Academic literature on the topic 'Endocrine disrupting chemicals in water – Toxicology'

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Journal articles on the topic "Endocrine disrupting chemicals in water – Toxicology"

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McGuire, Connor C., B. Paige Lawrence, and Jacques Robert. "Thyroid Disrupting Chemicals in Mixture Perturb Thymocyte Differentiation in Xenopus laevis Tadpoles." Toxicological Sciences 181, no. 2 (March 3, 2021): 262–72. http://dx.doi.org/10.1093/toxsci/kfab029.

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Abstract Endocrine disrupting chemicals (EDCs) can perturb the hypothalamic-pituitary-thyroid axis affecting human and wildlife health. Thyroid hormones (TH) are crucial regulators of metabolism, growth, and differentiation. The perinatal stage is most reliant on TH, thus vulnerable to TH disrupting chemicals. Dysregulation of TH signaling during perinatal development can weaken T cell function in maturity, raising the question of whether TH disrupting chemicals can perturb thymocyte development. Using Xenopus laevis tadpoles as model, we determined TH disrupting effects and thymocyte alterations following exposure to a mixture of common waterborne TH disrupting chemicals at concentrations similar to those found in contaminated water. This mixture included naphthalene, ethylene glycol, ethoxylated nonylphenol, and octylphenol, which have documented TH disrupting activity. Besides hypertrophy-like pathology in the thyroid gland and delayed metamorphosis, exposure to the mixture antagonized TH receptor-induced transcription of the Krüppel-like factor 9 transcription factor and significantly raised thyroid-stimulating hormone gene expression in the brain, two genes that modulate thymocyte differentiation. Importantly, exposure to this mixture reduced the number of Xenopus immature cortical thymocyte-specific-antigen (CTX+) and mature CD8+ thymocytes, whereas co-exposure with exogenous TH (T3) abolished the effect. When each chemical of the mixture was individually tested, only ethylene glycol induced significant antagonist effects on brain, thymic gene expression, and CD8+ thymocytes. These results suggest that EDCs in mixture are more potent than each chemical alone to perturb thymocyte development through TH-dependent pathway, and provide a starting point to research TH influence on thymocyte development.
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Húšková, Renáta, Eva Matisová, Silvia Ondreková, and Jarmila Ďurčanská. "Fast GC-MS of endocrine disrupting chemicals." International Journal of Environmental Analytical Chemistry 90, no. 3-6 (March 15, 2010): 173–87. http://dx.doi.org/10.1080/03067310902871273.

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Sun, Yan, Huang Huang, Ying Sun, Chao Wang, Xiao-Lei Shi, Hong-Ying Hu, Takashi Kameya, and Koichi Fujie. "Ecological risk of estrogenic endocrine disrupting chemicals in sewage plant effluent and reclaimed water." Environmental Pollution 180 (September 2013): 339–44. http://dx.doi.org/10.1016/j.envpol.2013.05.006.

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Radwan, Emad K., M. B. M. Ibrahim, Ahmed Adel, and Mohamed Farouk. "The occurrence and risk assessment of phenolic endocrine-disrupting chemicals in Egypt’s drinking and source water." Environmental Science and Pollution Research 27, no. 2 (November 22, 2019): 1776–88. http://dx.doi.org/10.1007/s11356-019-06887-0.

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Bradley, Paul M., William A. Battaglin, Luke R. Iwanowicz, Jimmy M. Clark, and Celeste A. Journey. "Aerobic biodegradation potential of endocrine‐disrupting chemicals in surface‐water sediment at Rocky Mountain National Park, USA." Environmental Toxicology and Chemistry 35, no. 5 (March 15, 2016): 1087–96. http://dx.doi.org/10.1002/etc.3266.

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Huang, Cong, Liu-Hong Wu, Guo-Qiang Liu, Lei Shi, and Ying Guo. "Occurrence and Ecological Risk Assessment of Eight Endocrine-Disrupting Chemicals in Urban River Water and Sediments of South China." Archives of Environmental Contamination and Toxicology 75, no. 2 (May 3, 2018): 224–35. http://dx.doi.org/10.1007/s00244-018-0527-9.

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Shao, Xiao-Ling, Jun Ma, Jing-Jing Yang, Xu-Chun Li, and Gang Wen. "Effect of humic acid on the oxidation of phenolic endocrine disrupting chemicals by permanganate." Journal of Water Supply: Research and Technology-Aqua 59, no. 5 (August 2010): 324–34. http://dx.doi.org/10.2166/aqua.2010.015.

