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Dissertations / Theses on the topic 'Energy expenditure'

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1

Riou, Marie-Ève. "Energy Compensation Following Exercise-Induced Energy Expenditure." Thesis, Université d'Ottawa / University of Ottawa, 2014. http://hdl.handle.net/10393/31292.

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This thesis aims to determine energy compensation following exercise induced energy expenditure (ExEE). The specific objectives were: I) to determine the impact of the time spent performing physical activity (PA) of varying intensities on body weight and composition (Study 1); II) to determine the overall energy compensation and the major predictors of energy compensation through the systematic review approach (Study 2); III) to develop new methods to measure energy intake (EI) (Study 3) and time spent performing different activities (Study 4); IV) to determine the effects of a lower (LI) and
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Davies, Peter S. W. "Total energy expenditure in infancy." Thesis, Loughborough University, 1991. https://dspace.lboro.ac.uk/2134/32808.

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This thesis is concerned primarily with the measurement of total energy expenditure in infancy. Until the advent and subsequent development of the doubly labelled water technique for the assessment of carbon dioxide production rate in "free-living" individuals measurements of total energy expenditure in infants and children were virtually impossible. Thus measurements of total energy expenditure using this relatively new technique are of burgeoning interest to nutritionists, clinicians and human biologists.
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3

Black, Alison E. "Dietary energy intake measurements : validations against energy expenditure." Thesis, University of Ulster, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.322419.

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4

Croft, Louise. "Investigating energy expenditure in wheelchair athletes." Thesis, Loughborough University, 2012. https://dspace.lboro.ac.uk/2134/9788.

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The increased participation in elite wheelchair sport has provided the need to investigate the physiological requirements of wheelchair sporting competition and daily wheelchair propulsion. However, from a nutritional perspective, guidelines that have been established from the able-bodied population tend to be used by the practitioners working in disability sport and it is not known whether this information is directly transferable to the wheelchair athlete. Wheelchair sport is complex and athletes differ with respect to their sports classification based on factors relating to disability and f
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5

Reiches, Meredith Wayden. "Female Adolescent Energy Expenditure in the Gambia." Thesis, Harvard University, 2012. http://dissertations.umi.com/gsas.harvard:10031.

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Adolescence is a life history transition of individual and evolutionary importance: the body begins to allocate energy available above maintenance costs away from somatic growth and towards reproductive function. This study investigates how both distal, intergenerational effects and proximal, seasonal changes in energy availability impact the way adolescent female bodies allocate energy among linear growth, fat and lean mass, activity, and metabolic function. The research follows up on a prenatal supplementation study conducted by the British Medical Research Council in rural Gambia between 19
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Brown, Joshua T. "The Energy Expenditure of Heavy Metal Drummers." TopSCHOLAR®, 2016. http://digitalcommons.wku.edu/theses/1647.

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The purpose of this investigation is to examine the energy demand of heavy metal drummers during rehearsal in order to understand the physiological responses. This information may lead to a better understanding of energy expenditure and add to the compendium of physical activity. The investigation consisted of eight apparently healthy 20 to 37-year-old males were recruited for this investigation. Information gathered during the drum test was average VO2, VO2peak, HR in beats per minute (bpm), metabolic equivalents (METs), and energy expenditure (EE) expressed in calories (kcals) per minute and
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Meyer, Rosan Waldtraut. "Energy expenditure in the critically ill child." Thesis, Imperial College London, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.498431.

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8

Kreshel, Leigh Anne. "Increasing energy expenditure of cardiac rehabilitation patients." Electronic thesis, 2002. http://dspace.zsr.wfu.edu/jspui/handle/10339/175.

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9

Bross, Rachelle. "Fluoxetine and energy expenditure in obese humans subjected to energy restriction." Thesis, McGill University, 1993. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=69699.

