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Journal articles on the topic 'End Systolic Volume (ESV)'

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Published: 5 June 2025

Last updated: 2 August 2025

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1

Sandor, George G. S., Ruby Popv, and Judith G. Hall. "135 CORRELATION OF PEAK SYSTOLIC PRESSURE/END SYSTOLIC VOLUME(PSP/ESV) AND END SYSTOUC PRESSURE/END SYSTOLIC VOLUME (ESP/ESV) RATIOS." Pediatric Research 19, no. 4 (1985): 133A. http://dx.doi.org/10.1203/00006450-198504000-00165.

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Renlund, D. G., G. Gerstenblith, J. L. Fleg, L. C. Becker, and E. G. Lakatta. "Interaction between left ventricular end-diastolic and end-systolic volumes in normal humans." American Journal of Physiology-Heart and Circulatory Physiology 258, no. 2 (1990): H473—H481. http://dx.doi.org/10.1152/ajpheart.1990.258.2.h473.

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The extent to which the end-systolic volume (ESV) “follows” the end-diastolic volume (EDV) when the latter changes in response to various perturbations is a major determinant of the cardiac ejection fraction (EF) and has not been studied in humans. We measured EDV, ESV, and EF, determined by gated blood pool scans, during a change in posture from the supine to the upright seated position and during graded upright bicycle exercise. The experimental group consisted of 119 healthy individuals (79 males and 40 females) ranging in age from 21 to 81 yr and in physical-conditioning status (75–225 W m

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Lentini, A. C., R. S. McKelvie, N. McCartney, C. W. Tomlinson, and J. D. MacDougall. "Left ventricular response in healthy young men during heavy-intensity weight-lifting exercise." Journal of Applied Physiology 75, no. 6 (1993): 2703–10. http://dx.doi.org/10.1152/jappl.1993.75.6.2703.

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We examined cardiac volumes (using echocardiography), intra-arterial blood pressure (BP), and intrathoracic pressure (ITP) in healthy males performing leg press exercise to failure at 95% of their maximum dynamic strength. Compared with preexercise, during the lifting phase of exercise, end-diastolic volume (EDV; 147 +/- 8 to 103 +/- 7 ml) and end-systolic volume (ESV; 54 +/- 5 to 27 +/- 4 ml) decreased (P < 0.05); heart rate (82 +/- 6 to 143 +/- 5 beats/min), systolic BP (160 +/- 6 to 270 +/- 21 Torr), diastolic BP (91 +/- 2 to 183 +/- 18 Torr), ITP (0.8 +/- 0.8 to 57.8 +/- 24 Torr), and p

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Faes, Theo J. C., and Peter L. M. Kerkhof. "The Volume Regulation Graph versus the Ejection Fraction as Metrics of Left Ventricular Performance in Heart Failure with and without a Preserved Ejection Fraction: A Mathematical Model Study." Clinical Medicine Insights: Cardiology 9s1 (January 2015): CMC.S18748. http://dx.doi.org/10.4137/cmc.s18748.

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In left ventricular heart failure, often a distinction is made between patients with a reduced and a preserved ejection fraction (EF). As EF is a composite metric of both the end-diastolic volume (EDV) and the end-systolic ventricular volume (ESV), the lucidity of the EF is sometimes questioned. As an alternative, the ESV–EDV graph is advocated. This study identifies the dependence of the EF and the EDV–ESV graph on the major determinants of ventricular performance. Numerical simulations were made using a model of the systemic circulation, consisting of an atrium–ventricle valves combination;

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Kirschfink, Annemarie, Michael Frick, Ghazi Al Ateah, et al. "Evaluation of the Truncated Cone–Rhomboid Pyramid Formula for Simplified Right Ventricular Quantification: A Cardiac Magnetic Resonance Study." Journal of Clinical Medicine 13, no. 10 (2024): 2850. http://dx.doi.org/10.3390/jcm13102850.

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Background/Objective: Cardiac magnetic resonance (CMR) is the reference method for right ventricular (RV) volume and function analysis, but time-consuming manual segmentation and corrections of imperfect automatic segmentations are needed. This study sought to evaluate the applicability of an echocardiographically established truncated cone–rhomboid pyramid formula (CPF) for simplified RV quantification using CMR. Methods: A total of 70 consecutive patients assigned to RV analysis using CMR were included. As standard method, the manual contouring of RV-short axis planes was performed for the m

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Atalay, Michael K., Kevin J. Chang, David J. Grand, Shawn Haji-Momenian, Jason T. Machan, and Florence H. Sheehan. "The Transaxial Orientation Is Superior to Both the Short Axis and Horizontal Long Axis Orientations for Determining Right Ventricular Volume and Ejection Fraction Using Simpson's Method with Cardiac Magnetic Resonance." ISRN Cardiology 2013 (April 14, 2013): 1–9. http://dx.doi.org/10.1155/2013/268697.

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We sought to determine which of the three orientations is the most reliable and accurate for quantifying right ventricular (RV) volume and ejection fraction (EF) by cardiac magnetic resonance using Simpson’s method. We studied 20 patients using short axis (SA), transaxial (TA), and horizontal long axis (HLA) orientations. Three readers independently traced RV endocardial contours at end-diastole and end-systole for each orientation. End-diastolic volumes (EDVs), end-systolic volumes (ESVs), and EF were calculated and compared with the 3D piecewise smooth subdivision surface (PSSS) method. The

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Denault, Andre Y., John Gorcsan, and Michael R. Pinsky. "Dynamic effects of positive-pressure ventilation on canine left ventricular pressure-volume relations." Journal of Applied Physiology 91, no. 1 (2001): 298–308. http://dx.doi.org/10.1152/jappl.2001.91.1.298.

