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Journal articles on the topic 'Enrofloxacino'

Author: Grafiati

Published: 4 June 2021

Last updated: 18 February 2022

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1

Mendes, Jéssica, Larissa Trombetta, and Andréia Amaral. "RETINOPATIA ASSOCIADA AO USO DE ENROFLOXACINO EM GATOS." Enciclopédia Biosfera 16, no. 29 (2019): 1347–64. http://dx.doi.org/10.18677/encibio_2019a121.

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2

Petrovic, Jelena, Brankica Kartalovic, Radomir Ratajac, et al. "Detection of enrofloxacine residues by microbiological screening method." Biotehnologija u stocarstvu 35, no. 1 (2019): 49–59. http://dx.doi.org/10.2298/bah1901049p.

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The usage of microbiological screening tests is widespread in control of presence of antimicrobial drug residues in meat samples. Screening tests must be capable to detect antimicrobial drug residue of interest and detection limits must comply with MRL (Maximum Residue Limit). The aim of this study was to examine the performance of a microbiological screening test with E. coli as test microorganism: capability of detecting enrofloxacina and it?s main metabolite ciprofloxacine at MRL levels in both fortified and incurred chicken tissue samples. Detection limits of microbiological screening test

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3

Alves, A. S., S. B. Araújo, J. S. Ferreira, et al. "Aspectos clínicos e terapêuticos de infecção por Mycobacterium bovis em gato doméstico - relato de caso." Arquivo Brasileiro de Medicina Veterinária e Zootecnia 71, no. 6 (2019): 1896–900. http://dx.doi.org/10.1590/1678-4162-10247.

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RESUMO Este artigo tem como objetivo relatar um caso de infecção por Mycobacterium bovis em um gato doméstico, com seis meses de idade, enfatizando seus aspectos clínicos e terapêuticos. O felino apresentava como histórico a ingestão de leite de vaca não fervido e posteriormente desenvolveu sinais de anorexia, tosse não produtiva e linfadenomegalia. Para elucidação do diagnóstico, foram realizados exames complementares de imagem, hematológicos, citológicos e reação em cadeia da polimerase (PCR). Diante da confirmação de infecção por Mycobacterium, o tratamento foi instituído por meio da associ

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4

Luiz, Leandro Da Conceição, Maria José Valenzuela Bell, and Virgílio De Carvalho Dos Anjos. "FT-NIR associado a método quimiométrico para discriminar resíduos de antimicrobianos e antiparasitário no leite." DEMETRA: Alimentação, Nutrição & Saúde 15 (December 7, 2020): e47945. http://dx.doi.org/10.12957/demetra.2020.47945.

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Introdução: O leite é um dos alimentos mais consumidos pelos seres humanos. Proteínas, vitaminas, gordura, carboidratos e sais minerais fazem parte de sua composição e desempenham importantes funções para a nutrição humana. A prática de adulteração no leite é antiga e ainda se faz presente nos dias de hoje em diversos países, inclusive no Brasil. A fim de obter lucro maior, alguns fornecedores costumam adicionar ao leite: água, amido, citrato, ureia, soda cáustica, cloreto de sódio, sacarose, soro do leite, melamina e outros componentes. No entanto, ainda há outro problema, o da contaminação d

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5

Seo, Jung Soo, Eun Ji Jeon, Eun Hye Lee, et al. "The Residues of Enrofloxacin in Cultured Paralichthys olivaceus." Journal of fish pathology 26, no. 1 (2013): 45–50. http://dx.doi.org/10.7847/jfp.2012.26.1.045.

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6

Wijayanti, Agustina Dwi, Florensia Situmorang, Akhmad Ridwan Siregar, and Novida Ariyani. "Kinetika Kadar Enrofloksasin dan Histopatologi Otot Broiler setelah Pemberian Enrofloksasin Dosis Tunggal secara Intravena." Acta VETERINARIA Indonesiana 3, no. 1 (2016): 38–43. http://dx.doi.org/10.29244/avi.3.1.38-43.

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Residu obat pada broiler akibat pemberian antibiotik sebelum panen dapat menurunkan kualitas karkas. Kerugian yang diakibatkan oleh residu pada jaringan selain terdeteksinya sejumlah obat, juga adanya kelainan patologis akibat akumulasi obat pada jaringan. Penelitian ini dilakukan untuk mengetahui efek residu yang timbul terhadap otot akibat pemberian enrofloksasin dosis 50 mg/kg berat badan secara intravena satu minggu sebelum panen. Sebanyak 18 ekor broiler strain New Loghman dipelihara sejak day old chick (DOC) hingga umur 30 hari dan mencapai berat badan rata-rata 1,0-1,5 kg. Sebanyak 15 e

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7

Prous, J., and J. Castañer. "Enrofloxacin." Drugs of the Future 13, no. 4 (1988): 305. http://dx.doi.org/10.1358/dof.1988.013.04.62402.

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8

Mitchell, Mark A. "Enrofloxacin." Journal of Exotic Pet Medicine 15, no. 1 (2006): 66–69. http://dx.doi.org/10.1053/j.jepm.2005.11.011.

