Academic literature on the topic 'Emulsion solvent diffusion method'

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Journal articles on the topic "Emulsion solvent diffusion method"

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Zhang, Zhi-Bing, Zhi-Gang Shen, Jie-Xin Wang, et al. "Micronization of silybin by the emulsion solvent diffusion method." International Journal of Pharmaceutics 376, no. 1-2 (2009): 116–22. http://dx.doi.org/10.1016/j.ijpharm.2009.04.028.

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THAKUR, PURSHOTTAM KUMAR, C. K. TYAGI, and NEELESH CHOUBEY. "FORMULATION AND EVALUATION OF GASTRO-RETENTIVE MICROSPHERE OF SAXAGLIPTIN ANTIDIABETIC AGENT." Current Research in Pharmaceutical Sciences 13, no. 3 (2023): 126–32. http://dx.doi.org/10.24092/crps.2023.130302.

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The objective of this study was to develop a gastro-retentive microsphere of Saxagliptin. Saxagliptin is an orally active hypoglycemic drug of the newdipeptidylpeptidase-4(DPP4) inhibitor class of drug. Nine formulations of Saxagliptin microsphere are prepared by Emulsion solvent diffusion method using polymers like Eudragit RS 100 and Ethyl cellulose at different drug to polymer ratios and Polyvinyl Alcohol as Stabilizing agent by Emulsion Solvent Diffusion Method. The formulations were optimized on the basis of percent buoyancy and in vitro drug release. The prepared microspheres were evalua
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Thenge, R. R., M. P. Chandak, and V. S. Adhao. "Spherical Crystallization: A Tool to Improve the Physicochemical Properties of APIs." Asian Journal of Pharmaceutical Research and Development 8, no. 3 (2020): 104–10. http://dx.doi.org/10.22270/ajprd.v8i3.727.

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A greater challenge in solid dosage formulation is the development of spherical agglomerates which increases the solubility and bioavailability of the drug. Spherical crystallization is “An agglomeration process that transforms crystals directly into compact spherical forms during the crystallization process.” Spherical crystallization is the novel agglomeration technique that can transform directly the fine crystals produced in the crystallization process into a spherical shape. Direct Compression of powders is simple and easy way of making tablets. In direct compression of Good Compressibili
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Faten Q. Ibraheem and Anmar A. Abdelrazzaq. "Studying the effect of variables on baclofen floating microsponge." International Journal of Research in Pharmaceutical Sciences 10, no. 3 (2019): 1300–1306. http://dx.doi.org/10.26452/ijrps.v10i3.1467.

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The aim of the present work was to develop a microsponge delivery system of baclofen to control its release and thereby reducing dosing frequency and enhancing patient compliance. The microsponge was produced by oil in oil emulsion solvent diffusion method. The effects of drug/polymer ratio, stirring time and type of Eudragit polymer on the physical characteristics of microsponges were investigated. The prepared microsponges was characterized for production yield (PY), loading efficiency (LD), particle size, surface morphology, and in vitro drug release. The results showed that the microsponge
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Srivastava, Saloni, Supriyo Saha, and Vikash Jakhmola. "Nanogel: Types, Methods of Preparation, Limitation, Evaluation and Application – A Systematic Review." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 13, no. 04 (2023): 1631–39. http://dx.doi.org/10.25258/ijddt.13.4.77.

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Nanogels combine the characteristics of nanomaterials with hydrogels. To meet the expanding demands from various areas, a sizable number of nanogels have been designed and manufactured using the emulsion solvent diffusion nano precipitated method, emulsion evaporation of the solvent method, reverse micellar method and modified diffusion emulsification method. Thermosensitive nanogel, pH-sensitive nanogel, ultrasound-sensitive magnetic response, response to multiple stimuli, chain transfer polymerization, photo-induced crosslinking polymerization and modifications for active targeting are the t
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Anisyabana, Ninda, Anni Anggraeni, Uji Pratomo, and Riska Anbar Fadiyah. "Effect of Different Types of Extractants in the Separation of Rare Earth Metals using Emulsion Liquid Membrane Method: A Review." Jurnal Akademika Kimia 10, no. 2 (2021): 105–18. http://dx.doi.org/10.22487/j24775185.2021.v10.i2.pp105-118.

