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Journal articles on the topic 'Endometrial malignancy'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Al-Rayes, Sarah, Mariam Mohamed, Eva Suarthana, Hormoz Nassiri Kigloo, Jason Raina, and Togas Tulandi. "Risks of Malignancy among 11,204 Patients with Endometrial Polyp: A Systematic Review and Meta-analysis." Gynecology and Minimally Invasive Therapy 14, no. 1 (2025): 40–50. https://doi.org/10.4103/gmit.gmit-d-24-00056.

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Abstract Objectives: To evaluate factors associated with malignancy in patients with endometrial polyps. Materials and Methods: We conducted electronic database research on PubMed, MEDLINE, EMBASE, COCHRANE, and Google Scholar from inception for all studies on endometrial polyp. After removing duplicates, and title and abstract screening, we had a total of 121 articles and 151 others from screening the reference list. Inclusion criteria included peri and postmenopausal women > 45 years diagnosed histopathologically with endometrial polyp(s). We excluded women with a history of endometrial c

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Joshi, Narendra, Kalpesh Patel, Bhawani Shankar Sharma, Neeraj Choudhary, and Balveer Jakhar. "Prospective study of role of transvaginal sonography in postmenopausal bleeding and its histopathological correlation: a prospective study from a tertiary care hospital of Rajasthan." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 14, no. 4 (2025): 1235–43. https://doi.org/10.18203/2320-1770.ijrcog20250868.

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Postmenopausal bleeding is vaginal bleeding that occurring after one years of menopause. When periods have stopped for more than one years in women who are generally over than 45 years old and it is common condition in postmenopausal women, it can be the presenting symptom of endometrial cancer. Aim of study is to assess endometrial thickness by vaginal sonography and correlate it with the cytological pattern evaluated by endometrial sampling and histopathological typing of the endometrium. Methods: This is a prospective observational study conducted in department of obstetrics and gynaecology

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3

KÖSE, Mesut, Ayhan VURMAZ, and Yasemin ÇELİK. "BENİGN, PRE-MALİGN VE MALİGN ENDOMETRİYAL LEZYONLARDA PROLİDAZ AKTİVİTESİ VE OKSİDATİF STRES." Kocatepe Tıp Dergisi 24, no. 2 (2023): 195–200. http://dx.doi.org/10.18229/kocatepetip.1105749.

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OBJECTIVE: The present study aims to investigate the prolidase activity, total oxidant status (TOS) and total anti-oxidant status (TAS) in women who have been diagnosed with benign, pre-malignant and malignant endometrial pathologies. MATERIAL AND METHODS: Ninety women who underwent endometrial biopsy due to abnormal uterine bleeding were divided into three groups according to their histopathological findings: Benign endometrial pathology (n=65), endometrial hyperplasia (n=12) and endometrial cancer (n=13). These groups were compared with respect to oxidative stress markers and prolidase activ

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Chauhan, Sapna, and Krishnapriya Radhakrishnan. "Clinical profile of endometrial histopathological patterns in Abnormal Uterine Bleeding." Nepal Journal of Obstetrics and Gynaecology 15, no. 1 (2020): 50–54. http://dx.doi.org/10.3126/njog.v15i1.29341.

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Aims: To study the association of clinical profile of patients with Abnormal Uterine Bleeding with the different endometrial histopathological patterns Methods: A retrospective cross-sectional study was done in the department of Obstetrics and Gynaecology at a hospital in Karnataka, India from January 2017 to January 2019. Medical records were reviewed for all the cases of abnormal uterine bleeding who underwent endometrial biopsy. Results: There were 148 records of endometrial biopsies; >55% were in 41-50 years age group; 28% had postmenopausal bleeding; and 28% presented with

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Dr., Sneha Debbarma. "Recognizing Histological Patterns in the Endometrial Scrape Cytology of Hysterectomy Specimens." International Journal of Medical and Pharmaceutical Research 4, no. 2 (2023): 604–10. https://doi.org/10.5281/zenodo.7899798.

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<strong>Background</strong>: There is an absence of standardized diagnostic criteria for endometrial cytology. <strong>Aims</strong>: This study aims at recognizing various patterns seen in endometrial scrape cytology from hysterectomy specimens against histopathological features. The dependability of these patterns for accurate cytological diagnosis of endometrial pathology was assessed. <strong>Materials and methods</strong>: 106 uteri in two separate batches of 50 and 56 received consecutively in surgical pathology laboratory were grossed and their features documented. Each endometrium was

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Nguyen, Hoa Hong, Loan Ha, Nguyen Ngoc Tran, and Thien Minh Trinh. "The risk of endometrial (pre)malignancy in women having postmenopausal uterine bleeding at Tu Du Hospital." MedPharmRes 5, no. 3 (2021): 21–26. http://dx.doi.org/10.32895/ump.mpr.5.3.4.