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Positive-pressure ventilation (PPV) may affect left ventricular (LV) performance by altering both LV diastolic compliance and pericardial pressure (Ppc). We measured the effect of PPV on LV intraluminal pressure, Ppc, LV volume, and LV cross-sectional area in 17 acute anesthetized dogs. To account for changes in lung volume independent of changes in Ppc and differences in contractility, measures were made during both open- and closed-chest conditions, during closed chest with and without chest wall binding, and after propranolol-induced acute ventricular failure (AVF). Apneic end-systolic pres

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8

Lisytenko, N. S., N. A. Morova, and V. N. Tsekhanovich. "Predicting coronary graft occlusion in males with type 2 diabetes: an annual prospective study." Kuban Scientific Medical Bulletin 27, no. 4 (2020): 189–200. http://dx.doi.org/10.25207/1608-6228-2020-27-4-189-200.

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Aim. Identiﬁcation of factors affecting coronary bypass graft patency in patients with type 2 diabetes (T2D) during one year after coronary bypass grafting.Materials and methods. Coronary artery bypass grafting for stable effort angina was ordered in 23 men with T2D. The patients had transthoracic echocardiogram before surgery. All patients were veriﬁed for lupus anticoagulant (LA) in blood on the 14th day after surgery. A year later, the patients underwent coronary shuntography to assess bypass patency.Results. LA was detected in 15 of 23 patients (65%). One year after surgery, occlusions of

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Mohammed, M. K., and S. I. Essa. "The effect of left ventricle ischemia severity on cardiac performance appeared on ejection fraction using radioactive TC ^99m MIBI in comparison with echocardiography." Journal of Physics: Conference Series 2114, no. 1 (2021): 012006. http://dx.doi.org/10.1088/1742-6596/2114/1/012006.

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Abstract Ischemic heart disease is a major causes of heart failure. Heart failure patients have predominantly left ventricular dysfunction (systolic or diastolic dysfunction, or both). Acute heart failure is most commonly caused by reduced myocardial contractility, and increased LV stiffness. We performed echocardiography and gated SPECT with Tc99m MIBI within 263 patients and 166 normal individuals. Left ventricular end systolic volume (LVESV), left ventricular end diastolic volume (LVEDV), and left ventricular ejection fraction (LVEF) were measured. For all degrees of ischemia, there was a s

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Dong, Sheng-Jing, Paul S. Hees, Wen-Mei Huang, Sam A. Buffer, James L. Weiss, and Edward P. Shapiro. "Independent effects of preload, afterload, and contractility on left ventricular torsion." American Journal of Physiology-Heart and Circulatory Physiology 277, no. 3 (1999): H1053—H1060. http://dx.doi.org/10.1152/ajpheart.1999.277.3.h1053.

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Shortening of oblique left ventricular (LV) fibers results in torsion. A unique relationship between volume and torsion is therefore expected, and the effects of load and contractility on torsion should be predictable. However, volume-independent behavior of torsion has been observed, and the effects of load on this deformation remain controversial. We used magnetic resonance imaging (MRI) with tagging to study the relationships between load and contractility, and torsion. In ten isolated, blood-perfused canine hearts, ejection was controlled by a servopump: end-diastolic volume (EDV) was cont

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Al Ateah, Ghazi, Annemarie Kirschfink, Michael Frick, et al. "Echocardiographic determination of right ventricular volumes and ejection fraction: Validation of a truncated cone and rhomboid pyramid formula." PLOS ONE 18, no. 8 (2023): e0290418. http://dx.doi.org/10.1371/journal.pone.0290418.

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Background Echocardiographic assessment of right ventricular (RV) measurements may be challenging. The aim of this study was to develop a formula for calculation of RV volumes and function based on measurements of linear dimensions by 2-dimensional (2D) transthoracic echocardiography (TTE) in comparison to cardiovascular magnetic resonance (CMR). Methods 129 consecutive patients with standard TTE and RV analysis by CMR were included. A formula based on the geometric assumptions of a truncated cone minus a truncated rhomboid pyramid was developed for calculations of RV end-diastolic volume (EDV

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Magalhães Neto, Anibal Monteiro de, Nathália Maria Resende, Carlos Kusano Bucalen Ferrari, et al. "Echocardiographic analysis of the left ventricular function in elderly runners." ConScientiae Saúde 13, no. 4 (2015): 499–505. http://dx.doi.org/10.5585/conssaude.v13n4.4916.

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Introduction: During the aging process, cardiovascular function suffers intense changes. Objective: To perform an echocardiographic evaluation of left ventricular function in elderly male athletes and non-athletes. Methods: Eleven elderly males were separated into two groups: group A, with six non-athletes (61.66 ± 3.20y) and group B, with eight athletes (62.75 ± 3.24y). Two-dimensional and M mode color Doppler echocardiography were used to assess heart rate (HR), stroke volume (SV), diastolic dimension (DD), systolic dimension (SD), end diastolic volume (EDV), end systolic volume (ESV), mass

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Kadam, Satar M. "The Left ventricular ejection fraction and left ventricular volumes assessed from 99mTC single photon emission tomography technique during stress and rest in relation to age in normal volunteer students." Sumer 1 8, CSS 1 (2023): 1–7. http://dx.doi.org/10.21931/rb/css/s2023.08.01.22.

