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1

McGuire, Connor C., B. Paige Lawrence, and Jacques Robert. "Thyroid Disrupting Chemicals in Mixture Perturb Thymocyte Differentiation in Xenopus laevis Tadpoles." Toxicological Sciences 181, no. 2 (2021): 262–72. http://dx.doi.org/10.1093/toxsci/kfab029.

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Abstract Endocrine disrupting chemicals (EDCs) can perturb the hypothalamic-pituitary-thyroid axis affecting human and wildlife health. Thyroid hormones (TH) are crucial regulators of metabolism, growth, and differentiation. The perinatal stage is most reliant on TH, thus vulnerable to TH disrupting chemicals. Dysregulation of TH signaling during perinatal development can weaken T cell function in maturity, raising the question of whether TH disrupting chemicals can perturb thymocyte development. Using Xenopus laevis tadpoles as model, we determined TH disrupting effects and thymocyte alterati
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2

Húšková, Renáta, Eva Matisová, Silvia Ondreková, and Jarmila Ďurčanská. "Fast GC-MS of endocrine disrupting chemicals." International Journal of Environmental Analytical Chemistry 90, no. 3-6 (2010): 173–87. http://dx.doi.org/10.1080/03067310902871273.

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3

Sun, Yan, Huang Huang, Ying Sun, et al. "Ecological risk of estrogenic endocrine disrupting chemicals in sewage plant effluent and reclaimed water." Environmental Pollution 180 (September 2013): 339–44. http://dx.doi.org/10.1016/j.envpol.2013.05.006.

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4

Radwan, Emad K., M. B. M. Ibrahim, Ahmed Adel, and Mohamed Farouk. "The occurrence and risk assessment of phenolic endocrine-disrupting chemicals in Egypt’s drinking and source water." Environmental Science and Pollution Research 27, no. 2 (2019): 1776–88. http://dx.doi.org/10.1007/s11356-019-06887-0.

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5

Bradley, Paul M., William A. Battaglin, Luke R. Iwanowicz, Jimmy M. Clark, and Celeste A. Journey. "Aerobic biodegradation potential of endocrine‐disrupting chemicals in surface‐water sediment at Rocky Mountain National Park, USA." Environmental Toxicology and Chemistry 35, no. 5 (2016): 1087–96. http://dx.doi.org/10.1002/etc.3266.

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6

Huang, Cong, Liu-Hong Wu, Guo-Qiang Liu, Lei Shi, and Ying Guo. "Occurrence and Ecological Risk Assessment of Eight Endocrine-Disrupting Chemicals in Urban River Water and Sediments of South China." Archives of Environmental Contamination and Toxicology 75, no. 2 (2018): 224–35. http://dx.doi.org/10.1007/s00244-018-0527-9.

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7

Shao, Xiao-Ling, Jun Ma, Jing-Jing Yang, Xu-Chun Li, and Gang Wen. "Effect of humic acid on the oxidation of phenolic endocrine disrupting chemicals by permanganate." Journal of Water Supply: Research and Technology-Aqua 59, no. 5 (2010): 324–34. http://dx.doi.org/10.2166/aqua.2010.015.

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8

Wang, Song, Zeliang Zhu, Jiafa He, Xiaoya Yue, Jianxiong Pan, and Zaizhao Wang. "Steroidal and phenolic endocrine disrupting chemicals (EDCs) in surface water of Bahe River, China: Distribution, bioaccumulation, risk assessment and estrogenic effect on Hemiculter leucisculus." Environmental Pollution 243 (December 2018): 103–14. http://dx.doi.org/10.1016/j.envpol.2018.08.063.

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9

Zhang, Yi-zhang, Wei Meng, and Yuan Zhang. "Occurrence and Partitioning of Phenolic Endocrine-Disrupting Chemicals (EDCs) Between Surface Water and Suspended Particulate Matter in the North Tai Lake Basin, Eastern China." Bulletin of Environmental Contamination and Toxicology 92, no. 2 (2013): 148–53. http://dx.doi.org/10.1007/s00128-013-1136-y.

