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Journal articles on the topic 'Endplate'

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1

Duran, Semra, Mehtap Cavusoglu, Hatice Gul Hatipoglu, Deniz Sozmen Cılız, and Bulent Sakman. "Association between Measures of Vertebral Endplate Morphology and Lumbar Intervertebral Disc Degeneration." Canadian Association of Radiologists Journal 68, no. 2 (May 2017): 210–16. http://dx.doi.org/10.1016/j.carj.2016.11.002.

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Purpose The aim of this study was to evaluate the association between vertebral endplate morphology and the degree of lumbar intervertebral disc degeneration via magnetic resonance imaging (MRI). Methods In total, 150 patients who met the inclusion criteria and were 20–60 years of age were retrospectively evaluated. Patients were evaluated for the presence of intervertebral disc degeneration or herniation, and the degree of degeneration was assessed at all lumbar levels. Vertebral endplate morphology was evaluated based on the endplate sagittal diameter, endplate sagittal concave angle (ECA),
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2

Nagaraja, Srinidhi, Hassan K. Awada, Maureen L. Dreher, John T. Bouck, and Shikha Gupta. "Effects of vertebroplasty on endplate subsidence in elderly female spines." Journal of Neurosurgery: Spine 22, no. 3 (March 2015): 273–82. http://dx.doi.org/10.3171/2014.10.spine14195.

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OBJECT The aim in this study was to quantify the effects of vertebroplasty on endplate subsidence in treated and adjacent vertebrae and their relationship to endplate thickness and underlying trabecular bone in elderly female spines. METHODS Vertebral compression fractures were created in female cadaveric (age range 51–88 years) thoracolumbar spine segments. Specimens were placed into either the control or vertebroplasty group (n = 9/group) such that bone mineral density, trabecular microarchitecture, and age were statistically similar between groups. For the vertebroplasty group, polymethylme
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3

Chen, Xiaofeng, Weijun Guo, Hao Li, Xi Li, Zhuangxun Han, Xueyuan Chu, Zehui Lao, Junxian Xie, and Dongling Cai. "Evaluation of Cartilaginous Endplate Degeneration Based on Magnetic Resonance Imaging." Journal of Healthcare Engineering 2021 (March 23, 2021): 1–12. http://dx.doi.org/10.1155/2021/5534227.

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In order to carry out the evaluation of cartilaginous endplate degeneration based on magnetic resonance imaging (MRI), this paper retrospectively analyzed the MRI data from 120 cases of patients who were diagnosed as lumbar intervertebral disc degeneration and underwent MRI examinations in the designated hospital of this study from June 2018 to June 2020. All cases underwent conventional sagittal and transverse T1WI and T2WI scans, and some cases were added with sagittal fat-suppression T2WI scans; then, the number of degenerative cartilaginous endplates and its ratio to degenerative lumbar in
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Liu, Sijing, Qiong Wang, Ziyi Li, Lei Ma, Ting Li, Yukun Li, Na Wang, Chang Liu, Peng Xue, and Chuan Wang. "TRPV1 Channel Activated by the PGE2/EP4 Pathway Mediates Spinal Hypersensitivity in a Mouse Model of Vertebral Endplate Degeneration." Oxidative Medicine and Cellular Longevity 2021 (August 21, 2021): 1–16. http://dx.doi.org/10.1155/2021/9965737.

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Low back pain (LBP) is the primary cause of disability globally. There is a close relationship between Modic changes or endplate defects and LBP. Endplates undergo ossification and become highly porous during intervertebral disc (IVD) degeneration. In our study, we used a mouse model of vertebral endplate degeneration by lumbar spine instability (LSI) surgery. Safranin O and fast green staining and μCT scan showed that LSI surgery led to endplate ossification and porosity, but the endplates in the sham group were cartilaginous and homogenous. Immunofluorescent staining demonstrated the innerva
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5

Yao, Qi, Peng Yin, Kamran Khan, Tsung-Yuan Tsai, Jing-Sheng Li, Yong Hai, Peifu Tang, and Guoan Li. "Differences of the Morphology of Subaxial Cervical Spine Endplates between Chinese and White Men and Women." BioMed Research International 2018 (2018): 1–8. http://dx.doi.org/10.1155/2018/2854175.

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Objective. The aim of this comparative anatomical study was to specifically investigate endplate morphology differences between Chinese and White men and women. Materials and Methods. Three-dimensional cervical endplate models were constructed using computed tomography imaging of 41 healthy Chinese and 24 White subjects. The morphologic measurements of cervical endplate included linear parameters (EPWu: upper endplate width; EPDu: upper endplate depth; EPWl: lower endplate width; and EPDl: lower endplate depth) and area parameters with a digital measuring system. Results. All linear parameters
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6

Herrero, Carlos Fernando P. S., Sergio Britto Garcia, Luis Vicente Garcia, and Helton Luiz Aparecido Defino. "Endplates Changes Related to Age and Vertebral Segment." BioMed Research International 2014 (2014): 1–6. http://dx.doi.org/10.1155/2014/545017.