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The heart is subject to structural and functional changes with advancing age. Left ventricular compliance appears to decline with age, which could explain why the elderly have such a high rate of heart failure. Changes in heart function with age are associated with an increased risk of cardiovascular death and morbidity. Various techniques have been used to measure the impact of age on heart structure and function. Subject and methods: The study included 221 healthy adult male and female volunteers (160 females and 61 males, 20–80 years of age). All healthy subjects volunteered to participate

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Tomczak, Corey R., Richard B. Thompson, Ian Paterson, et al. "Effect of acute high-intensity interval exercise on postexercise biventricular function in mild heart failure." Journal of Applied Physiology 110, no. 2 (2011): 398–406. http://dx.doi.org/10.1152/japplphysiol.01114.2010.

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We studied the acute effect of high-intensity interval exercise on biventricular function using cardiac magnetic resonance imaging in nine patients [age: 49 ± 16 yr; left ventricular (LV) ejection fraction (EF): 35.8 ± 7.2%] with nonischemic mild heart failure (HF). We hypothesized that a significant impairment in the immediate postexercise end-systolic volume (ESV) and end-diastolic volume (EDV) would contribute to a reduction in EF. We found that immediately following acute high-intensity interval exercise, LV ESV decreased by 6% and LV systolic annular velocity increased by 21% (both P <

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Kerkhof, Peter L. M. "Characterizing Heart Failure in the Ventricular Volume Domain." Clinical Medicine Insights: Cardiology 9s1 (January 2015): CMC.S18744. http://dx.doi.org/10.4137/cmc.s18744.

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Heart failure (HF) may be accompanied by considerable alterations of left ventricular (LV) volume, depending on the particular phenotype. Two major types of HF have been identified, although heterogeneity within each category may be considerable. All variants of HF show substantially elevated LV filling pressures, which tend to induce changes in LV size and shape. Yet, one type of HF is characterized by near-normal values for LV end-diastolic volume (EDV) and even a smaller end-systolic volume (ESV) than in matched groups of persons without cardiac disease. Furthermore, accumulating evidence i

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Michler, Kerstin, Christopher Hessman, Marcus Prümmer, Stephan Achenbach, Michael Uder, and Rolf Janka. "Cardiac MRI: An Alternative Method to Determine the Left Ventricular Function." Diagnostics 13, no. 8 (2023): 1437. http://dx.doi.org/10.3390/diagnostics13081437.

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(1) Background: With the conventional contour surface method (KfM) for the evaluation of cardiac function parameters, the papillary muscle is considered to be part of the left ventricular volume. This systematic error can be avoided with a relatively easy-to-implement pixel-based evaluation method (PbM). The objective of this thesis is to compare the KfM and the PbM with regard to their difference due to papillary muscle volume exclusion. (2) Material and Methods: In the retrospective study, 191 cardiac-MR image data sets (126 male, 65 female; median age 51 years; age distribution 20–75 years)

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Kamińska, Halszka, Łukasz A. Małek, Marzena Barczuk-Falęcka, and Bożena Werner. "Usefulness of three-dimensional echocardiography for assessment of left and right ventricular volumes in children, verified by cardiac magnetic resonance. Can we overcome the discrepancy?" Archives of Medical Science 17, no. 1 (2021): 71–83. http://dx.doi.org/10.5114/aoms.2019.84215.

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IntroductionThe role of three-dimensional echocardiography (3D-ECHO) chamber quantification in children is still underestimated.Material and methodsIn 43 children 3D-ECHO measurements of end-diastolic (EDV) and end-systolic ventricular volumes (ESV) were compared to cardiac magnetic resonance (CMR) using Bland-Altman analysis and linear regression. The values of left and right ventricular volumes calculated in 3D-ECHO were compared with each other and verified by CMR.ResultsThe values of LV-EDV and LV-ESV measured in 3D-ECHO showed highly significant correlations with CMR (for LV-EDV r = 0.892

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Gufler, Hubert, Sabine Wagner, Sabine Niefeldt, et al. "Levels of agreement between cardiac magnetic resonance and conductance catheter measurements of right ventricular volumes after pulmonary artery banding." Acta Radiologica 61, no. 7 (2019): 894–902. http://dx.doi.org/10.1177/0284185119886318.

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Background Pressure-volume analysis is the gold standard for quantifying pump function of the right ventricle (RV); however, volume measurements based on a conductive catheter may be imprecise. The reference method for volume assessment is cardiac magnetic resonance (CMR). Purpose To determine the levels of agreement between RV volume measurements obtained by cine CMR, phase-contrast CMR (PC CMR), and a conductance catheter in an animal model. Material and Methods CMR was performed in 20 sheep three months after pulmonary artery banding. Ejection fraction (EF), end-diastolic (EDV), end-systoli

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Neelam, Tandia* Navdeep Singh Dharmendra Kumar Priya Singh Arun Mourya and Shilpa Gajbhiye. "COMPARISON OF ECHOCARDIOGRAPHIC INDICES OF NORMAL BUFFALOES AND THOSE HAVING DIAPHRAGMATIC HERNIA." ANNALS OF FOREST RESEARCH 67, no. 1 (2024): 263–71. https://doi.org/10.5281/zenodo.10950022.

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<strong>ABSTRACT</strong>The objective of this study was to describe the clinical presentation and evaluate echocardiographic findings in Murrah buffaloes suffering from diaphragmatic hernia. Normal buffaloes (n=15) and buffaloes  with  diaphragmatic  hernia  (n=15)  diagnosed  clinically,  radiographically, ultrasonographically  for  diaphragmatic  hernia  were  evaluated  in  this  study.  Fifteen  healthy buffaloes were included in this study as controls. The mean±SE value of left

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Nielsen, Jan Møller, Steen B. Kristiansen, Steffen Ringgaard, et al. "Left ventricular volume measurement in mice by conductance catheter: evaluation and optimization of calibration." American Journal of Physiology-Heart and Circulatory Physiology 293, no. 1 (2007): H534—H540. http://dx.doi.org/10.1152/ajpheart.01268.2006.

