Academic literature on the topic 'Empty virus like particles'

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Journal articles on the topic "Empty virus like particles"

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Zoratto, Samuele, Thomas Heuser, Gernot Friedbacher, et al. "Adeno-Associated Virus-like Particles’ Response to pH Changes as Revealed by nES-DMA." Viruses 15, no. 6 (2023): 1361. http://dx.doi.org/10.3390/v15061361.

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Gas-phase electrophoresis on a nano-Electrospray Gas-phase Electrophoretic Mobility Molecular Analyzer (nES GEMMA) separates single-charged, native analytes according to the surface-dry particle size. A volatile electrolyte, often ammonium acetate, is a prerequisite for electrospraying. Over the years, nES GEMMA has demonstrated its unique capability to investigate (bio-)nanoparticle containing samples in respect to composition, analyte size, size distribution, and particle numbers. Virus-like particles (VLPs), being non-infectious vectors, are often employed for gene therapy applications. Foc
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Wu, Hui-Lin, Pei-Jer Chen, Jung-Jung Mu, et al. "Assembly of Hepatitis Delta Virus-like Empty Particles in Yeast." Virology 236, no. 2 (1997): 374–81. http://dx.doi.org/10.1006/viro.1997.8743.

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Hainisch, Edmund K., Christoph Jindra, Reinhard Kirnbauer, and Sabine Brandt. "Papillomavirus-Like Particles in Equine Medicine." Viruses 15, no. 2 (2023): 345. http://dx.doi.org/10.3390/v15020345.

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Papillomaviruses (PVs) are a family of small DNA tumor viruses that can induce benign lesions or cancer in vertebrates. The observation that animal PV capsid-proteins spontaneously self-assemble to empty, highly immunogenic virus-like particles (VLPs) has led to the establishment of vaccines that efficiently protect humans from specific PV infections and associated diseases. We provide an overview of PV-induced tumors in horses and other equids, discuss possible routes of PV transmission in equid species, and present recent developments aiming at introducing the PV VLP-based vaccine technology
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Li, T. C., Y. Yamakawa, K. Suzuki, et al. "Expression and self-assembly of empty virus-like particles of hepatitis E virus." Journal of virology 71, no. 10 (1997): 7207–13. http://dx.doi.org/10.1128/jvi.71.10.7207-7213.1997.

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Richterová, Zuzana, David Liebl, Martin Horák, et al. "Caveolae Are Involved in the Trafficking of Mouse Polyomavirus Virions and Artificial VP1 Pseudocapsids toward Cell Nuclei." Journal of Virology 75, no. 22 (2001): 10880–91. http://dx.doi.org/10.1128/jvi.75.22.10880-10891.2001.

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ABSTRACT Electron and confocal microscopy were used to observe the entry and the movement of polyomavirus virions and artificial virus-like particles (VP1 pseudocapsids) in mouse fibroblasts and epithelial cells. No visible differences in adsorption and internalization of virions and VP1 pseudocapsids (“empty” or containing DNA) were observed. Viral particles entered cells internalized in smooth monopinocytic vesicles, often in the proximity of larger, caveola-like invaginations. Both “empty” vesicles derived from caveolae and vesicles containing viral particles were stained with the anti-cave
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Hord, M., W. Villalobos, A. V. Macaya-Lizano, and C. Rivera. "Chayote Mosaic, a New Disease in Sechium edule Caused by a Tymovirus." Plant Disease 81, no. 4 (1997): 374–78. http://dx.doi.org/10.1094/pdis.1997.81.4.374.

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A sap-transmissible virus was isolated from chayote (Sechium edule) in Costa Rica. Infected plants showed chlorotic spots and rings, and blotchy mosaics, which often coalesced to give a complete mosaic and leaf deformation. By electron microscopy, spherical virus-like particles of approximately 29 nm in diameter were visible, and cytological changes associated with the chloroplasts were observed. The virus particles sedimented in sucrose density gradients as two components, a top component of empty protein shells and a bottom component of electron-dense particles. Electrophoretic analysis show
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Ammar, E. D., R. E. Gingery, and L. R. Nault. "Cytopathology and ultrastructure of mild and severe strains of maize chlorotic dwarf virus in maize and johnsongrass." Canadian Journal of Botany 71, no. 5 (1993): 718–24. http://dx.doi.org/10.1139/b93-083.

