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Journal articles on the topic 'Enilconazole'

Author: Grafiati

Published: 4 June 2021

Last updated: 9 February 2022

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1

Moriello, Karen A. "Kennel Disinfectants forMicrosporum canisandTrichophytonsp." Veterinary Medicine International 2015 (2015): 1–3. http://dx.doi.org/10.1155/2015/853937.

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The antifungal efficacy of commonly used kennel disinfectants for large surfaces was tested using naturally infective material from untreated animals (M. canisandTrichophytonsp.) soaked and macerated but unfiltered leaving visible fluorescing hairs and/or scales in the test inoculum to create a robust challenge. Disinfectants included sodium hypochlorite (1 : 32 and 1 : 100), enilconazole (1 : 100), accelerated hydrogen peroxide (1 : 16), potassium peroxymonosulfate (1% and 2%), and calcium hypochlorite “dry bleach.” Disinfectants were tested at a 1 : 10, 1 : 5, and 1 : 1 dilution of test inoculum to disinfectant with a 10 min contact time. Good efficacy was defined as a disinfectant resulting in no growth. Control plates grew >300 colonies of each pathogen per plate. Enilconazole, sodium hypochlorite (all dilutions), accelerated hydrogen peroxide, and 2% potassium peroxymonosulfate (but not 1%) inhibited all growth of both pathogens at 1 : 10, 1 : 5, and 1 : 1 dilutions. Calcium hypochlorite showed no antifungal efficacy (>300 colonies per plate). Enilconazole (1 : 100), sodium hypochlorite (1 : 32 or 1 : 100), accelerated hydrogen peroxide (1 : 16), and 2% potassium peroxymonosulfate are recommended for decontamination of kennels exposed to dermatophyte pathogens.

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2

Cutsem, J., F. Gerven, H. Geerts, and F. Rochette. "Treatment with Enilconazole* Spray of Dermatophytosis in Rabbit Farms: Behandlung von Dermatophytosen mit Enilconazol* Spray in Kaninchenbetrieben." Mycoses 28, no. 8 (April 24, 2009): 400–407. http://dx.doi.org/10.1111/j.1439-0507.1985.tb02151.x.

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3

White-Weithers, N., and L. Medleau. "Evaluation of topical therapies for the treatment of dermatophyte-infected hairs from dogs and cats." Journal of the American Animal Hospital Association 31, no. 3 (May 1, 1995): 250–53. http://dx.doi.org/10.5326/15473317-31-3-250.

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Seven commonly used, topical antifungal products (i.e., lime sulfur, chlorhexidine, captan, povidone-iodine, sodium hypochlorite, and enilconazole solutions, and ketoconazole shampoo) were evaluated for their antifungal activity on Microsporum canis-infected hairs from dogs and cats in an in vitro study. Hairs were soaked or shampooed in each product for five minutes twice a week for four weeks. Of the seven products used in this study, lime sulfur and enilconazole solutions were superior in inhibiting fungal growth; no growth occurred on fungal cultures after two treatments with either product. Chlorhexidine and povidone iodine solutions were effective after four treatments, and sodium hypochlorite solution and ketoconazole shampoo inhibited fungal growth after eight treatments. Captan did not inhibit fungal growth during the test period.

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4

Kendall, A., J. Bröjer, E. Karlstam, and J. Pringle. "Enilconazole Treatment of Horses with SuperficialAspergillusSpp. Rhinitis." Journal of Veterinary Internal Medicine 22, no. 5 (September 2008): 1239–42. http://dx.doi.org/10.1111/j.1939-1676.2008.0173.x.

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5

Sharp, Nicholas J. H., Martin Sullivan, Colin E. Harvey, and Tony Webb. "Treatment of Canine Nasal Aspergillosis with Enilconazole." Journal of Veterinary Internal Medicine 7, no. 1 (January 1993): 40–43. http://dx.doi.org/10.1111/j.1939-1676.1993.tb03167.x.