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The conductance catheter (CC) allows thorough evaluation of cardiac function because it simultaneously provides measurements of pressure and volume. Calibration of the volume signal remains challenging. With different calibration techniques, in vivo left ventricular volumes (VCC) were measured in mice ( n = 52) with a Millar CC (SPR-839) and compared with MRI-derived volumes (VMRI). Significant correlations between VCC and VMRI [end-diastolic volume (EDV): R2 = 0.85, P < 0.01; end-systolic volume (ESV): R2 = 0.88, P < 0.01] were found when injection of hypertonic saline in the pulmonary

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Hetyey, Cs, L. Balogh, and G. Andócs. "Comparison of echocardiography and gated equilibrium radionuclide ventriculography in the measurements of left ventricular systolic function parameters in healthy dogs." Acta Veterinaria Hungarica 50, no. 1 (2002): 21–29. http://dx.doi.org/10.1556/avet.50.2002.1.4.

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Left ventricular systolic function was assessed in 12 healthy dogs with equilibrium radionuclide ventriculography. The results of the analysis were compared to traditional echocardiographic measurements. Left ventricular internal dimensions and volume were measured at the time of end-systole and end-diastole. Ejection fraction - one of the most informative parameters of cardiac function - was calculated in each animal. Values (e.g. EDD, ESD, EDV, ESV) measured by the scintigraphic method were significantly (Student's t-test, P < 0.05) higher than the data obtained by echocardiography. Eject

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Elbeery, Jospeh R., John C. Lucke, Michael P. Feneley, et al. "Mechanical determinants of myocardial oxygen consumption in conscious dogs." American Journal of Physiology-Heart and Circulatory Physiology 270, no. 6 (1996): 1. http://dx.doi.org/10.1152/ajpheart.1996.270.6.1-a.

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Pages H609–H620: Jospeh R. Elbeery, John C. Lucke, Michael P. Feneley, George W. Maier, Clarence H. Owen, R. Eric Lilly, Michael A. Savitt, Mark St. J. Hickey, Stanley A. Gall, Jr., James W. Davis, Peter VanTrigt, J. Scott Rankin, and Donald D. Glower. “Mechanical determinants of myocardial oxygen consumption in conscious dogs.” Page H618: Equations 12, 14, and 15 should read as follows. There should only be one SW term in Eq. 12 MVo2 = Hun + Hp + Hc + SW (12) Equations 14 and 15 should contain end-diastolic volume (EDV) instead of end-systolic volume (ESV) MVo2 = Hun + k · EDV · MEP + SW (14)

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Tsutsumi, Yoshinori, Shiro Adachi, Yoshihisa Nakano, et al. "End-Systolic Eccentricity Index Obtained by Enhanced Computed Tomography Is a Predictor of Pulmonary Vascular Resistance in Patients with Chronic Thromboembolic Pulmonary Hypertension." Life 12, no. 4 (2022): 593. http://dx.doi.org/10.3390/life12040593.

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The usefulness of the parameters of biventricular function simultaneously measured using enhanced multi-detector computed tomography (MDCT) pulmonary angiography in patients with chronic thromboembolic pulmonary hypertension (CTEPH) has not been clarified. This study aimed to verify the correlation between left and right ventricular (RV) parameters and pulmonary vascular resistance (PVR). Patients who underwent enhanced MDCT before diagnostic right heart catheterization at Nagoya University Hospital between October 2014 and April 2021 were enrolled. The correlation of biventricular function an

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Koteliukh, Mariia. "Features of Changes in the Structural and Functional State of the Myocardium in Patients with Acute Myocardial Infarction Depending on Body Mass Index Considering FABP4 and CTRP3 Levels." Galician Medical Journal 28, no. 3 (2021): E202137. http://dx.doi.org/10.21802/gmj.2021.3.7.

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Introduction. Adipokines such as fatty acid-binding protein 4 (FABP4) and C1q tumor necrosis factor-related protein 3 (CTRP3) can affect the structural and functional state of the myocardium in patients with acute myocardial infarction and obesity. The objective of the research was to determine the relationship between FABP4, CTRP3 and echocardiographic parameters of the left ventricular myocardium in patients with acute myocardial infarction depending on body mass index. Materials and Methods. The observational cross-sectional study examined 189 patients with acute myocardial infa

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Pingitore, Alessandro, Angelo Gemignani, Danilo Menicucci, et al. "Cardiovascular response to acute hypoxemia induced by prolonged breath holding in air." American Journal of Physiology-Heart and Circulatory Physiology 294, no. 1 (2008): H449—H455. http://dx.doi.org/10.1152/ajpheart.00607.2007.

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Prolonged breath hold (BH) represents a valid model for studying the cardiac adaptation to acute hypoxemia in humans. Cardiac magnetic resonance (CMR) allows a three-dimensional, high-resolution, noninvasive, and nonionizing anatomical and functional evaluation of the heart. The aim of the study was to assess the adaptation of the cardiovascular system to prolonged BH in air. Ten male volunteer diving athletes (age 30 ± 6 yr) were studied during maximal BH duration with CMR. Four epochs were studied: I, rest; II and III, intermediate BH; and IV, peak BH. Oxygen saturation (So2), heart rate (HR

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Popov, K. A., I. Z. Bondarenko, E. V. Biryukova, et al. "Possibilities of predicting preclinical forms of cardiovascular diseases in young patients with type 1 diabetes mellitus using cardiac magnetic resonance imaging." Siberian Journal of Clinical and Experimental Medicine 36, no. 3 (2021): 51–58. http://dx.doi.org/10.29001/2073-8552-2021-36-3-51-58.

