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Journal articles on the topic 'Endometroid Adenocarcinoma'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

International, Journal of Medical Science and Innovative Research (IJMSIR). "A Big Lump in A Bump - Giant Endometroid Ovarian Adenocarcinoma – A Case Report." International Journal of Medical Science and Innovative Research (IJMSIR) 9, no. 4 (2024): 35–38. https://doi.org/10.5281/zenodo.15424243.

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Endometroid carcinoma accounts for 10% of the ovarian cancer and it’s the second most common type of epithelial ovarian cancer. We hereby present a rare case of giant abdominopelvic mass that occurred in a 41 year old multiparous lady with retinitis pigmentosa which was assessed by ultrasound and Computed tomography. She underwent primary cytoreductive surgery with frozen section with bilateral pelvic lymph node dissection with infracolic omentectomy. In histopathology diagnosis of ovarian cancer with endometroid pattern was made. Diagnosis play an important role in detection, staging an

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2

Zivanovic, Aleksandar, Aleksandra Dimitrijevic, Tatjana Kastratovic, Janko Djuric, Vesna Stankovic, and Irena Tanaskovic. "Ovarian endometroid adenocarcinoma in pregnancy." Vojnosanitetski pregled 68, no. 2 (2011): 181–84. http://dx.doi.org/10.2298/vsp1102181z.

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Background. Ovarian cancer is very rare in pregnancy. It is mainly of epithelial origin, low grade and low malignant potential. Case report. We presented a patient in which ultrasound confirmed the presence of clearly limited tumor in the left ovary when she was eight weeks pregnant. The results of 4D Color Doppler showed a central type of tumor vascularisation with resistance index (IR) less than 0.5. The Consultancy Board in Gynecology of the Institute for Oncology and Radiology of Serbia decided to remove the patient's left adnexa and intensively monitor the pregnancy period. The operation

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Catena, U., M. Mirandola, F. M. Capomacchia, F. Fanfani, and G. Scambia. "A new surgical approach for fertility-sparing management of diffuse endometrial G2 endometrioid adenocarcinoma: a step-by-step technique." Facts, Views and Vision in ObGyn 15, no. 1 (2023): 79–81. http://dx.doi.org/10.52054/fvvo.15.1.058.

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Background: 4% of endometrial cancers are diagnosed in young women and 70% are nulliparous. Preserve fertility in these patients is of major interest. It is demonstrated that hysteroscopic resection of focal well-differentiated endometrioid adenocarcinoma, followed by progestins achieve a complete response rate of 95.3%. Recently, fertility-sparing treatment was proposed also in case of moderately differentiated endometrioid tumors, with a relatively high remission rate. Objective: To show a new hysteroscopic approach, in case of fertility-sparing treatment of diffuse endometrial G2 endometrio

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Purandare, Nikhil C., Gillian Ryan, Fathl Ramli, Kara Purcell, Andrew Curtain, and Morgan McCourt. "Endometroid Adenocarcinoma: A Possibility after Hysterectomy." Journal of South Asian Federation of Obstetrics and Gynaecology 2, no. 3 (2010): 230–32. http://dx.doi.org/10.5005/jp-journals-10006-1108.

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5

Beresford-Cleary, N., S. Mehdi, and B. Magowan. "Femoral metastases from ovarian serous/endometroid adenocarcinoma." Journal of Surgical Case Reports 2012, no. 7 (2012): 9. http://dx.doi.org/10.1093/jscr/2012.7.9.

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6

Mahantshetty, Umesh, Aditi Aggarwal, Balasubramanium Ganesh, et al. "Clinical Outcome of Early-Stage Endometroid Adenocarcinoma." International Journal of Gynecological Cancer 23, no. 8 (2013): 1446–52. http://dx.doi.org/10.1097/igc.0b013e3182a2ff46.

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Kazmi, Alina, Noorin Zaidi, and Sumaiya Irfan. "Mixed cell adenocarcinoma of uterus: A case report." Indian Journal of Pathology and Oncology 10, no. 3 (2023): 288–90. http://dx.doi.org/10.18231/j.ijpo.2023.062.

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Here we present a case of a 40-year old obese female admitted with the complaint of lower abdominal pain, pain during sexual intercourse and irregular menstruation. The transabdominal ultrasonography showed increased endometrial thickness. Histopathological examination showed (clear cell adenocarcinoma, endometroid carcinoma with squamous differentiation) mixed cell adenocarcinoma which is a very rare case.

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Hocker, Nathaniel, Maria Story, Alysa Lerud, and Sarat Kuppachi. "Severe hypercalcaemia from ectopic intact parathyroid hormone secretion treated with continuous renal replacement therapy in a patient with two malignancies." BMJ Case Reports 14, no. 6 (2021): e242172. http://dx.doi.org/10.1136/bcr-2021-242172.