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Endplate separations are defined as the presence of a space between the hyaline cartilage and the cortical bone of the adjacent vertebral body. This study evaluates endplate separations from the vertebral body and intervertebral discs and verifies if endplate separation is related to age and the spinal level. Groups were formed based on age (20–40 and 41–85 years old) and the vertebral segment (T7-T8 and L4-L5 segments). Histological analysis included assessment of the length of the vertebral endplates, the number and dimensions of the separations, and orientation of the collagen fibers, in th
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7

Chen, Shiming, Junming Jiang, and Liangjiu Jia. "Numerical study on the performance of beam-to-concrete-filled steel tube column joint with adapter-bracket." Advances in Structural Engineering 21, no. 10 (December 27, 2017): 1542–52. http://dx.doi.org/10.1177/1369433217746345.

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An innovative beam-to-column composite joint with adapter-bracket was proposed and its behavior was investigated through finite element analysis. The special adapter-bracket is to facilitate the assembly of the steel box beam and the concrete-filled steel tube column through high-strength blind bolts. In the adapter-bracket, two endplates are welded to the beam and bolted to the column, respectively. First, two finite element models of the bolted extended endplate joint were developed in ABAQUS and validated by available experimental results. Then, based on modified models, parametric analyses
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8

Jensen, T. S., J. S. Sorensen, and P. Kjaer. "Intra- and interobserver reproducibility of vertebral endplate signal (Modic) changes in the lumbar spine: the nordic modic consensus group classification." Acta Radiologica 48, no. 7 (September 2007): 748–54. http://dx.doi.org/10.1080/02841850701422112.

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Background: The lumbar vertebral endplate is considered a potential cause of specific low back pain. However, in relation to future research, there is need for a reliable and detailed magnetic resonance imaging (MRI) protocol to be used in the evaluation of vertebral endplate signal changes. Purpose: To assess the intra- and interobserver reliability of the “Nordic Modic classification” protocol. Material and Methods: MRI scans of 50 individuals representative of the general Danish population aged 40 were evaluated by two observers. Criteria for grading the changes were developed by the Nordic
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9

Desaulniers, Patrice, Pierre-André Lavoie, and Phillip F. Gardiner. "Habitual exercise enhances neuromuscular transmission efficacy of rat soleus muscle in situ." Journal of Applied Physiology 90, no. 3 (March 1, 2001): 1041–48. http://dx.doi.org/10.1152/jappl.2001.90.3.1041.

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Rat motor nerve terminals and the endplates they interact with exhibit changes to varying patterns of use, as when exposed to increased activation in the form of endurance exercise training. The extent to which these changes affect neuromuscular transmission efficacy is uncertain. In this study, the effects of habitual exercise on the electrophysiological properties of neuromuscular transmission in rat soleus muscle were investigated using a novel in situ approach. Consistent with previous reports, miniature endplate potential frequency was enhanced by habitual exercise. Other passive properti
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10

Fung, K., N. D. Hogikyan, S. B. Heavner, D. Ekbom, and E. L. Feldman. "Development and characterisation of an experimental recurrent laryngeal nerve injury model for the study of viral gene therapy." Journal of Laryngology & Otology 122, no. 5 (June 25, 2007): 500–505. http://dx.doi.org/10.1017/s0022215107009097.

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AbstractObjectives:To develop and characterise an experimental model of recurrent laryngeal nerve injury for the study of viral gene therapy.Methods:Twenty rats underwent unilateral recurrent laryngeal nerve injury. After vocal fold mobility was observed, larynges were serially sectioned, and immunohistochemical techniques were employed to stain for neurofilament and motor endplates in order for a blinded investigator to determine the percentage of nerve–endplate contact, as a histological indicator of an intact neuromuscular connection.Results:All animal procedures resulted in complete, ipsil
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11

Simons, David G. "Do Endplate Noise and Spikes Arise from Normal Motor Endplates?" American Journal of Physical Medicine & Rehabilitation 80, no. 2 (February 2001): 134–40. http://dx.doi.org/10.1097/00002060-200102000-00012.

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12

Yoganandan, N., S. Kumaresan, L. Voo, and F. A. Pintar. "Finite Element Model of the Human Lower Cervical Spine: Parametric Analysis of the C4-C6 Unit." Journal of Biomechanical Engineering 119, no. 1 (February 1, 1997): 87–92. http://dx.doi.org/10.1115/1.2796070.