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6

Zonderland, Jean-Luc, Christoph K. Störk, Jimmy H. Saunders, Annick J. Hamaide, Marc H. Balligand, and Cecile M. Clercx. "Intranasal infusion of enilconazole for treatment of sinonasal aspergillosis in dogs." Journal of the American Veterinary Medical Association 221, no. 10 (November 2002): 1421–25. http://dx.doi.org/10.2460/javma.2002.221.1421.

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7

Sharp, N., and M. Sullivan. "Treatment of canine nasal aspergillosis with systemic ketoconazole and topical enilconazole." Veterinary Record 118, no. 20 (May 17, 1986): 560–61. http://dx.doi.org/10.1136/vr.118.20.560.

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8

Boyen, F., P. Van Rooij, L. Vanstallen, B. Flahou, and F. Haesebrouck. "Microsporum gypseum infection in a horse with severe sweet itch." Vlaams Diergeneeskundig Tijdschrift 87, no. 3 (June 28, 2018): 139–42. http://dx.doi.org/10.21825/vdt.v87i3.16077.

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In a horse with severe sweet itch and a history of corticosteroid treatment for this disorder, a single, well-circumscribed and crusty white lesion was present on the thigh. The geophilic dermatophyte species M. gypseum was cultured from the lesion. The lesion was treated topically once a week with an enilconazole emulsion for four weeks. Full recovery was noted after two months. This case suggests that sweet itch combined with systemic corticosteroid treatment, may act as predisposing factor for dermatophyte infection. In addition, the importance of correct isolation and identification of the causal agent is highlighted.

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9

Schuller, Simone, and Cecile Clercx. "Long-Term Outcomes in Dogs With Sinonasal Aspergillosis Treated With Intranasal Infusions of Enilconazole." Journal of the American Animal Hospital Association 43, no. 1 (January 1, 2007): 33–38. http://dx.doi.org/10.5326/0430033.

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Long-term outcomes (mean 38±17 months) were evaluated in 27 dogs with sinonasal aspergillosis after successful medical treatment using intranasal infusions of 1% or 2% enilconazole (1%, n=15; 2%, n=12). Long-term outcomes with both treatment protocols were good, with half of the dogs being asymptomatic throughout the follow-up period. The remaining dogs showed mild clinical signs compatible with chronic rhinitis/sinusitis. These clinical signs were interpreted as chronic lymphoplasmacytic rhinitis/sinusitis and episodes of bacterial rather than fungal infection. Three dogs had confirmed reinfection or relapse 2 to 36 months after clinical resolution.

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10

Moriello, Karen A. "In vitro efficacy of shampoos containing miconazole, ketoconazole, climbazole or accelerated hydrogen peroxide against Microsporum canis and Trichophyton species." Journal of Feline Medicine and Surgery 19, no. 4 (July 9, 2016): 370–74. http://dx.doi.org/10.1177/1098612x15626197.

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Objectives The objective was to evaluate the antifungal efficacy of shampoo formulations of ketoconazole, miconazole or climbazole and accelerated hydrogen peroxide wash/rinse against Microsporum canis and Trichophyton species spores. Methods Lime sulfur (1:16)-treated control, enilconazole (1:100)-treated control, accelerated hydrogen peroxide (AHP 7%) 1:20 and a 1:10 dilution of shampoo formulations of miconazole 2%, miconazole 2%/chlorhexidine gluconate 2–2.3%, ketoconazole 1%/chlorhexidine 2%, climbazole 0.5%/chlorhexidine 3% and sterile water-untreated control were tested in three experiments. In the first, a suspension of infective spores and hair/scale fragments was incubated with a 1:10, 1:5 and 1:1 dilution of spores to test solutions for 10 mins. In the second, toothbrushes containing infected cat hair in the bristles were soaked and agitated in test solutions for 10 mins, rinsed, dried and then fungal cultured (n = 12×). In the third, a 3 min contact time combined with an AHP rinse was tested (n = 10×). Good efficacy was defined as no growth. Results Water controls grew >300 colony-forming units/plate and all toothbrushes were culture-positive prior to testing. For the suspension tests, all test products showed good efficacy. Miconazole 2%, ketoconazole 1% and AHP showed good efficacy after a 10 min contact time. Good efficacy was achieved with a shorter contact time (3 mins) only if combined with an AHP rinse. Conclusions and relevance Lime sulfur and enilconazole continued to show good efficacy. In countries or situations where these products cannot be used, shampoos containing ketoconazole, miconazole or climbazole are alternative haircoat disinfectants, with a 10 min contact time or 3 mins if combined with an AHP rinse.