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We present a 61-year-old Caucasian woman with endometroid carcinoma as well as a poorly differentiated adenocarcinoma who developed severe hypercalcaemia in the setting of an elevated intact parathyroid hormone. The patient was hospitalised twice for her condition. During her first hospitalisation, she was diagnosed with an endometroid carcinoma and hypercalcaemia. With medical management, she had a normal calcium level on discharge. She presented 3 weeks later with hypercalcaemia and encephalopathy. This time her hypercalcaemia was refractory to medical management, and required continuous ren

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9

Bigsby, Glenn E., Robert W. Holloway, Burkhard Weppelman, Robert B. Reynolds, and Briana Williams. "Endometroid adenocarcinoma of the uterus with cardiac metastasis." Gynecologic Oncology 97, no. 1 (2005): 256–59. http://dx.doi.org/10.1016/j.ygyno.2004.12.052.

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Agrawal, Priti, Rishi Agrawal, Jaswant Jain, and Anandi Lobo. "Postmenopausal endometrial carcinoma presenting as urinary incontinence: a case report." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 10, no. 6 (2021): 2544. http://dx.doi.org/10.18203/2320-1770.ijrcog20212215.

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Endometrial carcinoma (EC) most commonly presents with postmenopausal bleeding (PMB) or blood tinged vaginal discharge. Watery vaginal discharge is usually reported in fallopian tube malignancy. We reported a case of EC where she had profuse watery discharge from private part mimicking urine and so patient visited urologist for urinary incontinence and was later diagnosed as endometroid adenocarcinoma. A 73 year old female presented with history of passing urine involuntarily for last 3 months. Endometrial biopsy revealed endometrial endometroid adenocarcinoma-FIGO grade-2. FDG PET-CT scan rev

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11

Purandare, N., F. Ramli, K. Purcell, M. McCourt, and A. Curtain. "P1084 Endometroid adenocarcinoma in a known case of endometriosis." International Journal of Gynecology & Obstetrics 107 (October 2009): S715. http://dx.doi.org/10.1016/s0020-7292(09)62569-8.

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12

Coventry, P., and R. Balasubramanian. "ENDOMETROID ADENOCARCINOMA OF THE OVARY WITH A PARANEOPLASTIC SYNDROME." International Journal of Clinical Practice 52, no. 6 (1998): 438. http://dx.doi.org/10.1111/j.1742-1241.1998.tb08899.x.

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13

Kato, K., K. Suzuka, T. Osaki, M. Itami, and N. Tanaka. "Primary hepatoid adenocarcinoma of the uterine cervix." International Journal of Gynecologic Cancer 17, no. 5 (2007): 1150–54. http://dx.doi.org/10.1111/j.1525-1438.2007.00901.x.

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Hepatoid adenocarcinoma is characterized histologically by neoplastic epithelial cells that resemble hepatocellular carcinoma (HCC) and produce alpha-fetoprotein (AFP). We describe a case of hepatoid adenocarcinoma of the uterus that, unlike any other previously reported case, was strictly confined to the cervix. A cervical biopsy demonstrated poorly differentiated adenocarcinoma, and hysterectomy and bilateral salpingo-oophorectomy were subsequently performed. Histologically, the lesion consisted of solid sheets of hepatoid cells accompanied with areas of endometroid adenocarcinoma. The tumor

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Gul, Shaista, Syed Muhammad Ishaque, Shafi Muhmmad Khosa, Shahid Zafar, Ahmad Ali Khan, and Abdullah Jan Panezai. "Detection of BRCA-1 gene mutations in epithelial ovarian tumors at tertiary care hospital Karachi." International Journal of Pathology 22, no. 3 (2024): 133–40. http://dx.doi.org/10.59736/ijp.22.03.917.

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ABSTRACT Background: Ovarian cancer is the most common and lethal gynecological malignancy. Ovarian malignancy is the 3rd most common cancer in Pakistan. More than 90% ovarian cancers are of epithelial cell origin, about 24-40% such cancers have hereditary or sporadic mutation in the BRCA-1 or BRCA-2 genes. The present study was designed to detect BRCA-1 gene mutations in different histological sub-types of epithelial origin of benign, borderline and malignant ovarian tumors. Methods: This cross-sectional study was based on the analysis of BRCA-1 gene mutations in the epithelial origin of beni

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Abuzoda, U., and J. Preston. "A case of bilateral primary endometroid adenocarcinoma of the fallopian tubes." Journal of Obstetrics and Gynaecology 22, no. 5 (2002): 571–72. http://dx.doi.org/10.1080/014436102760299006.