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Wang, Song, Zeliang Zhu, Jiafa He, Xiaoya Yue, Jianxiong Pan, and Zaizhao Wang. "Steroidal and phenolic endocrine disrupting chemicals (EDCs) in surface water of Bahe River, China: Distribution, bioaccumulation, risk assessment and estrogenic effect on Hemiculter leucisculus." Environmental Pollution 243 (December 2018): 103–14. http://dx.doi.org/10.1016/j.envpol.2018.08.063.

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Zhang, Yi-zhang, Wei Meng, and Yuan Zhang. "Occurrence and Partitioning of Phenolic Endocrine-Disrupting Chemicals (EDCs) Between Surface Water and Suspended Particulate Matter in the North Tai Lake Basin, Eastern China." Bulletin of Environmental Contamination and Toxicology 92, no. 2 (November 1, 2013): 148–53. http://dx.doi.org/10.1007/s00128-013-1136-y.

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Shen, Yang, Dongdong Kong, Yanguo Teng, Yafei Wang, and Jian Li. "An assessment of the presence and health risks of endocrine-disrupting chemicals in the drinking water treatment plant of Wu Chang, China." Human and Ecological Risk Assessment: An International Journal 24, no. 4 (January 29, 2018): 1127–37. http://dx.doi.org/10.1080/10807039.2017.1407631.

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Dissertations / Theses on the topic "Endocrine disrupting chemicals in water – Toxicology"

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Chivers, Alicia M. "Investigating the Effects of 17α-Ethynylestradiol on Mitochondrial Genome Stability." PDXScholar, 2016. http://pdxscholar.library.pdx.edu/open_access_etds/2989.

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Environmental toxicants are ubiquitous throughout the environment as a result of human activity. Among these toxicants, environmental estrogens are a category of particular concern due to their environmental prevalence and potency in altering reproductive traits. While many studies have addressed the detrimental effects of environmental estrogens on both aquatic and terrestrial organisms, few have analyzed the potential for these compounds to alter mitochondrial function. Mitochondria are the primary energy-generating system for all eukaryotic life, supporting all aspects of development, metabolism, and growth. Each cell within the body contains many mitochondria which in turn contain multiple copies of their own DNA genome, mitochondrial DNA (mtDNA). Mutations in mtDNA are responsible for a wide range of human diseases such as metabolic syndromes, cancers, and obesity. Among these mitochondrial diseases many are characterized by increased levels of heteroplasmy, multiple mitochondrial DNA haplotypes within an individual. Increased heteroplasmy can alter normal mitochondrial function and influence disease initiation and progression. To date, no studies have investigated the effects of synthetic estrogens on mitochondrial genome stability. Synthetic estrogens have the capacity to bind to estrogen receptors and initiate estrogenic responses through translocation into the mitochondrion. Despite our knowledge about the relationship of heteroplasmy and disease, we still do not have a complete grasp of the mechanisms of heteroplasmic induction. Here we report our analysis of the effects of 17α-ethynylestradiol (EE2) exposure in three studies to investigate its effect on mitochondrial genome stability. Data analysis reveals a statistically significant relationship between EE2 exposure and increased heteroplasmic frequency.
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Ifelebuegu, A. O. "Removal of endocrine disrupting chemicals in wastewater treatment applications." Thesis, Coventry University, 2013. http://curve.coventry.ac.uk/open/items/2f9cce20-314e-42ee-8971-edb7304f8b42/1.

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This critical overview document (COD) presents, discusses and brings together the selected portfolio of publications that the author believes make a significant contribution to the field of wastewater treatment, focusing on the removal of endocrine disrupting chemicals (EDCs) in wastewater treatment applications. The aim of the research within this COD was to investigate the fate, mechanisms and optimisation of EDCs removal in wastewater treatment applications. The key objectives were to: 1. Investigate and understand the mechanisms of removal of EDCs in wastewater and sludge treatment processes. 2. Evaluate novel methods for the removal of EDCs in water and wastewater treatment applications. 3. Establish the kinetic and thermodynamic properties of the removal processes to inform process modelling of full scale design of treatment processes.
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Dann, Andrea B. "The effects of triclosan, 2,4-D, and their by-products on the adrenocortical cells of rainbow trout." Thesis, Lethbridge, Alta. : University of Lethbridge, Dept. of Biological Sciences, c2011, 2011. http://hdl.handle.net/10133/3154.