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9

Schoevers, E. J., L. A. M. G. van Leengoed, J. H. M. Verheijden, and T. A. Niewold. "Effects of Enrofloxacin on Porcine Phagocytic Function." Antimicrobial Agents and Chemotherapy 43, no. 9 (1999): 2138–43. http://dx.doi.org/10.1128/aac.43.9.2138.

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ABSTRACT The interaction between enrofloxacin and porcine phagocytes was studied with clinically relevant concentrations of enrofloxacin. Enrofloxacin accumulated in phagocytes, with cellular concentration/extracellular concentration ratios of 9 for polymorphonuclear leukocytes (PMNs) and 5 for alveolar macrophages (AMs). Cells with accumulated enrofloxacin brought into enrofloxacin-free medium released approximately 80% (AMs) to 90% (PMNs) of their enrofloxacin within the first 10 min, after which no further release was seen. Enrofloxacin affected neither the viability of PMNs and AMs nor the

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10

Sasaki, Hiraku, Eiichi Kawamoto, Satoshi Kunita, and Ken-ichi Yagami. "Comparison of the in Vitro Susceptibility of Rodent Isolates of Pseudomonas Aeruginosa and Pasteurella Pneumotropica to Enrofloxacin." Journal of Veterinary Diagnostic Investigation 19, no. 5 (2007): 557–60. http://dx.doi.org/10.1177/104063870701900517.

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The objectives of this study were to determine and compare the in vitro enrofloxacin susceptibility of 94 Pseudomonas aeruginosa isolates obtained from enrofloxacin-treated and untreated mice and that of 40 Pasteurella pneumotropica strains and also to assess the efficacy and effects of enrofloxacin treatment of laboratory mice. The minimum inhibitory concentrations (MICs) of enrofloxacin against all the Ps. aeruginosa isolates were in the range of 1 to 4 μg/ml, whereas those against all the P. pneumotropica strains were less than 0.5 μg/ml. The mutation frequency in 54% of the Ps. aeruginosa

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11

Parshikov, Igor A., James P. Freeman, Jackson O. Lay, Richard D. Beger, Anna J. Williams, and John B. Sutherland. "Microbiological Transformation of Enrofloxacin by the Fungus Mucor ramannianus." Applied and Environmental Microbiology 66, no. 6 (2000): 2664–67. http://dx.doi.org/10.1128/aem.66.6.2664-2667.2000.

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ABSTRACT Enrofloxacin metabolism by Mucor ramannianus was investigated as a model for the biotransformation of veterinary fluoroquinolones. Cultures grown in sucrose-peptone broth were dosed with enrofloxacin. After 21 days, 22% of the enrofloxacin remained. Three metabolites were identified: enrofloxacin N-oxide (62% of the total absorbance), N-acetylciprofloxacin (8.0%), and desethylene-enrofloxacin (3.5%).

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12

Kim, Poong-Ho, Hee-Jung Lee, Mi-Ra Jo, Tae-Seek Lee, and Jin-Hwan Ha. "Withdrawal Time of Enrofloxacin in Oliver Flounder (Paralichthys olivaceus) after Oral Administration." Korean Journal of Fisheries and Aquatic Sciences 39, no. 2 (2006): 72–77. http://dx.doi.org/10.5657/kfas.2006.39.2.072.

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13

McKay, Lindsay, Crystal D. Schuman Rose, Jennifer L. Matousek, Lynn S. Schmeitzel, Nicole M. Gibson, and Jack M. Gaskin. "Antimicrobial Testing of Selected Fluoroquinolones Against Pseudomonas aeruginosa Isolated From Canine Otitis." Journal of the American Animal Hospital Association 43, no. 6 (2007): 307–12. http://dx.doi.org/10.5326/0430307.

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A total of 100 Pseudomonas aeruginosa (P. aeruginosa) isolates were collected over a 1.5- year period from cases of canine otitis. Sensitivities to enrofloxacin, marbofloxacin, and orbifloxacin were determined using minimum inhibitory concentration testing (MICT). Isolates were also tested for sensitivities to enrofloxacin and marbofloxacin using disk-diffusion susceptibility testing (DDST). Isolates were significantly more sensitive to marbofloxacin than to enrofloxacin (z = −4.57; P&lt;0.05) or orbifloxacin (z = −5.02; P&lt;0.05). Agreement was 87% between MICT and DDST for marboflox

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14

Yurin, D. V., V. V. Nevzorova, A. A. Balbutskaya, and S. S. Belimova. "Antimicrobial activity of enrofloxacin in vitro." International bulletin of Veterinary Medicine 2 (2020): 99–103. http://dx.doi.org/10.17238/issn2072-2419.2020.2.99.

