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Dissertations / Theses on the topic 'Enzymes; Lipids'

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1

Mateos, Diaz Eduardo. "Etude par spectroscopie infrarouge (FTIR) des interactions de la lipase pancréatique apparentée de type 2 (PLRP2) avec les phospholipides et les sels biliaires." Thesis, Aix-Marseille, 2016. http://www.theses.fr/2016AIXM4763.

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La lipase pancréatique apparentée de type 2 du cobaye (GPLRP2) hydrolyse une grande variété de substrats lipidiques. Elle montre cependant une sélectivité selon l’organisation supramoléculaire du substrat et la présence de surfactants comme les sels biliaires (NaTDC). Nous avons utilisé la spectroscopie infrarouge (FTIR) pour étudier les interactions entres les phospholipides (DPPC), les surfactants et la GPLRP2 dans des conditions expérimentales proches de celles du tractus digestif. Pour étudier l’étape d’adsorption indépendamment de l’hydrolyse, un variant inactif de GPLRP2 (S152G) a été pr
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2

Vlčková, Bohumila. "Testování komerčních přípravků do odlučovačů tuků." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2008. http://www.nusl.cz/ntk/nusl-216440.

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Diploma thesis was aimed at testing of five commercial products for separators of lipids. Performed study should to shown that in produts are presented lipase-produducing microoganisms, event. that in products are also lipolytics enzymes as addition. The products was cultivated by solid-state and submerged fermentations and subsequently was tested their properties as is lipolytic activity, the amount of free fatty acids etc. Solid-state fermentation used Tributyrin Agar Base where Tributyrin was used as a substrate. Submerged fermentation used special prepared medium where was olive oil. Metho
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3

Taylor, Samantha. "The modulation of cytochrome P450 activities by their membrane lipid environment." Thesis, University of Central Lancashire, 2001. http://clok.uclan.ac.uk/20846/.

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Cytochrome P450 (GYP) are a family of membrane-bound enzymes which form a component of the mixed function oxidase (MFO) system and are involved in the metabolism of many endogenous and exogenous compounds and, as such, play key roles in many physiological, pharmacological and toxicological processes. Due to the diversity of their substrates, it is essential to gain an understanding of how their activities can be modulated. The membrane lipid environment of CYP isoforms has proved to be an essential component for their optimal activities and consequently investigations into this aspect of modul
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4

Rogers, Julia Sarah. "The role of the stratum corneum lipids and enzymes in skin condition." Thesis, University College London (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.367557.

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5

Nordlund, Gustav. "Membrane-mimetic systems : Novel methods and results from studies of respiratory enzymes." Doctoral thesis, Stockholms universitet, Institutionen för biokemi och biofysik, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-94554.

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The processes localized to biological membranes are of great interest, both from a scientific and pharmaceutical point of view. Understanding aspects such as the detailed mechanism and regulation of these processes requires investigation of the structure and function of the membrane-bound proteins in which they take place. The study of these processes is often complicated by the need to create in vitro systems that mimic the environment in which these proteins are normally found in vivo. This thesis describes some of the methods available for membrane-protein studies in membrane-mimetic system
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6

Molina, Maria Isabel. "Enzymes and genes involved in biosynthesis of plant lipid polyesters." Diss., Connect to online resource - MSU authorized users, 2008.

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7

Ribeiro, Teresa Paula Costa. "Rational use of dietary enzymes and lipids to improve broiler performance and meat quality." Doctoral thesis, Universidade Técnica de Lisboa. Faculdade de Medicina Veterinária, 2011. http://hdl.handle.net/10400.5/3624.

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Tese de Doutoramento em Ciências Veterinárias. Especialidade de Ciências Biológicas e Biomédicas.<br>The importance of carbohydrate-binding modules (CBMs) and the use of novel enzymes with specific catalytic activities to improve the nutritive value of barley based diets for broilers and the effectiveness of a lipidic supplementation to improve the levels of benefic fatty acids in broilers meat remain to be investigated. In this work we studied the importance of a β-glucan binding domain (CBM11) when appended to three different enzymes (GH26GH5 and GH16, belonging to Clostridium thermocellum,
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8

Brand, N. "The evaluation of hand sanitizer formulations based on the characteristics of stratum corneum lipids processing enzymes." Thesis, University College London (University of London), 2017. http://discovery.ucl.ac.uk/1571899/.