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Rare Earth Metals (REMs) are minerals which needed in modern technology because it has unique chemical, catalytic, electrical and paramagnetic properties, so REMs have the potential to be applied in various fields. The similarity in the physical and chemical properties of REMs causes them to be difficult to separate from their parent minerals. Emulsion Liquid Membrane is an effective and efficient method for REMs purification and separation because in practice it only requires a small amount of solvent, the diffusion rate and mass transfer are high, fast, and simultaneous compared to the solve
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Maghsoodi, Maryam, and Ali Nokhodchi. "Agglomeration of celecoxib by quasi-emulsion solvent diffusion method without stabilizer: effect of good solvent." Pharmaceutical Development and Technology 23, no. 10 (2017): 1037–46. http://dx.doi.org/10.1080/10837450.2016.1270965.

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Kawashima, Y., T. Iwamoto, T. Niwa, H. Takeuchi, and T. Hino. "Role of the solvent-diffusion-rate modifier in a new emulsion solvent diffusion method for preparation of ketoprofen microspheres." Journal of Microencapsulation 10, no. 3 (1993): 329–40. http://dx.doi.org/10.3109/02652049309031523.

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Tyagi, Gajendra, and Suresh Choudhary. "Preparation of flutrimazole micro sponge gel by quasi-emulsion solvent diffusion method." Asian Journal of Pharmaceutical Research and Development 12, no. 3 (2024): 43–49. http://dx.doi.org/10.22270/ajprd.v11i3.1393.

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Microsponge containing Flutrimazole drug with six different proportions of Eudragit RS 100 as polymer were obtained successfully using quasi-emulsion solvent diffusion method. Particle size and physical properties of the formulations were examined. Physical properties showed that microsponge formulations MS IV and MS VI exhibited better material efficiency and yield. Two microsponge formulations were prepared as gels in 0.35% w/w carbomer and examined for pH, viscosity, permeability, drug content, in vitro release, antibacterial activity, and in vivo antifungal activity on Rabbit skin. The vis
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Maghsoodi, Maryam, and Ali Nokhodchi. "Agglomeration of Celecoxib by Quasi Emulsion Solvent Diffusion Method: Effect of Stabilizer." Advanced Pharmaceutical Bulletin 6, no. 4 (2016): 607–16. http://dx.doi.org/10.15171/apb.2016.075.

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Dissertations / Theses on the topic "Emulsion solvent diffusion method"

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Nabar, Gauri M. "Encapsulation of nanoparticles and polymers within block copolymer micelles prepared by the emulsion and solvent evaporation method." The Ohio State University, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=osu1503199514997833.

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Eser, Hülya Tıhmınlıoğlu Funda. "Diffusion And Equilibrium Measurements In Polymer-Solvent Systems By Inverse Gas Chromatography Method/." [s.l.]: [s.n.], 2004. http://library.iyte.edu.tr/tezler/master/kimya/T000451.pdf.

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Charabudla, Yamuna Reddy. "PROCESS FOR FORMATION OF CATIONIC POLY (LACTIC-CO-GLYCOLIC ACID) NANOPARTICLES USING STATIC MIXERS." UKnowledge, 2008. http://uknowledge.uky.edu/gradschool_theses/580.

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Nanoparticles have received special attention over past few years as potential drug carriers for proteins/peptides and genes. Biodegradable polymeric poly (lactic-co-glycolic acid) (PLGA) nanoparticles are being employed as non-viral gene delivery systems for DNA. This work demonstrates a scalable technology for synthesis of nanoparticles capable of gene delivery. Cationic PLGA nanoparticles are produced by emulsiondiffusion- evaporation technique employing polyvinyl alcohol (PVA) as stabilizer and chitosan chloride for surface modification. A sonicator is used for the emulsion step and a stat
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Nastiti, Christofori Maria Ratna Rini. "Development and evaluation of polymeric nanoparticle formulations for triamcinolone acetonide delivery." Thesis, Curtin University, 2007. http://hdl.handle.net/20.500.11937/613.