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Aim. To identify the indicators of cardiac magnetic resonance (CMR), which have diagnostic value in the individual assessment of the cardiovascular prognosis in young patients with type 1 diabetes mellitus (T1DM).Material and Methods. The study included a total of 60 patients (29 men and 31 women) aged 18 to 36 years with a history of T1DM from 5 to 16 years, who underwent contrast-enhanced CMR. Circular strain, strain relaxation index (SRI), peak early diastolic strain rate (SRe), epicardial fat thickness (EFT), ejection fraction (EF), stroke volume (SV), end-diastolic volume (EDV), end-systo

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Kerkhof, Peter L. M., Tatiana Kuznetsova, Rania Ali, and Neal Handly. "Left ventricular volume analysis as a basic tool to describe cardiac function." Advances in Physiology Education 42, no. 1 (2018): 130–39. http://dx.doi.org/10.1152/advan.00140.2017.

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The heart is often regarded as a compression pump. Therefore, determination of pressure and volume is essential for cardiac function analysis. Traditionally, ventricular performance was described in terms of the Starling curve, i.e., output related to input. This view is based on two variables (namely, stroke volume and end-diastolic volume), often studied in the isolated (i.e., denervated) heart, and has dominated the interpretation of cardiac mechanics over the last century. The ratio of the prevailing coordinates within that paradigm is termed ejection fraction (EF), which is the popular me

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Melandri, Monica, Ilaria Spalla, Luca Fanciullo, and Salvatore Alonge. "Pregnancy Effect on Echocardiographic Parameters in Great Dane Bitches." Animals 10, no. 11 (2020): 1992. http://dx.doi.org/10.3390/ani10111992.

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Pregnancy is associated with adaptation of the left ventricular (LV) function. Due to differences between breeds in baseline echocardiographic values and specific predispositions for myocardial diseases, breed-specific echocardiographic parameters may be helpful to evaluate whether the systolic function varies during pregnancy. This study enrolled nine healthy Great Dane bitches with uncomplicated pregnancy. Echocardiographic M-mode and B-mode data were collected before ovulation and within 7 days of the predicted parturition term. Evaluated parameters were: LV dimension in diastole (LVd) and

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Zuo, Zhi, Anne Subgang, Alireza Abaei, et al. "Assessment of Longitudinal Reproducibility of Mice LV Function Parameters at 11.7 T Derived from Self-Gated CINE MRI." BioMed Research International 2017 (2017): 1–10. http://dx.doi.org/10.1155/2017/8392952.

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The objective of this work was the assessment of the reproducibility of self-gated cardiac MRI in mice at ultra-high-field strength. A group of adult mice (n=5) was followed over 360 days with a standardized MR protocol including reproducible animal position and standardized planning of the scan planes. From the resulting CINE MRI data, global left ventricular (LV) function parameters including end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), ejection fraction (EF), and left ventricular mass (LVM) were quantified. The reproducibility of the self-gated technique as wel

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Maksimov, N. I., I. S. Grishin, and N. S. Grishina. "Comparative assessment of echocardiographic parameters, including the left ventricular global function index in patients with myocardial infarction with obstructive (MICAD) and non-obstructive coronary artery disease (MINOCA)." Russian Journal of Cardiology 30, no. 2 (2025): 5852. https://doi.org/10.15829/1560-4071-2025-5852.

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Aim. To assess the main parameters of transthoracic echocardiography, including the global function index in patients with myocardial infarction with obstructive (MICAD) and non-obstructive coronary artery disease (MINOCA).Material and methods. The study included 170 patients with a diagnosis of myocardial infarction were hospitalized and underwent inpatient treatment at the Cardiology Department № 1 of the Republican Clinical and Diagnostic Center, Izhevsk. Coronary angiography was performed on a Phillips Allure Clarity system. Based on the procedure results, the patients were divided into 2

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Bombardini, Tonino, Angela Zagatina, Quirino Ciampi, et al. "Hemodynamic Heterogeneity of Reduced Cardiac Reserve Unmasked by Volumetric Exercise Echocardiography." Journal of Clinical Medicine 10, no. 13 (2021): 2906. http://dx.doi.org/10.3390/jcm10132906.

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Background: Two-dimensional volumetric exercise stress echocardiography (ESE) provides an integrated view of left ventricular (LV) preload reserve through end-diastolic volume (EDV) and LV contractile reserve (LVCR) through end-systolic volume (ESV) changes. Purpose: To assess the dependence of cardiac reserve upon LVCR, EDV, and heart rate (HR) during ESE. Methods: We prospectively performed semi-supine bicycle or treadmill ESE in 1344 patients (age 59.8 ± 11.4 years; ejection fraction = 63 ± 8%) referred for known or suspected coronary artery disease. All patients had negative ESE by wall mo

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Rastogi, Sharad, Makoto Imai, Victor G. Sharov, Sudhish Mishra та Hani N. Sabbah. "Darbepoetin-α prevents progressive left ventricular dysfunction and remodeling in nonanemic dogs with heart failure". American Journal of Physiology-Heart and Circulatory Physiology 295, № 6 (2008): H2475—H2482. http://dx.doi.org/10.1152/ajpheart.00074.2008.