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16

Palit, A., H. McDowell, H. Carty, R. Rintala, and G. Kokai. "Endometroid adenocarcinoma of the cervix in a 9-year-old girl." British Journal of Radiology 71, no. 850 (1998): 1093–95. http://dx.doi.org/10.1259/bjr.71.850.10211073.

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17

Kim, Grace, and David Y. Lo. "S3288 Rectal EUS-FNB in the Evaluation of Recurrent Endometroid Adenocarcinoma." American Journal of Gastroenterology 118, no. 10S (2023): S2181. http://dx.doi.org/10.14309/01.ajg.0000962792.08090.b6.

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18

Velayutham, Sumathi, Indumati B., and Pratap Vishnu. "A Case Study on Different Morphological Patterns and Incidence of Synchronous Endometrial Carcinoma in A Tertiary Care Centre." International Journal of Toxicological and Pharmacological Research 13, no. 7 (2023): 223–27. https://doi.org/10.5281/zenodo.11115416.

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<strong>Introduction:</strong> Endometrial Adenocarcinoma by far is the most common malignant tumors of the uterine corpus, which are divided into endometroid and special variant types. It is frequently observed in elderly age group with varied morphological patterns. The objective of this study is to delineate different histologic presentation and associated condition with endometrial carcinoma. <strong>Aim</strong><strong>:</strong> The aim of the study is to delineate different morphological presentation associated with endometrial carcinoma. To differentiate other aggressive

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Maradová, Eliška, Martin Janošík, Radovan Pilka, and Radim Marek. "Metastatic involvement of inguinal lymph nodes as the first sign of endometroid carcinoma of the fallopian tube." Česká gynekologie 87, no. 5 (2022): 328–32. http://dx.doi.org/10.48095/cccg2022328.

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Manifestation of ovarian carcinoma in the form of inguinal lymph node involvement represents a rare clinical situation described only by a limited number of case reports. Similarly, extraperitoneal dissemination of the tumor in the absence of advanced abdominal disease is uncommon. We report a 58-year-old female patient with a positive family history of ovarian cancer referred for lymph node enlargement in the left groin and elevation of CA 125. An ultrasound examination of the patient’s left groin revealed an enlarged lymph node of a size 4 × 3 cm, the biopsy of which confirmed a metastatic a

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20

Sauer, Stephanie Tina, Henner Huflage, Sara Aniki Christner, et al. "Preliminary Experience with Virtual Monoenergetic Imaging and Iodine Mapping in the Primary Staging of Endometrial Cancer." Cancers 16, no. 6 (2024): 1229. http://dx.doi.org/10.3390/cancers16061229.

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This study investigated whether virtual monoenergetic images (VMIs) and iodine mapping based on dual-energy CT (DECT) provide advantages in the assessment of endometrial cancer. A dual-source DECT was performed for primary staging of histologically proven endometrioid adenocarcinoma in 21 women (66.8 ± 12.0 years). In addition to iodine maps, VMIs at 40, 50, 60, 70, and 80 keV were reconstructed from polyenergetic images (PEIs). Objective analysis comprised the measurement of tumor contrast, contrast-to-noise ratio, and normalized iodine concentration (NIC). In addition, three radiologists ind

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21

Kathuria, Priyanka. "#331 : Bilateral Endometriomas Masquerading Synchronous Endometrial and Ovarian Cancer (SEOC) in an Infertile Female." Fertility & Reproduction 05, no. 04 (2023): 512–13. http://dx.doi.org/10.1142/s2661318223742753.

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Background and Aims: Endometriomas are diagnosed in clinical practice by imaging (mostly ultrasound) in females presenting with infertility. CA-125 level is an adjuvant investigation which may be indicative of endometriosis. A few research questions that are yet to be answered. Is ultrasound a sufficient modality to diagnose endometrioma? Is there any cut off as far as the measurement of endometrioma is concerned to step up the imaging modality to MRI? Synchronous endometrial and ovarian cancer (SEOC) is a rare phenomenon with an incidence of 1.4 - 3.8%. Mostly in SEOC, the ovarian endometroid

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22

Yee, Francis Zheng Yi, Grace Hwei Ching Tan, Claramae Shulyn Chia, Khee Chee Soo, and Melissa Ching Ching Teo. "Uncommon indications for cytoreductive surgery and hyperthermic intraperitoneal chemotherapy." Pleura and Peritoneum 2, no. 3 (2017): 129–36. http://dx.doi.org/10.1515/pp-2017-0017.

