf) and Pm increased. The decrease in G most likely resulted from the loss of vascular cross-sectional area in emphysematous lungs, whereas the increase in Pi was possibly due to mechanical changes in the lung interstitium which increased vessel closure. We propose that the increase in Kf in group E reflected an increase in interstitial conductance, such that due to structural changes in the interstitium in emphysematous lungs, tissue resistance to fluid flux decreased.

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19

Doull, Iolo J. M., Gary J. Connett, and John O. Warner. "Bronchoscopic appearances of congenital lobar emphysema." Pediatric Pulmonology 21, no. 3 (March 1996): 195–97. http://dx.doi.org/10.1002/(sici)1099-0496(199603)21:3<195::aid-ppul9>3.0.co;2-p.

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20

Shen, Cheng, and Guowei Che. "Congenital Lobar Emphysema in an Elderly Patient." American Journal of Respiratory and Critical Care Medicine 202, no. 11 (December 1, 2020): 1579–80. http://dx.doi.org/10.1164/rccm.202004-1337im.

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21

Chapdelaine, Joyaube, Mona Beaunoyer, Dickens St-Vil, Luc L. Oligny, Laurent Garel, Andreana Bütter, and Maria Di Lorenzo. "Unilobar congenital pulmonary lymphangiectasis mimicking congenital lobar emphysema: an underestimated presentation?" Journal of Pediatric Surgery 39, no. 5 (May 2004): 677–80. http://dx.doi.org/10.1016/j.jpedsurg.2004.01.044.

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22

Khalid, M., S. Saleemi, and B. Khan. "Congenital lobar emphysema in adult: A rare case report." Respiratory Medicine CME 3, no. 3 (2010): 150–52. http://dx.doi.org/10.1016/j.rmedc.2009.09.010.

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23

Khemiri, Monia, Monia Ouederni, Fafany Ben Mansour, and Siham Barsaoui. "Bronchogenic cyst: An uncommon cause of congenital lobar emphysema." Respiratory Medicine 102, no. 11 (November 2008): 1663–66. http://dx.doi.org/10.1016/j.rmed.2008.07.001.

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24

Demir, Ömer Faruk, Melih Hangul, and Mehmet Kose. "Congenital lobar emphysema: diagnosis and treatment options." International Journal of Chronic Obstructive Pulmonary Disease Volume 14 (May 2019): 921–28. http://dx.doi.org/10.2147/copd.s170581.

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25

Bawazir, OsamaAbdullah. "Congenital lobar emphysema: Thoracotomy versus minimally invasive surgery." Annals of Thoracic Medicine 15, no. 1 (2020): 21. http://dx.doi.org/10.4103/atm.atm_203_19.

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26

Bolles, Jonathan A., Leonard Deal, and Matthew Gilman. "Rare Presentation of Congenital Lobar Emphysema in Adulthood." Clinical Pulmonary Medicine 10, no. 6 (November 2003): 305–7. http://dx.doi.org/10.1097/01.cpm.0000097784.93282.11.

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27

Torán, N., C. Ruiz de Miguel, J. Reig, and M. Garcia-Bonafé. "Lobar Emphysema Associated with Patent Ductus Arteriosus and Pulmonary Obstructive Vascular Disease." Pediatric Pathology 9, no. 2 (January 1989): 163–70. http://dx.doi.org/10.3109/15513818909022344.

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28

Pratap, Akshay, Nisha keshari Bhatta, Satyendra narayan Singh, Sagar Pandey, Amit Agrawal, Rohit prasad Yadav, Gunraj Paudel, and Ramasubramanian Lakshmi. "Delayed presentation of congenital pulmonary airway malformation type 4 mimicking lobar emphysema." Pediatrics International 50, no. 3 (June 2008): 400–402. http://dx.doi.org/10.1111/j.1442-200x.2008.02601.x.

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29

Shen, Mali, Eric D. Tenda, William McNulty, Justin Garner, Hasti Robbie, Valentina Luzzi, Arafa M. Aboelhassan, et al. "Quantitative Evaluation of Lobar Pulmonary Function of Emphysema Patients with Endobronchial Coils." Respiration 98, no. 1 (2019): 70–81. http://dx.doi.org/10.1159/000499622.

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30

Wiener, Eugene S. "Lobar emphysema associated with patent ductus arteriosus and pulmonary obstructive vascular disease." Journal of Pediatric Surgery 25, no. 9 (September 1990): 1003. http://dx.doi.org/10.1016/0022-3468(90)90266-c.