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In maize leaves experimentally infected with various isolates or strains of maize chlorotic dwarf virus, including a newly characterized strain (M1), and in naturally infected johnsongrass, only two types of cytoplasmic inclusions were consistently observed: (i) quasi-spherical electron-dense granular inclusions, and (ii) curved or straight bundles of fibrous inclusions. Both types were detected by light and (or) electron microscopy in vascular parenchyma and phloem cells, and less frequently in bundle-sheath and adjacent mesophyll cells. The dense granular inclusions usually contained numerou
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Huynh, Nhung T., Emma L. Hesketh, Pooja Saxena, et al. "Crystal Structure and Proteomics Analysis of Empty Virus-like Particles of Cowpea Mosaic Virus." Structure 24, no. 4 (2016): 567–75. http://dx.doi.org/10.1016/j.str.2016.02.011.

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Suárez, Cristina, María L. Salas, and Javier M. Rodríguez. "African Swine Fever Virus Polyprotein pp62 Is Essential for Viral Core Development." Journal of Virology 84, no. 1 (2009): 176–87. http://dx.doi.org/10.1128/jvi.01858-09.

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ABSTRACT One of the most characteristic features of African swine fever virus gene expression is its use of two polyproteins, pp220 and pp62, to produce several structural proteins that account for approximately 32% of the total protein virion mass. Equimolecular amounts of these proteins are the major components of the core shell, a thick protein layer that lies beneath the inner envelope, surrounding the viral nucleoid. Polyprotein pp220, which is located immediately underneath the internal envelope, is essential for the encapsidation of the core of the viral particle. In its absence, the in
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Ren, Jingshan, Xiangxi Wang, Ling Zhu, et al. "Structures of Coxsackievirus A16 Capsids with Native Antigenicity: Implications for Particle Expansion, Receptor Binding, and Immunogenicity." Journal of Virology 89, no. 20 (2015): 10500–10511. http://dx.doi.org/10.1128/jvi.01102-15.

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ABSTRACTEnterovirus 71 (EV71) and coxsackievirus A16 (CVA16) are the primary causes of the epidemics of hand-foot-and-mouth disease (HFMD) that affect more than a million children in China each year and lead to hundreds of deaths. Although there has been progress with vaccines for EV71, the development of a CVA16 vaccine has proved more challenging, and the EV71 vaccine does not give useful cross-protection, despite the capsid proteins of the two viruses sharing about 80% sequence identity. The structural details of the expanded forms of the capsids, which possess nonnative antigenicity, are n
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Dissertations / Theses on the topic "Empty virus like particles"

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Ross, James Finnian. "Reengineering bacterial toxins into virus-like particles." Thesis, University of Leeds, 2013. http://etheses.whiterose.ac.uk/6464/.

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The re-design and controlled self-assembly of natural systems into non-natural functional products is a quickly developing area of Synthetic Biology. Specifically, the manipulation of existing, and the introduction of new protein-protein interactions will allow great advances in bionanotechnology. In nature, protein-protein assemblies mediate many cellular processes and exhibit complex and efficient functions. It is thus rational to assume human-guided biomolecular assemblies could embody equally complex functionality designed to address current human needs. Here we present the design and prep
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Ruiss, Romana. "Induktion Epstein-Barr Virus-spezifischer Immunantworten durch Exosomen und Virus-like Particles." Diss., lmu, 2010. http://nbn-resolving.de/urn:nbn:de:bvb:19-119153.

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Mažeikė, Eglė. "Generation of anticancer vaccine based on virus-like particles." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2011. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2011~D_20110621_164205-79199.