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Continuouse use of enrofloxacin contributes to emergence of enrofloxacin-resistant mi-crobial resistance, isolated and reported late-ly. In this study we deal with the spread of resistance of enrofloxacin among pathogenic organisms, infecting animals. The suscepti-bility to enrofloxacin was studied in standard disc diffusion assay. We studied 437 bacteri-al isolates in total. Salmonella dublin and Sal-monella typhimurium showed the highest suscepti-bility to enrofloxacin (100%); Salmonella enter-itidis and Salmonella choleraesuis proved a bit less susceptibility (95% and 94,7%). 5% of S. enter

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15

McKellar, Quintin, Ian Gibson, Ana Monteiro, and Miguel Bregante. "Pharmacokinetics of Enrofloxacin and Danofloxacin in Plasma, Inflammatory Exudate, and Bronchial Secretions of Calves following Subcutaneous Administration." Antimicrobial Agents and Chemotherapy 43, no. 8 (1999): 1988–92. http://dx.doi.org/10.1128/aac.43.8.1988.

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ABSTRACT Enrofloxacin (2.5 mg/kg of body weight) and danofloxacin (1.25 mg/kg) were administered subcutaneously to ruminating calves (n = 8) fitted with subcutaneous tissue cages. Concentrations of enrofloxacin, its metabolite ciprofloxacin, and danofloxacin in blood (plasma), tissue cage exudate (following intracaveal injection of 0.3 ml of 1% [vol/wt] carrageenan), and bronchial secretions were measured by high-performance liquid chromatography (HPLC) and microbiological assay (enrofloxacin plus ciprofloxacin and danofloxacin). Mean maximum concentrations (C max) ± standard deviations of enr

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16

Inglis, G. Douglas, Sarah J. M. Zaytsoff, L. Brent Selinger, Eduardo N. Taboada, and Richard R. E. Uwiera. "Therapeutic administration of enrofloxacin in mice does not select for fluoroquinolone resistance inCampylobacter jejuni." Canadian Journal of Microbiology 64, no. 10 (2018): 681–94. http://dx.doi.org/10.1139/cjm-2017-0741.

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Enrofloxacin is registered for therapeutic use in beef cattle to treat bovine respiratory disease in Canada. A murine model was used to experimentally examine the impact of therapeutic administration of enrofloxacin on fluoroquinolone resistance development in Campylobacter jejuni. Administration of enrofloxacin to mice via subcutaneous injection or per os routes resulted in equivalent levels of bioactive enrofloxacin within the intestine, but bioactivity was short-lived (<48 h after cessation). Enrofloxacin administration did not affect densities of total bacteria, Firmicutes, or Bacteroid

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17

Perkasa, Genta Sapta Bayu, Armen Nainggolan, and Yudha Lestira Dhewantara. "Uji Sensitivitas Antibiotik Terhadap Bakteri Aeromonas hydrophilla dan Edwardsiella tarda Skala Laboratorium (In Vitro)." Jurnal Ilmiah Satya Minabahari 5, no. 1 (2019): 10–17. http://dx.doi.org/10.53676/jism.v5i1.73.

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Bakteri Aeromonas hydrophilla dan Edwardsiella tarda merupakan bakteri yang berbahaya bagi budidaya ikan air tawar. Penelitian ini bertujuan untuk mengetahui dan membandingkan daya hambat dan sensitivitas bakteri Aeromonas hydrophilla dan Edwardsiella tarda terhadap suatu antibiotik. Penelitian ini menggunakan 3 macam antibiotik dan 3 kali ulangan, yaitu perlakuan A (bakteri Aeromonas hydrophilla diberi antibiotik novobiocin, enrofloxacin baytril dan DD15 0129) dan perlakuan B (bakteri Edwardsiella tarda diberi antibiotik novobiocin, enrofloxacin baytril dan DD15 0129). Media yang digunakan ad

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18

Widiyanti, Prima Mei, Mirnawati Bachrum Sudarwanto, Etih Sudarnika, and Raphaella Widiastuti. "The Use of Enrofloxacin Antibiotic as a Veterinary Drug and Its Residual Hazards on Public Health." Indonesian Bulletin of Animal and Veterinary Sciences 29, no. 2 (2019): 75. http://dx.doi.org/10.14334/wartazoa.v29i2.2015.

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The livestock sector can improve the community's economy and has a role in fulfilling food needs, especially animal protein. One of the problems in the livestock sector is the presence of infectious diseases that consequently need treatment using veterinary drugs. This paper describes the use of enrofloxacin antibiotics as veterinary drug and their residual hazards on public health. Enrofloxacin is an antibiotic from the family of fluoroquinolones (second generation of quinolone). Enrofloxacin is a broad-spectrum antibiotic that is effective to kill Gram positive and negative bacteria, so it w

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19

Fassi Fehri, Lina, Henri Wróblewski, and Alain Blanchard. "Activities of Antimicrobial Peptides and Synergy with Enrofloxacin against Mycoplasma pulmonis." Antimicrobial Agents and Chemotherapy 51, no. 2 (2006): 468–74. http://dx.doi.org/10.1128/aac.01030-06.