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10

Shen, Yang, Dongdong Kong, Yanguo Teng, Yafei Wang, and Jian Li. "An assessment of the presence and health risks of endocrine-disrupting chemicals in the drinking water treatment plant of Wu Chang, China." Human and Ecological Risk Assessment: An International Journal 24, no. 4 (2018): 1127–37. http://dx.doi.org/10.1080/10807039.2017.1407631.

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11

Swart, Johannes Cornelius, Edmund John Pool, and Johannes Hendrik van Wyk. "The implementation of a battery of in vivo and in vitro bioassays to assess river water for estrogenic endocrine disrupting chemicals." Ecotoxicology and Environmental Safety 74, no. 1 (2011): 138–43. http://dx.doi.org/10.1016/j.ecoenv.2010.09.006.

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12

Liu, Jingliang, Xuejun Pan, Bin Huang, Kai Fang, Yu Wang, and Jianpei Gao. "An improved method for simultaneous analysis of steroid and phenolic endocrine disrupting chemicals in biological samples." International Journal of Environmental Analytical Chemistry 92, no. 10 (2011): 1135–49. http://dx.doi.org/10.1080/03067319.2010.510604.

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13

Yang, Juan, King Ming Chan, and Jian Gong. "Seasonal variation and the distribution of endocrine-disrupting chemicals in various matrices affected by algae in the eutrophic water environment of the pearl river delta, China." Environmental Pollution 263 (August 2020): 114462. http://dx.doi.org/10.1016/j.envpol.2020.114462.

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14

Huang, Yu, Xianchuan Xie, Li Jun Zhou, et al. "Multi-phase distribution and risk assessment of endocrine disrupting chemicals in the surface water of the Shaying River, -Huai River Basin, China." Ecotoxicology and Environmental Safety 173 (May 2019): 45–53. http://dx.doi.org/10.1016/j.ecoenv.2019.02.016.

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15

Katić, Jelena, Aleksandra Fučić, and Marija Gamulin. "Prenatal, Early Life, and Childhood Exposure to Genotoxicants in the Living Environment." Archives of Industrial Hygiene and Toxicology 61, no. 4 (2010): 455–64. http://dx.doi.org/10.2478/10004-1254-61-2010-2065.

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Prenatal, Early Life, and Childhood Exposure to Genotoxicants in the Living EnvironmentHealth disorders and diseases related to environmental exposure in children such as cancer and immunologic disturbances (asthma, allergies) are on the rise. However, complex transplacental and prepubertal genotoxicology is given very limited consideration, even though intrauterine development and early childhood may be critical for elucidating the cancer aetiology. The foetus is transplacentally exposed to contaminants in food and environment such as various chemicals, drugs, radiochemically contaminated wat
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16

Li, Huan, Shihua Qi, Xiaoshui Li, Zhe Qian, Wei Chen та Shibin Qin. "Tetrafluoroterephthalonitrile-crosslinked β-cyclodextrin polymer as a binding agent of diffusive gradients in thin-films for sampling endocrine disrupting chemicals in water". Chemosphere 280 (жовтень 2021): 130774. http://dx.doi.org/10.1016/j.chemosphere.2021.130774.

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17

Loffredo, Elisabetta, Giuseppe Picca, and Marco Parlavecchia. "Single and combined use of Cannabis sativa L. and carbon-rich materials for the removal of pesticides and endocrine-disrupting chemicals from water and soil." Environmental Science and Pollution Research 28, no. 3 (2020): 3601–16. http://dx.doi.org/10.1007/s11356-020-10690-7.

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AbstractHemp (Cannabis sativa L.) seedlings were used to remove from water the fungicide metalaxyl-M and the endocrine disruptor (EDC) bisphenol A (BPA) at concentrations ranging from 2 to 100 μg mL−1. In 7 days of exposure, despite the phytotoxicity of each compound that reduced elongation and biomass, the seedlings were able to remove between 67 and 94% of metalaxyl-M and between 86 and 95% of BPA. The amounts of metalaxyl-M and BPA extracted from plant dry biomass were in the range of 106–3861 μg g−1 and 16–101 μg g−1, respectively, and resulted positively correlated to both the dose of com
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18

Stradtman, Sydney C., and Jennifer L. Freeman. "Mechanisms of Neurotoxicity Associated with Exposure to the Herbicide Atrazine." Toxics 9, no. 9 (2021): 207. http://dx.doi.org/10.3390/toxics9090207.

