Journal articles: 'End of Days'

1

Krauss, Lawrence M. "End-of-Days Danger." Scientific American 302, no. 3 (March 2010): 34. http://dx.doi.org/10.1038/scientificamerican0310-34.

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Potter, Bruce. "The end of zero days?" Network Security 2005, no. 10 (October 2005): 10–11. http://dx.doi.org/10.1016/s1353-4858(05)70290-7.

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Diggins, Alex. "Always the end of days." New Scientist 246, no. 3280 (May 2020): 29. http://dx.doi.org/10.1016/s0262-4079(20)30859-9.

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Pye, Lucian W., and Maria Hsia Chang. "Falun Gong: The End of Days." Foreign Affairs 83, no. 5 (2004): 183. http://dx.doi.org/10.2307/20034122.

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Handt, Oliva, and Adrian Linacre. "The end of bad hair days." Forensic Science International: Genetics Supplement Series 5 (December 2015): e146-e148. http://dx.doi.org/10.1016/j.fsigss.2015.09.059.

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Shishlin, Vladimir. "Three Days to the End of Recertification." Statutes and Decisions 47, no. 1 (January 1, 2012): 35–37. http://dx.doi.org/10.2753/rsd1061-0014470108.

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Roman, David. "End of days for Communications in print?" Communications of the ACM 54, no. 2 (February 2011): 12. http://dx.doi.org/10.1145/1897816.1936942.

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Wansink, B. "The Days Diets Begin, End, and Work Best." Journal of Nutrition Education and Behavior 44, no. 4 (July 2012): S43. http://dx.doi.org/10.1016/j.jneb.2012.03.093.

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DuBois, Thomas. "Book Review: Falun Gong: The End of Days." China Information 19, no. 1 (March 2005): 129–31. http://dx.doi.org/10.1177/0920203x0501900109.

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O’Neil, Caitlin. "The End of Days at Dave and Busters." Massachusetts Review 61, no. 1 (2020): 126–31. http://dx.doi.org/10.1353/mar.2020.0020.

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Zakovitch, Yair. "David's last and early days." Nordisk Judaistik/Scandinavian Jewish Studies 24, no. 1-2 (September 1, 2003): 37–52. http://dx.doi.org/10.30752/nj.69598.

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This article deals with the beginning and end of David’s life. David’s lonely end, a reflection of his incapacity to love, marks the tragic close to his promising beginnings. The author shows how the stories that introduce David are missing two elements: a birth story and a genealogy. This absence can be explained by the biblical author’s desire to portray David as a male-Cinderella. This missing birth story can perhaps be reconstructed by reading between the lines in 1 Samuel 16–17, but also through the use of post-biblical traditions. Connections between the portrayals of the beginning and the end of David show that no progress has been made between the disappointing and tragic end of Saul and that of David.

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Vauchez, Stéphanie Hennette. "The State of Emergency in France: Days Without End?" European Constitutional Law Review 14, no. 4 (November 21, 2018): 700–720. http://dx.doi.org/10.1017/s1574019618000391.

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State of emergency in France – Historical origins of the legal regime – Ways in which it was adapted and normalised between 2015 and 2017 – Application against rule of law principles and human rights standards – Institutional balance between powers – In-depth study of 700 court decisions – Legal challenges to state of emergency measures – Challenges to judicial scrutiny

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Yan, Zhonghu. "Falun Gong: The End of Days – Maria Hsia Chang." Journal of Chinese Philosophy 33, no. 3 (September 2006): 459–61. http://dx.doi.org/10.1111/j.1540-6253.2006.00373.x.

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Kjaerum, Morten. "Human rights: Early days or coming to an end?" Netherlands Quarterly of Human Rights 36, no. 4 (October 22, 2018): 311–18. http://dx.doi.org/10.1177/0924051918806723.

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The speech addresses how human rights are being challenged and to what extent we are witnessing the end times of human rights. Neo-liberalism and populism coming from different corners converge and contribute to the erosion of human rights as well as rule of law institutions. Attempts to link human rights to one or the other economic theory contribute to lifting human rights away from their status of being universal. Human rights are not there to substitute ideological systems, instead it is a far more limited project. In the latter part of the speech new bottom-up trends pulling in the opposite direction are highlighted. As an outcome of the financial crisis and the growing inequality, a stronger awareness has emerged globally about the negative consequences of corruption and tax evasion on human rights and democratic institutions. Human rights are regaining a momentum and credibility in that space. This is closely linked to the new human rights city movement, where local communities take greater responsibility in realizing human rights for their citizens. Finally, in this part the mainstreaming of human rights in laws and political strategies is addressed together with the concept human rights by design. The speech ends on a forward-looking note recognizing the immense challenges that confronts the liberal democracy and human rights currently, however, also recognizing the depth of human rights in most communities.