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The ubiquitous presence of anthropogenic chemicals and their transformation products in surface water represents a toxicological concern from both an ecological standpoint and a human perspective as many of these chemicals are capable of altering hormonal function. Endocrine disrupting compounds can be traced back to numerous sources and may fall under the class of pesticide, industrial chemical, pharmaceutical, personal care product, and/or heavy metals. The adrenal gland is the most common target for endocrine disruptors, although in comparison to the sex steroids, this system has received much less attention in published research. Corticosteroids play a pivotal role in many physiological processes, including immunity, cognitive function, growth, metabolism, reproduction, mineral balance, and blood pressure. A primary cell culture of rainbow trout adrenocortical cells was used to investigate the endocrine disrupting activity of two commonly detected water-borne toxicants, a personal care product, triclosan (TCS), a pesticide, dichlorophenoxyacetic acid (2,4-D), and their transformation products, methyl-triclosan (M-TCS) and dichlorophenol (DCP). Previously, it has been shown that TCS, 2,4-D, and DCP exhibit a potential for endocrine disruption, although it is currently unknown if these chemicals are capable of affecting corticosteroid balance. In this study, all four chemicals showed significant inhibitory effects on corticosteroid synthesis, even though there were considerable differences in their activity. The chemical that exhibited the highest toxicity was 2,4-D, followed by TCS, DCP, and M-TCS. Both parent-compounds proved to be more toxic than their degradation products. More research with suitable test systems is needed to determine the mechanism(s) of action of these corticosteroid disruptors and the health risk that they may present.
ix, 139 leaves : ill. ; 29 cm
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Jones, Maren Bell. "Effects and interactions of endocrine disrupting chemicals and diet on the mouse reproductive system." Diss., Columbia, Mo. : University of Missouri-Columbia, 2007. http://hdl.handle.net/10355/5006.

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Thesis (M.A.)--University of Missouri-Columbia, 2007.
The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from title screen of research.pdf file (viewed on October 29, 2007) Vita. Includes bibliographical references.
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Aneck-Hahn, NH, Jager C. de, MS Bornman, and Toit D. du. "Oestrogenic activity using a recombinant yeast screen assay (RCBA) in South African laboratory water sources." Water SA, 2005. http://encore.tut.ac.za/iii/cpro/DigitalItemViewPage.external?sp=1000932.

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Many chemicals released into the environment are believed to disrupt normal endocrine functions in humans and animals. These endocrine disrupting chemicals (EDCs) affect reproductive health and development. A major group of EDCs that could be responsible for reproductive effects are those that mimic natural oestrogens, known as xeno-oestrogens. A number of in vivo and in vitro screening strategies are being developed to identify and classify xeno-oestrogens, in order to determine whether they pose a health risk to humans and animals. It is also important to be able to apply the assays to environmental samples for monitoring purposes. In South Africa information on the levels of EDCs in water is limited. While establishing the recombinant yeast screen bioassay (RCBA) using the yeast strain Sacchyromyces cerivisiae for oestrogenic activity, problems were experienced with contamination. Four South African laboratory water sources were assessed. From the results it was clear that the water used in the preparation of the medium for the assay was the source of oestrogenic contamination. Care should be taken to eliminate all possible sources of contamination in the test procedures to eliminate the reporting of false positive results. The fact that South African laboratory and surface waters tested positive for estrogenic activity has far reaching implications regarding reproductive and general health.
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Sen, Sumitra. "Cellular and Molecular Effects of Mono-(2-ethylhexyl) phthalate (MEHP) in Testicular Cancer." Thesis, Université d'Ottawa / University of Ottawa, 2017. http://hdl.handle.net/10393/36844.

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Phthalates are endocrine-disrupting chemicals (EDCs) that are known testicular toxicants, used commonly as industrial plasticizers that are found in everyday items. Di-(2-ethylhexyl) phthalate (DEHP) is the most abundant phthalate in the environment, and its primary metabolite mono-(2-ethylhexyl) phthalate (MEHP) is ten-fold more potent. The purpose of this study is to examine the cellular and molecular effects of MEHP in the development of testicular cancer. Proliferation was measured for NT2 cells exposed to 10µM and 100µM MEHP at 24 and 48 hours and for cells under controlled conditions. Methylation-specific PCR (MSP) was used to determine the methylation status of the promoter region of key testicular genes post exposure to MEHP. MEHP caused a dose-dependent negative effect on proliferation and significantly altered methylation levels for key testicular genes following exposure to 10µM MEHP and 100µM, as compared to controls. This suggests that MEHP alters proliferation and methylation of testicular tumour cells in a time- and dose-dependent manner.
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Mohanty, Sanjay K. "Fate and transport of selected endocrine disrupting chemicals in recycled water through a tropical soil." Thesis, Water Resources Research Center, University of Hawaii at Manoa, 2006. http://hdl.handle.net/10125/20489.