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Hand hygiene is a major and fundamental topic in patient management to avoid health care-associated infections. According to the WHO alcohol-based hand rubs are the preferred means in clinical antisepsis. However, the frequent use of alcohol-based hand rubs can cause adverse events, which negatively impact user compliance, demonstrating a risk for patients. Adverse events are based on protein denaturation and stratum corneum lipid extraction. The aim of this work was to develop in vivo assays for lipid-processing enzymes in the stratum corneum as biomarkers to be routinely used in the evaluati
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9

Szpryngiel, Scarlett. "Structure and lipid interactions of membrane-associated glycosyltransferases : Cationic patches and anionic lipids regulate biomembrane binding of both GT-A and GT-B enzymes." Doctoral thesis, Stockholms universitet, Institutionen för biokemi och biofysik, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-131084.

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This thesis concerns work on structure and membrane interactions of enzymes involved in lipid synthesis, biomembrane and cell wall regulation and cell defense processes. These proteins, known as glycosyltransferases (GTs), are involved in the transfer of sugar moieties from nucleotide sugars to lipids or chitin polymers. Glycosyltransferases from three types of organisms have been investigated; one is responsible for vital lipid synthesis in Arabidopsis thaliana (atDGD2) and adjusts the lipid content in biomembranes if the plant experiences stressful growth conditions. This enzyme shares many
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10

Neal, Andrea C. "Lipid biosynthesis in eukaryotic cells : studies on enzyme activities involved in fatty acid activation and acylation /." Uppsala : Dept. of Plant Biology and Forest Genetics, Swedish University of Agricultural Sciences, 2006. http://epsilon.slu.se/200678.pdf.

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11

Clayton, Daniel John. "Spectroscopic studies of apolipoprotein e and the low-density lipoprotein receptor /." [St. Lucia, Qld.], 2001. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe16846.pdf.

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12

Zhao, Sheyun. "Induction of freezing tolerance in jack pine seedlings, changes in lipids, oxidation-reduction and antioxidant enzymes during cold acclimation." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp02/NQ35380.pdf.

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13

Romanová, Kristýna. "Proteomická identifikace enzymů degradující rostlinnou biomasu." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2011. http://www.nusl.cz/ntk/nusl-216797.

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The theoretical part of work is focused on the issue of biomass which can be used for energy purposes, inparticular agricultural waste, as well as can serve as a substrate for biogas station. It also deals with proteomics, its goals and approaches, separation methods. The aim of this work was to measure each sample of enzyme activity of biomass, which are used as a raw materials for biogas plants and their proteomic identification.
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14

Linde, Mona [Verfasser], Reinhard [Akademischer Betreuer] Sterner, Werner [Akademischer Betreuer] Kremer, and Christine [Akademischer Betreuer] Ziegler. "Characterization of Enzymes Involved in the Synthesis and Processing of Ether Lipids in Archaea and Bacteria / Mona Linde ; Reinhard Sterner, Werner Kremer, Christine Ziegler." Regensburg : Universitätsbibliothek Regensburg, 2017. http://d-nb.info/1137701730/34.

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15

Dudognon, Tony. "Relations entre la structure des lipides membranaires de mitochondries et l'activité d'enzymes associées chez l'huître creuse Crassostrea gigas." Phd thesis, Université de Bretagne occidentale - Brest, 2013. http://tel.archives-ouvertes.fr/tel-00969121.

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Tout d'abord considérés comme simples composants d'une barrière imperméable, il a été démontré que les lipides membranaires auraient en fait un rôle biologique bien plus important, pouvant modifier l'environnement des enzymes membranaires et moduler l'activité de ces dernières. Dans la thèse présentée ici, ces relations ont été étudiées dans les mitochondries de l'huître creuse Crassostrea gigas. Les bivalves subissent d'importants changements environnementaux et l'adaptation à ces changements peut passer par un remodelage des membranes, ce qui fait de ces animaux des modèles intéressants pour
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16

Benarouche, Anais. "Etude des interactions lipase-lipides au niveau d'interfaces modèles." Thesis, Aix-Marseille, 2013. http://www.theses.fr/2013AIXM4791.

