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Dissertations / Theses on the topic 'Endocrine disrupting chemicals in water – Toxicology'

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1

Chivers, Alicia M. "Investigating the Effects of 17α-Ethynylestradiol on Mitochondrial Genome Stability". PDXScholar, 2016. http://pdxscholar.library.pdx.edu/open_access_etds/2989.

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Environmental toxicants are ubiquitous throughout the environment as a result of human activity. Among these toxicants, environmental estrogens are a category of particular concern due to their environmental prevalence and potency in altering reproductive traits. While many studies have addressed the detrimental effects of environmental estrogens on both aquatic and terrestrial organisms, few have analyzed the potential for these compounds to alter mitochondrial function. Mitochondria are the primary energy-generating system for all eukaryotic life, supporting all aspects of development, metab
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2

Ifelebuegu, A. O. "Removal of endocrine disrupting chemicals in wastewater treatment applications." Thesis, Coventry University, 2013. http://curve.coventry.ac.uk/open/items/2f9cce20-314e-42ee-8971-edb7304f8b42/1.

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This critical overview document (COD) presents, discusses and brings together the selected portfolio of publications that the author believes make a significant contribution to the field of wastewater treatment, focusing on the removal of endocrine disrupting chemicals (EDCs) in wastewater treatment applications. The aim of the research within this COD was to investigate the fate, mechanisms and optimisation of EDCs removal in wastewater treatment applications. The key objectives were to: 1. Investigate and understand the mechanisms of removal of EDCs in wastewater and sludge treatment process
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3

Dann, Andrea B. "The effects of triclosan, 2,4-D, and their by-products on the adrenocortical cells of rainbow trout." Thesis, Lethbridge, Alta. : University of Lethbridge, Dept. of Biological Sciences, c2011, 2011. http://hdl.handle.net/10133/3154.

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The ubiquitous presence of anthropogenic chemicals and their transformation products in surface water represents a toxicological concern from both an ecological standpoint and a human perspective as many of these chemicals are capable of altering hormonal function. Endocrine disrupting compounds can be traced back to numerous sources and may fall under the class of pesticide, industrial chemical, pharmaceutical, personal care product, and/or heavy metals. The adrenal gland is the most common target for endocrine disruptors, although in comparison to the sex steroids, this system has received m
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4

Jones, Maren Bell. "Effects and interactions of endocrine disrupting chemicals and diet on the mouse reproductive system." Diss., Columbia, Mo. : University of Missouri-Columbia, 2007. http://hdl.handle.net/10355/5006.

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Thesis (M.A.)--University of Missouri-Columbia, 2007.<br>The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from title screen of research.pdf file (viewed on October 29, 2007) Vita. Includes bibliographical references.
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5

Aneck-Hahn, NH, Jager C. de, MS Bornman, and Toit D. du. "Oestrogenic activity using a recombinant yeast screen assay (RCBA) in South African laboratory water sources." Water SA, 2005. http://encore.tut.ac.za/iii/cpro/DigitalItemViewPage.external?sp=1000932.

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Many chemicals released into the environment are believed to disrupt normal endocrine functions in humans and animals. These endocrine disrupting chemicals (EDCs) affect reproductive health and development. A major group of EDCs that could be responsible for reproductive effects are those that mimic natural oestrogens, known as xeno-oestrogens. A number of in vivo and in vitro screening strategies are being developed to identify and classify xeno-oestrogens, in order to determine whether they pose a health risk to humans and animals. It is also important to be able to apply the assays to envir
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6

Sen, Sumitra. "Cellular and Molecular Effects of Mono-(2-ethylhexyl) phthalate (MEHP) in Testicular Cancer." Thesis, Université d'Ottawa / University of Ottawa, 2017. http://hdl.handle.net/10393/36844.

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Phthalates are endocrine-disrupting chemicals (EDCs) that are known testicular toxicants, used commonly as industrial plasticizers that are found in everyday items. Di-(2-ethylhexyl) phthalate (DEHP) is the most abundant phthalate in the environment, and its primary metabolite mono-(2-ethylhexyl) phthalate (MEHP) is ten-fold more potent. The purpose of this study is to examine the cellular and molecular effects of MEHP in the development of testicular cancer. Proliferation was measured for NT2 cells exposed to 10µM and 100µM MEHP at 24 and 48 hours and for cells under controlled conditions. Me
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7

Mohanty, Sanjay K. "Fate and transport of selected endocrine disrupting chemicals in recycled water through a tropical soil." Thesis, Water Resources Research Center, University of Hawaii at Manoa, 2006. http://hdl.handle.net/10125/20489.