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Simba, Hannah. "Optimisation and application of the GH3.TRE.Luc Reporter Gene Bioassay to assess thyroid activity in drinking and source water." Diss., University of Pretoria, 2017. http://hdl.handle.net/2263/61668.

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The endocrine system is vulnerable to a range of chemicals in the environment. Endocrine disrupting chemicals (EDCs) are exogenous agents that can induce responses on the endocrine system because of their hormone-like activity and toxicity. Specific to this study are thyroid disrupting chemicals (TDCs), these are EDCs that specifically disrupt the thyroid hormone signalling pathway, and this may result in adverse health effects. Thyroid hormones play a crucial part in metabolism, growth, maintenance of brain function and fertility; hence disruption of the thyroid signalling axis implicates human health. We are exposed to TDCs regularly, and studies have shown an association between TDC exposure and neurobehavioural disorders, reproductive abnormalities and obesity. There is a lack of data associated to thyroid hormone receptor activity in surface and drinking water. Hence, the potential human health risks posed by thyroid disruption may therefore be underestimated. The aim of the study was to optimise and validate the GH3.TRE.Luc reporter gene bioassay that can measure thyroid hormone receptor mediated activity and cytotoxicity in drinking and source water, with relevance to water monitoring. The GH3.TRE.Luc reporter gene bioassay was established, optimized and validated to detect thyroid hormone receptor activity. The luciferace assay was used to test for metabolic activity and the resazurine cell proliferation assay was used to assess cell viability. The assay was applied to compounds with agonistic and antagonistic properties; triidothyronine (T3), thyroxine (T4), triac, tetrac, amiodarone, sodium arsenite, pentachlorophenol (PCP), ethylene thiourea, 2,2,4,4-tetrahydroxybenzophenone (THBP) and methimazole. It was also applied to environmental and drinking water samples from the Global Water Research Coalition (GWRC). Finally, the assay was applied to 48 water samples from a water treatment plant in South Africa, collected over a period of 12 months. Every month, four samples were collected. Two samples were source water samples, with one going into the treatment plant and coming out as 2 distribution pipelines (drinking water). For optimisation and validation, the dose response curves obtained for T3, T4, tetrac and triac (agonists) were comparable to literature. Antagonistic behaviour was seen in sodium arsenite, amiodarone, PCP and methimazole. Spiked water samples from the GWRC showed thyroid hormone receptor activity. Sixteen of the 48 water samples collected from the water treatment plant were positive for thyroid hormone disruptor activity. Highest activity was seen in the winter season, accounting for seasonal variations. High TDCs activity reported in the source water may be due to activities occurring near the dam. The water treatment plant seemed effective for only one of the distribution pipelines, and not the other. This study confirms that GH3.TRE.Luc Reporter Gene Bioassay is a sensitive and effective tool to identify and quantify TDC activity in pure chemicals and in complex environmental mixtures present in water. Further monitoring of water sources for TDCs is recommended to ensure water quality and safety.
Dissertation (MSc)--University of Pretoria, 2017.
School of Health Systems and Public Health (SHSPH)
MSc
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Jones, Rebecca. "Bisphenol A and Bisphenol AF Potentiate Endometriosis Differently Based on Hormonal Status in Female Mice and Disrupt Normal Ovarian Function." University of Cincinnati / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1523635547444359.

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Kwekel, Joshua Caleb. "Cross-species comparison of estrogenic endocrine disruptor-induced, uterotrophic gene expression in the rodent." Diss., Connect to online resource - MSU authorized users, 2008.

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Books on the topic "Endocrine disrupting chemicals in water – Toxicology"

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Snyder, Shane A. Toxicological relevance of EDCs and pharmaceuticals in drinking water. Denver, CO: Awwa Research Foundation, 2008.

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Linden, Karl G. Impact of UV and UV/H₂O₂ AOP on EDC activity in water. Denver, Colo: Awwa Research Foundation, 2007.

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Linden, Karl G. Impact of UV and UV/H₂O₂ AOP on EDC activity in water. Denver, Colo: Awwa Research Foundation, 2007.