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In this dissertation the investigation of potential applications of hamster polyomavirus (HaPyV) major capsid protein VP1 based chimeric virus-like particles (VLPs) harboring CTL epitopes for anticancer vaccine development is presented. The objective of this study was to investigate the potential of recombinant HaPyV VP1 based VLPs for anticancer vaccine generation in model systems, including investigation of VP1 applicability for heterologous CTL epitopes insertions, VLPs assembly and ability to induce insert specific immune response in vivo. HaPyV VP1 VLPs carrying CLT epitopes derived from
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Zhang, Naru, and 张娜茹. "Study on influenza virus-like particles and ssDNA aptamers." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/200167.

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Since there is an urgent need for development of vaccines and antiviral agents to combat influenza pandemics, this study aimed to develop influenza virus-like particles (VLPs) and aptamers targeting the virus particles as vaccine and antiviral agent candidates. Influenza VLPs containing three structural proteins of hemagglutinin (HA), neuraminidase (NA) and matrix 1 (M1) derived from influenza A/Hong Kong/01/2009 (H1N1) virus (HK/01) were constructed using a Bac-to-Bac baculovirus expression system. The expressed VLPs were purified by sucrose density gradient ultracentrifugation and characte
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Hanslip, Simon John. "Production and assembly of human papillomavirus virus-like particles." Thesis, University of Cambridge, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.614258.

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Överby, Anna K. "Uukuniemi virus-like particles : a model system for bunyaviral assembly /." Stockholm, 2007. http://diss.kib.ki.se/2007/978-91-7357-238-5/.

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Venkatesh, Murthy Ambika Mosale. "Virus-like particles as a vaccine against porcine reproductive and respiratory syndrome virus." Thesis, Virginia Tech, 2013. http://hdl.handle.net/10919/50974.

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Porcine reproductive and respiratory syndrome (PRRS) is the most significant infectious disease currently affecting the swine industry worldwide. Several inactivated and modified live vaccines (MLV) have been developed to curb PRRSV infections. The unsatisfactory efficacy and safety of these vaccines, drives for the development of new generation PRRS universal vaccines. Virus like particles (VLPs) based vaccines are gaining increasing acceptance compared to subunit vaccines, as they present the antigens in more veritable conformation and are even readily recognized by the immune system. Hepati
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Keller, Susanne Anita. "Cross-presentation of and cross-priming by virus-like particles /." [S.l.] : [s.n.], 2009. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=18320.

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González, Domínguez Irene. "Characterization and purification of HIV-1 based virus-like particles." Doctoral thesis, Universitat Autònoma de Barcelona, 2020. http://hdl.handle.net/10803/670546.

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Les virus-like particles (VLPs) de VIH han sorgit com una prometedora alternativa per al desenvolupament de nous candidats vacunals, però també per al disseny de teràpies avançades en el camp de la nanomedicina. En els últims anys, s’han desenvolupat diferents estratègies d’optimització per la producció de VLPs de VIH en cultius de cèl·lules animals. Malgrat aquests avanços, la manca d’informació sobre el procés de producció de les VLPs a nivell intracel·lular, la necessitat de mètodes analítics adients per la quantificació de les VLPs de VIH i la seua diferenciació d’altres estructures vesicu
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Roth, Jeanne-Francoise. "Regulation and assembly of the yeast Ty1 virus like particles." Thesis, University of Oxford, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301254.

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Books on the topic "Empty virus like particles"

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Pumpens, Paul, and Peter Pushko. Virus-Like Particles: A Comprehensive Guide. Taylor & Francis Group, 2022.

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Pumpens, Paul, and Peter Pushko. Virus-Like Particles: A Comprehensive Guide. Taylor & Francis Group, 2022.

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Pumpens, Paul, and Peter Pushko. Virus-Like Particles: A Comprehensive Guide. Taylor & Francis Group, 2022.

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Virus-Like Particles: A Comprehensive Guide. Taylor & Francis Group, 2022.

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Virus-Like Particles: A Comprehensive Guide. CRC Press LLC, 2022.

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Jegerlehner, Andrea. Vaccination strategy based on virus-like particles. 2003.

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Chikungunya Virus-Like Particles As Vaccine Candidates: A Pilot Study. Arcler Education Inc, 2022.