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8

Simba, Hannah. "Optimisation and application of the GH3.TRE.Luc Reporter Gene Bioassay to assess thyroid activity in drinking and source water." Diss., University of Pretoria, 2017. http://hdl.handle.net/2263/61668.

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The endocrine system is vulnerable to a range of chemicals in the environment. Endocrine disrupting chemicals (EDCs) are exogenous agents that can induce responses on the endocrine system because of their hormone-like activity and toxicity. Specific to this study are thyroid disrupting chemicals (TDCs), these are EDCs that specifically disrupt the thyroid hormone signalling pathway, and this may result in adverse health effects. Thyroid hormones play a crucial part in metabolism, growth, maintenance of brain function and fertility; hence disruption of the thyroid signalling axis implicates hum
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9

Jones, Rebecca. "Bisphenol A and Bisphenol AF Potentiate Endometriosis Differently Based on Hormonal Status in Female Mice and Disrupt Normal Ovarian Function." University of Cincinnati / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1523635547444359.

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10

Kwekel, Joshua Caleb. "Cross-species comparison of estrogenic endocrine disruptor-induced, uterotrophic gene expression in the rodent." Diss., Connect to online resource - MSU authorized users, 2008.

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11

Wei, Xi. "Environmental screening of endocrine-disrupting chemicals and biological characterization of their effects on reproductive health." HKBU Institutional Repository, 2011. http://repository.hkbu.edu.hk/etd_ra/1225.

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12

Arwood, Bryan Stuart. "The effectiveness of advanced oxidation techniques in degrading steroids in wastewater." Birmingham, Ala. : University of Alabama at Birmingham, 2010. https://www.mhsl.uab.edu/dt/2010m/arwood.pdf.

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13

Van, Zijl Catherina. "Estrogenic activity target endocrine disrupting chemical levels and potential health risks of bottled water and water from selected distribution points in Pretoria and Cape Town." Thesis, University of Pretoria, 2016. http://hdl.handle.net/2263/61675.

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Endocrine disrupting chemicals (EDCs) are ubiquitous in the environment and have been detected in drinking water. Although various water treatment processes can remove EDCs, chemicals can migrate from pipes that transport water and contaminate drinking water. Globally bottled water consumption is steadily rising as an alternative to tap water, but EDCs have also been detected in bottled water. Sources of EDCs in bottled water include contamination of the water source, contamination through the production process or the migration of EDCs from the packaging material. There is limited info
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14

Olujimi, Olanrewaju Olusoji. "The concentrations, distribution and health risk assessment of suspected endocrine disrupting chemicals (phenols, phthalates and heavy metals) in freshwater systems of Cape Town, South Africa." Thesis, Cape Peninsula University of Technology, 2012. http://hdl.handle.net/20.500.11838/2009.

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Thesis (DTech (Environmental Health))--Cape Peninsula University of Technology, 2012.<br>Environmental pollution with persistent organic chemicals and inorganic trace metals is an increasingly important issue. Recently, a variety of chemicals are introduced in a very large scale on the surface water network. The main pathway of these pollutants into the environment was identified as wastewater treatment plants (WWTPs). The extended use of chemicals in many product formulations and insufficient WWTPs has lead to an increase in the levels of the detected micro-pollutants wastewater effluent
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15

Ngcobo, Silindile. "The suitability of estrogen and androgen bioassays for the measurement of endocrine activity in different water matrices." Diss., University of Pretoria, 2017. http://hdl.handle.net/2263/63041.

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Endocrine disrupting chemicals (EDCs) are ubiquitous in the environment and their presence in water bodies is documented. They discharge into surface water (SW) unmonitored, posing a threat to both aquatic and terrestrial lives. This is a challenge as not all populations have access to treated drinking water (TDW). The EDC contaminated serves as a route of exposure, together with ineffective treatment plants. Given the complexity of the endocrine system, EDCs may mimic or antagonise natural hormones or disrupt their synthesis, metabolism and excretion. The associated health effects incl
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16

Peres, Mariana Rodrigues. "Remoção dos interferentes endócrinos 17 'alfa'-etinilestradiol, 17 'beta'-estradiol e 4-nonilfenol por adsorção em carvão ativado em pó em água de abastecimento público." [s.n.], 2011. http://repositorio.unicamp.br/jspui/handle/REPOSIP/258693.