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AbstractBackgroundCytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) has changed treatment for selected patients with peritoneal metastases (PM) arising from appendiceal, colorectal, epithelial ovarian, primary peritoneal and gastric cancers. However, the results of CRS with HIPEC remain unclear in PM from other tumor histologies.MethodsWe report a series of 10 patients who underwent CRS and HIPEC between 2006 and 2015, for PM arising from uncommon tumor origins.ResultsTen patients with PM from uncommon tumor origins underwent CRS and HIPEC. Median age was 46.5

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23

Anandita, Dr, Dr Indu R. Nair, and Dr Anupama Rajanbabu. "Synchronous type ii endometroid adenocarcinoma of the ovary and endometrium: A case report." International Journal of Clinical Obstetrics and Gynaecology 4, no. 5 (2020): 96–98. http://dx.doi.org/10.33545/gynae.2020.v4.i5b.689.

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24

QUDDUSI, H., A. R. ADIL, and S. ANWAR. "Clinical Experience of Patients Presenting with Epithelial Ovarian Carcinoma." Annals of King Edward Medical University 11, no. 2 (2021): 71–73. https://doi.org/10.21649/akemu.v11i2.4231.

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Aims: We present our experience with epithelial ovarian carcinoma, its histopathology and relationship with age, parity and breast-feeding practices as seen in our clinical practice. Design: Descriptive study. Place and Duration of study: All diagnosed cases of ovarian epithelial carcinoma during January 2001 to December 2002 in obstetrics and gynecology unit II of Nishter Hospital Multan and MINAR (Multan Institute of Nuclear Medicine and Radiotherapy) were included in this study. Subject and Methods: Clinical records of diagnosed cases of ovarian carcinoma were reviewed and data relating to

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Jansen, Kristina, Lara Kornfeld, Maximilian Lennartz, et al. "Carcinoembryonic antigen (CEA) expression in human tumors: A tissue microarray study on 15,413 tumors." Journal of Clinical Oncology 41, no. 16_suppl (2023): e15181-e15181. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.e15181.

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e15181 Background: Carcinoembryonic antigen (CEA) is a cell surface glycoprotein which is overexpressed in various cancers but reported prevalence data vary considerably for many tumor types. Because of its overexpression in various cancer types and the limited expression in normal tissue CEA has become a potential drug target with several potential drug candidates currently being evaluated. CEA is also shed into the blood stream, so that CEA measurement in the serum is used as a tool for early detection and recurrence monitoring of cancer. Methods: To comprehensively determine CEA expression

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A., Zahida O., Mohammad Niaz, and Krishnaraj Upadhyaya. "Study of malignant tumours of the uterine corpus: histopathology and immunohistochemistry." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 9, no. 9 (2020): 3843. http://dx.doi.org/10.18203/2320-1770.ijrcog20203867.

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Background: The uterine corpus represents the second most common site for malignancy in the female genital tract. This study was performed to ascertain the profile of malignant tumours of the uterine corpus reported at our centre.Methods: A retrospective analysis of cases retrieved from the archives of the department of pathology from January 2014 to December 2016. Clinical information of the patients was collected from the hospital records. Classification and grading of the tumours were done according to the current WHO classification.Results: Nineteen cases were studied. There were ten cases

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Subedi, Kirtipal, Meeta Singh, and Neebha Ojha. "Histopathological Pattern of Gynecological Malignancy at Tribhuvan University Teaching Hospital, Nepal." Nepal Journal of Obstetrics and Gynaecology 12, no. 2 (2018): 44–47. http://dx.doi.org/10.3126/njog.v12i2.19952.

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Aims: This study aims to find out histopathological diagnosis and stage at presentation during the diagnosis of female genital tumors.Methodology: This is hospital based prospective observational study of histopathologically confirmed gynecological malignancies conducted in the Department of Obstetrics and Gynecology, TUTH, Maharajgunj, Kathmandu for one year from 2014 to 2015Results: Among 102 cases enrolled in the study, the most common gynecological malignancy was of ovary (48%) followed by cervix (31%), endometrium (11%), vulval (6%), gestational trophoblastic neoplasia (3%) and fallopian

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PAPATHANASIOU, K., A. TOLIKAS, D. DOVAS, E. KOSTOPOULOU, N. FRAGKEDAKIS, and J. TZAFETTAS. "Simultaneously detected primary malignant tumors of ovary and endometrium with unusual histology." International Journal of Gynecologic Cancer 15, no. 6 (2005): 1191–94. http://dx.doi.org/10.1136/ijgc-00009577-200511000-00037.