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Introduction: Endometrial cancer and endometrial atypical hyperplasia, futher referred to as endometrial (pre)malignancy in approximately 8.3-17.6% of cases depending on different studies. The incidence of abnormal endometrium increases during the postmenopausal period, especially endometrial (pre)malignancy. There are limited data regarding endometrial (pre)malignant disorders in patients with postmenopausal uterine bleeding. Purpose: The aim of this study is to investigate the risk of endometrial cancer and atypical hyperplasia in the women who had postmenopausal uterine bleeding (PUB) and a

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Iqbal, A., S. K. S. Murrium, M. Yaseen, K. Shakeel, and M. Z. Iqbal. "Ultrasound Measurement of Endometrial Thickness for Detecting Endometrial Malignancy." Pakistan Journal of Medical and Health Sciences 15, no. 6 (2021): 1136–38. http://dx.doi.org/10.53350/pjmhs211561136.

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Background: Post-menopausal Bleeding is extremely doubtful of existence a mark intended for incidence of EC as well as around 5% to 12% of post-menopausal bleeding consequences commencing endometrial cancer. EC is greatest communal Gynecologic Malignancy into established countries. Thin endometrium (≤4 mm) devours precise high NPV (99%). Thickened Endometrium has been considered by way of sign intended for an offensive assessment. Aim: To determine the ET measurement for detecting endometrial malignancy with uterine bleeding in post-menopausal females. Methods: The search was led according to

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8

Shrestha, Pravin, Smita Shrestha, and Vibha Mahato. "Endometrial study by Ultrasonography and its correlation with Histopathology in Abnormal uterine bleeding." Asian Journal of Medical Sciences 9, no. 2 (2018): 31–35. http://dx.doi.org/10.3126/ajms.v9i2.19171.

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Background: Abnormal Uterine Bleeding is defined as any deviation from a normal menstrual pattern. It is one of the common presentation in extremes of ages. However endometrial hyperplasia and carcinoma are commoner in perimenopausal and postmenopausal women warranting investigations like ultrasonography and endometrial biopsy.Aims and Objective: The aim of the study was to note the endometrial thickness by transabdominal ultrasonography and observe the histopathological pattern in women presenting with abnormal Uterine Bleeding.Material and Methods: Premenopausal women more than 45 years of a

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Gündüz, Reyhan, Elif Ağaçayak, Gülcan Okutucu, Ulaş Alabalik, and Mehmet Sıddık Evsen. "Evaluation of definitive histopathological results of patients diagnosed with endometrial polyps: a tertiary care center experience." African Health Sciences 22, no. 1 (2022): 125–32. http://dx.doi.org/10.4314/ahs.v22i1.16.

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Objectives: To determine the premalignancy and malignancy prevalence in patients diagnosed with endometrial polyps and to investigate factors affecting premalignancy and malignancy. Methods: In our retrospective study, patients who were diagnosed with endometrial polyp with endometrial samples and who underwent polypectomy by hysteroscopy or hysterectomy within one year were included. Results: Premalignant / malignant histopathological results were detected in 7 (2.8%) patients. There were no statistically significant differences in histopathological results and endometrial samplin

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Pfleiderer, Albrecht. "ENDOMETRIAL MALIGNANCY." Current Opinion in Obstetrics and Gynecology 3, no. 1 (1991): 91–99. http://dx.doi.org/10.1097/00001703-199102000-00014.

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M., Priya, C. R. Anuradha, and Vijayashree Raghavan. "A retrospective study on endometrial patterns in abnormal uterine bleeding." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 11, no. 8 (2022): 2194. http://dx.doi.org/10.18203/2320-1770.ijrcog20221936.

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Background: To determine the type of endometrial patterns of the different age categories of women who presented as a case of abnormal uterine bleeding.Methods: This is a retrospective study conducted on 105 patients who presented with abnormal uterine bleeding who underwent fractional curettage in our hospital. The data on their age, presenting complaints, and comorbidities of all the women were collected. The patterns of endometrial changes were studied and classified.Results: The most common histopathological findings were anovulatory shedding (34.3%) and irregular shedding (18.1%). The oth

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Hemalatha S V, G. Thenmozhi, and M. S. Manickadevi. "Clinicopathological evaluation of patients with postmenopausal bleeding in a tertiary care center." Indian Journal of Obstetrics and Gynecology Research 10, no. 1 (2023): 59–62. http://dx.doi.org/10.18231/j.ijogr.2023.012.

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Postmenopausal bleeding (PMB) is frequent finding in 5-10% of women in gynaecology clinic. About 10% of these patients have primary or secondary malignancy. PMB requires complete assessment to ensure the absence of malignancy and to identify and treat high risk patients such as those with endometrial hyperplasia.The aim of this study is to investigate the clinical significance and endometrial pathology in patients with PMB.A retrospective study on postmenopausal women visiting a tertiary care center between 2016 January to 2017 December was taken up for study. About 80 patients with PMB were s

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Tofiloska, Valentina, Vesna Velik-Stefanovska, and Goran Dimitrov. "The Connection between the Endometrial Thickness and the Risk of Endometrial Malignancy in Postmenopausal Women." Open Access Macedonian Journal of Medical Sciences 7, no. 14 (2019): 2263–66. http://dx.doi.org/10.3889/oamjms.2019.639.