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In this study, a three-dimensional finite element model of the human lower cervical spine (C4-C6) was constructed. The mathematical model was based on close-up CT scans from a young human cadaver. Cortical shell, cancellous core, endplates, and posterior elements including the lateral masses, pedicle, lamina, and transverse and spinous processes, and the intervertebral disks, were simulated. Using the material properties from literature, the 10,371-element model was exercised under an axial compressive mode of loading. The finite element model response agreed with literature. As a logical step
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Niiya, Tomohisa, Eichi Narimatsu, and Akiyoshi Namiki. "Acute Late Sepsis Attenuates Effects of a Nondepolarizing Neuromuscular Blocker, Rocuronium, by Facilitation of Endplate Potential and Enhancement of Membrane Excitability In Vitro." Anesthesiology 105, no. 5 (November 1, 2006): 968–75. http://dx.doi.org/10.1097/00000542-200611000-00018.

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Background Sepsis attenuates the muscle-relaxing effects of nondepolarizing neuromuscular blockers. The authors investigated the effects of acute late sepsis on neuromuscular transmission and neuromuscular actions of rocuronium to clarify the mechanisms by which sepsis attenuates the effects of nondepolarizing neuromuscular blockers. Methods Sepsis was induced by cecal ligation and puncture operation. Endplate potentials, acetylcholine potentials, and electrotonic potentials were recorded from the motor endplates of isolated diaphragms from acute late septic and nonseptic rats. Results (1) Sep
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14

Zhou, Yuan-Li, Tian-Xia Qiu, Qing-Hang Zhang, and Ee-Chon Teo. "THE RELATIONSHIP BETWEEN LOAD TRANSMISSION AND DISC DEGENERATION IN THE THORACOLUMBAR SPINE: A FINITE ELEMENT STUDY." Journal of Musculoskeletal Research 10, no. 03 (September 2006): 121–30. http://dx.doi.org/10.1142/s0218957706001789.

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Degenerative changes to the intervertebral disc structure appear gradually in the aging process, and are likely to affect the fracture patterns of the thoracolumbar vertebral body — a common site of spinal injuries — by changing the mechanical interaction within each motion segment. This study focused on the influence of disc degeneration on the mechanism of load transmission through the thoracolumbar vertebral body. Compressive stresses and ways of load transmission were examined in cases of normal and degenerated discs. The stress analysis was performed using the finite element (FE) method.
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Wegner, Adam M., Yu-Hsuan Chou, Hsiao-Kang Chang, and Tsung-Cheng Yin. "Transforaminal Interbody Impaction of Bone Graft to Treat Collapsed Nonhealed Vertebral Fractures with Endplate Destruction: A Report of Two Cases." Case Reports in Orthopedics 2020 (September 2, 2020): 1–6. http://dx.doi.org/10.1155/2020/8873350.

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Background. A collapsed nonhealed vertebral fracture with endplate destruction is a challenging injury to address, as there is no single definitive treatment. We present two cases using an innovative transforaminal grafting technique to treat these patients. Case Presentation. Case 1: a 72-year-old woman had nonunion of an L1 compression fracture with destruction of both endplates. T12/L1 and L1/L2 transforaminal debridement and impaction of bone graft were performed followed by posterior instrumentation. At three years follow-up, the fusion mass between T12/L1 and L1/L2 was solid and the pati
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16

Antosh, Ivan J., John G. DeVine, Clyde T. Carpenter, Brian J. Woebkenberg, and Stephen M. Yoest. "Magnetic resonance imaging evaluation of adjacent segments after cervical disc arthroplasty: magnet strength and its effect on image quality." Journal of Neurosurgery: Spine 13, no. 6 (December 2010): 722–26. http://dx.doi.org/10.3171/2010.5.spine09721.

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Object Disc arthroplasty is an alternative to fusion following anterior discectomy when treating either cervical radiculopathy or myelopathy. Its theoretical benefits include preservation of the motion segment and the potential prevention of adjacent-segment degeneration. There is a paucity of data regarding the ability to use MR imaging to evaluate the adjacent segments. The purpose of this study was for the authors to introduce open MR imaging as an alternative method in imaging adjacent segments following cervical disc arthroplasty using a Co-Cr implant and to report their preliminary resul
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Oshina, Masahito, Yasushi Oshima, Sakae Tanaka, and K. Daniel Riew. "Radiological Fusion Criteria of Postoperative Anterior Cervical Discectomy and Fusion: A Systematic Review." Global Spine Journal 8, no. 7 (February 11, 2018): 739–50. http://dx.doi.org/10.1177/2192568218755141.

