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1

Peters, I. O. M., A. Willemsen, J. J. de Bruyne, and R. C. Nap. "Aspirin Medication in Dogs." Veterinary and Comparative Orthopaedics and Traumatology 4, no. 03 (1991): 95–99. http://dx.doi.org/10.1055/s-0038-1633260.

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SummaryAspirin (acetylsalicylic acid; ASA) is widely used in both human and veterinary medicine. Therapeutic plasma salicylate concentrations (PSCs) can be reached using enteric-coated ASA tablets, but a delay in the initial rise and large fluctuations in the PSCs have been reported. From experiments described previously, the authors concluded that the large type enteric-coated ASA tablets were not suitable for use in beagle dogs.In the first experiment described here, these large type tablets were administered to large mongrel dogs. Although the mean PSC reached therapeutic levels after 44 h,
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2

Patel, Hetal, and Mukesh Gohel. "A Review on Enteric Coated Pellets Composed of Core Pellets Prepared by Extrusion-Spheronization." Recent Patents on Drug Delivery & Formulation 13, no. 2 (2019): 83–90. http://dx.doi.org/10.2174/1872211313666190212115139.

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Enteric coated dosage form bypasses the stomach and releases the drug into the small intestine. Advantages of enteric coated pellets in comparison with enteric coated tablets are a) Pellets provide rapid onset of action and faster drug release due to the smaller size than tablets and b) Pellets exhibit less residence time of acid-labile drugs in the stomach compared to tablets. Dosage form coat can be damaged by longer resistance time in the stomach. The present review summarizes the current state of enteric coated pellets where core pellets are prepared by extrusion-spheronization technique a
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3

Godge, GR, and SN Hiremath. "Development and evaluation of colon targeted drug delivery system by using natural Polysaccharides/Polymers." Dhaka University Journal of Pharmaceutical Sciences 13, no. 1 (2015): 105–13. http://dx.doi.org/10.3329/dujps.v13i1.21874.

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Colon is being extensively investigated as a drug delivery site. This study contains comparison of the usual enteric coating polymers viz. xanthan gum, guar gum, chitosan and ethyl cellulose, as carriers for colon specific drug delivery. Lactose based metoprolol succinate tablets were prepared. These were coated with one of the coating polymers to a varying coat thickness. Tablets were prepared using polysaccharides or synthetic polymer as binders. These included xanthan gum, guar gum, chitosan and ethyl cellulose. Metoprolol Succinate was used as a model drug. The prepared tablets were enteri
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4

Parys, Wioletta, Alina Pyka-Pająk, and Małgorzata Dołowy. "Application of Thin-Layer Chromatography in Combination with Densitometry for the Determination of Diclofenac in Enteric Coated Tablets." Pharmaceuticals 12, no. 4 (2019): 183. http://dx.doi.org/10.3390/ph12040183.

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Diclofenac belongs to the drug class non-steroidal anti-inflammatory drugs widely used in Europe as well as all over the world. Thus, it is important to conduct research on its quality control of available pharmaceutical preparations like for example enteric coated tablets. Among various analytical techniques, thin-layer chromatography (TLC) is ideal for this task due to their short time analysis, ease of operation and low cost. Hence, the aim of this study was to develop the optimal conditions of analysis and quantitative determination of diclofenac sodium in enteric tablets by using TLC in c
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5

Doye, Pakpi, Tanya Mena, and Nilimanka Das. "FORMULATION AND BIO-AVAILABILITY PARAMETERS OF PHARMACEUTICAL SUSPENSION." International Journal of Current Pharmaceutical Research 9, no. 3 (2017): 8. http://dx.doi.org/10.22159/ijcpr.2017.v9i3.18892.

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The suspension is a biphasic liquid or semi-solid dosage form where the finely divided insoluble solid drug particles are homogeneously dispersed in a liquid or semi-solid medium. The solid drug particles act here as the dispersed phase and the liquid or the semi-solid as the dispersion medium. Suspensions contribute to pharmaceutical dosage form development by supplying drugs that are insoluble in all acceptable medium and often distasteful. Suspension translates such drugs into more bio-available form when compared to capsules, tablets, coated tablets, enteric coated tablets and sustained re
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6

Nykänen, P., S. Lempää, M. L. Aaltonen, H. Jürjenson, P. Veski, and M. Marvola. "Citric acid as excipient in multiple-unit enteric-coated tablets for targeting drugs on the colon." International Journal of Pharmaceutics 229, no. 1-2 (2001): 155–62. http://dx.doi.org/10.1016/s0378-5173(01)00839-0.