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BACKGROUND: Postmenopausis is a period that starts one year after the last menstruation. Late menopause, after 70 years, is called senile. AIM: To examine the correlation between endometrial thickness and the risk of endometrial malignancy in postmenopausal. MATERIAL AND METHODS: Prospective clinical study involving 120 postmenopausal patients treated at the University Clinic for Gynecology and Obstetrics – Skopje, divided into two groups: control and examination. The control group included 40 postmenopausal patients, hospitalised and operated due to urogenital pathology. The exami

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14

Van Doorn, H. C., B. C. Opmeer, M. Jitze Duk, R. F. M. P. Kruitwagen, F. P. H. L. J. Dijkhuizen, and B. W. Mol. "The relation between age, time since menopause, and endometrial cancer in women with postmenopausal bleeding." International Journal of Gynecologic Cancer 17, no. 5 (2007): 1118–23. http://dx.doi.org/10.1111/j.1525-1438.2007.00925.x.

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The objective is to assess among women with postmenopausal bleeding the relationship of age and time since menopause on one hand and the presence of endometrial cancer and atypical hyperplasia on the other hand. In a multicenter prospective cohort study, 614 women presenting with postmenopausal bleeding were included. Women underwent transvaginal sonography and, in cases where the endometrial thickness was >4 mm, endometrial sampling. Splines were used to assess the association between each of the continuous variables and (pre)malignancy of the endometrium. Subsequently, univariate and mult

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De Leon, Maria B., Wu Howard, and Giuseppe Del Priore. "Novel approach to outpatient endometrial biopsy to detect endometrial cancer." Journal of Clinical Oncology 31, no. 15_suppl (2013): e16522-e16522. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.e16522.

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e16522 Background: Currently there is no consensus on the best device and technique for obtaining endometrial biopsies to rule out cancer. Outpatient methods available include aspiration devices (Pipelle) and disruption devices (Tao brush). This study evaluated a new device which combines Global endometrial Disruption using a brush with a built in suction Process (GDP-Tao). Methods: After IRB approval, endometrial specimens were collected using the GDP-Tao from fresh uteri after completion of hysterectomies. Endometrial pathology results from the new device were compared to the final hysterect

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van Niekerk, Catharina C., Johan Bulten, G. Peter Vooijs, and André L. M. Verbeek. "The Association between Primary Endometrioid Carcinoma of the Ovary and Synchronous Malignancy of the Endometrium." Obstetrics and Gynecology International 2010 (2010): 1–5. http://dx.doi.org/10.1155/2010/465162.

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Objective. Ovarian and endometrial cancers coincide rather frequently in the same patient. Few data are available on the involvement of the specific morphological subtypes. To identify histological pathways in the synchronous occurrence, a population-based study was performed in The Netherlands.Methods. Using the national pathology database (PALGA) information of ovarian cancers and of earlier or later cancer in the endometrium was obtained. 5366 Patients were identified with primary malignant epithelial or borderline malignancy.Results. In 157 cases (2.9%) a new primary malignancy in the endo

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V., V. Artyomenko, V. Chumak Z., and V. Shapoval M. "THE RETROSPECTIVE ANALYSIS RESULTS OF THE ENDOMETRIAL TISSUE PATHOLOGICAL CONDITIONS DEVELOPMENT." REPRODUCTIVE ENDOCRINOLOGY, no. 55 (November 30, 2020): 48–52. https://doi.org/10.18370/2309-4117.2020.55.48-52.

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Hyperplastic processes of endometrium are one of the most common pathologies of the uterus mucosa, an interest in its study is due to an increase in the frequency of occurrence, the ability to both self-healing and malignancy. <strong>Purpose of the study:</strong> to investigate the detection rate of endometrial proliferative changes  depending on the age of woman. <strong>Materials and methods.</strong> A retrospective medical documentation analysis of the Department of Pathology was conducted. 2196 pathologic findings of endometrial tissue samples were investigated. 1404 spec

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Mishra, Shilpa, and Rakesh Patkar. "Extensive morular metaplasia in an endometrial polyp – A rare occurrence - creating a diagnostic dilemma." IP Archives of Cytology and Histopathology Research 8, no. 2 (2023): 126–29. http://dx.doi.org/10.18231/j.achr.2023.029.

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Morular metaplasia is an unusual type of metaplastic change, often observed in numerous endometrial lesions. It has been considered a variant of squamous metaplasia and has a mulberry-like appearance. Morular metaplasia lacks the characteristic histopathological features of conventional squamous differentiation and hence their relationship with each other has not been clearly defined. These lesions are usually seen along with pre-malignant and malignant glandular lesions of endometrium. Their presence in normal endometrium or benign endometrial polyps is rare, however it can cause a diagnostic

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Iqbal, Alia, Syeda Khadija-Tul-Sughra Murrium, Maria Yaseen, Kiran Shakeel, and Muhammad Zafar Iqbal. "Ultrasound Measurement of Endometrial Thickness for Detecting Endometrial Malignancy with Uterine Bleeding in Postmenopausal Women- A Systematic Review." Pakistan Journal of Medical and Health Sciences 15, no. 7 (2021): 1461–63. http://dx.doi.org/10.53350/pjmhs211571461.