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31

Ewing-Bui, David, and Steven N. Mink. "Interdependence of flow between lobes reduces maximal emptying postresection in dogs." Journal of Applied Physiology 92, no. 1 (January 1, 2002): 100–108. http://dx.doi.org/10.1152/jappl.2002.92.1.100.

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The effect of pulmonary resection on the maximal emptying of the remaining lobes was examined in an open-chest preparation in normal canine lungs and in a unilobar papain emphysema model. The objectives were to determine whether, compared with when both lungs were deflated (BL), maximal emptying of the normal lower lobes or the emphysematous right lower lobe would be altered 1) when acute pneumonectomy of the contralateral lung was performed (OL) and 2) when the lower lobe deflated alone (LA). The alveolar capsule technique was used to measure alveolar pressures (Palv) at 75, 50, and 30% lobar vital capacity (VC). During forced deflation, the maximal rates of deflation (dPalv/d t) and flows (lobarV˙max) of the lower lobes were determined under the three different conditions. The Pitot-static tube technique was used to measure intrabronchial pressures and to estimate bronchial area and compliance in which values were obtained at the same central airway during the conditions studied. The results showed that, compared with BL and OL, dPalv/d t and lobarV˙max decreased during LA ( P < 0.05). These findings were due to a reduction in bronchial area during LA that limited flow at a lower maximal value compared with BL. This decrease in area appeared to be due to a change in bronchial pressure area behavior that resulted in a smaller bronchial area during LA for similar transmural pressures between conditions. There were no differences in findings between normal and emphysematous lobes. This study suggested that removal of lobes may alter the pressure area behavior of central airways. Possible mechanisms considered were differences in axial tension between conditions, negative effort dependence, or parenchymal-bronchial interdependence that may be relevant to understanding the dynamic collapsibility of central as well as intraparenchymal airways.

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32

Nakata, Tomohiro, Tadashi Ikeda, Hiroshi Date, Hiraku Doi, Shiro Baba, Takuya Hirata, and Ryuzo Sakata. "Ventricular Septal Defect Complicated by Infantile Lobar Emphysema." Annals of Thoracic and Cardiovascular Surgery 20, Supplement (2014): 901–3. http://dx.doi.org/10.5761/atcs.cr.13-00186.

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33

Parveen, Nuzhat, and Tarannum Khatun. "Congenital Pulmonary Airway Malformation (CPAM) follow up from 23 week of gestation." Med Phoenix 2, no. 1 (October 13, 2017): 63–66. http://dx.doi.org/10.3126/medphoenix.v2i1.18390.

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The development of the respiratory system starts at 3 weeks of gestation, and aberrations in developmental processes may result in structural abnormalities collectively referred to as bronchopulmonary foregut malformations. These lesions include congenital cystic adenomatoid malformations (CCAMs), sequestrations and infantile lobar emphysema. Case presented is of right lung CCAM diagnosed at 23 weeks of gestation, followed during antenatal periods for complications, delivered at 39 weeks, planned thoracotomy with lobectomy done on 3rd day of life and followed up till 1 year. Detailed anomaly scan and close monitoring for structural abnormalities of fetus is needed for appropriate management. Relationship of CPAM with early pregnancy severe infections remains to be established.Med Phoenix Vol.2(1) July 2017, 63-66

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34

Hill, Ronald C., Vito Mantese, Alexander Spock, and Walter G. Wolfe. "Management of an unusual case of congenital lobar emphysema." Pediatric Pulmonology 5, no. 4 (1988): 252–54. http://dx.doi.org/10.1002/ppul.1950050413.

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35

Douwes, J. M., R. F. H. M. Tummers, A. G. Hensens, M. Wagenaar, and B. J. Thio. "Congenital lobar emphysema in a teenager presented by a persisting pneumothorax." Respiratory Medicine CME 2, no. 4 (2009): 162–63. http://dx.doi.org/10.1016/j.rmedc.2009.01.015.

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36

Cataneo, Daniele Cristina, Olavo Ribeiro Rodrigues, Erica Nishida Hasimoto, Aurelino Fernandes Schmidt Jr, and Antonio Jose Maria Cataneo. "Congenital lobar emphysema: 30-year case series in two university hospitals." Jornal Brasileiro de Pneumologia 39, no. 4 (June 2013): 418–26. http://dx.doi.org/10.1590/s1806-37132013000400004.