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I investigated the effects of continuous administration of fluoxetine, a serotonin reuptake inhibitor, on energy expenditure, body temperature, and thyroid and catecholamine metabolism during weight reduction using a very low calorie diet (VLCD, Optifast, 1757 kJ/day) followed by a balanced deficit diet (BDD, 5016 kJ/day). Fluoxetine (60 mg/day by mouth, n = 10) or placebo (n = 10) were administered during 3 weeks of inpatient VLCD followed by 8 weeks of outpatient BDD in a double-blind, randomized design. A similar amount of weight was lost in both groups during the VLCD, but by the end of th
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10

Kirkwood, Demetrice. "The Effects of Playing Exergames on Energy Expenditure." TopSCHOLAR®, 2011. http://digitalcommons.wku.edu/theses/1133.

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The purpose of this study was to assess the performance, ratings of perceived exertion, metabolic responses, and energy expenditure as individuals participated in interactive video game play. There were 14 participants that participated in the study, whose age was 20.1 ± 1.64 years of age. Participants completed a maximal aerobic test to exhaustion (VO2max test), and then 30 minute testing session on both the Kinect Adventures (K) and Wii Fit Plus game. Data were analyzed using a dependent t-test and one-way ANOVA. Significance was accepted at P ≤ 0.05. Energy expenditure and RPE were signific
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11

Sridharan, Sivakumar. "Energy expenditure in kidney failure : implications for management." Thesis, University of Hertfordshire, 2014. http://hdl.handle.net/2299/14932.

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Renal replacement therapy, in the form of dialysis or transplantation, is the cornerstone of management for end-stage renal disease. UK renal registry shows nearly half of those needing renal replacement therapy are treated by dialysis – predominantly by haemodialysis. Patients on renal replacement therapy have increased mortality risk compared to age matched general population. Moreover, some specific subgroups of patients on haemodialysis have increased risk of mortality than expected. The survival benefit seen in women in the general population is attenuated resulting in similar survival fo
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12

Wilhelm, Spencer Christian. "Prediction of Non-Resting Energy Expenditure using Accelerometry." Thesis, Virginia Tech, 2019. http://hdl.handle.net/10919/91463.

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The accurate measurement of total energy expenditure is a cornerstone of metabolic research. However, there is a lack of measurement methods that are valid, objective, inexpensive, and easy to use. Accelerometry, along with validated prediction equations for resting energy requirements, may provide an opportunity to fill this void. Twenty weight stable adults (12 female, 8 male) who recently participated in a controlled feeding study comprised the study sample. Total energy requirements were assessed from the controlled feeding period in which weight stability was achieved using the intake
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13

Hartman, Michael(Michael J. ). S. B. Massachusetts Institute of Technology. "Analysis of MIT's past and future energy expenditure/." Thesis, Massachusetts Institute of Technology, 2019. https://hdl.handle.net/1721.1/123295.

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Thesis: S.B., Massachusetts Institute of Technology, Department of Mechanical Engineering, 2019<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (page 24).<br>With the current rate at which technology is advancing, MIT has to update and replace out-of-date facilities as well as add new ones to stay at the forefront of university research. As MIT continues to expand its facilities, the amount of energy required to run those facilities will also increase. An analysis of future energy usage allows for energy saving systems to be planned before the facilities are com
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14

Silalertdetkul, Supaporn. "Effect of acute exercise on energy intake, physical activity energy expenditure and energy balance hormones in sedentary and active men." Thesis, University of Bath, 2009. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.520328.

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An exercise-induced energy deficit may affect post-exercise energy intake, physical activity energy expenditure (PAEE) and energy balance hormones. Therefore, the objective of this thesis was to investigate the impact of a single bout of exercise either of moderate (40% O2max) or high (70% O2max) intensity on post-exercise energy intake, physical activity energy expenditure and energy balance hormones in both sedentary and active males. Physical activity energy expenditure increased between 38 and 62 hours following moderate intensity exercise in sedentary males (Chapters 3 and 4). This was du
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15

Ekelund, Ulf. "Assessment of physical activity and energy expenditure in adolescents /." Stockholm, 2002. http://diss.kib.ki.se/2002/91-7349-186-1.