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ABSTRACT We showed in a previous study that associations of antimicrobial peptides (AMPs), which are key components of the innate immune systems of all living species, with the fluoroquinolone enrofloxacin can successfully cure HeLa cell cultures of Mycoplasma fermentans and M. hyorhinis contamination. In the present work, the in vitro susceptibility of M. pulmonis, a murine pathogen, to enrofloxacin and four AMPs (alamethicin, globomycin, gramicidin S, and surfactin) was investigated, with special reference to synergistic associations and the effect of the mycoplasma cell concentration. Enrof

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Wildermuth, Brett Everett, Craig E. Griffin, Wayne S. Rosenkrantz, and Mona J. Boord. "Susceptibility of Pseudomonas Isolates From the Ears and Skin of Dogs to Enrofloxacin, Marbofloxacin, and Ciprofloxacin." Journal of the American Animal Hospital Association 43, no. 6 (2007): 337–41. http://dx.doi.org/10.5326/0430337.

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The purpose of this study was to compare susceptibilities of ear and skin Pseudomonas spp. isolates to enrofloxacin, marbofloxacin, and ciprofloxacin. Specimens were obtained from dogs examined in a veterinary dermatology referral hospital. Susceptibilities of ear isolates to enrofloxacin, marbofloxacin, and ciprofloxacin were 46.9%, 66.7%, and 75.0%, respectively. Susceptibilities of skin isolates to the same drugs were 76.2%, 81.0%, and 80.0%, respectively. Ear isolates were significantly less susceptible to enrofloxacin than to ciprofloxacin (P=0.021), and ear isolates were significantly le

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21

Rosskopf, Walter J. "Use of Enrofloxacin." Bulletin of the Association of Reptilian and Amphibian Veterinarians 2, no. 1 (1992): 5–6. http://dx.doi.org/10.5818/1076-3139-2.1.5e.

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22

Miranda-Calderón, Jorge E., Lilia Gutiérrez, Marcos Flores-Alamo, Ponciano García-Gutiérrez, and Héctor Sumano. "Enrofloxacin hydrochloride dihydrate." Acta Crystallographica Section E Structure Reports Online 70, no. 4 (2014): o468—o469. http://dx.doi.org/10.1107/s1600536814006059.

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The asymmetric unit of the title compound, C19H23FN3O3+·Cl−·2H2O [systematic name: 4-(3-carboxy-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinolin-7-yl)-1-ethylpiperazin-1-ium chloride dihydrate], consists of two independent monocations of the protonated enrofloxacin, two chloride anions and four water molecules. In the cations, the piperazinium rings adopt chair conformations and the dihedral angles between the cyclopropyl ring and the 10-membered quinoline ring system are 56.55 (2) and 51.11 (2)°. An intramolecular O—H...O hydrogen bond is observed in each cation. In the crystal, the component

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23

Dick, G. "Use of enrofloxacin." Veterinary Record 132, no. 24 (1993): 616. http://dx.doi.org/10.1136/vr.132.24.616.

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24

Rebouças, Camila Tavares, Ana Carolina Kogawa, and Hérida Regina Nunes Salgado. "A New Green Method for the Quantitative Analysis of Enrofloxacin by Fourier-Transform Infrared Spectroscopy." Journal of AOAC INTERNATIONAL 101, no. 6 (2018): 2001–5. http://dx.doi.org/10.5740/jaoacint.17-0431.

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Abstract Background: A green analytical chemistry method was developed for quantification of enrofloxacin in tablets. The drug, a second-generation fluoroquinolone, was first introduced in veterinary medicine for the treatment of various bacterial species. Objective: This study proposed to develop, validate, and apply a reliable, low-cost, fast, and simple IR spectroscopy method for quantitative routine determination of enrofloxacin in tablets. Methods: The method was completely validated according to the International Conference on Harmonisation guidelines, showing accuracy, precision, select

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Abdulhamza, Nibras Naeb. "Neurotoxic and Teratogenic Effects of Enrofloxacin Against Newly Hatched Chicks Subjected to Omphalitis." Iraqi Journal of Veterinary Medicine 43, no. 1 (2019): 113–23. http://dx.doi.org/10.30539/iraqijvm.v43i1.481.

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This study was aimed to investigate any possible neurotoxic signs and teratogenic anomalies that may result from pre incubation dipping of fertile eggs in Enrofloxacin concentrations as a preventive measurement against omphalitis. E. Coli sensitivity against Enrofloxacin was examined in a dose dependent manner by using 2, 4, 6, 8, and 10 µg/ml. Forty two non-infected newly hatched chicks at age of 5-7 days were divided into six groups of seven chicks each, subjected to behavioral tests namely; Open Field Test and Tonic Immobility Test. For Open Field Test results showed that the lowest latency

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Mason, Sharon E., Mark G. Papich, Michael C. Schmale, Craig A. Harms, and Sally A. Davis. "Enrofloxacin Pharmacokinetics and Sampling Techniques in California Sea Hares (Aplysia californica)." Journal of the American Association for Laboratory Animal Science 58, no. 2 (2019): 231–34. http://dx.doi.org/10.30802/aalas-jaalas-18-000072.