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Atrazine is an herbicide commonly used on crops to prevent broadleaf weeds. Atrazine is an endocrine-disrupting chemical mainly targeting the neuroendocrine system and associated axes, especially as a reproductive toxicant through attenuation of the luteinizing hormone (LH). Current regulatory levels for chronic exposure are based on no observed adverse effect levels (NOAELs) of these LH alterations in rodent studies. Atrazine has also been studied for its effects on the central nervous system and neurotransmission. The European Union (EU) recognized the health risks of atrazine exposure as a
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19

Sterrett, Mary E., Michael S. Bloom, Erica L. Jamro, et al. "Maternal Food and Beverage Consumption Behaviors and Discrepant Phthalate Exposure by Race." International Journal of Environmental Research and Public Health 18, no. 4 (2021): 2190. http://dx.doi.org/10.3390/ijerph18042190.

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Background: Differential exposure to endocrine-disrupting chemicals, including phthalate diesters, may contribute to persistent racial/ethnic disparities in women’s reproductive health outcomes. We sought to characterize sources of gestational exposure to these agents that may differ according to maternal race. Methods: We enrolled pregnant Black (n = 198), including African American, and White (n = 197) women during the second trimester, and measured eight phthalate monoester metabolites in urine. We assessed confounder-adjusted associations between multiple food and beverage consumption habi
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20

Luís, Catarina, Manuel Algarra, José S. Câmara, and Rosa Perestrelo. "Comprehensive Insight from Phthalates Occurrence: From Health Outcomes to Emerging Analytical Approaches." Toxics 9, no. 7 (2021): 157. http://dx.doi.org/10.3390/toxics9070157.

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Phthalates are a group of chemicals used in a multitude of important industrial products (e.g., medical devices, children’s toys, and food packages), mainly as plasticizers to improve mechanical properties such as flexibility, transparency, durability, and longevity of polyvinyl chloride (PVC). The wide occurrence of phthalates in many consumer products, including foods (e.g., bottled water, soft drinks, wine, milk, and meat) brings that most people are exposed to phthalates every day, which raises some concerns. Adverse health outcomes from phthalates exposure have been associated with endocr
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21

Üstündağ, Ünsal Veli, İsmail Ünal, Perihan Seda Ateş, A. Ata Alturfan, Türkan Yiğitbaşı та Ebru Emekli-Alturfan. "Bisphenol A and di(2-ethylhexyl) phthalate exert divergent effects on apoptosis and the Wnt/β-catenin pathway in zebrafish embryos: A possible mechanism of endocrine disrupting chemical action". Toxicology and Industrial Health 33, № 12 (2017): 901–10. http://dx.doi.org/10.1177/0748233717733598.

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Polyethylene terephthalate (PET) and polycarbonate (PC) are the most commonly used plastics in water bottles. Di(2-ethylhexyl) phthalate (DEHP) is used as a plasticizer in PET plastics, and bisphenol A (BPA) is used to produce PC. Both DEHP and BPA are known for their potential endocrine disrupting effects. The Wnt/β-catenin signaling pathway has important roles in cell proliferation, cell specification and cell fate determination during embryonic development. Recent reports suggest a link between the Wnt/β-catenin signaling pathway and apoptosis. The aim of this study was to investigate the r
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22

Roefer, Peggy, Shane Snyder, Ronald E. Zegers, David J. Rexing, and John L. Fronk. "Endocrine-disrupting chemicals in a source water." Journal - American Water Works Association 92, no. 8 (2000): 52–58. http://dx.doi.org/10.1002/j.1551-8833.2000.tb08992.x.

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23

Amato, Angelica Amorim, Hailey Brit Wheeler, and Bruce Blumberg. "Obesity and endocrine-disrupting chemicals." Endocrine Connections 10, no. 2 (2021): R87—R105. http://dx.doi.org/10.1530/ec-20-0578.