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Les enzymes lipolytiques sont solubles en phase aqueuse mais hydrolysent des substrats insolubles. Leurs activités lipolytiques dépendent donc fortement de l’organisation des substrats lipidiques présents sous forme de structures interfaciales telles que des émulsions, des micelles, des liposomes, ou des bicouches lipidiques. Les propriétés cinétiques et la spécificité de substrat de ces enzymes résultent de l’étape initiale d’adsorption à l’interface lipide-eau et des interactions entre le substrat et le site actif. Dans le cadre de ce travail de thèse, la technique des films monomoléculaires
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17

YAMANE, Tsuneo. "Enzyme Engineering for Lipids." 名古屋大学農学国際教育協力研究センター, 2004. http://hdl.handle.net/2237/8930.

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18

Morla, Shravan. "Glycosaminoglycan Mimetics for the Treatment of Cancer and Lung Inflammation." VCU Scholars Compass, 2019. https://scholarscompass.vcu.edu/etd/5948.

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Glycosaminoglycans (GAGs) are linear polysaccharides whose disaccharide building blocks consist of an amino sugar and either uronic acid or galactose. They are expressed on virtually all mammalian cells, usually covalently attached to proteins, forming proteoglycans. GAGs are highly negatively charged due to an abundance of sulfate and carboxylic acid groups, and are structurally very diverse, with differences arising from chain length, the type of monomeric units, the linkages between each monomeric unit, the position of sulfate groups, and the degree of sulfation. GAGs are known to interact
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19

Bradáčová, Kristína. "Produkce lipolytických enzymů kvasinkami." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2018. http://www.nusl.cz/ntk/nusl-376871.

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This diploma thesis is focused on controlled production of lipolytic enzymes, bioactive substances and lipids by carotenogenic yeasts. Theoretical part deals with characterization of lipolytic enzymes, carotenoids, lipids and their properties, possibility of production and application. In experimental part the enzymes, carotenoids and lipids were produced by red yeasts Rhodotorula mucilaginosa, Cystofilobasidium macerans and Sporidiobolus salmonicolor by submerged cultivation in mineral medium with different additions: glucose, glycerol, fat, fat with glucose, fat with polysorbate 80, fat with
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20

Linscott, Kristin Brooke. "DISCOVERING A NOVEL ANTIFUNGAL TARGET IN DOWNSTREAM STEROL BIOSYNTHESIS USING A SQUALENE SYNTHASE FUNCTIONAL MOTIF." UKnowledge, 2017. http://uknowledge.uky.edu/biochem_etds/33.

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The sterol biosynthetic pathway is essential for growth of all eukaryotic cells and the main target of antifungal agents. The emergence of resistance to these antifungals in an already ill patient population indicates a need to develop drugs that have a broad spectrum of activity among pathogenic fungi and have minimal patient toxicity. Squalene synthase is the first committed step in the sterol pathway and has been studied intensively for development of antifungal agents. While the overall architecture of this enzyme is identical throughout eukaryotes, it was shown that plant and animal genes
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21

Keeler, Allison M. "Gene Therapy for Very Long Chain Acyl-coA Dehydrogenase Deficiency Using Adeno-Associated Virus Vectors: A Dissertation." eScholarship@UMMS, 2012. https://escholarship.umassmed.edu/gsbs_diss/632.