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Pulfrey, Simon M. "Energy expenditure and requirement while climbing at extreme altitude." Thesis, McGill University, 1995. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=23288.

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Humans can only survive the low barometric pressure of altitudes above 6000m by making a complex series of adaptations. The energetics of human survival at such extreme altitudes have not been widely studied. Objectives were to compare the doubly labelled water (DLW) and intake-balance (IB) methods to estimate daily energy expenditure while climbing between 6000 and 8046m and to investigate the putative metabolic cost involved with the process of acclimatization to extreme altitude. Reliability of the DLW method to provide an accurate and portable means to measure human energy expenditure depe
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Ramírez-Marrero, Farah A. "Physical activity and energy expenditure in African-American children /." The Ohio State University, 1997. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487948440827395.

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18

Miwa, Masafumi. "Estimation of energy expenditure of grazing ruminants via accelerometry." 京都大学 (Kyoto University), 2017. http://hdl.handle.net/2433/225658.

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Kyoto University (京都大学)<br>0048<br>新制・課程博士<br>博士(農学)<br>甲第20433号<br>農博第2218号<br>新制||農||1048(附属図書館)<br>学位論文||H29||N5054(農学部図書室)<br>京都大学大学院農学研究科応用生物科学専攻<br>(主査)教授 廣岡 博之, 教授 久米 新一, 教授 今井 裕<br>学位規則第4条第1項該当
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19

Ikeda, Kaori. "Estimation of basal energy expenditure in patients with diabetes." Kyoto University, 2013. http://hdl.handle.net/2433/174813.

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20

Hongu, Nobuko, Jamie M. Wise, Barron J. Orr, and Kristin D. Wisneski. "GPS Watches for Measuring Energy Expenditure during Physical Activity." College of Agriculture, University of Arizona (Tucson, AZ), 2014. http://hdl.handle.net/10150/324540.

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Revised; Originally published: 10/2008<br>3 pp.<br>Recently, a number of global positioning system (GPS) devices have been introduced commercially which exploit GPS, transforming frequent measurements of time and location, into an estimate of energy expenditure. This fact sheet reviews how GPS watches (GPS fitness units) measure energy expenditure of individual during physical activity. We list popular GPS watches that are on the market and show pros and cons of these watches. After our field testing, we decided that the Garmin Forerunner 305 is our best pick for the GPS watch. We included inf
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Hongu, Nobuko, Jamie M. Wise, Barron J. Orr, and Kristin D. Wisneski. "GPS Watches for Measuring Energy Expenditure during Physical Activity." College of Agriculture and Life Sciences, University of Arizona (Tucson, AZ), 2008. http://hdl.handle.net/10150/146669.

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4 pp.<br>Recently, a number of global positioning system (GPS) devices have been introduced commercially which exploit GPS, transforming frequent measurements of time and location, into an estimate of energy expenditure. This fact sheet reviews how GPS watches (GPS fitness units) measure energy expenditure of individual during physical activity. We list popular GPS watches that are on the market and showed pros and cons of these watches. After our field testing, we decided that Garmin Forenunner 305 is our best pick for the GPS watch. We included information on Geocashing, which is one of popu
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22

Sharpe, Jenny-Kay. "Body composition and energy expenditure in men with schizophrenia." Thesis, Queensland University of Technology, 2007. https://eprints.qut.edu.au/16961/1/Jenny-Kay_Sharpe_Thesis.pdf.

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There is an increase in the prevalence of obesity among people with schizophrenia thought to be due in part to the weight enhancing side-effects of medications commonly used to treat the symptoms of schizophrenia. Despite the deleterious health effects associated with obesity and its impact on quality of life and medication compliance, little is known about body composition and energy expenditure in this clinical group. The primary purpose of this thesis was to enhance understanding of body composition and energy expenditure, particularly resting energy expenditure in men with schizophrenia wh
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23

Sharpe, Jenny-Kay. "Body composition and energy expenditure in men with schizophrenia." Queensland University of Technology, 2007. http://eprints.qut.edu.au/16961/.