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The aims of this study were to develop polymeric NP formulations for triamcinolone acetonide (TA) delivery, from biodegradable and biocompatible hydrophobic polymers, which provide sustained release, prolonged stability and low toxicity, and to assess the toxicity of TA NPs (TA-NPs) compared to TA alone upon BALB/c 3T3 and ARPE 19 cell culture models.The study involved investigation of three different types of polymers: poly(D,L,lactide) (PDLLA), poly(D,L,lactide-co-glycolide)(PLGA) and methoxypolyethyleneglycol poly(D,L,lactide-co-glycolide)(mPEG PLGA). Two different methods were studied in t
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Wu, Giin-Wen, and 吳錦文. "Conurolled Release Drug Microcapsules Prepared by Emulsion Solvent Evaporation Method." Thesis, 1996. http://ndltd.ncl.edu.tw/handle/68030634689056097526.

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碩士<br>國立成功大學<br>化學工程學系<br>84<br>The emulsion solvent evaporation method was used to prepare controlled rele-ase formation of drugs in this report. The microcapsules of controlled relea-se was formed by polymer solution (Ethylcellulose) containing drug (Aspirin). There were six variables, including the addition nonsolvent volume in coat-ing solution, the different polymer concertration, the different ratio of drugto shell , the different ratio of dispersion medium volume to solvent volu
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Kun, Peng Jui, and 彭瑞坤. "Studies on the properties of ethylcellulose microcapsules prepared by emulsion non-solvent addition method." Thesis, 1995. http://ndltd.ncl.edu.tw/handle/25369341966233690024.

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碩士<br>國立中央大學<br>化學工程研究所<br>83<br>The preparation of ethylcellulose microcapsules containingheophylline by using o/w emulsion nonsolvent-addition phaseeparation method was developed. Dichloromethane-n-hexane werehosen as solvent-nonsolvent system. The first stage of this workas to determine the process of drug loss. In the second stage ofhis work, some methods were proposed to reduce drug loss. Theharacteristics of microcapsules prepared by these methods werenvestigated. The results indicate
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Chang, Chia-Ju, and 張加儒. "Microencapsulation of epoxy curing agent by oil-in-water emulsion and solvent evaporation method." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/zc29pu.

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碩士<br>國立臺灣大學<br>高分子科學與工程學研究所<br>106<br>Although epoxy resins have excellent mechanical and chemical properties, epoxy resins and curing agent are generally stored in two pots to prevent unnecessary curing reaction at room temperature. To solve this problem, we developed a one pot system which can be stored for a long time at room temperature by a simple, nontoxic processing. This involves the encapsulation of the curing agent, 2-phenylimidazole (2PhI), in polycaprolactone (PCL) microcapsules fabricated by oil-in-water emulsion and solvent evaporation method with different organic solvents and
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Chang, Liling, and 張麗玲. "Studies on the preparation of ethylcellulose microcapsules by using o/w emulsion solvent evaporation method." Thesis, 1998. http://ndltd.ncl.edu.tw/handle/20176669638720178853.

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碩士<br>國立中央大學<br>化學工程學系<br>86<br>The microcapsules containing water-soluble drug prepared by using O/Wemulsion solvent evaporation method in order to reduce the additiond ofsolvent wrer developed. Microencapsulation condition, system temperature,polymer concentration, co-solvent on drug loss, particle size, surface morphology and release rate of microcapsules were disscussed.
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Hsiung, Chia-Cheng, and 熊家正. "Preparation and release behaviour of ethylcellulose microcap- ules by using emulsion non-solvent addition method." Thesis, 1994. http://ndltd.ncl.edu.tw/handle/33254611421249441547.