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Raw, J. "Are the days of bedrails coming to an end?" Age and Ageing 33, no. 6 (September 22, 2004): 641. http://dx.doi.org/10.1093/ageing/afh192.

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Daniels, Stephen, and Hayden Lorimer. "Until the end of days: narrating landscape and environment." cultural geographies 19, no. 1 (January 2012): 3–9. http://dx.doi.org/10.1177/1474474011432520.

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Hargadon, Annemarie P., Barbara Marie Galligan, Chintan Shah, Iris Chen Zhao, Brian Paciotti, Nathan Fairman, and Quy Tran. "OAMs at the end: The end of the beginning or the beginning of the end?" Journal of Clinical Oncology 34, no. 26_suppl (October 9, 2016): 229. http://dx.doi.org/10.1200/jco.2016.34.26_suppl.229.

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229 Background: In 2001, after three months of review, the FDA approved the oral anticancer agent imatinib, making it the fastest approval in FDA history. Since then, the FDA has approved over 40 oral anti-cancer medications (OAMs) and the number continues to rise, transforming cancer care, improving survival in specific cancers and providing new hope. However, the rapid development of OAMs has produced uncertainty over the best use of these new medications, particularly at the end of life. ASCO guidelines recommend against prescribing intravenous chemotherapy within two weeks of expected death, but no such guidelines have yet been developed for OAMs. We describe one institution’s experience in prescribing OAMs at the end of life. Methods: An interdisciplinary team of pharmacy, oncology and palliative care specialists undertook an IRB-approved retrospective electronic health record review of patients who died between 1/1/2012 and 12/31/2015 and had been on one of seven oral anti-cancer medications (erlotinib, sunitinib, pazopanib, crizotinib, sorafenib, afatinib, regorafenib). From this cohort, descriptors such as diagnosis, stage, prior lines of therapy, ECOG, BMI and albumin were extracted. Results: There were at total of 62 patients who were on at least one of the seven drugs and died during the specified time period. Of these 62 patients, only 2 (3%) had a first prescription for an OAM in the last 30 days of life. Over 90% of the patients that were not prescribed an OAM within 30 days of death were patients with Stage IV disease with a median age of 66 and had an average of 3 prior lines of therapy. Consistent with prognostic models, these patients all had declining albumin, BMI and performance status. Conclusions: Oncologists at this institution rely on prognostic data to gauge when to recommend stopping IV chemotherapy before the last two weeks of life. Extrapolating from ASCO guidelines on the use of IV chemotherapy, these oncologists generally refrain from prescribing OAMs in the last 30 days of life. Unless strong data shows definitive benefit for the use of OAMs, we propose ASCO guidelines recommend not using OAMs during the last two weeks of life.

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Omura, Tomoko, Yasuji Miyakita, Takaki Omura, Makoto Ohno, Masamichi Takahashi, Natsuko Satomi, Kenji Fujimoto, and Yoshitaka Narita. "NQPC-10 END-OF-LIFE PHASE OF GLIOBLASTOMA." Neuro-Oncology Advances 1, Supplement_2 (December 2019): ii31. http://dx.doi.org/10.1093/noajnl/vdz039.140.

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Abstract BACKGROUND Despite aggressive treatment with surgery and chemo-radiation therapy, it is difficult to cure patients with glioblastoma (GBM). The end-of-life (EOL) phase of patients with GBM, and related problems, have not yet been adequately studied. Most cancer patients died in the hospital (84%) in 2017, but the Japanese government has recommended palliative home-care and the number of deaths at home has recently been increasing. This study explores the current situation of EOL care for GBM patients in our hospital. METHODS We retrospectively examined the clinical course and EOL phase of 166 consecutive patients who were treated in our hospital between 2010 and 2017. RESULT In total, 107 patients died; 28 (26%) at home, 25 (23%) in hospice care, 9(9%) in nursing homes, 21(20%) in long-term care hospitals (LTCH), 13(12%) in our hospital, and 11(10%) in other neurosurgical hospitals. The median survival time and length of EOL phase for patients who died at home were 596 and 77 days; 469 and 103 days in hospice care; 528 days and 149 days in LTCH; 388 days and 52 days in our hospital; 802 and 91 days in other neurosurgical hospital; and 565 days and 55 days in nursing homes, respectively. The KPS of patients who transferred to LTCH or was started palliative care in other neurological hospital was 60. That of other patients was 50.The patients who died at home entered deep coma in the last 3.5 days (n=24) of life and could not take oral feeds for 7 days (n=26). CONCLUSION According to cancer patient study, the home-based palliative time of longer prognosis group were 59 days. EOL phase of GBM may be longer than other cancer. We must consider the problems of the EOL phase and improve the quality of EOL care.

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Sterritt, D. "From the Beginning of Time to the End of Days." Tikkun 26, no. 4 (October 1, 2011): 31–32. http://dx.doi.org/10.1215/08879982-2011-4014.