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Chikungunya Virus-Like Particles As Vaccine Candidates: A Pilot Study. Arcler Education Inc, 2023.

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Storni, Tazio. Induction of T cell responses with virus-like particles: Combining adaptive and innate immunity for optimal efficacy. 2003.

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Lipson, Manuel Jacob. Response of Virus-Like Particles in Ehrlich Ascites Tumor Cells to Several Pharmacological Agents As Seen with the Electron Microscope. Creative Media Partners, LLC, 2021.

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Book chapters on the topic "Empty virus like particles"

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Sainsbury, Frank, Pooja Saxena, Alaa A. A. Aljabali, Keith Saunders, David J. Evans, and George P. Lomonossoff. "Genetic Engineering and Characterization of Cowpea Mosaic Virus Empty Virus-Like Particles." In Methods in Molecular Biology. Humana Press, 2013. http://dx.doi.org/10.1007/978-1-62703-751-8_11.

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Mehlhorn, Heinz. "Virus like Particles." In Encyclopedia of Parasitology. Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-43978-4_4387.

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Mehlhorn, Heinz. "Virus-like Particles." In Encyclopedia of Parasitology. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-27769-6_4387-1.

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Nooraei, Saghi, Howra Bahrulolum, Camellia Katalani, Mohsen Bidar Ajorloo, Gholamreza Ahmadian, and Abbas Hajizade. "Virus-like Particles." In Microbiology in the Era of Artificial Intelligence. CRC Press, 2025. https://doi.org/10.1201/9781003410164-5.

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Pumpens, Paul, Peter Pushko, and Philippe Le Mercier. "Order Rowavirales." In Virus-Like Particles. CRC Press, 2022. http://dx.doi.org/10.1201/b22819-6.

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Pumpens, Paul, Peter Pushko, and Philippe Le Mercier. "Order Cirlivirales." In Virus-Like Particles. CRC Press, 2022. http://dx.doi.org/10.1201/b22819-13.

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Pumpens, Paul, Peter Pushko, and Philippe Le Mercier. "Order Piccovirales." In Virus-Like Particles. CRC Press, 2022. http://dx.doi.org/10.1201/b22819-12.

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Pumpens, Paul, Peter Pushko, and Philippe Le Mercier. "Order Tymovirales." In Virus-Like Particles. CRC Press, 2022. http://dx.doi.org/10.1201/b22819-26.

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Pumpens, Paul, Peter Pushko, and Philippe Le Mercier. "Order Bunyavirales." In Virus-Like Particles. CRC Press, 2022. http://dx.doi.org/10.1201/b22819-38.

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Pumpens, Paul, Peter Pushko, and Philippe Le Mercier. "Prologue." In Virus-Like Particles. CRC Press, 2022. http://dx.doi.org/10.1201/b22819-1.

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Conference papers on the topic "Empty virus like particles"

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Dragnea, Bogdan. "Superfluorescent Virus-like Particles." In Novel Optical Materials and Applications. OSA, 2021. http://dx.doi.org/10.1364/noma.2021.now1d.3.

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Liu, Qiang-Qiang, and Ming-Lian Wang. "The Current Status of Virus-like Particles." In 2015 International Conference on Medicine and Biopharmaceutical. WORLD SCIENTIFIC, 2016. http://dx.doi.org/10.1142/9789814719810_0036.

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Fan, X. Z., L. Naves, N. P. Siwak, A. Brown, J. Culver, and R. Ghodssi. "VIRUS-LIKE-PARTICLES FOR NEXT GENERATION MICRO/NANO-BIOSENSORS." In 2014 Solid-State, Actuators, and Microsystems Workshop. Transducer Research Foundation, 2014. http://dx.doi.org/10.31438/trf.hh2014.125.

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Cheng, Xing-Jian, Yan-Ling Wu, Yoshimasa Tanaka, and Wen Zhang. "expression of norovirus virus-like particles in different systems." In 2014 International Conference on Computer Science and Electronic Technology. Atlantis Press, 2015. http://dx.doi.org/10.2991/iccset-14.2015.118.