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A case of a mucinous adenocarcinoma of the ovary with a synchronous endometroid tumor of the endometrium with focal features of undifferentiated carcinoma and deep myometrial invasion is reported. A review of the literature revealed that our case is interesting in view of the fact that simultaneous presentation of primary ovarian and endometrial neoplasms is rare and usually related to low-stage ovarian lesions and well-differentiated and superficial endometrial carcinomas in contrast to our case with the focal features of undifferentiated carcinoma and the deep myometrial invasion. These doub

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Jain, D., F. Zaiem, C. Ballouk, and S. Bandyopadhyay. "INTRAOPERATIVE FROZEN SECTION ANALYSIS OF ENDOMETRIOID OVARIAN BORDERLINE TUMOR: A DIFFICULT DIAGNOSIS." American Journal of Clinical Pathology 160, Supplement_1 (2023): S52. http://dx.doi.org/10.1093/ajcp/aqad150.117.

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Abstract Introduction/Objective Borderline ovarian tumors (BOT) comprise approximately 15% of all primary ovarian neoplasms; of these endometroid borderline ovarian tumors (EBOT) are much rarer (2-3%). BOT is often potentially misdiagnosed as a malignant tumor based on its challenging histomorphological features and thus, treated aggressively. Herein, we present an unusual case of EBOT with adenofibromatous pattern in a 50-year-old gravida 3, para 2 female diagnosed on intraoperative frozen sections (IOFS). Methods/Case Report Patient with history of endometriosis presented with left lower qua

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Pun, Chin Bahadur, Sadina Shrestha, Ranjan Raj Bhatta, et al. "An Overview of Ovarian Tumours at B.P. Koirala Memorial Cancer Hospital, Nepal." Nepalese Journal of Cancer 3, no. 1 (2019): 44–48. http://dx.doi.org/10.3126/njc.v3i1.25915.

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Introduction: Ovarian cancer is the seventh most commonly diagnosed cancer among women in the world. This study was conducted with the aim to find out different histological types of ovarian tumours reported at B.P. Koirala Memorial Cancer Hospital (BPKMCH), Chitwan, Nepal. Methods: This was a retrospective study carried out at the Department of Pathology of BPKMCH from January 1, 2018 to December 31, 2018. This study included the patients who were operated at BPKMCH or referred cases from elsewhere, but the specimen was processed and reported at BPKMCH. All the data were retrieved and a

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Dessources, K., A. D. C. Paula, P. Cybulska, et al. "Whole-exome sequencing and clonal evolution of brain metastases in low-grade early-stage endometroid endometrial adenocarcinoma." Gynecologic Oncology 159 (October 2020): 222–23. http://dx.doi.org/10.1016/j.ygyno.2020.05.369.

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Kanika, Jain, Chopra Kanika, Dutta Debasis, and Nigam Rashmi. "NEUROENDOCRINE CARCINOMA OF THE UTERUS." International Journal of Medical Research and Pharmaceutical Sciences 4, no. 8 (2017): 14–19. https://doi.org/10.5281/zenodo.841166.

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Neuroendocrine carcinoma of the cervix and endometrium are very rare and aggressive tumours. The present case study is of a 52 year old female who was a known case of hypertension and diabetes mellitus and presented to Sir Ganga Ram Hospital with postmenopausal bleeding per vaginum with moderately differentiated adenocarcinoma reported on endometrial biopsy done outside. Patient underwent total Laparoscopic Radical Hysterectomy with staging and bilateral pelvic lymphadenectomy. Her final FIGO staging was stage Ib. Histopathology confirmed poorly differentiated endometroid carcinoma of fundus

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Shaikh, Naseer Ahmed, Farzana Memon, and Rukhsana Parveen Samro. "TUMOR MARKERS." Professional Medical Journal 21, no. 04 (2018): 621–27. http://dx.doi.org/10.29309/tpmj/2014.21.04.2290.

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Object: Analysis of serum tumor markers CA-125, CEA, AFP, & ß-HCG in patientswith ovarian malignant tumors and correlation of their serum levels with histological types. StudyDesign: Institution based descriptive and prospective study. Place & Duration: Department ofPathology, Liaquat University of Medical & Health Sciences, Jamshoro from January 2009 toJune 2011. Material & Methods: One hundred cases, diagnosed as ovarian malignant tumor onH&E staining were selected for study & measurement of serum CA-125, CEA, AFP, & ß-HCGpreoperatively and postoperatively in each

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Shafiee, Mohamad Nasir, Lim Pei Shan, Shuhaila Ahmad, Nazimah Idris, and Mohd Hashim Omar. "The use of gonadotrophin-releasing hormone (GnRH) analogue in endometroid adenocarcinoma of the ovary: a case report and discussion." European Journal of Obstetrics & Gynecology and Reproductive Biology 161, no. 1 (2012): 110–11. http://dx.doi.org/10.1016/j.ejogrb.2011.11.014.