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Study Design: Systematic review. Objectives: Diagnosis of pseudarthrosis after anterior cervical fusion is difficult, and often depends on the surgeon’s subjective assessment because recommended radiographic criteria are lacking. This review evaluated the available evidence for confirming fusion after anterior cervical surgery. Methods: Articles describing assessment of anterior cervical fusion were retrieved from MEDLINE and SCOPUS. The assessment methods and fusion rates at 1 and 2 years were evaluated to identify reliable radiographical criteria. Results: Ten fusion criteria were described.
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Malham, Gregory M., Rhiannon M. Parker, Carl M. Blecher, and Kevin A. Seex. "Assessment and classification of subsidence after lateral interbody fusion using serial computed tomography." Journal of Neurosurgery: Spine 23, no. 5 (November 2015): 589–97. http://dx.doi.org/10.3171/2015.1.spine14566.

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OBJECT Intervertebral cage settling during bone remodeling after lumbar lateral interbody fusion (LIF) is a common occurrence during the normal healing process. Progression of this settling with endplate collapse is defined as subsidence. The purposes of this study were to 1) assess the rate of subsidence after minimally invasive (MIS) LIF by CT, 2) distinguish between early cage subsidence (ECS) and delayed cage subsidence (DCS), 3) propose a descriptive method for classifying the types of subsidence, and 4) discuss techniques for mitigating the risk of subsidence after MIS LIF. METHODS A tot
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Agarwal, Nitin, Michael D. White, Xiaoran Zhang, Nima Alan, Alp Ozpinar, David J. Salvetti, Zachary J. Tempel, David O. Okonkwo, Adam S. Kanter, and D. Kojo Hamilton. "Impact of endplate-implant area mismatch on rates and grades of subsidence following stand-alone lateral lumbar interbody fusion: an analysis of 623 levels." Journal of Neurosurgery: Spine 33, no. 1 (July 2020): 12–16. http://dx.doi.org/10.3171/2020.1.spine19776.

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OBJECTIVEStand-alone lateral lumbar interbody fusion (LLIF) is a useful minimally invasive approach for select spinal disorders, but implant subsidence may occur in up to 30% of patients. Previous studies have suggested that wider implants reduce the subsidence rate. This study aimed to evaluate whether a mismatch of the endplate and implant area can predict the rate and grade of implant subsidence.METHODSThe authors conducted a retrospective review of prospectively collected data on consecutive patients who underwent stand-alone LLIF between July 2008 and June 2015; 297 patients (623 surgical
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Hong, Chang-Zern. "Myofascial Trigger Points: Pathophysiology and Correlation with Acupuncture Points." Acupuncture in Medicine 18, no. 1 (June 2000): 41–47. http://dx.doi.org/10.1136/aim.18.1.41.

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A review is made of recent studies on myofascial trigger points (MTrP) and their mechanism is discussed. Clinical and basic science studies have shown that there are multiple MTrP loci in a MTrP region. A MTrP locus contains a sensory component (sensitive locus) and a motor component (active locus). A sensitive locus is a point from which tenderness or pain, referred pain, and local twitch response can be elicited by mechanical stimulation. Sensitive loci (probably sensitised nociceptors) are widely distributed in the whole muscle, but are concentrated in the endplate zone. An active locus is
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Caldwell, J. H., D. T. Campbell, and K. G. Beam. "Na channel distribution in vertebrate skeletal muscle." Journal of General Physiology 87, no. 6 (June 1, 1986): 907–32. http://dx.doi.org/10.1085/jgp.87.6.907.

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The loose patch voltage clamp has been used to map Na current density along the length of snake and rat skeletal muscle fibers. Na currents have been recorded from (a) endplate membrane exposed by removal of the nerve terminal, (b) membrane near the endplate, (c) extrajunctional membrane far from both the endplate and the tendon, and (d) membrane near the tendon. Na current densities recorded directly on the endplate were extremely high, exceeding 400 mA/cm2 in some patches. The membrane adjacent to the endplate has a current density about fivefold lower than that of the endplate, but about fi
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Lateva, Zoia C., Kevin C. McGill, and M. Elise Johanson. "The innervation and organization of motor units in a series-fibered human muscle: the brachioradialis." Journal of Applied Physiology 108, no. 6 (June 2010): 1530–41. http://dx.doi.org/10.1152/japplphysiol.01163.2009.

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We studied the innervation and organization of motor units in the brachioradialis muscle of 25 normal human subjects. We recorded intramuscular EMG signals at points separated by 15 mm along the proximodistal muscle axis during moderate isometric contractions, identified from 27 to 61 (mean 39) individual motor units per subject using EMG decomposition, and estimated the locations of the endplates and distal muscle/tendon junctions from the motor-unit action potential (MUAP) propagation patterns and terminal standing waves. In three subjects all the motor units were innervated in a single endp
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Qiang, Xuhong, Nianduo Wu, Xu Jiang, Frans Bijlaard, and Henk Kolstein. "Performance assessment on high strength steel endplate connections after fire." Journal of Structural Fire Engineering 8, no. 2 (June 12, 2017): 202–14. http://dx.doi.org/10.1108/jsfe-11-2016-0018.