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Background: Post-menopausal Bleeding is extremely doubtful of existence a mark intended for incidence of EC as well as around 5% to 12% of post-menopausal bleeding consequences commencing endometrial cancer. EC is greatest communal Gynecologic Malignancy into established countries. Thin endometrium (≤4 mm) devours precise high NPV (99%). Thickened Endometrium has been considered by way of sign intended for an offensive assessment. Aim: To determine the ET measurement for detecting endometrial malignancy with uterine bleeding in post-menopausal females. Methods: The search was led according to

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Lata, Gagan, Susmita Sharma, Sukhbir Pal Kaur, and Sandhya Panjeta Gulia. "Histo-pathological pattern of endometrial biopsy in females with abnormal uterine bleeding: a retrospective study in tertiary care hospital of Haryana." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 9, no. 10 (2020): 4068. http://dx.doi.org/10.18203/2320-1770.ijrcog20204289.

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Background: This study aimed to know the various histo-pathological patterns of endometrial biopsy and their incidence in patients of AUB.Methods: Patients in the age group between 21-75 years who had presented with AUB and underwent endometrial biopsy from 1st January 2017 to 31st December 2019 were included. The endometrial biopsy specimens which were already taken from patients with AUB were scrutinized for histopathological pattern. Various patterns of histo-pathology of endometrial biopsy were noted and studied.Results: Most common age group which was affected was between 36-40 years. The

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International, Journal of Medical Science and Innovative Research (IJMSIR). "Diagnostic Efficacy of Endometrial Aspiration Cytology with Histopathological Correlation." International Journal of Medical Science and Innovative Research (IJMSIR) 9, no. 6 (2024): 08–14. https://doi.org/10.5281/zenodo.15449508.

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<strong>Abstract</strong> <strong>Introduction</strong>: Endometrial cytopathology is a powerful tool for the detection of a wide variety of benign atypias, inflammatory changes, and infectious organisms. It is also helpful for the cyto-hormonal evaluation of patients and the detection of endometrial malignancies. <strong>Aims</strong>: To assess the diagnostic accuracy of endometrial aspiration technique and to compare the cyto-morphology of aspirated smears with histopathology<sup> </sup> Materials and Methods:<em> </em>Endometrial aspiration was performed using Karman’s cannula in 100

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Amudhavalli, Singaram, Krishnamurthy Prathipa, Krishnaswamy Rama, and Infant Arockiasamy Babiya. "Incidence and Clinicopathological Assessment of Endometrial Carcinoma and their Precursor Lesions in a Tertiary Care Hospital." International Journal of Pharmaceutical and Clinical Research 15, no. 8 (2023): 607–14. https://doi.org/10.5281/zenodo.11491484.

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<strong>Introduction:</strong> Endometrial cancer is the commonest gynaecologic malignancy in developed countries. Hyperplasia of endometrium with atypia carries increased risk of 29% of transforming to malignancy. There is morphological overlap between atypical hyperplasia and well differentiated carcinoma making their histological differentiation, a diagnostic problem especially in curetting specimens. This distinction has clinical significance and this study is aimed to observe the incidence, distribution and clinicopathological profile of endometrial hyperplasias and endometrial carci

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Jyoti, Kumari, Kumari Suman, and Saurabh Suvidha. "Evaluation of Clinical Significance and Endometrial Pathology in Patients with Postmenopausal Bleeding in a Tertiary Care Center." International Journal of Pharmaceutical and Clinical Research 16, no. 10 (2024): 665–69. https://doi.org/10.5281/zenodo.14038220.

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<strong>Background</strong>: Postmenopausal bleeding is frequent in gynecology and occurs approximately in 5% to 10% of postmenopausal women. But most of the causes of post-menopausal bleeding are benign and treated conservatively. Women with postmenopausal bleeding have a primary or secondary malignancy of about 10%. So before starting treatment malignancy must be excluded. Common malignancies among them are endometrial or cervical carcinoma and rarely, ovarian cancer. The incidence of malignancy in the postmenopausal period remains sufficiently high, so it requires immediate investigations f

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R., Sajeetha Kumari, and Anuradha M. "Endometrial patterns in abnormal uterine bleeding: a retrospective study." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 6, no. 11 (2017): 4966. http://dx.doi.org/10.18203/2320-1770.ijrcog20175009.

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Background: Abnormal uterine bleeding (AUB) is a common reason for women of all ages to consult their gynecologist and is one of the most common debilitating menstrual problems ending up in hysterectomy in developing countries. The aim of the present study was to determine the clinical spectrum and frequency of pathologies in endometrial biopsy of patients with AUB in our population. We also tried to observe the incidence of various pathologies in different age groups presenting with abnormal uterine bleeding.Methods: The study was conducted in SRM Medical College Hospital and Research Centre,

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Junnare, K. K., G. J. Desai, and G. S. Shekhawat. "Hysteroscopy: an effective tool in post-menopausal bleeding." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 8, no. 1 (2018): 159. http://dx.doi.org/10.18203/2320-1770.ijrcog20185415.

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Background: Postmenopausal bleeding is a condition where endometrial carcinoma is to be ruled out. Traditionally, D and C is the preferred method for diagnosis in such condition. Other diagnostic modalities like trans vaginal ultrasonography (TVS) and hysteroscopy are being used for diagnosis in the cases of PMB. The objective of this study is to evaluate the efficacy and accuracy of TVS and hysteroscopy in women with postmenopausal bleeding (PMB).Methods: One hundred postmenopausal women with vaginal bleeding underwent TVS and hysteroscopy. Endometrial tissue was obtained by curettage and sen

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Antovska, Vesna S., Iskra Krstevska, Milka Trajanova, et al. "Endometrioid Adenocarcinoma Arising in Adenomyoma in a Woman with a Genital Prolapse - Case Report." Open Access Macedonian Journal of Medical Sciences 6, no. 6 (2018): 1091–94. http://dx.doi.org/10.3889/oamjms.2018.239.