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Der, EM, K. Adu-Bonsaffoh, Y. Tettey, et al. "Clinico-pathological characteristics of cervical cancer in Ghanaian women." Journal of Medical and Biomedical Sciences 3, no. 3 (2015): 27–32. http://dx.doi.org/10.4314/jmbs.v3i3.5.

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Cervical cancer is a major cause of cancer related mortality in the developing countries, although preventable. The aim of this study was to use a retrospective descriptive study to determine the prevalence and the clinico-pathological characteristics of cervical cancer among genital tract ma-lignancies. This study reviewed all histologically confirmed female genital tract malignancies for cervical cancers from January 2002 to December 2011. The clinico-pathological features of women with cervical cancer were analyzed using SPSS software (version 18). A total of 1011(70.8%) out of 1,427 female

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Gercovich, N., S. Carnaval, F. Negro, et al. "Ovarian adenocarcinoma in teenagers and young adults: A clinical challenge." Journal of Clinical Oncology 25, no. 18_suppl (2007): 16070. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.16070.

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16070 Background: Ovarian cancer (OC) appears at an average age of 63, and is uncommon in younger patients (pt), with only about 5% being diagnosed below 30 years of age. The aim of this study is to analyze the onset and prognosis of ovarian adenocarcinoma (OA) in teenagers and young adults treated at the IOHM. Methods: From Oct 87 through Nov 06, 467 pt were diagnosed with OC. Twenty six pt (5,35%) were young adults or teenagers. Ten out of the 26 pt had OA, while the other histological types were as follows: 7 pt Germ cell tumors- 5 pt Borderline - 2 pt stromal tumors - 1 pt neuroendocrine -

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Kumari, Khusboo, Manoj Kumar Paswan, Meghraj Kundan, and Shivlok N. Ambedkar. "A prospective study of endometrial histopathology in post-menopausal women in Jharkhand." Journal of Family Medicine and Primary Care 13, no. 5 (2024): 1696–700. http://dx.doi.org/10.4103/jfmpc.jfmpc_1331_23.

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ABSTRACT Introduction: Postmenopausal bleeding (PMB) refers to any uterine bleeding in a menopausal women. In the early menopausal years, endometrial hyperplasia, polyps and submucosal fibroids are common etiologies of post menopausal bleeding. The most common cause of postmenopausal bleeding is endometrial atrophy, comprises of 60-80%, while endometrial hyperplasia and endometrial cancer contribute to only 11% of Post menopausal bleeding. The aim of study is to analyses histomorphological pattern of endometrium in patients presenting with post-menopausal bleeding in Jharkhand. Materials and M

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Ayala Morales, Fernando, Geraldina Suyapa Gómez, Heriberto Rodríguez Gudiel, and Edwin Rodríguez Guzmán. "Cáncer de endometrio. Reporte de un caso y revisión de la literatura." Revista Médica Hondureña 86, no. 3-4 (2018): 119–22. http://dx.doi.org/10.5377/rmh.v86i3-4.12175.

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Antecedentes: El cáncer endometrial (CE) según las estadísticas es el tumor ginecológico más frecuente en países desarrollados, donde su incidencia ha ido en aumento. Históricamente, el CE se ha clasificado en dos tipos: Tipo I (endometrioide), representando el 80-90% de los casos; el tipo II (no endometrioide como el de células serosas y claras, carcinomas indiferenciados). Como dato importante, la mayoría de las pacientes son diagnosticadas cuando la enfermedad se encuentra en etapas tempranas o la lesión todavía está confinada al útero. El tratamiento convencional radica en una histerectomí

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Pirog, Edyta Catalina. "Primary Adenocarcinoma of the Uterine Cervix: Classification and Grading." AJSP: Reviews and Reports 23, no. 2 (2018): 62–72. http://dx.doi.org/10.1097/pcr.0000000000000232.

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Abstract Cervical adenocarcinomas are a group of malignancies with several distinct histologic tumor types, which include endocervical usual type, endometrioid, intestinal, villoglandular, gastric, signet ring, serous, clear cell, and mesonephric. Diagnosis of cervical adenocarcinoma, in particular early diagnosis, and classification of the tumor type may pose a significant challenge. The goal of this article is to review the current classification, diagnostic criteria, adjunct markers, and differential diagnosis of various subtypes of cervical adenocarcinomas. The article presents up-to-date

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Yan, Bin, Tingting Zhao, Xiufen Liang, Chen Niu, and Caixia Ding. "Can the apparent diffusion coefficient differentiate the grade of endometrioid adenocarcinoma and the histological subtype of endometrial cancer?" Acta Radiologica 59, no. 3 (2017): 363–70. http://dx.doi.org/10.1177/0284185117716198.