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Pilikian, Vaughan. "Parallel Seizure: Art and Culture at the End of Days." PAJ: A Journal of Performance and Art 43, no. 1 (January 2021): 3–18. http://dx.doi.org/10.1162/pajj_a_00543.

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21

Namireddy, Praveen, Vicki McLawhorn, Sweta Jonnalagadda, and Mahvish Muzaffar. "Equality during end-of-life cancer care: Trends in aggressiveness of cancer care at the end of life." Journal of Clinical Oncology 35, no. 31_suppl (November 1, 2017): 77. http://dx.doi.org/10.1200/jco.2017.35.31_suppl.77.

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77 Background: Aggressive cancer care at the end of life (EOL) can impact quality of life and have major economic burden. The purpose of this study was to portray the aggressiveness of EOL cancer care, and its relation to race, gender and social factors in Eastern North Carolina with high rural and minority population. Methods: This is a retrospective analysis of 401 stage 4 solid tumor patients who died between 2011 and 2014. Aggressiveness of care was calculated by a composite score adopted from Earle et al. Scores range from 0 to 7 with higher scores indicating more aggressive EOL care. 1 point was given to each indicator of aggressiveness in the last 30 days of life: ED visits ≥2,hospital admissions ≥2,any ICU admission,hospitalized days ≥14,new chemotherapy, hospice care ≤ 3 days, and any chemotherapy in the last 14 days. Results: Among the 401 patients, 217 (54%) were white and 178 (44%) were black. The mean composite score of aggressiveness (CSA) for whites was 1.18 and for blacks it was 1.87. (p<0.001).In the last 30 days of death, a higher proportion of blacks had ≥ 2 ED visits 28% vs 13%(p<.0001), ≥ 2 hospital admission 23% vs 13%(p=0.001), any ICU admission 29% vs 16%(p=0.0002), chemotherapy in the last 14 days 30% vs 20%(p=0.001), ≥ 14 hospitalized days 35% vs 21%(p<0.001), and hospital deaths 46% vs 32%(p=0.001) compared to whites. More whites enrolled in hospice compared to blacks 53% vs 45% (p<0.001). Correlation analysis using Fit Y by X model between CSA (score ≤ 3 and >3) and other variables showed statistically significant difference between whites vs blacks p <0.001, females vs males p=0.0006, not married vs married p<0.0001, and no family support vs family support p<0.0001. Conclusions: Male, unmarried and black patients were associated with higher CSA. Patients who were white, married and with family support had high likelihood of enrolling in hospice. [Table: see text]

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22

Huang, Yu Chuan, and Shu Hui Chan. "Trading Behavior on Expiration Days and Quarter-End Days: The Effect of a New Closing Method." Emerging Markets Finance and Trade 46, no. 4 (January 2010): 105–25. http://dx.doi.org/10.2753/ree1540-496x460407.

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23

Henderson, Stuart. "Toronto’s Hippie Disease: End Days in the Yorkville Scene, August 1968." Journal of the Canadian Historical Association 17, no. 1 (July 23, 2007): 205–34. http://dx.doi.org/10.7202/016108ar.

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Abstract In mid-summer, 1968, the idea that the hip Yorkville district represented a pox on the face of Toronto became a kind of reality: Hepatitis appeared to be taking over the scene. Throughout the 1960s, Yorkville had been framed as a neighborhood at risk, a symbolically “sick community” by its many detractors. It had been variously described as a “festering sore” and a “madhouse” by city fathers. But with an apparent Hepatitis epidemic came the opportunity to establish Yorkville as a new variety of illness. Yorkville was no longer figuratively sick, it was now quite literally infected. Throughout the month of August, 1968, Yorkville’s hip youth culture became the lepers of Toronto. Even though when by September all evidence showed that the Hepatitis rate in Yorkville was in no way indicative of an epidemic – all but two of the Villagers tested turned out to be intravenous drug users, signifying that the disease was being spread through dirty needles, not food or water – the damage was done, and Yorkville’s hip scene would never recover. Interrogating this pivotal episode in the Yorkville narrative, this paper explores the role of local media in the acceleration and dissemination of fears associated with a Hepatitis outbreak that, really, never was.

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24

Butler, David. "The Days Do Not End: Film Music, Time and Bernard Herrmann." Film Studies 9, no. 1 (2006): 51–63. http://dx.doi.org/10.7227/fs.9.8.

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The tendency in most writing on the temporal properties of film music has been to note music‘s ability to establish, quickly and efficiently, a films historical setting. Although acknowledging this important function, this paper seeks to explore a wider range of temporal properties fulfilled by film music. Three aspects of musics temporality are discussed: anachronism (whereby choices of anachronistic music can provide the spectator with ways of making sense of a films subtext or its characters’ state of mind), navigation (the ability of music to help the spectator understand where and when they are in a films narrative) and expansion (musics ability to expand our experience of film time). The paper focuses on Bernard Herrmann, and his score for Taxi Driver (1976), and argues that Herrmann was particularly sensitive to the temporal possibilities of film music.