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BACKGROUND: Endometrial cancer is the third-ranked genital malignancy in women and includes 3% of cancer deaths. There is a 2.8% chance of a woman developing endometrial cancer during her lifetime. Low-grade endometrioid adenocarcinomas are often seen along with endometrial hyperplasia, but high-grade endometrioid adenocarcinomas have more solid sheets of less-differentiated tumour cells, which are no longer organised into glands, often associated with surrounded atrophic endometrium.CASE REPORT: We present an unusual case of endometrial adenocarcinoma arising in adenomyoma in 74-year old woma

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Kumari, Khusboo, Manoj Kumar Paswan, Meghraj Kundan, and Shivlok N. Ambedkar. "A prospective study of endometrial histopathology in post-menopausal women in Jharkhand." Journal of Family Medicine and Primary Care 13, no. 5 (2024): 1696–700. http://dx.doi.org/10.4103/jfmpc.jfmpc_1331_23.

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ABSTRACT Introduction: Postmenopausal bleeding (PMB) refers to any uterine bleeding in a menopausal women. In the early menopausal years, endometrial hyperplasia, polyps and submucosal fibroids are common etiologies of post menopausal bleeding. The most common cause of postmenopausal bleeding is endometrial atrophy, comprises of 60-80%, while endometrial hyperplasia and endometrial cancer contribute to only 11% of Post menopausal bleeding. The aim of study is to analyses histomorphological pattern of endometrium in patients presenting with post-menopausal bleeding in Jharkhand. Materials and M

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Choudhary, Anjali, Shikha Agarwal, Swati Kohli, Shweta Mishra, and Parul Singh. "Endometrial histopathology patterns in women with abnormal uterine bleeding." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 11, no. 2 (2022): 477. http://dx.doi.org/10.18203/2320-1770.ijrcog20220173.

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Background: Abnormal uterine bleeding is the most common gynaecological condition for which many women seek medical opinion. Evaluation of these women requires careful investigation into the cause and nature of bleeding with a main focus to exclude organic pathology, especially genital malignancies. Endometrial biopsy is one such intervention which is of immense value in categorizing the conditions. Aims and objectives of current study were to analyse endometrial histology patterns in women with AUB.Methods: This was a retrospective study conducted on women with AUB who presented in the gynae

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Asaithambi, Shubha Supriya, Shruthi Swamy, Shashidhar V. Karpurmath, Manjunath Nandennavar, and Veerendra Angadi. "Synchronous ovarian granulosa cell tumor and carcinoma endometrium due to excess estrogen secretion: a rare presentation." International Journal of Research in Medical Sciences 13, no. 1 (2024): 445–49. https://doi.org/10.18203/2320-6012.ijrms20244154.

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Granulosa cell tumor (GCT) is a low malignant potential ovarian tumor accounting for 70% of all sex cord stromal tumor. It is an estrogen secreting tumor, hence diagnosed in early stages, associated with 20-30% concomitant lesion in endometrium including 5% of invasive adenocarcinoma. Through this case report we present the synchronous occurrence of ovarian and endometrial malignancy of a 52-year-old female, P3L2A0 who presented with irregular menstrual bleeding since 2 months along with literature review. Imaging showed endometrial lesion with synchronous left ovarian lesion with a normal CA-

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Ubeja, Astha, and Amreen Singh. "Clinicopathological evaluation of postmenopausal bleeding in rural hospital set up." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 6, no. 8 (2017): 3556. http://dx.doi.org/10.18203/2320-1770.ijrcog20173483.

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Background: Postmenopausal bleeding should be completely assessed to ensure the absence of malignancy and to identify and treat high risk patients such as those with endometrial hyperplasia. The aim of present study was to investigate the clinical significance and endometrial pathology in patients with postmenopausal bleeding.Methods: A cross sectional study was carried on 100 patients with postmenopausal bleeding visiting Acharya Vinobha Bhave rural hospital, Sawangi between August 2009-December 2011. Patients were evaluated according to pelvic ultrasound, fractional curettage and endometrial

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Al-Zubaidi, Lina, Salam Joori, and Hiba Abdulwahid. "The value of dynamic contrast-enhanced MRI and diffusion-weighted sequence in the evaluation of endometrial lesions." Scripta Medica 55, no. 1 (2024): 13–22. http://dx.doi.org/10.5937/scriptamed55-47768.

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Background/Aim: Endometrial abnormalities represent a diagnostic challenge due to overlapping imaging features with normal endometrium. Aim of this study was to assess accuracy of dynamic contrast-enhanced and diffusion-weighted magnetic resonance imaging (MRI) in evaluation of endometrial lesions in comparison with T2 and to assess local staging validity and degree of myometrial invasion in malignancy. Methods: Forty patients with abnormal vaginal bleeding or sonographic thickened endometrial were recruited. MRI examination of pelvis was per-formed using 1.5 T scanner with a pelvic array coil

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Agrawal, Priti, Rishi Agrawal, Jaswant Jain, and Anandi Lobo. "Postmenopausal endometrial carcinoma presenting as urinary incontinence: a case report." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 10, no. 6 (2021): 2544. http://dx.doi.org/10.18203/2320-1770.ijrcog20212215.