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Lin, Shih-Yeh, Cheng-Yu Chung, Yao-Chi Chung, Hsin-Yi Chiu, and Yu-Chen Hu. "Development of Enterovirus 71 Vaccine based on Virus-like Particles." In 14th Asia Pacific Confederation of Chemical Engineering Congress. Research Publishing Services, 2012. http://dx.doi.org/10.3850/978-981-07-1445-1_411.

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Feizpour, A., and B. M. Reinhard. "Approximating the Concentration of Lipids on the Surface of Virus-Like Particles through Plasmon Coupling." In CLEO: Applications and Technology. OSA, 2014. http://dx.doi.org/10.1364/cleo_at.2014.am2p.3.

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Trashi, Orikeda, and Orikeda. "1147 Bioengineered virus-like particles as novel immunotherapy: enhancing T cell recruitment in cancer treatment." In SITC 39th Annual Meeting (SITC 2024) Abstracts. BMJ Publishing Group Ltd, 2024. http://dx.doi.org/10.1136/jitc-2024-sitc2024.1147.

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Govind, Shubha. "Molecular analysis of immune-suppressive virus-like particles from cynipid waspLeptopilinaheterotoma,a generalist parasite ofDrosophila spp." In 2016 International Congress of Entomology. Entomological Society of America, 2016. http://dx.doi.org/10.1603/ice.2016.92691.

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Lemke, Caitlin, Aliasger Salem, Arthur Krieg, and George Weiner. "Abstract 1417: Combination cancer immunotherapy using checkpoint blockade and intratumoral virus-like particles containing CpG ODN." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-1417.

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Trashi, Ikeda, and Jeremiah Gassensmith. "1334 Employing bioengineered virus-like particles: innovative strategies for targeting tumors, suppressing growth, and preventing metastasis." In SITC 39th Annual Meeting (SITC 2024) Abstracts. BMJ Publishing Group Ltd, 2024. http://dx.doi.org/10.1136/jitc-2024-sitc2024.1334.

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Reports on the topic "Empty virus like particles"

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Erdman, Matthew M., Brenda G. Crabtree, D. L. Hank Harris, and Kurt I. Kamrud. Immunization of Swine with Virus-like Replicon Particles: Proof of Concept. Iowa State University, 2007. http://dx.doi.org/10.31274/ans_air-180814-19.

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Bacharach, Eran, W. Ian Lipkin, and Avigdor Eldar. Identification of the etiological agent of tilapia disease in the Lake of Galillee. United States Department of Agriculture, 2013. http://dx.doi.org/10.32747/2013.7597932.bard.

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Background to the topic. Tilapines serve as the second most important group of farmed fish worldwide. Massive mortality of wild and cultured tilapia has been observed recently in Israel but the pathogen of this disease has not been identified. We proposed to identify the agent responsible for disease.  Major conclusions, solutions, achievements. We characterized the lesions in diseased fish and found that the brain was one of the affected organs. We found conditions to isolate from brains of diseased fish the etiological agent of the tilapia disease and to propagate it in cell culture. This l
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Vakharia, Vikram, Shoshana Arad, Yonathan Zohar, Yacob Weinstein, Shamila Yusuff, and Arun Ammayappan. Development of Fish Edible Vaccines on the Yeast and Redmicroalgae Platforms. United States Department of Agriculture, 2013. http://dx.doi.org/10.32747/2013.7699839.bard.

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Betanodaviruses are causative agents of viral nervous necrosis (VNN), a devastating disease of cultured marine fish worldwide. Betanodavirus (BTN) genome is composed of two single-stranded, positive-sense RNA molecules. The larger genomic segment, RNA1 (3.1 kb), encodes the RNA-dependent RNA polymerase, while the smaller genomic segment, RNA 2 (1.4kb), encodes the coat protein. This structural protein is the host-protective antigen of VNN which assembles to form virus-like particles (VLPs). BTNs are classified into four genotypes, designated red-spotted grouper nervous necrosis virus (RGNNV),
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