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25

Eden, Bradford Lee. "End of Days: An Encyclopedia of the Apocalypse in World Religions." Reference Reviews 32, no. 2 (February 19, 2018): 3–4. http://dx.doi.org/10.1108/rr-10-2017-0199.

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ROSENBERGER, NANCY. "Final Days: Japanese Culture and Choice at the End of Life." American Anthropologist 108, no. 4 (December 2006): 906–8. http://dx.doi.org/10.1525/aa.2006.108.4.906.

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Lawrence, John Shelton. "Glorious Appearing: The End of Days (Left Behind Series No. 12)." Journal of American Culture 28, no. 1 (March 2005): 138–41. http://dx.doi.org/10.1111/j.1542-734x.2005.160_12.x.

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Campbell, Neil. ""The Seam of Something Else Unnamed": Sebastian Barry's Days Without End." Western American Literature 53, no. 2 (2018): 231–52. http://dx.doi.org/10.1353/wal.2018.0044.

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Davies, Philip R. ""Age of Wickedness" or "End of Days"?: Qumran Scholarship in Prospect." Hebrew Studies 34, no. 1 (1993): 7–19. http://dx.doi.org/10.1353/hbr.1993.0020.

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Salamachin, M. P., T. S. Dergacheva, O. V. Leonov, D. V. Sidorov, A. O. Soloviev, and A. O. Leonova. "Manual intracorporeal end-to-end invagination ileotransverse anastomosis, own experience." Koloproktologia 20, no. 1 (March 18, 2021): 23–31. http://dx.doi.org/10.33878/2073-7556-2021-20-1-23-31.

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Aim: to evaluate the results of original manual intracorporeal end-to-end invagination ileotransverse anastomosis after laparoscopic right hemicolectomy.Patients and methods: twenty-two patients with right colon cancer were included in the study: 17 females and 5 males aged 53.1±3.4 years. They underwent laparoscopic right hemicolectomy with the standard D2 lymphadenectomy and intracorporeal ileotransverse anastomosis by the original technique. Follow-up period after surgery was 3 months.Results: no conversions to open surgery occurred. The operation time was 120.0±12.5 minutes, the median blood loss was 87.0±5.0 ml. Twenty (90.9%) patients are still under follow-up. The hospital stay was 11.4±2.6 days. There were no intraoperative complications. There were no cases of anastomotic leakage. No mortality occurred. At the time of the follow-up, all the patients are alive. Two (9.1%) patients have dropped out of control.Conclusion: the experience of the first 22 laparoscopic right hemicolectomies with intracorporeal laparoscopic end-to-end invagination ileotransverse anastomosis makes it possible to recommend this reliably safe method.

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Hultgren, Stephen. "“A Vision for the End of Days”: Deferral of Revelation in Daniel and at the End of Mark." Zeitschrift für die neutestamentliche Wissenschaft 109, no. 2 (August 10, 2018): 153–84. http://dx.doi.org/10.1515/znw-2018-0010.

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Abstract An important clue to the meaning of Mark 16,8 has not received adequate attention. The verse is an intertextual allusion to Dan 10,7. Daniel 10–12 establishes a pattern of revelation, concealment, and future revelation, in which the resurrection of the dead is apocalyptically deferred – its truth not confirmable until it happens at the end of days. A similar pattern of concealment and revelation characterizes Mark’s gospel. At the end of the gospel, the resurrection of Jesus is announced (and so revealed) in story time, but further concealed in discourse time. In the act of narrating, the message is once again revealed. With the omission of a resurrection appearance, however, the vision of the risen Lord remains concealed until the revelation of the Son of Man at the parousia.

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Glisch, Chad, Travis Snyders, Stephanie Gilbertson-White, Yuya Hagiwara, Mohammed M. Milhem, and Laurel Lyckholm. "Immune checkpoint inhibitor use near the end of life." Journal of Clinical Oncology 37, no. 15_suppl (May 20, 2019): 11533. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.11533.