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11

Iacob, Olimpia, and Adriana Iftinca. "The dermatitis by Caparinia tripilis and Microsporum , in african pygmy hedgehog (Atelerix albiventris) in Romania – first report." Revista Brasileira de Parasitologia Veterinária 27, no. 4 (August 30, 2018): 584–88. http://dx.doi.org/10.1590/s1984-296120180053.

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Abstract Investigations were conducted on a case of generalized dermatitis in an African pygmy hedgehog (Atelerix albiventris), purchased as a pet. Clinical examination revealed restlessness, agitation, itching and scratching, large alopecic areas, skin congestion and thin whitish scabs. Five skin lesions were scraped and the samples were collected for laboratory tests. Microscopy revealed the presence of the mite Caparinia tripilis (Acari: Psoroptidae). A dermatophyte belonging to Microsporum genus was also isolated by culture on specific media. Selamectin spot-on and enilconazole washes were used for treatment, resulting in skin healing and spines growing. To our knowledge, this is the first reported case of Caparinia tripilis dermatitis in a hedgehog in Romania.

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12

Knotkova, Z., S. Mazanek, M. Hovorka, M. Sloboda, and Z. Knotek. "Haematology and plasma chemistry of Bornean river turtles suffering from shell necrosis and haemogregarine parasites ." Veterinární Medicína 50, No. 9 (March 28, 2012): 421–26. http://dx.doi.org/10.17221/5643-vetmed.

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Nine Bornean river turtles (Orlitia borneensis, Gray, 1873) suffering from lethargy, ulcerations and caseous necrosis of the plastron were evaluated for haematology and plasma chemistry. Intra-erythrocytic haemogregarine parasites were associated with anaemia, low haemoglobin, basophilia, eosinophilia, heterophilia and azurophilia. After eight months of treatment consisting of antibiotics, debridement and scrubbing of lesions with enilconazole or povidone iodine, rehydration, deworming and tube feeding, lymphocytes, basophils, eosinophils, heterophils and azurophils returned to the normal ranges. Haematocrit, RBC and haemoglobin concentration were under the normal ranges in 24 months. A progressive decrease in haemogregarine parasitaemia was also seen, however, haematologic changes could not be definitely attributed to these parasites.

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13

Dengler, Berrett, Christoph Klinger, Sonya Bettenay, Volker Rickerts, Ralf Mueller, and Janine Classen. "Cutaneous alternariosis in an immunocompromised dog successfully treated with cold plasma and cessation of immunosuppressive medication." Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere 45, no. 05 (2017): 337–43. http://dx.doi.org/10.15654/tpk-160851.

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SummaryA cutaneous infection with Alternaria spp. was diagnosed in a 2-yearold male intact Irish setter dog, presenting with multifocal papules, plaques and ulcerations involving all four distal limbs, shoulder blades, scrotum, pinnae and nasal mucous membranes. The dog had been treated for inflammatory bowel disease and lymphangiectasia with immunosuppressive doses of cyclosporine and prednisolone for approximately 3 months. The diagnosis was based on clinical signs, the demonstration of fungal elements within skin biopsies, deep fungal culture and fungal PCR from a formalin-fixed tissue specimen. Complete clinical remission was achieved by tapering and cessation of the immunosuppressive medication, treatment with cold atmospheric-pressure plasma (CAPP) and topical enilconazole within 8 weeks.

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14

Davis, E. W., and A. M. Legendre. "Successful Treatment of Guttural Pouch Mycosis With Itraconazole and Topical Enilconazole in a Horse." Journal of Veterinary Internal Medicine 8, no. 4 (July 1994): 304–5. http://dx.doi.org/10.1111/j.1939-1676.1994.tb03239.x.