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7

Induja, L., Aslam T. A., and G. Andhuvan. "PHARMACIST INTERVENTION AND PREPARATION OF MANUAL IN THE ADMINISTRATION OF DRUGS THROUGH ENTERAL FEEDING TUBE." International Journal of Pharmacy and Pharmaceutical Sciences 10, no. 12 (2018): 21. http://dx.doi.org/10.22159/ijpps.2018v10i12.27655.

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Objective: To monitor errors in current practice and prepare a manual for proper drug administration through the enteral feeding tube.Methods: It is a prospective observational study conducted for a period of 6 mo in eight departments. The current drug administrations were monitored and checked for the errors which include crushed non crushable solid dosage forms, each drug is not prepared separately, incorrect solution used for dilution, drugs mixed with feeding formula, each drug is not administered separately, not flushed before administration of each drug, not flushed after administration
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8

Xiong, Zhencheng, Ping Yi, Liubo Zhang, Haoning Ma, Wenhao Li, and Mingsheng Tan. "Efficacy and Safety of Modified Duhuo Jisheng Decoction in the Treatment of Lumbar Disc Herniation: A Systematic Review and Meta-Analysis." Evidence-Based Complementary and Alternative Medicine 2020 (July 4, 2020): 1–11. http://dx.doi.org/10.1155/2020/2381462.

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Objective. Lumbar disc herniation (LDH) is based on the degenerative changes of the intervertebral disc. Many drugs are used to treat and prevent LDH, including Western medicine and Chinese medicine. Duhuo Jisheng Decoction (DHJSD) is one of the most classic Chinese medicine prescriptions. The purpose of our meta-analysis is to evaluate the efficacy and safety of modified DHJSD in the treatment of LDH. Methods. We searched multiple databases including PubMed, Embase, Cochrane Library, China National Knowledge Infrastructure (CNKI) databases, Wanfang Database, and Chinese Scientific Journal Dat
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9

Pereira, Rosana Aparecida, Fabiana Bolela de Souza, Mayara Carvalho Godinho Rigobello, José Rafael Pereira, Laís Rosa Moreno da Costa, and Fernanda Raphael Escobar Gimenes. "Quality improvement programme reduces errors in oral medication preparation and administration through feeding tubes." BMJ Open Quality 9, no. 1 (2020): e000882. http://dx.doi.org/10.1136/bmjoq-2019-000882.

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BackgroundPatients with nasogastric/nasoenteric tube (NGT/NET) are at increased risk of adverse outcomes due to errors occurring during oral medication preparation and administration.AimTo implement a quality improvement programme to reduce the proportion of errors in oral medication preparation and administration through NGT/NET in adult patients.MethodsAn observational study was carried out, comparing outcome measures before and after implementation of the integrated quality programme to improve oral medication preparation and administration through NGT/NET. A collaborative approach based on
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10

Genç, Lütfi, Erden Güler, and Nahed Hegazy. "Film-Coated Enteric Tablet Formulation of Ketorolac Tromethamine." Drug Development and Industrial Pharmacy 23, no. 10 (1997): 1007–11. http://dx.doi.org/10.3109/03639049709149154.

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11

Okuda, Yutaka, Yasunobu Okamoto, Yosuke Irisawa, Kazuto Okimoto, Takashi Osawa, and Shinji Yamashita. "Formulation Design for Orally Disintegrating Tablets Containing Enteric-Coated Particles." Chemical and Pharmaceutical Bulletin 62, no. 5 (2014): 407–14. http://dx.doi.org/10.1248/cpb.c13-00752.

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12

Makino, Chisato, Hidetoshi Sakai, and Akira Yabuki. "Nateglinide Controlled Release Tablet Containing Compressionable Enteric Coated Granules." Chemical and Pharmaceutical Bulletin 58, no. 9 (2010): 1136–41. http://dx.doi.org/10.1248/cpb.58.1136.