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11533 Background: Studies of chemotherapy near the end of life reveal increased costs, adverse effects and minimal clinical benefit. Immune Checkpoint Inhibitor (ICI) use near the end of life has not been described. We studied factors related to ICI use near the end of life. Methods: We conducted a single-institution retrospective chart review of patients who received ICI and died between August 2014 and December 2018. End of life ICI (EOL-ICI) was defined as treatment within the last 30 days of life and comparisons were made to patients who received treatment > 30 days from end of life (non EOL-ICI). Results: 441 patients were reviewed. Mean age was 64 and 182 (41%) were female. 294 (67%) received ICI within the last 90 days of life and 117 (27%) within the last 30 days of life. At time of last ICI, 145 (33%) had brain metastases and 416 (94%) were stage 4. The most common cancers were melanoma (124, 28%), NSCLC (118, 27%) and urothelial carcinoma (34, 8%). The EOL-ICI group had a higher proportion of patients with ECOG ≥3 at time of last treatment (22% vs. 7%, p = < .001), higher rate of death in hospital (32% vs. 18%, p = 0.003) and lower hospice enrollment (52% vs. 76%, p = < .001). The EOL-ICI group received fewer ICI doses (mean 5.1 vs 6.7, p = 0.016). A higher proportion of patients in the EOL-ICI group were just beginning treatment and received ≤ 3 doses (60% vs 40%, p < .001). There was no difference in mean age or presence of brain metastases between the groups. Even when the cutoff for EOL-ICI is extended from 30 to 90 days, there remain significant differences in ECOG, hospice enrollment and starting ICI but no difference in rate of dying in the hospital. Conclusions: One out of four patients studied received ICI within the last 30 days of life. EOL-ICI treatment is associated with higher rates of death in the hospital and lower hospice enrollment. Our results suggest that performance status is important when considering treatment with ICI. Use of ICI in the last 30 days of life had minimal clinical benefit and high cost.

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Karuturi, Meghan Sri, Kimberson Tanco, Jung Hye Kwon, Tao Zhang, Wadih Rhondali, Jung Hun Kang, Gary B. Chisholm, Eduardo Bruera, and David Hui. "Targeted agent (TA) use at the end of life (EOL)." Journal of Clinical Oncology 30, no. 15_suppl (May 20, 2012): e19603-e19603. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.e19603.

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e19603 Background: Chemotherapy in the last days of life has questionable benefit and has been proposed as an indicator of poor quality of EOL care. The use of TAs at the EOL has not been examined. We determined the proportion and predictors of TA use in the last 30 days of life. Methods: All adult patients in the Houston area who died of advanced cancer between 9/1/2009 and 2/28/2010 while under the care of our institution were included. We collected baseline demographics and data on chemotherapy and TAs. Multivariate logistic regression was used to identify predictors of targeted therapy use. Results: 912 patients were included: average age 63 (range 21-98), female 49%, Caucasian 63%. Within the last 30 and 14 days of life, 117 (13%) and 56 (6%) patients received TAs, respectively, while 148 (16%) and 65 (7%) received chemotherapy. The interval between last TA use and death was 49 (21-106) days. Regimens given in the last 30 days of life included a median of 2 (1-2) chemotherapeutic/targeted agents, and the most common TAs were erlotinib (N=22), bevacizumab (N=19), rituximab (N=9), gemtuzumab (N=9) and temsirolimus (N=8). 43/117 (37%) patients who received TAs within the last 30 days of life had concurrent chemotherapy. In multivariate analysis, younger age and hematologic malignancies were associated with increased TA use (Table). Conclusions: TAs were used as often as chemotherapy at the EOL, particularly among younger patients and those with hematologic malignancies. Use of TAs in the last 30 days of life may have implications for quality of EOL care. [Table: see text]

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Wiesenthal, Alison, Anabella Lucca Bianchi, Vinnidhy Dave, Robert Sidlow, Susan Seo, and Deborah Korenstein. "Inpatient care at the end of life: A closer look." Journal of Clinical Oncology 33, no. 29_suppl (October 10, 2015): 43. http://dx.doi.org/10.1200/jco.2015.33.29_suppl.43.

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43 Background: Goals of care discussions in the inpatient setting often focus on the limitation of cardiopulmonary resuscitation and Allow Natural Death (AND) directives; decisions regarding medication administration and further diagnostic studies may be missing from the conversation. De-prescribing at the end of life (EOL) can be emotionally complex for patients and their families, though data is emerging that quality of life may be enhanced by limiting unnecessary medications. Our study assessed care in the last 3 days of life for cancer patients who die in hospital. Methods: Retrospective chart review of all inpatient deaths at a tertiary cancer center between 12/1/2012 and 11/30/2014. The frequency of lab draws, administered medications, and subspecialty consultations during the last 3 days of life were recorded. Results: Of the 1,311 inpatient deaths during the two year study period, 44% had Palliative Medicine consultation. On average, Palliative Medicine was consulted 6.5 days before death, with a median consultation time of 3 days before death. Do not resuscitate (DNR) orders were active for over 80% of patients at the time of death, with an average DNR enacted 4.6 days prior to death (range 0-60 days). Medications most often provided at the end of life were analgesics, fluids, and antibiotics (See Table 1). Consistent with Quality Oncology Practice Initiative (QOPI) Measures, <1% of patients were treated with chemotherapy in the last 3 days of life. Most patients (85%) had laboratory tests in their final 3 days of life, with a mean of 21 orders per patient. Conclusions: Non-palliative services are often provided to hospitalized patients at the end of life. Careful consideration must be given to the potential benefits and harms of medical interventions at the EOL to improve quality of life for the dying patient. Further research is needed to understand the drivers behind the care provided at EOL to inform educational tools for clinicians. [Table: see text]