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Obesity is now a worldwide pandemic. The usual explanation given for the prevalence of obesity is that it results from consumption of a calorie dense diet coupled with physical inactivity. However, this model inadequately explains rising obesity in adults and in children over the past few decades, indicating that other factors must be important contributors. An endocrine-disrupting chemical (EDC) is an exogenous chemical, or mixture that interferes with any aspect of hormone action. EDCs have become pervasive in our environment, allowing humans to be exposed daily through ingestion, inhalation
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24

Yang, Changwon, Gwonhwa Song, and Whasun Lim. "Effects of endocrine disrupting chemicals in pigs." Environmental Pollution 263 (August 2020): 114505. http://dx.doi.org/10.1016/j.envpol.2020.114505.

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25

Adams, C., and A. Bhandari. "Endocrine Disrupting Chemicals in the Environment." Practice Periodical of Hazardous, Toxic, and Radioactive Waste Management 7, no. 4 (2003): 201. http://dx.doi.org/10.1061/(asce)1090-025x(2003)7:4(201).

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26

Alsen, Mathilda, Catherine Sinclair, Peter Cooke, Kimia Ziadkhanpour, Eric Genden, and Maaike van Gerwen. "Endocrine Disrupting Chemicals and Thyroid Cancer: An Overview." Toxics 9, no. 1 (2021): 14. http://dx.doi.org/10.3390/toxics9010014.

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Endocrine disruptive chemicals (EDC) are known to alter thyroid function and have been associated with increased risk of certain cancers. The present study aims to provide a comprehensive overview of available studies on the association between EDC exposure and thyroid cancer. Relevant studies were identified via a literature search in the National Library of Medicine and National Institutes of Health PubMed as well as a review of reference lists of all retrieved articles and of previously published relevant reviews. Overall, the current literature suggests that exposure to certain congeners o
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27

AKAMATSU, Yoshihisa, Syunsuke IKEDA, Seiichiro KANAI, Syuichi OSAWA, and Kazutoshi OSAWA. "PHYTOREMEDIATION OF ENDOCRINE DISRUPTING CHEMICALS IN URBAN RIVER WATER." Doboku Gakkai Ronbunshuu G 66, no. 4 (2010): 201–10. http://dx.doi.org/10.2208/jscejg.66.201.

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28

Fox, Jennifer E. "Chemical communication threatened by endocrine-disrupting chemicals." Environmental Health Perspectives 112, no. 6 (2004): 648–53. http://dx.doi.org/10.1289/ehp.6455.

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29

Nakamura, Kazuo, and Hiroko Kariyazono. "Influence of Endocrine-disrupting Chemicals on the Immune System." JOURNAL OF HEALTH SCIENCE 56, no. 4 (2010): 361–73. http://dx.doi.org/10.1248/jhs.56.361.

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30

Shrader, E. A., T. R. Henry, M. S. Greeley, and B. P. Bradley. "Proteomics in Zebrafish Exposed to Endocrine Disrupting Chemicals." Ecotoxicology 12, no. 6 (2003): 485–88. http://dx.doi.org/10.1023/b:ectx.0000003034.69538.eb.

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31

Gao, Xiufang, Shuang Kang, Rongwei Xiong, and Ming Chen. "Environment-Friendly Removal Methods for Endocrine Disrupting Chemicals." Sustainability 12, no. 18 (2020): 7615. http://dx.doi.org/10.3390/su12187615.

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In the past few decades, many emerging pollutants have been detected and monitored in different water sources because of their universal consumption and improper disposal. Among these, endocrine-disrupting chemicals (EDCs), a group of organic chemicals, have received global attention due to their estrogen effect, toxicity, persistence and bioaccumulation. For the removal of EDCs, conventional wastewater treatment methods include flocculation, precipitation, adsorption, etc. However, there are some limitations on these common methods. Herein, in order to enhance the public’s understanding of en
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32

YANG, MIHI, MI SEON PARK, and HO SUN LEE. "Endocrine Disrupting Chemicals: Human Exposure and Health Risks." Journal of Environmental Science and Health, Part C 24, no. 2 (2006): 183–224. http://dx.doi.org/10.1080/10590500600936474.