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Background Diffusion-weighted imaging (DWI) provides useful information for the identification of benign and malignant uterine lesions. However, the use of the apparent diffusion coefficient (ADC) for histopathological grading of endometrial cancer is controversial. Purpose To explore the use of ADC values in differentiating the preoperative tumor grading of endometrioid adenocarcinomas and investigate the relationship between the ADC values of endometrial cancer and the histological tumor subtype. Material and Methods We retrospectively evaluated 98 patients with endometrial cancers, includin

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Corey, Logan, Michele L. Cote, Julie J. Ruterbusch, and Ira Seth Winer. "Disparities in adjuvant treatment of high-grade endometrial cancer." Journal of Clinical Oncology 39, no. 15_suppl (2021): e17572-e17572. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e17572.

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e17572 Background: To examine surgical outcomes, patterns of adjuvant therapy, and survival for non-Hispanic Black (NHB) women compared to non-Hispanic White (NHW) and Hispanic (HS) women who have undergone surgery for high grade endometrial cancer in the Medicare population. Methods: We utilized the SEER-Medicare linked database to identify women who underwent surgery as a primary treatment for uterine grade 3 endometrioid adenocarcinoma, carcinosarcoma, clear cell carcinoma, or serous carcinoma between the years 2000 and 2015. Multinomial logistic regression was used to estimate odds ratios

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Gharib, Fatma, Dareen Abd elaziz mohamed, and Basma Saed Amer. "Expression of L1CAM and KI-67 in Endometrial Cancer of Egyptian Females: Clinical Impact and Survival." Tumori Journal 106, no. 1_suppl (2020): 36. http://dx.doi.org/10.1177/0300891620914173.

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Introduction: Endometrial adenocarcinoma is characterized by a good prognosis. However, the disease response shows a significant heterogeneity. Treatment of endometrial cancer (EC) is still based on clinico-pathological parameters, which have limited role in risk stratification. There is a need for more determinant markers, such as L1 Cell Adhesion Molecule (L1CAM), to identify patients at higher risk of relapse and tailor a more convenient treatment. L1CAM has a capacity to enhance cell motility and promote tumor invasion in different malignancies. In Egypt, the incidence rate of EC is growin

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Gontijo, Lorayne Cardoso, Renata Margarida Etchebehere, Luís Ronan Marquez Ferreira de Souza, Eddie Fernando Candido Murta, and Rosekeila Simões Nomelini. "Endometrioid adenocarcinoma with sacral metastasis." Česká gynekologie 89, no. 4 (2024): 298–303. http://dx.doi.org/10.48095/cccg2024298.

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Most bone tumors are metastatic. Breasts, lungs, kidneys, and thyroid are the primary sites most commonly involved in bone metastasis-type outcomes. This case study describes the involvement of a patient with a bone tumor located in the axial skeleton, initially in the sacral region. However, the primary site was undefined. Therefore, it was necessary to expand the investigation with immunohistochemistry, which demonstrated a metastatic tumor compatible with endometrioid adenocarcinoma. But even after examination, no active lesion was found in the endometrial region. The study was observationa

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Azhar, Musa, Shafquat Ali Khan, Syed Abdul Manan Hamdani, et al. "Survival Outcomes in the Patients of Ovarian Epithelial Carcinomas Treated with Fertility-Sparing Surgery: A Study from a Developing Country." Pakistan Armed Forces Medical Journal 72, no. 5 (2022): 1597–601. http://dx.doi.org/10.51253/pafmj.v72i5.5218.

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Objective: To assess the outcomes of fertility-sparing surgery in patients with ovarian epithelial carcinoma treated at our centre. Study Design: Retrospective longitudinal study. Place and Duration of Study: Shaukat Khanum Memorial Cancer Hospital & Research Center, Lahore Pakistan, from Jul 2001 to Aug 2015. Methodology: We studied 31 patients with ovarian epithelial carcinoma who underwent fertility-sparing surgery at Shaukat Khanum Memorial Hospital. The detail regarding patients and tumour characteristics, along with outcomes of the intervention, was obtained from se

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Savchenko, P. V., I. S. Shponka, P. O. Hrytsenko, and O. A. Savchenko. "Proliferation activity and hormonal status of atypical hyperplasia and endometrioid adenocarcinoma of the endometrium." Pathologia 21, no. 1 (2024): 51–56. http://dx.doi.org/10.14739/2310-1237.2024.1.299170.