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15

Hnilica, Keith A., and Linda Medleau. "Evaluation of topically applied enilconazole for the treatment of dermatophytosis in a Persian cattery." Veterinary Dermatology 13, no. 1 (February 2002): 23–28. http://dx.doi.org/10.1046/j.0959-4493.2001.00282.x.

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16

Bray, J. P., R. A. S. White, and B. D. X. Lascelles. "Treatment of canine nasal aspergillosis with a new non-invasive technique. Failure with enilconazole." Journal of Small Animal Practice 39, no. 5 (May 1998): 223–26. http://dx.doi.org/10.1111/j.1748-5827.1998.tb03638.x.

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17

Kirmizigul, Ali Haydar, Ekin Emre Erkilic, Fatih Buyuk, Erhan Gokce, and Mehmet Citil. "Efficacy of pomades containing different percentages of enilconazole in the treatment of bovine dermatophytosis." Veterinary Dermatology 27, no. 3 (March 16, 2016): 181—e45. http://dx.doi.org/10.1111/vde.12299.

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18

Claeys, S., J. B. Lefebvre, S. Schuller, A. Hamaide, and C. Clercx. "Surgical treatment of canine nasal aspergillosis by rhinotomy combined with enilconazole infusion and oral itraconazole." Journal of Small Animal Practice 47, no. 6 (June 2006): 320–24. http://dx.doi.org/10.1111/j.1748-5827.2006.00154.x.

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19

Mancianti, Francesca, Sara Dabizzi, and Simona Nardoni. "A lufenuron pre-treatment may enhance the effects of enilconazole or griseofulvin in feline dermatophytosis?" Journal of Feline Medicine and Surgery 11, no. 2 (February 2009): 91–95. http://dx.doi.org/10.1016/j.jfms.2008.05.006.

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20

Van Leemput, L., E. Swysen, R. Woestenborghs, L. Michielsen, W. Meuldermans, and J. Heykants. "On the terrestrial toxicity of the fungicide imazalil (enilconazole) to the earthworm species Eisenia foetida." Ecotoxicology and Environmental Safety 18, no. 3 (December 1989): 313–20. http://dx.doi.org/10.1016/0147-6513(89)90025-0.

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21

Vangrinsven, E., M. Girod, D. Goossens, L. Desquilbet, C. Clercx, and F. Billen. "Comparison of two minimally invasive enilconazole perendoscopic infusion protocols for the treatment of canine sinonasal aspergillosis." Journal of Small Animal Practice 59, no. 12 (October 25, 2018): 777–82. http://dx.doi.org/10.1111/jsap.12933.

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22

Balikci, E. "Antidermatophyte and antioxidant activities of Nigella sativa alone and in combination with enilconazole in treatment of dermatophytosis in cattle." Veterinární Medicína 61, No. 10 (October 21, 2016): 539–45. http://dx.doi.org/10.17221/32/2015-vetmed.

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23

Sharman, M., Z. Lenard, G. Hosgood, and C. Mansfield. "Clotrimazole and enilconazole distribution within the frontal sinuses and nasal cavity of nine dogs with sinonasal aspergillosis." Journal of Small Animal Practice 53, no. 3 (February 2, 2012): 161–67. http://dx.doi.org/10.1111/j.1748-5827.2011.01181.x.

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24

Ivaskiene, M., A. P. Matusevicius, A. Grigonis, G. Zamokas, and L. Babickaite. "Efficacy of Topical Therapy with Newly Developed Terbinafine and Econazole Formulations in the Treatment of Dermatophytosis in Cats." Polish Journal of Veterinary Sciences 19, no. 3 (September 1, 2016): 535–43. http://dx.doi.org/10.1515/pjvs-2016-0067.