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33

Dang, ZhiChao. "Fish biomarkers for regulatory identification of endocrine disrupting chemicals." Environmental Pollution 185 (February 2014): 266–70. http://dx.doi.org/10.1016/j.envpol.2013.11.006.

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34

Mueller, Johanna K., and Sabine Heger. "Endocrine disrupting chemicals affect the Gonadotropin releasing hormone neuronal network." Reproductive Toxicology 44 (April 2014): 73–84. http://dx.doi.org/10.1016/j.reprotox.2013.10.011.

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35

Brescia, Susy. "Thresholds of adversity and their applicability to endocrine disrupting chemicals." Critical Reviews in Toxicology 50, no. 3 (2020): 213–18. http://dx.doi.org/10.1080/10408444.2020.1740973.

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36

Sutcliffe, Roger. "Endocrine Disrupting Substances and Ecological Risk Assessment of Commercial Chemicals in Canada." Water Quality Research Journal 36, no. 2 (2001): 303–17. http://dx.doi.org/10.2166/wqrj.2001.018.

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Abstract The ecological risk assessment of commercial chemicals in Canada by the regulatory programs of the Commercial Chemicals Evaluation Branch, Environment Canada, are based on results from traditional toxicity data (e.g., lethality, effects to growth or reproduction). Some of the chemicals under consideration are known to alter endocrine systems in exposed organisms; however, effects to the endocrine system are used only as additional supporting information. Presently, there are no internationally accepted methodologies or tests for endocrine disrupting substances that can be used by thes
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37

NAKAMURO, Katsuhiko, Hitoshi UENO, Tomofumi OKUNO, et al. "Contribution of Endocrine-Disrupting Chemicals to Estrogenicity of Environmental Water." Journal of Japan Society on Water Environment 25, no. 6 (2002): 355–60. http://dx.doi.org/10.2965/jswe.25.355.

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38

Metzler, M., E. Pfeiffer, and A. Hildebrand. "Zearalenone and its metabolites as endocrine disrupting chemicals." World Mycotoxin Journal 3, no. 4 (2010): 385–401. http://dx.doi.org/10.3920/wmj2010.1244.

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Zearalenone (ZEA) is a macrocyclic β-resorcylic acid lactone produced by numerous species of Fusarium. It frequently contaminates corn and cereal products in many regions of the world. The biological activity of ZEA is dominated by its pronounced oestrogenicity, which is even enhanced in certain reductive metabolites. This review updates the metabolism in fungi, plants and mammalian systems, as well as the pharmacokinetics of ZEA. The present evidence for the hormonal effects of the parent mycoestrogen and some of its metabolites in vitro and in farm and experimental animals in vivo is reviewe
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39

Jeung, Eui-Bae, and Kyung-Chul Choi. "Toxicological Mechanism of Endocrine Disrupting Chemicals: Is Estrogen Receptor Involved?" Toxicological Research 26, no. 4 (2010): 237–43. http://dx.doi.org/10.5487/tr.2010.26.4.237.

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40

Lin, Ying Zi, Chang Hu Cao, Jun Yin, and Wu Chao. "Investigation of Endocrine Disrupting Chemicals in a Sewage Treatment Plant of Changchun in Frozen Period." Advanced Materials Research 281 (July 2011): 309–12. http://dx.doi.org/10.4028/www.scientific.net/amr.281.309.

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For low-temperature conditions, the municipal sewage plant on the low removal efficiency of endocrine disrupting chemicals, We are the investigation of endocrine disrupting chemicals in a sewage plant of Changchun City. The results showed that the water contains contaminants 2,4,6-Tris[Bis(Methoxymethyl)Amino]-1,3,5-Triazine, the substance is endocrine disruptors chemicals, it is more harmful to the environment. In addition, Out of the water contains Triethylphosphate, it is the metabolites of organ phosphorus pesticides, it also has a greater impact on the environment, they should be targeted
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41

Corton, J. Christopher, Nicole C. Kleinstreuer, and Richard S. Judson. "Identification of potential endocrine disrupting chemicals using gene expression biomarkers." Toxicology and Applied Pharmacology 380 (October 2019): 114683. http://dx.doi.org/10.1016/j.taap.2019.114683.