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OBJECTIVE: To review the cases of patients with congenital lobar emphysema (CLE) submitted to surgical treatment at two university hospitals over a 30-year period. METHODS: We reviewed the medical records of children with CLE undergoing surgical treatment between 1979 and 2009 at the Botucatu School of Medicine Hospital das Clínicas or the Mogi das Cruzes University Hospital. We analyzed data regarding symptoms, physical examination, radiographic findings, diagnosis, surgical treatment, and postoperative follow-up. RESULTS: During the period studied, 20 children with CLE underwent surgery. The mean age at the time of surgery was 6.9 months (range, 9 days to 4 years). All of the cases presented with symptoms at birth or during the first months of life. In all cases, chest X-rays were useful in defining the diagnosis. In cases of moderate respiratory distress, chest CT facilitated the diagnosis. One patient with severe respiratory distress was misdiagnosed with hypertensive pneumothorax and underwent chest tube drainage. Only patients with moderate respiratory distress were submitted to bronchoscopy, which revealed no tracheobronchial abnormalities. The surgical approach was lateral muscle-sparing thoracotomy. The left upper and middle lobes were the most often affected, followed by the right upper lobe. Lobectomy was performed in 18 cases, whereas bilobectomy was performed in 2 (together with bronchogenic cyst resection in 1 of those). No postoperative complications were observed. Postoperative follow-up time was at least 24 months (mean, 60 months), and no late complications were observed. CONCLUSIONS: Although CLE is an uncommon, still neglected disease of uncertain etiology, the radiological diagnosis is easily made and surgical treatment is effective.

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37

Dembinski, J., A. Heep, N. Kau, G. Knöpfle, and P. Bartmann. "CT Imaging of Pulmonary Lobar Interstitial Emphysema in a Spontaneous Breathing Preterm Infant." American Journal of Perinatology 19, no. 6 (2002): 285–90. http://dx.doi.org/10.1055/s-2002-34466.

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38

Mendeloff, Eric N. "Sequestrations, congenital cystic adenomatoid malformations, and congenital lobar emphysema." Seminars in Thoracic and Cardiovascular Surgery 16, no. 3 (September 2004): 209–14. http://dx.doi.org/10.1053/j.semtcvs.2004.08.007.

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39

Rusakow, Lee S., and Smriti Khare. "Radiographically occult congenital lobar emphysema presenting as unexplained neonatal tachypnea." Pediatric Pulmonology 32, no. 3 (September 2001): 246–49. http://dx.doi.org/10.1002/ppul.1114.abs.

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40

Neder, J. Alberto, and Denis E. O’Donnell. "Update on Nonsurgical Lung Volume Reduction Procedures." Canadian Respiratory Journal 2016 (2016): 1–6. http://dx.doi.org/10.1155/2016/6462352.

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There has been a surge of interest in endoscopic lung volume reduction (ELVR) strategies for advanced COPD. Valve implants, coil implants, biological LVR (BioLVR), bronchial thermal vapour ablation, and airway stents are used to induce lung deflation with the ultimate goal of improving respiratory mechanics and chronic dyspnea. Patients presenting with severe air trapping (e.g., inspiratory capacity/total lung capacity (TLC) < 25%, residual volume > 225% predicted) and thoracic hyperinflation (TLC > 150% predicted) have the greatest potential to derive benefit from ELVR procedures. Pre-LVRS or ELVR assessment should ideally include cardiological evaluation, high resolution CT scan, ventilation and perfusion scintigraphy, full pulmonary function tests, and cardiopulmonary exercise testing. ELVR procedures are currently available in selected Canadian research centers as part of ethically approved clinical trials. If a decision is made to offer an ELVR procedure, one-way valves are the first option in the presence of complete lobar exclusion and no significant collateral ventilation. When the fissure is not complete, when collateral ventilation is evident in heterogeneous emphysema or when emphysema is homogeneous, coil implants or BioLVR (in that order) are the next logical alternatives.

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41

Dutta, Hemonta, Madhuchanda Bora, and Diganta Saikia. "Evaluation of Clinical Outcomes in Neonates Undergoing Lung Resection for Congenital Lesions." Journal of Child Science 07, no. 01 (January 2017): e4-e9. http://dx.doi.org/10.1055/s-0037-1603772.