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Loon, Chang Chen, and 張正倫. "Studies on the preparation of EC/CTA microcapsule by using emulsion non-solvent addition method." Thesis, 1993. http://ndltd.ncl.edu.tw/handle/31695483765278526659.

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Book chapters on the topic "Emulsion solvent diffusion method"

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Avgerinos, A. "Controlled Release Microspheres Prepared by using an Emulsion Solvent-Diffusion Technique as a Tool in Design of new Antidotes." In NBC Risks Current Capabilities and Future Perspectives for Protection. Springer Netherlands, 1999. http://dx.doi.org/10.1007/978-94-011-4641-8_32.

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Aishwarya, KVNR, and Praveen Sivadasu. "Preparation of Rilpivirine Nanosponges Using Different Methodologies." In Current Trends in Drug Discovery, Development and Delivery (CTD4-2022). Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671090-00611.

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Rilpivirine is an analogue of a nucleoside that inhibits reverse transcriptase. Various polymers including ethyl cellulose (EC), -cyclodextrin (-CD), polyvinyl alcohol (PVA), polyvinyl pyrrolidone K-30 (PVP K-30), cross-linkers including dichloromethane (DCM), dimethyl carbonate (DMC), glutaraldehyde (GTLD), stabilisers including kondagogu gum (kgg), olibanum gum (OLG), and solvents like ethanol, methanol, dimethyl sulfoxide (DMSO), dimethyl formamide (DMF), dist. water etc were used with different proportion with respective methods of preparation. Emulsion Ultrasonic-assisted synthesis, solve
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R., Amit, Pravin S., and Dinesh M. "Preparation of Carvedilol Spherical Crystals Having Solid Dispersion Structure by the Emulsion Solvent Diffusion Method and Evaluation of Its in vitro Characteristics." In Advances in Crystallization Processes. InTech, 2012. http://dx.doi.org/10.5772/45805.

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Zhang, Xiaoming, Wenwen Deng, and Jing Wang. "Preparation and Characteristic of Waterborne Acrylate Adhesive." In Proceedings of the 2022 International Conference on Smart Manufacturing and Material Processing (SMMP2022). IOS Press, 2022. http://dx.doi.org/10.3233/atde220836.

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Aqueous emulsion acrylic adhesive was prepared by batch emulsion polymerization With 2-ethylhexyl acrylate (2-EHA) and butyl acrylate (BA) as soft monomers, methyl methacrylate (MMA) as hard monomer, acrylic acid (AA), acrylic amide (AM) and hydroxyethyl acrylate (HEA) as hydrophilic functional monomers, dodecanethiol (NDM) as molecular weight regulator, Sodium dodecyl benzene sulfonate (SDBS) and octyl phenol polyoxyethylene ether (op-10) as mixed emulsifiers, ammonium persulfate (APS) as initiator, and distilled water (H2O) as solvent. The effects of monomer, emulsifier, initiator, reaction
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M N, Madhavi, Pankaj M. Pimpalshende, Satish B. Kosalge, Shubhangi M. Kaurase, and Rajashree V. Lode. "A NOVEL APPROACH TO DRUG DELIVERY SYSTEMS: MICROSPONGES." In Futuristic Trends in Pharmacy & Nursing Volume 3 Book 16. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3bkpn16p2ch2.

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To maximize therapeutic efficacy and cost-effectiveness, innovative drug delivery technology has developed intensely competitive and is growing quickly. Microsponges are one of these cutting-edge developing techniques for precise, controlled, and target-specific medication administration. Microsponges are microscopic polymeric particles with porous surfaces resembling sponges, and pore ranges in size from 5 to 300 microns. The microsponge system can be made into gel, ointment, creams, liquids, or powders with good efficiency. More recently, it has been made into tablets and capsules for oral d
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Filippa, Mauricio. "Physical Pharmacy." In Advanced Pharmacy. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/9789815049428123010003.