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42

Yawer, Affiefa, Eliška Sychrová, Petra Labohá, et al. "Endocrine-disrupting chemicals rapidly affect intercellular signaling in Leydig cells." Toxicology and Applied Pharmacology 404 (October 2020): 115177. http://dx.doi.org/10.1016/j.taap.2020.115177.

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43

Hirose, Masao, Akiyoshi Nishikawa, Makoto Shibutani, and Kunitoshi Mitsumori. "Environmental Agents, Endocrine Disrupting Chemicals and Rat Thyroid Carcinogenesis." Journal of Toxicologic Pathology 14, no. 1 (2001): 71. http://dx.doi.org/10.1293/tox.14.71.

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44

Chen, Hao, Zhaoping Liu, Xiaopeng Zhang, et al. "Assessment of synergistic thyroid disrupting effects of a mixture of EDCs in ovariectomized rats using factorial analysis and dose addition." Toxicology Research 5, no. 6 (2016): 1585–93. http://dx.doi.org/10.1039/c6tx00193a.

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45

Hamid, Naima, Muhammad Junaid, and De-Sheng Pei. "Combined toxicity of endocrine-disrupting chemicals: A review." Ecotoxicology and Environmental Safety 215 (June 2021): 112136. http://dx.doi.org/10.1016/j.ecoenv.2021.112136.

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46

Naffaa, Vanessa, Olivier Laprévote, and Anne-Laure Schang. "Effects of endocrine disrupting chemicals on myelin development and diseases." NeuroToxicology 83 (March 2021): 51–68. http://dx.doi.org/10.1016/j.neuro.2020.12.009.

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47

Oğuz, Ahmet R., and Ertuğrul Kankaya. "Determination of Selected Endocrine Disrupting Chemicals in Lake Van, Turkey." Bulletin of Environmental Contamination and Toxicology 91, no. 3 (2013): 283–86. http://dx.doi.org/10.1007/s00128-013-1036-1.

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48

Nasu, M., M. Goto, H. Kato, Y. Oshima, and H. Tanaka. "Study on endocrine disrupting chemicals in wastewater treatment plants." Water Science and Technology 43, no. 2 (2001): 101–8. http://dx.doi.org/10.2166/wst.2001.0078.

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From July 1998 to March 1999, a study was made of a total of 27 treatment plants for the principal purpose of understanding the actual condition of endocrine disrupting chemicals (EDCs) in sewage, and the behavior of EDCs in wastewater treatment plants. The results showed actual levels of influent and effluent concentrations of EDCs in sewage. Substances detected above the minimum limit of determination were 15 for wastewater influent and 6 for effluent. Similarly, nonyl phenol ethoxylate and 17β-estradiol, which are highlighted as pertinent substances, were detected. It was confirmed that the
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49

Jacobs, M. N. "In silico tools to aid risk assessment of endocrine disrupting chemicals." Toxicology 205, no. 1-2 (2004): 43–53. http://dx.doi.org/10.1016/j.tox.2004.06.036.

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50

De Coster, Sam, and Nicolas van Larebeke. "Endocrine-Disrupting Chemicals: Associated Disorders and Mechanisms of Action." Journal of Environmental and Public Health 2012 (2012): 1–52. http://dx.doi.org/10.1155/2012/713696.

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The incidence and/or prevalence of health problems associated with endocrine-disruption have increased. Many chemicals have endocrine-disrupting properties, including bisphenol A, some organochlorines, polybrominated flame retardants, perfluorinated substances, alkylphenols, phthalates, pesticides, polycyclic aromatic hydrocarbons, alkylphenols, solvents, and some household products including some cleaning products, air fresheners, hair dyes, cosmetics, and sunscreens. Even some metals were shown to have endocrine-disrupting properties. Many observations suggesting that endocrine disruptors do
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