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Orientador: Ricardo de Lima Isaac<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia Civil, Arquitetura e Urbanismo<br>Made available in DSpace on 2018-08-18T23:00:14Z (GMT). No. of bitstreams: 1 Peres_MarianaRodrigues_M.pdf: 4938252 bytes, checksum: e65c217dee0ac585f070316b2ec3fbda (MD5) Previous issue date: 2011<br>Resumo: Nas últimas décadas, verifica-se um crescente interesse científico a respeito dos potenciais adversos associados à exposição humana e animal aos interferentes endócrinos. A ocorrência de interferentes endócrinos em efluente de Estação
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17

De, Almeida Louise. "The effect of sewage effluent from De Beers marine diamond mining operations on the expression of cytochrome P450 (CYP1A) and vitellogenin (vtg)." Thesis, Rhodes University, 2013. http://hdl.handle.net/10962/d1009440.

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Sewage effluents disposed into the marine environment from De Beers Marine Namibia diamond mining vessels have the potential to cause endocrine disruptive effects in marine organisms. Endocrine disruption refers to the alteration of the normal functioning of the endocrine system and various chemicals have the ability to mimic hormones, effecting endogenous hormone synthesis, transport, receptor interaction and intracellular signaling. The potential endocrine disruptive effects, caused by the release of different types of sewage effluents into the ocean, on fish species is a concern due to the
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18

Bergamasco, Ana Marcela Di Dea. "Emprego de bioensaios para avaliação da atividade estrogênica em água para consumo humano e mananciais do Estado de São Paulo." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/9/9141/tde-21102015-143320/.

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Interferentes endócrinos (IE) são substâncias capazes de afetar o sistema endócrino causando danos à saúde. Os compostos estrogênicos são um tipo de IE que geram resposta biológica semelhante aos hormônios endógenos, chamada atividade estrogênica, são frequentemente encontrados no ambiente devido à poluição de origem antrópica e ineficiência de processos de tratamento de água e esgoto. O objetivo deste trabalho foi avaliar a atividade estrogênica de águas de mananciais e águas tratadas para abastecimento no Estado de São Paulo por meio de bioensaios. Foram utilizados dois métodos, baseados em
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19

Kromrey, Natalie A., and University of Lethbridge Faculty of Arts and Science. "The effects of wastewater treatment plant effluent and agricultural runoff on the reproductive systems of fathead minnow, Pimephales promelas." Thesis, Lethbridge, Alta. : University of Lethbridge, Dept. of Biological Sciences, c2009, 2009. http://hdl.handle.net/10133/2519.

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Endocrine disrupting compounds and pesticides have been detected in rivers and irrigation canals of Southern Alberta, a semiarid region with irrigation-dependent crop production, intensive livestock operations, and a growing human population. However, little is known about the effects of agricultural runoff or wastewater treatment plant (WWTP) effluent in Southern Alberta on fish. Reproductive effects of WWTP effluents from the cities of Lethbridge and Medicine Hat, as well as agricultural runoff in the Lethbridge Northern Irrigation District canals, were investigated in a field study with wil
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20

Céspedes, Sánchez Raquel. "Vigilancia ambiental de Compuestos Disruptores Endocrinos y otros contaminantes prioritarios en el medio acuático mediante técnicas cromatográficas y biológicas." Doctoral thesis, Universitat de Barcelona, 2019. http://hdl.handle.net/10803/666574.

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Los compuestos disruptores endocrinos (EDCs) son sustancias exógenas capaces de alterar las funciones del sistema endocrino y la regulación del desarrollo embrionario, y por consecuencia, con capacidad de provocar efectos adversos sobre la salud de un organismo o su progenie (WHO, 2012). Hay un aumento de preocupación no solo por la presencia de estos compuestos en el medio ambiente, sino por los efectos biológicos que pueden ejercer sobre la salud humana y de animales. Los EDCs pueden ser compuestos naturales y sintéticos Tienen diversos mecanismos de actuación y presentan características
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21

Steiner, Laure D. "A Study of the fate and transport of estrogenic hormones in dairy effluent applied to pasture soils." Diss., Lincoln University, 2009. http://hdl.handle.net/10182/1306.