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Very long chain acyl-coA dehydrogenase (VLCAD) is the rate-limiting step in mitochondrial fatty acid oxidation. VLCAD deficient mice and patients’ clinical symptoms stem from not only an energy deficiency but also long-chain metabolite accumulations. VLCAD deficient mice were treated systemically with 1x10 12 vector genomes of rAAV9-VLCAD. Expression was detected in the liver, heart and muscle. Also substantial expression of VLCAD was noted in the brain, where it was expressed across different sections of the brain and in different cell types with different morphologies. Biochemical correction
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22

Kriegel, Sébastien. "Transformation of a membrane protein from the respiratory chain into a sensor for the analysis of its interaction with substrates, inhibitors and lipids." Phd thesis, Université de Strasbourg, 2013. http://tel.archives-ouvertes.fr/tel-01017392.

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The field of bioenergetics deals with the flow and transformation of energy within and between living organisms and their environment. The work presented in this thesis report focuses on cellular respiration and more specifically on the first enzyme of the respiratory chain, NADH:ubiquinone oxidoreductase (Complex I). This was done to clarify details about its function and its implication in disease. First, the creation of a sensor involving the biomimetically immobilized enzyme is presented and probed through a combination of surface enhanced infrared absorption spectroscopy (SEIRAS) and elec
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23

Kuitert, Lieske Meta Elizabeth. "Eicosanoid synthetic enzymes : aspects of regulation and expression in asthma." Thesis, Imperial College London, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.248441.

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24

Westin, Maria A. K. "Acyl-CoA thioesterases - auxiliary enzymes in peroxisomal lipid metabolism /." Stockholm, 2007. http://diss.kib.ki.se/2007/978-91-7357-241-5/.

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25

Santucci, Pierre. "Implication des enzymes lipolytiques dans la virulence et la survie mycobactérienne." Thesis, Aix-Marseille, 2018. http://www.theses.fr/2018AIXM0605.

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L’agent pathogène responsable de la tuberculose, Mycobacterium tuberculosis, utilise principalement les lipides comme source d’énergie lors du processus infectieux. Cela suggère que les enzymes lipolytiques (ELs) sont des facteurs d’une importance cruciale, qui jouent un rôle essentiel pour la survie et la persistance du bacille au sein des granulomes tuberculeux. Dans ce contexte, nous nous sommes intéressés au rôle physiologique de la protéine LipY (Rv3097c), une TAG-hydrolase apparentée à la lipase Hormono-sensible humaine. En utilisant un modèle expérimental de « foamy » macrophages, nous
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26

Gunnlaugsdottir, Helga. "Lipase-catalysed lipid modifications in supercritical carbon dioxide." Lund : Dept. of Food Technology, Lund University, 1997. http://catalog.hathitrust.org/api/volumes/oclc/39725780.html.

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27

Clark, Juliette A. "Subcellular distribution of lipid metabolising enzymes in human skeletal muscle." Thesis, University of Birmingham, 2012. http://etheses.bham.ac.uk//id/eprint/3378/.

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In obesity, lipids stored in muscle as lipid droplets (LDs) lead to accumulation of fatty acid (FA) metabolites and insulin resistance. This research involves development of immunofluorescence microscopy methods to generate novel information on the subcellular content and distribution of key enzymes that play a role in the underlying mechanisms. Chapters 3 and 4 describe visualisation of two lipid synthesising enzymes. Both are more abundant in type I muscle fibres. Chapter 5 reveals no differences between these enzymes in non obese and obese elderly women. Chapter 6 reveals that a key lipolyt
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28

Khili, Mouna. "Characterization of Value Added Proteins and Lipids form Microalgae." Thesis, Virginia Tech, 2013. http://hdl.handle.net/10919/49673.

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Microalgae have been so far identified as the major producers of organic matter through their photosynthetic activities. In the present work, Nannochloris sp. and Amphora sp., two marine microalgae, have been investigated for proteins and lipids production. Protein fraction was quantified using Bicinchoninic acid (BCA) assay. Protein content in Nannochloris sp. was 16.69 ±4.07 % of dry mass and in Amphora sp. it was 39.89 ±2.09 % of dry mass. Enzyme assays were conducted spectrophotometrically. Nannochloris sp. had malate dehydrogenase, peroxidase and catalase activities. Amphora sp. exhibited
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29

Huart, Pascal. "Influence de l'interaction lipides-agents antimiotiques sur l'activité des enzymes mitochondriaux." Doctoral thesis, Universite Libre de Bruxelles, 1990. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/213124.