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Endometrial carcinoma (EC) most commonly presents with postmenopausal bleeding (PMB) or blood tinged vaginal discharge. Watery vaginal discharge is usually reported in fallopian tube malignancy. We reported a case of EC where she had profuse watery discharge from private part mimicking urine and so patient visited urologist for urinary incontinence and was later diagnosed as endometroid adenocarcinoma. A 73 year old female presented with history of passing urine involuntarily for last 3 months. Endometrial biopsy revealed endometrial endometroid adenocarcinoma-FIGO grade-2. FDG PET-CT scan rev

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Savchenko, P. V., I. S. Shponka, P. O. Hrytsenko, and O. A. Savchenko. "Proliferation activity and hormonal status of atypical hyperplasia and endometrioid adenocarcinoma of the endometrium." Pathologia 21, no. 1 (2024): 51–56. http://dx.doi.org/10.14739/2310-1237.2024.1.299170.

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Atypical hyperplasia of the endometrium is a precancerous condition for endometrioid adenocarcinoma of the endometrium, which is the largest group among malignant neoplasms of the uterine body, according to the Cancer Registry, the mortality rate from which took the 3rd place in 2021. The absence of specific clinical manifestations complicates diagnostics at the early stages of the process, which necessitates the study of histological and immunohistochemical criteria to verify the diagnosis. The aim of the study. To improve the differential diagnostic morphological and immunohistochemical crit

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Salguero-Sánchez, Jefferson, and Leonardo González-García. "Riesgo de malignización de pólipos endometriales." Revista de Obstetricia y Ginecología de Venezuela 82, no. 01 (2022): 98–102. http://dx.doi.org/10.51288/00820112.

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Endometrial polyps are common lesions and their prevalence in the general population is relatively low; however, they can be associated with abnormal uterine bleeding, increased risk of endometrial cancer and, in some cases, infertility. These conditions can be considered as a malignant lesion depending on their characteristics. The risk of malignancy of an endometrial polyp varies between 0.8% to 8%. The malignancy that these represent cannot be observed in isolation but rather together with the other factors that increase the risk of endometrial cancer. The diagnosis is principally realized

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Khatik, Neha, Arti Tiwari, and Kalpana Yadav. "Histopathological evaluation of endometrium and its clinical correlation in patients of abnormal uterine bleeding." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 9, no. 10 (2020): 4169. http://dx.doi.org/10.18203/2320-1770.ijrcog20204308.

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Background: Abnormal uterine bleeding (AUB) is a very common, challenging gynaecological problem in all age group women. Neoplastic lesions are responsible for very less number of cases but they should be diagnosed early. Endometrial biopsy is necessary for histopathological diagnosis of endometrial lesions and to rule out any malignancy. In present study, we evaluated histopathological pattern of endometrium and different clinical parameters in AUB patients.Methods: A retrospective observational study done in Obstetrics and Gynecology department of SSMC Rewa, Madhya Pradesh in 2 year from 1st

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Raman, Jayasree, Prakash Pushpangadan, Febby K. Philip, and Shobha S. Pillai. "Histopathological evaluation of endometrial patterns in workup of abnormal uterine bleeding." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 11, no. 9 (2022): 2385. http://dx.doi.org/10.18203/2320-1770.ijrcog20222298.

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Background: Abnormal uterine bleeding (AUB) is defined as bleeding pattern that differs in frequency, duration and amount from the normal cyclical flow. Endometrium in AUB vary depending on etiology and age. The present study attempts to categorize the histopathology of endometrium in abnormal uterine bleeding in women of various age groups.Methods: A hospital based prospective study was carried out in 220 cases of abnormal uterine bleeding. Paraffin processed endometrial biopsies analyzed correlating the clinico-radiological data. Endometrial samples of infertility and pregnancy related bleed

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Rusda, Muhammad, Andri Sipahutar, and Andrina Yunita Murni Rambe. "Application of International Endometrial Tumor Analysis in Abnormal Uterine Bleeding: A Case Report." Open Access Macedonian Journal of Medical Sciences 10, T7 (2022): 7–11. http://dx.doi.org/10.3889/oamjms.2022.9236.

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BACKGROUND: Abnormal uterine bleeding (AUB) is one of the clinical symptoms found in malignant conditions where the incidence of newly diagnosed cancers reached 100,000 cases in Europe in 2012 with an incidence of around 14.7/100,000 women. The International Endometrial Tumor Analysis (IETA) group, formed in Chicago in 2008, published a consensus stating how to examine and measure the endometrium. CASE REPORT: Mrs. M, 49 years old, came to Gynecology Clinic of USU Hospital on February 22, 2021, at 13.00 WIB with the complaints of prolonged menstruation for 2 months with a volume of >10 time

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Doğan-Ekici, A. Işın, Alp Usubütün, Türkan Küçükali, and Ali Ayhan. "Xanthogranulomatous Endometritis: A Challenging Imitator of Endometrial Carcinoma." Infectious Diseases in Obstetrics and Gynecology 2007 (2007): 1–3. http://dx.doi.org/10.1155/2007/34763.