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Objective The purpose of this study is to review our experience with neonates and infants with congenital lung lesions emphasizing natural history, management, and outcomes. Methods A total of 29 neonates and infants presented with congenital lung lesions between 2000 and 2015. Two patients died before surgery due to complications, and one patient refused surgery. Overall, 26 of them were subjected to surgical treatment and were included in the study. Demographic data, indications for surgery, operative procedure, complications, hospital stay, and follow-up were assessed. Results A total of 26 children aged 5 to 122 days (mean: 35.5 days, 14 males) presented with various congenital lung malformations: congenital lobar emphysema in 10, congenital cystic adenomatous malformation in 8, bronchogenic cyst in 5, and pulmonary sequestration in 3 patients. Respiratory distress and respiratory tract infection were the most common presenting symptoms noted in 22 patients. In three patients the lesion was detected incidentally on chest X-ray. Lobectomy was the most common operation (19/26). Postoperative complications were noted in 12 patients. One patient died due to postoperative sepsis. Postoperative ventilation was required in 24 patients. Patients in the asymptomatic group recovered without any complications. The follow-up period ranged from 3 months to 15 years (median: 76.3 months). Only 12 patients received epidural anesthesia and had a better recovery than the other patients. Conclusion Congenital lobar emphysema was the most common congenital lung lesion in our series. Respiratory distress and respiratory infection were the most common symptoms. Neonates and infants tolerated lung resection well. Use of epidural anesthesia led to less postoperative complications.

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Imai, Yukihiro, and Eugene J. Mark. "Cystic Adenomatoid Change Is Common to Various Forms of Cystic Lung Diseases of Children." Archives of Pathology & Laboratory Medicine 126, no. 8 (August 1, 2002): 934–40. http://dx.doi.org/10.5858/2002-126-0934-cacict.

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Abstract Context.—Congenital cystic adenomatoid malformation, intralobar sequestration, extralobar sequestration, bronchopulmonary foregut malformation, bronchial atresia, and lobar emphysema generally are treated as separate entities, but there are commonalities among them. Objective.—To clarify the identity of congenital cystic adenomatoid malformation in relation to other cystic diseases. Design.—We studied 10 consecutive cases of surgically resected cystic lung disease in children. We studied the bronchial and vascular trees by mapping bronchi, pulmonary blood vessels, systemic blood vessels, the size and configuration of cysts, and associated scarring. Results.—The cystic lesions proved to be the following: 1 case of congenital cystic adenomatoid malformation, 2 cases of bronchial atresia with congenital cystic adenomatoid malformation, 1 hybrid case of congenital cystic adenomatoid malformation and intralobar sequestration, 1 case of intralobar sequestration with an aberrant hilum, 3 cases of intralobar sequestration with bronchial obliteration, 1 case of lung abscess, and 1 case of lobar emphysema. Congenital cystic adenomatoid malformation was the sole pathologic diagnosis in 1 case, but 7 other specimens had cystic adenomatoid change to various degrees. There was no bronchial connection between the cystic lesions and the patient's airway in 8 cases. The bronchial tree was absent in the cystic lung in 2 cases. Bronchus tapered into scar near the cystic lesion in 4 cases. Only 1 case had no significant bronchial abnormality. Conclusion.—The high incidence of cystic adenomatoid change in cystic lung disease associated with an abnormality of the bronchial tree suggests that cystic adenomatoid change may develop together with and be related to other congenital or acquired conditions in the lung.

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Argula, Rahul, Viswanathan Ramakrishnan, and Charlie Strange. "Baseline Lobar Perfusion Impacts Exercise Response to Endobronchial Valve Therapy in Advanced Pulmonary Emphysema." Chest 140, no. 4 (October 2011): 924A. http://dx.doi.org/10.1378/chest.1119860.

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Bakker, Jens T., Karin Klooster, Rozemarijn Vliegenthart, and Dirk-Jan Slebos. "Measuring pulmonary function in COPD using quantitative chest computed tomography analysis." European Respiratory Review 30, no. 161 (July 13, 2021): 210031. http://dx.doi.org/10.1183/16000617.0031-2021.

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COPD is diagnosed and evaluated by pulmonary function testing (PFT). Chest computed tomography (CT) primarily serves a descriptive role for diagnosis and severity evaluation. CT densitometry-based emphysema quantification and lobar fissure integrity assessment are most commonly used, mainly for lung volume reduction purposes and scientific efforts.A shift towards a more quantitative role for CT to assess pulmonary function is a logical next step, since more, currently underutilised, information is present in CT images. For instance, lung volumes such as residual volume and total lung capacity can be extracted from CT; these are strongly correlated to lung volumes measured by PFT.This review assesses the current evidence for use of quantitative CT as a proxy for PFT in COPD and discusses challenges in the movement towards CT as a more quantitative modality in COPD diagnosis and evaluation. To better understand the relevance of the traditional PFT measurements and the role CT might play in the replacement of these parameters, COPD pathology and traditional PFT measurements are discussed.