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This pharmacokinetic study was designed to determine the pharmacokinetics of enrofloxacin at 5 mg/kg when given to sea hares in their hemolymph. Enrofloxacin is a commonly used antimicrobial in veterinary medicine and potentially could be used to treat sea hares exposed to susceptible bacterial species. We individually identified 8 juvenile Aplysia californica and group housed them in an open seawater flow system at 14 to 18 °C; 2 served as untreated controls. The remaining 6 animals were injected into the hemocoel with 0.030 mL of 22.7 mg/mL enrofloxacin (average dose, 5 to 6 mg/kg). At each

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Moorer, Jeremiah D., Heather A. Towle-Millard, Marjorie E. Gross, and Mark E. Payton. "Effects of Ampicillin/Sulbactam and Enrofloxacin on the Blood Pressure of Isoflurane Anesthetized Dogs." Journal of the American Animal Hospital Association 49, no. 5 (2013): 293–300. http://dx.doi.org/10.5326/jaaha-ms-5899.

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A blinded, prospective, randomized crossover study was performed to determine the effects of ampicillin Na/sulbactam Na and enrofloxacin on the blood pressure (BP) of healthy anesthetized dogs. Eight dogs were anesthetized three different times. They randomly received enrofloxacin, ampicillin Na/sulbactam Na, and saline. Systolic, diastolic, and mean arterial BPs (SAP, DAP, and MAP, respectively), heart rate (HR), O2 saturation of hemoglobin, end-tidal CO2 (ETCO2) concentration, inspired isoflurane concentration, end-tidal isoflurane (ETiso) concentration, respiratory rate, electrocardiogram,

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Lysnyansky, I., I. Gerchman, I. Mikula, F. Gobbo, S. Catania, and S. Levisohn. "Molecular Characterization of Acquired Enrofloxacin Resistance in Mycoplasma synoviae Field Isolates." Antimicrobial Agents and Chemotherapy 57, no. 7 (2013): 3072–77. http://dx.doi.org/10.1128/aac.00203-13.

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ABSTRACTThein vitroactivity of enrofloxacin against 73Mycoplasma synoviaefield strains isolated in Israel and Europe was determined by broth microdilution. Decreased susceptibility to enrofloxacin was identified in 59% of strains, with the MICs ranging from 1 to >16 μg/ml. The estimated MIC50and MIC90values for enrofloxacin were 2 and 8 μg/ml, respectively. Moreover, this study showed that 92% of recent Israeli field isolates (2009 to 2011) ofM. synoviaehave MICs of ≥2 μg/ml to enrofloxacin. Comparison of the quinolone resistance-determining regions (QRDRs) inM. synoviaeisolates revealed a

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Kang, JeongWoo, Md Akil Hossain, Hae-chul Park, Ok me Jeong, Sung-won Park, and Moon Her. "Cross-Contamination of Enrofloxacin in Veterinary Medicinal and Nutritional Products in Korea." Antibiotics 10, no. 2 (2021): 128. http://dx.doi.org/10.3390/antibiotics10020128.

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Poultry meat and eggs are vital sources of protein for human consumption worldwide. The use of several nutritional and medicinal products, including antibiotics, is crucial for efficient and safe poultry production. Accumulation of drug residues in meat and eggs from inappropriate drug use is a major concern to public health. Recently, enrofloxacin was detected (2.4–3.8 ppb) in edible eggs produced in Jeju Island, Korea. Although the farm from which the enrofloxacin-contaminated eggs were collected did not use enrofloxacin-containing products, they reported extensive use of a nutritional produ

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Petrović, Jelena, Marcela Šepernada, S. Stefanović, M. Ž. Baltić, Radomir Ratajac, and Jelena Apić. "THERAPEUTICAL USAGE OF FLUOROQUINOLONES IN POULTRY PRODUCTION INFLUENCE ON MEAT SAFETY – RESIDUES IN EDIBLE TISSUES." Archives of Veterinary Medicine 4, no. 2 (2012): 3–9. http://dx.doi.org/10.46784/e-avm.v4i2.181.

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Current most important side effects of antimicrobial drugs usage are veterinary drug residues in edible animal tissues and development of resistance in food borne pathogens. Enrofloxacine and flumequine are fluoroquinolone antimicrobials licensed in Serbia for use in poultry treatment. Elimination of health risk for consumers is usually made by examination of the target tissue residues of flumequine and enrofloxacine (with its main metabolite ciprofloxacine). After correct application of enrofloxacine and flumequine tissue residue levels descrease to permitted quantities (below MRL) (Maximum R

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Butaye, P., R. Ducatelle, P. De Backer, H. Vermeersch, J. P. Remon, and F. Haesebrouck. "In vitro activities of doxycycline and enrofloxacin against European Chlamydia psittaci strains from turkeys." Antimicrobial Agents and Chemotherapy 41, no. 12 (1997): 2800–2801. http://dx.doi.org/10.1128/aac.41.12.2800.

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The in vitro susceptibility of 14 European Chlamydia psittaci strains from turkeys to the antibiotics doxycycline and enrofloxacin was tested. For doxycycline the MIC ranged from 0.05 to 0.2 microg/ml, with an average of 0.1 microg/ml. For enrofloxacin the MIC was 0.25 microg/ml. Acquired resistance was not detected against doxycycline and enrofloxacin.

