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Dissertations / Theses on the topic 'Enzymes Synthesis Genetic aspects'

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1

Maguire, Deborah Jane. "Studies on the 5-aminolevulinate synthase gene and its regulation /." Title page, contents and summary only, 1987. http://web4.library.adelaide.edu.au/theses/09PH/09phm213.pdf.

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2

Cotton, Kimberly Lynn. "Genetic and biochemical analysis of essential enzymes in triacylglycerol synthesis in arabidopsis." Thesis, Washington State University, 2016. http://pqdtopen.proquest.com/#viewpdf?dispub=10043101.

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<p> Plant oils are used in food, fuel, and feedstocks for many consumer products, and so understanding the process by which they are made and modified will help us to make plant oils more healthy, useful, and sustainable. While some of the genes encoding the ER-localized enzymatic steps to triacylglycerol (TAG) have been well understood and documented, several are still in need of study. The glycerol-3-phosphate acyl transferase (GPAT) enzymatic activity is the first step in the pathway to TAG, and it acylates glycerol 3-phosphate to produce lysophosphatidic acid. <i>GPAT9</i> (AT5G60620) is c
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3

Vousden, William Alexander. "Mutational analysis of the ACV synthetase gene of Aspergillus nidulans." Thesis, University of Sheffield, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.366097.

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4

Campeau, Eric. "Molecular genetics of biotin-dependent enzymes : mutation analysis, expression and biochemical studies." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0019/NQ55308.pdf.

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5

Murphy, Tracey L. "Developing a novel biocatalyst : N-acetylamino acid racemase." Thesis, Georgia Institute of Technology, 2002. http://hdl.handle.net/1853/32832.

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6

Surinya, Katharina Helen. "Heme biosynthesis in erythroid cells : transcriptional egulation of the human 5=aminolevulinate synthase 2 gene /." Title page, contents and summary only, 1997. http://web4.library.adelaide.edu.au/theses/09PH/09phs961.pdf.

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7

Cheung, Kwok-ho Alvin, and 張國豪. "Genetic and pharmacological approaches to study the role of the polyolpathway enzymes in diabetic and ischemic retinopathy." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B39558617.

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8

Healy, Helen Moira. "Studies on the regulation of the human hepatic 5-aminolevulinate synthase gene /." Title page, contents and introduction only, 1990. http://web4.library.adelaide.edu.au/theses/09PH/09phh4325.pdf.

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9

Braidotti, Giovanna. "Studies of the promoter region of the rat housekeeping 5-aminolevulinate synthase gene /." Title page, contents and summary only, 1992. http://web4.library.adelaide.edu.au/theses/09PH/09phb814.pdf.

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10

Morona, Judy Kay. "Characterisation of the capsular polysaccharide biosynthesis loci of streptococcus pneumoniae serogroup 19 /." Title page, contents and abstract only, 1998. http://web4.library.adelaide.edu.au/theses/09PH/09phm8678.pdf.

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11

Day, Adrienne Rose. "Characterization and expression of the chicken 5-Aminolevulinatesynthase gene /." Title page, contents and summary only, 1987. http://web4.library.adelaide.edu.au/theses/09PH/09phd2725.pdf.

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12

Abrahamsson, Anna. "Studies on the mechanism of regulation of bile acid synthesis in humans with some aspects on genetic factors /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-525-9/.

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13

Pavlovic, Renata [Verfasser], Eckhard [Gutachter] Boles, and Martin [Gutachter] Grininger. "Genetic modification of enzymes and metabolic pathways for the improvement of fatty acid synthesis in the yeast Saccharomyces cerevisiae / Renata Pavlovic ; Gutachter: Eckhard Boles, Martin Grininger." Frankfurt am Main : Universitätsbibliothek Johann Christian Senckenberg, 2017. http://d-nb.info/1130704467/34.