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Xanthogranulomatous inflammation is a distinguished histopathological entity affecting several organs, predominantly the kidney and gallbladder. So far, only a small number of cases of xanthogranulomatous inflammation occurring in female genital tract have been described, most frequently affecting the endometrium and histologically characterized by replacement of endometrium by xanthogranulomatous inflammation composed of abundant foamy histiocytes, siderophages, giant cells, fibrosis, calcification and accompanying polymorphonuclear leucocytes, plasma cells and lymphocytes of polyclonal origi

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Jimo, Kanili, Nounechutuo Miachieo, Bendangtoshi Jamir, Rebeki Momin, and Nito Yepthomi. "Endometrial tuberculosis mimicking endometrial malignancy - histopathology key to management¬ - a case report." New Indian Journal of OBGYN 10, no. 1 (2023): 236–38. http://dx.doi.org/10.21276/obgyn.2023.10.1.44.

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Al Fattah, Adly N., Tricia D. Anggraeni, Bella Aprilia, and Muhammad Ikhsan. "Do we need more than ultrasound endometrial thickness to predict malignancy?" International Journal of Reproduction, Contraception, Obstetrics and Gynecology 7, no. 3 (2018): 766. http://dx.doi.org/10.18203/2320-1770.ijrcog20180852.

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Endometrial thickness (ET) ultrasound measurement has high diagnostic performance for detection of endometrial cancer in symptomatic postmenopausal women. Identified clinical risk factors, Doppler or 3D ultrasound parameters to predict endometrial malignancy had been proposed in several studies. We compared the accuracy of ultrasound endometrial thickness with scoring system/index involving both of clinical and ultrasound parameters to predict endometrial malignancy. Eight eligible diagnostic studies were appraised to assess the accuracy of ultrasound ET and/or ultrasound-based index to predic

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Fãtu, Ion Constantin, Constantin Fãtu, and Mihaela Puisoru. "Morphometric analysis of nuclear-cytoplasm features in endometrial pre-cancerous and malignant lesions." Electronic Journal of Pathology and Histology 7, no. 2 (2001): 04. https://doi.org/10.3233/eph-2001-7_2_04.

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Endometrial tissue alterations consist of a wide scale of histopathological lesions ranging between benign hyperplasia and endometrial carcinoma. Specific forms of endometrial hyperplasia are well known pre-malignant lesions. A quantitative histopathological analysis has been performed in order to provide an objective support for differential diagnosis in these cases. An increase of the nuclear area and various cytoplasm features was seen in relation with enhanced grades of endometrial malignancy. Thus, quantitative and stereological methods provide an accurate tool to support the diagnosis an

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Ferdous, Fatheha, Ferdousi Begum, Nahid Sultana, and Tahrina Akter. "Histopathological Study of Endometrium in Postmenopausal Bleeding." Bangladesh Journal of Obstetrics & Gynaecology 35, no. 2 (2022): 112–16. http://dx.doi.org/10.3329/bjog.v35i2.58796.

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Background & objectives: Postmenopausal bleeding is frequent in gynecology and occurs approximately in 5% to 10 % of postmenopausal women. About 10% women with postmenopausal bleeding have a primary or secondary malignancy. Common malignancies among them are endometrial or cervical carcinoma and rarely, ovarian cancer. The incidence of malignancy in postmenopausal period remains sufficiently high, so it requires immediate investigations for early diagnosis, prompt treatment and vigilant follow up. The objective of the present study is to evaluate the causes of postmenopausal bleeding based

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Charisma, Rebecca Thomas, and R. Chithra. "The Diagnostic Accuracy of DEERS (Disease of Endometrium- Evaluation and Risk Scoring System) For Prognostication of (AUB) Abnormal Uterine Bleeding." International Journal of Pharmaceutical and Clinical Research 15, no. 10 (2023): 459–65. https://doi.org/10.5281/zenodo.11257520.

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<strong>Background: </strong>One of the most frequent presenting problems among women in the reproductive and perimenopausal age range is abnormal uterine bleeding (AUB). Endometrial hyperplasia is a possibility in 5–15% of AUB patients. The most reliable method for determining the causes of endometrial diseases is endometrial sampling. Reports from tissue biopsies might be benign, malignant, premalignant, or normal. In order to predict AUB, the DEERS (Disease of Endometrium- Evaluation and Risk Scoring) scoring system was developed. It uses demographic and ultrasonographic variable

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Sarbhai, Vinita, and Ayushi Sinha. "Role of Colour Doppler and Transvaginal Sonography for diagnosis of endometrial pathology in women presenting with Abnormal Uterine Bleeding." International Journal of Current Research and Review 14, no. 08 (2022): 58–63. http://dx.doi.org/10.31782/ijcrr.2022.14810.