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In this chapter, we focus on solutions. In the introduction, general and descriptive aspects are defined, such as the classification of solutions and the addition of solids. Considering the properties of these systems, we focus on definitions related to colligative properties, and on the use of this property for the adjustment of isotonic solutions considering the selective capacity of the membranes, differentiation of tonicity and osmolarity. We also introduce the calculations necessary for the preparation of isotonic solutions with blood plasma, using the mass and volume adjustment method. T
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Srikar, Grandhi, and I. Nagamma. "Quality by Design Approach for Optimization and Development of Gastro-Retentive Hollow Microspheres for Prasugrel." In Current Trends in Drug Discovery, Development and Delivery (CTD4-2022). Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671090-00414.

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Prasugrel (PSG) is used in minimizing the risk of atherothrombotic events in people with cardiovascular problems. Developing extended-release products for PSG is highly advantageous owing to its pharmacodynamic and pharmacokinetic properties. But, due to its insolubility in aqueous media with pH above 6.0, it becomes poorly bioavailable from the small intestine upon oral administration. Hence, an extended-release formulation which resides in gastric region until released completely is highly recommended. Polymeric hollow-microspheres with inherent floating property without lag time are highly
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Turchetti, Giovanni, and Diana De Santis. "Hydrolates: Characteristics, Properties, and Potential Uses in the Food Industry." In New Findings from Natural Substances. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9789815051421122010011.

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Hydrodistillation is a traditional method that has long been used to extract essential oils and hydrolates from plant matrices known to be rich in bioactive compounds. The use of water as a solvent in the process does not require the recovery of the solvent, with a saving in terms of time, energy, loss of volatile compounds, and a lower environmental impact. Very often, and for some matrices rich in essential oils, hydrolates are considered a by-product. They contain a variety of organic phytochemicals which can be extracted and used for other medicinal, cosmetic, dermatological, and commercia
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Shirode, Devendra S., Vaibhav R. Vaidya, and Shilpa P. Chaudhari. "Computational Tools to Predict Drug Release Kinetics in Solid Oral Dosage Forms." In Software and Programming Tools in Pharmaceutical Research. BENTHAM SCIENCE PUBLISHERS, 2024. http://dx.doi.org/10.2174/9789815223019124010013.

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Dissolution is the concentration of a drug that goes into solution per unit of time under standard conditions of solid-liquid interface, temperature, and composition of solvent. In the pharmaceutical industry, in vitro dissolution testing has been established as a preferred method to evaluate the development potential of new APIs and drug formulations and to select the most appropriate solid form for further development. Dissolution allows the measurement of some important physical parameters, like drug diffusion coefficient, and is also used in model fitting on experimental release data. Kine
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Brisson, A., and O. Lambert. "Two-Dimensional Crystallization of Soluble Proteins on Planar Lipid Films." In Crystallization of Nucleic Acids and Proteins. Oxford University Press, 1999. http://dx.doi.org/10.1093/oso/9780199636792.003.0016.

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Electron crystallography of protein two-dimensional (2D) crystals constitutes a fast-expanding method for determining the structure of macromolecules at near-atomic resolution (1, 2). The main limitation in the application and generalization of this approach remains in obtaining highly ordered 2D crystals, as is the case of 3D crystals in X-ray crystallography. Several methods of 2D crystallization are available which can be classified into two families, depending on the type of proteins under investigation, either membrane proteins (3, 4) or soluble proteins (5, 6). In both cases, 2D crystall
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Conference papers on the topic "Emulsion solvent diffusion method"

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Mathews, Tanya Ann, Alex J.Cortes, Richard Bryant, and Berna Hascakir. "Miscible Flooding for Bitumen Recovery with a Novel Solvent." In SPE Annual Technical Conference and Exhibition. SPE, 2021. http://dx.doi.org/10.2118/206325-ms.