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Purpose This study aims to reveal more information and understanding on performance and failure mechanisms of high strength steel endplate connections after fire. Design/methodology/approach An experimental and numerical study on seven endplate connections after cooling down from fire temperature of 550°C has been carried out and reported herein. Moreover, the provisions of European design standard for steel structures, Eurocode 3, were validated with test results of high strength steel endplate connections. Findings In endplate connections, a proper design using a thinner high strength steel
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Qiang, Xuhong, Xu Jiang, Frans Bijlaard, and Henk Kolstein. "Performance assessment on high strength steel endplate connections in fire." Journal of Structural Fire Engineering 7, no. 2 (June 13, 2016): 168–78. http://dx.doi.org/10.1108/jsfe-06-2016-013.

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Purpose This paper aims to investigate and assess a perspective of combining high-strength-steel endplate with mild-steel beam and column in endplate connections. Design/methodology/approach First, experimental tests on high strength steel endplate connections were conducted at fire temperature 550°C and at an ambient temperature for reference. Findings The moment-rotation characteristic, rotation capacity and failure mode of high-strength-steel endplate connections in fire and at an ambient temperature were obtained through tests and compared with those of mild-steel endplate connections. Fur
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Barrantes, Francisco J. "Muscle endplate cholinoreceptors." Pharmacology & Therapeutics 38, no. 3 (January 1988): 331–85. http://dx.doi.org/10.1016/0163-7258(88)90010-1.

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Zhang, Zhiming, Yapeng Shang, and Tong Zhang. "An equivalent mechanical model investigating endplates deflection for PEM fuel cell stack." Advances in Mechanical Engineering 13, no. 7 (July 2021): 168781402110300. http://dx.doi.org/10.1177/16878140211030039.

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The aim of this study is to obtain the deflection curve equations of endplates with one to five clamping belts which allows investigating endplates deflection for uniform contact pressure distribution. Based on an equivalent mechanical model for a large fuel cell stack, the effects of the thicknesses of endplates, numbers, and positions of clamping belts are discussed, and the optimal thickness of endplate with different clamping belts is obtained, and moreover the optimal position of intermediate and outer clamping belts on the endplates. Finally, a three-dimensional finite element analysis (
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Chen, Ke, Xiaohua Lv, Wei Li, Fei Yu, Jianjing Lin, Junxuan Ma, and Deming Xiao. "Autophagy Is a Protective Response to the Oxidative Damage to Endplate Chondrocytes in Intervertebral Disc: Implications for the Treatment of Degenerative Lumbar Disc." Oxidative Medicine and Cellular Longevity 2017 (2017): 1–9. http://dx.doi.org/10.1155/2017/4041768.

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Low back pain (LBP) is the leading cause of disability in the elderly. Intervertebral disc degeneration (IDD) was considered as the main cause for LBP. Degeneration of cartilaginous endplate was a crucial harmful factor during the initiation and development of IDD. Oxidative stress was implicated in IDD. However, the underlying molecular mechanism for the degeneration of cartilaginous endplate remains elusive. Herein, we found that oxidative stress could induce apoptosis and autophagy in endplate chondrocytes evidenced by western blot analysis, flow cytometry, immunofluorescence staining, GFP-
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Covault, J., J. M. Cunningham, and J. R. Sanes. "Neurite outgrowth on cryostat sections of innervated and denervated skeletal muscle." Journal of Cell Biology 105, no. 6 (December 1, 1987): 2479–88. http://dx.doi.org/10.1083/jcb.105.6.2479.

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To localize factors that guide axons reinnervating skeletal muscle, we cultured ciliary ganglion neurons on cryostat sections of innervated and denervated adult muscle. Neurons extended neurites on sections of muscle (and several other tissues), generally in close apposition to sectioned cell surfaces. Average neurite length was greater on sections of denervated than on sections of innervated muscle, supporting the existence of functionally important differences between innervated and denervated muscle fiber surfaces. Furthermore, outgrowth was greater on sections of denervated muscle cut from
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Pekmezci, Murat, Jessica A. Tang, Liu Cheng, Ashin Modak, R. Trigg McClellan, Jenni M. Buckley, and Christopher P. Ames. "Comparison of expandable and fixed interbody cages in a human cadaver corpectomy model, Part I: endplate force characteristics." Journal of Neurosurgery: Spine 17, no. 4 (October 2012): 321–26. http://dx.doi.org/10.3171/2012.7.spine12171.