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United States. Congress. House. Committee on Energy and Commerce. Subcommittee on Energy and Environment. Endocrine-disrupting chemicals in drinking water: Risks to human health and the environment : hearing before the Subcommittee on Energy and Environment of the Committee on Energy and Commerce, House of Representatives, One Hundred Eleventh Congress, second session, February 25, 2010. Washington: U.S. G.P.O., 2012.

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Gülden, Michael. Endocrinically active chemicals and their occurrence in surface waters. Berlin: Umweltbundesamt, 1998.

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United, States Cooperative State Research Education and Extension Service. Endocrine disrupting chemicals: ABC's of EDC's : results from a regional science forum for the Mid-Atlantic (November 2006). United States]: CSREES, 2007.

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Snyder, Shane A. State of knowledge of endocrine disruptors and pharmaceuticals in drinking water. Denver, CO: Awwa Research Foundation, 2008.

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Endocrine disruptors and puberty. New York, N.Y: Humana Press, 2012.

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Taiwan huan jing jiao yu xie hui, ed. Huan jing he er meng: Ren shi tou zou jian kang, po huai sheng tai de yuan xiong : su hua ji, shuang fen A, dai ao xin, ren ji fen, gong ... = Endocrine disrupting chemicals. Gaoxiong Shi: Taiwan huan jing jiao yu xie hui, 2017.

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Endocrine Disrupters: Hazard Testing and Assessment Methods. New York, USA: Wiley, 2013.

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Book chapters on the topic "Endocrine disrupting chemicals in water – Toxicology"

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Preston, M. R. "Endocrine-Disrupting Chemicals in Marine Environment." In Chemistry of Marine Water and Sediments, 309–24. Berlin, Heidelberg: Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/978-3-662-04935-8_13.

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Chung, Felicia Fei-Lei, Rita Khoueiry, and Zdenko Herceg. "Chapter 2. Epigenetic Reprogramming by Endocrine Disrupting Chemicals." In Issues in Toxicology, 25–66. Cambridge: Royal Society of Chemistry, 2020. http://dx.doi.org/10.1039/9781839160738-00025.

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Raisuddin, S., and Shikha Sharma. "Endocrine-disrupting chemicals in food and their toxicological implications." In Food Toxicology, 199–250. Toronto ; New Jersey: Includes bibliographical references and index.: Apple Academic Press, 2017. http://dx.doi.org/10.1201/9781315161075-8.

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Catone, T., L. Attias, and A. Mantovani. "Chapter 16. Endocrine Disrupting Chemicals in Clothing and Cosmetics." In Issues in Toxicology, 389–407. Cambridge: Royal Society of Chemistry, 2020. http://dx.doi.org/10.1039/9781839160738-00389.

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Darbre, P. D. "Environmental endocrine-disrupting chemicals and human health." In A handbook of environmental toxicology: human disorders and ecotoxicology, 214–32. Wallingford: CABI, 2020. http://dx.doi.org/10.1079/9781786394675.0214.

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Mantovani, Alberto. "Chapter 3. Issues for Hazard Characterization of Endocrine Disrupting Chemicals: The Use of Adverse Outcome Pathways." In Issues in Toxicology, 67–79. Cambridge: Royal Society of Chemistry, 2020. http://dx.doi.org/10.1039/9781839160738-00067.

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Barber, Larry B., Greg K. Brown, and Steven D. Zaugg. "Potential Endocrine Disrupting Organic Chemicals in Treated Municipal Wastewater and River Water." In ACS Symposium Series, 97–123. Washington, DC: American Chemical Society, 1999. http://dx.doi.org/10.1021/bk-2000-0747.ch007.

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Miyagawa, Shinichi, Ryohei Yatsu, Tamotsu Sudo, Katsuhide Igarashi, Jun Kanno, and Taisen Iguchi. "Irreversible Effects of Diethylstilbestrol on Reproductive Organs and a Current Approach for Epigenetic Effects of Endocrine Disrupting Chemicals." In Toxicology and Epigenetics, 357–64. Chichester, UK: John Wiley & Sons, Ltd, 2012. http://dx.doi.org/10.1002/9781118349045.ch18.

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Nelson, William, Ying-Xiong Wang, Gloria Sakwari, and Yu-Bin Ding. "Review of the Effects of Perinatal Exposure to Endocrine-Disrupting Chemicals in Animals and Humans." In Reviews of Environmental Contamination and Toxicology, 131–84. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/398_2019_30.

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Cheng, Rong, Mi Kang, Lei Shi, Jin-lin Wang, Xiang Zheng, and Jian-long Wang. "Fe-Based Nanomaterials for Removing the Environmental Endocrine Disrupting Chemicals in Water: A Review." In Environmental Nanotechnology Volume 5, 261–92. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-73010-9_7.