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Abstract Steam injection is an effective heavy oil recovery method, however, poses several environmental concerns. Solvent injection methods are introduced in an attempt to combat these environmental concerns. This paper evaluates the effectiveness of a new solvent (VisRed) in the recovery of a Canadian bitumen and compares its results with toluene. While VisRed is selected due to its high effectiveness as a viscosity reducer even at very low concentrations, toluene is selected due to its high solvent power. Five core flooding experiments were conducted; E1 (Steam flooding), E2 (VisRed floodin
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Mathews, Tanya Ann, Paul Azzu, Jairo Cortes, and Berna Hascakir. "Effective Extraction of a Heavy Oil Resource by an Environmentally Friendly Green Solvent: Limonene." In SPE Annual Technical Conference and Exhibition. SPE, 2022. http://dx.doi.org/10.2118/210138-ms.

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Abstract Global oil consumption is predicted to increase by 15% from 2021 to 2050. The increasing oil demand and decreasing conventional oil supply force us to find alternate energy supplies. The key to this problem lies with the vast untapped heavy oil and bitumen resources. In this study, we investigate the effectiveness of an environmentally friendly solvent, limonene, in recovering heavy oil. Three core flood experiments representing three different recovery methods were carried out. These include steam flooding (E1), solvent flooding (E2), and solvent-steam co-injections (E3). The green s
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Ma, Ming, and Hamid Emami-Meybodi. "Diffusion-Based Multiphase Multicomponent Modeling of Cyclic Solvent Injection in Ultratight Reservoirs." In SPE Annual Technical Conference and Exhibition. SPE, 2022. http://dx.doi.org/10.2118/210480-ms.

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Abstract The cyclic solvent (gas) injection has been proved as an economical and effective method to enhance oil recovery in ultratight reservoirs such as shales. However, accurate modeling of cyclic solvent injection has been challenging due to the complex nature of fluid transport in nanopores. Most models are developed based on Darcy's and Fick's laws, which do not capture some critical transport phenomena within nanopores at elevated pressure. Accordingly, we propose a predictive model encapsulating the essential transport mechanisms for cyclic solvent injection in ultratight reservoirs. T
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Wang, Baoguo, David A. Weitz, and Ho Cheung Shum. "Tunable Morphology of Monodisperse Polymer Particles With Microfluidics." In ASME 2011 9th International Conference on Nanochannels, Microchannels, and Minichannels. ASMEDC, 2011. http://dx.doi.org/10.1115/icnmm2011-58119.

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In this work, we propose a novel method to fabricate polymer particles with controlled morphology in microchannel by solidification of polymer solutions and study the transition in the shape of these particles from spheres, to cups, and to donuts. The non-spherical geometries are achieved through nonuniform diffusion of the solvent, leading to non-uniform solidification. By adjusting the flow rates of both continuous and dispersed phases, the spatial heterogeneity in the solvent diffusion rate and thus the morphology of the final polymer particles can be tuned. This approach offers a one-step
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Rosanel, Morales. "Novel Multi-Functional Chemistry to Maximize Performance in Paraffin Coated Acid Soluble Scale Cleanups." In ADIPEC. SPE, 2023. http://dx.doi.org/10.2118/216447-ms.

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Abstract Gradual diminution of the flow path of hydrocarbon in the near-wellbore area is actively linked to formation damage accumulation and a reduction in well productivity. Organic deposition in the formation and wellbore area can result from the use of hydrochloric acid (HCl) during acidizing, especially in the presence of free iron and organic liquids such as diesel, kerosene, or gasoline. Laboratory evaluation of the nature of the crude oil and stimulation fluids indicates the potential severity of the problem. This test is called acid sludge test. Utilization of inorganic acid like HCl
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Wamocha, H. L., R. Asmatulu, and T. S. Ravigururajan. "Hydrodynamic Behavior of Magnetic Nanocomposite Spheres Under Magnetic Fields." In ASME 2011 International Mechanical Engineering Congress and Exposition. ASMEDC, 2011. http://dx.doi.org/10.1115/imece2011-62762.