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30

Tomas, Nicolas. "Recherche et caractérisation des enzymes-clés du processing des lipides mycobactériens." Thesis, Toulouse 3, 2020. http://www.theses.fr/2020TOU30072.

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La tuberculose causée par Mycobacterium tuberculosis (Mtu), est un problème de santé majeur aggravé par la résurgence inquiétante de souches de Mtu multirésistantes aux antibiotiques. Il est crucial de développer de nouvelles molécules antituberculeuses et de découvrir des cibles thérapeutiques. L'enveloppe de Mtu, atypique et très peu perméable, contient des acides mycoliques, acides gras à très longues chaines, qui sont essentiels et dont le métabolisme représente un réservoir de cibles validées. La dégradation de ces molécules, qui semble importante lors des mécanismes de l'infection de l'h
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31

Zhang, Zhi Jun. "Investigation into membrane lipid peroxidation and antioxidant defence enzymes in schizophrenia." Thesis, University of Sheffield, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.310764.

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32

Shackleton, Gareth Lloyd. "Linear alkyl benzene sulphonates : metabolism and induction of lipid metabolising enzymes." Thesis, University of Surrey, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.359897.

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33

Rowe, Daniel C. "Analysis of Toll-Like Receptor 4 Signal Transduction and IRF3 Activation in the Innate Immune Response: A Dissertation." eScholarship@UMMS, 2006. https://escholarship.umassmed.edu/gsbs_diss/163.

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Over the last decade, the innate immune system has been the subject of extensive research. Often overlooked by the robustness and specificity of the adaptive immune system, the innate immune system is proving to be just as complex. The identification of several families of pattern recognition receptors (PRRs) has revealed an ancient yet multifaceted system of proteins that are responsible for initiating host defense. A wide array of pathogens, from virus to bacteria, is detected using this assortment of receptors. One such family, the Toll-like receptors (TLRs), has been at the forefront of th
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34

Prima-Hartley, Valerie Georgette Bernadette. "Lipoxygenase activity in model food emulsion systems." Thesis, University of Nottingham, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.267669.

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35

Mekhalfi, Malika. "Production de lipides et étude de la régulation métabolique chez la diatomée Asterionella formosa." Thesis, Aix-Marseille, 2014. http://www.theses.fr/2014AIXM4770.

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La diatomée d'eau douce A. formosa peut produire des lipides neutres en plus ou moins grandes quantités en fonction des conditions de culture. Ainsi, nous avons montré par exemple qu'une carence en silice stimule la production de triacylglycérols (TAGs) mais génère une diminution de la biomasse. En revanche, nous avons montré que l'addition de bicarbonate et de phytohormones augmente à la fois la biomasse et la production de TAGs. L'ajout de phytohormones dans les milieux de culture de cette diatomée résulte en une augmentation de l'activité d'enzymes dans les extraits et notamment celles du c
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36

Ge, Changrong. "Property-controlling Enzymes at the Membrane Interface." Doctoral thesis, Stockholms universitet, Institutionen för biokemi och biofysik, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-61988.

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Monotopic proteins represent a specialized group of membrane proteins in that they are engaged in biochemical events taking place at the membrane interface. In particular, the monotopic lipid-synthesizing enzymes are able to synthesize amphiphilic lipid products by catalyzing two biochemically distinct molecules (substrates) at the membrane interface. Thus, from an evolutionary point of view, anchoring into the membrane interface enables monotopic enzymes to confer sensitivity to a changing environment by regulating their activities in the lipid biosynthetic pathways in order to maintain a cer
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37

Chang, Huey-Huey 1962. "Dietary fat effects on egg yolk lipid composition and hepatic lipogenic enzymes." Thesis, The University of Arizona, 1990. http://hdl.handle.net/10150/277290.