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Asambe, A., M. Babashani, and U. S. Salisu. "In vitro comparative activity of ciprofloxacin and enrofloxacin against clinical isolates from chickens in Benue State, Nigeria." Nigerian Veterinary Journal 39, no. 3 (2018): 199–208. http://dx.doi.org/10.4314/nvj.v39i3.3.

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This study compares the in vitro activities of enrofloxacin and its main metabolite ciprofloxacin against clinical Escherichia coli and non-lactose fermenting enterobacteria isolates from chickens. Ten (10) Escherichia coli and 8 non lactose fermenting enterobacteriaceae species isolated from a pool of clinical cases at the Microbiology Laboratory of the Veterinary Teaching Hospital, University of Agriculture Makurdi were used in this study. Ten-fold serial dilution of 10 varying concentrations (0.1-50μg/mL) of enrofloxacin and ciprofloxacin were tested against the isolates in vitro by Bauer’s

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Pomorska-Mól, Małgorzata, Ewelina Czyżewska-Dors, Krzysztof Kwit та Zygmunt Pejsak. "Enrofloxacin decreases IL-6 and TNF-α production by lipopolysaccharide-stimulated porcine peripheral blood mononuclear cells". Journal of Veterinary Research 60, № 2 (2016): 189–93. http://dx.doi.org/10.1515/jvetres-2016-0028.

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Abstract Introduction: The aim of the study was to explore the effect of enrofloxacin on production of selected cytokines by porcine peripheral blood mononuclear cells (PBMCs). Material and Methods: Twenty pigs (10 control and 10 experimental) were used in this research. Pigs from experimental group received enrofloxacin at therapeutic doses. Blood samples were collected before, during, and after treatment with enrofloxacin. PBMCs were incubated with or without lipopolysaccharide (LPS). Production of IL-6, IL-10, INF-γ, and TNF-α were determined by ELISA. Results: Administration of enrofloxaci

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Khan, Adil Mehraj, Satyavan Rampal, and Naresh Kumar Sood. "Effect of repeated oral administration of levofloxacin, enrofloxacin, and meloxicam on antioxidant parameters and lipid peroxidation in rabbits." Human & Experimental Toxicology 36, no. 1 (2016): 42–50. http://dx.doi.org/10.1177/0960327116637111.

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The effect of 21 days of repeated oral administration of levofloxacin and enrofloxacin both alone and in combination with meloxicam, on the oxidative balance in blood was evaluated in rabbits. Rabbits were randomly allocated to six groups of four animals each. Control group was gavaged 5% dextrose and 2% benzyl alcohol. Three groups were exclusively gavaged meloxicam (0.2 mg/kg body weight o.d.), levofloxacin hemihydrate (10 mg/kg body weight b.i.d 12 h), and enrofloxacin (20 mg/kg body weight o.d.), respectively. Two other groups were co-gavaged meloxicam with levofloxacin hemihydrate and enr

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Bachinskaya, V. M., Obaida Maarouf, and Yu V. Petrova. "Efficiency of application and Biosafety of products of slaughter of broiler chickens when using antibiotics." Veterinariya, Zootekhniya i Biotekhnologiya 1, no. 8 (2020): 12–17. http://dx.doi.org/10.36871/vet.zoo.bio.202008002.

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The article presents experimental data on the detection of antibiotics enrofloxacin and ciprofloxacin in poultry meat. We also analyzed the timing of removal of these antibacterial drugs from the poultry body and assessed the biological safety of products of slaughter of broiler chickens. These studies were conducted in the Syrian Arab Republic. It is established that in the free sale cases of sale of chicken meat containing enrofloxacin are detected. This is probably due to the fact that poultry is slaughtered before treatment is completed. On the contrary, such an antibacterial drug as cipro

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Agudelo Ramírez, Carlos Fernando, Peter Scheer, and Jaroslava Tomenendálová. "Effects of parenteral administration of enrofloxacin on electrocardiographic parameters in hospitalized dogs." Acta Veterinaria Brno 81, no. 4 (2012): 409–14. http://dx.doi.org/10.2754/avb201281040409.

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The effect of enrofloxacin on the QT interval of the electrocardiogram was studied in 30 hospitalized dogs. The experimental group (n = 15) received enrofloxacin parenterally (subcutaneously) at a dose of 5 mg/kg twice daily and amoxicillin-clavulanate intravenously at a dose of 22 mg/kg three times daily. The control group (n = 15) received only amoxicillin-clavulanate. Electrocardiography was carried out for 5 min once daily for 6 days. The QT interval was corrected by four different formulae. No differences were found between the two groups or within each group for the duration of the study

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Pomorska-Mól, Małgorzata, and Zygmunt Pejsak. "Effect of therapeutic doses of enrofloxacin on circulating lymphocyte subpopulations in pigs." Bulletin of the Veterinary Institute in Pulawy 59, no. 2 (2015): 287–93. http://dx.doi.org/10.1515/bvip-2015-0042.