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The disposal of waste from agricultural activities has been recognised as a source of environmental contamination by endocrine disrupting chemicals (EDCs). The New Zealand dairy industry produces a large volume of dairy farm effluent, which contains EDCs in the form of estrogens. Most of this dairy farm effluent is applied onto the land for disposal. Groundwater and soil contamination by estrogens following waste application on the land have been reported overseas, but our understanding of the processes and factors governing the fate of estrogens in the soil is poor. Therefore the main goal o
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22

Surujlal-Naicker, Swastika. "Detection and evaluation of the fate of estrogen endocrine disrupting chemicals in wastewater treatment." Thesis, 2014. http://hdl.handle.net/10321/1755.

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Submitted in fulfillment of the requirements for the degree of Doctorate of Technology: Biotechnology, Durban University of Technology, Durban, South Africa, 2014.<br>All over the world concerns have been raised over the possible adverse effects that may occur when exposed to chemicals that have the potential to interfere and affect the endocrine system. The concern is directed at both humans and wildlife. There is still a lack of public awareness regarding Endocrine Disrupting Chemicals (EDCs) and the harmful effects on humans and wildlife. It has only been within the last decade that South
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23

Osunmakinde, Cecilia Oluseyi. "Dispersive liquid-liquid micro-extraction of steroidal hormones and determination in wastewater using high pressure liquid chromatography: charged aerosol detector." Diss., 2014. http://hdl.handle.net/10500/19733.

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Steroid hormones belong to a group of compounds known as endocrine disruptors. They are hydrophobic compounds and are categorized as natural and synthetic estrogens. Some common household products have been implicated as estrogen mimics. Exposure effects of these compounds are felt by human and wildlife, such reproductive alterations in fish and frogs. They mainly introduced into the environment through veterinary medicines administration to animals and the discharges from wastewater treatment plants (WWTPs). In this study, a new alternative analytical procedure that is simple, rapid and fast
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24

Kwon, Jung-Hwan. "Bioavailability of endocrine disrupting chemicals (EDCs): liposome-water partitioning and lipid membrane permeation." Thesis, 2006. http://hdl.handle.net/2152/2753.

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25

Huang, Min-Hao, and 黃湣皓. "Green Solvent Ionic Liquid Microextraction Combination with HPLC Analysis of Endocrine Disrupting Chemicals in Water Samples." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/95330540987327069737.

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碩士<br>逢甲大學<br>環境工程與科學所<br>100<br>In recent years, many countries have gradually started to notice the important issue of endocrine disrupting chemicals (EDCs). In 1997, Japan first proposed 70 suspected EDCs and held the international conference of endocrine disrupting substances in 1998. The United States presented another endocrine disrupting chemicals screening program in 1998 and pointed out 87,000 chemicals to the research program of endocrine disrupting chemicals. Until recently, many countries including Taiwan have showed that great interesting of EDCs in the environment. in past dec
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Kruger, Taneshka. "Effects of endocrine disrupting chemicals on selected reproductive features of the male Sharptooth catfish (Clarias gariepinus)." Thesis, 2012. http://hdl.handle.net/10210/6227.

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D.Phil.<br>The endocrine system regulates important physiological processes in an organism. Numerous natural and synthetic chemicals are released into the environment and can disrupt the normal functioning of the endocrine system, influencing physiological processes even at relatively low concentrations. These chemicals are known as endocrine disrupting chemicals (EDCs). These compounds are highly persistent in nature due to a resistance to biodegradation, and because of their hydrophobicity. EDCs bio-accumulate especially in the fatty tissue of aquatic and terrestrial organisms. Developmental
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27

Seshoka, M. F. "Mancozeb in natural water sources in the Vhembe District and the possible endocrine disrupting activity/potential there-of." Diss., 2018. http://hdl.handle.net/11602/1205.

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MSc (Zoology)<br>Department of Zoology<br>Many chemicals released into the environment are believed to disrupt normal endocrine functions in humans and animals. These endocrine disrupting chemicals (EDCs) affect reproductive health and development. A major group of EDCs that could be responsible for reproductive effects are those that mimic natural oestrogens, known as xeno-oestrogens. A number of in vivo and in vitro screening strategies are being developed to identify and classify xeno-oestrogens, in order to determine whether they pose a health risk to humans and animals. It is also importa
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