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In anemic patients with heart failure (HF), erythropoietin-type drugs can elicit clinical improvement. This study examined the effects of chronic monotherapy with darbepoetin-α (DARB) on left ventricular (LV) function and remodeling in nonanemic dogs with advanced HF. HF [LV ejection fraction (EF) ∼25%] was produced in 14 dogs by intracoronary microembolizations. Dogs were randomized to once a week subcutaneous injection of DARB (1.0 μg/kg, n = 7) or to no therapy (HF, n = 7). All procedures were performed during cardiac catheterization under general anesthesia and under sterile conditions. LV

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Nobrega, A. C., J. W. Williamson, and J. H. Mitchell. "Left ventricular volumes and hemodynamic responses at onset of dynamic exercise with reduced venous return." Journal of Applied Physiology 79, no. 5 (1995): 1405–10. http://dx.doi.org/10.1152/jappl.1995.79.5.1405.

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The hemodynamic effects of reducing venous return were assessed beat by beat at the onset of upright dynamic exercise. Mean arterial pressure (MAP), heart rate, and left ventricular end-systolic (ESV) and end-diastolic volumes (EDV; two-dimensional echocardiography) were measured in 10 healthy men during 20-s trials of upright cycling (30 W; 60 rpm). Exercise was performed either with or without venous occlusion of the legs (bilateral thigh cuffs inflated to 100 mmHg) in a random order. Without venous occlusion, MAP and cardiac output (CO) increased, and total peripheral resistance (TPR) decre

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Detombe, Sarah A., Fu-Li Xiang, Joy Dunmore-Buyze, James A. White, Qingping Feng, and Maria Drangova. "Rapid microcomputed tomography suggests cardiac enlargement occurs during conductance catheter measurements in mice." Journal of Applied Physiology 113, no. 1 (2012): 142–48. http://dx.doi.org/10.1152/japplphysiol.00831.2011.

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Conductance catheters (CC) represent an established method of determining cardiac function in mice; however, the potentially detrimental effects a catheter may have on the mouse heart have never been evaluated. The present study takes advantage of rapid three-dimensional (3D) microcomputed tomography (CT) to compare simultaneously acquired micro-CT and CC measurements of left ventricular (LV) volumes in healthy and infarcted mice and to determine changes in LV volume and function associated with CC insertion. LV volumes were measured in C57BL/6 mice (10 healthy, 10 infarcted, 2% isoflurane ane

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van der Linden, L. P., E. T. van der Velde, H. C. van Houwelingen, A. V. Bruschke, and J. Baan. "Determinants of end-systolic pressure during different load alterations in the in situ left ventricle." American Journal of Physiology-Heart and Circulatory Physiology 267, no. 5 (1994): H1895—H1906. http://dx.doi.org/10.1152/ajpheart.1994.267.5.h1895.

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Because of the strong dependency of the end-systolic pressure-volume relation on the type of transient loading intervention in the in situ left ventricle (LV), experiments in the basal inotropic state in 16 open-chest anesthetized dogs were reanalyzed to find additional variables to model and predict end-systolic pressure (ESP) of both afterloading and preloading interventions by a single equation. Random-coefficients regression analysis was performed on 22 experiments in the basal inotropic state simultaneously, yielding an overall R2 of 0.97. The major part of total variance of ESP was due t

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Ahmed, Amal Hafez, Amr ELHadidy, Mohamed Helmy, Ashraf Hussein, and Abdalla Elagha. "Myocardial Perfusion Grade by Coronary Angiography can Predict Final Infarct Size and Left Ventricular Function in Patients with ST-elevation Myocardial Infarction Treated with a Pharmaco-invasive Strategy." Open Access Macedonian Journal of Medical Sciences 9, B (2021): 184–90. http://dx.doi.org/10.3889/oamjms.2021.5815.

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BACKGROUND: Primary percutaneous coronary intervention (PCI) is the reperfusion strategy of choice in ST-elevation myocardial infarction (STEMI). Transfer for early angioplasty after thrombolytic therapy should be done without delay and has been directly related to improved patients’ outcome compared with thrombolysis alone. TIMI myocardial perfusion (TMP) grade provides important prognostic information for epicardial flow. AIM: We studied the relationship between TMP grade (at the end of the PCI procedure) and left ventricular ejection fraction (LVEF) and infarct size within 1 month in

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Visby, Lasse, Rasmus Møgelvang, Frederik Fasth Grund, et al. "The Influence of Food Intake and Preload Augmentation on Cardiac Functional Parameters: A Study Using Both Cardiac Magnetic Resonance and Echocardiography." Journal of Clinical Medicine 12, no. 21 (2023): 6781. http://dx.doi.org/10.3390/jcm12216781.

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(1) Background: To investigate how food intake and preload augmentation affect the cardiac output (CO) and volumes of the left ventricle (LV) and right ventricle (RV) assessed using cardiac magnetic resonance (CMR) and trans-thoracic echocardiography (TTE). (2) Methods: Eighty-two subjects with (n = 40) and without (n = 42) cardiac disease were assessed using both CMR and TTE immediately before and after a fast infusion of 2 L isotonic saline. Half of the population had a meal during saline infusion (food/fluid), and the other half were kept fasting (fasting/fluid). We analyzed end-diastolic (

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Fischer, R., B. Saurbier, I. Brink, E. Moser, T. Krause, and T. Zajic. "Assessment of left ventricular function and volumes by myocardial perfusion scintigraphy - comparison of two algorithms." Nuklearmedizin 40, no. 05 (2001): 135–42. http://dx.doi.org/10.1055/s-0038-1623878.