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Okur, Hamit, Mustafa Küçükaydin, Adnan Öztürk, Süleyman Balkanli, and Ali Bozkurt. "Giant bronchogenic cyst presenting as a lobar emphysema in a newborn." Annals of Thoracic Surgery 62, no. 1 (July 1996): 276–78. http://dx.doi.org/10.1016/0003-4975(96)00265-2.

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Hartman, Jorine E., Pallav L. Shah, Frank Sciurba, Felix J. F. Herth, Dirk‐Jan Slebos, F. J. F. Herth, D. Gompelmann, et al. "Endobronchial coils for emphysema: Dual mechanism of action on lobar residual volume reduction." Respirology 25, no. 11 (April 8, 2020): 1160–66. http://dx.doi.org/10.1111/resp.13816.

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Molinaro, Francesco, Rossella Angotti, Alfredo Garzi, Vincenzo Giuseppe Di Crescenzo, Antonio Cortese, and Mario Messina. "Prenatal diagnosis, 3-D virtual rendering and lung sparing surgery by ligasure device in a baby with “CCAM and intralobar pulmonary sequestration”." Open Medicine 11, no. 1 (January 1, 2016): 200–203. http://dx.doi.org/10.1515/med-2016-0038.

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AbstractCongenital cystic lung lesions are a rare but clinically significant group of anomalies, including congenital cystic adenomatoid malformation (CCAM), pulmonary sequestration, congenital lobar emphysema (CLE) and bronchogenic cysts. Despite the knowledge of these lesions increasing in the last years, some aspects are still debated and controversial. The diagnosis is certainly one aspect which underwent many changes in the last 15 years due to the improvement of antenatal scan and the introduction of 3-D reconstruction techniques. As it is known, a prompt diagnosis has an essential role in the management of these children. The new imaging studies as 3D Volume rendering system are the focus of this paper. We describe our preliminary experience in a case of hybrid lung lesion, which we approached by thoracoscopy after a preoperative study with 3D VR reconstruction. Our final balance is absolutely positive.

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Ure, Benno, Jens Dingemann, and Christoph Zoeller. "Perioperative Complications of Video-Assisted Thoracoscopic Pulmonary Procedures in Neonates and Infants." European Journal of Pediatric Surgery 28, no. 02 (March 6, 2018): 163–70. http://dx.doi.org/10.1055/s-0038-1636917.

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AbstractVideo-assisted thoracoscopic surgery (VATS) has gained broad acceptance among pediatric surgeons. Today, VATS can be regarded as a routine approach for various conditions in neonates and infants. However, there is a lack of information concerning the complications of thoracoscopic pulmonary surgery in neonates and infants. We aimed to review the available data. A systematic review of the literature was performed using PubMed. All publications reporting on VATS for pulmonary procedures in neonates and infants up to the age of 1 year were included. Articles were reviewed in detail for occurrence of perioperative complications and their treatment. Nine case series were eligible for analysis. Entities treated included lung sequestration, congenital pulmonary airway malformation, congenital lobar emphysema, and bronchogenic cyst. Case series reported on a total number of 135 patients. Complications occurred in 14 patients (10.4%). The major complication was an accidental transection of the middle lobar bronchus that concluded in a later resection of a prior unaffected lung lobe. Other relevant complications reported were bleeding in four patients (3.0%) and persistent air leak in four cases (3.0%). Infectious complications were reported in four patients (3.0%). Additionally, iatrogenic phrenic nerve paralysis occurred in one patient. There were no deaths related to the VATS technique. In 11 cases (8.1%), conversion to thoracotomy had been necessary. General recommendations on the treatment of complications could not be derived due to small patient numbers and lack of details of the complications reported. Reports on major complications of pulmonary VATS in neonates and infants below 1 year of age are scarce. As severe complications such as accidental bronchus transection have been described, feasibility of neonatal/infant VATS cannot be unequivocally confirmed. No literature-based recommendation can be given on the treatment of complications.

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Mani, Haresh, Eric Suarez, and J. Thomas Stocker. "The morphologic spectrum of infantile lobar emphysema: a study of 33 cases." Paediatric Respiratory Reviews 5 (January 2004): S313—S320. http://dx.doi.org/10.1016/s1526-0542(04)90056-5.

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Kohlhauser, Christina, Christian Popow, Thomas Helbich, Michael Hermon, Manfred Weninger, and Christian J. Herold. "Successful treatment of severe neonatal lobar emphysema by high-frequency oscillatory ventilation." Pediatric Pulmonology 19, no. 1 (January 1995): 52–55. http://dx.doi.org/10.1002/ppul.1950190108.

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