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14

Wyk, Paul. "Genetics of abequose biosynthesis in the rfb region of Salmonella typhimurium LT2 /." Title page, contents and abstract only, 1988. http://web4.library.adelaide.edu.au/theses/09PH/09phw981.pdf.

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15

Macpherson, Debbie Freda. "Characterization of the rfb region of Shigella flexneri /." Title page, abstract and contents only, 1995. http://web4.library.adelaide.edu.au/theses/09PH/09phm172.pdf.

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16

Yamanishi, Douglas Tadao. "The effect of chemical carcinogens on DNA bypass replication and the development of in vitro and in vivo models for chemical mutagenesis." Diss., The University of Arizona, 1989. http://hdl.handle.net/10150/184689.

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In the context of the somatic mutation theory of chemical carcinogenesis, mutations are thought to arise during the replication of DNA past carcinogen-DNA adducts. The work described in this thesis deals with the testing of a hypothetical mechanism whereby mammalian cells are able to replicate their DNA past polycyclic aromatic hydrocarbon DNA adducts. The second objective of this thesis work was to develop both in vivo and in vitro models to study the induction of mutations in a target human gene by chemical carcinogens from two different classes, polycyclic aromatic hydrocarbons and nitrosam
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17

Purins, Leanne Roslyn. "Molecular characterisation of the transcriptional activator, HLYU, of Vibrio cholerae O1 /." Title page, abstract and table of contents only, 2004. http://web4.library.adelaide.edu.au/theses/09PH/09php9857.pdf.

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Thesis (Ph.D.)--University of Adelaide, School of Molecular and Biomedical Science , Discipline of Microbiology and Immunology, 2005.<br>"May, 2004" Includes corrigenda. includes bibliographical references (leaves 118-156).
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18

Alm, Richard A. "Molecular characterization of the haemolysin determinant of Vibrio cholerae O1 /." Title page, contents and abstract only, 1989. http://web4.library.adelaide.edu.au/theses/09PH/09pha444.pdf.

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Thesis (Ph. D.)--University of Adelaide, Dept. of Microbiology and Immunology, 1990.<br>Includes an appendix of author's previously published papers. Includes bibliographical references (leaves 123-160).
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19

Daniels, Craig. "Characterisation of proteins involved in Shigella flexneri O-antigen biosynthesis." Title page, abstract and contents only, 1999. http://web4.library.adelaide.edu.au/theses/09PH/09phd186.pdf.

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Corrigenda pasted onto back end-papers. Bibliography: leaves 163-182. Analyses the proteins involved in Shigella flexneri O-antigen biosynthesis at the molecular level in order to gain a more concise understanding of the biosynthesis machinery and how it functions.
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20

Szekrényi, Anna. "Chemoenzymatic Synthesis of Carbohydrates and Derivatives with Engineered D-Fructose-6-Phosphate Aldolase." Doctoral thesis, Universitat de Barcelona, 2014. http://hdl.handle.net/10803/283141.

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Biocatalysis is the chemical transformation of organic substrates by enzymes. This is the driving force of some of the oldest transformations known to humans. Nowadays, methods involving biocatalysts are gaining importance in organic synthesis owing to their high efficiency and selectivity, and driven by the need to develop processes that are economical and environmentally sustainable. Recombinant DNA technology has paved the road for mass production of enzymes and recently their major limitation, i.e., narrow substrate spectrum is also being addressed by the development of enzyme engineering.
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21

Mavris, Maria. "Bacteriophage SfII mediated serotype conversion in Shigella flexneri /." Title page, abstract and contents only, 1998. http://web4.library.adelaide.edu.au/theses/09PH/09phm4608.pdf.

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22

Bao, Kogan K. "Kinetic analysis of avian sarcoma virus integrase in the presteady-state." Thesis, 2002. http://hdl.handle.net/1957/30239.