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There is an increase in the prevalence of obesity among people with schizophrenia thought to be due in part to the weight enhancing side-effects of medications commonly used to treat the symptoms of schizophrenia. Despite the deleterious health effects associated with obesity and its impact on quality of life and medication compliance, little is known about body composition and energy expenditure in this clinical group. The primary purpose of this thesis was to enhance understanding of body composition and energy expenditure, particularly resting energy expenditure in men with schizophrenia wh
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24

Stoltz, Victor, and Manne Godhe. "Validity of accelerometry in high-intensity complex movements." Thesis, Gymnastik- och idrottshögskolan, GIH, Institutionen för idrotts- och hälsovetenskap, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:gih:diva-3268.

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Abstract Aim The aim of the study was to examine the capability of accelerometers to estimate energy expenditure during high-intensity complex physical activity patterns. Also, to investigate whether placing the monitor on the hip or wrist influenced its prediction ability. Furthermore, the purpose was also to evaluate if there was a significant difference in the aforementioned estimations using data from one axis compared to all three axis combined.     Method A total of 14 subjects, eight men and six women, mean (SD) age of 26, 4 (5,5) years were recruited for the study. The participants pe
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25

Hambly, Catherine. "Cost of flight in small birds using the '1'3C labelled bicarbonate technique." Thesis, University of Aberdeen, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.369631.

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26

Rocha, Joel Borges Pinto Ferreira da. "Effects of exercise on hunger, food intake and energy expenditure." Thesis, Sheffield Hallam University, 2013. http://shura.shu.ac.uk/17906/.

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Research in this thesis has examined the acute and chronic effects of exercise on hunger, energy intake and expenditure. Cross-sectional studies examined the effect of 60 min of moderate-intensity cycling on immediate and subsequent three day energy intake and expenditure in active and inactive men (study one) and women not using hormonal contraceptives (study two) and taking oral contraceptives (study three). Study four examined the effects of 12 weeks of moderate-intensity aerobic exercise on 7-day free-living energy intake and expenditure. A total of 47 men (mean ± SD; age 23.8 ± 4.2 y; bod
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Bross, Rachelle. "Tyrosine requirements and resting energy expenditure in patients with phenylketonuria." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp02/NQ27610.pdf.

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28

Staal-van, den Brekel Agnes Josefien. "The inflammatory response and resting energy expenditure in lung cancer." [Maastricht : Maastricht : Universiteit Maastricht] ; University Library, Maastricht University [Host], 1996. http://arno.unimaas.nl/show.cgi?fid=6707.

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29

Yenter, Jaclyn. "Energy expenditure during chewing: a comparison of two measurement methods." Thesis, Wichita State University, 2011. http://hdl.handle.net/10057/3994.

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Older adults with chewing and swallowing difficulties frequently report increased fatigue and effort, or energy expenditure, during eating. Energy is defined as the ability to perform work. It is most accurately measured through an examination of the gaseous composition of inhaled and exhaled air at rest and during activity using laboratory-based indirect calorimetry. There is a need for a valid measure of energy expenditure that can be used to document the effort involved in eating and swallowing in natural contexts. The purpose of the current study was to determine the concurrent validity of
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Dalton, Alexander Jonathan MacGregor. "Daily energy expenditure of northern fur seals : techniques and measurements." Thesis, University of British Columbia, 2014. http://hdl.handle.net/2429/46004.

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Seasonal changes in the daily energy expenditure (DEE) of captive northern fur seals (Callorhinus ursinus) and key components of their energy budget (cost of resting metabolism, thermoregulation, activity and growth) were examined to elucidate potential reasons for the species’ population decline in the wild. The average DEE of 6 females was 527.8 ± 65.7 kJ kg-¹ d-¹ and fluctuated seasonally (~20% greater in the fall than in the winter). Resting metabolism also changed significantly with season, and was higher in the fall (potentially due to molting or as preparation for migratory activity). W
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Bellinger, Leanne. "Nutritional programming of feeding behaviour, energy expenditure and body fatness." Thesis, University of Nottingham, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.428940.