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Menhaden oil, corn oil, olive oil or animal fat (1, 3, 5 or 8% of diet) effects on egg yolk fatty acids and hepatic lipogenic enzymes were studied in 35 week-old laying hens. Except for significantly lowered egg weights by menhaden oil, performance was unaffected. Yolk saturated fat remained constant (33-38% of yolk fat) regardless of fat source. Maximum o-3 fatty acid incorporation (.31 g/yolk) was reached with a deposition efficiency of 36.3% by feeding 5% menhaden oil. Yolk lipid contained.3% linolenic (C18:3o3), 1.0% eicosapentaenoic (C20:5o3), and 3.8% docosapentaenoic (C22: 5o3) acids. M
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Macartney, Alastair Ian. "Cold adaptation of lipid biosynthetic enzymes in carp (Cyprinus carpio, L.) liver." Thesis, University of Liverpool, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.385150.

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Tempesta, Marie-Caroline. "Enzymologie des arylsulfatases lysosomiques et non lysosomiques. Métabolisme des sulfolipides dans les cellules en culture." Toulouse 3, 1993. http://www.theses.fr/1993TOU30163.

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Les arylsulfatases a et b sont des hydrolases lysosomiques intervenant dans la degradation des sulfolipides et des mucopolysaccharides. L'arylsulfatase c est une hydrolase cytosolique hydrolysant les steroides sulfates. Le deficit hereditaire de l'activite des arylsulfatases a, b et c est responsable, respectivement, de la leucodystrophie metachromatique, de la mucopolysaccharidose de type six et de l'ichtyose liee a l'x. Nous avons teste un nouveau modele experimental pour l'etude de ces maladies de surcharge: les lignees lymphoblastoides transformees par le virus d'epstein-barr. Nous avons d
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40

Batchelor, Rebecca. "The use of enzymes, isomerisable lipid analogues and small molecules to modulate the structure and dynamics of lipid bilayer." Thesis, University of Hull, 2010. http://hydra.hull.ac.uk/resources/hull:4689.

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A series of experiments were carried out to assess the effects and interactions of isomerisable lipid analogues, small molecules, and enzyme catalysed substrates on the structure and dynamics of lipid bilayers. Modulation of Enzyme Activity Using an Azobenzene-Containing Lipid Analogue – An azobenzene-containing phosphocholine lipid analogue (bis-Azo-PC) was synthesised and incorporated into 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) liposomes containing diacylglycerol kinase (DGK) in order to assess the effect of photoisomerisation of the azobenzene group on the activity of the protein.
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41

Savolainen, K. (Kalle). "α-Methylacyl-CoA racemase:an enzyme at crossroads in lipid metabolism". Doctoral thesis, University of Oulu, 2004. http://urn.fi/urn:isbn:9514274695.

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Abstract α-Methylacyl-CoA racemase (Amacr) is an enzyme at the merging point of two important pathways of lipid metabolism: elimination of methyl-branched fatty acids and synthesis of bile acids. Amacr is regarded as obligatory for these processes. Patients with Amacr-deficiency suffer from adult onset sensory motor neuropathy and/or severe neonatal cholestasis with coagulopathy and fat-soluble vitamin malabsorption. Amacr is also linked to cancer and so far has been proposed as a new marker for diagnosis of at least prostate and colon cancers. Common sources of phytol derived branched-chain f
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42

Mössinger, Christine. "Identification, regulation and physiological role of enzymes involved in triacylglycerol and phosphatidylcholine synthesis on lipid droplets." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2010. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-60606.

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Metabolic energy is most efficiently stored as triacylglycerol (TAG). This neutral lipid accumulates mainly within adipose tissues, but it can be stored and used in all types of cells. Within cells it is packed in organelles called lipid droplets (LDs). They consist of a core of neutral lipids like TAG and cholesterol esters, which is surrounded by a phospholipid monolayer that mainly consists of phosphatidylcholine (PC). Attached to or inserted into this monolayer are various proteins, mainly LD specific structural proteins or lipid metabolic enzymes. Though excess uptake of nutrition leads t
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43

Griffiths, Elinor Jane. "Effect of ischaemia on the activities of lipid metabolizing enzymes in perfused hearts from normal and diabetic rats." Thesis, University of Bath, 1989. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.236468.