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Integrase catalyzes insertion of a retroviral genome into the host chromosome. Following reverse transcription, integrase binds specifically to the ends of the duplex retroviral DNA, endonucleolytically cleaves two nucleotides from each 3'-end (the processing activity), and inserts these ends into the host DNA (the joining activity) in a concerted manner. Additionally, it has been observed that integrase can catalyze the removal of inserted viral ends (the disintegration activity) in vitro. Presteady-state experiments were performed using synapsed substrates to probe the processing reaction an
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23

"Engineering feedback insensitive enzymes in lysine synthetic pathway of rice." 2011. http://library.cuhk.edu.hk/record=b5894505.

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Yu, Wai Han.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2011.<br>Includes bibliographical references (leaves 87-101).<br>Abstracts in English and Chinese.<br>ACKNOWLEDGEMENTS --- p.iii<br>ABSTRACT --- p.iv<br>摘要 --- p.vi<br>LIST OF CONTENTS --- p.viii<br>LIST OF FIGURES --- p.xii<br>LIST OF TABLES --- p.xiv<br>LIST OF ABBREVIATIONS --- p.xv<br>Chapter CHAPTER 1. --- GENERAL INTRODUCTION --- p.1<br>Chapter CHAPTER 2. --- LITERATURE REVIEW --- p.3<br>Chapter 2.1 --- The importance of rice --- p.3<br>Chapter 2.2 --- Limitation of essential amino acids in rice --- p.4<br>Chap
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24

"Proteomic study on the starch synthesis and regulation in developing hybrid rice seeds." 2006. http://library.cuhk.edu.hk/record=b5892918.

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Long Xiaohang.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2006.<br>Includes bibliographical references (leaves 132-155).<br>Abstracts in English and Chinese.<br>Thesis/Assessment Committee --- p.I<br>Statement from Author --- p.II<br>Acknowledgements --- p.III<br>Abstract --- p.V<br>摘要 --- p.VII<br>Table of Contents --- p.IX<br>List of Tables --- p.XV<br>List of Figures --- p.XVI<br>List of Abbreviations --- p.XVIII<br>Chapter Chapter 1 --- General Introduction and Literature Review --- p.1<br>Chapter 1.1 --- General introduction --- p.1<br>Chapter 1.2 --- Literature revi
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25

Collins, Laurence Vincent 1962. "The effect of mutations in lipopolysaccharide biosynthetic genes on the virulence of Salmonella typhimurium for the mouse / by Laurence Vincent Collins." 1990. http://hdl.handle.net/2440/19210.

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Bibliography: leaves 126-158.<br>158, [77] leaves (some folded), [19] leaves of plates : ill. ; 30 cm.<br>Title page, contents and abstract only. The complete thesis in print form is available from the University Library.<br>Thesis (Ph.D.)--University of Adelaide, Dept. of Microbiology and Immunology, 1991
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26

Cox, Timothy Chilton. "Heme biosynthesis in erythroid cells : regulation of 5-aminolevulinate synthase / by Timothy Chilton Cox." 1993. http://hdl.handle.net/2440/21445.

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Copies of author's previously published articles inserted.<br>Bibliography: leaves 197-212.<br>[xv], 212, [85] leaves, [11] leaves of plates : ill. ; 30 cm.<br>Title page, contents and abstract only. The complete thesis in print form is available from the University Library.<br>Thesis (Ph.D.)--University of Adelaide, Dept. of Biochemistry, 1993
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27

Brown, Melissa H. "Molecular characterization of the RFB region of Vibrio cholerea 01 (Ogawa) / Melissa H. Brown." 1991. http://hdl.handle.net/2440/19682.