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Object Expandable cages are becoming more popular due in large part to their versatility, but subsidence and catastrophic failure remain a concern. One of the proposed reasons of failure is edge loading of the endplate caused by a mismatch between the sagittal alignment of the motion segment and cage. This in vitro analysis investigates the endplate forces characteristic of expandable and fixed interbody cages in a single-level human cadaver corpectomy model. Methods Ten human thoracolumbar spines (T10–L2, L3–5) were biomechanically evaluated following a single-level corpectomy that was recons
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Gray, William P., Catherine Keohane, and William O. Kirwan. "Motor nerve transplantation." Neurosurgical Focus 7, no. 3 (September 1999): E7. http://dx.doi.org/10.3171/foc.1999.7.3.8.

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The motor nerve transplantation (MNT) technique is used to transfer an intact nerve into a denervated muscle by harvesting a neurovascular pedicle of muscle containing motor endplates from the motor endplate zone of a donor muscle and implanting it into a denervated muscle. Thirty-six adult New Zealand White rabbits underwent reinnervation of the left long peroneal (LP) muscle (fast twitch) with a motor nerve graft from the soleus muscle (slow twitch). The right LP muscle served as a control. Reinnervation was assessed using microstimulatory single-fiber electromyography (SFEMG), alterations i
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Gray, William P., Catherine Keohane, and William O. Kirwan. "Motor nerve transplantation." Journal of Neurosurgery 87, no. 4 (October 1997): 615–24. http://dx.doi.org/10.3171/jns.1997.87.4.0615.

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✓ The motor nerve transplantation (MNT) technique is used to transfer an intact nerve into a denervated muscle by harvesting a neurovascular pedicle of muscle containing motor endplates from the motor endplate zone of a donor muscle and implanting it into a denervated muscle. Thirty-six adult New Zealand White rabbits underwent reinnervation of the left long peroneal (LP) muscle (fast twitch) with a motor nerve graft from the soleus muscle (slow twitch). The right LP muscle served as a control. Reinnervation was assessed using microstimulatory single-fiber electromyography (SFEMG), alterations
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Chen, Jingming, Themba Nyirenda, Liancai Mu, and Stanislaw Sobotka. "Intraoperative 1-Hour Electrical Nerve Stimulation Enhances Outcomes of Nerve–Muscle-Endplate Band Grafting Technique for Muscle Reinnervation." Journal of Reconstructive Microsurgery 33, no. 08 (June 2, 2017): 533–43. http://dx.doi.org/10.1055/s-0037-1602824.

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Background Increasing evidence suggests that 1-hour electrical nerve stimulation during surgery improves nerve regeneration and functional recovery. However, it remains unknown if this approach has beneficial effects on the outcomes of our recently developed nerve–muscle-endplate band grafting-native motor zone (NMEG-NMZ) technique for muscle reinnervation. Methods In this study, NMEG-NMZ transplantation was performed in a rat model. The right sternomastoid muscle was experimentally denervated and immediately reinnervated by implanting a NMEG harvested from the ipsilateral sternohyoid (SH) mus
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Cohen-Gadol, Aaron A., Mark B. Dekutoski, Choll W. Kim, Lynn M. Quast, and William E. Krauss. "Safety of supplemental endplate screws in thoracic pedicle hook fixation." Journal of Neurosurgery: Spine 98, no. 1 (January 2003): 31–35. http://dx.doi.org/10.3171/spi.2003.98.1.0031.

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Object. The AO Universal Spine System thoracic pedicle hook design includes a fixation screw that passes obliquely through the inferior facet into the pedicle to engage in the posterior portion of the superior vertebral body endplate. This endplate screw provides additional purchase at the hook—bone interface. To determine the safety of this fixation system the authors reviewed the operative notes, radiographs, and outcomes of patients who underwent placement of endplate screws. Methods. Thirty-six patients (16 male and 20 female patients) who required posterior thoracic instrumentation for sp
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Sahoo, Madan Mohan, Sudhir Kumar Mahapatra, Sheetal Kaur, Jitendra Sarangi, and Manoranjan Mohapatra. "Significance of Vertebral Endplate Failure in Symptomatic Lumbar Disc Herniation." Global Spine Journal 7, no. 3 (April 20, 2017): 230–38. http://dx.doi.org/10.1177/2192568217694142.

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Study Design: Prospective cohort study. Objective: Endplate lesions though have been implicated in the genesis of lumbar disc herniation (LDH), very little is known regarding their clinical course. Thus, the present study is aimed to investigate the incidence and types of endplate failure (EPF) in LDH and its correlation with the clinical symptoms and prognosis. Methods: Clinical and magnetic resonance imaging (MRI) features of 66 patients with isolated single level LDH were studied. Three-dimensional fast spoiled gradient (3D FSPGR) MRI and computed tomography scans were used to identify the
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35

Olsen, P. C. "Bolted endplate connections revisited." Journal of Constructional Steel Research 58, no. 9 (September 2002): 1265–80. http://dx.doi.org/10.1016/s0143-974x(01)00067-0.