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Thier, Katrin, Bernadette Calabek, Alexander Tinchon, Wolfgang Grisold, and Stefan Oberndorfer. "The Last 10 Days of Patients With Glioblastoma." American Journal of Hospice and Palliative Medicine® 33, no. 10 (July 11, 2016): 985–88. http://dx.doi.org/10.1177/1049909115609295.

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Background: High-grade gliomas are the most frequent primary brain tumors. Despite improvement in diagnostics and treatment, survival is still poor and quality-of-life issues are of major importance. Little is known regarding the clinical signs and symptoms of dying patients with glioblastoma. Objective: The aim of this study was to investigate signs and symptoms as well as therapeutic strategies in patients with glioblastoma in the end-of-life phase in order to improve end-of-life care. Methods: In this prospective single-center study, clinical data were obtained using a standardized protocol. We descriptively analyzed signs, symptoms, and therapeutic strategies on a daily basis. Results: A total of 57 patients, who died due to glioblastoma in a hospital setting, were included. The most frequent signs and symptoms in the last 10 days before death were decrease in level of consciousness (95%), fever (88%), dysphagia (65%), seizures (65%), and headache (33%). Concerning medication, 95% received opioids. There was a high need for nonsteroidal anti-inflammatory drugs (77%) and anticonvulsants (75%). Steroids were given to 56%. Conclusion: Due to a decrease in level of consciousness and cognitive impairment, assessment of clinical signs and symptoms such as headache at the end of life is difficult. Based on the signs and symptoms in the last days before death in patients with glioblastoma, supportive drug treatment remains challenging. Our study emphasizes the importance of standardized guidelines for end-of-life care in patients with glioblastoma.

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Avbelj, Matej. "Brexit: An End to the End of History." German Law Journal 17, S1 (July 1, 2016): 1–6. http://dx.doi.org/10.1017/s207183220002160x.

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Britain has voted to withdraw from the European Union. This is a victory. For European populists. For Putin's Russia. As well as for the new world system of governance, what Victor Orban has called “illiberal democracy.” The era of the modern West, in the form that emerged out of the ashes of the WWII, is coming to an end. The West alone is to be blamed for that. As it has been hit by one crisis after the other, the West has continued to merely scratch the surface in looking for ad hoc, immediate, and almost exclusively economic solutions. The emphasis is always on the symptoms but never on the disease. In so doing, the West has turned a blind eye on a process of deep, internal transformation. The post-Brexit debate that will ensue in the following days and months will most likely stay faithful to this legacy. The discussion will remain superficial, preoccupied with economic and political questions, limited to the short-term quests of reorganizing the EU in pursuit of its long-term viability. But I want to insist that the challenge is much bigger than the future of the EU. It is about the preservation of the West, understood here as a synonym for liberal democracy and the commitment to the rule of law. We are confronted with the difficult—even terrifying question: How are we to build a new modernity on the debris of the modern post-war West in order to avoid repeating the bitter historical experiences of the pre-war Europe.

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Juříček, Lukáš, Miloš Zich, Michal Hasa, Petra Komárková, and Lukáš Bobek. "Precast Dapped End - Nonlinear Analysis." Solid State Phenomena 322 (August 9, 2021): 106–10. http://dx.doi.org/10.4028/www.scientific.net/ssp.322.106.

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The article follows the results from the experiments published at the conferences Concrete days 2014 [1] and 2016 [2], in the paper [3], and also in the magazine Beton TKS [4]. The goal of the experiment was the verification of dapped ends with the different configuration of the hanger stirrups. Subsequently, the nonlinear analyses were performed in the scientific program ATENA. In this article, a new comparison with calculations using the CSFM (Compatible Stress Field Method), implemented in software IDEA StatiCa Detail, is performed

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Omura, Tomoko, Yasuji Miyakita, Makoto Ohno, Masamichi Takahashi, Kenji Fujimoto, Takaki Omura, Hitomi Sato, and Yoshitaka Narita. "QOLP-40. END-OF-LIFE CARE FOR GLIOBLASTOMA PATIENTS IN JAPAN." Neuro-Oncology 21, Supplement_6 (November 2019): vi206—vi207. http://dx.doi.org/10.1093/neuonc/noz175.860.