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AbstractTwenty pigs of similar genetics (PIC) were used. Pigs were randomly divided into two groups: experimental (ENRO, n = 10) and control (C, n = 10). From day 0 to day 4, pigs from ENRO group received enrofloxacin at the recommended therapeutic dose. Pigs from C group received PBS instead of enrofloxacin. Blood samples were collected on days 0 (before antibiotic administration), 2, 4 (during antibiotic therapy), 9, and 13 of the study (after enrofloxacin administration). Haematological examination and flow cytometry were used to establish the relative and absolute counts of various leukocy

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Lysnyansky, I., I. Mikula, I. Gerchman, and S. Levisohn. "Rapid Detection of a Point Mutation in the parC Gene Associated with Decreased Susceptibility to Fluoroquinolones in Mycoplasma bovis." Antimicrobial Agents and Chemotherapy 53, no. 11 (2009): 4911–14. http://dx.doi.org/10.1128/aac.00703-09.

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ABSTRACT Comparison of the quinolone resistance-determining regions (QRDRs) in 42 Mycoplasma bovis clinical isolates revealed amino acid substitutions at both GyrA (position 83) and ParC (position 84) in 10/11 enrofloxacin-resistant strains. The mutation present in the parC QRDR was discriminative for enrofloxacin resistance by parC PCR-restriction fragment length polymorphism. Comparison of molecular profiles by insertion sequence typing suggests that the currently prevalent enrofloxacin-resistant M. bovis strain evolved by selection under field conditions from one of the susceptible strains.

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Babaahmady, Ebrahim. "Toxicology of baytril (enrofloxacin)." African Journal of Pharmacy and Pharmacology 5, no. 18 (2011): 2042–45. http://dx.doi.org/10.5897/ajpp11.644.

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Lizondo, Mònica, Miquel Pons, Montserrat Gallardo, and Joan Estelrich. "Physicochemical properties of enrofloxacin." Journal of Pharmaceutical and Biomedical Analysis 15, no. 12 (1997): 1845–49. http://dx.doi.org/10.1016/s0731-7085(96)02033-x.

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e Souza, Marinês J., Celso F. Bittencourt, and Lisoni M. Morsch. "LC determination of enrofloxacin." Journal of Pharmaceutical and Biomedical Analysis 28, no. 6 (2002): 1195–99. http://dx.doi.org/10.1016/s0731-7085(01)00673-2.

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Melo, I. M. F., W. E. Silva, A. A. C. Teixeira, et al. "Efeito da enrofloxacina sobre a interação blastocisto endométrio e seu reflexo no desenvolvimento placentário e fetal em ratas." Arquivo Brasileiro de Medicina Veterinária e Zootecnia 66, no. 5 (2014): 1406–12. http://dx.doi.org/10.1590/1678-5594.

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Estudos têm mostrado efeitos tóxicos da enrofloxacina em diversos tecidos. Assim, testou-se a hipótese de que a enrofloxacina pode interferir no desenvolvimento placentário e gerar efeitos adversos ao feto. A enrofloxacina (Baytril(r)) foi administrada em ratas, na dose de 5mg/kg, diariamente, IM, durante toda a gestação. As placentas foram analisadas morfologicamente, morfometricamente e imuno-histoquimicamente aos sete, 14 e 21 dias de prenhez. Os resultados mostraram que a enrofloxacina reduziu o número de sítios de implantação, o peso e a área total do disco placentário aos 14 e 21 dias de

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Leyva-Molina, Cesar Martin, Mariel Aybar Espinoza, Andrea Carhuallanqui Pérez, and Daphne Doris Ramos Delgado. "Detección de residuos de enrofloxacina por microbiología (prueba de inhibición del crecimiento) y ELISA en cuyes (Cavia porcellus) en la provincia de Jauja, Perú." Revista de Investigaciones Veterinarias del Perú 31, no. 3 (2020): e18726. http://dx.doi.org/10.15381/rivep.v31i3.18726.

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El presente estudio tuvo como objetivo detectar la posible presencia de enrofloxacina en cuyes destinados al consumo humano en la provincia de Jauja, Región Junín, Perú. Para la detección de enrofloxacina se tomaron muestras de hígado, riñón y diafragma de 200 cuyes de dos mataderos de la provincia de Jauja. La detección de residuos de antibióticos se realizó utilizando la prueba microbiológica de Inhibición del Crecimiento en las tres muestras, obteniéndose resultados negativos en todas ellas. Se tomaron al azar 30 de estas muestras y se analizaron mediante la prueba de ELISA con un kit comer

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Zhu, Fengjiao, Zongying Yang, Yiliu Zhang, Kun Hu, and Wenhong Fang. "Transcriptome differences between enrofloxacin-resistant and enrofloxacin-susceptible strains of Aeromonas hydrophila." PLOS ONE 12, no. 7 (2017): e0179549. http://dx.doi.org/10.1371/journal.pone.0179549.