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AbstractIn the field of veterinary dermatology dermatophytosis is one of the most frequently occurring infectious diseases, therefore its treatment should be effective, convenient, safe and inexpensive. The aim of this study was to evaluate the efficacy of newly developed topical formulations in the treatment of cats with dermatophytosis. Evaluation of clinical efficacy and safety of terbinafine and econazole formulations administered topically twice a day was performed in 40 cats. Cats, suffering from the most widely spreadMicrosporum canis-induced dermatophytosis and treated with terbinafine hydrochloride 1% cream, recovered within 20.3±0.88 days; whereas when treated with econazole nitrate 1% cream, they recovered within 28.4±1.14 days. A positive therapeutic effect was yielded by combined treatment with local application of creams and whole coat spray with enilconazole 0.2% emulsion „Imaverol”. Most cats treated with econazole cream revealed redness and irritation of the skin at the site of application. This study demonstrates that terbinafine tended to have superior clinical efficacy (p<0.001) in the treatment of dermatophytosis in cats compared to the azole tested.

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25

Guillot, J., K. Rojzner, C. Fournier, F. Touati, R. Chermette, E. Malandain, F. Jankowski, W. Seewald, and R. Schenker. "Evaluation of the efficacy of oral lufenuron combined with topical enilconazole for the management of dermatophytosis in catteries." Veterinary Record 150, no. 23 (June 8, 2002): 714–18. http://dx.doi.org/10.1136/vr.150.23.714.

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26

Cutsem, J., F. Gerven, and P. A. J. Janssen. "In Vitro Activity of Enilconazole*Against Aspergillus Spp. and its Fungicidal Efficacy in a Smoke Generator Against Aspergillus fumigatus./Die In Vitro-Aktivität von Enilconazol*gegen Aspergillus spp. und seine fungizide Aktivität gegen Aspergillus fumiga." Mycoses 31, no. 3 (April 24, 2009): 143–47. http://dx.doi.org/10.1111/j.1439-0507.1988.tb03717.x.

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27

Gogolashvili, Ann, Elene Tatunashvili, Lali Chankvetadze, Tamas Sohajda, Julianna Szeman, Antonio Salgado, and Bezhan Chankvetadze. "Separation of enilconazole enantiomers in capillary electrophoresis with cyclodextrin-type chiral selectors and investigation of structure of selector-selectand complexes by using nuclear magnetic resonance spectroscopy." ELECTROPHORESIS 38, no. 15 (April 20, 2017): 1851–59. http://dx.doi.org/10.1002/elps.201700078.

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28

Goddeeris, C., J. Coacci, and G. Van den Mooter. "Correlation between digestion of the lipid phase of smedds and release of the anti-HIV drug UC 781 and the anti-mycotic drug enilconazole from smedds." European Journal of Pharmaceutics and Biopharmaceutics 66, no. 2 (May 2007): 173–81. http://dx.doi.org/10.1016/j.ejpb.2006.10.005.

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29

Mueller, Ralf, and Cosima Bouassiba. "In-vivo-Wirksamkeit eines Ohrmedikaments mit Gelatinepulver als Wirkstoffträger bei der Therapie kaniner Otitis externa." Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere 45, no. 04 (2017): 235–44. http://dx.doi.org/10.15654/tpk-160234.