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Abstract BACKGROUND Despite aggressive treatment with surgery and chemo-radiation therapy, it is difficult to cure patients with glioblastoma (GBM). The end-of-life (EOL) phase of patients with GBM, and related problems, have not yet been adequately studied. Unlike in other countries, most cancer patients died in the hospital (84%) in 2017, but the Japanese government has recommended palliative home care and the number of deaths at home has recently been increasing. This study explores the current situation of EOL care for GBM patients in Japan. METHODS We retrospectively examined the clinical course and EOL phase of 166 consecutive patients who were treated in our hospital between 2010 and 2017. RESULT: In total, 107 patients died; 27 (25.7%) at home, 24 (22.8%) in hospice care, 8 (7.6%) in nursing homes, 46 (43.9%) in hospitals (long-term care hospitals [LTCH; 19.8%], our hospital [13.3%], and other neurosurgical hospitals [10.4%]). According to our previous research, in 2001–2005, 6% of GBM patients died at home, 3% in hospice case, and 91% in the hospital. The KPSof patients who started palliative home care or transferred to another hospital was 50–60. The median survival time and length of EOL phase for patients who died at home were 498 and 76.5 days; 395 and 103 days in hospice care; 533 days and 149 days in LTCH; 374 days and 52 days in our hospital; 338 and 75.5 days in other neurosurgical hospital; and 557 days and 37 days in nursing homes, respectively. CONCLUSION The number of GBM patients who died at home in Japan is increasing, and we must consider the problems of the EOL phase and improve the quality of EOL care.

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S.K.Manigandan, Mr, Mrs R.Latha, Mr S.MohamedAsik, J. Velmurugan, and D. Ramya. "Providing a Live Chat on Online Shopping with End-to-End Encryption." International Journal of Engineering & Technology 7, no. 3.34 (September 1, 2018): 133. http://dx.doi.org/10.14419/ijet.v7i3.34.18789.

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In our these days life on-line purchase associated e-commerce website has changing into an mandatory things in our daily life vogue since, it conjointly have some major issue like purchasing a product with unhappy mode and lack of data in product usage. therefore as to overcome these drawback we have a tendency to have new entranceway referred to as live chat in on-line looking. We have a tendency to will offer this live chat in most safest method exploitation the end to finish cryptography methodology , most of the looking can have a live chat however they Weren’t provided a cut price options and most e-commerce website don’t have Chat choices. We have a tendency to will even enable the client and producer to Share their thoughts.

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MacBride, Fraser. "Analytic Philosophy and its Synoptic Commission: Towards the Epistemic End of Days." Royal Institute of Philosophy Supplement 74 (June 30, 2014): 221–36. http://dx.doi.org/10.1017/s1358246114000095.

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AbstractThere is no such thing as ‘analytic philosophy’, conceived as a special discipline with its own distinctive subject matter or peculiar method. But there is an analytic task for philosophy that distinguishes it from other reflective pursuits, a global or synoptic commission: to establish whether the final outputs of other disciplines and common sense can be fused into a single periscopic vision of the Universe. And there is the hard-won insight that thought and language aren't transparent but stand in need of analysis – a recent variation upon the abiding philosophical theme that we need to get behind appearances to tell the ultimate truth about reality – an insight that threatens to be lost once philosophers appeal to intuitions.

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Soage, Ana Belén. "The End of Days: Essays on the Apocalypse from Antiquity to Modernity." Totalitarian Movements and Political Religions 10, no. 3-4 (September 2009): 375–77. http://dx.doi.org/10.1080/14690760903396385.

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Roberts, Allen F. "Icons from the end of days: Visual hagiography among Layennes of Senegal." World Art 3, no. 2 (September 2013): 235–58. http://dx.doi.org/10.1080/21500894.2012.746896.

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McDonald, Michael. "Dignity at the End of Our Days: Personal, Familial, and Cultural Location." Journal of Palliative Care 20, no. 3 (September 2004): 163–70. http://dx.doi.org/10.1177/082585970402000308.

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Nakano, Lynne Y. "Final Days: Japanese Culture and Choice at the End of Life (review)." Journal of Japanese Studies 33, no. 1 (2007): 239–43. http://dx.doi.org/10.1353/jjs.2007.0029.

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Davis, Jane. "In at the deep end: two days with the Link Up game." Electronics Education 1994, no. 1 (1994): 36–39. http://dx.doi.org/10.1049/ee.1994.0026.

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Smith, Carlyle, and Gina Kelly. "Paradoxical sleep deprivation applied two days after end of training retards learning." Physiology & Behavior 43, no. 2 (January 1988): 213–16. http://dx.doi.org/10.1016/0031-9384(88)90240-5.

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Althoff, Klaus-Dieter, and Hermann Engesser. "End of days…? Oder wie die KI-Zeitschrift in 10 Jahren aussieht." KI - Künstliche Intelligenz 25, no. 4 (October 15, 2011): 335–36. http://dx.doi.org/10.1007/s13218-011-0131-x.