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Summary Aim: Left ventricular volume and function can be computed from gated SPECT myocardial perfusion imaging using Emory Cardiac Toolbox (ECT) or Gated SPECT Quantification (GS-Quant). The aim of this study was to compare both programs with respect to their practical application, stability and precision on heart-models as well as in clinical use. Methods: The volumes of five cardiac models were calculated by ECT and GS-Quant. 48 patients (13 female, 35 male) underwent a one day stress-rest protocol and gated SPECT. From these 96 gated SPECT images, left ventricular ejection fraction (LVEF),

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Claessen, Guido, Piet Claus, Marion Delcroix, Jan Bogaert, Andre La Gerche, and Hein Heidbuchel. "Interaction between respiration and right versus left ventricular volumes at rest and during exercise: a real-time cardiac magnetic resonance study." American Journal of Physiology-Heart and Circulatory Physiology 306, no. 6 (2014): H816—H824. http://dx.doi.org/10.1152/ajpheart.00752.2013.

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Breathing-induced changes in intrathoracic pressures influence left ventricular (LV) and right ventricular (RV) volumes, the exact nature and extent of which have not previously been evaluated in humans. We sought to examine this “respiratory pump” using novel real-time cardiac magnetic resonance (CMR) imaging. Eight healthy subjects underwent serial multislice real-time CMR during normal breathing, breath holding, and the Valsalva maneuver. Subsequently, a separate cohort of nine subjects underwent real-time CMR at rest and during incremental exercise. LV and RV end-diastolic volume (EDV) and

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Saleh, Muhammad G., Sarah-Kate Sharp, Alkathafi Alhamud, et al. "Long-Term Left Ventricular Remodelling in Rat Model of Nonreperfused Myocardial Infarction: Sequential MR Imaging Using a 3T Clinical Scanner." Journal of Biomedicine and Biotechnology 2012 (2012): 1–10. http://dx.doi.org/10.1155/2012/504037.

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Purpose. To evaluate whether 3T clinical MRI with a small-animal coil and gradient-echo (GE) sequence could be used to characterize long-term left ventricular remodelling (LVR) following nonreperfused myocardial infarction (MI) using semi-automatic segmentation software (SASS) in a rat model.Materials and Methods. 5 healthy rats were used to validate left ventricular mass (LVM) measured by MRI with postmortem values. 5 sham and 7 infarcted rats were scanned at 2 and 4 weeks after surgery to allow for functional and structural analysis of the heart. Measurements included ejection fraction (EF),

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Stöhr, Eric J., José González-Alonso, and Rob Shave. "Left ventricular mechanical limitations to stroke volume in healthy humans during incremental exercise." American Journal of Physiology-Heart and Circulatory Physiology 301, no. 2 (2011): H478—H487. http://dx.doi.org/10.1152/ajpheart.00314.2011.

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During incremental exercise, stroke volume (SV) plateaus at 40–50% of maximal exercise capacity. In healthy individuals, left ventricular (LV) twist and untwisting (“LV twist mechanics”) contribute to the generation of SV at rest, but whether the plateau in SV during incremental exercise is related to a blunting in LV twist mechanics remains unknown. To test this hypothesis, nine healthy young males performed continuous and discontinuous incremental supine cycling exercise up to 90% peak power in a randomized order. During both exercise protocols, end-diastolic volume (EDV), end-systolic volum

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Wang, Zirong, Tingting Song, and Da Yu. "Quantitative Assessment of Left Ventricular Function of Coronary Atherosclerotic Heart Disease with 640-Slice Dynamic Volume CT in Comparison to Echocardiography." Journal of Medical Imaging and Health Informatics 11, no. 5 (2021): 1378–83. http://dx.doi.org/10.1166/jmihi.2021.3385.

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Objective: The primary aim is to investigate the correlation between 640-slice dynamic volume computer tomography (DVCT) and echocardiography (ECHO) in the function of left ventricular (LV), and the value of DVCT in the evaluation of left coronary artery disease (LCA) and geometry and function of left ventricular, by measuring the difference of left ventricular function of coronary atherosclerotic heart disease with DVCT in comparison to ECHO. Materials and Methods: Sixty-three patients of coronary heart disease (CHD) with left coronary artery disease were selected, all of them were examined b

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Chiocchi, Marcello, Armando Ugo Cavallo, Luca Pugliese, et al. "Cardiac Computed Tomography Evaluation of Association of Left Ventricle Disfunction and Epicardial Adipose Tissue Density in Patients with Low to Intermediate Cardiovascular Risk." Medicina 59, no. 2 (2023): 232. http://dx.doi.org/10.3390/medicina59020232.

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Background and objectives: Epicardial adipose tissue density (EAD) has been associated with coronary arteries calcium score, a higher load of coronary artery disease (CAD) and plaque vulnerability. This effect can be related to endocrine and paracrine effect of molecules produced by epicardial adipose tissue (EAT), that may influence myocardial contractility. Using coronary computed tomography angiography (CCT) the evaluation of EAD is possible in basal scans. The aim of the study is to investigate possible associations between EAD and cardiac function. Material and Methods: 93 consecutive pat

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Denysiuk, K. V. "Optimisation of conservative treatment of patients with severe heart failure by using hemosorption." EMERGENCY MEDICINE 19, no. 8 (2024): 529–36. http://dx.doi.org/10.22141/2224-0586.19.8.2023.1643.

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Background. Heart failure (HF) is a complex cardiac pathology that is the main cause of hospitalisation among adults and is characterised by a high mortality. Dilated cardiomyopathy (DCM) is the most common cause of HF, and it can be fatal within a few years after the first symptoms appear. Many patients with HF remain refractory to medical therapy, despite its constant development and improvement. The study aims to compare the effectiveness of conservative treatment of patients with severe HF that occurred on the background of DCM using drug therapy and its combination with a course of hemoso

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Rastogi, Sharad, Victor G. Sharov, Sudhish Mishra, et al. "Ranolazine combined with enalapril or metoprolol prevents progressive LV dysfunction and remodeling in dogs with moderate heart failure." American Journal of Physiology-Heart and Circulatory Physiology 295, no. 5 (2008): H2149—H2155. http://dx.doi.org/10.1152/ajpheart.00728.2008.