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Includes bibliographical references.<br>ix, 118, [116] leaves, [5] leaves of plateas : ill. (some col.) ; 30 cm.<br>Title page, contents and abstract only. The complete thesis in print form is available from the University Library.<br>Thesis (Ph.D.)--University of Adelaide, Dept. of Microbiology and Immunology, 1992
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28

Tiwari, Sarika. "Expression of histone deacetylase enzymes in murine and chick optic nerve." Thesis, 2013. http://hdl.handle.net/1805/5045.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>Epigenetic alterations have been shown to control cell type specification and differentiation leading to the changes in chromatin structure and organization of many genes. HDACs have been well documented to play an important role in both neurogenesis and gliogenesis in ganglionic eminence and cortex-derived cultures. However, the role of HDACs in glial cell type specification and differentiation in the optic nerve has not been well described. As a first step towards understanding their role in glial cell type specification, we have e
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29

Tran, Elizabeth Ngoc Hoa. "Molecular characterisation of Shigella flexneri outer membrane protease IcsP." 2008. http://hdl.handle.net/2440/50043.

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Shigella is a genus of Gram-negative bacteria responsible for bacillary dysentery in humans. Shigella flexneri type 2a in particular is responsible for the majority of incidents in developing countries. The S. flexneri protease IcsP, is a member of the Omptin family of outer membrane (OM) proteases which cleaves IcsA, a polarly localised OM protein required for Shigella virulence. Mutations in icsP have been shown to effect the observed distribution of IcsA, however the significance of IcsP in Shigella virulence is incompletely understood. In this study, aspects of IcsP biology were investigat
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30

Vasan, Soumini. "Cascades of genetic instability resulting from compromised break-induced replication." Thesis, 2013. http://hdl.handle.net/1805/5047.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>Break-induced replication (BIR) is a mechanism to repair double-strand breaks (DSBs) that possess only a single end that can find homology in the genome. This situation can result from the collapse of replication forks or telomere erosion. BIR frequently produces various genetic instabilities including mutations, loss of heterozygosity, deletions, duplications, and template switching that can result in copy-number variations (CNVs). An important type of genomic rearrangement specifically linked to BIR is half crossovers (HCs), whic
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31

Bai, Yunpeng. "Understanding the biological function of phosphatases of regenerating liver, from biochemistry to physiology." Thesis, 2014. http://hdl.handle.net/1805/5675.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>Phosphatases of regenerating liver, consisting of PRL-1, PRL-2 and PRL-3, belong to a novel protein tyrosine phosphatases subfamily, whose overexpression promotes cell proliferation, migration and invasion and contributes to tumorigenesis and metastasis. However, although great efforts have been made to uncover the biological function of PRLs, limited knowledge is available on the underlying mechanism of PRLs’ actions, therapeutic value by targeting PRLs, as well as the physiological function of PRLs in vivo. To answer these questi
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32

Hendricks, Jeremiah William. "Inhibiting protein clearance to induce cell death in tuberous sclerosis and pancreatic cancer." Thesis, 2014. http://hdl.handle.net/1805/5389.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>Sequestration at the aggresome and degradation through autophagy are two approaches by which a cell can counteract the toxic effect of misfolded proteins. Tuberous sclerosis (TS) and cancer cells can become dependent on autophagy for survival due to the high demand for protein synthesis, thus making protein clearance a potential therapeutic target. Because of its histone deacetylase (HDAC) inhibitory activity, we hypothesized that 4-phenylbutyrate (4-PBA) inhibits HDAC6 and aggresome formation to induce TS cell death. We found that 4
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33

McCain, Travis William. "Vitamin D Inhibits Expression of Protein Arginine Deiminase 2 and 4 in Experimental Autoimmune Encephalomoyelitis Model Of Multiple Sclerosis." Thesis, 2014. http://hdl.handle.net/1805/6018.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>Multiple sclerosis (MS) is a disabling disease that afflicts an estimated two million people worldwide. The disease is characterized by degradation of the myelin sheath that insulates neurons of the central nervous system manifesting as a heterogeneous collection of symptoms. Two enzymes, protein arginine deaminases type 2 and 4 (PAD2 and PAD4) have been implicated to play an etiologic role in demyelination and neurodegeneration by catalyzing a post-translational modification of arginine peptide residues to citrulline. The pathogenes
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