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Stiegler, P. "Energy expenditure following different combinations of exercise and macronutrient intake." Thesis, University of Westminster, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.441076.

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33

Horner, Fleur. "Use of accelerometry to predict energy expenditure in military tasks." Thesis, University of Bath, 2012. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.558908.

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The overarching aim of this thesis was to enhance the prediction of physical activity energy expenditure (PAEE) in military personnel; specifically, improving accuracy and minimising obtrusiveness. The first experimental chapter provided a thorough assessment of the reliability and validity of the 3DNX accelerometer. Within unit reliability (CVintra) physical activity counts (PAC) was 0.0-8.9% in all axes in a mechanical setting. Between unit reliability (CVinter) did not exceed 4.5%.The relationship between PAC and acceleration was r2 = 0.99 and standard error of the estimate (SEE) of 6 count
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Waite, Violet S. K. "A study of influencing factors on energy expenditure and intake." Thesis, Oxford Brookes University, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.407368.

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The subject of energy balance in humans has been well researched over the past one hundred years. However, the reason why some individuals are better at regulating their body weight than others is still far from clear. The aim of this study was to further investigate the relationship between energy expenditure and energy intake under varying conditions. The first phase involved a set of three experiments. Experiment 1 (n=15, men) was based on expending energy through exercise (EX)(837 kJ on a cycle-ergometer), exercise in the cold (11-13°C) (CES), exercise with prior caffeine (200mg) ingestion
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Dijkman, Johannes T. "The measurement of draught ruminant energy expenditure in the field." Thesis, University of Edinburgh, 1994. http://hdl.handle.net/1842/29731.

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The aim of this work was improve and validate the Oxylog portable oxygen consumption meter for use with draught ruminants, and to test its ability to estimate the energy expenditure of these animals in the field. Few data were available on the energy costs of the various tasks that draught ruminants perform and it was expected that the calorific factors established during laboratory experiments may not necessarily reflect the energy consumption during field work with farmers. This could have important implications in the establishment of the nutritional requirements of draught ruminants. A rev
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Braddick, Jeanne Ann. "Energy intake and expenditure in individual female collegiate distance runners." Thesis, Virginia Tech, 1986. http://hdl.handle.net/10919/41556.

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<p>In recent studies, caloric intakes among female distance runners were reported to be insufficient to support training intensities. To study energy intake and expenditure in female collegiate distance runners, ten members of the Virginia Tech cross-country team were utilized as subjects.</p><br>Master of Science
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Harper, Jane. "Improving Estimation of Resting Energy Expenditure in Seriously Injured Individuals." University of Cincinnati / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1241571769.

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Bachir, Kelsey Nawal. "Energy expenditure in rats bred for response to exercise training." Kent State University Honors College / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=ksuhonors1376672737.

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Raje, Vidisha. "Role of Tyk2 in regulating energy expenditure and preventing obesity." VCU Scholars Compass, 2013. http://scholarscompass.vcu.edu/etd/3184.

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Obesity develops when energy intake exceeds energy expenditure. Defect in the function of brown fat and skeletal muscle, two of the major tissues that contribute towards energy expenditure, lead to the development of obesity and metabolic syndrome. Our previous findings suggest that Tyk2 deficient mice become obese and develop the metabolic syndrome. Tyk2, which is a tyrosine kinase of the JAK-STAT signaling family, is important for optimal brown development and function. Since brown fat and skeletal muscle, both are derived from the Myf5+ lineage of mesenchymal stem cells, we also characteriz
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McClune, David William. "Energy expenditure and behaviour of the European badger (Meles meles)." Thesis, Queen's University Belfast, 2016. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.707834.