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13

Down, G. R. B., S. Booth, W. Pfendner, and S. Ghodbane. "The Effect of Pinholes on the Dissolution Behaviour of Enteric-Coated Acetylsalicylic Acid Tablets." Drug Development and Industrial Pharmacy 19, no. 20 (1993): 2743–49. http://dx.doi.org/10.3109/03639049309050175.

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14

Rhee, Yun-Seok, Seok Park, Tae-Won Lee, et al. "Investigation of the relationship between in vitro and in vivo release behaviors of acamprosate from enteric-coated tablets." Archives of Pharmacal Research 31, no. 6 (2008): 798–804. http://dx.doi.org/10.1007/s12272-001-1229-y.

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15

Gu, Sizhen, Yan Xue, Yuli Zhang, et al. "An Investigation of the Mechanism of Rapid Relief of Ulcerative Colitis Induced by Five-flavor Sophora Flavescens Enteric-coated Capsules Based on Network Pharmacology." Combinatorial Chemistry & High Throughput Screening 23, no. 3 (2020): 239–52. http://dx.doi.org/10.2174/1386207323666200302121711.

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Aim and Objective: Five-Flavor Sophora flavescens Enteric-Coated Capsules (FSEC) are the only proprietary Chinese medicine approved for the treatment of ulcerative colitis (UC) in China. Phase II and III clinical trials have shown that the curative effect of FSEC in relieving UC was not inferior to that of mesalazine granules and enteric-coated tablets, but its pharmacological mechanism is unclear. Therefore, the network pharmacology is used to reveal the more comprehensive effective components and targets of FSEC in the treatment of UC. Methods: We screened the components of FSEC based on the
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16

Sun, Lu-Ning, Yi-Wen Shen, Yu-Wen Ying, et al. "Stereoselective pharmacokinetics of (R)-(+)- and (S)-(−)-rabeprazole in human using chiral LC-MS/MS after administration of rabeprazole sodium enteric-coated tablet." Chirality 30, no. 12 (2018): 1277–86. http://dx.doi.org/10.1002/chir.23022.

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17

Makino, Chisato, Nobutaka Ninomiya, Hidetoshi Sakai, Haruo Orita, Akira Okano, and Akira Yabuki. "Effect of Decrease in Both Postprandial Blood Glucose (PBG) and Fasting Blood Glucose (FBG) Levels in Normal Beagle Dogs with Nateglinide Enteric Coated Granules and Immediate Release Tablets." CHEMICAL & PHARMACEUTICAL BULLETIN 54, no. 4 (2006): 409–14. http://dx.doi.org/10.1248/cpb.54.409.

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18

Micheal, Francis, Mohanlal Sayana, Rajendra Prasad, and Balamurali Musuvathi Motilal. "Has the Time Come to Employ Population and Individual Bioequivalence for the Evaluation of Generics?" Current Drug Metabolism 21, no. 2 (2020): 112–25. http://dx.doi.org/10.2174/1389200221666200401105119.

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Background: Bioequivalence studies are a vital part of drug development. The average bioequivalence approach is the standard method of assessment to conclude whether the generic product is bioequivalent to the innovator product. Of late, debates are on whether the average bioequivalence approach adequately addresses drug interchangeability as it considers only population mean for the evaluation especially when highly variable drug products and narrow therapeutic index drugs are dealt with. Hence, the alternative approaches like population bioequivalence and individual bioequivalence assessment
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19

Endale, Abebe, Tsige Gebre-Mariam, and Peter C. Schmidt. "Granulation by Roller Compaction and Enteric Coated Tablet Formulation of the Extract of the Seeds of Glinus Lotoides Loaded on Aeroperl® 300 Pharma." AAPS PharmSciTech 9, no. 1 (2008): 31–38. http://dx.doi.org/10.1208/s12249-007-9027-3.

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20

Shaikh, Mohsina, Neha Desai, Munira Momin, and Lokesh Kumar Bhatt. "Formulation development and in-vitro/ex-vivo evaluation for a polysaccharide-based colon targeted matrix tablet." Current Drug Delivery 18 (July 8, 2021). http://dx.doi.org/10.2174/1567201818666210708121739.