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Atypical hyperplasia of the endometrium is a precancerous condition for endometrioid adenocarcinoma of the endometrium, which is the largest group among malignant neoplasms of the uterine body, according to the Cancer Registry, the mortality rate from which took the 3rd place in 2021. The absence of specific clinical manifestations complicates diagnostics at the early stages of the process, which necessitates the study of histological and immunohistochemical criteria to verify the diagnosis. The aim of the study. To improve the differential diagnostic morphological and immunohistochemical crit

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Pirog, Edyta C. "Cervical Adenocarcinoma: Diagnosis of Human Papillomavirus–Positive and Human Papillomavirus–Negative Tumors." Archives of Pathology & Laboratory Medicine 141, no. 12 (2017): 1653–67. http://dx.doi.org/10.5858/arpa.2016-0356-ra.

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Context.— Cervical adenocarcinomas span a diverse group of tumors with several distinct histologic tumor types, which include endocervical, endometrioid, intestinal, villoglandular, gastric, signet ring, serous, clear cell, and mesonephric. Diagnosis of cervical adenocarcinoma, especially early diagnosis, poses a significant challenge. Objective.— To review the pathogenesis, diagnostic criteria, immunohistochemical markers, and differential diagnosis of various subtypes of human papillomavirus (HPV)–positive and HPV-negative cervical adenocarcinomas. The paper presents a concise summary of the

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Savchenko, P. V., I. S. Shponka, and P. O. Hrytsenko. "Immunohistochemical profile of endometrioid adenocarcinomas of various degrees of morphological atypism." Morphologia 18, no. 3 (2024): 110–16. https://doi.org/10.26641/1997-9665.2024.3.110-116.

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Topicality. Endometrioid adenocarcinoma of the endometrium is a significant part of malignant neoplasms of the uterine body, which, in turn, are the 2nd most common in menopausal women in 2022, according to the Cancer Registry of Ukraine. The absence of a specific clinical picture, similarity to other variants of adenocarcinoma of the uterine body necessitates the study of histological and immunohistochemical criteria to determine the degree of morphological atypism. Purpose. To improve the differential diagnostic immunohistochemical criteria for the diagnosis of endometrioid adenocarcinoma of

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Agustin Batz, Osman, Victor Argueta, Hector De Paz, Walter O. Vasquez Bonilla, and Roberto Orozco. "Adenocarcinoma de endometrio en pacientes menores de 30 años." Revista médica (Colegio de Médicos y Cirujanos de Guatemala) 158, no. 2 (2019): 106–10. http://dx.doi.org/10.36109/rmg.v158i2.138.

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Introducción: El adenocarcinoma de endometrio es el más común de los carcinomas endometriales, siendo la edad media de diagnóstico los 61 años; sin embargo, hasta 2-14% puede ser diagnosticado antes de la menopausia. Los factores de riesgo son la nuliparidad, exposición a estrógenos, obesidad, síndrome de Stein Leventhal, entre otros. Material y métodos: Estudio descriptivo retrospectivo de 6 casos de pacientes menores de 30 años, estudiadas en el departamento de Patología del Hospital General San Juan de Dios de la ciudad de Guatemala, entre 2009 y 2019 con diagnóstico de adenocarcinoma

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Maksem, John. "Endometrial Tumors with “Shadow Cells” Intimate a Neoplastic Potential for Morules or Their Progenitors in β-Catenin Mutated Endometrial Adenocarcinomas." Journal of Clinical Obstetrics and Gynecology Research 6, № 1 (2024): 1–7. http://dx.doi.org/10.52338/jocogr.2024.3999.

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Background : Several features are shared by endometrial morules and pilomatrixoma-like endometrial carcinomas including CDX-2 and β-catenin nuclear staining, absence of p63 and p40 nuclear staining, and a unique form of endepithelial differentiation that produces so-called shadow cells. Both endometrial morules and pilomatrixoma-like endometrial carcinomas may be associated with low-grade endometrioid adenocarcinoma. Methods : We present 11 fully staged endometrioid endometrial adenocarcinomas that showed extrauterine metastases (Stages III and IV), morules, shadow cell differentiation, and nu

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Miller, Kathryn, Olga T. Filippova, Sara A. Hayes, et al. "Pattern of disease in recurrent cervical cancer associated with response to pembrolizumab." Journal of Clinical Oncology 38, no. 15_suppl (2020): e18006-e18006. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e18006.

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e18006 Background: Pembrolizumab received accelerated FDA approval for treatment of metastatic or recurrent PD-L1 positive cervical cancer in 6/2018. Since then, the clinical characteristics of patients who best respond to this immunotherapy have remained undefined. We sought to describe patients with advanced cervical cancer who derived durable clinical benefit (DCB) from pembrolizumab therapy. Methods: Patients with advanced or recurrent cervical cancer who received pembrolizumab from 8/2017-12/2019 at our institution were assessed. Reviewed data included patient demographics, treatment hist

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