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In the present study, drug carrying magnetic nanocomposite spheres were fabricated using oil-in-oil emulsion/solvent evaporation method and characterized via different techniques. The spheres with a diameter of 200 nm and 3 μm consist of poly (lactic-co-glycolic acid) (PLGA), a drug and magnetic nanoparticles (e.g., Fe3O4 or Co0.5Zn0.5Fe2O4). The spheres were initially dispersed in both deionized (DI) water and viscous glycerol solutions, and pumped in a magnetic field at different tube diameters, pump speeds and concentrations to study the hydrodynamic behavior of drug-carrying magnetic nanoc
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Chen, Yongjie, Yunhan Wang, Xuefei Zou, Tao Liu, Wei Liu, and Jianfeng Xiao. "Productivity Prediction Model of CO2 Huff - N – Puff in Heavy Oil Reservoirs Under Variable Diffusion Coefficient." In 57th U.S. Rock Mechanics/Geomechanics Symposium. ARMA, 2023. http://dx.doi.org/10.56952/arma-2023-0661.

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ABSTRACT CO2 huff − n − puff is considered to be an effective method to improve the recovery efficiency of heavy oil reservoirs, but the solvent-assisted CO2 huff − n − puff productivity prediction mathematical model of horizontal wells in heavy oil reservoirs has not been thoroughly investigated. In this study, we propose an improved model to investigate the CO2 concentration distribution and single horizontal well productivity of heavy oil produced by the solvent-assisted CO2 huff − n − puff technology. Firstly, we establish a multi-region diffusion model based on the variable diffusion coef
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Asmatulu, R., A. Garikapati, H. E. Misak, Z. Song, S. Y. Yang, and P. Wooley. "Cytotoxicity of Magnetic Nanocomposite Spheres for Possible Drug Delivery Systems." In ASME 2010 International Mechanical Engineering Congress and Exposition. ASMEDC, 2010. http://dx.doi.org/10.1115/imece2010-40269.

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Cytotoxicity test is a rapid and standardized in vitro method to determine the harmful effects of materials used for biomedical purposes, such as drug carriers, implants and their coatings, biosensors and surgical/medical devices. In the present study, sol-gel driven nickel ferrite (NiFe2O4) and cobalt ferrite (CoFe2O4) nanoparticles (10–25 nm) at different concentrations were incorporated into biodegradable polymer, poly(lactic-co-glycolic acid) (PLGA), using oil-in-oil emulsion/solvent evaporation technique, and then the cytotoxicity of magnetic nanocomposite spheres was characterized using
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Zhao, Wenyu, Shikai Yang, and Daoyong Yang. "Determination of Dispersion Coefficient of Solvent in Heavy Oil/Bitumen Under Reservoir Conditions." In SPE Annual Technical Conference and Exhibition. SPE, 2024. http://dx.doi.org/10.2118/220762-ms.

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Abstract In this work, the dispersion coefficient of solvent in heavy oil/bitumen is innovatively determined by employing an inverse approach to accurately reproduce the measured temperature, pressure, and production profiles in a heated vapour extraction (H-VAPEX) process, thereby significantly advancing our insights into the dispersion physics under reservoir conditions. Monitoring and surveillance data, including temperature profiles, solvent injection rates, and fluid production rates, from a large three-dimensional (3D) physical experiment for an H-VAPEX test have been meticulously collec
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Yang, Shikai, and Daoyong Yang. "Integrated Characterization of Expanding-Solvent Steam-Assisted Gravity Drainage (ES-SAGD) Processes by Using a Heat-Penetration Criterion within a Unified, Consistent, and Efficient Framework." In SPE Canadian Energy Technology Conference and Exhibition. SPE, 2024. http://dx.doi.org/10.2118/218051-ms.

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Abstract The hybrid solvent-steam injection (e.g., expanding-solvent steam-assisted gravity drainage (ES-SAGD) is the most promising method to enhance heavy oil recovery (EOR); however, it is a quite a challenge to reproduce the experimental measurements and in-situ observations because of the complicated multiphase flow behaviour resulted from the coupled mass and heat transfer. In this work, an integrated technique has been developed and applied for the first time to dynamically and accurately characterize an ES-SAGD process within a unified, consistent, and efficient framework. By taking th
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