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Editorial. "“VGIK DAYS”: FOREIGN ROUTES." Journal of Flm Arts and Film Studies 10, no. 4 (December 15, 2018): 6. http://dx.doi.org/10.17816/vgik1046-6.

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The international ties of VGIK with universities and national schools of different countries are developing rapidly. Confirmation is the 38th VGIK International Student Film Festival, which was successfully completed in Moscow, or the Student Oscar, as the Russian press calls it. In anticipation of the celebration of the 100th anniversary of the celebrated Russian university and the 120th anniversary of Sergei Eisenstein, the festival was attended by future cinematographers from 38 film schools from 36 countries presented 43 films for the competition program. Another proof is the holding of VGIK Days, which took place at the end of 2018 in the Republic of Belarus and the Republic of Uzbekistan, Italy, and Romania. And everywhere delegation VGIK waited for a warm and friendly welcome.

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Sánchez-Cuervo, Marina, Lorena García-Basas, Esther Gómez de Salazar-López de Silanes, Cristina Pueyo-López, and Teresa Bermejo-Vicedo. "Chemotherapy Near the End of Life in Onco–Hematological Adult Patients." American Journal of Hospice and Palliative Medicine® 37, no. 8 (January 23, 2020): 641–47. http://dx.doi.org/10.1177/1049909119901133.

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Objective: The use of chemotherapy near the end of life is not advisable. There are scarce data in Europe but shows signs of aggressiveness. We designed this study to analyze the proportion of onco–hematological patients receiving chemotherapy within their last 2 weeks of life as well as starting a new chemotherapy regimen in the 30 days prior to death. Methods: A retrospective observational study was conducted in a tertiary hospital. Adults who died of an onco-hematological neoplasia while hospitalized between April 2017 and March 2018 were included. We assessed the use of chemotherapy over the course of the last 14 days of life, defined as the administration of at least one dose of chemotherapy. We also examined the proportion of patients starting a new chemotherapy regimen in the last 30 days of life. Results: A total of 298 inpatients died in the Hematology and Oncology units. During the last 14 days, 28.2% (n = 11) of hematological and 26.3% (n = 68) of oncological patients received chemotherapy; the overall rate was 26.5% (n = 79). Furthermore, the proportion of patients starting a new chemotherapy regimen in the last 30 days of life was high (20.5% and 20.8%, respectively). Female gender (odds ratio [OR] = 1.99, 95% confidence interval [CI] = 1.18-3.35) and age <45 (OR = 2.68, 95% CI = 1.05-6.88) were associated with higher rates of chemotherapy. Conclusion: The proportion of patients receiving chemotherapy in the last 14 days of life was high, as well as the proportion of patients starting a new regimen in their last 30 days. This was indicative of excessive aggressiveness at the end-of-life care.

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Stipp-Brambilla, Elisangela Jeronymo, Fausto Viterbo, Daniel Labbé, José Antonio Garbino, and Maíra Miranda Bernardelli. "Double muscle innervation using end-to-side neurorrhaphy in rats." Sao Paulo Medical Journal 130, no. 6 (2012): 373–79. http://dx.doi.org/10.1590/s1516-31802012000600004.

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CONTEXT AND OBJECTIVE: One of the techniques used for treating facial paralysis is double muscle innervation using end-to-end neurorrhaphy with sectioning of healthy nerves. The aim of this study was to evaluate whether double muscle innervation by means of end-to-side neurorrhaphy could occur, with maintenance of muscle innervation. DESIGN AND SETTING: Experimental study developed at the Experimental Research Center, Faculdade de Medicina de Botucatu, Unesp. METHODS: One hundred rats were allocated to five groups as follows: G1, control group; G2, the peroneal nerve was sectioned; G3, the tibial nerve was transected and the proximal stump was end-to-side sutured to the intact peroneal nerve; G4, 120 days after the G3 surgery, the peroneal nerve was sectioned proximally to the neurorrhaphy; G5, 120 days after the G3 surgery, the peroneal and tibial nerves were sectioned proximally to the neurorrhaphy. RESULTS: One hundred and fifty days after the surgery, G3 did not show any change in tibial muscle weight or muscle fiber diameter, but the axonal fiber diameter in the peroneal nerve distal to the neurorrhaphy had decreased. Although G4 showed atrophy of the cranial tibial muscle 30 days after sectioning the peroneal nerve, the electrophysiological test results and axonal diameter measurement confirmed that muscle reinnervation had occurred. CONCLUSION: These findings suggest that double muscle innervation did not occur through end-to-side neurorrhaphy; the tibial nerve was not able to maintain muscle innervation after the peroneal nerve had been sectioned, although muscle reinnervation was found to have occurred, 30 days after the peroneal nerve had been sectioned.

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Journal articles on the topic 'End of Days'

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