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This thesis begins by examining the factors that affect metabolic rate, before turning to the measurement of energy expenditure and the quantification of behaviour in the European badger (Meles meles). Resting metabolic rate and daily energy expenditure (DEE) were measured (by respirometry and doubly labelled water, respectively) in a population of free-ranging badgers and analysed in terms of age, sex, season, and bovine tuberculosis (bTB) disease status. In a pilot study with a captive tame badger, a tri-axial accelerometer equipped collar was used to gather data on badger movement. Custom s
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Mackenzie, Kelly. "Energy intake, resting energy expenditure, activity levels, energy balance and serum hormone concentrations in sedentary and athletic males." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape3/PQDD_0013/MQ60150.pdf.

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Voon, Rudi Electrical Engineering &amp Telecommunications Faculty of Engineering UNSW. "A telemedicine-based energy monitor for managing diabetes mellitus." Publisher:University of New South Wales. Electrical Engineering & Telecommunications, 2008. http://handle.unsw.edu.au/1959.4/41328.

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Diabetes mellitus is a chronic disease in which the body does not produce sufficient insulin or in which the body has high insulin resistance thus making the regulation of blood glucose metabolism difficult. Currently, diabetes is still incurable. All patients need to well manage their blood glucose levels to reduce the risk of complications. This dissertation is comprised of two major studies. In diabetes type I, the blood glucose can only be managed by multiple daily injection of insulin. However, most patients tend to have difficulty in deciding the right amount of insulin dose. The first
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Matthews, Deborah S. F. "The whole body stress response to severe childhood head injury and its relationship to cerebral metabolism." Thesis, University of Newcastle Upon Tyne, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.294870.

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Kumar, Karthik. "Energy expenditure analysis of redesigned mechanical assists for medium girder bridge." Diss., Rolla, Mo. : Missouri University of Science and Technology, 2010. http://scholarsmine.mst.edu/thesis/pdf/Kumar_09007dcc807c4bad.pdf.

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Thesis (M.S.)--Missouri University of Science and Technology, 2010.<br>Vita. The entire thesis text is included in file. Title from title screen of thesis/dissertation PDF file (viewed June 29, 2010) Includes bibliographical references (p. 77-78).
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Schwartz, Alexander. "Examining the Effects of Weight Loss on Energy Expenditure in Humans." Thesis, Université d'Ottawa / University of Ottawa, 2011. http://hdl.handle.net/10393/20455.

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Being able to effectively match energy intake to energy expenditure (EE) is an important aspect in preventing weight re-gain in the post-obese. Although it is generally agreed upon that resting EE decreases concomitantly with weight loss, there is no set standard comparing the deviations with differing weight loss protocols and additionally, controversy remains as to whether this decrease is greater than can predicted. In order to address these issues 2977 subjects were analyzed using a systematic review and the differences of both the protocol and length of various interventions in addition t
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Melnyk, Anna. "Brown adipose tissue atrophy, effects on energy expenditure and body composition." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp02/NQ28359.pdf.

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Chang, Miriam M. Y. "Longitudinal changes in energy expenditure and body composition of preterm infants." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ33216.pdf.

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Baarends, Erica Maria. "Effort related energy expenditure in patients with chronic obstructive pulmonary disease." Maastricht : Maastricht : Universiteit Maastricht ; University Library, Maastricht University [Host], 1997. http://arno.unimaas.nl/show.cgi?fid=5924.

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McKenzie, James Michael. "The use of GPS to predict energy expenditure for outdoor walking." Thesis, Montana State University, 2007. http://etd.lib.montana.edu/etd/2007/mckenzie/McKenzieJ0507.pdf.

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Djafarian, K. "Association between energy expenditure and body composition in pre-school children." Thesis, University of Aberdeen, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.590985.

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The aim of my thesis was to assess the variability of EE and weight up the link between this variability and body composition in pre-school children (89 subjects). A further aim was to validate a wrist worn acelerometry (Actiwatch) against direct observation and compare two-points and multi-points calculation methods of total EE using DLW. Our results indicated that Actiwatch is valid and reliable for assessing physical activity (PA) pattern in children. In second study we observed that there was no significant difference between two sample points and multiple sample points to calculate total
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