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44

Hansen, Christine. "Synthesis of Modified and Labelled Lipids for Analysis of Enzyme Mechanisms and Membrane Interactions." Doctoral thesis, Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2017. http://hdl.handle.net/11858/00-1735-0000-0023-3F6F-F.

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45

Angsupanich, Kongkarn. "High pressure treatment effects on cod (Gadus Morhua) muscle." Thesis, University of Reading, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.265713.

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46

Karkalas, John. "The use of enzymes for the quantitative analysis of starch and amylose-lipid complexes." Thesis, University of Strathclyde, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.310894.

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47

Mössinger, Christine. "Identification, regulation and physiological role of enzymes involved in triacylglycerol and phosphatidylcholine synthesis on lipid droplets." Doctoral thesis, Max Planck Institute of Molecular Cell Biology and Genetics, 2009. https://tud.qucosa.de/id/qucosa%3A25375.

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Metabolic energy is most efficiently stored as triacylglycerol (TAG). This neutral lipid accumulates mainly within adipose tissues, but it can be stored and used in all types of cells. Within cells it is packed in organelles called lipid droplets (LDs). They consist of a core of neutral lipids like TAG and cholesterol esters, which is surrounded by a phospholipid monolayer that mainly consists of phosphatidylcholine (PC). Attached to or inserted into this monolayer are various proteins, mainly LD specific structural proteins or lipid metabolic enzymes. Though excess uptake of nutrition leads t
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Jónsson, Pétur. "Characterization of enzyme sensitive responsive hydrogel/lipid system for triggered release." Thesis, Uppsala universitet, Institutionen för farmaci, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-197521.

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This master thesis aimed to create and characterize multilayer coatings upon mesoporous silica particles (MSP). The properties of the coating aimed for, was to have a triggerable controlled release, where a targeted enzyme within the intestine, alpha-amylase, is supposed to degrade the coating. The coating was created from a bilayer consisting of DOTAP and DOPC in a 1:3 molar ratio, which serves as a protective coating. The second layer interacting with the surroundings consisted of a starch component, amylopectin, which is degraded by alpha-amylase. The study of the coating was performed with
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Alencar, Nara LÃdia Mendes. "MobilizaÃÃo de reservas endospÃrmicas de pinhÃo-manso durante a germinaÃÃo e desenvolvimento da plÃntula sob condiÃÃes de estresse salino." Universidade Federal do CearÃ, 2014. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=11759.

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Conselho Nacional de Desenvolvimento CientÃfico e TecnolÃgico<br>O pinhÃo-manso (Jatropha curcas L.) à uma planta oleaginosa, pertencente à famÃlia Euphorbiaceae, cujas sementes sÃo reconhecidas como matÃria-prima com potencial para a produÃÃo de Ãleo. Essa planta tambÃm à considerada tolerante a condiÃÃes adversas, tais como dÃficit hÃdrico e deficiÃncia nutricional do solo, o que favorece o seu cultivo em regiÃes Ãridas e semiÃridas. Objetivou-se avaliar os efeitos do estresse salino sobre a germinaÃÃo e a mobilizaÃÃo das reservas de sementes e plÃntulas de pinhÃo-manso, por meio de anÃlises
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Nguyen, Phuong Chi. "Deciphering antimycobacterial activity of cyclophostin/cyclipostins analogs and oxadiazolones derivatives, two new promising family compounds in the treatment of tuberculosis and mycobacterial-related diseases." Thesis, Aix-Marseille, 2018. http://www.theses.fr/2018AIXM0138.

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La tuberculose (TB) reste la maladie infectieuse la plus meurtrière au monde. L’absence de développement de médicaments accompagnée de l'émergence de la résistance aux molécules existantes se traduit principalement par l'échec du traitement et la mort. M. tb infecte l'homme par l'inhalation. Le patient peut rester en bonne santé sans aucun symptôme, on parle alors de tuberculose latente. Dans ce cas, la bactérie résider dans le macrophage. La principale caractéristique de M. tb est de rester cacher à l'intérieur de ces cellules, puis se réactiver lorsque le système immunitaire s’affaibli.Mon t
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