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Liu, Chune, Hong Lin, Limin Cao, and Jie Jiang. "Anti-enrofloxacin antibody production by using enrofloxacin-screened HSA as an immunogen." Journal of Ocean University of China 4, no. 3 (2005): 262–66. http://dx.doi.org/10.1007/s11802-005-0045-z.

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Spodniewska, A., and D. Barski. "Concentration of hepatic vitamins A and E in rats exposed to chlorpyrifos and/or enrofloxacin." Polish Journal of Veterinary Sciences 19, no. 2 (2016): 371–78. http://dx.doi.org/10.1515/pjvs-2016-0046.

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Abstract The aim of the study was to determine the level of antioxidant vitamins A and E in the liver of rats exposed to chlorpyrifos and/or enrofloxacin. Chlorpyrifos (Group I) was administered at a dose of 0.04 LD50 (6 mg/kg b.w.) for 28 days, and enrofloxacin (Group II) at a dose of 5 mg/kg b.w. for 5 consecutive days. The animals of group III were given both of the mentioned above compounds at the same manner as groups I and II, but enrofloxacin was applied to rats for the last 5 days of chlorpyrifos exposure (i.e. on day 24, 25, 26, 27 and 28). Chlorpyrifos and enrofloxacin were administe

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Nedbalcová, Kateřina, Kateřina Nechvátalová, and Zdeňka Kučerová. "Determination of the minimum inhibitory concentration (MIC) and mutant prevention concentration (MPC) of selected antimicrobials in bovine and swine Pasteurella multocida, Escherichia coli, and Staphylococcus aureus isolates." Acta Veterinaria Brno 84, no. 2 (2015): 83–89. http://dx.doi.org/10.2754/avb201584020083.

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We compared the values of the minimum inhibitory concentration (MIC) and mutant prevention concentration (MPC) values of three antimicrobial agents for 72 bovine isolates ofPasteurella multocida, 80 swine isolates ofP. multocida, 80 bovine isolates ofEscherichia coli, 80 swine isolates ofE. coli, and 80 isolates ofStaphylococcus aureusfrom bovine mastitis. The ratio of MIC90/MPC90which limited mutant selection window (MSW) was ≤ 0.12/4 mg/l for enrofloxacin, 0.5/≥ 64 mg/l for florfenicol and 4/≥ 128 mg/l for tulathromycin in bovineP. multocidaisolates, ≤ 0.12/2 mg/l for enrofloxacin, 0.5/≥

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Bideci, Gül Banu Çiçek, and Sezai Kaya. "The Investigation of the Pharmacokinetics of Two Enrofloxacin Preparations Following Parenteral Administration in Calves." Acta Scientiae Veterinariae 46, no. 1 (2018): 6. http://dx.doi.org/10.22456/1679-9216.81830.

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Background: Enrofloxacin is a bactericidal antimicrobial drug in the fluoroquinolone group, developed for use only in the veterinary field. It is effective against gram negative and gram positive bacteria, Mikoplazma, Rickettsia, Ehrlichia ve Chlamydia. Enrofloxacin is converted to several effective and ineffective metabolites including ciprofloxacin. Ten to fifty percent of the drug is eliminated via urine and bile in unmetabolized form. Enrofloxacin is used in all domestic animal including ruminant and winged animals. In calves, enrofloxacin finds utilization in the respiratory system infect

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Pang, Hong, Yu-Bin Sun, Jun-Wen Zhou, et al. "Pharmaceutical Salts of Enrofloxacin with Organic Acids." Crystals 10, no. 8 (2020): 646. http://dx.doi.org/10.3390/cryst10080646.

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Enrofloxacin is a poorly soluble antibacterial drug of the fluoroquinolones class used in veterinary medicine. The main purpose of this work was to investigate the structural and pharmaceutical properties of new enrofloxacin salts. Enrofloxacin anhydrate and its organic salts with tartaric acid, nicotinic acid and suberic acid formed as pure crystalline anhydrous solids. All the crystals were grown from a mixed solution by slow evaporation at room temperature. These products were then characterized by field-emission scanning electron microscopy, powder X-ray diffraction, Fourier transform infr

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Malorny, Burkhard, Andreas Schroeter, and Reiner Helmuth. "Incidence of Quinolone Resistance Over the Period 1986 to 1998 in Veterinary Salmonella Isolates from Germany." Antimicrobial Agents and Chemotherapy 43, no. 9 (1999): 2278–82. http://dx.doi.org/10.1128/aac.43.9.2278.

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ABSTRACT A total of 24,591 nonhuman salmonella strains isolated in Germany between 1986 and 1998 were examined for their resistance to nalidixic acid by an agar diffusion method. The rate of resistance (inhibition zone, ≤13 mm) ranged from 0.2% in 1986 to a peak of 14.8% in 1990. Between 1991 and 1998 the MICs for nalidixic acid-resistant strains ranged from more than 256 μg/ml for nalidixic acid to between 0.25 and 128 μg/ml for enrofloxacin. In the early 1990s a particularly high incidence of fluoroquinolone resistance (49.5%) was seen among isolates of Salmonella enterica serotype Typhimuri

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