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Acute intravenous infusion of ranolazine (Ran), an anti-ischemic/antiangina drug, was previously shown to improve left ventricular (LV) ejection fraction (EF) without a concomitant increase in myocardial oxygen consumption in dogs with chronic heart failure (HF). This study examined the effects of treatment with Ran alone and in combination with metoprolol (Met) or enalapril (Ena) on LV function and remodeling in dogs with HF. Dogs ( n = 28) with microembolization-induced HF were randomized to 3 mo oral treatment with Ran alone [375 mg twice daily (bid); n = 7], Ran (375 mg bid) in combination

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Yang, Chengzhi, Haobo Xu, Shubin Qiao, Ruofei Jia, Zening Jin, and Jiansong Yuan. "Papillary and Trabecular Muscles Have Substantial Impact on Quantification of Left Ventricle in Patients with Hypertrophic Obstructive Cardiomyopathy." Diagnostics 12, no. 8 (2022): 2029. http://dx.doi.org/10.3390/diagnostics12082029.

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Patients with obstructive hypertrophic cardiomyopathy (HOCM) have large papillary and trabecular muscles (PTMs), which are myocardial tissue. PTMs are usually excluded from the myocardium and included in the left ventricular (LV) cavity when determining LV mass (LVM) and volumes using cardiac magnetic resonance (CMR). This conventional method may result in large distortion of LVM and other indices. We investigated 74 patients with HOCM undergoing CMR imaging. LV short-axis cine images were obtained. LV contours were drawn using two different methods: (1) the conventional method, where PTMs wer

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Nita, Nicoleta, Johannes Kersten, Alexander Pott, et al. "Real-Time Spiral CMR Is Superior to Conventional Segmented Cine-Imaging for Left-Ventricular Functional Assessment in Patients with Arrhythmia." Journal of Clinical Medicine 11, no. 8 (2022): 2088. http://dx.doi.org/10.3390/jcm11082088.

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(1) Background: Segmented Cartesian Cardiovascular magnetic resonance (CMR) often fails to deliver robust assessment of cardiac function in patients with arrhythmia. We aimed to assess the performance of a tiny golden-angle spiral real-time CMR sequence at 1.5 T for left-ventricular (LV) volumetry in patients with irregular heart rhythm; (2) Methods: We validated the real-time sequence against the standard breath-hold segmented Cartesian sequence in 32 patients, of whom 11 presented with arrhythmia. End-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), and ejection fractio

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Shashkova, N. V., S. N. Tereshchenko, L. E. Samoylenko, D. F. Satlykova, and A. M. Gerasimov. "Effects of transluminal balloon angioplasty and stenting on the clinical course of ischemic chronic heart failure with preserved or reduced left ventricular ejection fraction: radionuclide 4D tomoventriculography data." Cardiovascular Therapy and Prevention 11, no. 1 (2012): 73–78. http://dx.doi.org/10.15829/1728-8800-2012-1-73-78.

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Aim. To study the effects of transluminal balloon angioplasty (TLBAP) and stenting on right and left ventricular (RV, LV) hemodynamics, as well as on long-term clinical prognosis, in patients with ischemic chronic heart failure (CHF). Material and methods. In 20 patients with ischemic CHF, Functional Class (FC) II–III (NYHA), radionuclide 4D tomoventriculography (4D-RTVG) was performed at baseline and 6 and 12 months after TLBAP, in order to assess cardiac hemodynamics. Based on ejection fraction (EF) values, all participants were divided into two groups. Group I (n=10; mean age 57,2 (2,7) yea

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Arslanoglu, Yavuz, Hayati Deniz, and Hasim Ustunsoy. "Comparison of Midterm and Long-Term Effects of Cord Protection Methods on Left Ventricular Function in Mitral Valve Replacement Surgery." ULUTAS MEDICAL JOURNAL 9, no. 1 (2023): 35. http://dx.doi.org/10.5455/umj.20230201114207.

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Introduction: Our study aimed to determine the effects of cord protection methods applied in Mitral valve replacement (MVR) surgery on left ventricular function. Materials and Methods: MVR surgery was performed on 634 patients using either single or combined procedures. Of these patients, 358 (56.5%) underwent conventional MVR surgery, 121 (19.1%) underwent total chordal protection, and 155 (24.4%) underwent posterior chordal preservation. All patients were evaluated as class 3 and 4 according to the New York functional classification (NYHA). Left ventricular diastolic end-diameter (SVDSD), le

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Bell, Stephen P., Judit Fabian, and Martin M. LeWinter. "Effects of dobutamine on left ventricular restoring forces." American Journal of Physiology-Heart and Circulatory Physiology 275, no. 1 (1998): H190—H194. http://dx.doi.org/10.1152/ajpheart.1998.275.1.h190.

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Restoring forces, which are generated when the left ventricle contracts below its equilibrium volume (Veq), are responsible for diastolic suction. Their magnitude is inversely related to end-systolic volume (ESV). In previous studies in which the mitral valve was replaced with a prosthesis, increased contractility was shown to augment restoring forces independently of ESV. In the present study, we quantified restoring forces in the presence of an intact mitral valve in open-chest dogs ( n = 6) as the fully relaxed pressure (FRP) after completion of left ventricular pressure (LVP) fall during n

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