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Objective: The objective of this study was to develop and optimize a microflora-triggered colon targeted sustained-release dosage form using gum ghatti (GG) and hydroxypropyl methylcellulose (HPMC K100). Methods: GG and HPMC K100 were used to prepare microflora triggered colon targeted sustained-release dosage form. For evaluation, two different tablets comprising metoprolol succinate and mesalamine as an active ingredient were used with the objective of developing a platform technology for various categories of drugs. The tablets were coated with Eudragit® L100 and Eudragit® S100 to provide e
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21

Deshmukh, Rohitas. "Development and In‑Vitro Evaluation of Colon Specific Indomethacin Matrix Tablet for the Treatment of Inflammatory Bowel Disease." Research Journal of Pharmacy and Technology, May 26, 2021, 2391–96. http://dx.doi.org/10.52711/0974-360x.2021.00422.

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IBD is a chronic inflammatory disease of the gastrointestinal tract, particularly small and large intestine consisting of ulcerative colitis (UC) and Crohn’s disease (CD). Oral route of drug delivery is considered as the most appropriate route of drug delivery of drugs. But this route has certain limitations of poor bioavailability due to gastric degradation and increase in dose size and frequency. Therefore, the present aim of the study is to prepare and evaluate Indomethacin loaded matrix tablet using guar gum, HPMC (release controlling polymer) and citric acid to facilitate the drug solubil
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22

Desai, Shubhamkar Ashok, and Prof R. N. Kale. "METHOD DEVELOPMENT AND VALIDATION OF MESALAMINE IN PHARMACEUTICAL DOSAGE FORM: A REVIEW." International Journal of Pharmaceutical and Biological Science Archive 7, no. 3 (2019). http://dx.doi.org/10.32553/ijpba.v7i3.130.

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Anti-inflammatory agents are the important class of drugs used in various commercial pharmaceutical formulations for the treatment of fever, inflammation and minor pain. One of the important anti-inflammatory drug is Mesalamine which belongs to the class of Amino-salicylic acid derivatives. Mesalamine is a bowel specific anti-inflammatory drug used in the treatment of inflammatory bowel diseases such as ulcerative colitis and Crohn’s disease.it is available in different pharmaceutical dosage forms such as delayed release, extend release and enteric coated tablets and capsulesetc., The several
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23

Srivastava, Vishal, Shivam Mishra, and Tapan K. Chaudhuri. "Enhanced production of recombinant serratiopeptidase in Escherichia coli and its characterization as a potential biosimilar to native biotherapeutic counterpart." Microbial Cell Factories 18, no. 1 (2019). http://dx.doi.org/10.1186/s12934-019-1267-x.

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Abstract Background Serratia marcescens, a Gram-negative nosocomial pathogen secretes a 50 kDa multi-domain zinc metalloprotease called serratiopeptidase. Broad substrate specificity of serratiopeptidase makes it suitable for detergent and food processing industries The protein shows potent anti-inflammatory, anti-edemic, analgesic, antibiofilm activity and sold as an individual or fixed-dose enteric-coated tablets combined with other drugs. Although controversial, serratiopeptidase as drug is used in the treatment of chronic sinusitis, carpal tunnel syndrome, sprains, torn ligaments, and post
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Hashmat, Durriya, M. Harris Shoaib, Zafar Alam Mehmood, Rabia Bushra, Rabia Ismail Yousuf, and Fahim Lakhani. "Development of Enteric Coated Flurbiprofen Tablets using Opadry/acryl-eze System—A Technical Note." AAPS PharmSciTech 9, no. 1 (2008). http://dx.doi.org/10.1208/s12249-007-9005-9.

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Maghrabia, Amir E., Mariza F. Boughdady, and Mahasen M. Meshali. "New Perspective Enteric-Coated Tablet Dosage Form for Oral Administration of Ceftriaxone: In Vitro and In Vivo Assessments." AAPS PharmSciTech 20, no. 7 (2019). http://dx.doi.org/10.1208/s12249-019-1512-y.

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