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Hutchinson, David O., Timothy J. Walls, Satoshi Nakano, Shelley Camp, Palmer Taylor, C. Michel Harper, Robert V. Groover, Hamlet A. Peterson, Dara G. Jamieson, and Andrew G. Engel. "Congential Endplate acetylocholinesterase deficiency." Brain 116, no. 3 (1993): 633–53. http://dx.doi.org/10.1093/brain/116.3.633.

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Wang, Yue, Tapio Videman, and Michele C. Battié. "Lumbar Vertebral Endplate Lesions." Spine 37, no. 17 (August 2012): 1432–39. http://dx.doi.org/10.1097/brs.0b013e31824dd20a.

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&NA;. "Mapping the Vertebral Endplate." Back Letter 15, no. 7 (July 2000): 74–75. http://dx.doi.org/10.1097/00130561-200015070-00003.

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Antoniou, John, Nora M. Goudsouzian, Terrence F. Heathfield, Neil Winterbottom, Thomas Steffen, A. Robin Poole, Max Aebi, and Mauro Alini. "The Human Lumbar Endplate." Spine 21, no. 10 (May 1996): 1153–61. http://dx.doi.org/10.1097/00007632-199605150-00006.

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Johnson, Ernest W. "More on Endplate Noise." American Journal of Physical Medicine & Rehabilitation 81, no. 3 (March 2002): 161. http://dx.doi.org/10.1097/00002060-200203000-00001.

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Elfiky, Tarek Anwar, Nirmal Dhananjay Patil, Yasser Allam, and Raafat Ragab. "Endplate Changes with Polyetheretherketone Cages in Posterior Lumbar Interbody Fusion." Asian Spine Journal 14, no. 2 (April 30, 2020): 229–37. http://dx.doi.org/10.31616/asj.2019.0124.

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Study Design: A retrospective radiographic analysis.Purpose: The aim of the current study is to assess endplate changes after the use of polyetheretherketone (PEEK) cages in posterior lumbar interbody fusion (PLIF).Overview of Literature: A few recent reports had revealed endplate abnormalities due to PEEK cages, which may lead to nonunions.Methods: A retrospective computed tomography (CT)-based analysis of the endplate cavities and fusion status following PLIFs with PEEK cages was conducted by two independent observers. The term “cavity” was used to describe the endplate changes. The vertebra
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Ye, Yi, Xucan Wang, Zhenqing Yang, Qian Xu, and Bo Zhang. "Hsp22 Inhibits Oxidative Stress-Induced Endplate Chondrocyte Apoptosis by Regulating Mitochondrial Pathway." Journal of Biomaterials and Tissue Engineering 11, no. 10 (October 1, 2021): 1947–54. http://dx.doi.org/10.1166/jbt.2021.2763.

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Background: Facet joint degeneration (FJD), which is also called facet joint syndrome (FJS), has become one of the most commonly seen etiological factors for lumbago. Cartilage lesion triggered by lumbar facet joint (LFJ) degeneration might be related to mitochondrial impairment, but the its underlying mechanism remains unclear. Materials and methods: The endplate chondrocytes were induced by hydrogen peroxide (H2O2) to mimic the pathological conditions of oxidative stress. Enzyme linked immunosorbent assay (ELISA) were used for the evaluation of reactive oxygen species (ROS). Adenosine-tripho
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Morimoto, Masatoshi, Kosaku Higashino, Shinsuke Katoh, Tezuka Fumitake, Kazuta Yamashita, Fumio Hayashi, Yoichiro Takata, Toshinori Sakai, Akihiro Nagamachi, and Koichi Sairyo. "A Rare Case of Progressive Palsy of the Lower Leg Caused by a Huge Lumbar Posterior Endplate Lesion after Recurrent Disc Herniation." Case Reports in Orthopedics 2016 (2016): 1–4. http://dx.doi.org/10.1155/2016/5963924.

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A lesion of the lumbar posterior endplate is sometimes identified in the spinal canal of children and adolescents; it causes symptoms similar to those of a herniated disc. However, the pathology of the endplate lesion and the pathology of the herniated disc are different. We present a rare case of a 23-year-old woman who developed progressive palsy of the lower leg caused by huge lumbar posterior endplate lesion after recurrent disc herniation.
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Rothschild, Bruce M., Jonhan Ho, and Yossef Masharawi. "Macroscopic anatomy of the vertebral endplate: Quid significat?" Anthropologischer Anzeiger 71, no. 3 (June 1, 2014): 191–217. http://dx.doi.org/10.1127/0003-5548/2014/0365.