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Introduction: Transvaginal Sonography has emerged as important modality in investigating AUB, but it cannot diagnose endometrial pathology in absence of histopathology of endometrium. Addition of Color doppler (CDTU) to TVS can help in diagnosis by evaluation of blood flow through vascular patterns and Uterine artery indices. Objective: To evaluate the role of Trans vaginal Ultrasonography and Colour Doppler (CDTU) in abnormal uterine bleeding and correlating them with histopathological diagnosis. Methods: TVS and Colour Doppler were performed in 70 patients with AUB. TVS included evaluation o

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Wong, Michael, Nikolaos Thanatsis, Federica Nardelli, Tejal Amin, and Davor Jurkovic. "Risk of Pre-Malignancy or Malignancy in Postmenopausal Endometrial Polyps: A CHAID Decision Tree Analysis." Diagnostics 11, no. 6 (2021): 1094. http://dx.doi.org/10.3390/diagnostics11061094.

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Background and aims: Postmenopausal endometrial polyps are commonly managed by surgical resection; however, expectant management may be considered for some women due to the presence of medical co-morbidities, failed hysteroscopies or patient’s preference. This study aimed to identify patient characteristics and ultrasound morphological features of polyps that could aid in the prediction of underlying pre-malignancy or malignancy in postmenopausal polyps. Methods: Women with consecutive postmenopausal polyps diagnosed on ultrasound and removed surgically were recruited between October 2015 to O

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Kathuria, Priyanka. "#331 : Bilateral Endometriomas Masquerading Synchronous Endometrial and Ovarian Cancer (SEOC) in an Infertile Female." Fertility & Reproduction 05, no. 04 (2023): 512–13. http://dx.doi.org/10.1142/s2661318223742753.

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Background and Aims: Endometriomas are diagnosed in clinical practice by imaging (mostly ultrasound) in females presenting with infertility. CA-125 level is an adjuvant investigation which may be indicative of endometriosis. A few research questions that are yet to be answered. Is ultrasound a sufficient modality to diagnose endometrioma? Is there any cut off as far as the measurement of endometrioma is concerned to step up the imaging modality to MRI? Synchronous endometrial and ovarian cancer (SEOC) is a rare phenomenon with an incidence of 1.4 - 3.8%. Mostly in SEOC, the ovarian endometroid

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Baqai, Shehla M., Viqar Ashraf, Rabia Sajjad, and Aqsa Qayyum. "Trends of Different Gynaecological Cancers at Combined Military Hospital Lahore; An Overview of Last Five Years." Pakistan Armed Forces Medical Journal 72, no. 4 (2022): 1152–55. http://dx.doi.org/10.51253/pafmj.v72i4.5940.

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Objective: To observe trends of gynaecological malignancies at Combined Military Hospital Lahore. Study Design: Cross-sectional study. Place and Duration of Study: Combined Military Hospital Lahore Pakistan, from Jan 2015 to Dec 2019. Methodology: Data was retrieved from patient admission and discharge notes and their records at the pathology department. Variables like trends of gynaecological malignancies, mean age, common presenting complaint, and common malignancy with histopathology type were collected. Results: A total of 107 patients were selected from 2015-2019.

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Saleh, Agustria Z. "PREVENTION OF ENDOMETRIAL CANCER." Conferences of Medical Sciences Dies Natalis Faculty of Medicine Universitas Sriwijaya 3, no. 1 (2021): 154–58. http://dx.doi.org/10.32539/confmednatalisunsri.v3i1.85.

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Endometrial carcinoma is a malignancy originating from the epithelial cells lining the uterine cavity. 1,3 Currently, endometrial carcinoma is often found in gynecological malignancies. Endometrial carcinoma is the sixth leading cause of death from malignancy in women. In Indonesia, endometrial cancer ranks third for genital cancer after cervical (cervical) and ovarian cancer. An endometrial biopsy is done to diagnose and evaluate abnormal intrauterine bleeding, t. However, in patients who cannot undergo an endometrial biopsy because of cervical stenosis or symptoms persist despite normal biop

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Repše Fokter, Alenka. "Endometrial cancer in young woman." Acta Medico-Biotechnica 13, no. 2 (2021): 60–64. https://doi.org/10.18690/actabiomed.206.

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Purpose: Endometrial cancer is a common malignant disease for which there is no cost-effective early detection screen. Endometrial cancer primarily affects older women and is usuallydiagnosed after symptoms occur. This malignancy is extremely rare in women younger than 40-years-old, so it is rarely considered, especially in asymptomatic cases. Endometrial cells should be evaluated and reported in cervicovaginal smears, but the sensitivity and positive predictive value of Pap tests for the detection of endometrial carcinoma is low.Case report: This is a case report of a 30-year-old asymptomatic

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Koblížková, Michaela, Petra Bretová, Michal Felsinger, Luboš Minář, Markéta Bednaříková, and Vít Weinberger. "Ultrasound finding of endometrial polyp and factors increasing risk of malignancy." Česká gynekologie 89, no. 1 (2024): 44–51. http://dx.doi.org/10.48095/cccg202444.

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This article presents a comprehensive review of factors that increase the risk of malignancy in ultrasound findings of an endometrial polyp. We collected original studies, reviews, and meta-analyses that dealt with the topic of endometrial polyps and the risk of developing endometrial cancer. Each presumed risk factor was analysed individually. According to searched studies, abnormal uterine bleeding, old age, and body mass index are valid risk factors for developing endometrial cancer in endometrial polyps. Lynch syndrome patients are also in a high-risk group for endometrial cancer. On the o

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