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ZusammenfassungGegenstand und Ziel: Die Therapie der Otitis externa (OE) erfolgt in der Regel durch tägliche Applikation von Lokaltherapeutika. Längere Applikationsintervalle könnten die Behandlung erleichtern. Die Studie überprüfte anhand klinischer Symptomatik sowie zytologischer und bakteriologischer/mykologischer Befunde die In-vivo-Wirksamkeit eines mit Wirkstoffen angereicherten Gelpräparats mit Marbofloxacin, Dexamethason und Enilconazol im Vergleich zu einem kommerziellen, Marbofloxacin, Dexamethason und Clotrimazol enthaltenden Otologikum. Material und Methoden: Bei 41 Hunden mit OE kam das Gelpräparat (Gruppe A) bzw. ein zugelassenes Otologikum (Gruppe B) zum Einsatz. Ausgewertet wurden 50 Ohren (je 25 pro Gruppe). Das Gelpräparat wurde an Tag 0 und 5 eingebracht und das Kombinationspräparat täglich nach Herstellerangaben appliziert. Klinische und zytologische Kontrollen fanden nach 5 und 10 Tagen statt. Zu Beginn und nach 10 Tagen wurden Tupferproben bakteriologisch sowie mykologisch untersucht. Ergebnisse: Klinisch und zytologisch ließ sich zwischen den Gruppen kein signifikanter Unterschied feststellen. In beiden Gruppen war die Steigerung negativer bakteriologischer Befunde vergleichbar. In Gruppe A wurden nach 10 Tagen signifikant mehr marbofloxacinresistente Isolate identifiziert, obwohl der Wirkstoff Marbofloxacin in vitro über einen Zeitraum von 15 Tagen noch zu über 98% verfügbar war. Schlussfolgerung: Die zweimalige Anwendung des mit definierten Wirkstoffen angefertigten Gels kann klinisch und zytologisch als vergleichbar mit der täglichen Anwendung eines zugelassenen Otologikums angesehen werden. Die Gefahr einer Resistenzentwicklung gegen Fluorchinolone ist bei Anwendung des Gels im Vergleich zu dem zugelassenen Otologikum eher vorhanden. Lokale Nebenwirkungen könnten bei Anwendung des Gels auftreten. Klinische Relevanz: Ein mit Wirkstoffen versehenes Gelatinepräparat kann bei Otitis externa des Hundes eine Alternative zur täglichen Applikation von Lokaltherapeutika sein. Die Entwicklung von Resistenzen ist möglich.

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30

Hermawan, Dadan, Ahmad Nor Shafiq Ahmad Kamali, Wan Aini Wan Ibrahim, and Mohd Marsin Sanagi. "Enantioseparation of enilconazole using cyclodextrin-modified MEKC." Malaysian Journal of Fundamental and Applied Sciences 7, no. 1 (July 24, 2014). http://dx.doi.org/10.11113/mjfas.v7n1.241.

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Enantiomeric separation of enilconazole has been successfully achieved using cyclodextrin modified micellar electrokinetic chromatography (CD-MEKC) method with HP-γ- CD as chiral selector. Two parameters which were HP-γ-CD concentration and SDS concentration have been optimized by investigating their effects on resolution and analysis time. Enantioresolution of enilconazole was achieved by the optimized CD-MEKC system containing 40 mM HP-γ- CD, 40 mM SDS and 20 mM phosphate buffer (pH 8) with resolution (Rs = 1.3) and analysis time within 9 min. Good repeatabilities were obtained in term of RSD% (n = 3) for migration time, peak area and peak height ranging from 0.07 to 6.1 %. The optimized CD-MEKC method was a simple, less solvent used, and able to perform enantiomeric separation of enilconazole with a good resolution and relatively short analysis time.

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31

KIRMIZIGÜL, Ali Haydar, Erhan GÖKÇE, Mitat ŞAHİN, Fatih BÜYÜK, and Kemal IRMAK. "Effectiveness of Enilconazole (10% pour-on) for the Treatment of Bovine Dermatophytosis." Kafkas Universitesi Veteriner Fakultesi Dergisi, 2008. http://dx.doi.org/10.9775/kvfd.2008.21-a.

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32

Rochette F. and Van Meirhaeghe P. "ENILCONAZOLE AS A TREATMENT OF NATURALLY OCCURRING DERMATOPHYTOSIS IN RABBIT FARMS : A REVIEW." World Rabbit Science 5, no. 1 (July 5, 2010). http://dx.doi.org/10.4995/wrs.1997.311.

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33

KIRMIZIGÜL, Ali Haydar, Erhan GÖKÇE, Zafer ÖZYILDIZ, Fatih BÜYÜK, and Mitat ŞAHİN. "Topical Use of Enilconazole (10%) in the Treatment of Bovine Dermatophytosis: Clinical, Mycological, and Histopatological Findings." Kafkas Universitesi Veteriner Fakultesi Dergisi, 2009. http://dx.doi.org/10.9775/kvfd.2009.001-a.

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