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45

Eijkelkamp, M. F., J. Hayen, A. G. Veldhuizen, J. R. Van Horn, and G. J. Verkerke. "Improving the Fixation of an Artificial Intervertebral Disc." International Journal of Artificial Organs 25, no. 4 (April 2002): 327–33. http://dx.doi.org/10.1177/039139880202500412.

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The fixation of an artificial intervertebral disc has been studied especially with respect to the dimensions, the convexity of the endplates and the size of the fixation elements. From literature and cadaveric vertebrae, the dimensions and shape of the lumbar vertebral endplates were determined and the dimensions of fixation ribs for the artificial intervertebral disc were calculated. To withstand shear forces and prevent dislocation, two sagittal ribs, each 3.5 mm in height and at least 20 mm in length and four transversal ribs, each 1.5 mm in height and with a total length of 60 mm are suffi
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Harada, Takashi, and Podi Liu. "Internal and External Forces Measurement of Planar 3-DOF Redundantly Actuated Parallel Mechanism by Axial Force Sensors." ISRN Robotics 2013 (October 9, 2013): 1–8. http://dx.doi.org/10.5402/2013/593606.

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This paper proposes a method for measuring the internal and external forces of a planar 3-DOF (degree of freedom) redundantly actuated parallel mechanism. The internal forces, force acts inside the endplate and mechanism constraint force, and the external forces, forces act on the endplate and thrusts by actuators, were measured simultaneously using the axial forces of the rods. Kinetostatic equations of the parallel mechanism were used to derive algorithms for measuring the internal and external forces. A link axis force sensor was developed using a strain gauge sensor. To verify the actual i
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Kotowski, S. E., K. G. Davis, R. J. Parkinson, and J. P. Callaghan. "Taking an Acceleration Approach to Identifying Vertebral Endplate Failures." Proceedings of the Human Factors and Ergonomics Society Annual Meeting 51, no. 15 (October 2007): 938–42. http://dx.doi.org/10.1177/154193120705101515.

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Identification of spine tolerances has typically involved the complete destruction of functional spinal units in order to confirm an endplate fracture. A new method of identifying endplate fractures utilizing the measurement of acceleration response through accelerometers mounted to the functional spinal unit was tested on porcine spines. Functional spinal units were mechanically tested to failure using a cyclic loading protocol modeled after the expected loading during a lifting task. Over 80% of the segments had visible endplate fractures upon dissection. Trends in acceleration profiles reve
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Burges, Judith, Dennis W. Wray, Sergio Pizzighella, Zach Hall, and Angela Vincent. "A myasthenia gravis plasma immunoglobulin reduces miniature endplate potentials at human endplates in vitro." Muscle & Nerve 13, no. 5 (May 1990): 407–13. http://dx.doi.org/10.1002/mus.880130507.

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Ruff, R. L., and D. Whittlesey. "Comparison of Na+ currents from type IIa and IIb human intercostal muscle fibers." American Journal of Physiology-Cell Physiology 265, no. 1 (July 1, 1993): C171—C177. http://dx.doi.org/10.1152/ajpcell.1993.265.1.c171.

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The voltage dependence and amplitude of Na+ currents (INa) were studied with the loose-patch voltage-clamp technique on 19 fast-twitch human intercostal skeletal muscle fibers at the endplate border and > 200 microns from the endplate (extrajunctional). The fibers were histochemically classified as fast-twitch oxidative-glycolytic (type IIa, n = 9) or fast-twitch glycolytic (type IIb, n = 10). The voltage dependence of activation and fast and slow inactivation of INa were similar for membrane patches recorded on the endplate border and on extrajunctional membrane for both fiber types. INa w
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Haastert, Kirsten, Maria Grosheva, Srebrina K. Angelova, Orlando Guntinas-Lichius, Emmanouil Skouras, Joern Michael, Claudia Grothe, Sarah A. Dunlop, and Doychin N. Angelov. "Schwann Cells Overexpressing FGF-2 Alone or Combined with Manual Stimulation Do Not Promote Functional Recovery after Facial Nerve Injury." Journal of Biomedicine and Biotechnology 2009 (2009): 1–11. http://dx.doi.org/10.1155/2009/408794.

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Purpose. To determine whether transplantation of Schwann cells (SCs) overexpressing different isoforms of fibroblast growth factor 2 (FGF-2) combined with manual stimulation (MS) of vibrissal muscles improves recovery after facial nerve transection in adult rat.Procedures. Transected facial nerves were entubulated with collagen alone or collagen plus naïve SCs or transfected SCs. Half of the rats received daily MS. Collateral branching was quantified from motoneuron counts after retrograde labeling from 3 facial nerve branches. Quality assessment of endplate reinnervation was combined with vid
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