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Conference papers on the topic "Endocrine disrupting chemicals in water – Toxicology"

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Zheng, Guochen, Jingbo Zhang, Chongjun Zhang, and Zhaohan Zhang. "Research progress of Endocrine Disrupting Chemicals in water." In 2015 International Forum on Energy, Environment Science and Materials. Paris, France: Atlantis Press, 2015. http://dx.doi.org/10.2991/ifeesm-15.2015.292.

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Zheng Yong-hong, Zhang Zhi-guo, Gao Liang-min, and Yao Duo-xi. "The study of endocrine disrupting chemicals in waterplant." In 2011 International Symposium on Water Resource and Environmental Protection (ISWREP). IEEE, 2011. http://dx.doi.org/10.1109/iswrep.2011.5893246.

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Wang, Xinze, Jiaming Lu, Natacha Ollivier, Anais Saturnino, Elena Gomez, Claude Casellas, Bernadette Picot, Fangming Jin, Qi Zhou, and Bing Wu. "Behavior of Selected Endocrine Disrupting Chemicals in Sewage Treatment Plant." In 2nd International Symposium on Aqua Science, Water Resource and Low Carbon Energy. AIP, 2010. http://dx.doi.org/10.1063/1.3529261.

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Zhou, Yunhe, Xiaodong Cheng, Leilei Wang, Guopu Wang, and Yong Huang. "Effect of Endocrine Disrupting Chemicals in Water Environment on Adolescent Idiopathic Scoliosis." In 2010 4th International Conference on Bioinformatics and Biomedical Engineering (iCBBE). IEEE, 2010. http://dx.doi.org/10.1109/icbbe.2010.5516586.

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Snyder, Erin M., Gretchen M. Bruce, Richard C. Pleus, and Shane A. Snyder. "Incidence and Toxicological Significance of Selected Endocrine Disrupting Chemicals (EDCs) in Drinking Water." In World Environmental and Water Resources Congress 2007. Reston, VA: American Society of Civil Engineers, 2007. http://dx.doi.org/10.1061/40927(243)140.

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Gonza´lez, Camille, Anai´s Va´zquez, Angel Morales, Liz Di´az, Carlos R. Cabrera, and Kai Griebenow. "Development of a Peroxidase Biosensor for the Detection of Endocrine Disrupting Chemicals (EDCs)." In ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology. ASMEDC, 2010. http://dx.doi.org/10.1115/nemb2010-13059.

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Endocrine disruptor compounds are able to mimic or antagonize the effects of endogenous hormones. Phenolic compounds are one of the most abundant classes of endocrine disruptors due to their presence in a broad range of chemical manufacturing processes. The detection of such compounds in food, medicine, and the environment (i.e., water) is crucial to ensure their quality. To prevent the noxious effects of endocrine disruptors an efficient monitoring system is required in order for immediate remediation to be activated. The long-term goal of the project is to develop a robust and stable amperometric enzyme based biosensor able to determine the concentration of phenolic endocrine disruptors. This type of biosensor can be useful to monitor endocrine distruptors in biological fluids and environmental samples as for example the spacecraft drinking water, to ensure the health of the astronauts in space.
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Weisheng Guan, Jianjun Yang, and Ping Lu. "Study on water quality criteria of Endocrine disrupting chemicals in Weihe River based on species sensitivity distributions theory." In 2011 International Symposium on Water Resource and Environmental Protection (ISWREP). IEEE, 2011. http://dx.doi.org/10.1109/iswrep.2011.5893217.

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VITO, DOMENICO. "A biosensored spatial data infrastructure for the dynamic monitoring of the presence and the activity of endocrine disrupting chemicals in water." In Third International Conference on Advances in Bio-Informatics and Environmental Engineering - ICABEE 2015. Institute of Research Engineers and Doctors, 2015. http://dx.doi.org/10.15224/978-1-63248-078-1-91.

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Linder, Greg, and Edward E. Little. "Competing Risks and the Development of Adaptive Management Plans for Water Resources: Field Reconnaissance Investigation of Risks to Fishes and Other Aquatic Biota Exposed to Endocrine Disrupting Chemicals (EDCs) in Lake Mead, Nevada, USA." In World Environmental and Water Resources Congress 2009. Reston, VA: American Society of Civil Engineers, 2009. http://dx.doi.org/10.1061/41036(342)567.

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